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Search of human proteins with 42476169
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
(531 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42476169 Paf1, RNA polymerase II associated factor, homolog [... 1069 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 77 3e-14
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 77 4e-14
gi|21735415 centromere protein B [Homo sapiens] 72 1e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 70 5e-12
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 70 6e-12
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 68 2e-11
gi|55741677 SET domain containing 1A [Homo sapiens] 66 7e-11
gi|57634514 SPANX-N2 protein [Homo sapiens] 65 2e-10
gi|115529449 upstream binding transcription factor, RNA polymera... 62 1e-09
gi|115529451 upstream binding transcription factor, RNA polymera... 62 1e-09
gi|7657671 upstream binding transcription factor, RNA polymerase... 62 1e-09
gi|217330641 IWS1 homolog [Homo sapiens] 61 3e-09
gi|16445033 ACRC protein [Homo sapiens] 61 3e-09
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 60 5e-09
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 60 6e-09
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 60 6e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 60 6e-09
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 59 8e-09
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 59 8e-09
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 59 8e-09
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 59 1e-08
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 59 1e-08
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 59 1e-08
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 59 1e-08
>gi|42476169 Paf1, RNA polymerase II associated factor, homolog
[Homo sapiens]
Length = 531
Score = 1069 bits (2764), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQ 60
MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQ
Sbjct: 1 MAPTIQTQAQREDGHRPNSHRTLPERSGVVCRVKYCNSLPDIPFDPKFITYPFDQNRFVQ 60
Query: 61 YKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKR 120
YKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKR
Sbjct: 61 YKATSLEKQHKHDLLTEPDLGVTIDLINPDTYRIDPNVLLDPADEKLLEEEIQAPTSSKR 120
Query: 121 SQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIE 180
SQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIE
Sbjct: 121 SQQHAKVVPWMRKTEYISTEFNRYGISNEKPEVKIGVSVKQQFTEEEIYKDRDSQITAIE 180
Query: 181 KTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEM 240
KTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEM
Sbjct: 181 KTFEDAQKSISQHYSKPRVTPVEVMPVFPDFKMWINPCAQVIFDSDPAPKDTSGAAALEM 240
Query: 241 MSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVK 300
MSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVK
Sbjct: 241 MSQAMIRGMMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVK 300
Query: 301 NKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKE 360
NKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKE
Sbjct: 301 NKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKE 360
Query: 361 LEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER 420
LEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER
Sbjct: 361 LEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER 420
Query: 421 EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN 480
EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN
Sbjct: 421 EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN 480
Query: 481 DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD
Sbjct: 481 DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 77.4 bits (189), Expect = 3e-14
Identities = 49/205 (23%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEK--EAGGSDEEQEKGSSSEKEGSEDE 412
D ++K ++ + + N + E + + + + SDE ++ G+ S+ +G+ED+
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDD 513
Query: 413 HSGSESEREEGDRD-------EASDKSGSGE-------------------DESSEDEARA 446
S S S+ D + + +DKS SG+ +SS+ ++
Sbjct: 514 DSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSD 573
Query: 447 ARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSG 506
+ + SD+DS D +DSD D + SD+ S S+ S S S S+
Sbjct: 574 SNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS 633
Query: 507 SEHSAQEDGSEAAASDSSEADSDSD 531
S+ ++ D S++ +SDSS+ SD
Sbjct: 634 SDSDSKSDSSDSNSSDSSDNSDSSD 658
Score = 73.6 bits (179), Expect = 4e-13
Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 5/171 (2%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ +++ ++ + + + ++ + + S + + SS S D S+S
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS-- 675
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDND 481
D +SD S S + S D + ++ + SD+DS D +DS + + + + +D
Sbjct: 676 --DSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 482 SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S SN S S ++S S+ S D S+++ +SDSS++ + SD
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 784
Score = 72.0 bits (175), Expect = 1e-12
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 9/165 (5%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGS 434
+ + + + + SD + +SS S D S S+ + D +SD S S
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 435 GEDESSEDEARAARDKEEIFGSDADSED-DADSDDEDRGQAQGGSDNDSDSGSNGGGQRS 493
+ S D + ++ K + S++DS D D+ SD D + ++DS SN
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 494 RSHSRSASPFPSGSEHSAQEDGSEAA-------ASDSSE-ADSDS 530
S S +S S S+ S D S+++ +SDSS+ +DSDS
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDS 712
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/190 (24%), Positives = 81/190 (42%), Gaps = 14/190 (7%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D N ++ + ++ +P +E + ++ +S + S+D +
Sbjct: 444 DSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGN 503
Query: 415 GSESEREEGDRDEA------SDKSGSG----EDESSEDEARAARDKEEIFGSD----ADS 460
GS+S+ E D ++ SD +G+G +D D + D + SD +DS
Sbjct: 504 GSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563
Query: 461 EDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAA 520
D +DSD D + +DSDS + S S + S S S S S+ S +
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 521 SDSSEADSDS 530
SDSS+++SDS
Sbjct: 624 SDSSKSESDS 633
Score = 70.1 bits (170), Expect = 5e-12
Identities = 42/165 (25%), Positives = 76/165 (46%), Gaps = 7/165 (4%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + ++ ++ S + + +SS+ S D S+S + D +SD
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS--DSDSSNSSDS 826
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDAD----SDDEDRGQAQGGSDNDSDSGSN 487
S S + S + + ++ + GSD+DS + +D SD D + SD+ S SN
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSN 886
Query: 488 GGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S S S S S+ S D S+++ +SDSSE+ + SD
Sbjct: 887 ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Score = 69.7 bits (169), Expect = 6e-12
Identities = 39/170 (22%), Positives = 69/170 (40%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ + + + + + + + + SD SS + S+ + S+SE +
Sbjct: 573 DSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDND 481
D D SD S S +SS++ + +DS D +DS S +
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692
Query: 482 SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
SDS ++ S S S S S S +S D + +SDSS++ + SD
Sbjct: 693 SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD 742
Score = 68.9 bits (167), Expect = 1e-11
Identities = 42/180 (23%), Positives = 80/180 (44%), Gaps = 4/180 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + + + N + + ++ ++ S + E +SS+ S D +
Sbjct: 881 DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSN 940
Query: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDAD-SDDEDRGQ 473
S+S + D +SD S S + +S D + + + +DS D +D SD D
Sbjct: 941 SSDSS-DSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 474 AQGGSD-NDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
+ SD +DS S+ S+S +S S+ S D S+++ +SDSS++ + SD
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Score = 68.2 bits (165), Expect = 2e-11
Identities = 37/160 (23%), Positives = 69/160 (43%), Gaps = 3/160 (1%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER--EEGDRDEASDKS 432
+ + + ++ ++ S + + SS+ S D + S+S + D ++SD S
Sbjct: 984 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS 1043
Query: 433 GSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQ 491
S + S D + ++ + SD+ DS D +DS D S N SDS +
Sbjct: 1044 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSS 1103
Query: 492 RSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S ++ + + +SDSS++ + SD
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143
Score = 67.8 bits (164), Expect = 2e-11
Identities = 69/313 (22%), Positives = 121/313 (38%), Gaps = 70/313 (22%)
Query: 276 EEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKR 335
+E D+ +D +D I + N SK Y + EG +NE++
Sbjct: 280 QEGQDHGKEDDHDSSIGQ-------NSDSKEYYDP------EGKEDPHNEVDGDKTSKSE 326
Query: 336 RAKAGVQSGTNALLVVKHRDMNEKELEAQEAR-KAQLENHEPEEEEEEEMETEEKEAGGS 394
AG+ + + + +N +E + E R + E H + +++ +E + +G
Sbjct: 327 ENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNR 386
Query: 395 DEEQEKGSSSEKEGSEDEH-----------------------------------SGSESE 419
+ +E G +E + + +H +GS+S
Sbjct: 387 NITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSN 446
Query: 420 REEGDRDEASDKSGSGEDESSEDE------ARAARDKEEIFGSDADSEDDADSDDEDRGQ 473
+ D + DKS G+D +S DE A + D DA D D+ +
Sbjct: 447 SDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSD 506
Query: 474 AQGGSDNDSDS------------GSNGGGQRSRSHS---RSASPFPSGSEHSAQEDGSEA 518
++G D+DSDS G+NG +S S +S S S+ S D S++
Sbjct: 507 SKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDS 566
Query: 519 AASDSSEADSDSD 531
+ SDSS+++S SD
Sbjct: 567 SDSDSSDSNSSSD 579
Score = 66.6 bits (161), Expect = 5e-11
Identities = 43/181 (23%), Positives = 81/181 (44%), Gaps = 5/181 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D + + ++ ++ + N + + ++ + SD S S S D +
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 415 GSESEREEGDRDEASDKSGSGE--DESSEDEARAARDKEEIFGSDADSEDDAD-SDDEDR 471
S+S + D ++SD S S + +SS+ E+ ++ + SD++S D +D SD D
Sbjct: 601 SSDSS-DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDS 659
Query: 472 GQAQGGSD-NDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
+ SD +DS S+ S+S +S S S D S+++ SDSS++ S
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 531 D 531
+
Sbjct: 720 N 720
Score = 66.6 bits (161), Expect = 5e-11
Identities = 44/181 (24%), Positives = 80/181 (44%), Gaps = 7/181 (3%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGS-SSEKEGSEDEHSG 415
+ + ++ ++ + + + + + + + ++ SD S SS+ S D
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDS 607
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQA 474
S+S D + KS S + ES ++ + D + SD+ D+ D +DS +
Sbjct: 608 SDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSD 667
Query: 475 QGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEA----DSDS 530
S + SDS S+ S S S +S + SE S D S++ +SDSS++ SDS
Sbjct: 668 SSDSSDSSDSSSSSDSSNS-SDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 531 D 531
D
Sbjct: 727 D 727
Score = 66.6 bits (161), Expect = 5e-11
Identities = 39/164 (23%), Positives = 75/164 (45%), Gaps = 10/164 (6%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + + ++ + E+ SD + + SS ++S S + ++SD
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDS 671
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA----DSEDDADSDDEDRGQAQGGSDNDSDSGSN 487
S S + SS D + ++ + S++ DS D +DSD D + + +DSDS ++
Sbjct: 672 SDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNS 731
Query: 488 GGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S + S S+ S+ S D S++ SDSS + SD
Sbjct: 732 SDSSDSSNSSDSSD----SSDSSNSSDSSDS--SDSSNSSDSSD 769
Score = 66.6 bits (161), Expect = 5e-11
Identities = 39/177 (22%), Positives = 78/177 (44%), Gaps = 3/177 (1%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
+ + ++ ++ + N + ++ + S + + +SS+ S D + S
Sbjct: 706 DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSS 765
Query: 417 ESE--REEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQ 473
+S + D ++S+ S S + +S D + ++ + SD+ DS D +DSD +
Sbjct: 766 DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 474 AQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
+ SD+ S S+ S S S S + S+ S D S+++ S +S SDS
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDS 882
Score = 66.6 bits (161), Expect = 5e-11
Identities = 39/162 (24%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ + S + + +SS+ S D S+S D +++S+
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS-DSNDSSNS 791
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQ 491
S S + +S D + ++ + SD+DS + +DS + S + SDS + G
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 492 RSRSHSRSASPFPSGSEHSAQEDGS--EAAASDSSEADSDSD 531
S S +RS S S S S+ S + +SDS+E+ + SD
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893
Score = 66.6 bits (161), Expect = 5e-11
Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 2/170 (1%)
Query: 363 AQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE 422
+ + + N + ++ ++ S + SS+ S D S S +
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS-DS 1006
Query: 423 GDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDND 481
D ++SD S S + +S D + ++ + SD+ DS D +DS D S +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 482 SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
SDS + S S S+ S + + + + +SDSS++ SD
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116
Score = 66.2 bits (160), Expect = 7e-11
Identities = 37/153 (24%), Positives = 68/153 (44%), Gaps = 3/153 (1%)
Query: 379 EEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-GDRDEASDKSGSGED 437
+ + + ++ S + + +SS+ S D GS+S+ D +SD S S +
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 438 ESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS 497
+S D + ++ E + +DS D ++S D D + SD+ S S+ + S S
Sbjct: 874 SNSSDSSDSSDSNES--SNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931
Query: 498 RSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
S S S S S+ S ++ S+ +DS +
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSN 964
Score = 65.9 bits (159), Expect = 9e-11
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 17/183 (9%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D N+ + + + + + + ++ + ++ S + SS+ S D
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 415 GSES-EREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDD----E 469
S+S + + D SD S S + S D + ++ DS D +DS++
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS-----------DSSDSSDSNESSNSS 892
Query: 470 DRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADS 528
D + SD+DS SN S+S +S + S++S D S ++ +SDSS++ +
Sbjct: 893 DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSN 952
Query: 529 DSD 531
SD
Sbjct: 953 SSD 955
Score = 65.5 bits (158), Expect = 1e-10
Identities = 38/161 (23%), Positives = 73/161 (45%), Gaps = 4/161 (2%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + + ++ S + + +SS+ S D + S+S + D +SD
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSNSSDS 767
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQ 491
S S + S D + ++ + + +DS D ++S D S + SDS S+
Sbjct: 768 SDSSDSSDSSDSSNSSDSNDS--SNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 492 RSRSHSRSASPFPSGSEHSAQE-DGSEAAASDSSEADSDSD 531
S S S S S S S+ DGS++ +S+ S++ + SD
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Score = 65.5 bits (158), Expect = 1e-10
Identities = 38/162 (23%), Positives = 65/162 (40%), Gaps = 5/162 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + + S+ SS +GS+ + S D ++SD
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDS--GSNGG 489
S S + S D ++ + SD+ + D+DS D S N SDS SN
Sbjct: 874 SNSSDSSDSSDSNESSNSSDS---SDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ S S ++S S+ S D S ++ S +S SDS+
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSN 972
Score = 65.5 bits (158), Expect = 1e-10
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ E + + ++ ++ S + + SS+ S D + S+S + D ++SD
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS-DSSDSSDSSDS 1138
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S + + ++ + SD+ DS D +DS D S + SDS +
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1198
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + +SDS+E+ SD
Sbjct: 1199 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Score = 65.1 bits (157), Expect = 2e-10
Identities = 35/161 (21%), Positives = 66/161 (40%), Gaps = 1/161 (0%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ ++ S + + S SE + S+ + S+ D + SD
Sbjct: 597 DSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS 656
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S +S D + ++ + SD ++S D +DS D S + SDS S+
Sbjct: 657 SDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSS 716
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S+S + S + + +SDSS + SD
Sbjct: 717 DSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Score = 65.1 bits (157), Expect = 2e-10
Identities = 42/179 (23%), Positives = 69/179 (38%), Gaps = 4/179 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + + + N + + + E + + SS+ S S
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQA 474
S + + D +SD S S + +S D + ++ +DS D +DS D
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS--SDSSDSSDSSDSSDSSNSSD 784
Query: 475 QGGSDNDSDSG-SNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S N SDS S+ S S S S S S+ S D S ++ +SDSS + SD
Sbjct: 785 SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Score = 65.1 bits (157), Expect = 2e-10
Identities = 38/161 (23%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ + S + + SS+ S D + S S + D +SD
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS-DSSDSSNSSDS 803
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDAD-SDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + + + +DS D ++ SD D + GSD+DS + S+
Sbjct: 804 SNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSN 863
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S +S S+ S + S ++ S S SDSD
Sbjct: 864 SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Score = 65.1 bits (157), Expect = 2e-10
Identities = 41/163 (25%), Positives = 72/163 (44%), Gaps = 6/163 (3%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432
++ + + + + SD SS + S S + S+ + SD S
Sbjct: 762 SNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSS 821
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSD-NDSDSGSNG--G 489
S + +S D + ++ + +DS D +DSD +R + SD +DS SN
Sbjct: 822 NSSDSSNSSDSSDSSNSSDS--SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S S+ S S S S +S+ D S+++ +SDSS++ + SD
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSD 922
Score = 65.1 bits (157), Expect = 2e-10
Identities = 38/164 (23%), Positives = 66/164 (40%), Gaps = 5/164 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + +E ++ S + SS+ S D S+S + D +SD
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDS 1126
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA----DSEDDADSDDEDRGQAQGGSDNDSDSGSN 487
S S + S D + ++ + SD+ DS D +DS D S N SDS +
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186
Query: 488 GGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + +SDSS++ SD
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1230
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/163 (22%), Positives = 68/163 (41%), Gaps = 3/163 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESE--REEGDRDEAS 429
++ + + + ++ + S + + SS+ S D SES + D ++S
Sbjct: 1104 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSS 1163
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNG 488
D S S + S D + ++ + SD+ DS D +DS D S + SDS +
Sbjct: 1164 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1223
Query: 489 GGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S + S+ S + + +SDSS++ SDS+
Sbjct: 1224 DSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSN 1266
Score = 64.7 bits (156), Expect = 2e-10
Identities = 37/166 (22%), Positives = 71/166 (42%), Gaps = 15/166 (9%)
Query: 379 EEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDE 438
+ + ++ + ++ S E + S K S D +S S+ D ++S+ S S +
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS--DSSDSSNSSNSSDSS 669
Query: 439 SSEDEARAARDKEEIFGSD-------------ADSEDDADSDDEDRGQAQGGSDNDSDSG 485
S D + ++ + SD +DS D +DSD D + + +DSDS
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
++ S + S S+ S + + + + +SDSS++ SD
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSD 775
Score = 64.7 bits (156), Expect = 2e-10
Identities = 36/170 (21%), Positives = 70/170 (41%), Gaps = 2/170 (1%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ + + N + ++ + + + + S+ S D S+S
Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDND 481
D ++SD + S S D + ++ + +DS D ++S D + N
Sbjct: 877 S-DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNS 935
Query: 482 SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
SDS SN S S ++S + S+ S D S++ +SDSS++ + SD
Sbjct: 936 SDS-SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Score = 64.7 bits (156), Expect = 2e-10
Identities = 36/156 (23%), Positives = 63/156 (40%), Gaps = 1/156 (0%)
Query: 377 EEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGE 436
E + + SD SS+ + S S + S+ + + ++SD S S +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Query: 437 DESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRS 495
S D + ++ + SD+ DS D +DS + S N SDS + S
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 496 HSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S+ S + + + + +SDSS++ SD
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Score = 64.7 bits (156), Expect = 2e-10
Identities = 37/166 (22%), Positives = 66/166 (39%), Gaps = 6/166 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER--EEGDRDEAS 429
++ + + + ++ S + + SS+ S D S+S + D ++S
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSD----ADSEDDADSDDEDRGQAQGGSDNDSDSG 485
D S S + S D + ++ + SD +DS D +DS D S N SDS
Sbjct: 1068 DSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSS 1127
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ S S S+ S + + + +SDSS++ SD
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSD 1173
Score = 64.7 bits (156), Expect = 2e-10
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ ++ S + + SSE S D + S+S + D ++SD
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS-DSSDSSDSSDS 1108
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + SD+ DS + +DS D S + SDS +
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S++ S + + + +SDSS++ SD
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Score = 64.7 bits (156), Expect = 2e-10
Identities = 42/164 (25%), Positives = 75/164 (45%), Gaps = 5/164 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + E ++ + S + + SS+ S D S+S D ++SD
Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDS 1132
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDAD-SDDEDRGQAQGGSD-NDSDSGSNG 488
S S + +S D + ++ + SD+ DS D +D SD D + SD +DS S+
Sbjct: 1133 SDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192
Query: 489 GGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S S +S S+ S D S+++ +SDSS+++ SD
Sbjct: 1193 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236
Score = 63.5 bits (153), Expect = 4e-10
Identities = 39/186 (20%), Positives = 68/186 (36%), Gaps = 9/186 (4%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D +E + + + N + + + + S S S D +
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 415 GSESE--REEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSD-------ADSEDDAD 465
S+S + D ++SD S S + S D + ++ + SD +DS D +D
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 466 SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
S D S N SDS + S S S+ S + + + + +SDSS+
Sbjct: 1042 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSD 1101
Query: 526 ADSDSD 531
+ SD
Sbjct: 1102 SSDSSD 1107
Score = 63.5 bits (153), Expect = 4e-10
Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 7/165 (4%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + ++ ++ S + + +SS+ S D S+S + D ++SD
Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSDS 1120
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD----ADSEDDADSDDEDRGQAQGGSDNDSDSGSN 487
S S + S D + ++ SD +DS D +DS D S + SDS SN
Sbjct: 1121 SNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS-SN 1179
Query: 488 GGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S S +S S+ S D S+++ +SDSS++ SD
Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Score = 63.2 bits (152), Expect = 6e-10
Identities = 37/160 (23%), Positives = 59/160 (36%), Gaps = 1/160 (0%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432
++ + + + SD SS + S S S+ + D ++SD S
Sbjct: 660 SNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN-DSDSGSNGGGQ 491
S +S + + D S S+ SD D + SD+ DS S+
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDS 779
Query: 492 RSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ S S +S S+ S D S ++ S S SDSD
Sbjct: 780 SNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Score = 63.2 bits (152), Expect = 6e-10
Identities = 36/172 (20%), Positives = 70/172 (40%), Gaps = 2/172 (1%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ ++ + ++ + + + SD SS + S+ +S S+
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064
Query: 422 EG-DRDEASDKSGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSD 479
+ D ++SD S S + S D + ++ + SD +DS D +DS D S
Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1124
Query: 480 NDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ SDS + S + S S+ S + + + +SDSS++ SD
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176
Score = 63.2 bits (152), Expect = 6e-10
Identities = 42/159 (26%), Positives = 68/159 (42%), Gaps = 14/159 (8%)
Query: 386 TEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEAR 445
++ ++ S + + SS+ S D S+S + D ++SD S S E S D +
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDSSDSSESSDSSDSSN 1092
Query: 446 AARDKEEIFGSDA----DSEDDADSDDEDRGQAQGGSDNDSDSG--SNGGGQRSRSHSRS 499
++ + SD+ DS D +DS D S + SDS SN S S
Sbjct: 1093 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Query: 500 ASPFPSGSEHSAQEDGSEAA-------ASDSSEADSDSD 531
+S S+ S D S+++ +SDSS++ SD
Sbjct: 1153 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1191
Score = 63.2 bits (152), Expect = 6e-10
Identities = 37/161 (22%), Positives = 68/161 (42%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ E+ S + + SS+ S D S+S D ++SD
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSS-DSSDSSDS 1189
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + SD +DS D +DS D S + SDS +
Sbjct: 1190 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS 1249
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ ++ S + S ++ S++DSDS+
Sbjct: 1250 SDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290
Score = 62.8 bits (151), Expect = 8e-10
Identities = 41/162 (25%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG-SEDEHSGSESEREEGDRDEASDK 431
N + ++ + + +++ ++ SD SS + S D +S S+S+ + D ++SD
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDS---DSGSNG 488
S D S+ ++ + D + +DS D +DS + SD+DS S SN
Sbjct: 594 DSS--DSSNSSDSSDSSDSSD----SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647
Query: 489 GGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
S S +S + S+ S D S++++S S SDS
Sbjct: 648 SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689
Score = 62.8 bits (151), Expect = 8e-10
Identities = 37/166 (22%), Positives = 68/166 (40%), Gaps = 6/166 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + + SD SS + S+ S + S+ + SD
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDADSEDDAD--SDDEDRGQAQGGSDNDSDSGSNGG 489
S S S D + ++ E SD + D+ SD D + SD+ + S S+
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAA----ASDSSEADSDSD 531
S S+S +S + S+ S D S+++ +S+SS++ SD
Sbjct: 966 SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Score = 62.8 bits (151), Expect = 8e-10
Identities = 34/177 (19%), Positives = 64/177 (36%), Gaps = 5/177 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + + + N + + ++ + + S S + S
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQA 474
S + D E+SD S S S D + ++ + +DS D +DS D
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSD-----SSDSSDSSDSSDSSNSSD 1125
Query: 475 QGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S + SDS + S S S+ S + + + +SDSS++ + SD
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1182
Score = 62.8 bits (151), Expect = 8e-10
Identities = 36/161 (22%), Positives = 66/161 (40%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + ++ ++ S E + SS S D S+S + D ++SD
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-DSSDSSDSSDS 1117
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S S D + ++ + SD+ DS + +DS D S + SDS +
Sbjct: 1118 SDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDS 1177
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + +SDSS++ SD
Sbjct: 1178 SNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218
Score = 62.8 bits (151), Expect = 8e-10
Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 5/164 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESE--REEGDRDEAS 429
++ + + + ++ ++ S + + +SS+ S + S+S + D ++S
Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNG 488
D S S + +S D + ++ + SD +DS D +DS D S + SDS +
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 489 GGQRS--RSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
S S S +S + S+ S D S++ + + E+DS S
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Score = 62.8 bits (151), Expect = 8e-10
Identities = 39/160 (24%), Positives = 73/160 (45%), Gaps = 4/160 (2%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + E + ++ ++ S + + SS+ S D S+S + D ++SD
Sbjct: 1143 DSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS-DSSDSSDSSDS 1201
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDAD-SDDEDRGQAQGGSDNDSDSGSNGG 489
S S + S D + ++ + SD +DS + +D SD D + SD+ S S+
Sbjct: 1202 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDS 1261
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S S S S +G+ + + D S++ SDS+ + SD
Sbjct: 1262 TSDSNDESDSQSKSGNGNNNGSDSD-SDSEGSDSNHSTSD 1300
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/181 (22%), Positives = 73/181 (40%), Gaps = 9/181 (4%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + ++ ++ ++ + + + SD SS + S+ S
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS 677
Query: 415 GSESEREEG-DRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQ 473
S S+ D ++SD S S E S D + D + SD+ + + +DSD +
Sbjct: 678 SSSSDSSNSSDSSDSSDSSNSSESSDSSDSS----DSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 474 AQGGSD----NDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
+ S+ +DS SN S S ++S S+ S D S ++ S+ S SD
Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793
Query: 530 S 530
S
Sbjct: 794 S 794
Score = 62.4 bits (150), Expect = 1e-09
Identities = 42/189 (22%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + ++ + ++ + + + + ++ S + + SSS+ S D
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 415 GSESER--EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSD----ADSEDDAD--- 465
S+S E D ++SD S +SS + + SD +DS D +D
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 466 ----SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAAS 521
SD D + SD+ S S+ S S+ S S S S +S+ S ++
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 522 DSSEADSDS 530
S +DSDS
Sbjct: 812 SSDSSDSDS 820
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/183 (20%), Positives = 68/183 (37%), Gaps = 7/183 (3%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + + + + E ++ + S + + +S+ + S
Sbjct: 673 DSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732
Query: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-------DSEDDADSD 467
S D ++SD S S + S D + ++ + SD+ DS D ++S
Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792
Query: 468 DEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEAD 527
D S N SDS + S S + S S S S S+ S ++ S +D
Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSD 852
Query: 528 SDS 530
SDS
Sbjct: 853 SDS 855
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/161 (23%), Positives = 64/161 (39%), Gaps = 4/161 (2%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432
++ + + + + SD + SS + S S S D ++S+ S
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQR 492
S E +S D + ++ +DS D ++S D S + SDS S+
Sbjct: 922 DSSESSNSSDNSNSSDSSNS--SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 493 SRSHSRSASPFPSGSEHSAQEDGSEAAA--SDSSEADSDSD 531
S S S S S S S+ S ++ SDSS++ + SD
Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Score = 62.4 bits (150), Expect = 1e-09
Identities = 40/179 (22%), Positives = 76/179 (42%), Gaps = 4/179 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D N + ++ + + + + ++ S + + +SS+ S D +
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029
Query: 415 GSESE--REEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDR 471
S+S + D ++SD S S + +S D + ++ + SD+ DS D ++S D
Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 472 GQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
S + SDS S+ S S +S + S+ S D S+++ S +S SDS
Sbjct: 1090 SSNSSDSSDSSDS-SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDS 1147
Score = 62.4 bits (150), Expect = 1e-09
Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + ++ ++ S + + SS+ S D S+S E D ++S+
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS-ESSDSSDSSNS 1093
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + SD+ +S D +DS D S + SDS +
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDS 1153
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + + +SDSS++ SD
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1194
Score = 62.4 bits (150), Expect = 1e-09
Identities = 36/163 (22%), Positives = 67/163 (41%), Gaps = 3/163 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESE--REEGDRDEAS 429
++ + + + ++ + S + + SS+ S D SES + + ++S
Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNG 488
D S S + S D + ++ + SD+ DS D +DS D S SDS +
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157
Query: 489 GGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S ++ + + +SDSS++ SD
Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200
Score = 62.4 bits (150), Expect = 1e-09
Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 3/160 (1%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER--EEGDRDEASDKS 432
+ + + ++ ++ S + + +SS+ S D S+S + D E+SD S
Sbjct: 1095 DSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSS 1154
Query: 433 GSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQ 491
S + S D + ++ + S++ DS D +DS D S + SDS +
Sbjct: 1155 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1214
Query: 492 RSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + + +SDSS + SD
Sbjct: 1215 DSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSD 1254
Score = 62.0 bits (149), Expect = 1e-09
Identities = 35/161 (21%), Positives = 67/161 (41%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ ++ S + +SS+ S D S+S + D ++SD
Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSS-DSSDSSDSSDS 1051
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S S D + ++ + SD +DS + +DS D S + SDS +
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDS 1111
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S++ S + + + +SDSS++ SD
Sbjct: 1112 SDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSD 1152
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/162 (24%), Positives = 66/162 (40%), Gaps = 6/162 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEG-DRDEASD 430
++ + + E ++ ++ S + SS+ + S+ +S SE D +SD
Sbjct: 878 DSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD 937
Query: 431 KSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489
S S + S D + ++ S++ DS D SD D + SD+ S S+
Sbjct: 938 SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDS 997
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S S S S +S+ S SDSS + SD
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNS----SDSSNSSDSSD 1035
Score = 61.6 bits (148), Expect = 2e-09
Identities = 40/183 (21%), Positives = 80/183 (43%), Gaps = 6/183 (3%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D ++ + + + + + + ++ ++ S + + SS+ S D +
Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002
Query: 415 GSESE--REEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDR 471
S+S + D +SD S S + +S D + ++ + SD+ DS D ++S D
Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062
Query: 472 GQAQGGSDNDSDSGSNGGGQRS--RSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADS 528
S + SDS + S S S ++S S+ S D S+++ +SDSS++ +
Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Query: 529 DSD 531
SD
Sbjct: 1123 SSD 1125
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/165 (23%), Positives = 71/165 (43%), Gaps = 6/165 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + + ++ S E + SS+ S D S+S + D +SD
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDS 1183
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD----ADSEDDADSDDEDRGQAQGGSDNDSDSGSN 487
S S + S D + ++ + SD +DS D +DS D S + SDS +
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243
Query: 488 GGGQRSRSHSRSASPFPSGSEHSAQEDG-SEAAASDSSEADSDSD 531
S S S+ S S+ + + D S++ +++ +DSDSD
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSD 1288
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/155 (23%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
E+ + + + ++ ++ S + + +SS+ S D S+S + D ++SD
Sbjct: 1149 ESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSDS 1207
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + ++ +DS D +DS D S + SDS S+
Sbjct: 1208 SDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSND 1267
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
+ S S S+S + +GS+ + +GS++ S S +
Sbjct: 1268 E-SDSQSKSGNGNNNGSDSDSDSEGSDSNHSTSDD 1301
Score = 61.2 bits (147), Expect = 2e-09
Identities = 36/161 (22%), Positives = 64/161 (39%), Gaps = 2/161 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ ++ S + SS+ S D + S+S D +SD
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS-DSSNSSDS 1033
Query: 432 SGSGEDESSEDEARAARDKEEIFGSDA-DSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + SD+ DS D +DS D S SDS +
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S+ S + + + +SDSS++ SD
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD 1134
Score = 60.8 bits (146), Expect = 3e-09
Identities = 38/160 (23%), Positives = 70/160 (43%), Gaps = 3/160 (1%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + + ++ ++ S + SS+ S D + S+S + + ++SD
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS-DSSESSDSSDS 1156
Query: 432 SGSGEDESSEDEARAARDKEEIFGSD-ADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S S + S D + ++ + SD +DS D +DS D S + SDS S+
Sbjct: 1157 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS-SDSSD 1215
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
S S +S +E S D S+++ S +S SDS
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDS 1255
Score = 60.1 bits (144), Expect = 5e-09
Identities = 36/160 (22%), Positives = 71/160 (44%), Gaps = 3/160 (1%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESER--EEGDRDEASDKS 432
+ + + ++ ++ S + + +SS+ S + S+S + + ++SD S
Sbjct: 754 DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQR 492
S + +SS + + +DS D +DS D + SD+ + S S+
Sbjct: 814 DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873
Query: 493 SRSHSRSASPFPSGSEHSA-QEDGSEAAASDSSEADSDSD 531
S S S S + S +S+ D S ++ SDSS++ + SD
Sbjct: 874 SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Score = 59.7 bits (143), Expect = 6e-09
Identities = 39/166 (23%), Positives = 71/166 (42%), Gaps = 6/166 (3%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEG-DRDEASD 430
++ + + ++ + SD SS+ + S+ S + S+ + D +E+S+
Sbjct: 831 DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 431 KSGSGEDESSED----EARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGS 486
S S + +S D ++ + D + S SE SD+ + + SD+ S S
Sbjct: 891 SSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDS 950
Query: 487 NGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
+ S S S S S S S D S ++ +SDSS++ SD
Sbjct: 951 SNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSD 996
Score = 59.3 bits (142), Expect = 8e-09
Identities = 42/164 (25%), Positives = 68/164 (41%), Gaps = 11/164 (6%)
Query: 378 EEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGED 437
+ + ++ ++ S + + SS S D S+S D +SD S S +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS-DSSNSSDSSNSSDS 1033
Query: 438 ESSEDEARAARDKEEIFGSDA----DSEDDAD-SDDEDRGQAQGGSD----NDSDSGSNG 488
S D + ++ + SD+ DS D +D SD D + SD +DS SN
Sbjct: 1034 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 489 GGQRSRSHSRSASPFPSGSEHSAQEDGSEAA-ASDSSEADSDSD 531
S S +S S+ S D S ++ +SDSS++ SD
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/158 (23%), Positives = 61/158 (38%), Gaps = 20/158 (12%)
Query: 391 AGGSDEEQEKGSSSEKEGSEDEHSGSESE-----REEGDRDEASDKSGSGEDESSEDEAR 445
AG ++ G++ + + D +E +E+G + S+ S EDE E+ R
Sbjct: 146 AGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCR 205
Query: 446 AARDKEEIF-------GSDADSE------DDADSDDEDRGQAQGGSDNDSDSGSNGGGQR 492
+ EI ++E +DA D+ D + G+D D D GS
Sbjct: 206 NEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDE 265
Query: 493 SRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
+ + +S G E Q+ G E S +SDS
Sbjct: 266 EAGNGKDSSNNSKGQE--GQDHGKEDDHDSSIGQNSDS 301
Score = 40.4 bits (93), Expect = 0.004
Identities = 34/159 (21%), Positives = 63/159 (39%), Gaps = 11/159 (6%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432
N + +E+ + +E++ +S EG+ E + + + G + EA
Sbjct: 173 NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTK-EAEVTP 231
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQR 492
G+GED ++ + G+D D ED+ DDED G DS +N GQ
Sbjct: 232 GTGEDAGLDNSDGSPSGN----GADED-EDEGSGDDEDEEAGNG-----KDSSNNSKGQE 281
Query: 493 SRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ H + S ++S ++ + + + D D
Sbjct: 282 GQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGD 320
Score = 40.0 bits (92), Expect = 0.005
Identities = 42/176 (23%), Positives = 65/176 (36%), Gaps = 14/176 (7%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
NE QE ++ + E+E +E + G + E + +S E E +
Sbjct: 173 NEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPG 232
Query: 417 ESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQG 476
E D + S SG+G DE EDE + EE S + + +D G+
Sbjct: 233 TGEDAGLDNSDGSP-SGNGADE-DEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKE-- 288
Query: 477 GSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQE-DGSEAAASDSSEADSDSD 531
D+DS G N + P G E E DG + + S+ + A D
Sbjct: 289 -DDHDSSIGQNSDSKEYYD--------PEGKEDPHNEVDGDKTSKSEENSAGIPED 335
Score = 40.0 bits (92), Expect = 0.005
Identities = 35/150 (23%), Positives = 62/150 (41%), Gaps = 12/150 (8%)
Query: 373 NHEPEEEEEEEMETEEKEAG-GSD-EEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASD 430
N E+E+E + E++EAG G D KG + G ED+H S + D E D
Sbjct: 249 NGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIG--QNSDSKEYYD 306
Query: 431 KSGSGEDESSEDEARAARDKEEIFGSDADS-----EDDADSDDEDRGQAQGGSDNDSDSG 485
G + + D + ++ +E G D+ ED + + + + +S++
Sbjct: 307 PEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETH 366
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQEDG 515
+ G Q + S SG+ + +E G
Sbjct: 367 AVGKSQDKGIEIKGPS---SGNRNITKEVG 393
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 77.0 bits (188), Expect = 4e-14
Identities = 52/184 (28%), Positives = 80/184 (43%), Gaps = 18/184 (9%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEEEMETEE-KEAGGSDEEQ---EKGSSSEK-----EG 408
++E E E K + E P E E+E E EE K+ G ++EQ E+G E+ EG
Sbjct: 671 DEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEG 730
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARD-------KEEIFGSDADSE 461
E+EH E E EEGDR+E +K G G++E +E R+ KEE G + E
Sbjct: 731 GEEEHG--EGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGE 788
Query: 462 DDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAAS 521
++ D + + + +G + + G GG+ G + +G E
Sbjct: 789 EEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGE 848
Query: 522 DSSE 525
E
Sbjct: 849 GEEE 852
Score = 75.9 bits (185), Expect = 9e-14
Identities = 68/286 (23%), Positives = 109/286 (38%), Gaps = 40/286 (13%)
Query: 271 RKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRV 330
+KRD EE+ + + + +E + + +G EE EGD E E +
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE-------EGDR---EEEEEKE 752
Query: 331 RLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPE-EEEEEEMETEEK 389
K + G K +KE A + K + E + E EEEE E EEK
Sbjct: 753 GEGKEEGEGEEVEGERE----KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEK 808
Query: 390 EAGGS-------------DEEQEKGSSSEKEGSEDEHSGSESEREEGD-RDEASDKSGSG 435
E GG +EE+E+G E+EG +E G E E EEG+ + E + G G
Sbjct: 809 EEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEG-EGEEEEGEGKGEEEGEEGEG 867
Query: 436 EDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSG---------- 485
E+E E E ++ E G + + + + E G+ +G + + + G
Sbjct: 868 EEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
G G+ G E + +G E E + + +
Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/189 (28%), Positives = 78/189 (41%), Gaps = 31/189 (16%)
Query: 360 ELEAQEARKAQLENHEPEEE---EEEEMETEEKEAGGSDEE--------------QEKGS 402
E+E E + + E E EEE EEEE E EE+E G +EE +E+G
Sbjct: 813 EVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE 872
Query: 403 SSEKEGSEDEHSGSESEREEGDRDE-----ASDKSGSGEDESSEDEARAARDKEEIFGSD 457
E EG E+E G E EG+ +E ++ G GE E E E + + EE G
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 458 ADSEDDADSDD------EDRGQAQGGSDNDSDSG---SNGGGQRSRSHSRSASPFPSGSE 508
+ E + + +D E+ G+ +G + G G G+ G E
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 509 HSAQEDGSE 517
+E+G E
Sbjct: 993 EEGEEEGEE 1001
Score = 70.9 bits (172), Expect = 3e-12
Identities = 49/185 (26%), Positives = 78/185 (42%), Gaps = 13/185 (7%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG-- 415
E E E +E + + E E E E EEE E E +E G + +E+G E EG E+E G
Sbjct: 882 EGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEG 941
Query: 416 ----SESEREEGD---RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDD 468
E E EEG+ +E + G E E +E ++EE G + E + + ++
Sbjct: 942 EDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEE 1001
Query: 469 EDRGQAQG-GSDNDSDSGSNGG---GQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
E G+ +G G + + G G G+ G E + +G E +
Sbjct: 1002 EGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061
Query: 525 EADSD 529
E + +
Sbjct: 1062 EEEEE 1066
Score = 65.9 bits (159), Expect = 9e-11
Identities = 44/175 (25%), Positives = 70/175 (40%), Gaps = 10/175 (5%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGSEDEHSGS 416
E+E E E + E EEEE E E EE+ G G +EE E E EG +E G
Sbjct: 859 EEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Query: 417 ESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQG 476
EEG+ E + GE E + E ++ E G + + E + + + E G+ +G
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE-EG 977
Query: 477 GSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ + + G G + G E E+ E + E + + +
Sbjct: 978 EGEGEEEEGEGEGEEEEGEE--------EGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Score = 63.2 bits (152), Expect = 6e-10
Identities = 45/176 (25%), Positives = 72/176 (40%), Gaps = 8/176 (4%)
Query: 364 QEARKAQLENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE- 421
+E + + E E EEEE E E E+E G EE+E E+EG E E G E E E
Sbjct: 880 EEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEG 939
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKE-----EIFGSDADSEDDADSDDEDRGQAQG 476
EG+ E + GE E E+E ++E E + + E+ +E+ G+ +G
Sbjct: 940 EGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEG 999
Query: 477 GSDND-SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ + + G G + G +E+G E E + + +
Sbjct: 1000 EEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Score = 62.8 bits (151), Expect = 8e-10
Identities = 51/171 (29%), Positives = 77/171 (45%), Gaps = 15/171 (8%)
Query: 358 EKELEAQEAR-KAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG- 415
E E E +E K + E E E E EEE E E G + E+E+G E EG E+E G
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEG---EWEGEEEEGEGE 965
Query: 416 ----SESEREEGDRD-EASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
E E EEG+ + E + G GE+E E+E + EE + + E++ + + E
Sbjct: 966 GEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEV 1025
Query: 471 RGQAQGGSDNDSDSGSNGGGQRSR----SHSRSASPFPSGSEHSAQEDGSE 517
G+ +G + + + G G +R + +R E QE G E
Sbjct: 1026 EGE-EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEE 1075
Score = 60.8 bits (146), Expect = 3e-09
Identities = 39/131 (29%), Positives = 60/131 (45%), Gaps = 3/131 (2%)
Query: 358 EKELEAQEAR-KAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
E E E +E + + E E EE E E EE+E G EE+E E+EG +E
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 417 ESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQ- 475
E E EE E + GE E E+E ++ E G ++ + + ++E+ G+ Q
Sbjct: 1012 EGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQE 1071
Query: 476 -GGSDNDSDSG 485
G +N+ G
Sbjct: 1072 TGEEENERQDG 1082
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/116 (31%), Positives = 48/116 (41%), Gaps = 14/116 (12%)
Query: 364 QEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEG 423
+E + + E E EEE EEE E EE+ G +EE+E E EG E E G E E EE
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEE- 1041
Query: 424 DRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSD 479
GE+ E E R E + + E E+ + Q G +
Sbjct: 1042 ----------EGEEREKEGEGEENRRNRE---EEEEEEGKYQETGEEENERQDGEE 1084
Score = 49.3 bits (116), Expect = 9e-06
Identities = 35/105 (33%), Positives = 51/105 (48%), Gaps = 10/105 (9%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEE-----EMETEEKEAGGSDEE-QEKGSSSEKEGSED 411
E E E +E + + E EEEEE E+E EE E G +EE +E+G EKEG +
Sbjct: 994 EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053
Query: 412 EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGS 456
E+ + E EE E +GE+E+ + + +I GS
Sbjct: 1054 ENRRNREEEEE----EEGKYQETGEEENERQDGEEYKKVSKIKGS 1094
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/219 (19%), Positives = 79/219 (36%), Gaps = 53/219 (24%)
Query: 357 NEKELEAQEARKAQLEN--HEPEEEEEEEMETEEKEAGGSDEEQE--------------- 399
+++E+E E ++ ++ + EE+E E E K GG E+ E
Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEG 639
Query: 400 --------------KGSSSEKEGSEDEHSGSESEREEGDRDEA---SDKSGSGEDESSED 442
+G + +EGS + ERE+G++D+ ++ G GE E +E
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEK 699
Query: 443 EARAARDKE-------------------EIFGSDADSEDDADSDDEDRGQAQGGSDNDSD 483
E RD E E G + E + + D + + + G +
Sbjct: 700 EEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEG 759
Query: 484 SGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASD 522
G G+R + +G E +E+G + +
Sbjct: 760 EGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEE 798
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 72.4 bits (176), Expect = 1e-12
Identities = 46/132 (34%), Positives = 59/132 (44%), Gaps = 28/132 (21%)
Query: 378 EEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-----GDRDEASDKS 432
EEEEEE E EE+E G +EE+E+G E+EG E E G E E EE D +E D+
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465
Query: 433 GSGEDESSEDEARAARDKEEIFG-----------------------SDADSEDDADSDDE 469
S E +ED A+ + FG SD++ EDD + DDE
Sbjct: 466 SSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDE 525
Query: 470 DRGQAQGGSDND 481
D D D
Sbjct: 526 DEDDDDDEEDGD 537
Score = 53.5 bits (127), Expect = 5e-07
Identities = 43/161 (26%), Positives = 68/161 (42%), Gaps = 37/161 (22%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGS 434
E EEEEEEE E EE+E G +E E+EG E+E G E E
Sbjct: 404 EGEEEEEEEEEEEEEEGEGEEE--------EEEGEEEEEEGGEGEE-------------L 442
Query: 435 GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRG---QAQGGSDNDSDSGSNGGGQ 491
GE+E E+E D DS+++ + D+E +A+ + ++G + G
Sbjct: 443 GEEEEVEEEG------------DVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAY 490
Query: 492 RSRSHSRSAS-PFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
++ ++ + F G E S + E + E + D D
Sbjct: 491 GAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDD 531
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/158 (27%), Positives = 56/158 (35%), Gaps = 57/158 (36%)
Query: 338 KAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGG---- 393
+AG G NA + + E+E E +E E E E EEEEE EE+E GG
Sbjct: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEE----EEEEGEGEEEEEEGEEEEEEGGEGEE 441
Query: 394 --------------SDEEQEKGSSSEKEGSE----------------------------- 410
SDEE+E+ S EG E
Sbjct: 442 LGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTL 501
Query: 411 -----DEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
E S S+SE EE D +E + +DE DE
Sbjct: 502 HFLEGGEDSDSDSE-EEDDEEEDDEDEDDDDDEEDGDE 538
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 70.1 bits (170), Expect = 5e-12
Identities = 56/213 (26%), Positives = 97/213 (45%), Gaps = 28/213 (13%)
Query: 322 YYNELE---TRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEE 378
Y N+ E R R +RRAK+ G+ + + E++ + +R +Q + + E
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGL---------EVDRRASRSSQ--SSKEEV 174
Query: 379 EEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDE 438
EE E + GS +EQ + +E+EG E++ E E+ + DE D+ G E+E
Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 439 SSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQA-QGGSDN--------DSDSGSNGG 489
E+E ++EE + D + + +D + R +A GS++ S SG++G
Sbjct: 235 EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
Query: 490 GQRSRSHSRSASPFP-----SGSEHSAQEDGSE 517
++ + R+ P SGS S GSE
Sbjct: 295 DEKKKERKRARGISPIVFDRSGSSASESYAGSE 327
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/175 (21%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
N+ E R + P + E + E ++ A S + ++ +SE+ GS+ E
Sbjct: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQ 475
S S E+G+ E E+E E++ + EE DA+ +++ D D E+ + +
Sbjct: 188 SGSSDEQGNNTE-------NEEEGVEEDVEEDEEVEE----DAEEDEEVDEDGEEEEEEE 236
Query: 476 GGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
+ + + Q R + + + SE A + GSE+ + S S
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE--ASDSGSESVSFTDGSVRSGS 289
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/125 (31%), Positives = 56/125 (44%), Gaps = 8/125 (6%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKE-GSEDEHSGS 416
E++ E E E E EEEEEEE E EE+E DE +K ++ + SE SGS
Sbjct: 216 EEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 417 ESEREEGDRDEASDKSGS---GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQ 473
ES + S +SGS G DE ++ RA +F S ++ + E + +
Sbjct: 276 ESV----SFTDGSVRSGSGTDGSDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHE 331
Query: 474 AQGGS 478
S
Sbjct: 332 KLSSS 336
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/182 (20%), Positives = 80/182 (43%), Gaps = 19/182 (10%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDE 412
+++ EK + + + ++ P+ E +E + + + S SS++E + +E
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQ-------SSKEEVNSEE 178
Query: 413 H-----SGSESEREEGDRDEASDKSGSGED--ESSEDEARAARDKEEIFGSDADSEDDAD 465
+ +GS +E + +++ G ED E E E A D+E + + E++ +
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
Query: 466 SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
++E+ + + ++ D G +RS + SGSE + DGS + S +
Sbjct: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD-----SGSESVSFTDGSVRSGSGTDG 293
Query: 526 AD 527
+D
Sbjct: 294 SD 295
Score = 35.8 bits (81), Expect = 0.100
Identities = 38/199 (19%), Positives = 75/199 (37%), Gaps = 26/199 (13%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQE-----KGSSSEKEG 408
+D NEK+ +++ + + + + ++ + K S + KG S+ +
Sbjct: 37 QDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYK 96
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAAR-------------DKEEIFG 455
+E+ ++R + DR S S E ++ E R D E G
Sbjct: 97 NEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIG 156
Query: 456 SDAD--SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQE 513
+ D + + S E+ + GSD+++ S + Q + + + G E +E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE-----EGVEEDVEE 211
Query: 514 DGS-EAAASDSSEADSDSD 531
D E A + E D D +
Sbjct: 212 DEEVEEDAEEDEEVDEDGE 230
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 69.7 bits (169), Expect = 6e-12
Identities = 46/144 (31%), Positives = 73/144 (50%), Gaps = 16/144 (11%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D EK E +EA A+++N E +++E+EE + EEK G +++ EKG E++G ED++
Sbjct: 107 DATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKG---EEDGKEDKNG 163
Query: 415 GSESE--REEGDRDEASDKSGSGED--ESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
+ E +E+ D + D G+GED E EDE KE G ++ED + D+
Sbjct: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKET--GDGKENEDGKEKGDKK 221
Query: 471 RGQ-------AQGGSDNDSDSGSN 487
G+ + D D G N
Sbjct: 222 EGKDVKVKEDEKEREDGKEDEGGN 245
Score = 61.2 bits (147), Expect = 2e-09
Identities = 41/178 (23%), Positives = 78/178 (43%), Gaps = 14/178 (7%)
Query: 359 KELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSD---EEQEKGSSSEKEGSEDEHSG 415
K EA + K +E E E+ E E+KEA ++ EE+++ E + E +G
Sbjct: 86 KITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAG 145
Query: 416 SESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQ 473
E + E+G+ D DK+G+ GED +++ + D + G D + + + ++EDR +
Sbjct: 146 KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG-NGEDGKEKGEDEKEEEDRKE 204
Query: 474 AQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
G +N+ + + + + +EDG E + EA + +
Sbjct: 205 TGDGKENEDG--------KEKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKE 254
Score = 54.3 bits (129), Expect = 3e-07
Identities = 30/113 (26%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSS--EKEGS 409
K D EKE + ++ + + +E+ E+E E E+++ G +E E G +KEG
Sbjct: 166 KGEDAKEKE-DGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKEGK 224
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
+ + E ERE+G DE ++ +G+++ E ++++EI D E+
Sbjct: 225 DVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKKEE 277
Score = 52.4 bits (124), Expect = 1e-06
Identities = 53/245 (21%), Positives = 101/245 (41%), Gaps = 26/245 (10%)
Query: 268 LKKRKRDQEEEMDYAPDDVYDYK----IAREYNWNVKNKASKGYEENYFFIFREGDGVYY 323
+K + EE +D + V + K + +YN N KN +K E
Sbjct: 45 MKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAK---------ITEAPASEK 95
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHR--DMNEKELEAQEAR-KAQLENHEPEEEE 380
+E + + + G + VK+ D E E + E + +A E+ + + EE
Sbjct: 96 EIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE 155
Query: 381 EEEMETEEKEAGGSDEEQEKGSSSE--KEGSEDEHSGSESEREEGDRDEASD--KSGSGE 436
+ + + E G +E+E G E K ED E E+EE DR E D ++ G+
Sbjct: 156 DGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGK 215
Query: 437 DESSEDEARAA------RDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
++ + E + +++E+ + +E++A + ED + + G + D +G
Sbjct: 216 EKGDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEEDEIKEDDGKK 275
Query: 491 QRSRS 495
+ +S
Sbjct: 276 EEPQS 280
Score = 43.1 bits (100), Expect = 6e-04
Identities = 34/173 (19%), Positives = 63/173 (36%), Gaps = 8/173 (4%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
DM E+ ++ A+ + EE+ E A + + + +SEKE E +
Sbjct: 50 DMMEENIDTSAQAVAETKQEAVVEEDYNE------NAKNGEAKITEAPASEKEIVEVKEE 103
Query: 415 GSESEREEGD--RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRG 472
E E+G ++ + + + E++ EDE +K E D D + + D ++ G
Sbjct: 104 NIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNG 163
Query: 473 QAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
+G + + G G + E +E G D E
Sbjct: 164 NEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKE 216
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/216 (25%), Positives = 99/216 (45%), Gaps = 24/216 (11%)
Query: 322 YYNELE---TRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEE 378
Y N+ E R R +RRAK+ G+ + + E++ + +R +Q + + E
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGL---------EVDRRASRSSQ--SSKEEV 174
Query: 379 EEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDE 438
EE E + GS +EQ + +E+EG E++ E E+ + DE D+ G E+E
Sbjct: 175 NSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 439 SSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQA-QGGSDN--------DSDSGSNGG 489
E+E ++EE + D + + +D + R +A GS++ S SG++G
Sbjct: 235 EEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGS 294
Query: 490 GQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
++ + R+ P + S SE+ A +S+
Sbjct: 295 DEKKKERKRARGISPIVFDRSG-SSASESYADQTSK 329
Score = 48.9 bits (115), Expect = 1e-05
Identities = 38/175 (21%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
N+ E R + P + E + E ++ A S + ++ +SE+ GS+ E
Sbjct: 128 NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGS 187
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQ 475
S S E+G+ E E+E E++ + EE DA+ +++ D D E+ + +
Sbjct: 188 SGSSDEQGNNTE-------NEEEGVEEDVEEDEEVEE----DAEEDEEVDEDGEEEEEEE 236
Query: 476 GGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
+ + + Q R + + + SE A + GSE+ + S S
Sbjct: 237 EEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSE--ASDSGSESVSFTDGSVRSGS 289
Score = 43.9 bits (102), Expect = 4e-04
Identities = 37/182 (20%), Positives = 80/182 (43%), Gaps = 19/182 (10%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDE 412
+++ EK + + + ++ P+ E +E + + + S SS++E + +E
Sbjct: 126 YKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQ-------SSKEEVNSEE 178
Query: 413 H-----SGSESEREEGDRDEASDKSGSGED--ESSEDEARAARDKEEIFGSDADSEDDAD 465
+ +GS +E + +++ G ED E E E A D+E + + E++ +
Sbjct: 179 YGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEE 238
Query: 466 SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
++E+ + + ++ D G +RS + SGSE + DGS + S +
Sbjct: 239 EEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD-----SGSESVSFTDGSVRSGSGTDG 293
Query: 526 AD 527
+D
Sbjct: 294 SD 295
Score = 35.8 bits (81), Expect = 0.100
Identities = 38/199 (19%), Positives = 75/199 (37%), Gaps = 26/199 (13%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQE-----KGSSSEKEG 408
+D NEK+ +++ + + + + ++ + K S + KG S+ +
Sbjct: 37 QDKNEKKGSKRKSDRMESTDTKRQKPSVHSRQLVSKPLSSSVSNNKRIVSTKGKSATEYK 96
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAAR-------------DKEEIFG 455
+E+ ++R + DR S S E ++ E R D E G
Sbjct: 97 NEEYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIG 156
Query: 456 SDAD--SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQE 513
+ D + + S E+ + GSD+++ S + Q + + + G E +E
Sbjct: 157 LEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEE-----EGVEEDVEE 211
Query: 514 DGS-EAAASDSSEADSDSD 531
D E A + E D D +
Sbjct: 212 DEEVEEDAEEDEEVDEDGE 230
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 66.2 bits (160), Expect = 7e-11
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 12/182 (6%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSE 410
VK ++ +E ++E R P EE+E++ E +EKEAG K ++E +
Sbjct: 895 VKRKEPSEISEASEEKRPRP---STPAEEDEDDPE-QEKEAGEPGRPGTKPPKRDEERGK 950
Query: 411 DEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFG-----SDADSEDDAD 465
+ +S + + +EAS +S S +DE ++E D+EE ++ +D +
Sbjct: 951 TQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEE 1010
Query: 466 SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
SD + SD ++DS S+ S S S S+S S S S+ SE+++ D E
Sbjct: 1011 SDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS---SSSSSSSSSSSSESSSEDEEE 1067
Query: 526 AD 527
+
Sbjct: 1068 EE 1069
Score = 61.2 bits (147), Expect = 2e-09
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 25/175 (14%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D E+E EA E + +P + +EE +T+ K + E +S++ SE +
Sbjct: 923 DDPEQEKEAGEPGRP---GTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEE 979
Query: 415 GSESEREEGDRDEASDKS------GSGEDESSEDEARAARDKEEIFGSDADSEDDADSDD 468
E + E+ DR+EA D + GEDE S+ ++ + +D+D E+D+ SD
Sbjct: 980 DDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCS------LYADSDGENDSTSD- 1032
Query: 469 EDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDS 523
S++ S S S+ S S S S+S S SE +E+ A S S
Sbjct: 1033 ---------SESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSAS 1078
Score = 36.6 bits (83), Expect = 0.059
Identities = 32/102 (31%), Positives = 45/102 (44%), Gaps = 8/102 (7%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS-GSESER 420
EA+E + QL+ E EEE E E EE+E +E + SSS+ EG+ S S + R
Sbjct: 1345 EAEEPKPQQLQQQREEGEEEGEEEGEEEE----EESSDSSSSSDGEGALRRRSLRSHARR 1400
Query: 421 EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
+ E S ++ D I+ S DSED
Sbjct: 1401 RRPPPPPPPPPPRAYEPRSEFEQMTILYD---IWNSGLDSED 1439
>gi|57634514 SPANX-N2 protein [Homo sapiens]
Length = 180
Score = 65.1 bits (157), Expect = 2e-10
Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 6/128 (4%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
KH +N +LE ++R+ + + +EEE+E +++ E GS +E E SSE ED
Sbjct: 59 KHTKINSNQLEKDQSRENSI--NPVQEEEDEGLDSAE----GSSQEDEDLDSSEGSSQED 112
Query: 412 EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E S + D D S + S EDE + ++++ E++ + S++D D D +
Sbjct: 113 EDLDSSEGSSQEDEDLDSSEGSSQEDEDLDSSEGSSQEDEDLDPPEGSSQEDEDLDSSEG 172
Query: 472 GQAQGGSD 479
+GG D
Sbjct: 173 SSQEGGED 180
Score = 43.9 bits (102), Expect = 4e-04
Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 8/126 (6%)
Query: 400 KGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDAD 459
K +S++ E + + +EE DE D S E S EDE + + D D
Sbjct: 62 KINSNQLEKDQSRENSINPVQEE--EDEGLD---SAEGSSQEDEDLDSSEGSSQEDEDLD 116
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA 519
S + + +DED ++G S D D S+ G S P S+ D SE +
Sbjct: 117 SSEGSSQEDEDLDSSEGSSQEDEDLDSSEG---SSQEDEDLDPPEGSSQEDEDLDSSEGS 173
Query: 520 ASDSSE 525
+ + E
Sbjct: 174 SQEGGE 179
Score = 43.1 bits (100), Expect = 6e-04
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 12/121 (9%)
Query: 412 EHSGSESEREEGDRD-EASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
+H+ S + E D+ E S E++ D A + ++E D DS + + +DED
Sbjct: 59 KHTKINSNQLEKDQSRENSINPVQEEEDEGLDSAEGSSQEDE----DLDSSEGSSQEDED 114
Query: 471 RGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
++G S D D S+ G + S SE S+QED SS+ D D
Sbjct: 115 LDSSEGSSQEDEDLDSSEGSSQEDEDLDS-------SEGSSQEDEDLDPPEGSSQEDEDL 167
Query: 531 D 531
D
Sbjct: 168 D 168
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 62.4 bits (150), Expect = 1e-09
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 12/169 (7%)
Query: 302 KASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKEL 361
+ S+ +E+Y + E Y L+ V+ + +A + + K + M +
Sbjct: 569 RISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE----YISNKRKSMTKLRG 624
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ + L++ EE++EE E +E E +EE ++ S ++G + S SE E E
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESE 682
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
+GD +E D+ +++ EDE E GS + S DS D D
Sbjct: 683 DGDENEEDDEDEDDDEDDDEDE------DNESEGSSSSSSSSGDSSDSD 725
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Query: 402 SSSEKEGSEDEHSGSESEREEGDRD-EASDKSGSGEDESSEDEARAARDKEEIFGSDADS 460
S SE++ EDE E E EE D + ++S+ G + SSEDE+ + EE D D
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE---DDEDE 694
Query: 461 EDDADSDDEDRGQAQGGSDNDSDSGSN 487
+DD D D+++ +++G S + S SG +
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSSSSGDS 721
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/245 (22%), Positives = 90/245 (36%), Gaps = 26/245 (10%)
Query: 292 AREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVV 351
A E WN K +E +I + + E E LS+ RA + + +
Sbjct: 477 AMEMTWNNMEK-----KEKLMWIKKAAEDQKRYERE----LSEMRAPPAATNSSKKMKFQ 527
Query: 352 ---KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG 408
K MN + +QE NH P +E E+ + + S +E K + E++
Sbjct: 528 GEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQK 587
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEE--IFGSDADSEDDADS 466
H + +D A+ K S + R K S ++SE+D +
Sbjct: 588 QYKVHLDLWV-KSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEE 646
Query: 467 DDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEA 526
D++D + + D+++ S GG S S S S EDG E D E
Sbjct: 647 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES-----------EDGDENEEDDEDED 695
Query: 527 DSDSD 531
D + D
Sbjct: 696 DDEDD 700
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 62.4 bits (150), Expect = 1e-09
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 12/169 (7%)
Query: 302 KASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKEL 361
+ S+ +E+Y + E Y L+ V+ + +A + + K + M +
Sbjct: 569 RISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE----YISNKRKSMTKLRG 624
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ + L++ EE++EE E +E E +EE ++ S ++G + S SE E E
Sbjct: 625 PNPKSSRTTLQSKSESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESE 682
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
+GD +E D+ +++ EDE E GS + S DS D D
Sbjct: 683 DGDENEEDDEDEDDDEDDDEDE------DNESEGSSSSSSSSGDSSDSD 725
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Query: 402 SSSEKEGSEDEHSGSESEREEGDRD-EASDKSGSGEDESSEDEARAARDKEEIFGSDADS 460
S SE++ EDE E E EE D + ++S+ G + SSEDE+ + EE D D
Sbjct: 638 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE---DDEDE 694
Query: 461 EDDADSDDEDRGQAQGGSDNDSDSGSN 487
+DD D D+++ +++G S + S SG +
Sbjct: 695 DDDEDDDEDEDNESEGSSSSSSSSGDS 721
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/245 (22%), Positives = 90/245 (36%), Gaps = 26/245 (10%)
Query: 292 AREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVV 351
A E WN K +E +I + + E E LS+ RA + + +
Sbjct: 477 AMEMTWNNMEK-----KEKLMWIKKAAEDQKRYERE----LSEMRAPPAATNSSKKMKFQ 527
Query: 352 ---KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG 408
K MN + +QE NH P +E E+ + + S +E K + E++
Sbjct: 528 GEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQK 587
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEE--IFGSDADSEDDADS 466
H + +D A+ K S + R K S ++SE+D +
Sbjct: 588 QYKVHLDLWV-KSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEE 646
Query: 467 DDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEA 526
D++D + + D+++ S GG S S S S EDG E D E
Sbjct: 647 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES-----------EDGDENEEDDEDED 695
Query: 527 DSDSD 531
D + D
Sbjct: 696 DDEDD 700
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 62.4 bits (150), Expect = 1e-09
Identities = 42/169 (24%), Positives = 76/169 (44%), Gaps = 12/169 (7%)
Query: 302 KASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKEL 361
+ S+ +E+Y + E Y L+ V+ + +A + + K + M +
Sbjct: 606 RISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQDRAAYKE----YISNKRKSMTKLRG 661
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESERE 421
++ + L++ EE++EE E +E E +EE ++ S ++G + S SE E E
Sbjct: 662 PNPKSSRTTLQSKSESEEDDEEDEDDEDE--DEEEEDDENGDSSEDGGDSSESSSEDESE 719
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDED 470
+GD +E D+ +++ EDE E GS + S DS D D
Sbjct: 720 DGDENEEDDEDEDDDEDDDEDE------DNESEGSSSSSSSSGDSSDSD 762
Score = 61.6 bits (148), Expect = 2e-09
Identities = 31/87 (35%), Positives = 49/87 (56%), Gaps = 4/87 (4%)
Query: 402 SSSEKEGSEDEHSGSESEREEGDRD-EASDKSGSGEDESSEDEARAARDKEEIFGSDADS 460
S SE++ EDE E E EE D + ++S+ G + SSEDE+ + EE D D
Sbjct: 675 SESEEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEE---DDEDE 731
Query: 461 EDDADSDDEDRGQAQGGSDNDSDSGSN 487
+DD D D+++ +++G S + S SG +
Sbjct: 732 DDDEDDDEDEDNESEGSSSSSSSSGDS 758
Score = 46.6 bits (109), Expect = 6e-05
Identities = 56/245 (22%), Positives = 90/245 (36%), Gaps = 26/245 (10%)
Query: 292 AREYNWNVKNKASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVV 351
A E WN K +E +I + + E E LS+ RA + + +
Sbjct: 514 AMEMTWNNMEK-----KEKLMWIKKAAEDQKRYERE----LSEMRAPPAATNSSKKMKFQ 564
Query: 352 ---KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG 408
K MN + +QE NH P +E E+ + + S +E K + E++
Sbjct: 565 GEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQK 624
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEE--IFGSDADSEDDADS 466
H + +D A+ K S + R K S ++SE+D +
Sbjct: 625 QYKVHLDLWV-KSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEE 683
Query: 467 DDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEA 526
D++D + + D+++ S GG S S S S EDG E D E
Sbjct: 684 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDES-----------EDGDENEEDDEDED 732
Query: 527 DSDSD 531
D + D
Sbjct: 733 DDEDD 737
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 60.8 bits (146), Expect = 3e-09
Identities = 45/186 (24%), Positives = 86/186 (46%), Gaps = 35/186 (18%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+ + + E +E +K ++++ E E+E EEE + K A SD E E+ +S++K
Sbjct: 358 KKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKK------- 410
Query: 414 SGSESEREEGDRDEASDKSGSGE----DESSEDEARAARDK----EEIFGSDADSEDDAD 465
S S+ ++ D D SDKSG E +S E+ + DK +++FGSD++S ++ +
Sbjct: 411 SRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEE 470
Query: 466 SDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSE 525
+ D G + + +G N + +E+ E ++ +
Sbjct: 471 NLIADIFGESGDEEEEEFTGFN--------------------QEDLEEEKGETQVKEAED 510
Query: 526 ADSDSD 531
+DSD +
Sbjct: 511 SDSDDN 516
Score = 54.3 bits (129), Expect = 3e-07
Identities = 33/156 (21%), Positives = 70/156 (44%), Gaps = 4/156 (2%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
++ E E K + E+ + + E + +TE + ++ SD ++ + E+EH
Sbjct: 313 SDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHKK 372
Query: 416 SESEREEGDRDEASDKSGSGED---ESSEDEARAARDKEEIFGSDADSEDDADSDDEDRG 472
+ + +E +++ +K + SEDE +A+ K + DS+ DA SD +
Sbjct: 373 QKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKR 432
Query: 473 QAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSE 508
+ SD++ ++G +++ S SG+E
Sbjct: 433 EKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNE 468
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/182 (23%), Positives = 81/182 (44%), Gaps = 16/182 (8%)
Query: 362 EAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDE------HSG 415
E + R + E+ P++ + ETE+ E + S E +G + E HS
Sbjct: 293 ELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSD 352
Query: 416 SESEREE------GDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
S +R++ + + K S EDE +E + A+ K + +DSED+ + +
Sbjct: 353 SHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVL---SDSEDEEKASAK 409
Query: 470 DRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
D+DSD+ S+ G+R ++ + S S +G E S +++ + SE+ ++
Sbjct: 410 KSRVVSDADDSDSDAVSDKSGKREKTIA-SDSEEEAGKELSDKKNEEKDLFGSDSESGNE 468
Query: 530 SD 531
+
Sbjct: 469 EE 470
Score = 50.8 bits (120), Expect = 3e-06
Identities = 63/219 (28%), Positives = 92/219 (42%), Gaps = 47/219 (21%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEE---EEMETEEKEAGGSDEEQEK-----GSSSEK 406
++N + E++E + + + E EE E + E E+ GSD E E+ GS SE
Sbjct: 76 NLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSEN 135
Query: 407 E--------GSEDE----HSGSESEREEGDRDEASD-------KSGSGEDESSEDEARAA 447
E SE+E H S+SE EE + ASD K + ES E A
Sbjct: 136 EELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQA 195
Query: 448 RDKE-----EIFGSDADSED-------DADSDDEDRGQAQGGSDND------SDSGSNGG 489
D E + SD++SE+ D++S++ R QA + + SDS S
Sbjct: 196 SDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDP 255
Query: 490 GQRSRSHSRSAS-PFPSGSEHSAQEDGSEAAASDSSEAD 527
+ S S + P P S+ S ED ASDS +
Sbjct: 256 PRHQASDSENEELPKPRISD-SESEDPPRNQASDSENEE 293
Score = 49.7 bits (117), Expect = 7e-06
Identities = 48/193 (24%), Positives = 80/193 (41%), Gaps = 17/193 (8%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEE----KEAGGSDEEQEKGSSSEKE 407
+H+ + + E + R + E+ E + + + E+EE + + +EE K S+ E
Sbjct: 192 RHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSENEELPKPRISDSE 251
Query: 408 GSED--EHSGSESEREEGDRDEASDKSGS------GEDESSEDEARAARDKEEIFGSDAD 459
SED H S+SE EE + SD D +E+ + E G
Sbjct: 252 -SEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKG 310
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS-RSASPFPSGSEHSAQEDGSEA 518
D++++D R + + SD+DSD + G ++ S S S HS+ SE
Sbjct: 311 PASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSD---SEE 367
Query: 519 AASDSSEADSDSD 531
+ DSD D
Sbjct: 368 EEHKKQKMDSDED 380
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/195 (26%), Positives = 84/195 (43%), Gaps = 24/195 (12%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEK-EAGGSDEEQE----KGSSSEKE 407
H + + E + E+ E +++ + E+EE+ E SD E E GS SE E
Sbjct: 64 HHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESE 123
Query: 408 GSEDEHSGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSED--- 462
+ + GS+SE EE ASD G+ +S+ E + ++ SD+++ED
Sbjct: 124 ETR-KLPGSDSENEELLNGHASDSENEDVGKHPASDSE---IEELQKSPASDSETEDALK 179
Query: 463 ----DADSDDEDRGQAQGGSDND------SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQ 512
D++S++ R QA + + SDS S + S S S P + S
Sbjct: 180 PQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEEPPRHQASDSEN 239
Query: 513 EDGSEAAASDSSEAD 527
E+ + SDS D
Sbjct: 240 EELPKPRISDSESED 254
Score = 46.2 bits (108), Expect = 7e-05
Identities = 46/163 (28%), Positives = 73/163 (44%), Gaps = 29/163 (17%)
Query: 380 EEEEMETEEKEAGGS---DEEQEKGSSSEKEGSEDEHSGSE-------SEREEGDRDEAS 429
+ E ++ + GG+ +E++ GS E + +E +HSGS+ SE E DR++
Sbjct: 2 DSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNE-QHSGSDTGSVERHSENETSDREDGL 60
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDADSED-----DADSDDEDRGQAQGGSDNDSDS 484
K G +S DE + SD++SE+ D+DS+ E+R + + D
Sbjct: 61 PK-GHHVTDSENDEPL------NLNASDSESEELHRQKDSDSESEERAEPPASDSENEDV 113
Query: 485 GSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEAD 527
+G S S S P GS+ S E+ ASDS D
Sbjct: 114 NQHG----SDSESEETRKLP-GSD-SENEELLNGHASDSENED 150
Score = 44.3 bits (103), Expect = 3e-04
Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 11/168 (6%)
Query: 366 ARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKE-GSEDEHSGSESEREEGD 424
A Q E + E++ E GS E + +S++E G H ++SE +E
Sbjct: 16 ATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPL 75
Query: 425 RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED----DADSDDEDRGQAQGGSDN 480
ASD S S E +D + ++ E SD+++ED +DS+ E+ + GSD+
Sbjct: 76 NLNASD-SESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLP-GSDS 133
Query: 481 DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADS 528
+++ NG S + P + S E+ ++ ASDS D+
Sbjct: 134 ENEELLNGHASDSENEDVGKHP----ASDSEIEELQKSPASDSETEDA 177
Score = 42.7 bits (99), Expect = 8e-04
Identities = 39/171 (22%), Positives = 71/171 (41%), Gaps = 23/171 (13%)
Query: 379 EEEEEMETEEKEAG--------GSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASD 430
E E ET ++E G S+ ++ ++ SE+ H +S+ E +R E
Sbjct: 46 ERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAEPPA 105
Query: 431 KSGSGEDESSEDEARAARDKEEIFGSDADSED-----DADSDDEDRGQAQGGSDND---- 481
ED + + + ++ GSD+++E+ +DS++ED G+ SD++
Sbjct: 106 SDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGK-HPASDSEIEEL 164
Query: 482 -----SDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEAD 527
SDS + + S S S P + S E+ + SDS +
Sbjct: 165 QKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEE 215
Score = 32.3 bits (72), Expect = 1.1
Identities = 28/114 (24%), Positives = 49/114 (42%), Gaps = 5/114 (4%)
Query: 359 KELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSES 418
KEL ++ + L + E EEE + DEE+E+ + +E E+E ++
Sbjct: 446 KELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGFNQEDLEEEKGETQV 505
Query: 419 EREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDD----ADSDD 468
+ E + + K G D S+ E R K+ + G + D +D+DD
Sbjct: 506 KEAEDSDSDDNIKRGKHMDFLSDFEMMLQR-KKSMSGKRRRNRDGGTFISDADD 558
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 60.8 bits (146), Expect = 3e-09
Identities = 46/182 (25%), Positives = 79/182 (43%), Gaps = 13/182 (7%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D N +LE + +N + E ++ + E SD+ + +S+ + D++S
Sbjct: 130 DDNGNDLEVPD------DNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNS 183
Query: 415 GSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDAD--SDDEDRG 472
++ D + D S D++S+D + DK + DS DD+D D D
Sbjct: 184 DDSDVPDDNSDDSSDDNSDDSSDDNSDD-SDVPDDKSDDSDVPDDSSDDSDVPDDSSDDS 242
Query: 473 QAQGGSDNDS---DSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGS-EAAASDSSEADS 528
+A S +DS D S+ S S +P S + A +D S ++ ASD S DS
Sbjct: 243 EAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDS 302
Query: 529 DS 530
++
Sbjct: 303 EA 304
Score = 56.2 bits (134), Expect = 7e-08
Identities = 39/181 (21%), Positives = 75/181 (41%), Gaps = 4/181 (2%)
Query: 355 DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
D N + EA + E + ++ E + ++ D+ + S + S D++S
Sbjct: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDNS 209
Query: 415 G-SESEREEGDRDEASDKSGSGED--ESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
S+ ++ D + D S D + S D++ A D + + DS DD+++ D+
Sbjct: 210 DDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSS 269
Query: 472 GQAQGGSDNDSDS-GSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
++ D+ DS S+ S + S+ + + S D E + DS D +S
Sbjct: 270 DDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNS 329
Query: 531 D 531
D
Sbjct: 330 D 330
Score = 54.7 bits (130), Expect = 2e-07
Identities = 37/183 (20%), Positives = 72/183 (39%), Gaps = 7/183 (3%)
Query: 349 LVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG 408
L V + ++ E + ++ + ++ E + +++ EA + + +
Sbjct: 136 LEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDD 195
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGE--DESSEDEARAARDKEEIFGSDADSEDDADS 466
S D++S S+ D D DKS + D+SS+D D + D+++ DD+
Sbjct: 196 SSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDS-----DVPDDSSDDSEAPDDSSD 250
Query: 467 DDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEA 526
D E + S+ DS + S AS S ++ + ++ A D
Sbjct: 251 DSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD 310
Query: 527 DSD 529
DSD
Sbjct: 311 DSD 313
Score = 53.1 bits (126), Expect = 6e-07
Identities = 45/198 (22%), Positives = 80/198 (40%), Gaps = 23/198 (11%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEE--------------EMETEEKEAGGSDEEQEKGS 402
+++E E +KA+L ++E E + + + G+D E +
Sbjct: 83 SDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDN 142
Query: 403 SSEKEGSEDEHSGSESEREEGDRDEASDKSGSGE---DESSEDEARAARDKEEIFGSDAD 459
S + E +D SE+ + D EA D + D++S+D + ++ ++D
Sbjct: 143 SDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSD 202
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA 519
D +SDD D + + D S+ S S +P S + A +D S+ +
Sbjct: 203 DSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDS 262
Query: 520 -----ASDSSEA-DSDSD 531
+SD SEA D SD
Sbjct: 263 EAPDDSSDDSEAPDDSSD 280
Score = 53.1 bits (126), Expect = 6e-07
Identities = 41/165 (24%), Positives = 66/165 (40%), Gaps = 10/165 (6%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEA----SD 430
+ + +++ + E + D E +S + E +D SE+ + D EA SD
Sbjct: 125 DDDNDDDNGNDLEVPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSD 184
Query: 431 KSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
S +D S + + D + D+D DD SDD D + D S+
Sbjct: 185 DSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDD-KSDDSDVPDDSSDDSDVPDDSSDDSE 243
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAA-----ASDSSEADSDS 530
S S +P S + A +D S+ + +SD SEA DS
Sbjct: 244 APDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDS 288
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/170 (20%), Positives = 67/170 (39%), Gaps = 10/170 (5%)
Query: 372 ENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
++ + + ++ +++ + D E SS + E +D SE+ + D EA D
Sbjct: 218 KSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDD 277
Query: 432 SGSGEDES--SEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSD------ 483
S + S S D++ A+ D + + D DD+D ++ + DN D
Sbjct: 278 SSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVP 337
Query: 484 -SGSNGGGQRSRSHSRSASPFPSGSEHSAQED-GSEAAASDSSEADSDSD 531
GQ + + S+H + +D G + + S+ SD +
Sbjct: 338 AEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKPPSDPE 387
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/156 (18%), Positives = 63/156 (40%), Gaps = 4/156 (2%)
Query: 380 EEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSG----SG 435
++ ++E + D E SS + E +D SE+ + D EASD S +
Sbjct: 236 DDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEAS 295
Query: 436 EDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRS 495
+D S + EA + + D + D D+ D + +++ + G +
Sbjct: 296 DDSSDDSEAPDDKSDDSDVPEDKSDDSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELV 355
Query: 496 HSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
+ +A S+ + ++D E + S+ +++ +
Sbjct: 356 EAAAAVSQHDSSDDAGEQDLGENLSKPPSDPEANPE 391
Score = 42.0 bits (97), Expect = 0.001
Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 20/129 (15%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD-RDEASDKSG 433
+ E ++ ++E + D E SS + E S+D SE+ ++ D D DKS
Sbjct: 261 DSEAPDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSD 320
Query: 434 SGE--DESSED------------EARAARDKEEIFGSDA-----DSEDDADSDDEDRGQA 474
+ D++S+D E + A D+EE+ + A DS DDA D +
Sbjct: 321 DSDVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLS 380
Query: 475 QGGSDNDSD 483
+ SD +++
Sbjct: 381 KPPSDPEAN 389
Score = 32.0 bits (71), Expect = 1.4
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 14/123 (11%)
Query: 414 SGSESEREEGDRDEASDKSGSGEDESSED-EARAARDKEEIFGSDADSEDDADSD----D 468
S S+ E + +A + +DES E + A + I SD D++DD +D D
Sbjct: 81 SDSDEECHTHEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPD 140
Query: 469 EDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADS 528
++ ++ DN DS + S +P + + A +D S+ DS D
Sbjct: 141 DNSDDSEAPDDNSDDSEAPDDNSDD-----SEAPDDNSDDSEAPDDNSD----DSDVPDD 191
Query: 529 DSD 531
+SD
Sbjct: 192 NSD 194
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 60.1 bits (144), Expect = 5e-09
Identities = 48/197 (24%), Positives = 80/197 (40%), Gaps = 23/197 (11%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSS------SEK 406
H ++ E + R E + E+ + +++ +D+E E S SE
Sbjct: 73 HHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEA 132
Query: 407 EGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADS 466
EGSE HS + E+ R++ SD+S + ++S+DE RA E+ + D E ++
Sbjct: 133 EGSEKAHS----DDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNT 188
Query: 467 DDEDRGQ------------AQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQED 514
DDE+R Q + SD++ S+ ++ S P S E D
Sbjct: 189 DDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEE-QPQLSDEEKMQNSD 247
Query: 515 GSEAAASDSSEADSDSD 531
ASD SD +
Sbjct: 248 DERPQASDEEHRHSDDE 264
Score = 60.1 bits (144), Expect = 5e-09
Identities = 46/183 (25%), Positives = 79/183 (43%), Gaps = 4/183 (2%)
Query: 353 HR-DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEK-EGSE 410
HR D EA+ + KA ++ + E++ + +EK DEE+ +GS +K + S+
Sbjct: 121 HRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSD 180
Query: 411 DEHSGSESEREEGDRDEASDKSGSGEDE--SSEDEARAARDKEEIFGSDADSEDDADSDD 468
D+ ++ EE + ++ E+E +S+DE A D ++ + D E SD+
Sbjct: 181 DDEKMQNTDDEERPQLSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDE 240
Query: 469 EDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADS 528
E + SD +S S S SE + A + SEADS
Sbjct: 241 EKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADS 300
Query: 529 DSD 531
D++
Sbjct: 301 DTE 303
Score = 57.4 bits (137), Expect = 3e-08
Identities = 40/168 (23%), Positives = 63/168 (37%), Gaps = 3/168 (1%)
Query: 365 EARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD 424
EA + ++ + ++E + +G ++ E+G S + S E G +SE E
Sbjct: 15 EAERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQP--SNKELFGDDSEDEGAS 72
Query: 425 RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRG-QAQGGSDNDSD 483
SD D SE R+ + + D S +A +DDED G ++ GGS +
Sbjct: 73 HHSGSDNHSERSDNRSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEA 132
Query: 484 SGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
GS R S E D E A + +SD
Sbjct: 133 EGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEERAQGSDEDKLQNSD 180
Score = 57.0 bits (136), Expect = 4e-08
Identities = 40/137 (29%), Positives = 68/137 (49%), Gaps = 12/137 (8%)
Query: 357 NEKELEAQEARKAQLENHEP---EEEEEEEMETEEKEAGGSDEEQEKGSSSEK-EGSEDE 412
+++ + E KA ++ P + ++E++ +E++ SDEE+ + S E+ + S++E
Sbjct: 198 DDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEE 257
Query: 413 HSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFG-SDADSEDDADSDDEDR 471
H R D +E KS S SEDE + K I S+ADS+ + D+
Sbjct: 258 H------RHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGT 311
Query: 472 GQAQGGSDNDSDSGSNG 488
GG+D D SGS+G
Sbjct: 312 MDLFGGAD-DISSGSDG 327
Score = 56.6 bits (135), Expect = 5e-08
Identities = 52/205 (25%), Positives = 81/205 (39%), Gaps = 26/205 (12%)
Query: 343 SGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGS 402
SG+NA D +E+ Q + K +L + E+E + + SD E
Sbjct: 36 SGSNAS--GSESDQDERGDSGQPSNK-ELFGDDSEDEGASHHSGSDNHSERSDNRSEASE 92
Query: 403 SSEKEGSE----DEHSGSESEREEGDRDEASD------KSGSGEDESSEDEARAARDKEE 452
S+ E ++ D+HSGSE+ ++ D SD ++ E S+DE DK +
Sbjct: 93 RSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSD 152
Query: 453 IFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPS------G 506
+D E +SDDE+R Q GSD D S+ + +
Sbjct: 153 ----QSDDEKIQNSDDEERAQ---GSDEDKLQNSDDDEKMQNTDDEERPQLSDDERQQLS 205
Query: 507 SEHSAQEDGSEAAASDSSEADSDSD 531
E A D ASD+ + +SD
Sbjct: 206 EEEKANSDDERPVASDNDDEKQNSD 230
Score = 55.5 bits (132), Expect = 1e-07
Identities = 50/225 (22%), Positives = 106/225 (47%), Gaps = 16/225 (7%)
Query: 316 REGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHE 375
R G +++E E + K G + ++ K ++ +++E AQ + + +L+N +
Sbjct: 122 RSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNSDDEE-RAQGSDEDKLQNSD 180
Query: 376 PEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH---SGSESEREEGDRDEASDKS 432
+E+ + + E + SD+E+++ S EK S+DE S ++ E++ D +E S
Sbjct: 181 DDEKMQNTDDEERPQL--SDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLS 238
Query: 433 GSGEDESSEDEARAARDKEEIFGSDADSEDD-------ADSDDED-RGQAQGGSDNDSDS 484
+ ++S+DE A D+E D + +D +DS+DE R + + +DS++
Sbjct: 239 DEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEA 298
Query: 485 GSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S+ + + +S + F + S+ DG + + D +
Sbjct: 299 DSD--TEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDEN 341
Score = 50.1 bits (118), Expect = 5e-06
Identities = 31/83 (37%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Query: 449 DKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSE 508
D E++FGSDADSE A+ D D G ++ SGSN G S R S PS E
Sbjct: 3 DMEDLFGSDADSE--AERKDSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKE 60
Query: 509 HSAQEDGSEAAASDSSEADSDSD 531
+D + AS S +D+ S+
Sbjct: 61 LFG-DDSEDEGASHHSGSDNHSE 82
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 8/117 (6%)
Query: 352 KHRDMNEKELE-AQEARKAQLENHEPEEEEEEEMET---EEKEAGGSDEEQEK-GSSSEK 406
+ R M EK+ + A + + ++ EEE EE + + + GG EE+ + SS
Sbjct: 552 QQRRMREKQHQRGLSASYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSD 611
Query: 407 EGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDD 463
EGSE++ + + ++ DE + SG +ED+ +A + ++ SD + EDD
Sbjct: 612 EGSEEDKAQRLLKAKKLTSDEEGEPSGK---RKAEDDDKANKKHKKYVISDEEEEDD 665
Score = 37.4 bits (85), Expect = 0.034
Identities = 54/262 (20%), Positives = 101/262 (38%), Gaps = 38/262 (14%)
Query: 249 MMDEEGNQFVAYFLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKN------- 301
M+DEEG + L VE T++ R R EE + + AR W+ +
Sbjct: 403 MLDEEGRTRLK--LKVENTIRWRIRRDEEGNEIKESN------ARIVKWSDGSMSLHLGN 454
Query: 302 ------KASKGYEENYFFIFREGDGVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRD 355
KA + N+ FI R+G G+ + + +L+ R S T+ + + D
Sbjct: 455 EVFDVYKAPLQGDHNHLFI-RQGTGLQ-GQAVFKTKLTFR--PHSTDSATHRKMTLSLAD 510
Query: 356 MNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
K Q+ R + +PE + E ++ EE+ S + + ++ + S
Sbjct: 511 RCSK---TQKIRILPMAGRDPECQRTEMIKKEEERLRASIRRESQQRRMREKQHQRGLSA 567
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADS--------- 466
S E + D +E ++S S + + ++ I+ SD+D + D
Sbjct: 568 SYLEPDRYDEEEEGEESISLAAIKNRYKGGIREERARIYSSDSDEGSEEDKAQRLLKAKK 627
Query: 467 -DDEDRGQAQGGSDNDSDSGSN 487
++ G+ G + D +N
Sbjct: 628 LTSDEEGEPSGKRKAEDDDKAN 649
Score = 34.3 bits (77), Expect = 0.29
Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 3/95 (3%)
Query: 435 GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSR 494
G D SE E + D + SD+D E+ A + ++ DS SN
Sbjct: 9 GSDADSEAERK---DSDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDD 65
Query: 495 SHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S AS HS + D A+ S D+D
Sbjct: 66 SEDEGASHHSGSDNHSERSDNRSEASERSDHEDND 100
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
N +T + +R +K Q + L + N ++ +++A L + E E +EE
Sbjct: 300 NSRDTGLSQPRRDSKGDSQEDSKENLS-QEESQNVDGPSSESSQEANLSSQENSSESQEE 358
Query: 384 METEEKEAGGSD-----EEQEKGSSSEKEGSED-EHSGSESEREEGDRDEASDKSGSGED 437
+ +E + E+QE SSE++ S HS SES E+ D + + + S E
Sbjct: 359 VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 418
Query: 438 -ESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGS 486
ES EDE ++++ + S A+S+ + +ED +Q S + DS S
Sbjct: 419 PESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNS 468
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 37/220 (16%)
Query: 343 SGTNALLVVKHRDMNEKELEAQEARKAQLE-NHEPEEEEEEEMETEEKEAGGSDEEQEKG 401
SG + LL R + K ++E +++L+ N+ EE + + E G + +
Sbjct: 254 SGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 313
Query: 402 SSSEKEGSEDEHSGSESEREEGDRDEASDKSG-SGEDESSEDEARAA------------- 447
+E S++ S ES+ +G E+S ++ S ++ SSE +
Sbjct: 314 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTS 373
Query: 448 --RDKEEIFGSDADS------------EDDADSDDEDR---GQAQGGSDNDSDSGSNGGG 490
D+E+ S+ DS E+ ADS+ + + S D +S S G
Sbjct: 374 YVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGL 433
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
Q SHS SA E ++ED S++ S S+ DS+S
Sbjct: 434 Q---SHSSSAE--SQSEESHSEEDDSDSQDSSRSKEDSNS 468
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 33/229 (14%)
Query: 336 RAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEP----------EEEEEEEM- 384
R++ G +A + K N ++ Q++ +QL H EE++ E+
Sbjct: 224 RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 283
Query: 385 -------------ETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
E G + + +E S++ S ES+ +G E+S +
Sbjct: 284 DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQE 343
Query: 432 SG-SGEDESSEDE----ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDS-DSG 485
+ S ++ SSE + + + D + S + ++D+DS +ED S ++S +
Sbjct: 344 ANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQ 403
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQE---DGSEAAASDSSEADSDSD 531
++ S + S + P S+QE S +A S S E+ S+ D
Sbjct: 404 ADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEED 452
Score = 48.1 bits (113), Expect = 2e-05
Identities = 37/189 (19%), Positives = 71/189 (37%), Gaps = 9/189 (4%)
Query: 347 ALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEK 406
AL V ++++ ++ E + AQ E E E E +++ + S E
Sbjct: 16 ALPVTRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEG 75
Query: 407 EGSEDEH------SGSESEREEGDRDEASDKSGSGEDESSEDEARAA-RDKEEIFGSDAD 459
GS+D G +G D+ D+ SG+D +D++ +D++E G ++
Sbjct: 76 LGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQE--GGNSR 133
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAA 519
D DSDD + + + R + P G + + + + E
Sbjct: 134 LGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHW 193
Query: 520 ASDSSEADS 528
S+ +S
Sbjct: 194 VGGGSDGES 202
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 19/189 (10%)
Query: 359 KELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSE------------- 405
+EL+ ++ ++ E + +E E E E GGSD E G SE
Sbjct: 166 RELDNEDRVDSKPEGGDSTQESESE---EHWVGGGSDGESSHGDGSELDDEGMQSDDPES 222
Query: 406 ---KEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
+ G+ +S +E G+ E ++ SG + E +R K I D SE
Sbjct: 223 IRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSEL 282
Query: 463 DADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASD 522
D ++ E+ + N D+G + + S+ S+ S E S DG + +S
Sbjct: 283 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 342
Query: 523 SSEADSDSD 531
+ S +
Sbjct: 343 EANLSSQEN 351
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/146 (27%), Positives = 59/146 (40%), Gaps = 14/146 (9%)
Query: 395 DEEQEKGSSSEKEG----SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDK 450
D E+ KG ++ S + GS+ EE ++ SD + S E S+D R
Sbjct: 29 DSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLA 88
Query: 451 EEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSG------SNGGGQRSRSHSRSASPFP 504
S DD D D++D G G D DSG GG R S S
Sbjct: 89 GGFSRSTGKGGDDKDDDEDDSGDDTFGDD---DSGPGPKDRQEGGNSRLGSDEDSDDTIQ 145
Query: 505 SGSEHSAQ-EDGSEAAASDSSEADSD 529
+ E + Q +D ++ S+S E D++
Sbjct: 146 ASEESAPQGQDSAQDTTSESRELDNE 171
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQ----EKGSSSEKEGSEDE 412
++++ ++ E + +H E EE+ ++E E+ EE E +SS +EG +
Sbjct: 377 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 436
Query: 413 HSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
S +ES+ EE +E +D S+D +R+ D + ED
Sbjct: 437 SSSAESQSEESHSEE--------DDSDSQDSSRSKEDSNSTESKSSSEED 478
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/167 (23%), Positives = 70/167 (41%), Gaps = 8/167 (4%)
Query: 365 EARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEK----EGSEDEHSGSESER 420
++++ EN EE + + + E + QE S S++ E D + S
Sbjct: 316 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 375
Query: 421 EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN 480
E+ + ++S++ S S+ E+R + E S SE+ +S +++ +Q G +
Sbjct: 376 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS 435
Query: 481 DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEAD 527
S S + Q SHS S S +ED + + SSE D
Sbjct: 436 HSSSAES---QSEESHSEEDDSDSQDSSRS-KEDSNSTESKSSSEED 478
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 356 MNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
++ + E++E +A E+ E EE E+ E E S E + SSS + SE+ HS
Sbjct: 392 LSHSKSESRE-EQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS- 449
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKE-EIFGSDADSEDDADSDDEDRGQA 474
E + + D + + S S E +SS +E ++ E E D+ + D+D
Sbjct: 450 EEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDC 509
Query: 475 QGG 477
Q G
Sbjct: 510 QDG 512
Score = 40.4 bits (93), Expect = 0.004
Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Query: 379 EEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDE 438
+++++ E + + D++ G +EG +S S+ + D +AS++S +
Sbjct: 100 DDKDDDEDDSGDDTFGDDDSGPGPKDRQEGG---NSRLGSDEDSDDTIQASEESAPQGQD 156
Query: 439 SSEDEARAAR--DKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSH 496
S++D +R D E+ S + D + + GGSD +S G G +
Sbjct: 157 SAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD--GSELDDEG 214
Query: 497 SRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
+S P SE S S S +S+
Sbjct: 215 MQSDDPESIRSERGNSRMNSAGMKSKESGENSE 247
Score = 33.5 bits (75), Expect = 0.50
Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 19/161 (11%)
Query: 377 EEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGE 436
E+ ++ +EE G D Q+ S S + +ED +S+ E GD S +
Sbjct: 138 EDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDR---VDSKPEGGD---------STQ 185
Query: 437 DESSEDE-ARAARDKEEIFGSDADSEDDA-DSDDEDRGQAQGGSDNDSDSG--SNGGGQR 492
+ SE+ D E G ++ +D+ SDD + +++ G+ + +G S G+
Sbjct: 186 ESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGEN 245
Query: 493 SRSHSRSASPFPSGSEHSAQEDGSEAAAS---DSSEADSDS 530
S + S EH +++ ++ S D SE D ++
Sbjct: 246 SEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNN 286
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 59.7 bits (143), Expect = 6e-09
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
N +T + +R +K Q + L + N ++ +++A L + E E +EE
Sbjct: 284 NSRDTGLSQPRRDSKGDSQEDSKENLS-QEESQNVDGPSSESSQEANLSSQENSSESQEE 342
Query: 384 METEEKEAGGSD-----EEQEKGSSSEKEGSED-EHSGSESEREEGDRDEASDKSGSGED 437
+ +E + E+QE SSE++ S HS SES E+ D + + + S E
Sbjct: 343 VVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEES 402
Query: 438 -ESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGS 486
ES EDE ++++ + S A+S+ + +ED +Q S + DS S
Sbjct: 403 PESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNS 452
Score = 52.4 bits (124), Expect = 1e-06
Identities = 54/220 (24%), Positives = 92/220 (41%), Gaps = 37/220 (16%)
Query: 343 SGTNALLVVKHRDMNEKELEAQEARKAQLE-NHEPEEEEEEEMETEEKEAGGSDEEQEKG 401
SG + LL R + K ++E +++L+ N+ EE + + E G + +
Sbjct: 238 SGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDS 297
Query: 402 SSSEKEGSEDEHSGSESEREEGDRDEASDKSG-SGEDESSEDEARAA------------- 447
+E S++ S ES+ +G E+S ++ S ++ SSE +
Sbjct: 298 KGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTS 357
Query: 448 --RDKEEIFGSDADS------------EDDADSDDEDR---GQAQGGSDNDSDSGSNGGG 490
D+E+ S+ DS E+ ADS+ + + S D +S S G
Sbjct: 358 YVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGL 417
Query: 491 QRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDS 530
Q SHS SA E ++ED S++ S S+ DS+S
Sbjct: 418 Q---SHSSSAE--SQSEESHSEEDDSDSQDSSRSKEDSNS 452
Score = 48.5 bits (114), Expect = 1e-05
Identities = 48/229 (20%), Positives = 92/229 (40%), Gaps = 33/229 (14%)
Query: 336 RAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEP----------EEEEEEEM- 384
R++ G +A + K N ++ Q++ +QL H EE++ E+
Sbjct: 208 RSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELD 267
Query: 385 -------------ETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDK 431
E G + + +E S++ S ES+ +G E+S +
Sbjct: 268 DNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQE 327
Query: 432 SG-SGEDESSEDE----ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDS-DSG 485
+ S ++ SSE + + + D + S + ++D+DS +ED S ++S +
Sbjct: 328 ANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQ 387
Query: 486 SNGGGQRSRSHSRSASPFPSGSEHSAQE---DGSEAAASDSSEADSDSD 531
++ S + S + P S+QE S +A S S E+ S+ D
Sbjct: 388 ADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEED 436
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/189 (22%), Positives = 73/189 (38%), Gaps = 19/189 (10%)
Query: 359 KELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSE------------- 405
+EL+ ++ ++ E + +E E E E GGSD E G SE
Sbjct: 150 RELDNEDRVDSKPEGGDSTQESESE---EHWVGGGSDGESSHGDGSELDDEGMQSDDPES 206
Query: 406 ---KEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
+ G+ +S +E G+ E ++ SG + E +R K I D SE
Sbjct: 207 IRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSEL 266
Query: 463 DADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASD 522
D ++ E+ + N D+G + + S+ S+ S E S DG + +S
Sbjct: 267 DDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQ 326
Query: 523 SSEADSDSD 531
+ S +
Sbjct: 327 EANLSSQEN 335
Score = 45.4 bits (106), Expect = 1e-04
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQ----EKGSSSEKEGSEDE 412
++++ ++ E + +H E EE+ ++E E+ EE E +SS +EG +
Sbjct: 361 DQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSH 420
Query: 413 HSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSED 462
S +ES+ EE +E +D S+D +R+ D + ED
Sbjct: 421 SSSAESQSEESHSEE--------DDSDSQDSSRSKEDSNSTESKSSSEED 462
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/218 (22%), Positives = 86/218 (39%), Gaps = 37/218 (16%)
Query: 347 ALLVVKHRDMNEKELEAQEARKAQ-----LENHEPEE--EEEEEMETEEKE--------- 390
AL V ++++ ++ E + AQ L N +P + + EE + +++ +
Sbjct: 16 ALPVTRYQNNESEDSEEWKGHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGF 75
Query: 391 -----AGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDE-ASDKSGSGEDESSEDEA 444
GG D++ ++ S + +D+ +R+EG SD+ ++SE+ A
Sbjct: 76 SRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESA 135
Query: 445 RAARDKEEIFGSDA---DSEDDADSDDEDRGQAQ----------GGSDNDSDSGSNGGGQ 491
+D + S++ D+ED DS E Q GGSD +S G G +
Sbjct: 136 PQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGD--GSE 193
Query: 492 RSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
+S P SE S S S +S+
Sbjct: 194 LDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSE 231
Score = 45.1 bits (105), Expect = 2e-04
Identities = 39/167 (23%), Positives = 70/167 (41%), Gaps = 8/167 (4%)
Query: 365 EARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEK----EGSEDEHSGSESER 420
++++ EN EE + + + E + QE S S++ E D + S
Sbjct: 300 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYV 359
Query: 421 EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDN 480
E+ + ++S++ S S+ E+R + E S SE+ +S +++ +Q G +
Sbjct: 360 EDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQS 419
Query: 481 DSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEAD 527
S S + Q SHS S S +ED + + SSE D
Sbjct: 420 HSSSAES---QSEESHSEEDDSDSQDSSRS-KEDSNSTESKSSSEED 462
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/123 (27%), Positives = 56/123 (45%), Gaps = 3/123 (2%)
Query: 356 MNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG 415
++ + E++E +A E+ E EE E+ E E S E + SSS + SE+ HS
Sbjct: 376 LSHSKSESRE-EQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS- 433
Query: 416 SESEREEGDRDEASDKSGSGEDESSEDEARAARDKE-EIFGSDADSEDDADSDDEDRGQA 474
E + + D + + S S E +SS +E ++ E E D+ + D+D
Sbjct: 434 EEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDC 493
Query: 475 QGG 477
Q G
Sbjct: 494 QDG 496
Score = 33.5 bits (75), Expect = 0.50
Identities = 37/161 (22%), Positives = 69/161 (42%), Gaps = 19/161 (11%)
Query: 377 EEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGE 436
E+ ++ +EE G D Q+ S S + +ED +S+ E GD S +
Sbjct: 122 EDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDR---VDSKPEGGD---------STQ 169
Query: 437 DESSEDE-ARAARDKEEIFGSDADSEDDA-DSDDEDRGQAQGGSDNDSDSG--SNGGGQR 492
+ SE+ D E G ++ +D+ SDD + +++ G+ + +G S G+
Sbjct: 170 ESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGEN 229
Query: 493 SRSHSRSASPFPSGSEHSAQEDGSEAAAS---DSSEADSDS 530
S + S EH +++ ++ S D SE D ++
Sbjct: 230 SEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNN 270
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 59.7 bits (143), Expect = 6e-09
Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 4/94 (4%)
Query: 358 EKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSE 417
E++L + E E EEEEEEE E EE+E +EE+++ E+E E+E E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 418 SEREEGDRDEASDKSGSGEDESSEDEARAARDKE 451
E EEG+ +E ++ EDE E+E D E
Sbjct: 935 FEEEEGELEEEEEE----EDEEEEEELEEVEDLE 964
Score = 55.8 bits (133), Expect = 9e-08
Identities = 30/81 (37%), Positives = 45/81 (55%), Gaps = 4/81 (4%)
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKS 432
N EEEEEEE E EE+E +EE+E+ E+E E+E+ E E EE +E ++
Sbjct: 884 NSSDEEEEEEEEEEEEEE----EEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939
Query: 433 GSGEDESSEDEARAARDKEEI 453
G E+E E++ + EE+
Sbjct: 940 GELEEEEEEEDEEEEEELEEV 960
Score = 49.3 bits (116), Expect = 9e-06
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Query: 348 LLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSS--SE 405
L V+ +E+E E +E + + E E EE+ EEE E EE+ +EE+E+ E
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEE 937
Query: 406 KEGSEDEHSGSESEREEGDRDEASD 430
+EG +E E E EE + +E D
Sbjct: 938 EEGELEEEEEEEDEEEEEELEEVED 962
Score = 43.1 bits (100), Expect = 6e-04
Identities = 50/199 (25%), Positives = 84/199 (42%), Gaps = 21/199 (10%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSE 410
+ + E+E + +E + + E E EEEEEEE E E E+E G +EE+E+ E+E E
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Query: 411 D----EHSGSESEREEGDRDEASDKSGSGEDES-------SEDEARAARDKEEIFGSDAD 459
+ E + E EEG + ES E E + EE +
Sbjct: 959 EVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEER 1018
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGS--- 516
D A + + +QG + + +S + G + ++P P+ E EDGS
Sbjct: 1019 GADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP-PTLLEEET-EDGSDKV 1076
Query: 517 ----EAAASDSSEADSDSD 531
E A + E +++++
Sbjct: 1077 QPPPETPAEEEMETETEAE 1095
Score = 42.7 bits (99), Expect = 8e-04
Identities = 28/96 (29%), Positives = 48/96 (50%), Gaps = 11/96 (11%)
Query: 394 SDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEI 453
SDEE+E+ E+E E+E + E EE D +E + E+E E+E ++EE
Sbjct: 886 SDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE-----EEEEEEEEFEEEFEEEE- 939
Query: 454 FGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489
G + E++ D ++E+ + D + G+ GG
Sbjct: 940 -GELEEEEEEEDEEEEEELE----EVEDLEFGTAGG 970
Score = 40.0 bits (92), Expect = 0.005
Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 6/99 (6%)
Query: 381 EEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDR--DEASDKSGSGEDE 438
EE++ + +EE+E+ E+E E+E E E E+ + +E ++ E+E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 439 SSEDEARAARDKEEIFGSDADSEDDADS-DDEDRGQAQG 476
E+E ++EE D + E++ + +D + G A G
Sbjct: 935 FEEEEGELEEEEEE---EDEEEEEELEEVEDLEFGTAGG 970
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 255 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 304
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 305 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 361
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 362 AEEEVGEGTPQSSALTEG 379
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 240 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 293
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 294 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 341
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 342 NHLLVVPESRFDRDSGES 359
Score = 49.7 bits (117), Expect = 7e-06
Identities = 59/283 (20%), Positives = 111/283 (39%), Gaps = 33/283 (11%)
Query: 264 VEETLKKRKRDQEEEMDYAPDDVYDYK---IAREYNWNVKNKASK-GYEENYFFIFREGD 319
V+E +R++ EE D A + K +ARE++ +++ + + RE
Sbjct: 114 VKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 173
Query: 320 GVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEE 379
+ E R +RR + + +A HR M E + + KA + P
Sbjct: 174 KEQREQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRP 226
Query: 380 EEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDES 439
E E + +E+ E E++ D S+SER+ + +S +SGSG +E
Sbjct: 227 PRERFELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 281
Query: 440 SEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS-- 497
E+E ++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 282 EEEE----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 337
Query: 498 -----------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 338 RENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 380
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 151 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 209
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 210 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 264
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 265 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 324
Query: 525 EADSDSD 531
E S+ +
Sbjct: 325 EEVSEEE 331
Score = 33.9 bits (76), Expect = 0.38
Identities = 36/211 (17%), Positives = 66/211 (31%), Gaps = 32/211 (15%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDE 412
H +EK E + + + HE + EE + +E + S +E E
Sbjct: 98 HHRKDEKRKEKWKHARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLE 157
Query: 413 HSGSESEREEGDRDEASDKSGSGEDESSEDEARAARD-KEEIFGSDADSEDD-------- 463
+ ERE R++ ++ E E +E R R+ + E+ +D
Sbjct: 158 QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKAS 217
Query: 464 -----------------------ADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSA 500
+ E+R D + S + S S
Sbjct: 218 HWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 277
Query: 501 SPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S E +E+GS + S+ E + + +
Sbjct: 278 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 308
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 314
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 371
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 372 AEEEVGEGTPQSSALTEG 389
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 250 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 303
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 304 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 351
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 352 NHLLVVPESRFDRDSGES 369
Score = 49.7 bits (117), Expect = 7e-06
Identities = 59/283 (20%), Positives = 111/283 (39%), Gaps = 33/283 (11%)
Query: 264 VEETLKKRKRDQEEEMDYAPDDVYDYK---IAREYNWNVKNKASK-GYEENYFFIFREGD 319
V+E +R++ EE D A + K +ARE++ +++ + + RE
Sbjct: 124 VKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQ 183
Query: 320 GVYYNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEE 379
+ E R +RR + + +A HR M E + + KA + P
Sbjct: 184 KEQREQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRP 236
Query: 380 EEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDES 439
E E + +E+ E E++ D S+SER+ + +S +SGSG +E
Sbjct: 237 PRERFELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 440 SEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS-- 497
E+E ++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 292 EEEE----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347
Query: 498 -----------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 348 RENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 390
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 161 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 219
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 220 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 274
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 275 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 334
Query: 525 EADSDSD 531
E S+ +
Sbjct: 335 EEVSEEE 341
Score = 29.6 bits (65), Expect = 7.2
Identities = 41/202 (20%), Positives = 78/202 (38%), Gaps = 37/202 (18%)
Query: 269 KKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELET 328
KKR+++QEE+ + I R N + ++ EE R+ + +E
Sbjct: 20 KKRRKEQEEKAE----------IKRLKNSDDRDSKRDSLEEGEL---RD------HCMEI 60
Query: 329 RVRLSKRRAKAGVQSG---TNALLVVKHRDMNEKEL---EAQEARKAQLENH-------- 374
+R S R + ++ ++L + + M+ KE E RK + +H
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGK 120
Query: 375 ----EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASD 430
+ E E + EE++ + E++K +E S E E + +R+
Sbjct: 121 HARVKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMR 180
Query: 431 KSGSGEDESSEDEARAARDKEE 452
+ + E E E RA ++E
Sbjct: 181 EQQKEQREQKERERRAEERRKE 202
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 256 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 305
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 306 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 362
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 363 AEEEVGEGTPQSSALTEG 380
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 241 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 294
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 295 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 342
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 343 NHLLVVPESRFDRDSGES 360
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/279 (19%), Positives = 110/279 (39%), Gaps = 30/279 (10%)
Query: 265 EETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASK-GYEENYFFIFREGDGVYY 323
E +KR R+++++ + ++ARE++ +++ + + RE
Sbjct: 119 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 178
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
+ E R +RR + + +A HR M E + + KA + P E
Sbjct: 179 EQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRPPRER 231
Query: 384 METEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
E + +E+ E E++ D S+SER+ + +S +SGSG +E E+E
Sbjct: 232 FELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 286
Query: 444 ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS------ 497
++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 287 ----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 342
Query: 498 -------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 343 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 381
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 152 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 210
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 211 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 265
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 266 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 325
Query: 525 EADSDSD 531
E S+ +
Sbjct: 326 EEVSEEE 332
Score = 37.4 bits (85), Expect = 0.034
Identities = 42/206 (20%), Positives = 81/206 (39%), Gaps = 31/206 (15%)
Query: 352 KHRDMNEK-------------------ELEAQEARKAQLENHEPEEEEEEEMETE-EKEA 391
KH + EK E E Q+ R+ E+ E + E++E + E+E
Sbjct: 109 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERER 168
Query: 392 GGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD------RDEASDKSGSGEDESSEDEAR 445
++++E+ E+E +E R E R++ SDK + S R
Sbjct: 169 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKA--SHWSRSPPR 226
Query: 446 AARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPS 505
R++ E+ +++ + + Q SD++ + S + S + S S S
Sbjct: 227 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSS---AESSSAESGSGSEEEE 283
Query: 506 GSEHSAQEDGSEAAASDSSEADSDSD 531
E +E+GS + S+ E + + +
Sbjct: 284 EEEEEEEEEGSTSEESEEEEEEEEEE 309
Score = 31.6 bits (70), Expect = 1.9
Identities = 40/193 (20%), Positives = 81/193 (41%), Gaps = 28/193 (14%)
Query: 269 KKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELET 328
KKR+++QEE+ + I R N + ++ EE R+ + +E
Sbjct: 20 KKRRKEQEEKAE----------IKRLKNSDDRDSKRDSLEEGEL---RD------HCMEI 60
Query: 329 RVRLSKRRAKAGVQSG---TNALLVVKHRDMNEKE-LEAQEARKAQLENHEPEEEEEEEM 384
+R S R + ++ ++L + + M+ KE + ++ K + + H +E+E E
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
Query: 385 ETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-----GDRDEASDKSGSGEDES 439
E ++ D+ + + ++ EHS E +R E +R+ + + E
Sbjct: 121 ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ 180
Query: 440 SEDEARAARDKEE 452
E E RA ++E
Sbjct: 181 KERERRAEERRKE 193
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 265 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 314
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 315 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 371
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 372 AEEEVGEGTPQSSALTEG 389
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 250 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 303
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 304 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 351
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 352 NHLLVVPESRFDRDSGES 369
Score = 52.8 bits (125), Expect = 8e-07
Identities = 57/292 (19%), Positives = 111/292 (38%), Gaps = 45/292 (15%)
Query: 265 EETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGV--Y 322
E ++RKR +EE+ K RE+ + + ++ + R DGV +
Sbjct: 117 EREHERRKRHREEQD----------KARREWERQKRREMAREHSRRE----RGNDGVCLF 162
Query: 323 YNELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEE 382
+ LE R +R K Q + R E+ E + R+ + E+ +
Sbjct: 163 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222
Query: 383 EMET------------EEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASD 430
+++ E E G + ++ E++ D S+SER+ + +S
Sbjct: 223 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSA 282
Query: 431 KSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGG 490
+SGSG +E E+E ++EE + +SE++ + ++E+ + S+ S+ +
Sbjct: 283 ESGSGSEEEEEEE----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVS 338
Query: 491 QRSRSHS-------------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
+ S S SG A+E+ E S+ + D
Sbjct: 339 EEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 390
Score = 33.5 bits (75), Expect = 0.50
Identities = 40/215 (18%), Positives = 78/215 (36%), Gaps = 40/215 (18%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETE------------------------ 387
KH + EKE E + ++ + E + E E + E
Sbjct: 109 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQ 168
Query: 388 -----EKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD------RDEASDKSGSGE 436
E+E ++++E+ E+E +E R E R++ SDK +
Sbjct: 169 LERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKA-- 226
Query: 437 DESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSH 496
S R R++ E+ +++ + + Q SD++ + S + S +
Sbjct: 227 SHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSS---AESSSAE 283
Query: 497 SRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S S S E +E+GS + S+ E + + +
Sbjct: 284 SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 318
Score = 29.6 bits (65), Expect = 7.2
Identities = 50/267 (18%), Positives = 100/267 (37%), Gaps = 27/267 (10%)
Query: 269 KKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYYNELET 328
KKR+++QEE+ + I R N + ++ EE R+ + +E
Sbjct: 20 KKRRKEQEEKAE----------IKRLKNSDDRDSKRDSLEEGEL---RD------HCMEI 60
Query: 329 RVRLSKRRAKAGVQSG---TNALLVVKHRDMNEKE-LEAQEARKAQLENHEPEEEEEEEM 384
+R S R + ++ ++L + + M+ KE + ++ K + + H +E+E E
Sbjct: 61 TIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREH 120
Query: 385 ETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEA 444
E ++ EEQ+K + E + S RE G+ + + E +
Sbjct: 121 ERRKRHR----EEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERE 176
Query: 445 RAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFP 504
R R++++ + E A+ ++R + S + + + SH + P P
Sbjct: 177 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
Query: 505 SGSEHSAQEDGSEAAASDSSEADSDSD 531
+ E D SD
Sbjct: 237 PRERFELGDGRKPVKEEKMEERDLLSD 263
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 233 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 282
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 283 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 339
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 340 AEEEVGEGTPQSSALTEG 357
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 218 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 271
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 272 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 319
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 320 NHLLVVPESRFDRDSGES 337
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/279 (19%), Positives = 110/279 (39%), Gaps = 30/279 (10%)
Query: 265 EETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASK-GYEENYFFIFREGDGVYY 323
E +KR R+++++ + ++ARE++ +++ + + RE
Sbjct: 96 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 155
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
+ E R +RR + + +A HR M E + + KA + P E
Sbjct: 156 EQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRPPRER 208
Query: 384 METEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
E + +E+ E E++ D S+SER+ + +S +SGSG +E E+E
Sbjct: 209 FELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 263
Query: 444 ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS------ 497
++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 264 ----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 319
Query: 498 -------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 320 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 358
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 129 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 187
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 188 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 242
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 243 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 302
Query: 525 EADSDSD 531
E S+ +
Sbjct: 303 EEVSEEE 309
Score = 37.7 bits (86), Expect = 0.026
Identities = 47/227 (20%), Positives = 88/227 (38%), Gaps = 37/227 (16%)
Query: 331 RLSKRRAKAGVQSGTNALLVVKHRDMNEK-------------------ELEAQEARKAQL 371
R KRR ++ G KH + EK E E Q+ R+
Sbjct: 71 RKEKRRHRSHSAEGG------KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 124
Query: 372 ENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD------ 424
E+ E + E++E + E+E ++++E+ E+E +E R E
Sbjct: 125 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 184
Query: 425 RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDS 484
R++ SDK + S R R++ E+ +++ + + Q SD++ +
Sbjct: 185 REDYSDKVKA--SHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 242
Query: 485 GSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S + S + S S S E +E+GS + S+ E + + +
Sbjct: 243 SS---AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 286
Score = 33.5 bits (75), Expect = 0.50
Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 6/108 (5%)
Query: 351 VKHR-DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGS 409
V HR D KE + A+ H +E+E E E ++ D+ + + ++
Sbjct: 63 VHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 122
Query: 410 EDEHSGSESEREE-----GDRDEASDKSGSGEDESSEDEARAARDKEE 452
EHS E +R E +R+ + + E E E RA ++E
Sbjct: 123 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 170
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 222 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 271
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 272 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 328
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 329 AEEEVGEGTPQSSALTEG 346
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 207 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 260
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 261 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 308
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 309 NHLLVVPESRFDRDSGES 326
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/279 (19%), Positives = 110/279 (39%), Gaps = 30/279 (10%)
Query: 265 EETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASK-GYEENYFFIFREGDGVYY 323
E +KR R+++++ + ++ARE++ +++ + + RE
Sbjct: 85 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 144
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
+ E R +RR + + +A HR M E + + KA + P E
Sbjct: 145 EQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRPPRER 197
Query: 384 METEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
E + +E+ E E++ D S+SER+ + +S +SGSG +E E+E
Sbjct: 198 FELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 252
Query: 444 ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS------ 497
++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 253 ----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 308
Query: 498 -------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 309 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 347
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 118 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 176
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 177 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 231
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 232 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 291
Query: 525 EADSDSD 531
E S+ +
Sbjct: 292 EEVSEEE 298
Score = 37.4 bits (85), Expect = 0.034
Identities = 42/206 (20%), Positives = 81/206 (39%), Gaps = 31/206 (15%)
Query: 352 KHRDMNEK-------------------ELEAQEARKAQLENHEPEEEEEEEMETE-EKEA 391
KH + EK E E Q+ R+ E+ E + E++E + E+E
Sbjct: 75 KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERER 134
Query: 392 GGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD------RDEASDKSGSGEDESSEDEAR 445
++++E+ E+E +E R E R++ SDK + S R
Sbjct: 135 KMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKA--SHWSRSPPR 192
Query: 446 AARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPS 505
R++ E+ +++ + + Q SD++ + S + S + S S S
Sbjct: 193 PPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSS---AESSSAESGSGSEEEE 249
Query: 506 GSEHSAQEDGSEAAASDSSEADSDSD 531
E +E+GS + S+ E + + +
Sbjct: 250 EEEEEEEEEGSTSEESEEEEEEEEEE 275
Score = 31.6 bits (70), Expect = 1.9
Identities = 28/138 (20%), Positives = 60/138 (43%), Gaps = 9/138 (6%)
Query: 324 NELETRVRLSKRRAKAGVQSG---TNALLVVKHRDMNEKE-LEAQEARKAQLENHEPEEE 379
+ +E +R S R + ++ ++L + + M+ KE + ++ K + + H +E
Sbjct: 22 HRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKE 81
Query: 380 EEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREE-----GDRDEASDKSGS 434
+E E E ++ D+ + + ++ EHS E +R E +R+ +
Sbjct: 82 KEREHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQK 141
Query: 435 GEDESSEDEARAARDKEE 452
+ E E E RA ++E
Sbjct: 142 EQREQKERERRAEERRKE 159
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 11 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 60
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 61 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 117
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 118 AEEEVGEGTPQSSALTEG 135
Score = 55.1 bits (131), Expect = 2e-07
Identities = 37/120 (30%), Positives = 63/120 (52%), Gaps = 13/120 (10%)
Query: 369 AQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDE 427
+ L++ E + E+ E+G GS+EE+E+ E+EGS E ESE EE + +E
Sbjct: 8 SDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSE----ESEEEEEEEEE 63
Query: 428 ASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSN 487
+++GS +E+SE A EE+ S+ + +D + ++E+ S D DSG +
Sbjct: 64 EEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENENHLLVVPESRFDRDSGES 115
Score = 50.1 bits (118), Expect = 5e-06
Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 19/121 (15%)
Query: 333 SKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG 392
S+R+ + S + + + E+E E + + + E E EEEEEEE E G
Sbjct: 16 SERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEE------ETG 69
Query: 393 GSDEEQEKGSS---SEKEGSEDEHSGSES----------EREEGDRDEASDKSGSGEDES 439
+ EE + S+ SE+E SEDE +E+ +R+ G+ +EA ++ G G +S
Sbjct: 70 SNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS 129
Query: 440 S 440
S
Sbjct: 130 S 130
Score = 39.7 bits (91), Expect = 0.007
Identities = 28/134 (20%), Positives = 55/134 (41%), Gaps = 9/134 (6%)
Query: 405 EKEGSEDEHSGSESEREEGDRDEASDKSGSG-----EDESSEDEARAARDKEEIFGSDAD 459
E++ D S+SER+ + +S +SGSG E+E E+E + ++ E + +
Sbjct: 3 ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 62
Query: 460 SEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSH----SRSASPFPSGSEHSAQEDG 515
E++ + + Q + + S + + +H S SG A+E+
Sbjct: 63 EEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEV 122
Query: 516 SEAAASDSSEADSD 529
E S+ + D
Sbjct: 123 GEGTPQSSALTEGD 136
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 59.3 bits (142), Expect = 8e-09
Identities = 41/138 (29%), Positives = 64/138 (46%), Gaps = 15/138 (10%)
Query: 354 RDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEH 413
+D+++ E + A + E+ EEEEEE E EE+E+GS+SE+ E+E
Sbjct: 267 QDISDSERKTSSAESSSAESGSGSEEEEEEEE----------EEEEEGSTSEESEEEEEE 316
Query: 414 SGSESEREEGDRDEASDKSGS--GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDR 471
E E + +EAS++S E+E SEDE R+ E +S D DS + +
Sbjct: 317 EEEEEEETGSNSEEASEQSAEEVSEEEMSEDE---ERENENHLLVVPESRFDRDSGESEE 373
Query: 472 GQAQGGSDNDSDSGSNGG 489
+ + G S G
Sbjct: 374 AEEEVGEGTPQSSALTEG 391
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/138 (30%), Positives = 70/138 (50%), Gaps = 19/138 (13%)
Query: 351 VKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAG-GSDEEQEKGSSSEKEGS 409
VK M E++L + L++ E + E+ E+G GS+EE+E+ E+EGS
Sbjct: 252 VKEEKMEERDL------LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGS 305
Query: 410 EDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E ESE EE + +E +++GS +E+SE A EE+ S+ + +D + ++E
Sbjct: 306 TSE----ESEEEEEEEEEEEEETGSNSEEASEQSA------EEV--SEEEMSEDEERENE 353
Query: 470 DRGQAQGGSDNDSDSGSN 487
+ S D DSG +
Sbjct: 354 NHLLVVPESRFDRDSGES 371
Score = 48.9 bits (115), Expect = 1e-05
Identities = 55/279 (19%), Positives = 110/279 (39%), Gaps = 30/279 (10%)
Query: 265 EETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASK-GYEENYFFIFREGDGVYY 323
E +KR R+++++ + ++ARE++ +++ + + RE
Sbjct: 130 EHERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 189
Query: 324 NELETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEE 383
+ E R +RR + + +A HR M E + + KA + P E
Sbjct: 190 EQKERERRAEERRKEREARREVSA----HHRTMRE---DYSDKVKASHWSRSPPRPPRER 242
Query: 384 METEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
E + +E+ E E++ D S+SER+ + +S +SGSG +E E+E
Sbjct: 243 FELGDGRKPVKEEKME-----ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 297
Query: 444 ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHS------ 497
++EE + +SE++ + ++E+ + S+ S+ + + S
Sbjct: 298 ----EEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENE 353
Query: 498 -------RSASPFPSGSEHSAQEDGSEAAASDSSEADSD 529
S SG A+E+ E S+ + D
Sbjct: 354 NHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGD 392
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/187 (20%), Positives = 70/187 (37%), Gaps = 13/187 (6%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+ RD E +LE + R+ ++ + E+ E++E E +E E + + S+ + ED
Sbjct: 163 RERDRLE-QLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 221
Query: 412 -------EHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDA 464
H R +R E D ++E E+ RD +DSE
Sbjct: 222 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEE-----RDLLSDLQDISDSERKT 276
Query: 465 DSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSS 524
S + ++ GS+ + + + S S E SE A+ S+
Sbjct: 277 SSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSA 336
Query: 525 EADSDSD 531
E S+ +
Sbjct: 337 EEVSEEE 343
Score = 37.7 bits (86), Expect = 0.026
Identities = 47/227 (20%), Positives = 88/227 (38%), Gaps = 37/227 (16%)
Query: 331 RLSKRRAKAGVQSGTNALLVVKHRDMNEK-------------------ELEAQEARKAQL 371
R KRR ++ G KH + EK E E Q+ R+
Sbjct: 105 RKEKRRHRSHSAEGG------KHARVKEKEREHERRKRHREEQDKARREWERQKRREMAR 158
Query: 372 ENHEPEEEEEEEMETE-EKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGD------ 424
E+ E + E++E + E+E ++++E+ E+E +E R E
Sbjct: 159 EHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTM 218
Query: 425 RDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDS 484
R++ SDK + S R R++ E+ +++ + + Q SD++ +
Sbjct: 219 REDYSDKVKA--SHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKT 276
Query: 485 GSNGGGQRSRSHSRSASPFPSGSEHSAQEDGSEAAASDSSEADSDSD 531
S + S + S S S E +E+GS + S+ E + + +
Sbjct: 277 SS---AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEE 320
Score = 33.5 bits (75), Expect = 0.50
Identities = 26/108 (24%), Positives = 44/108 (40%), Gaps = 6/108 (5%)
Query: 351 VKHR-DMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGS 409
V HR D KE + A+ H +E+E E E ++ D+ + + ++
Sbjct: 97 VHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWERQKRREM 156
Query: 410 EDEHSGSESEREE-----GDRDEASDKSGSGEDESSEDEARAARDKEE 452
EHS E +R E +R+ + + E E E RA ++E
Sbjct: 157 AREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKE 204
Score = 30.8 bits (68), Expect = 3.2
Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 11/125 (8%)
Query: 375 EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGS 434
E + +E+E + E K SD+ K S E EG +H E R+ + S
Sbjct: 19 EKKRRKEQEEKAEIKRLKNSDDRDSKRDSLE-EGELRDH-----RMEITIRNSPYRREDS 72
Query: 435 GEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG-GQRS 493
ED ED++ A + +++ + E DE R + + + ++ G + ++
Sbjct: 73 MEDRGEEDDSLAIKPPQQM----SRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKE 128
Query: 494 RSHSR 498
R H R
Sbjct: 129 REHER 133
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 17/125 (13%)
Query: 370 QLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEAS 429
Q +N P+ EEE++ + +E DEE+E+ + EG E+E E E E+ D DE
Sbjct: 150 QEDNEAPDSEEEDDEDGDE-----DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDE-- 202
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489
D++GS E E+ + KEEI D EDD D +E G + + + G G
Sbjct: 203 DEAGSELGEGEEEVGLSYLMKEEI----QDEEDDDDYVEE------GEEEEEEEEGGLRG 252
Query: 490 GQRSR 494
+R R
Sbjct: 253 EKRKR 257
Score = 52.8 bits (125), Expect = 8e-07
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 19/126 (15%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
++++ EA ++ + E+ + ++EEEEE E E G +EE+E+ E E +++ +GS
Sbjct: 149 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEEEDEDEDEDEDEAGS 207
Query: 417 ---ESEREEG----------DRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDD 463
E E E G D ++ D GE+E E+E +K + D+EDD
Sbjct: 208 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK-----RDAEDD 262
Query: 464 ADSDDE 469
+ +D+
Sbjct: 263 GEEEDD 268
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 17/125 (13%)
Query: 370 QLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEAS 429
Q +N P+ EEE++ + +E DEE+E+ + EG E+E E E E+ D DE
Sbjct: 109 QEDNEAPDSEEEDDEDGDE-----DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDE-- 161
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489
D++GS E E+ + KEEI D EDD D +E G + + + G G
Sbjct: 162 DEAGSELGEGEEEVGLSYLMKEEI----QDEEDDDDYVEE------GEEEEEEEEGGLRG 211
Query: 490 GQRSR 494
+R R
Sbjct: 212 EKRKR 216
Score = 52.8 bits (125), Expect = 8e-07
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 19/126 (15%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
++++ EA ++ + E+ + ++EEEEE E E G +EE+E+ E E +++ +GS
Sbjct: 108 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEEEDEDEDEDEDEAGS 166
Query: 417 ---ESEREEG----------DRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDD 463
E E E G D ++ D GE+E E+E +K + D+EDD
Sbjct: 167 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK-----RDAEDD 221
Query: 464 ADSDDE 469
+ +D+
Sbjct: 222 GEEEDD 227
Score = 35.4 bits (80), Expect = 0.13
Identities = 30/106 (28%), Positives = 46/106 (43%), Gaps = 26/106 (24%)
Query: 355 DMNEKELEAQEARKAQ-LENHEPEEEEEEEMETEEKEAGGS------------------- 394
D +++E E EA + E E EEEEE+E E E+++ GS
Sbjct: 126 DEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEI 185
Query: 395 -DEEQEKGSSSE-KEGSEDEHSGSESEREEGDRDEASDKSGSGEDE 438
DEE + E +E E+E G E+ + D ++ G ED+
Sbjct: 186 QDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAED----DGEEEDD 227
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 58.5 bits (140), Expect = 1e-08
Identities = 41/125 (32%), Positives = 61/125 (48%), Gaps = 17/125 (13%)
Query: 370 QLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEAS 429
Q +N P+ EEE++ + +E DEE+E+ + EG E+E E E E+ D DE
Sbjct: 102 QEDNEAPDSEEEDDEDGDE-----DDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDE-- 154
Query: 430 DKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGG 489
D++GS E E+ + KEEI D EDD D +E G + + + G G
Sbjct: 155 DEAGSELGEGEEEVGLSYLMKEEI----QDEEDDDDYVEE------GEEEEEEEEGGLRG 204
Query: 490 GQRSR 494
+R R
Sbjct: 205 EKRKR 209
Score = 52.8 bits (125), Expect = 8e-07
Identities = 35/126 (27%), Positives = 63/126 (50%), Gaps = 19/126 (15%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
++++ EA ++ + E+ + ++EEEEE E E G +EE+E+ E E +++ +GS
Sbjct: 101 DQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPE-GYEEEEEEEEEEDEDEDEDEDEAGS 159
Query: 417 ---ESEREEG----------DRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDD 463
E E E G D ++ D GE+E E+E +K + D+EDD
Sbjct: 160 ELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRK-----RDAEDD 214
Query: 464 ADSDDE 469
+ +D+
Sbjct: 215 GEEEDD 220
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 58.5 bits (140), Expect = 1e-08
Identities = 32/95 (33%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
Query: 357 NEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGS 416
+++E E E K +E E EEEEEE E EE++ +EE+E+G S EG E++ S
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS 570
Query: 417 ESEREEG---DRDEASDKSGSGEDESSEDEARAAR 448
+ E++ G D+ + + S E +S +D + R
Sbjct: 571 D-EKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEER 604
Score = 57.8 bits (138), Expect = 2e-08
Identities = 36/108 (33%), Positives = 52/108 (48%), Gaps = 13/108 (12%)
Query: 375 EPEEEEE-EEMETEEKEAGGSDEEQEK------------GSSSEKEGSEDEHSGSESERE 421
EPEEEE+ E+ ++ EA SDEE EK E+E E+E ESE E
Sbjct: 491 EPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEE 550
Query: 422 EGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDE 469
E + E+ G EDE DE + + ++ + S+ + DSDD+
Sbjct: 551 EEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDD 598
Score = 49.7 bits (117), Expect = 7e-06
Identities = 57/245 (23%), Positives = 100/245 (40%), Gaps = 24/245 (9%)
Query: 264 VEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDGVYY 323
++E +++KR++EE + + K + + + +E + +EG +
Sbjct: 351 LKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTK 410
Query: 324 NELETRVRLS---KRRAKAGVQSGTNALLVVK---HRDMNEKELEAQEARKAQLENHE-- 375
++ E R R K GV+ + L K + D K++ Q K E+ E
Sbjct: 411 SQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELC 470
Query: 376 --PEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSG 433
E E+ E EE EE+E + + E S E+E+ EG++ K
Sbjct: 471 AAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKEN 530
Query: 434 SGEDESSEDEARAARDKE-------EIFGSDADSEDDADSDDEDRGQA-------QGGSD 479
E+E E+E + E E GS+ D ED+ SD++D G+ + SD
Sbjct: 531 PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSD 590
Query: 480 NDSDS 484
++ DS
Sbjct: 591 SEYDS 595
Score = 48.1 bits (113), Expect = 2e-05
Identities = 30/101 (29%), Positives = 51/101 (50%), Gaps = 6/101 (5%)
Query: 353 HRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDE 412
H ++ E E +E + + E+ E EEEEEEE E+E E DEE EK S + G +
Sbjct: 524 HIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSE---GDEEDEKVSDEKDSGKTLD 580
Query: 413 HSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEI 453
S+ + + D D++ ++E + D+A+ +K +
Sbjct: 581 KKPSKEMSSDSEYDSDDDRT---KEERAYDKAKRRIEKRRL 618
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/163 (23%), Positives = 75/163 (46%), Gaps = 13/163 (7%)
Query: 354 RDMNEKELEAQEARKAQLENH--EPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSED 411
+++ E LEAQ KA E +P E EEE +++K+ G +++ ++ E ED
Sbjct: 60 KELEELSLEAQGI-KADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELED 118
Query: 412 EHSGSESEREEGDRDEASDKSGSGEDES-----SEDEARAARDKEEIFGSDADSEDDADS 466
+ S S+ + + SGS +D+ + + +A + ++ GS+ D ++
Sbjct: 119 KDSKSKKTA----KPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKI 174
Query: 467 DDEDRGQAQGGSDNDSDSG-SNGGGQRSRSHSRSASPFPSGSE 508
+ R + G S ++SD + GQ+ ++ SG+E
Sbjct: 175 KERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNE 217
Score = 43.1 bits (100), Expect = 6e-04
Identities = 34/162 (20%), Positives = 72/162 (44%), Gaps = 17/162 (10%)
Query: 359 KELEAQEARKAQLENHEPEEEEEE----EMETEEKEAGGSDEEQEKGSSSEKEGSEDEHS 414
KE E Q+++ + + + ++ +E+ E+E EA G ++E + E +E+E +
Sbjct: 33 KEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFT 92
Query: 415 GSESER--EEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDDEDRG 472
+ ++ ++G + D ++ + A+ K E++ D +D + +G
Sbjct: 93 SKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG 152
Query: 473 QAQ------GGSDNDSDSGSNGGGQRSRSHSRSASPFPSGSE 508
+AQ GS+ D D+ ++ + SR S SG E
Sbjct: 153 KAQKSNKKWDGSEEDEDN-----SKKIKERSRINSSGESGDE 189
Score = 41.2 bits (95), Expect = 0.002
Identities = 28/91 (30%), Positives = 46/91 (50%), Gaps = 3/91 (3%)
Query: 344 GTNALLVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSS 403
G + VK E+E E +E + E E EE E E E +E++ SD E++ G +
Sbjct: 520 GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSD-EKDSGKT 578
Query: 404 SEKEGSEDEHSGSE--SEREEGDRDEASDKS 432
+K+ S++ S SE S+ + + A DK+
Sbjct: 579 LDKKPSKEMSSDSEYDSDDDRTKEERAYDKA 609
Score = 39.3 bits (90), Expect = 0.009
Identities = 27/143 (18%), Positives = 65/143 (45%), Gaps = 4/143 (2%)
Query: 349 LVVKHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEG 408
+ VK + NE+E +++ +K + + ++ + E E+K++ ++ K G
Sbjct: 79 VAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDS--KSKKTAKPKVEMYSG 136
Query: 409 SEDEHSGSESEREEGDRDEASDKSGSGEDESSEDEARAARDKEEIFGSDADSEDDADSDD 468
S+D+ ++ ++ + + S+K G +E ED ++ +++ I S +S D++D
Sbjct: 137 SDDDDDFNKLPKKAKGKAQKSNKKWDGSEE-DEDNSKKIKERSRI-NSSGESGDESDEFL 194
Query: 469 EDRGQAQGGSDNDSDSGSNGGGQ 491
+ R + N G +
Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNE 217
Score = 38.5 bits (88), Expect = 0.015
Identities = 47/238 (19%), Positives = 92/238 (38%), Gaps = 42/238 (17%)
Query: 261 FLPVEETLKKRKRDQEEEMDYAPDDVYDYKIAREYNWNVKNKASKGYEENYFFIFREGDG 320
F + + K + + ++ D + +D + K +E + + + G E + F R+G
Sbjct: 143 FNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERS-RINSSGESGDESDEFLQSRKG-- 199
Query: 321 VYYNELETRVRLSKRRAKAGVQSGTN--------ALLVVKHRDMNEKELEAQEARKAQLE 372
+ + K + ++SG + K + E+E + ++ KA+L
Sbjct: 200 --------QKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLR 251
Query: 373 NHEPEEEEEEEMETEEKEAGGSDEEQEKGSSSEKEGSEDEHSG----SESERE------- 421
+ +E+EE+ET +K+ E Q K + +G SE + E
Sbjct: 252 ----KLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAED 307
Query: 422 --EGDRDEASDKSGSGEDESSEDEARAARDK------EEIFGSDADSEDDADSDDEDR 471
EGD+ + K GE E E E + K +E + E+ ++E+R
Sbjct: 308 DNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEER 365
Score = 32.3 bits (72), Expect = 1.1
Identities = 42/200 (21%), Positives = 74/200 (37%), Gaps = 9/200 (4%)
Query: 327 ETRVRLSKRRAKAGVQSGTNALLVVKHRDMNEKELEAQEARKAQLENHE-PEEEEEEEME 385
E + +L K + K +++G K ++ K E K ++ P EE+ E
Sbjct: 245 EEKAKLRKLKEKEELETGKKDQS--KQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP 302
Query: 386 T--EEKEAGGSDEEQEKGSSSEKEGSEDEHSGSESEREEGDRDEASDKSGSGEDESSEDE 443
T E+ G ++ +K EKE E E S+ EA K E+ +E
Sbjct: 303 TAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE 362
Query: 444 ARAARDKEEIFGSDADSEDDADSDDEDRGQAQGGSDNDSDSGSNGGGQRSRSHSRSASPF 503
+ EE+ +A +++ + E R + + + G ++S R A
Sbjct: 363 EERIKRLEEL---EAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKS-QREARAR 418
Query: 504 PSGSEHSAQEDGSEAAASDS 523
+ Q G E + DS
Sbjct: 419 AEATLKLLQAQGVEVPSKDS 438
Score = 32.0 bits (71), Expect = 1.4
Identities = 20/76 (26%), Positives = 43/76 (56%), Gaps = 4/76 (5%)
Query: 352 KHRDMNEKELEAQEARKAQLENHEPEEEEEEEMETEEKEAGGS-DEEQEKGSSSEKE-GS 409
+ + ++E E +E + + E E +EE+E+ ++EK++G + D++ K SS+ E S
Sbjct: 538 EEEEEEDEESEEEEEEEGESEGSEGDEEDEK--VSDEKDSGKTLDKKPSKEMSSDSEYDS 595
Query: 410 EDEHSGSESEREEGDR 425
+D+ + E ++ R
Sbjct: 596 DDDRTKEERAYDKAKR 611
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,756,237
Number of Sequences: 37866
Number of extensions: 1154883
Number of successful extensions: 39204
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 873
Number of HSP's successfully gapped in prelim test: 917
Number of HSP's that attempted gapping in prelim test: 8731
Number of HSP's gapped (non-prelim): 12309
length of query: 531
length of database: 18,247,518
effective HSP length: 107
effective length of query: 424
effective length of database: 14,195,856
effective search space: 6019042944
effective search space used: 6019042944
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.