Guide to the Human Genome
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Search of human proteins with 42734325

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42734325 wings apart-like homolog [Homo sapiens]
         (1190 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42734325 wings apart-like homolog [Homo sapiens]                  2390   0.0  
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    60   2e-08
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    42   0.003
gi|156104891 general transcription factor IIF, polypeptide 1, 74...    40   0.013
gi|89886480 zinedin isoform 2 [Homo sapiens]                           39   0.029
gi|89886477 zinedin isoform 1 [Homo sapiens]                           39   0.029
gi|122937227 U2-associated SR140 protein [Homo sapiens]                39   0.029
gi|62750354 matrin 3 [Homo sapiens]                                    37   0.11 
gi|21626466 matrin 3 [Homo sapiens]                                    37   0.11 
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap...    37   0.11 
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    37   0.15 
gi|122937261 coiled-coil domain containing 85A [Homo sapiens]          37   0.15 
gi|119943093 glycogenin 2 isoform a [Homo sapiens]                     36   0.19 
gi|119964690 glycogenin 2 isoform b [Homo sapiens]                     36   0.19 
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 36   0.25 
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]                   36   0.25 
gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]                     36   0.25 
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           36   0.25 
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           36   0.25 
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    35   0.33 
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                35   0.42 
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]                 35   0.42 
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]                   35   0.42 
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]                   35   0.42 
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap...    35   0.42 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    35   0.42 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    35   0.42 
gi|117414154 sodium channel associated protein 2 isoform b [Homo...    35   0.42 
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    35   0.42 
gi|55770834 centromere protein F [Homo sapiens]                        35   0.42 

>gi|42734325 wings apart-like homolog [Homo sapiens]
          Length = 1190

 Score = 2390 bits (6195), Expect = 0.0
 Identities = 1190/1190 (100%), Positives = 1190/1190 (100%)

Query: 1    MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPK 60
            MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPK
Sbjct: 1    MTSRFGKTYSRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPK 60

Query: 61   KPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKIS 120
            KPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKIS
Sbjct: 61   KPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKIS 120

Query: 121  HVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNS 180
            HVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNS
Sbjct: 121  HVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNS 180

Query: 181  HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWD 240
            HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWD
Sbjct: 181  HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWD 240

Query: 241  NDFEDIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRAN 300
            NDFEDIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRAN
Sbjct: 241  NDFEDIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRAN 300

Query: 301  KTKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTV 360
            KTKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTV
Sbjct: 301  KTKSSQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTV 360

Query: 361  LHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKS 420
            LHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKS
Sbjct: 361  LHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKS 420

Query: 421  KKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRT 480
            KKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRT
Sbjct: 421  KKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRT 480

Query: 481  KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTR 540
            KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTR
Sbjct: 481  KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTR 540

Query: 541  KIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPA 600
            KIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPA
Sbjct: 541  KIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPA 600

Query: 601  PPSKVIKTVTIPTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEY 660
            PPSKVIKTVTIPTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEY
Sbjct: 601  PPSKVIKTVTIPTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEY 660

Query: 661  LLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCT 720
            LLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCT
Sbjct: 661  LLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCT 720

Query: 721  AALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVH 780
            AALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVH
Sbjct: 721  AALMYILSRDRLNMDLDRASLDLMIRLLELEQDASSAKLLNEKDMNKIKEKIRRLCETVH 780

Query: 781  NKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDED 840
            NKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDED
Sbjct: 781  NKHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVDHLSRDED 840

Query: 841  EEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNR 900
            EEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNR
Sbjct: 841  EEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNR 900

Query: 901  AEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGT 960
            AEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGT
Sbjct: 901  AEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDNEWGSTKTGEQDGLIGT 960

Query: 961  ALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSICSGEG 1020
            ALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSICSGEG
Sbjct: 961  ALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCSFDSSICSGEG 1020

Query: 1021 DDSLRIGGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQ 1080
            DDSLRIGGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQ
Sbjct: 1021 DDSLRIGGQVHAVQALVQLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQ 1080

Query: 1081 WVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINV 1140
            WVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINV
Sbjct: 1081 WVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINV 1140

Query: 1141 TTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC 1190
            TTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC
Sbjct: 1141 TTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC 1190


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 83/464 (17%), Positives = 169/464 (36%), Gaps = 13/464 (2%)

Query: 76   DSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVVEDTVVSDKCFP 135
            DS D S    S N +    S  S+SS +++  + +   +++S  S     D+  S+    
Sbjct: 673  DSSDSSSSSDSSNSSD--SSDSSDSSNSSESSDSSDSSDSDSSDS----SDSSNSNSSDS 726

Query: 136  LEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPN 195
                      S+N     D+S SS +    SD  ++    +  +S     ++D S    +
Sbjct: 727  DSSNSSDSSDSSNSSDSSDSSDSSNS----SDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782

Query: 196  AETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSL 255
            +++  +S   +++D+ NS         S+ S    S  +   +  N  +   S +   S 
Sbjct: 783  SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSS 842

Query: 256  DSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGASNFDKLM 315
            DS    +  D D  NR ++ N +   D   S    ++      +N++ +S  +S+     
Sbjct: 843  DSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS-SNSSDSSDSSDSNESSNSSDSSDSSNSS 901

Query: 316  DGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQD 375
            D  S   + ++  S     + + +   S   S       + D +    S  S  +    D
Sbjct: 902  DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961

Query: 376  TMERS-MDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDH 434
            +   S   +  +S  +D   +      +D + S  ++    S+  S      +     D 
Sbjct: 962  SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021

Query: 435  ETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPES 494
                D   S  S+         D S+S D  D     +   S   + ++ S       +S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081

Query: 495  NDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKEN 538
            +++S DS   +N++++ D ++       S     +   D S  +
Sbjct: 1082 SESS-DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 110/531 (20%), Positives = 196/531 (36%), Gaps = 56/531 (10%)

Query: 10  SRKGGNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQKRPNFKPDIQEIPKKPKVEEEST 69
           S+  GNGS        +  +T  T   ++      G    N K D  +  K    + +S+
Sbjct: 498 SKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGND-DNDKSDSGK-GKSDSSDSDSS 555

Query: 70  GDPFGFDSDDESLPVSS-KNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVVEDTV 128
                 DS D S   SS  N +    SS S+SS+++  +   S   ++S  S    + + 
Sbjct: 556 DSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSD 615

Query: 129 VSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNAD 188
            SD      D+   +  S++   + D+S S  N   +SD  ++    +  NS     ++D
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDS--NSSDSSDNSDSSDSSNSSNSSDSSDSSD 673

Query: 189 DSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRS 248
            S    +++++ +S+  +++D+ NS         SE S              +D  D  S
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNS---------SESSD------------SSDSSDSDS 712

Query: 249 EDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGA 308
            D   S +S+      D D  N  ++ + +   D   S     +  +   ++ + SS  +
Sbjct: 713 SDSSDSSNSN----SSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768

Query: 309 SNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSV 368
            + D     +S +   +NS  S D  N +     S  +S       + D +    S  S 
Sbjct: 769 DSSD-----SSDSSDSSNSSDSNDSSNSSDSSD-SSNSSDSSNSSDSSDSSDSSDSDSS- 821

Query: 369 CNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEF 428
            N +       S D   +S  +D  ++      +D + S ++ R   SN+    D     
Sbjct: 822 -NSSDSSNSSDSSDSSNSSDSSDSSDS------SDGSDSDSSNRSDSSNSSDSSD----- 869

Query: 429 FGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSL 488
               D     D   S  SN         D S S D +  D      +S     +  S S 
Sbjct: 870 --SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES- 926

Query: 489 QPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENT 539
                S+DNS  S S +N++++ D ++       S     +   D S  N+
Sbjct: 927 ---SNSSDNSNSSDS-SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 78/473 (16%), Positives = 173/473 (36%), Gaps = 14/473 (2%)

Query: 65   EEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVV 124
            E   + D    DS D S   S+ N +    S+ S+SS+++   + +   ++++       
Sbjct: 700  ESSDSSDSSDSDSSDSS-DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758

Query: 125  EDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIH 184
             D+  S       D+    + S +    D ++ S  +    S    N  +  + +     
Sbjct: 759  SDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDS 818

Query: 185  KNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFE 244
             +++ S    +++++ +S   +++D+ +S  G   +S +       S  +   +  N  +
Sbjct: 819  DSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSD 878

Query: 245  DIRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKS 304
               S D   S +S    +  +    +  ++ N +   D   S     +  +   +N + S
Sbjct: 879  SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938

Query: 305  SQGASNFDKLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPS 364
            S  + + D   D ++ + +  +S+SS    +       S  +S       + D +    S
Sbjct: 939  SNSSDSSDS-SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997

Query: 365  CLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDV 424
              S  +    D+ + S D   +S  ++  ++      +D + S  ++    S+  S    
Sbjct: 998  SDSSNSSDSSDSSDSS-DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSN 1056

Query: 425  KLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAP 484
              +     D     D   S  S+         D SES D  D     +   S   + ++ 
Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSS---------DSSESSDSSDSSNSSDSSDSSDSSDSSD 1107

Query: 485  SPSLQPPPESND--NSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKS 535
            S       +S+D  NS DS   ++++++ D +        S     +   D S
Sbjct: 1108 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSS 1160



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 83/468 (17%), Positives = 171/468 (36%), Gaps = 33/468 (7%)

Query: 76   DSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHVVVEDTVVSDKCFP 135
            DS D S    S N +    SS S  S+++   + ++  +++   +     D+  SD    
Sbjct: 793  DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS--SDSSDG 850

Query: 136  LEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPN 195
             +     +  S+N     D+S SS +    SD  ++       NS     ++ DS+   +
Sbjct: 851  SDSDSSNRSDSSNSSDSSDSSDSSNS----SDSSDSSDSNESSNS----SDSSDSSNSSD 902

Query: 196  AETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSL 255
            ++++ +S   +++D+ NS       + S+ S    S  +   +  +  +   S D   S 
Sbjct: 903  SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSS--DSSDSSDSSNSSDSSNSS 960

Query: 256  DSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGASNFDKLM 315
            DS    +  D +  +  ++ N +   D   S             + +  S  +SN     
Sbjct: 961  DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDS-------------SDSSDSSDSSNSSDSS 1007

Query: 316  DGTSQALAKANSESSKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQD 375
            D +  + +  +S+SS    + +     S  +S       + D +    S  S  +    D
Sbjct: 1008 DSSDSSDSSNSSDSSNS--SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1065

Query: 376  TMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHE 435
            + + S D   +S  +D  E+      ++ + S  ++    S+  S      +     +  
Sbjct: 1066 SSDSS-DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124

Query: 436  TGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESN 495
               D   S  S+         D SES D  D     +   S   + ++ S       +S+
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1184

Query: 496  D-----NSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKEN 538
            D     +S DS   ++++++ D ++       S     +   D S  N
Sbjct: 1185 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSN 1232


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 42.0 bits (97), Expect = 0.003
 Identities = 50/228 (21%), Positives = 82/228 (35%), Gaps = 39/228 (17%)

Query: 400 KKADIATSKTTTRFRPSNTKSKKDVK----------------------LEFFGFEDHETG 437
           KK    + KT T F  +    KKD+K                      L   G  D E+ 
Sbjct: 200 KKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESI 259

Query: 438 GDEGG------SGSSNYKIKYFGFD------DLSESEDDEDDDCQVERKTSKKRTKTAPS 485
             +        + S NY +KY  +       +  +S D E +D +  +K SKK  K    
Sbjct: 260 NFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKK 319

Query: 486 PSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKENTRKIFSG 545
              +   + +  S D++SG +  E  D  +D     + +KK   K+  K    +    SG
Sbjct: 320 DDKKKDVKKDTESTDAESGDSKDERKDTKKD----KKKLKKDDKKKDTKKYPESTDTESG 375

Query: 546 PKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDD 593
             +       N +  +  D ++     +         L SKE +QKD+
Sbjct: 376 DAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE-SQKDE 422



 Score = 39.3 bits (90), Expect = 0.023
 Identities = 80/404 (19%), Positives = 144/404 (35%), Gaps = 39/404 (9%)

Query: 161 NKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPE 220
           +K I  +K +  +E  +      H+N      K ++ET   S+  +T     SQ  K+  
Sbjct: 144 SKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDKKDS 203

Query: 221 SPS-----EISPIKGSVRTGL--FEWDND-FEDIRSEDCILSLDSDPLLEMKDDD---FK 269
             S     E    K + +  L   +  ND   +I SE+  L++D   L+   DD+   F 
Sbjct: 204 KNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENS-LNVDFLMLVGQSDDESINFD 262

Query: 270 NRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGASNFDKLMDGTSQALAKANSES 329
             L N ++   ++      + T   T   A K+  ++   + D   D           + 
Sbjct: 263 AWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDK 322

Query: 330 SKDGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTP 389
            KD     +      G S        +D   L            +D  ++   ++  ST 
Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLK-----------KDDKKKDTKKYPESTD 371

Query: 390 ADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHETGGDEGGSGSSNYK 449
            + G+A   R       S+   +   ++ K K   K+ F    + E    E        K
Sbjct: 372 TESGDAKDARN-----DSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDK 426

Query: 450 IKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAE 509
                 +  S   D+E  D   E K   K+ K       +   + +D  +D++    NAE
Sbjct: 427 KDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKG-KKDSKKDDKKKDAK---KNAE 482

Query: 510 NLDFTEDLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKA 553
           + +   DL      +KK  +K+  K K+ ++K      R  T++
Sbjct: 483 STEMESDL-----ELKK--DKKHSKEKKGSKKDIKKDARKDTES 519


>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
           [Homo sapiens]
          Length = 517

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 56/250 (22%), Positives = 95/250 (38%), Gaps = 46/250 (18%)

Query: 373 IQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFE 432
           ++D +E S D   AS     G   + +KKA +A             K KK    +   FE
Sbjct: 210 LEDDLEMSSDASDASGEEG-GRVPKAKKKAPLAKG---------GRKKKKKKGSDDEAFE 259

Query: 433 DHETGGDEG--------GSGSSNYKIKYF-----------GFDDLSESEDDEDDDCQVER 473
           D + G  EG        GS SS  + +             G D+ S+S ++ +++   E 
Sbjct: 260 DSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEE 319

Query: 474 KTSKKRTKTAPSPSLQPPPESNDNSQDSQSG-----TNNAENLDFTEDLPGVPESVKKPI 528
              ++  K AP+P  Q      D+S++S S       + A +  F       P+  +KP 
Sbjct: 320 DKEEEEEKKAPTP--QEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKP- 376

Query: 529 NKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVK-------PQSVTV 581
              G  S+ N+R      +   T +   A        + +   P  K       PQS++ 
Sbjct: 377 --SGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSG 434

Query: 582 RLSSKEPNQK 591
           + + + P+ K
Sbjct: 435 KSTPQPPSGK 444


>gi|89886480 zinedin isoform 2 [Homo sapiens]
          Length = 760

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 19/61 (31%), Positives = 30/61 (49%)

Query: 462 EDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVP 521
           ++D D+D +++    KK+    PS +L P  E  D   DS+   N  + L   ED  G P
Sbjct: 273 DEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGAP 332

Query: 522 E 522
           +
Sbjct: 333 D 333


>gi|89886477 zinedin isoform 1 [Homo sapiens]
          Length = 753

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 19/61 (31%), Positives = 30/61 (49%)

Query: 462 EDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVP 521
           ++D D+D +++    KK+    PS +L P  E  D   DS+   N  + L   ED  G P
Sbjct: 273 DEDSDEDDELDSVQHKKQRVKLPSKALVPEMEDEDEEDDSEDAINEFDFLGSGEDGEGAP 332

Query: 522 E 522
           +
Sbjct: 333 D 333


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 13/121 (10%)

Query: 459  SESEDD-EDDDCQVERKTSKKRTKTAPSPS--------LQPPPESNDNSQDSQSGTNNAE 509
            S S+D  E D+C   RK  K+R  T+PSPS          P P+S  + +  +S   ++ 
Sbjct: 907  SRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSR 966

Query: 510  NLDFTEDLPGVPESVKKPINKQGDKSKENTRKIFS-GPKRSPTKAVYNAR--HWNHPDSE 566
            +    +D P    S K   +  G ++ + +R+  S  PK+S  K+   +R  H +H  S+
Sbjct: 967  SRSSHKDSPR-DVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSK 1025

Query: 567  E 567
            +
Sbjct: 1026 K 1026


>gi|62750354 matrin 3 [Homo sapiens]
          Length = 847

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 20/181 (11%)

Query: 63  KVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHV 122
           K +EE +G+    D+ D+        L +      SE       EE  ++LE+ S +   
Sbjct: 625 KEQEEKSGEDGEKDTKDDQTEQEPNMLLE------SEDELLVDEEEAAALLESGSSVG-- 676

Query: 123 VVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSC--NKLITSDKVENFHEEHEKNS 180
             ++T +++      D   GK++ +++ V+ D S S+    KL   DK+E   +E+E   
Sbjct: 677 --DETDLANLGDVASD---GKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAAL 731

Query: 181 HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPES---PSE--ISPIKGSVRTG 235
            +  KN +++     +        K+T++  + Q  +  +    P E  I P + +V  G
Sbjct: 732 ENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVG 791

Query: 236 L 236
           +
Sbjct: 792 I 792


>gi|21626466 matrin 3 [Homo sapiens]
          Length = 847

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 40/181 (22%), Positives = 79/181 (43%), Gaps = 20/181 (11%)

Query: 63  KVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISHV 122
           K +EE +G+    D+ D+        L +      SE       EE  ++LE+ S +   
Sbjct: 625 KEQEEKSGEDGEKDTKDDQTEQEPNMLLE------SEDELLVDEEEAAALLESGSSVG-- 676

Query: 123 VVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSC--NKLITSDKVENFHEEHEKNS 180
             ++T +++      D   GK++ +++ V+ D S S+    KL   DK+E   +E+E   
Sbjct: 677 --DETDLANLGDVASD---GKKEPSDKAVKKDGSASAAAKKKLKKVDKIEELDQENEAAL 731

Query: 181 HHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPES---PSE--ISPIKGSVRTG 235
            +  KN +++     +        K+T++  + Q  +  +    P E  I P + +V  G
Sbjct: 732 ENGIKNEENTEPGAESSENADDPNKDTSENADGQSDENKDDYTIPDEYRIGPYQPNVPVG 791

Query: 236 L 236
           +
Sbjct: 792 I 792


>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo
           sapiens]
          Length = 1555

 Score = 37.0 bits (84), Expect = 0.11
 Identities = 48/217 (22%), Positives = 83/217 (38%), Gaps = 20/217 (9%)

Query: 458 LSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDL 517
           L +  D +DDD + +RKT++K+ K           E   +S+   +G+ N       +  
Sbjct: 408 LQDKTDGKDDDVKEKRKTAEKKDK----------DEHMKSSEHRLAGSRNKIINGIVQKQ 457

Query: 518 PGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQ 577
             + E  +K   K G  S     +  S   RSP       R    P   +    P   P+
Sbjct: 458 DTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSPKRRDRRSPKRRQRSMSPTSTPK 517

Query: 578 SVTVRLSSKEPNQKDDGVFKAPAPPSKVIKTVTIPTQPYQDI--VTALKCRREDKELYTV 635
           +  +R S  + +  ++       PPS+  +     T+  QDI     +K   E++   T 
Sbjct: 518 AGKIRQSGAKQSHMEEF-----TPPSREDRNAKRSTK--QDIRDPRRMKKTEEERPQETT 570

Query: 636 VQH-VKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPL 671
            QH  K   +  E  EN + +   +   SG +  + L
Sbjct: 571 NQHSTKSGTEPKENVENWQSSKSAKRWKSGWEENKSL 607


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 37/152 (24%), Positives = 62/152 (40%), Gaps = 34/152 (22%)

Query: 459 SESEDDEDDDCQVERKTSKKRT---KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTE 515
           S SED   D+ + ++K  K +     + P PS  PPP+ +  +Q  +      + ++ +E
Sbjct: 265 SSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA-PPPKKSLGTQPPKKAVEKQQPVESSE 323

Query: 516 DLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVK 575
           D            + + D S E         K+ PTKAV          S+    PP  K
Sbjct: 324 D-----------SSDESDSSSEE-------EKKPPTKAVV---------SKATTKPPPAK 356

Query: 576 PQSVTVRLSSKEPNQKDDGVFKAPAPPSKVIK 607
             + +   SS   + +DD   +AP+ P+   K
Sbjct: 357 KAAESSSDSSDSDSSEDD---EAPSKPAGTTK 385



 Score = 35.8 bits (81), Expect = 0.25
 Identities = 34/160 (21%), Positives = 64/160 (40%), Gaps = 23/160 (14%)

Query: 456 DDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTE 515
           D  SE E  ++   ++   T K +TK  P P+   P  +N  +  S S ++++ + D +E
Sbjct: 172 DSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231

Query: 516 DLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVK 575
           +      + KK + K     K+   K       +PT+   ++   +  + EE        
Sbjct: 232 E-EKAAATPKKTVPK-----KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEE-------- 277

Query: 576 PQSVTVRLSSKEPNQKDDGVFKAPAPPSKVIKTVTIPTQP 615
                     K+P +   G + +  PPS      ++ TQP
Sbjct: 278 ---------QKKPMKNKPGPYSSVPPPSAPPPKKSLGTQP 308



 Score = 35.0 bits (79), Expect = 0.42
 Identities = 44/190 (23%), Positives = 68/190 (35%), Gaps = 36/190 (18%)

Query: 461 SEDDEDDDCQVERKTSKKRTKTAPS---------PSLQPPPESNDNSQDSQSGTNNAENL 511
           S  +E+     E KT K    T P          P+ Q P  S D+S DS S ++  E  
Sbjct: 424 SSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483

Query: 512 DFTED-------------LPGVPESVKK------PINKQGDKSKENTRKIF-------SG 545
             ++               P  P S KK        +   D S+E   K+          
Sbjct: 484 KTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQA 543

Query: 546 PKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPAPPSKV 605
           PK + T A+  A++     + E       K   V  +  S +  ++++   +A  P +K 
Sbjct: 544 PKANGTSAL-TAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK 602

Query: 606 IKTVTIPTQP 615
           IK  T  T P
Sbjct: 603 IKLQTPNTFP 612



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 32/130 (24%), Positives = 56/130 (43%), Gaps = 15/130 (11%)

Query: 459 SESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLP 518
           S+SED  +++ +V+   +KK    A    L PP ++   + +S S   ++++ D  ED  
Sbjct: 85  SDSEDSSEEEEEVQGPPAKKAAVPAKRVGL-PPGKAAAKASESSSSEESSDD-DDEEDQK 142

Query: 519 GVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQS 578
             P  V+K +  Q   +K   +K  S    S + +            +E P     K   
Sbjct: 143 KQP--VQKGVKPQAKAAKAPPKKAKSSDSDSDSSS-----------EDEPPKNQKPKITP 189

Query: 579 VTVRLSSKEP 588
           VTV+  +K P
Sbjct: 190 VTVKAQTKAP 199


>gi|122937261 coiled-coil domain containing 85A [Homo sapiens]
          Length = 553

 Score = 36.6 bits (83), Expect = 0.15
 Identities = 36/168 (21%), Positives = 64/168 (38%), Gaps = 30/168 (17%)

Query: 420 SKKDVKLEFFGFEDHETGGDEGGSGSS-------------------NYKIKYFGFDDLSE 460
           S + +K  + G  DH+ GG  GGSG S                   +++  Y G ++ S 
Sbjct: 358 SPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNE-ST 416

Query: 461 SEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTED---- 516
                  + +V +   + R     S + + PP  N ++ +   G+     L + +     
Sbjct: 417 LSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGI 476

Query: 517 ---LPGVPESVKKPINKQGDKSKENTRKIFSG---PKRSPTKAVYNAR 558
              LP +P S +      G  S  N+   FSG   P + P   V++ +
Sbjct: 477 GRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLK 524


>gi|119943093 glycogenin 2 isoform a [Homo sapiens]
          Length = 470

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 10/136 (7%)

Query: 44  LGQKRPNFKPDIQEIPKKPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSE-SSE 102
           LG  +P      Q +P+  ++ +E+   P G  S+D      ++  A + C   S+ S +
Sbjct: 316 LGSNQP-----AQGLPEPTQIVDETLSLPEGRRSEDMIACPETETPAVITCDPLSQPSPQ 370

Query: 103 AAQLEEVTSVLEANSKISHVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNK 162
            A   E  ++L+  +K+  V  E+T    +  P E     ++ S    +E D ++ S ++
Sbjct: 371 PADFTETETILQPANKVESVSSEETFEPSQELPAEAL---RDPSLQDALEVDLAV-SVSQ 426

Query: 163 LITSDKVENFHEEHEK 178
           +   +KV+    E E+
Sbjct: 427 ISIEEKVKELSPEEER 442


>gi|119964690 glycogenin 2 isoform b [Homo sapiens]
          Length = 501

 Score = 36.2 bits (82), Expect = 0.19
 Identities = 31/136 (22%), Positives = 62/136 (45%), Gaps = 10/136 (7%)

Query: 44  LGQKRPNFKPDIQEIPKKPKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSE-SSE 102
           LG  +P      Q +P+  ++ +E+   P G  S+D      ++  A + C   S+ S +
Sbjct: 347 LGSNQP-----AQGLPEPTQIVDETLSLPEGRRSEDMIACPETETPAVITCDPLSQPSPQ 401

Query: 103 AAQLEEVTSVLEANSKISHVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNK 162
            A   E  ++L+  +K+  V  E+T    +  P E     ++ S    +E D ++ S ++
Sbjct: 402 PADFTETETILQPANKVESVSSEETFEPSQELPAEAL---RDPSLQDALEVDLAV-SVSQ 457

Query: 163 LITSDKVENFHEEHEK 178
           +   +KV+    E E+
Sbjct: 458 ISIEEKVKELSPEEER 473


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 4/68 (5%)

Query: 479 RTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQGDKSKEN 538
           R    P+PS   PP++ D +++  S  N++E+ D+    PG     K P N QG  S ++
Sbjct: 749 RVSPPPAPS---PPKAPDTNKEDDSKDNDSES-DYMFMAPGAGAIPKNPRNPQGGSSSKS 804

Query: 539 TRKIFSGP 546
               FS P
Sbjct: 805 WSSYFSLP 812


>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
          Length = 681

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 28/111 (25%)

Query: 414 RPSNTKSKKDVKLEFFGFEDHETGGDEGG--------SGSSNYKIKYFGFDDLSESEDD- 464
           +  N + ++D+      FED ++  DEGG        SG S+  +KY  F D  ES++D 
Sbjct: 224 KDDNDEEEEDIDF----FEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDPVESDEDI 279

Query: 465 ------------EDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQS 503
                       EDD+   E       ++T     LQ   E+ DN Q  +S
Sbjct: 280 TNVHDDELDSNKEDDEIAEEEAEELSISETDEDDDLQ---ENEDNKQHKES 327


>gi|38016937 lemur tyrosine kinase 2 [Homo sapiens]
          Length = 1503

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 52/211 (24%), Positives = 84/211 (39%), Gaps = 32/211 (15%)

Query: 62   PKVEEESTGDPFGFDSDDESLPVSSKNLAQVKCSSYSESSEAAQLEEVTSVLEANSKISH 121
            P++ +E    PF    D  S     KNL  V+  +   S +AA+   + S L ++S    
Sbjct: 919  PELGQELHNKPFS--EDHHSHRRLEKNLEAVETLNQLNSKDAAKEAGLVSALSSDSTSQD 976

Query: 122  VVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSC-----NKLITSDKVENFHEEH 176
             ++ED++ +   FP  +  L    S   +   +A + S       KL+  DK  +   E 
Sbjct: 977  SLLEDSLSAP--FPASEPSLETPDSLESVDVHEALLDSLGSHTPQKLVPPDKPADSGYET 1034

Query: 177  EKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRP----------ESPSEIS 226
            E      +  + + T  P  E T  SE   T D  +S     P             +E++
Sbjct: 1035 E------NLESPEWTLHPAPEGTADSEPATTGDGGHSGLPPNPVIVISDAGDGHRGTEVT 1088

Query: 227  P------IKGSVRTGLFEWDNDFE-DIRSED 250
            P       +GS R   +  DND E + RSE+
Sbjct: 1089 PETFTAGSQGSYRDSAYFSDNDSEPEKRSEE 1119


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 25/144 (17%)

Query: 416 SNTKSKKDVKLEFFGFEDHETGG----DEGGSGSSNYK------------IKYFGFDDLS 459
           S+  SK++V  E +G  DHETG     DE G+ + N +            ++    +D  
Sbjct: 166 SSQSSKEEVNSEEYG-SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224

Query: 460 ESED--DEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDL 517
             ED  +E+++ + E +  ++  +           E ND    S++  + +E++ FT+  
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDG- 283

Query: 518 PGVPESVKKPINKQGDKSKENTRK 541
                SV+      G   K+  RK
Sbjct: 284 -----SVRSGSGTDGSDEKKKERK 302


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 35.8 bits (81), Expect = 0.25
 Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 25/144 (17%)

Query: 416 SNTKSKKDVKLEFFGFEDHETGG----DEGGSGSSNYK------------IKYFGFDDLS 459
           S+  SK++V  E +G  DHETG     DE G+ + N +            ++    +D  
Sbjct: 166 SSQSSKEEVNSEEYG-SDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEE 224

Query: 460 ESED--DEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDL 517
             ED  +E+++ + E +  ++  +           E ND    S++  + +E++ FT+  
Sbjct: 225 VDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDG- 283

Query: 518 PGVPESVKKPINKQGDKSKENTRK 541
                SV+      G   K+  RK
Sbjct: 284 -----SVRSGSGTDGSDEKKKERK 302


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 35.4 bits (80), Expect = 0.33
 Identities = 54/238 (22%), Positives = 97/238 (40%), Gaps = 37/238 (15%)

Query: 456 DDLSESED------DEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAE 509
           D  SE+ D         D  +V  +   + T  +P  S +  P      Q+SQ+G  N+ 
Sbjct: 675 DSKSEAPDPTQKAWSRSDSDEVPPRVPVRTTSRSPVLSRRDSPLQGSGQQNSQAGQRNST 734

Query: 510 NLDFTEDLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELP 569
           +   + +   + E V+K + + G  S   +    S P              +HP S+   
Sbjct: 735 S---SIEPRLLWERVEKLVPRPGSGSSSGSSNSGSQPG-------------SHPGSQSGS 778

Query: 570 GPPVVKPQSVTVRLSSKE---PNQKDDGVFKAPAPPSKVIKTVTIPTQPYQDI-VTAL-K 624
           G      +   VR SSK    P+Q+ +   K P    +V +    P +P  ++ +TAL K
Sbjct: 779 G------ERFRVRSSSKSEGSPSQRLENAVKKPEDKKEVFR----PLKPAGEVDLTALAK 828

Query: 625 CRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLA 682
             R  +++    +   + +   E G   E  DD+E   +   ++ P +TR  S ++L+
Sbjct: 829 ELRAVEDVRPPHKVTDYSSSSEESGTTDEEDDDVEQEGADESTSGPEDTRAASSLNLS 886


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 21/216 (9%)

Query: 147 TNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKE 206
           T    EDD+   S          +    E E+N   + K+ D+   +      V  +  E
Sbjct: 536 TKESEEDDSEKESDEDCSEKQSEDGSEREFEENG--LEKDLDEEGSEKELHENVLDKELE 593

Query: 207 TNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSLDSDPLLEMKDD 266
            ND+ NS+F    +   ++   +GS R   F+ D+D E    ED    +  D   E +D+
Sbjct: 594 ENDSENSEF--EDDGSEKVLDEEGSERE--FDEDSD-EKEEEEDTYEKVFDDESDEKEDE 648

Query: 267 DFKNR--LENLNEAIEEDIVQSVL---------RPTNCRTYCRANKTKSSQGASN---FD 312
           ++ +   LE  ++  EE      L            + +    A++       SN   FD
Sbjct: 649 EYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFD 708

Query: 313 KLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSF 348
           +  D + +    ++   +  G    ++G +S G+SF
Sbjct: 709 EEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSF 744



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 21/160 (13%)

Query: 174 EEHEKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVR 233
           ++  +  + +  + +DS KK + + T+ ++ +E      S+     ES  E+ P K S  
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE- 540

Query: 234 TGLFEWDNDFEDIRSEDCILSLDSD-PLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTN 292
                 ++D E    EDC      D    E +++  +  L+   E  E+++ ++VL    
Sbjct: 541 ------EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLD--EEGSEKELHENVL---- 588

Query: 293 CRTYCRANKTKSSQGASNFDKLMDGTSQALAKANSESSKD 332
                  +K      + N +   DG+ + L +  SE   D
Sbjct: 589 -------DKELEENDSENSEFEDDGSEKVLDEEGSEREFD 621


>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 46/216 (21%), Positives = 84/216 (38%), Gaps = 21/216 (9%)

Query: 147 TNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKE 206
           T    EDD+   S          +    E E+N   + K+ D+   +      V  +  E
Sbjct: 536 TKESEEDDSEKESDEDCSEKQSEDGSEREFEENG--LEKDLDEEGSEKELHENVLDKELE 593

Query: 207 TNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSLDSDPLLEMKDD 266
            ND+ NS+F    +   ++   +GS R   F+ D+D E    ED    +  D   E +D+
Sbjct: 594 ENDSENSEF--EDDGSEKVLDEEGSERE--FDEDSD-EKEEEEDTYEKVFDDESDEKEDE 648

Query: 267 DFKNR--LENLNEAIEEDIVQSVL---------RPTNCRTYCRANKTKSSQGASN---FD 312
           ++ +   LE  ++  EE      L            + +    A++       SN   FD
Sbjct: 649 EYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFD 708

Query: 313 KLMDGTSQALAKANSESSKDGLNQAKKGGVSCGTSF 348
           +  D + +    ++   +  G    ++G +S G+SF
Sbjct: 709 EEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTGSSF 744



 Score = 32.3 bits (72), Expect = 2.8
 Identities = 33/160 (20%), Positives = 66/160 (41%), Gaps = 21/160 (13%)

Query: 174 EEHEKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVR 233
           ++  +  + +  + +DS KK + + T+ ++ +E      S+     ES  E+ P K S  
Sbjct: 482 QKESEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESE- 540

Query: 234 TGLFEWDNDFEDIRSEDCILSLDSD-PLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTN 292
                 ++D E    EDC      D    E +++  +  L+   E  E+++ ++VL    
Sbjct: 541 ------EDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLD--EEGSEKELHENVL---- 588

Query: 293 CRTYCRANKTKSSQGASNFDKLMDGTSQALAKANSESSKD 332
                  +K      + N +   DG+ + L +  SE   D
Sbjct: 589 -------DKELEENDSENSEFEDDGSEKVLDEEGSEREFD 621


>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
          Length = 259

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 456 DDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQ-SGTNNAENLDFT 514
           DD  + +DD DD+   E+   KK  +  P+ + Q   +SN N +DS+ S T  ++  +  
Sbjct: 172 DDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQ---KSNQNGKDSKPSSTPRSKGQESF 228

Query: 515 EDLPGVPESVKKPINKQGDKSK 536
           +     P++ K P + +  K+K
Sbjct: 229 KKQEKTPKTPKGPSSVEDIKAK 250



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 23/100 (23%), Positives = 45/100 (45%), Gaps = 10/100 (10%)

Query: 459 SESEDDEDDDCQVERKTSKKRT----KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFT 514
           +ESED+E++D ++   + K+         P   ++   + +D+  D +    + ++ DF 
Sbjct: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182

Query: 515 EDLPGVPESVKKPIN----KQGDKSKENTRKIFSGPKRSP 550
           ++       VKK I     K   KS +N +   S P  +P
Sbjct: 183 DEEAEEKAPVKKSIRDTPAKNAQKSNQNGKD--SKPSSTP 220


>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
          Length = 294

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 456 DDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQ-SGTNNAENLDFT 514
           DD  + +DD DD+   E+   KK  +  P+ + Q   +SN N +DS+ S T  ++  +  
Sbjct: 172 DDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQ---KSNQNGKDSKPSSTPRSKGQESF 228

Query: 515 EDLPGVPESVKKPINKQGDKSK 536
           +     P++ K P + +  K+K
Sbjct: 229 KKQEKTPKTPKGPSSVEDIKAK 250



 Score = 31.6 bits (70), Expect = 4.7
 Identities = 23/100 (23%), Positives = 45/100 (45%), Gaps = 10/100 (10%)

Query: 459 SESEDDEDDDCQVERKTSKKRT----KTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFT 514
           +ESED+E++D ++   + K+         P   ++   + +D+  D +    + ++ DF 
Sbjct: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182

Query: 515 EDLPGVPESVKKPIN----KQGDKSKENTRKIFSGPKRSP 550
           ++       VKK I     K   KS +N +   S P  +P
Sbjct: 183 DEEAEEKAPVKKSIRDTPAKNAQKSNQNGKD--SKPSSTP 220


>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
           sapiens]
          Length = 2462

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 49/244 (20%), Positives = 80/244 (32%), Gaps = 42/244 (17%)

Query: 438 GDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVERKTSKKRTKTAPSPSLQP--PPESN 495
           G +  S   N+   Y    +L E         + ER   +K+ K   + S +   PP   
Sbjct: 642 GSKTVSQCKNFYFNYKKRQNLDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVE 701

Query: 496 DNSQDSQSGTNNAENL----DFTEDLPGVPESVKKPINKQGDKSKENTRKIFSGPKRSPT 551
           D   ++   + N E +    + T +     ES+  P  +    + +N      GPK   T
Sbjct: 702 DEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQN------GPKPPAT 755

Query: 552 KAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKDDGVFKAPAPPSKVIKTVTI 611
                            PGPP   P+ +         ++        PAPPS       +
Sbjct: 756 LGADGPP----------PGPPTPPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVV 805

Query: 612 PTQPYQDIVTALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPL 671
           P              +E+KE  T           VE GE Q+     E  +   K+ +P+
Sbjct: 806 P--------------KEEKEEETAAA------PPVEEGEEQKPPAAEELAVDTGKAEEPV 845

Query: 672 NTRC 675
            + C
Sbjct: 846 KSEC 849


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 88/440 (20%), Positives = 172/440 (39%), Gaps = 62/440 (14%)

Query: 190  STKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSV----RTGLFEWDNDFED 245
            STK+  A+ T +S     +D  NS  G+      +I P+  ++     TG  +   D  +
Sbjct: 1154 STKRKQADITSSSSSDIEDDDQNS-IGEGSSDEQKIKPVTENLVLSSHTGFCQSSGD--E 1210

Query: 246  IRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSS 305
              S+   +++D D      D+D +NR+    + + E+I  ++    +  +     + K  
Sbjct: 1211 ALSKSVPVTVDDDD----DDNDPENRIAK--KMLLEEIKANLSSDEDGSSDDEPEEGKKR 1264

Query: 306  QGASNFDKLMDGTSQALAKANSESSKDGLNQAK----------KGGVSCGTSFRGTVGRT 355
             G  N +    G  +A  + NSES  D     K          K  VS G S      + 
Sbjct: 1265 TGKQNEEN--PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP 1322

Query: 356  RDYTVL---HPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTR 412
            +++  +   +   +S  +    D  E  + E  + +  +     R  KKA++  ++ + +
Sbjct: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382

Query: 413  FRPSNTKSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVE 472
             +    K ++ +K++     ++++  +E        + +    ++  E E+DE+DD +  
Sbjct: 1383 QK----KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE---EEEEEEEEDENDDSKSP 1435

Query: 473  RKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQG 532
             K  KK  K      L             ++ T NA   +         E  +K I ++ 
Sbjct: 1436 GKGRKKIRKILKDDKL-------------RTETQNALKEE---------EERRKRIAER- 1472

Query: 533  DKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKD 592
            ++ +E  R++      SPTK     +     D EE   P V   +++ ++L   +P+Q D
Sbjct: 1473 EREREKLREVIEIEDASPTKCPITTKLVLDED-EETKEPLVQVHRNMVIKL---KPHQVD 1528

Query: 593  DGVFKAPAPPSKVIKTVTIP 612
               F        V KT   P
Sbjct: 1529 GVQFMWDCCCESVKKTKKSP 1548



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 454  GFDDLSES---EDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAEN 510
            G  D++E    +D  D+  + ++K SKK T+    PS     +     Q  +S ++  E 
Sbjct: 922  GLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS-DFKKKVIKMEQQYESSSDGTEK 980

Query: 511  LDFTEDLPGVPESVKKPINKQGDKSKENTR 540
            L   E++   P+ +K+  N   D  K++ +
Sbjct: 981  LPEREEICHFPKGIKQIKNGTTDGEKKSKK 1010


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 88/440 (20%), Positives = 172/440 (39%), Gaps = 62/440 (14%)

Query: 190  STKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSV----RTGLFEWDNDFED 245
            STK+  A+ T +S     +D  NS  G+      +I P+  ++     TG  +   D  +
Sbjct: 1192 STKRKQADITSSSSSDIEDDDQNS-IGEGSSDEQKIKPVTENLVLSSHTGFCQSSGD--E 1248

Query: 246  IRSEDCILSLDSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSS 305
              S+   +++D D      D+D +NR+    + + E+I  ++    +  +     + K  
Sbjct: 1249 ALSKSVPVTVDDDD----DDNDPENRIAK--KMLLEEIKANLSSDEDGSSDDEPEEGKKR 1302

Query: 306  QGASNFDKLMDGTSQALAKANSESSKDGLNQAK----------KGGVSCGTSFRGTVGRT 355
             G  N +    G  +A  + NSES  D     K          K  VS G S      + 
Sbjct: 1303 TGKQNEEN--PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP 1360

Query: 356  RDYTVL---HPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGRLRKKADIATSKTTTR 412
            +++  +   +   +S  +    D  E  + E  + +  +     R  KKA++  ++ + +
Sbjct: 1361 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1420

Query: 413  FRPSNTKSKKDVKLEFFGFEDHETGGDEGGSGSSNYKIKYFGFDDLSESEDDEDDDCQVE 472
             +    K ++ +K++     ++++  +E        + +    ++  E E+DE+DD +  
Sbjct: 1421 QK----KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEE---EEEEEEEEDENDDSKSP 1473

Query: 473  RKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVPESVKKPINKQG 532
             K  KK  K      L             ++ T NA   +         E  +K I ++ 
Sbjct: 1474 GKGRKKIRKILKDDKL-------------RTETQNALKEE---------EERRKRIAER- 1510

Query: 533  DKSKENTRKIFSGPKRSPTKAVYNARHWNHPDSEELPGPPVVKPQSVTVRLSSKEPNQKD 592
            ++ +E  R++      SPTK     +     D EE   P V   +++ ++L   +P+Q D
Sbjct: 1511 EREREKLREVIEIEDASPTKCPITTKLVLDED-EETKEPLVQVHRNMVIKL---KPHQVD 1566

Query: 593  DGVFKAPAPPSKVIKTVTIP 612
               F        V KT   P
Sbjct: 1567 GVQFMWDCCCESVKKTKKSP 1586



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 22/90 (24%), Positives = 42/90 (46%), Gaps = 4/90 (4%)

Query: 454  GFDDLSES---EDDEDDDCQVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAEN 510
            G  D++E    +D  D+  + ++K SKK T+    PS     +     Q  +S ++  E 
Sbjct: 960  GLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS-DFKKKVIKMEQQYESSSDGTEK 1018

Query: 511  LDFTEDLPGVPESVKKPINKQGDKSKENTR 540
            L   E++   P+ +K+  N   D  K++ +
Sbjct: 1019 LPEREEICHFPKGIKQIKNGTTDGEKKSKK 1048


>gi|117414154 sodium channel associated protein 2 isoform b [Homo
           sapiens]
          Length = 939

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 31/158 (19%), Positives = 61/158 (38%), Gaps = 1/158 (0%)

Query: 136 LEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPN 195
           L+D L  K++   R+ E    I  C +    +K     E  EK   H ++  +   ++  
Sbjct: 736 LKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH-NERKEKLKQQLK 794

Query: 196 AETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSL 255
            +     EI++   T N ++  + E    +      V+      +   +  R +   L  
Sbjct: 795 GKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQK 854

Query: 256 DSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNC 293
           ++   L   DD FK +++ + EA + +I Q       C
Sbjct: 855 NAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKC 892


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 31/158 (19%), Positives = 61/158 (38%), Gaps = 1/158 (0%)

Query: 136 LEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPN 195
           L+D L  K++   R+ E    I  C +    +K     E  EK   H ++  +   ++  
Sbjct: 829 LKDCLQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH-NERKEKLKQQLK 887

Query: 196 AETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSL 255
            +     EI++   T N ++  + E    +      V+      +   +  R +   L  
Sbjct: 888 GKEVELEEIRKAYSTLNRKWHDKGELLCHLETQVKEVKEKFENKEKKLKAERDKSIELQK 947

Query: 256 DSDPLLEMKDDDFKNRLENLNEAIEEDIVQSVLRPTNC 293
           ++   L   DD FK +++ + EA + +I Q       C
Sbjct: 948 NAMEKLHSMDDAFKRQVDAIVEAHQAEIAQLANEKQKC 985


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 35.0 bits (79), Expect = 0.42
 Identities = 31/145 (21%), Positives = 60/145 (41%), Gaps = 10/145 (6%)

Query: 114  EANSKISHVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFH 173
            E +SK+    V+     + C  LE  ++G+ K  N  + +     SC+      +VE   
Sbjct: 1806 ELDSKLHLQEVQLMTKIEACIELEK-IVGELKKENSDLSEKLEYFSCDHQELLQRVET-- 1862

Query: 174  EEHEKNSHHIHKNADDSTKKPNAETTVASEIKETNDTWNSQFGKRPESPSEISPIKGSVR 233
               E  +  +  +AD S+++      +   + + ND+W  +F       S I   K S+ 
Sbjct: 1863 --SEGLNSDLEMHADKSSRED-----IGDNVAKVNDSWKERFLDVENELSRIRSEKASIE 1915

Query: 234  TGLFEWDNDFEDIRSEDCILSLDSD 258
                  + D E +++E   L  D++
Sbjct: 1916 HEALYLEADLEVVQTEKLCLEKDNE 1940


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,322,446
Number of Sequences: 37866
Number of extensions: 2222804
Number of successful extensions: 10011
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 179
Number of HSP's that attempted gapping in prelim test: 9464
Number of HSP's gapped (non-prelim): 673
length of query: 1190
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1076
effective length of database: 13,930,794
effective search space: 14989534344
effective search space used: 14989534344
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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