Search of human proteins with 42519916

Search of human proteins with 42519916

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42519916 forkhead box O3A [Homo sapiens]
         (673 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42519916 forkhead box O3A [Homo sapiens]                          1343   0.0  
gi|4503739 forkhead box O3A [Homo sapiens]                           1343   0.0  
gi|9257222 forkhead box O1 [Homo sapiens]                             497   e-140
gi|103472003 forkhead box O4 [Homo sapiens]                           352   5e-97
gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]        319   5e-87
gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]     305   9e-83
gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]        145   2e-34
gi|208431824 forkhead box I3 [Homo sapiens]                            98   2e-20
gi|4758392 forkhead box D1 [Homo sapiens]                              90   6e-18
gi|195947376 forkhead box I2 [Homo sapiens]                            90   8e-18
gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]                   88   2e-17
gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]                  88   2e-17
gi|32307177 forkhead box G1 [Homo sapiens]                             88   2e-17
gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]                   87   4e-17
gi|50345831 forkhead box J3 [Homo sapiens]                             86   9e-17
gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]                   85   2e-16
gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]                   85   2e-16
gi|12751477 forkhead box L2 [Homo sapiens]                             84   3e-16
gi|24497501 forkhead box A1 [Homo sapiens]                             84   4e-16
gi|8923842 forkhead box J2 [Homo sapiens]                              84   4e-16
gi|145309320 forkhead box Q1 [Homo sapiens]                            83   7e-16
gi|134142824 forkhead box D2 [Homo sapiens]                            82   1e-15
gi|24497506 forkhead box A3 [Homo sapiens]                             82   1e-15
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]          80   8e-15
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]           80   8e-15
gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]                   79   1e-14
gi|4557595 forkhead box F2 [Homo sapiens]                              78   2e-14
gi|110735445 forkhead box F1 [Homo sapiens]                            77   4e-14
gi|21618327 forkhead box I1 isoform a [Homo sapiens]                   77   5e-14
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   75   2e-13

>gi|42519916 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 1343 bits (3475), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1   MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE 60
           MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
Sbjct: 1   MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE 60

Query: 61  EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS 120
           EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS
Sbjct: 61  EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS 120

Query: 121 GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL 180
           GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL
Sbjct: 121 GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL 180

Query: 181 SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG 240
           SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG
Sbjct: 181 SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG 240

Query: 241 GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS 300
           GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS
Sbjct: 241 GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS 300

Query: 301 DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK 360
           DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK
Sbjct: 301 DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK 360

Query: 361 PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG 420
           PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG
Sbjct: 361 PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG 420

Query: 421 SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS 480
           SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS
Sbjct: 421 SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS 480

Query: 481 HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT 540
           HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT
Sbjct: 481 HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT 540

Query: 541 QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP 600
           QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP
Sbjct: 541 QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP 600

Query: 601 VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT 660
           VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT
Sbjct: 601 VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT 660

Query: 661 GAKQASSQSWVPG 673
           GAKQASSQSWVPG
Sbjct: 661 GAKQASSQSWVPG 673


>gi|4503739 forkhead box O3A [Homo sapiens]
          Length = 673

 Score = 1343 bits (3475), Expect = 0.0
 Identities = 673/673 (100%), Positives = 673/673 (100%)

Query: 1   MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE 60
           MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE
Sbjct: 1   MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEE 60

Query: 61  EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS 120
           EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS
Sbjct: 61  EDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLS 120

Query: 121 GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL 180
           GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL
Sbjct: 121 GGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTL 180

Query: 181 SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG 240
           SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG
Sbjct: 181 SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDG 240

Query: 241 GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS 300
           GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS
Sbjct: 241 GKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSS 300

Query: 301 DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK 360
           DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK
Sbjct: 301 DELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSK 360

Query: 361 PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG 420
           PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG
Sbjct: 361 PCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKG 420

Query: 421 SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS 480
           SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS
Sbjct: 421 SGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDSLS 480

Query: 481 HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT 540
           HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT
Sbjct: 481 HSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQT 540

Query: 541 QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP 600
           QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP
Sbjct: 541 QGALGGSRALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLSDSLSGSSLYSTSANLP 600

Query: 601 VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT 660
           VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT
Sbjct: 601 VMGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFT 660

Query: 661 GAKQASSQSWVPG 673
           GAKQASSQSWVPG
Sbjct: 661 GAKQASSQSWVPG 673


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score =  497 bits (1279), Expect = e-140
 Identities = 323/698 (46%), Positives = 416/698 (59%), Gaps = 82/698 (11%)

Query: 12  SPLEVELDPEFEPQSRPRSCTWPLQRPELQ------ASPAKPSGETAADSMIPEEEDDED 65
           +P  VE+DP+FEP  RPRSCTWPL RPE        +SPA PSG  AA+           
Sbjct: 4   APQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPA-PSGSAAANP---------- 52

Query: 66  DEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAA---GGLSGG 122
           D   G  + SA A+     S      LL E      APG        A AA   GGL G 
Sbjct: 53  DAAAGLPSASAAAVSADFMSNL---SLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGD 109

Query: 123 TQA----LLQPQQPLPPPQ----------PGAAGG-SGQPRKCSS-RRNAWGNLSYADLI 166
            Q      L P  P PPP           P AAG  +GQPRK SS RRNAWGNLSYADLI
Sbjct: 110 FQGPEAGCLHPAPPQPPPPGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLI 169

Query: 167 TRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNE 226
           T+AIESS +KRLTLSQIYEWMV+ VPYFKDKGDSNSSAGWKNSIRHNLSLHS+F+RVQNE
Sbjct: 170 TKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIRVQNE 229

Query: 227 GTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSP- 285
           GTGKSSWW++NP+GGKSGK+PRRRA SMDN++K+ KSR RAAKKKA+LQ+  E A DSP 
Sbjct: 230 GTGKSSWWMLNPEGGKSGKSPRRRAASMDNNSKFAKSRSRAAKKKASLQSGQEGAGDSPG 289

Query: 286 SQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSP 345
           SQ SKWP SP S S+D+ D W+ FR RT+SNAST+SGRLSPIM  TE D++ + D  +  
Sbjct: 290 SQFSKWPASPGSHSNDDFDNWSTFRPRTSSNASTISGRLSPIM--TEQDDLGEGD--VHS 345

Query: 346 MLYSSSASLSPSVSKPCTVELPRLTDMAGTMNLNDGLTENLMDD---LLDNITLPPSQPS 402
           M+Y  SA+   S        LP L++++   N+     ENL+D+   L    +L  S  S
Sbjct: 346 MVYPPSAAKMAST-------LPSLSEISNPENM-----ENLLDNLNLLSSPTSLTVSTQS 393

Query: 403 PTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSLRQSPMQTIQENKPATFSSM 462
             G +MQ++  + +    + L SP+ ++    +G SS++ L Q P+QT+Q+NK +++  M
Sbjct: 394 SPGTMMQQTPCYSFAPPNTSLNSPSPNYQKYTYGQSSMSPLPQMPIQTLQDNK-SSYGGM 452

Query: 463 SHY--GNQTLQDLLTSDSLSHSDVMMTQSDPLMSQASTAVSAQNSRRNVMLRNDPMMSFA 520
           S Y      L++LLTSDS  H+D+ MT  DP ++Q ++ V  QN    +M  N  M ++ 
Sbjct: 453 SQYNCAPGLLKELLTSDSPPHNDI-MTPVDPGVAQPNSRVLGQNV---MMGPNSVMSTYG 508

Query: 521 AQPNQGSLVN-QNLLHHQHQTQGALGGSRALSNSVSNM-GLSESSSLGSAKHQQQSPVSQ 578
           +Q +   ++N  +  H  H  Q +    R L ++VS M   S  + L   K   Q P+  
Sbjct: 509 SQASHNKMMNPSSHTHPGHAQQTSAVNGRPLPHTVSTMPHTSGMNRLTQVKTPVQVPLPH 568

Query: 579 SMQTLSDSLSGSSLYSTSANLPVMG---HEKFPSDLDLDMFNGSLECDMESIIRSELMDA 635
            MQ    +L G S  S+      MG    EK PSDLD  MF   L+CDMESIIR++LMD 
Sbjct: 569 PMQ--MSALGGYSSVSSCNGYGRMGLLHQEKLPSDLD-GMFIERLDCDMESIIRNDLMDG 625

Query: 636 DGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
           D LDFNFD+++  Q        +F  + + ++ SWV G
Sbjct: 626 DTLDFNFDNVLPNQ--------SFPHSVKTTTHSWVSG 655


>gi|103472003 forkhead box O4 [Homo sapiens]
          Length = 505

 Score =  352 bits (904), Expect = 5e-97
 Identities = 243/646 (37%), Positives = 328/646 (50%), Gaps = 177/646 (27%)

Query: 16  VELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGS 75
           ++LDP+FEPQSRPRSCTWPL RPE+   P++P          PE E D            
Sbjct: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEP----------PEVEPD------------ 53

Query: 76  AMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ---QP 132
                       LG  +  E                         G ++ +L P    +P
Sbjct: 54  ------------LGEKVHTE-------------------------GRSEPILLPSRLPEP 76

Query: 133 LPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVP 192
              PQPG  G    PRK  SRRNAWGN SYA+LI++AIES+P+KRLTL+QIYEWMVR VP
Sbjct: 77  AGGPQPGILGAVTGPRKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVRTVP 136

Query: 193 YFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAV 252
           YFKDKGDSNSSAGWKNSIRHNLSLHS+F++V NE TGKSSWW++NP+GGKSGKAPRRRA 
Sbjct: 137 YFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKSSWWMLNPEGGKSGKAPRRRAA 196

Query: 253 SMDNSNKYTKSRGRAAKKKAALQTAPE--SADDSP-SQLSKWPGSPTSRSSDELDAWTDF 309
           SMD+S+K  + R +A KKK ++  AP   +   SP    +KW GSP SR+ +E D WT F
Sbjct: 197 SMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHFAKWSGSPCSRNREEADMWTTF 256

Query: 310 RSRTNSNASTVSGRLSPIMASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRL 369
           R R++SNAS+VS RLSP+   +   EV  ++ P S   Y+           P T      
Sbjct: 257 RPRSSSNASSVSTRLSPLRPES---EVLAEEIPASVSSYAGGV--------PPT------ 299

Query: 370 TDMAGTMNLNDGLTENLMDDLLDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSS 429
                   LN+GL      +LLD + L  S       L+ RS    ++ +  G+  P  +
Sbjct: 300 --------LNEGL------ELLDGLNLTSSH-----SLLSRSGLSGFSLQHPGVTGPLHT 340

Query: 430 FNSTVFGPSSLNSLRQSPMQTIQENKPATFSSMSHYGNQTLQDLLTSDS-LSHSDVMMTQ 488
           ++S++F P+      + P+   +      FSS     +Q L+ LLTSD+    +DV+MTQ
Sbjct: 341 YSSSLFSPA------EGPLSAGE----GCFSS-----SQALEALLTSDTPPPPADVLMTQ 385

Query: 489 SDPLMSQASTAVSAQNSRRNVMLRNDPMMSFAAQPNQGSLVNQNLLHHQHQTQGALGGSR 548
            DP++SQA T +                                           LGG  
Sbjct: 386 VDPILSQAPTLL------------------------------------------LLGGLP 403

Query: 549 ALSNSVSNMGLSESSSLGSAKHQQQSPVSQSMQTLS----DSLSGSSLYSTSANLPVM-- 602
           + S   + +GL         K  +    S  + TLS      +  S+    +   PV+  
Sbjct: 404 SSSKLATGVGL-------CPKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTP 456

Query: 603 -----GHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFNFD 643
                  ++ P DLDLDM+  +LECDM++II   + + +GLDFNF+
Sbjct: 457 PTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFNFE 502


>gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 492

 Score =  319 bits (818), Expect = 5e-87
 Identities = 204/455 (44%), Positives = 252/455 (55%), Gaps = 93/455 (20%)

Query: 9   APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68
           A L   +V++DP+F PQSRPRSCTWPL +P+L                         DED
Sbjct: 3   AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39

Query: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128
           G        A+G G                  +A G +D G      A  ++        
Sbjct: 40  G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65

Query: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188
                P P  GA  G  +  K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 66  -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119

Query: 189 RCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPR 248
           R VPYFKDKGDSNSSAGWKNSIRHNLSLH+RF+RVQNEGTGKSSWW++NP+GGK+GK PR
Sbjct: 120 RYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPR 179

Query: 249 RRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADD-SPS--------QLSKWPGSPTSRS 299
           RRAVSMDN  K+ + +G+A+KKK  LQ    S DD SPS          +KW  SP S +
Sbjct: 180 RRAVSMDNGAKFLRIKGKASKKK-QLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHA 238

Query: 300 SDELDAWTDFRSRTNSNASTVSGR-LSPIMASTELDEVQDDDAPLSPMLYSSSAS-LSPS 357
           SD+ +AW DFR           GR L    A  E DE  +  AP SP++Y S AS LSP+
Sbjct: 239 SDDYEAWADFRG---------GGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPA 289

Query: 358 VSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLDNI-----TLPPSQPSPT----GGLM 408
           +   C  ELPRL ++ G + L+ G    L + LLD         P  +P P     G L 
Sbjct: 290 LGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELA 349

Query: 409 QRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSL 443
              ++  Y  KG+   +P +   S +  P SL +L
Sbjct: 350 LAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTL 384



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)

Query: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641
           L D+L G   Y+ +A  P+    ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 410 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 467

Query: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
           FDS +              GA    +QSWVPG
Sbjct: 468 FDSALPPP------PPGLAGA-PPPNQSWVPG 492


>gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]
          Length = 562

 Score =  305 bits (781), Expect = 9e-83
 Identities = 188/395 (47%), Positives = 227/395 (57%), Gaps = 84/395 (21%)

Query: 9   APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68
           A L    V++DP+F PQSRP S TWPL +P+L                         DED
Sbjct: 180 AKLRAHHVDVDPDFAPQSRPHSSTWPLPQPDLAG-----------------------DED 216

Query: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128
           G        A+G G                  +A G +D G      A  ++        
Sbjct: 217 G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 242

Query: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188
                P P  GA  G  +  K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 243 -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 296

Query: 189 RCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPR 248
           R VPYFKDKGDSNSSAGWKNSIRHNLSLH+RF+RVQNEGTGKSSWW++NP+GGK+GK PR
Sbjct: 297 RYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPR 356

Query: 249 RRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADD-SPS--------QLSKWPGSPTSRS 299
           RRAVSMDN  K+ + +G+A+KKK  LQ    S DD SPS          +KW  SP S +
Sbjct: 357 RRAVSMDNGAKFLRIKGKASKKK-QLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHA 415

Query: 300 SDELDAWTDFRSRTNSNASTVSGR-LSPIMASTELDEVQDDDAPLSPMLYSSSAS-LSPS 357
           SD+ +AW DFR           GR L    A  E DE  +  AP SP++Y S AS LSP+
Sbjct: 416 SDDYEAWADFRG---------GGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPA 466

Query: 358 VSKPCTVELPRLTDMAGTMNLNDGLTENLMDDLLD 392
           +   C  ELPRL ++ G + L+ G    L + LLD
Sbjct: 467 LGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLD 501



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 26/56 (46%), Positives = 34/56 (60%), Gaps = 7/56 (12%)

Query: 618 GSLECDMESIIRSELMDADGLDFNFDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
           G+LECD+ESII ++ MD+D +DFNFDS +              GA    +QSWVPG
Sbjct: 514 GTLECDVESIILNDFMDSDEMDFNFDSALPPP------PPGLAGA-PPPNQSWVPG 562



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 26/81 (32%), Positives = 33/81 (40%), Gaps = 23/81 (28%)

Query: 74  GSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQ--- 130
           G  + + GGGG+G L  GLL          G QD   GP   AG L    ++++      
Sbjct: 482 GGPLGLHGGGGAG-LPEGLL---------DGAQD-AYGPRARAGTLECDVESIILNDFMD 530

Query: 131 ---------QPLPPPQPGAAG 142
                      LPPP PG AG
Sbjct: 531 SDEMDFNFDSALPPPPPGLAG 551


>gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 589

 Score =  145 bits (365), Expect = 2e-34
 Identities = 91/199 (45%), Positives = 106/199 (53%), Gaps = 63/199 (31%)

Query: 9   APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68
           A L   +V++DP+F PQSRPRSCTWPL +P+L                         DED
Sbjct: 3   AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39

Query: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128
           G        A+G G                  +A G +D G      A  ++        
Sbjct: 40  G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65

Query: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188
                P P  GA  G  +  K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 66  -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119

Query: 189 RCVPYFKDKGDSNSSAGWK 207
           R VPYFKDKGDSNSSAGWK
Sbjct: 120 RYVPYFKDKGDSNSSAGWK 138



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)

Query: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641
           L D+L G   Y+ +A  P+    ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 507 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 564

Query: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673
           FDS +              GA    +QSWVPG
Sbjct: 565 FDSALPPP------PPGLAGA-PPPNQSWVPG 589


>gi|208431824 forkhead box I3 [Homo sapiens]
          Length = 420

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 106/353 (30%), Positives = 157/353 (44%), Gaps = 57/353 (16%)

Query: 112 PATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCS--SRRNAWGNL----SYADL 165
           P  AAG      +   QP  P  P  P A  G G+    S  SR +    +    SY+ L
Sbjct: 95  PPPAAGTFGCSQRPFAQPA-PAAPASPAAPAGPGELGWLSMASREDLMKMVRPPYSYSAL 153

Query: 166 ITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV-- 223
           I  AI+S+P+++LTLS IY+++    P+++      S AGW+NSIRHNLSL+  F +V  
Sbjct: 154 IAMAIQSAPERKLTLSHIYQFVADSFPFYQ-----RSKAGWQNSIRHNLSLNDCFKKVPR 208

Query: 224 QNEGTGKSSWWIINPDGGK---SGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPES 280
             +  GK ++W ++P+  K   +G   R+R    + SN  T + G  +K +  L +   S
Sbjct: 209 DEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRRSEASNGSTVAAG-TSKSEEGLSSGLGS 267

Query: 281 A------DDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELD 334
                  ++SPS L +   SP                 T S AS+  G   P++ ST   
Sbjct: 268 GVGGKPEEESPSTLLRPSHSPEPPEG------------TKSTASSPGG---PMLTST--- 309

Query: 335 EVQDDDAPLSPMLYSSSASLSPSVSKPCTVELP--RLTDMAGTMNLNDGL--TENLMDDL 390
                  P     +SS +SLS S S      LP  R   + G    + G+    ++ +  
Sbjct: 310 -------PCLNTFFSSLSSLSVSSSVSTQRALPGSRHLGIQGAQLPSSGVFSPTSISEAS 362

Query: 391 LDNITLPPSQPSPTGGLMQRSSSFPYTTKGSGLGSPTSSFNSTVFGPSSLNSL 443
            D + L  S  + TG      S FP +T G G  SP   F+S     S +NSL
Sbjct: 363 ADTLQLSNSTSNSTGQRSSYYSPFPASTSG-GQSSP---FSSPFHNFSMVNSL 411


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 71/208 (34%), Positives = 98/208 (47%), Gaps = 33/208 (15%)

Query: 59  EEEDDEDDEDGGGRAGSAMAIGGG--------GGSGTLGSGLLLEDSARVL-AP--GGQD 107
           EE+++E+D+D GG  G  +A+            G   L      ED   +L AP  GG  
Sbjct: 28  EEDEEEEDDDEGGGGGPRLAVPAQRRRRRRSYAGEDELEDLEEEEDDDDILLAPPAGGSP 87

Query: 108 PGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLIT 167
              GPA AAG  +GG                G AGG G     +         SY  LIT
Sbjct: 88  APPGPAPAAGAGAGGGGG------------GGGAGGGGSAGSGAKNPLVKPPYSYIALIT 135

Query: 168 RAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNE- 226
            AI  SP KRLTLS+I E++    PY+++K        W+NSIRHNLSL+  F+++  E 
Sbjct: 136 MAILQSPKKRLTLSEICEFISGRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREP 190

Query: 227 -GTGKSSWWIINPDGG---KSGKAPRRR 250
              GK ++W ++P+      +G   RRR
Sbjct: 191 GNPGKGNYWTLDPESADMFDNGSFLRRR 218



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 23/74 (31%), Positives = 28/74 (37%), Gaps = 5/74 (6%)

Query: 70  GGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQP 129
           G    SA   GG G S    S   +E        GG    +  A AA   +   QA   P
Sbjct: 340 GPLPASAAKAGGPGASALARSPFSIESII-----GGSLGPAAAAAAAAQAAAAAQASPSP 394

Query: 130 QQPLPPPQPGAAGG 143
                PP PG++GG
Sbjct: 395 SPVAAPPAPGSSGG 408


>gi|195947376 forkhead box I2 [Homo sapiens]
          Length = 318

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 76/232 (32%), Positives = 105/232 (45%), Gaps = 41/232 (17%)

Query: 83  GGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAG 142
           G  G +G G LL  +A  L+P     G GPA      S G           P P  GA G
Sbjct: 30  GDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPYAAPSYGA----------PGPLLGAPG 79

Query: 143 G-----------SGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCV 191
           G           SGQ       R  +   SY+ LI  AI+S+P ++LTLSQIY+++    
Sbjct: 80  GLAGADLAWLSLSGQQELLRLVRPPY---SYSALIAMAIQSAPLRKLTLSQIYQYVAGNF 136

Query: 192 PYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIINP------DGGKS 243
           P++K      S AGW+NSIRHNLSL+  F +V    +  GK ++W ++P      D G  
Sbjct: 137 PFYK-----RSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNF 191

Query: 244 GKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSP 295
            +  +RRA     ++   +S  R+     A    P SA     Q S  P +P
Sbjct: 192 RRKRKRRA----EASAAVRSGARSVGGAEAPALEPPSAACLDLQASPSPSAP 239


>gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]
          Length = 457

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 80/291 (27%), Positives = 118/291 (40%), Gaps = 44/291 (15%)

Query: 75  SAMAIGGGGGSGTLGS-------GLLLEDSARVLAPG-GQDPGSGPATAAGGLSGGTQAL 126
           SA A+G G G+ + GS       G  +  S   ++PG G   G G +  A G++G    L
Sbjct: 47  SAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHL 106

Query: 127 LQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNL----------------------SYAD 164
                PL     GA GG       +S    +G                        SY  
Sbjct: 107 SPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYIS 166

Query: 165 LITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQ 224
           LIT AI+ SP+K LTLS+IY+W++   P+++      +   W+NSIRH+LS +  F++V 
Sbjct: 167 LITMAIQQSPNKMLTLSEIYQWIMDLFPFYR-----QNQQRWQNSIRHSLSFNDCFLKVP 221

Query: 225 N--EGTGKSSWWIINPDGG---KSGKAPRRRAVSMDNSNKYTKSRGRAA----KKKAALQ 275
              +  GK S+W ++PD G   ++G   RR+           K    AA    K  A  Q
Sbjct: 222 RSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQ 281

Query: 276 TAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSP 326
            +     ++    S+ P    S  S         R        T +  LSP
Sbjct: 282 ASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSP 332


>gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]
          Length = 463

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 80/291 (27%), Positives = 118/291 (40%), Gaps = 44/291 (15%)

Query: 75  SAMAIGGGGGSGTLGS-------GLLLEDSARVLAPG-GQDPGSGPATAAGGLSGGTQAL 126
           SA A+G G G+ + GS       G  +  S   ++PG G   G G +  A G++G    L
Sbjct: 53  SAAAMGSGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMGGSAGAAGVAGMGPHL 112

Query: 127 LQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNL----------------------SYAD 164
                PL     GA GG       +S    +G                        SY  
Sbjct: 113 SPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYIS 172

Query: 165 LITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQ 224
           LIT AI+ SP+K LTLS+IY+W++   P+++      +   W+NSIRH+LS +  F++V 
Sbjct: 173 LITMAIQQSPNKMLTLSEIYQWIMDLFPFYR-----QNQQRWQNSIRHSLSFNDCFLKVP 227

Query: 225 N--EGTGKSSWWIINPDGG---KSGKAPRRRAVSMDNSNKYTKSRGRAA----KKKAALQ 275
              +  GK S+W ++PD G   ++G   RR+           K    AA    K  A  Q
Sbjct: 228 RSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKAAAGAQ 287

Query: 276 TAPESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSP 326
            +     ++    S+ P    S  S         R        T +  LSP
Sbjct: 288 ASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALSP 338


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 86/302 (28%), Positives = 121/302 (40%), Gaps = 58/302 (19%)

Query: 5   PASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDE 64
           P  PAP  P      P  + Q  P       Q P+ + +PA    +     ++P      
Sbjct: 58  PPPPAPQPP------PPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPP 111

Query: 65  DDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQ 124
                   A       G GG G  G G         LAP G D     A A G    G  
Sbjct: 112 P-----AAALDGAKADGLGGKGEPGGG------PGELAPVGPDEKEKGAGAGGEEKKGA- 159

Query: 125 ALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGN---LSYADLITRAIESSPDKRLTLS 181
                         G  G  G+  K   ++N        SY  LI  AI  SP+KRLTL+
Sbjct: 160 --------------GEGGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLN 205

Query: 182 QIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQN--EGTGKSSWWIINPD 239
            IYE++++  PY+++     +  GW+NSIRHNLSL+  F++V    +  GK ++W+++P 
Sbjct: 206 GIYEFIMKNFPYYRE-----NKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPS 260

Query: 240 ------GGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPG 293
                 GG +GK  RR           T SR + A K+ A  T+        +    WP 
Sbjct: 261 SDDVFIGGTTGKLRRRS----------TTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPM 310

Query: 294 SP 295
           SP
Sbjct: 311 SP 312


>gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]
          Length = 667

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 88/310 (28%), Positives = 132/310 (42%), Gaps = 61/310 (19%)

Query: 101 LAPGGQDPGSGPATAAG------GLSGGTQALLQPQQPLPPPQPGAAG--GSGQPRKCSS 152
           + P    P S P T +       GL     +   P  PL PP  G+A   G G  R+ SS
Sbjct: 371 MRPSEPKPFSQPVTVSAADSFPDGLVHPPTSAAAPVTPLRPPGLGSASLHGGGPARRRSS 430

Query: 153 RR-------------------NAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPY 193
            +                   +     +YA LI +AI  +PD++LTL++IY W  R   Y
Sbjct: 431 DKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAY 490

Query: 194 FKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVS 253
           F+      ++A WKN++RHNLSLH  F+RV+N    K + W ++       +  +RR   
Sbjct: 491 FR-----RNTATWKNAVRHNLSLHKCFVRVENV---KGAVWTVD-----EREYQKRRPPK 537

Query: 254 MDNSNKYTKSR-------GRAAKKKAALQTAPESADDSPSQLSKWPGSPTS---RSSDEL 303
           M  S    K+           A  +AAL  +     +SP  L+  PGS +S    S D++
Sbjct: 538 MTGSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN--PGSASSLLPLSHDDV 595

Query: 304 DAWTDFRSRTNSNASTVSGRLSP------IMASTELDEVQDDDAPLSPMLYSSSASLSPS 357
            A  +      SN S+   RLSP      +    E  E ++D  P  P+   + ++  P 
Sbjct: 596 GAPVE---PLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSASGPP 652

Query: 358 VSKPCTVELP 367
             +    ELP
Sbjct: 653 EDRDLEEELP 662


>gi|50345831 forkhead box J3 [Homo sapiens]
          Length = 622

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 88/312 (28%), Positives = 134/312 (42%), Gaps = 38/312 (12%)

Query: 161 SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRF 220
           SYA LIT AI SSP K++TLS+IY+W+    PY+++ G     +GWKNSIRHNLSL+  F
Sbjct: 82  SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWKNSIRHNLSLNKCF 136

Query: 221 MRV--QNEGTGKSSWWII--NPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQT 276
           ++V    +  GK S+W I  NP        P++RA S++ ++        +   +  +  
Sbjct: 137 LKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERASTPYSIDSDSLGMECII-- 194

Query: 277 APESADDSPSQLSKWPGSPTSRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTELDEV 336
              S   SP+       +  +  + + D     RS  N++ S  S      +AS  L+ V
Sbjct: 195 ---SGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQS------LASVNLNSV 245

Query: 337 QD--DDAPLSPMLYSSSASLSPSV---------SKPCTVELPRLTDMAGTMN--LNDGLT 383
                  P++    S S SL+P            K          D++ +          
Sbjct: 246 GSVHSYTPVTSHPESVSQSLTPQQQPQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFE 305

Query: 384 ENLMDDLLDNITLPPSQPSPTGGLMQRS-----SSFPYTTKGSGLGSPTSSFNSTVFGPS 438
           ++L    L NI    SQ S T    Q S     S+ P++ + S   S  S  N+T     
Sbjct: 306 QSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSV 365

Query: 439 SLNSLRQSPMQT 450
           +  SL    M T
Sbjct: 366 AQVSLSHPQMHT 377


>gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]
          Length = 678

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 81/276 (29%), Positives = 122/276 (44%), Gaps = 55/276 (19%)

Query: 129 PQQPLPPPQPGAAG--GSGQPRKCSSRR-------------------NAWGNLSYADLIT 167
           P  PL PP  G+A   G G  R+ SS +                   +     +YA LI 
Sbjct: 416 PVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIR 475

Query: 168 RAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEG 227
           +AI  +PD++LTL++IY W  R   YF+      ++A WKN++RHNLSLH  F+RV+N  
Sbjct: 476 QAILETPDRQLTLNEIYNWFTRMFAYFR-----RNTATWKNAVRHNLSLHKCFVRVENV- 529

Query: 228 TGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSR-------GRAAKKKAALQTAPES 280
             K + W ++       +  +RR   M  S    K+           A  +AAL  +   
Sbjct: 530 --KGAVWTVD-----EREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFP 582

Query: 281 ADDSPSQLSKWPGSPTS---RSSDELDAWTDFRSRTNSNASTVSGRLSP------IMAST 331
             +SP  L+  PGS +S    S D++ A  +      SN S+   RLSP      +    
Sbjct: 583 LLNSPGMLN--PGSASSLLPLSHDDVGAPVE---PLPSNGSSSPPRLSPPQYSHQVQVKE 637

Query: 332 ELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELP 367
           E  E ++D  P  P+   + ++  P   +    ELP
Sbjct: 638 EPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELP 673


>gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]
          Length = 680

 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 81/276 (29%), Positives = 122/276 (44%), Gaps = 55/276 (19%)

Query: 129 PQQPLPPPQPGAAG--GSGQPRKCSSRR-------------------NAWGNLSYADLIT 167
           P  PL PP  G+A   G G  R+ SS +                   +     +YA LI 
Sbjct: 418 PVTPLRPPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIR 477

Query: 168 RAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEG 227
           +AI  +PD++LTL++IY W  R   YF+      ++A WKN++RHNLSLH  F+RV+N  
Sbjct: 478 QAILETPDRQLTLNEIYNWFTRMFAYFR-----RNTATWKNAVRHNLSLHKCFVRVENV- 531

Query: 228 TGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSR-------GRAAKKKAALQTAPES 280
             K + W ++       +  +RR   M  S    K+           A  +AAL  +   
Sbjct: 532 --KGAVWTVD-----EREYQKRRPPKMTGSPTLVKNMISGLSYGALNASYQAALAESSFP 584

Query: 281 ADDSPSQLSKWPGSPTS---RSSDELDAWTDFRSRTNSNASTVSGRLSP------IMAST 331
             +SP  L+  PGS +S    S D++ A  +      SN S+   RLSP      +    
Sbjct: 585 LLNSPGMLN--PGSASSLLPLSHDDVGAPVE---PLPSNGSSSPPRLSPPQYSHQVQVKE 639

Query: 332 ELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELP 367
           E  E ++D  P  P+   + ++  P   +    ELP
Sbjct: 640 EPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELP 675


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score = 84.3 bits (207), Expect = 3e-16
 Identities = 55/147 (37%), Positives = 75/147 (51%), Gaps = 15/147 (10%)

Query: 112 PATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSG---QPRKCSSRRNAWGNLSYADLITR 168
           P  AAG L          +   PPP PG  GG G    P K    +      SY  LI  
Sbjct: 8   PEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKP--PYSYVALIAM 65

Query: 169 AIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGT 228
           AI  S +KRLTLS IY++++   P+++      +  GW+NSIRHNLSL+  F++V  EG 
Sbjct: 66  AIRESAEKRLTLSGIYQYIIAKFPFYE-----KNKKGWQNSIRHNLSLNECFIKVPREGG 120

Query: 229 G--KSSWWIINP---DGGKSGKAPRRR 250
           G  K ++W ++P   D  + G   RRR
Sbjct: 121 GERKGNYWTLDPACEDMFEKGNYRRRR 147


>gi|24497501 forkhead box A1 [Homo sapiens]
          Length = 472

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 72/243 (29%), Positives = 109/243 (44%), Gaps = 18/243 (7%)

Query: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSAR--VLAPGGQDP-GSGPATAAGGLSGGTQA 125
           G G +  A+A   GG +G + S      +A    L+P G    G+  A +  GL     A
Sbjct: 74  GAGLSPGAVAGMPGGSAGAMNSMTAAGVTAMGTALSPSGMGAMGAQQAASMNGLGPYAAA 133

Query: 126 LLQPQQPLP--PPQPGA--AGGSGQPRKCS-SRRNAWGNLSYADLITRAIESSPDKRLTL 180
           +     P+   P   G   AGG G  +    S  +A    SY  LIT AI+ +P K LTL
Sbjct: 134 MNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTL 193

Query: 181 SQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQN--EGTGKSSWWIINP 238
           S+IY+W++   PY++      +   W+NSIRH+LS +  F++V    +  GK S+W ++P
Sbjct: 194 SEIYQWIMDLFPYYR-----QNQQRWQNSIRHSLSFNDCFVKVARSPDKPGKGSYWTLHP 248

Query: 239 DGG---KSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPESADDSPSQLSKWPGSP 295
           D G   ++G   RR+              G +    +  +  PES  D     +    SP
Sbjct: 249 DSGNMFENGCYLRRQKRFKCEKQPGAGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSP 308

Query: 296 TSR 298
             R
Sbjct: 309 LHR 311


>gi|8923842 forkhead box J2 [Homo sapiens]
          Length = 574

 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 31/177 (17%)

Query: 141 AGGSGQPRKCSS-----------------RRNAWGNLSYADLITRAIESSPDKRLTLSQI 183
           AG  G  RKCS                   ++     SYA LIT AI SSP K++TLS+I
Sbjct: 33  AGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEI 92

Query: 184 YEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRV--QNEGTGKSSWWIIN--PD 239
           Y W+    PY+K     N+  GWKNSIRHNLSL+  F +V    +  GK S+W I+  PD
Sbjct: 93  YRWICDNFPYYK-----NAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPD 147

Query: 240 GGKSGKAPRRRAVSMDNSNKYTKSR---GRAAKKKAAL--QTAPESADDSPSQLSKW 291
             +  + P    +S D+  +        G A   +A+L  +  P+ +  SP+ ++ +
Sbjct: 148 ISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASY 204


>gi|145309320 forkhead box Q1 [Homo sapiens]
          Length = 403

 Score = 83.2 bits (204), Expect = 7e-16
 Identities = 63/213 (29%), Positives = 96/213 (45%), Gaps = 43/213 (20%)

Query: 41  QASPAKPSGETAADSMIPEEEDDEDDEDGGGRAGSAMAIGG-----GGGSGTLGSGLLLE 95
           Q S  + +G + A S +    DD    DG   A S  A GG     G G  + G G   E
Sbjct: 16  QGSDLEGAGGSDAPSPLSAAGDDSLGSDGDCAANSPAAGGGARDTQGDGEQSAGGGPGAE 75

Query: 96  DS------ARVLAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRK 149
           ++      A V+A G +   +GP     G   G ++    ++P PP              
Sbjct: 76  EAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPP-------------- 121

Query: 150 CSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNS 209
                      SY  LI  AI  S   RLTL++I E+++   P+F+      S  GW+NS
Sbjct: 122 ----------YSYIALIAMAIRDSAGGRLTLAEINEYLMGKFPFFR-----GSYTGWRNS 166

Query: 210 IRHNLSLHSRFMRVQNEGT---GKSSWWIINPD 239
           +RHNLSL+  F++V  + +   GK ++W++NP+
Sbjct: 167 VRHNLSLNDCFVKVLRDPSRPWGKDNYWMLNPN 199


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 77/258 (29%), Positives = 108/258 (41%), Gaps = 65/258 (25%)

Query: 6   ASPAPLSPLEVELDP--------EFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMI 57
           +SPA LS  + ++D         E   +S PR+      R  L      P+ E  AD   
Sbjct: 15  SSPAALSEADADIDVVGGGSGGGELPARSGPRA-----PRDVLPHGHEPPAEEAEADLA- 68

Query: 58  PEEEDDEDDEDGGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAG 117
                ++++E GG   G   A+   G +   GS                 PG G A A G
Sbjct: 69  -----EDEEESGGCSDGEPRALASRGAAAAAGS-----------------PGPGAAAARG 106

Query: 118 GLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKR 177
               G            PP  GAA  S   +            SY  LIT AI  SP KR
Sbjct: 107 AAGPGPG----------PPSGGAATRSPLVKP---------PYSYIALITMAILQSPKKR 147

Query: 178 LTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNE--GTGKSSWWI 235
           LTLS+I E++    PY+++K        W+NSIRHNLSL+  F+++  E    GK ++W 
Sbjct: 148 LTLSEICEFISGRFPYYREK-----FPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWT 202

Query: 236 INPDGG---KSGKAPRRR 250
           ++P+      +G   RRR
Sbjct: 203 LDPESADMFDNGSFLRRR 220


>gi|24497506 forkhead box A3 [Homo sapiens]
          Length = 350

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 67/220 (30%), Positives = 101/220 (45%), Gaps = 29/220 (13%)

Query: 101 LAPGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRR---NAW 157
           LAP       GP     G+SGG+ +          P PG   G   P+    RR   +A 
Sbjct: 65  LAPPAPAAPLGPTFPGLGVSGGSSS-----SGYGAPGPGLVHGKEMPK--GYRRPLAHAK 117

Query: 158 GNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLH 217
              SY  LIT AI+ +P K LTLS+IY+W++   PY+++     +   W+NSIRH+LS +
Sbjct: 118 PPYSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE-----NQQRWQNSIRHSLSFN 172

Query: 218 SRFMRVQN--EGTGKSSWWIINPDGG---KSGKAPRRR-------AVSMDNSNKYTKSRG 265
             F++V    +  GK S+W ++P  G   ++G   RR+        V    S   T +R 
Sbjct: 173 DCFVKVARSPDKPGKGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGGSGAATTTRN 232

Query: 266 RAAKKKAALQTAPESADDSPSQLSKWPGSPTSRSSDELDA 305
                 AA  T P +   SP Q       P ++  +++ A
Sbjct: 233 GTG--SAASTTTPAATVTSPPQPPPPAPEPEAQGGEDVGA 270


>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
          Length = 490

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 45/116 (38%), Positives = 59/116 (50%), Gaps = 8/116 (6%)

Query: 127 LQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEW 186
           + P Q L    P +   S  P       N     S++ LI  AIE SP KRL +  IY W
Sbjct: 84  VSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNW 143

Query: 187 MVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNE---GTGKSSWWIINPD 239
           ++   PYF     +N+  GWKNS+RHNLSL+  F +V  E     GK S W I+P+
Sbjct: 144 ILEHFPYF-----ANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPE 194


>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
          Length = 468

 Score = 79.7 bits (195), Expect = 8e-15
 Identities = 45/116 (38%), Positives = 59/116 (50%), Gaps = 8/116 (6%)

Query: 127 LQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEW 186
           + P Q L    P +   S  P       N     S++ LI  AIE SP KRL +  IY W
Sbjct: 84  VSPVQDLDDDTPPSPAHSDMPYDARQNPNCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNW 143

Query: 187 MVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNE---GTGKSSWWIINPD 239
           ++   PYF     +N+  GWKNS+RHNLSL+  F +V  E     GK S W I+P+
Sbjct: 144 ILEHFPYF-----ANAPTGWKNSVRHNLSLNKCFKKVDKERSQSIGKGSLWCIDPE 194


>gi|18644886 forkhead box P1 isoform 1 [Homo sapiens]
          Length = 677

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 64/204 (31%), Positives = 101/204 (49%), Gaps = 21/204 (10%)

Query: 161 SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRF 220
           +YA LI +AI  SP+K+LTL++IY W  R   YF+      ++A WKN++RHNLSLH  F
Sbjct: 469 TYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFR-----RNAATWKNAVRHNLSLHKCF 523

Query: 221 MRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQTAPES 280
           +RV+N    K + W ++ +     + P++ + +         S        AALQ A  +
Sbjct: 524 VRVENV---KGAVWTVD-EVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQ-ASMA 578

Query: 281 ADDSPSQLSKWPGSPT-----SRSSDELDAWTDFRSRTNSNASTVSGRLSPIMASTEL-- 333
            +  P   +   G+PT     S   +EL+   +    TNSN S  S   SP+ A   +  
Sbjct: 579 ENSIPLYTTASMGNPTLGNLASAIREELNGAME---HTNSNESDSSPGRSPMQAVHPVHV 635

Query: 334 -DEVQDDDAPLSPMLYSSSASLSP 356
            +E  D +    P+   ++A+ SP
Sbjct: 636 KEEPLDPEEAEGPLSLVTTANHSP 659


>gi|4557595 forkhead box F2 [Homo sapiens]
          Length = 444

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 46/104 (44%), Positives = 62/104 (59%), Gaps = 9/104 (8%)

Query: 139 GAAGGSGQPRKCSS--RRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKD 196
           GA  GSG  +K SS  RR      SY  LI  AI+SSP KRLTLS+IY+++    P+F+ 
Sbjct: 80  GAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLTLSEIYQFLQARFPFFR- 138

Query: 197 KGDSNSSAGWKNSIRHNLSLHSRFMRVQN--EGTGKSSWWIINP 238
                +  GWKNS+RHNLSL+  F+++       GK  +W I+P
Sbjct: 139 ----GAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTIDP 178


>gi|110735445 forkhead box F1 [Homo sapiens]
          Length = 379

 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 52/139 (37%), Positives = 68/139 (48%), Gaps = 18/139 (12%)

Query: 102 APGGQDPGSGPATAAGGLSGGTQALLQPQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLS 161
           AP  Q P  G     GG  GG  A + P    P        G  +P K           S
Sbjct: 4   APEKQQPPHG---GGGGGGGGGGAAMDPASSGPSKAKKTNAGIRRPEKPP--------YS 52

Query: 162 YADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRFM 221
           Y  LI  AI+SSP KRLTLS+IY+++    P+F+      S  GWKNS+RHNLSL+  F+
Sbjct: 53  YIALIVMAIQSSPTKRLTLSEIYQFLQSRFPFFR-----GSYQGWKNSVRHNLSLNECFI 107

Query: 222 RVQN--EGTGKSSWWIINP 238
           ++       GK  +W I+P
Sbjct: 108 KLPKGLGRPGKGHYWTIDP 126


>gi|21618327 forkhead box I1 isoform a [Homo sapiens]
          Length = 378

 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 50/142 (35%), Positives = 76/142 (53%), Gaps = 11/142 (7%)

Query: 161 SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRF 220
           SY+ LI  AI  +PDKRLTLSQIY+++    P++     + S AGW+NSIRHNLSL+  F
Sbjct: 127 SYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFY-----NKSKAGWQNSIRHNLSLNDCF 181

Query: 221 MRV--QNEGTGKSSWWIINPDGGK---SGKAPRRRAVSMDNSNKYTKSRGRAAKKKAALQ 275
            +V    +  GK ++W ++P+  K   +G   R+R    D S+  T S      + +   
Sbjct: 182 KKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSS-TASLALEKTESSLPV 240

Query: 276 TAPESADDSPSQLSKWPGSPTS 297
            +P++ +         PG  TS
Sbjct: 241 DSPKTTEPQDILDGASPGGTTS 262


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 69/224 (30%), Positives = 107/224 (47%), Gaps = 32/224 (14%)

Query: 161 SYADLITRAIESSPDKRLTLSQIYEWMVRCVPYFKDKGDSNSSAGWKNSIRHNLSLHSRF 220
           +YA LI +AI  S D++LTL++IY W  R   YF+      ++A WKN++RHNLSLH  F
Sbjct: 508 TYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFR-----RNAATWKNAVRHNLSLHKCF 562

Query: 221 MRVQNEGTGKSSWWIINPDGGKSGKAPRRRAVSMDNSNKYTK----SRGRAAKKKAALQT 276
           +RV+N    K + W ++       +  +RR+  +  S    K    S G  A   A+LQ 
Sbjct: 563 VRVENV---KGAVWTVD-----EVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQA 614

Query: 277 APESADDSPSQLSKWPGSPTSRSSDELDA----WTDFRSRTNSNASTVSG-----RLSPI 327
           A   A+ S   LS  PG   + SS  L A            +SN ++  G      +  I
Sbjct: 615 A--LAESSLPLLSN-PGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSI 671

Query: 328 MASTELDEVQDDDAPLSPMLYSSSASLSPSVSKPCTVELPRLTD 371
               E    +D+D P+S +   ++A+ SP +     +E   L++
Sbjct: 672 HVKEEPVIAEDEDCPMSLV---TTANHSPELEDDREIEEEPLSE 712


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,757,221
Number of Sequences: 37866
Number of extensions: 1591929
Number of successful extensions: 13639
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 502
Number of HSP's that attempted gapping in prelim test: 10924
Number of HSP's gapped (non-prelim): 2475
length of query: 673
length of database: 18,247,518
effective HSP length: 109
effective length of query: 564
effective length of database: 14,120,124
effective search space: 7963749936
effective search space used: 7963749936
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.