Guide to the Human Genome
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Search of human proteins with 42476118

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo
sapiens]
         (829 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo sa...  1702   0.0  
gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo sa...  1588   0.0  
gi|166706917 hypothetical protein LOC199920 [Homo sapiens]            142   1e-33
gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]       94   7e-19
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     77   9e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   2e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    72   3e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    70   6e-12
gi|210032580 SET domain containing 1B [Homo sapiens]                   69   1e-11
gi|55750053 atrophin-1 [Homo sapiens]                                  68   3e-11
gi|55750041 atrophin-1 [Homo sapiens]                                  68   3e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    68   4e-11
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    67   7e-11
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    67   7e-11
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       64   4e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    62   2e-09
gi|150170670 piccolo isoform 2 [Homo sapiens]                          62   2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens]                          62   2e-09
gi|153792074 proline rich 12 [Homo sapiens]                            60   6e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    60   8e-09
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              60   1e-08
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ...    60   1e-08
gi|148727255 microtubule associated serine/threonine kinase fami...    60   1e-08
gi|41281612 zinc finger protein 828 [Homo sapiens]                     59   1e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          58   4e-08
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          58   4e-08
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          58   4e-08
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         57   5e-08
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa...    57   7e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         57   7e-08

>gi|42476118 FYN binding protein (FYB-120/130) isoform 1 [Homo
           sapiens]
          Length = 829

 Score = 1702 bits (4407), Expect = 0.0
 Identities = 829/829 (100%), Positives = 829/829 (100%)

Query: 1   MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP 60
           MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP
Sbjct: 1   MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP 60

Query: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL 120
           KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL
Sbjct: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL 120

Query: 121 PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF 180
           PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF
Sbjct: 121 PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF 180

Query: 181 MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240
           MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP
Sbjct: 181 MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240

Query: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300
           AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN
Sbjct: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300

Query: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP 360
           QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP
Sbjct: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP 360

Query: 361 NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
           NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP
Sbjct: 361 NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420

Query: 421 PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK 480
           PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK
Sbjct: 421 PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK 480

Query: 481 KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII 540
           KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII
Sbjct: 481 KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII 540

Query: 541 RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600
           RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE
Sbjct: 541 RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600

Query: 601 QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKD 660
           QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKD
Sbjct: 601 QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKD 660

Query: 661 DRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK 720
           DRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK
Sbjct: 661 DRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK 720

Query: 721 AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES 780
           AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES
Sbjct: 721 AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES 780

Query: 781 LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND 829
           LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND
Sbjct: 781 LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND 829


>gi|40788007 FYN binding protein (FYB-120/130) isoform 2 [Homo
           sapiens]
          Length = 783

 Score = 1588 bits (4111), Expect = 0.0
 Identities = 783/829 (94%), Positives = 783/829 (94%), Gaps = 46/829 (5%)

Query: 1   MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP 60
           MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP
Sbjct: 1   MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSP 60

Query: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL 120
           KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL
Sbjct: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL 120

Query: 121 PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF 180
           PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF
Sbjct: 121 PKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKF 180

Query: 181 MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240
           MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP
Sbjct: 181 MSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240

Query: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300
           AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN
Sbjct: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300

Query: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP 360
           QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP
Sbjct: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP 360

Query: 361 NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
           NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP
Sbjct: 361 NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420

Query: 421 PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK 480
           PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK
Sbjct: 421 PRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEK 480

Query: 481 KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII 540
           KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII
Sbjct: 481 KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEII 540

Query: 541 RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600
           RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE
Sbjct: 541 RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600

Query: 601 QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKD 660
           QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDG                        
Sbjct: 601 QDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDADDG------------------------ 636

Query: 661 DRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK 720
                                 FPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK
Sbjct: 637 ----------------------FPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGK 674

Query: 721 AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES 780
           AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES
Sbjct: 675 AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES 734

Query: 781 LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND 829
           LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND
Sbjct: 735 LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND 783


>gi|166706917 hypothetical protein LOC199920 [Homo sapiens]
          Length = 728

 Score =  142 bits (359), Expect = 1e-33
 Identities = 146/517 (28%), Positives = 228/517 (44%), Gaps = 82/517 (15%)

Query: 328 QSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSY 387
           Q+ EK+   ++   PK KPLP + +LGPPPPKP+RPP V+L  F +  +    ++G+ + 
Sbjct: 250 QAPEKQPDVRHHHLPKTKPLPSIDSLGPPPPKPSRPPIVNLQAFQRQPAAVPKTQGEVTV 309

Query: 388 STTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----NIKPPFDLKSPVNEDNQDGVT 443
              SL P    +   + P    H  +  +  L       N+    ++  P  E    G+ 
Sbjct: 310 EEGSLSPERLFNAEFEEP----HNYEATISYLRHSGNSINLCTAKEIADPTYE---VGI- 361

Query: 444 HSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKK 503
                    EE    G+ +   E S + E K+ K EK+  EL K +  EKE     + K 
Sbjct: 362 ---------EELQKPGKNFPYPEPSAKHEDKKMK-EKQPCEL-KPKNTEKEPYSNHVFKV 410

Query: 504 FKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIK 563
               G  + I +        G +N L+ KQ   I+II+    PEG  L R ++G  G+++
Sbjct: 411 DACEGTPEKIQMTNV---HTGRRNMLAGKQEAMIDIIQTNPCPEGPKLARHSQGHCGHLE 467

Query: 564 TTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDV----AEQDDISSHSQSGSGGIFPPP 619
                 +   L + K S           +E+YDDV     E   ++  S   S       
Sbjct: 468 VLESTKETPDLGVSKTS--------SISEEIYDDVEYSRKEVPKLNYSSSLASSSEENRE 519

Query: 620 PDDDIY---DGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKDDRKKSIREKPKVSDSD 676
             +D+Y   +   + D D    L+           + +  K + DR K  + K K    +
Sbjct: 520 LYEDVYKTKNNYPKIDLDGKEALK----------RLQQFFKKEKDRFKIKKTKSK----E 565

Query: 677 NNEGSSFPAPPKQLDMGDE-VYDDVDTSD----------------------FPVSSAEMS 713
           N    S   P  +L   +  +YDDVD S+                         + AE S
Sbjct: 566 NLSAFSILLPDLELKSQEVIIYDDVDLSEKESKDEDKLKMWKPKFLTPKEKKEKNGAEES 625

Query: 714 QGTNVGK-AKTEEKDLKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRD 772
           +  +     KT++++L+K  + ++EEK FR++FKYD EI ++ +T V  S  S+  G  D
Sbjct: 626 ESFSPRNFFKTKKQNLEK-NRMKREEKLFRERFKYDKEI-IVINTAVACSNNSRN-GIFD 682

Query: 773 LQVKPGESLEVIQTTDDTKVLCRNEEGKYGYVLRSYL 809
           L + PGE LEVI TT+   V+CRN +GKYGYVL  +L
Sbjct: 683 LPISPGEELEVIDTTEQNLVICRNSKGKYGYVLIEHL 719



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)

Query: 469 KEREKKREKEEK-----------KRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAK 517
           KE+++K   EE            K+  LEK   K +EK  +E   +FK    I VI+ A 
Sbjct: 614 KEKKEKNGAEESESFSPRNFFKTKKQNLEKNRMKREEKLFRE---RFKYDKEIIVINTAV 670

Query: 518 ACC-DVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDS 573
           AC  + + G  +L    GE++E+I  T+  +   + R ++G YGY+    ++  + S
Sbjct: 671 ACSNNSRNGIFDLPISPGEELEVIDTTE--QNLVICRNSKGKYGYVLIEHLDFKHQS 725


>gi|40807475 PML-RARA regulated adaptor molecule 1 [Homo sapiens]
          Length = 669

 Score = 93.6 bits (231), Expect = 7e-19
 Identities = 159/617 (25%), Positives = 222/617 (35%), Gaps = 123/617 (19%)

Query: 47  PPAGPSNVPKFGSPKPPVAV----KPSSEEKPDKEPKPPFLKPTGAGQRFGTP----ASL 98
           PP   +++PK   P PP       KPS  E  D   K P L  T   ++   P    A L
Sbjct: 96  PPPEVTDLPK--KPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPL 153

Query: 99  TTRDPEAKVGFLKPVGPK----PINLPKEDSKPTFP---WPP--------GNKPSLHSVN 143
               PE      KP+ P     P   P E     FP   W P          +P L +  
Sbjct: 154 KASLPEPGAPARKPLQPDELSHPARPPSEPKSGAFPRKLWQPEAGEATPRSPQPELSTFP 213

Query: 144 QDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQ-------DLEPK---PLF 193
           +    KP  P+    P      Q    PK +  + +F  A+Q         EPK     F
Sbjct: 214 K----KPAQPEFNVYPKKPPQPQVGGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAF 269

Query: 194 PKPA-------FGQKPPLST--ENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPARED 244
           PK A       F +KPP     + +     P  +V   +  PA     SK  P +P    
Sbjct: 270 PKKASQPPLSDFPKKPPQPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPP-QPELGG 328

Query: 245 SENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEEL 304
                   E +SLP    +L+P   R GP    +  E     K       F     +  L
Sbjct: 329 LPRTSSEPEFNSLPRK--LLQP--ERRGPPRKFSQPEPSAVLKRHPQPEFFGDLPRKPPL 384

Query: 305 ASGTPPA-----------RFPKAPSKLTVGGP-WGQ-----SQEKEKGDKNSATPKQKPL 347
            S    +           R P +P     G P W       S     G + S  P+++PL
Sbjct: 385 PSSASESSLPAAVAGFSSRHPLSPGFGAAGTPRWRSGGLVHSGGARPGLRPSHPPRRRPL 444

Query: 348 PPLFTLGPPPPKPNRPPN-VDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPL 406
           PP  +LG PP KP  PP  VD+  F + S+ +   +   S              A+    
Sbjct: 445 PPASSLGHPPAKPPLPPGPVDMQSFRRPSAASIDLRRTRS--------------AAGLHF 490

Query: 407 PASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIE 466
               P   PVP          ++L   V E   D      G       Q +     +D  
Sbjct: 491 QDRQPEDIPVPD-------EIYELYDDV-EPRDDSSPSPKGRDEAPSVQQAARRPPQDPA 542

Query: 467 ASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDV---- 522
             KE++ + ++      +L  K+ ++ EK E+E +KKFK  G I V+H  K   D     
Sbjct: 543 LRKEKDPQPQQLPPMDPKL-LKQLRKAEKAEREFRKKFKFEGEI-VVH-TKMMIDPNAKT 599

Query: 523 -KGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSL 581
            +GG   L  ++GE +E+I  T N E   L R  +G YGY+  TA+              
Sbjct: 600 RRGGGKHLGIRRGEILEVIEFTSNEE--MLCRDPKGKYGYVPRTAL-------------- 643

Query: 582 GAPSRPIEDDQEVYDDV 598
                P+E   EVYDDV
Sbjct: 644 ----LPLE--TEVYDDV 654



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 56/160 (35%), Positives = 87/160 (54%), Gaps = 26/160 (16%)

Query: 687 PKQLDMGDEVY---DDV----DTSDFPVSSAEMSQGTNVGK------AKTEEKD------ 727
           P+ + + DE+Y   DDV    D+S  P    E        +      A  +EKD      
Sbjct: 495 PEDIPVPDEIYELYDDVEPRDDSSPSPKGRDEAPSVQQAARRPPQDPALRKEKDPQPQQL 554

Query: 728 -------LKKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGES 780
                  LK+L+K EK E++FRKKFK++GEI V     +  +  +++ G + L ++ GE 
Sbjct: 555 PPMDPKLLKQLRKAEKAEREFRKKFKFEGEIVVHTKMMIDPNAKTRRGGGKHLGIRRGEI 614

Query: 781 LEVIQTTDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDI 820
           LEVI+ T + ++LCR+ +GKYGYV R+ L   + E+YDD+
Sbjct: 615 LEVIEFTSNEEMLCRDPKGKYGYVPRTALLPLETEVYDDV 654



 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 96/374 (25%), Positives = 130/374 (34%), Gaps = 42/374 (11%)

Query: 65  AVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKED 124
           A +P   + P K PKP F K     Q   +        PE     LKP  P+  +LPK+ 
Sbjct: 24  ASQPEPSDLPKKPPKPEFGKLKKFSQPELSEHPKKAPLPEFGAVSLKPPPPEVTDLPKKP 83

Query: 125 SKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSAS 184
             P     P  KP    V    DL    PK  P P  ++  +K +  +L+ +  KF    
Sbjct: 84  PPPEVTDLP-KKPPPPEVT---DL----PKKPPPPEVTDLPKKPSKLELSDLSKKFPQLG 135

Query: 185 QDLEP-KPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPA--PLGVRSKSGPLKPA 241
               P KPL P+                 E+P+K      G+PA  PL     S    PA
Sbjct: 136 ATPFPRKPLQPEVG---------------EAPLKASLPEPGAPARKPLQPDELS---HPA 177

Query: 242 REDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQ 301
           R  SE K  A       FP  + +P A    P   +        +      N +  K  Q
Sbjct: 178 RPPSEPKSGA-------FPRKLWQPEAGEATPRSPQPELSTFPKKPAQPEFNVYPKKPPQ 230

Query: 302 EELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPN 361
            ++  G P    P+         P  + Q  E    +SA PK+   PPL      P KP 
Sbjct: 231 PQV-GGLPKKSVPQPEFSEAAQTPLWKPQSSEPKRDSSAFPKKASQPPLSDF---PKKPP 286

Query: 362 RPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPS--L 419
           +P   DLT+       +   K        +L   PP       P  +S P    +P   L
Sbjct: 287 QPELGDLTRTSSEPEVSVLPKRPRPAEFKALSKKPPQPELGGLPRTSSEPEFNSLPRKLL 346

Query: 420 PPRNIKPPFDLKSP 433
            P    PP     P
Sbjct: 347 QPERRGPPRKFSQP 360



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 39/151 (25%), Positives = 52/151 (34%), Gaps = 23/151 (15%)

Query: 298 KINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLG--P 355
           K +Q EL+     A  P+          +G    K    + +  PK+ P P +  L   P
Sbjct: 46  KFSQPELSEHPKKAPLPE----------FGAVSLKPPPPEVTDLPKKPPPPEVTDLPKKP 95

Query: 356 PPP-------KPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPA 408
           PPP       KP  P   DL K       +  SK       T  P  P      + PL A
Sbjct: 96  PPPEVTDLPKKPPPPEVTDLPKKPSKLELSDLSKKFPQLGATPFPRKPLQPEVGEAPLKA 155

Query: 409 SHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQ 439
           S P     P  P R    P +L  P    ++
Sbjct: 156 SLPE----PGAPARKPLQPDELSHPARPPSE 182


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 76.6 bits (187), Expect = 9e-14
 Identities = 109/435 (25%), Positives = 142/435 (32%), Gaps = 53/435 (12%)

Query: 9   NPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKP------ 62
           N  EDVS    P  + G    +  Q        QG  SPP  P   P  G  +P      
Sbjct: 18  NLNEDVSQEESPSLIAGNPQGAPPQGGNK---PQGPPSPPGKPQGPPPQGGNQPQGPPPP 74

Query: 63  ---PVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPIN 119
              P    P    KP   P P   KP G       P    +R P +  G  KP GP P  
Sbjct: 75  PGKPQGPPPQGGNKPQGPPPPG--KPQGP-----PPQGDKSRSPRSPPG--KPQGPPP-- 123

Query: 120 LPKEDSKPTFPWPPGNKPS---LHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV 176
             +  ++P  P PP  KP        N+     P G   GP PP  +N+ + +       
Sbjct: 124 --QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-PPQGDNKSRSSRSPPGKP 180

Query: 177 KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSG 236
           +G         +  P  P P   Q PP    N  +   P       +G P     +S+S 
Sbjct: 181 QGPPPQGGNQPQGPP--PPPGKPQGPPPQGGNKPQGPPPP---GKPQGPPPQGDNKSQSA 235

Query: 237 PLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQ 296
              P +          +    P P     P   +G P     G  K +            
Sbjct: 236 RSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPP---PQGGNKPQGPPPPGKPQGPP 287

Query: 297 SKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPP 356
            +   +  +S +PP + P+ P     GG   Q      G      P+    P     GPP
Sbjct: 288 PQGGSKSRSSRSPPGK-PQGPPPQ--GGNQPQGPPPPPGKPQGPPPQGGNKPQ----GPP 340

Query: 357 PP-KPNRPPNVDLTKFHKTSS--GNSTSKGQTSYSTTSLPPPPPSHPASQPPL-PASHPS 412
           PP KP  PP    +K     S  G      Q   +    PPPP      QP   PA  P 
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ 400

Query: 413 QPPVPSLPPRNIKPP 427
            PP P    R  +PP
Sbjct: 401 GPPRPPQGGRPSRPP 415



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 59/229 (25%), Positives = 77/229 (33%), Gaps = 20/229 (8%)

Query: 207 ENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKP 266
           E+  ++ESP     + +G+P P G     GP  P  +        G     P P     P
Sbjct: 21  EDVSQEESPSLIAGNPQGAP-PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPP----PP 75

Query: 267 AASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPW 326
              +G P    N    K        K         +  +  +PP + P+ P     GG  
Sbjct: 76  GKPQGPPPQGGN----KPQGPPPPGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQ--GGNQ 128

Query: 327 GQSQEKEKGDKNSATPKQKPLPPLFTLGPPPP-KPNRPPNVDLTKFHKTSSGNSTSKGQT 385
            Q      G      P+    P     GPPPP KP  PP     K   + S     +G  
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQ----GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPP 184

Query: 386 SYSTTSL--PPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKS 432
                    PPPPP  P   PP   + P  PP P   P+   P  D KS
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGDNKS 232



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 43/161 (26%), Positives = 63/161 (39%), Gaps = 19/161 (11%)

Query: 288 IDAAKNTFQSKINQEE---LASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQ 344
           + +A+N     ++QEE   L +G P    P+  +K   G P    + +    +    P+ 
Sbjct: 13  LSSAQN-LNEDVSQEESPSLIAGNPQGAPPQGGNK-PQGPPSPPGKPQGPPPQGGNQPQG 70

Query: 345 KPLPPLFTLGPPP---------PKPNRP----PNVDLTKFHKTSSGNSTSKGQTSYSTTS 391
            P PP    GPPP         P P +P    P  D ++  ++  G          +   
Sbjct: 71  PPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 130

Query: 392 LPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKS 432
            PPPPP  P   PP   + P  PP P   P+   P  D KS
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPG-KPQGPPPQGDNKS 170


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 108/419 (25%), Positives = 141/419 (33%), Gaps = 51/419 (12%)

Query: 46   SPPAGPSNVPKFGSPKPPVAVKPS-----SEEKPDKEPKPPFLKPTGAGQRFGTPASLTT 100
            SP  GP+      +P PP A  PS     +   P   P PP   P        TP+    
Sbjct: 949  SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008

Query: 101  RDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPP 160
              P A         P     PK  S P    PP  K S  +        PL PK  PT P
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT-------PL-PKGAPTTP 1060

Query: 161  TSENEQKQAFPKLTGVKG-KFMSASQDLEPK--PLFPKPAFGQKPPLSTENSHED---ES 214
             +     +  P    +KG     A+    PK  P  P P     PP +T  S +      
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120

Query: 215  PMKNVSSSKGS--PAPLGVRS----KSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAA 268
            P K   ++  +  P+P G  +    K  P  PA      K   G +++ P  G    PAA
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK---GGLATPPPKGAPTTPAA 1177

Query: 269  SRGGP--GLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAP-SKLTVGGP 325
            +   P  GL+    +           +            + T PA  P +P   L    P
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237

Query: 326  WG------QSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPN--RPPNVDLTKFHKTSSG 377
             G       +    KG   +  PK  P PP  T  PP  K     PP       HK +  
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT--PPSLKGGLATPP-------HKGAPN 1288

Query: 378  NS--TSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP-PRNIKPPFDLKSP 433
             +  T         TS P   P+ PA+ PP P   P  PP    P P  + PP    +P
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTP 1347



 Score = 73.2 bits (178), Expect = 9e-13
 Identities = 106/405 (26%), Positives = 136/405 (33%), Gaps = 58/405 (14%)

Query: 48   PAGPSNVPKFGSPK---PPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPE 104
            P    N P   SP+    P+A    + E P   P P  L P G      TP      D  
Sbjct: 702  PTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS-LPPAG------TPPGTKKVDGI 754

Query: 105  AKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPT---PPT 161
            +    L PV   P   P EDS  +      +K +L  +       PLG    P    PPT
Sbjct: 755  SHTSALAPVASSPKECPTEDSGASAT--ASSKGTLTYLADSPS--PLGVSVSPQTKRPPT 810

Query: 162  SENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSS 221
             +       P      G   S    +E   L       Q    S   +H    P     S
Sbjct: 811  KKGSAGPDTPI-----GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPP-----S 860

Query: 222  SKGSPAPLGVR--SKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNG 279
             KG+P P  V   S  G   P +E          + +LPFP       A +  P LS   
Sbjct: 861  PKGAPTPSAVTPLSPKGVTLPPKETP-----TPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 280  EEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQE-------- 331
               K+ R   A K    S   +    + TPPA  P +P     GGP   S +        
Sbjct: 916  SSPKKARATPAPKGIPASPSPK---GAPTPPAATPPSPK----GGPATPSPKWAPTPPAA 968

Query: 332  ---KEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYS 388
                 KG   + +PK  P PP  T    PP P   P     K   T    +    + S +
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAAT----PPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 389  TTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSP 433
             T  P    + PA+ PP P   P+  P+P   P    P   L SP
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT--PAATLPSP 1067



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 104/393 (26%), Positives = 137/393 (34%), Gaps = 61/393 (15%)

Query: 46   SPPAGPSNVPKFGSPKPPVAVKPSSEEKPDK-----EPKPPFLKPTGAGQRFGTPASLTT 100
            SP  GP+  P  G+P PP A  PS +  P        P PP + P       GTP +L  
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK---GTP-TLPA 1351

Query: 101  RDPEAKVGFLKP---VGP-KPINLPKEDSKPTF-PWPPGNKPSLHSVNQDHD---LKPLG 152
              P +K G   P    GP  P   P     P   P  P   P++ S   D     + PL 
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411

Query: 153  PKSGP-TPPTSENEQKQAF-----PKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLST 206
            PK  P TP T E     +      P +T V  K   A+   +  P  P        P  T
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471

Query: 207  ENSHEDESPMKNVSSSK------GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFP 260
              S ++    K V++S        +PAP+G      P  PA   S  K+     SS   P
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMG-----APTLPAVIPSSPKEVPATPSSRRDP 1526

Query: 261  GVVLKPAASRGGPG-LSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSK 319
                    S+  P  L+           + + K T    I   + A  TP ++   +P  
Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT--PAIPTPKEAPATPSSKEASSPPA 1584

Query: 320  LTVGGPWGQSQEKE---KGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSS 376
            +T     G    KE        S +PK+ P PP  T    PP P + P     K      
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT----PPSPEKGPATPAPK------ 1634

Query: 377  GNSTSKGQTSYSTTSLPPPPPSHPASQPPLPAS 409
                        T + PP  PS     P  PAS
Sbjct: 1635 -----------GTPTSPPVTPSSLKDSPTSPAS 1656



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 106/437 (24%), Positives = 137/437 (31%), Gaps = 52/437 (11%)

Query: 46   SPPAGPSNVPKFGSPKPPVAVKPSSE-----EKPDKEPKPPFLKPTGA-GQRFGTPASLT 99
            SP  GP+     G+P PP A  PS +       P   P PP + P    G    TP    
Sbjct: 972  SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031

Query: 100  TRDPEAKVGFLKPVGPKPINLPK---EDSKPTFPWPPGNK--PSLHSVNQDHDLKPLGPK 154
               P A         P    LPK        T P P G    PSL          P  PK
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091

Query: 155  SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPK-----PLFPKPAFGQKPPLS--TE 207
             GP  P+ +             KG   +      P      P  PK      PP    T 
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 208  NSHEDESPMKNVSSS--KGSP--------APLGVRS----KSGPLKPAREDSENKDHAGE 253
             +    SP   +++   KG+P        +P G  +    K  P  PA      K   G 
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK---GG 1208

Query: 254  ISSLPFPGVVLKPAASRGGP--GLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPA 311
            +++    G    PAA+   P  GL+    +           +            + TPPA
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268

Query: 312  RFPKA-------PSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL-------GPPP 357
              P +       P       P   +    KG   ++ PK  P PP  T        G PP
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328

Query: 358  PK-PNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPV 416
            PK    PP V       T +  +T+       TT      P+ PA+ P         PP 
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS 1388

Query: 417  PSLPPRNIKPPFDLKSP 433
            P   P    P  D  SP
Sbjct: 1389 PKRGPAIPSPKGDPTSP 1405



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 123/484 (25%), Positives = 171/484 (35%), Gaps = 57/484 (11%)

Query: 44   NASPPAGPSNVPKFGSPKPPVAVKPSSEEKP-DKEPKPPFLKPTGAGQRFGTPASLTTRD 102
            ++SP   P+     G+P  P  +  S +E P     +   + PT       TPA+L  ++
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546

Query: 103  ----PEAKVGFLK--PVGPKPINLPKEDSKPTFPWPPGNKPSLH--SVNQDHDLKP---- 150
                P   V   K  P  P P   P   S      PP   PS +  + +    L P    
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606

Query: 151  -LGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENS 209
               PK  PTPP       +  P     KG     S  + P  L   P      P S    
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKG--TPTSPPVTPSSLKDSPT----SPASVTCK 1660

Query: 210  HEDESPMKNVSSSKGSPAPLGVRS-KSGPLKPAREDS------ENKDHAGEISSLPFPGV 262
                 P     +SKG PA  G  + K   + PA E +        K    + SS   P +
Sbjct: 1661 MGATVP----QASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716

Query: 263  VLKPAASRGGPG-LSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
               P+A  G  G LS          + D++K       +        PP    KA + LT
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE--SKASTPLT 1774

Query: 322  VGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSG---N 378
                   + EK      SA+    P PP+     P P P  PP     +F  +S G    
Sbjct: 1775 AA-----AFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPK---QQFLPSSPGLVLE 1826

Query: 379  STSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP-PRNIKPPF---DLKSPV 434
            S SK         L P  P  P S        P Q  + ++P P++   P      K PV
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPIS-----GGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881

Query: 435  NEDNQDGVTHSDGAGNLD--EEQDSEGETYEDIEASKEREKKREKEEK-KRLELEKKEQK 491
             ++N+   T SD   ++   EEQDS   T +  + +   E   E   K K+   EKK +K
Sbjct: 1882 TKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARK 1941

Query: 492  EKEK 495
               K
Sbjct: 1942 AMSK 1945



 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 96/412 (23%), Positives = 133/412 (32%), Gaps = 42/412 (10%)

Query: 45   ASPPAGPSNVPKFGSPKPPVAVKPSSEEKP-------DKEPK--PPFLKPTGAGQRFGTP 95
            ++P  GP+     G P  P    PS +E P          PK  P    P GA       
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVI 1509

Query: 96   ASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKS 155
             S     P        P+ P    L K+      P      P++   +         PK 
Sbjct: 1510 PSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 156  GPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESP 215
             P  P+S+          +  KG        + P    P P     PP  T  S E    
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE---- 1625

Query: 216  MKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGL 275
                     +PAP G      P  P    S  KD     +S+        P AS+G P  
Sbjct: 1626 -----KGPATPAPKGT-----PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA- 1674

Query: 276  SKNGEEKKEDRKIDAAKNTF-----QSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQ 330
             K     KE     A ++T        K  Q + +S T P   P   +K    GP     
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA 1734

Query: 331  EK-----EKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQT 385
                   +K    +A  K     P   L PP  K + P  +    F K      ++    
Sbjct: 1735 PAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTP--LTAAAFEKVLPKPESA---- 1788

Query: 386  SYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNED 437
              S ++ P PP S P +  P+P   P Q  +PS P   ++ P    +P +ED
Sbjct: 1789 --SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADED 1838



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 103/420 (24%), Positives = 129/420 (30%), Gaps = 104/420 (24%)

Query: 7    GGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAV 66
            GG  T  +     P   T P+   G        + +G   PPA     PK G   PP   
Sbjct: 1069 GGPATPSLKGAPTPPAATPPSPKGGPATP----SPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 67   KPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSK 126
             P++       PK     P       G P +     P  K G   P  PK          
Sbjct: 1125 APTTPAATPPSPKGGLATPPPK----GAPTTPAATPPSPKGGLATP-PPK--------GA 1171

Query: 127  PTFP--WPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSAS 184
            PT P   PP  K  L + +         PK  PT P +     +        KG      
Sbjct: 1172 PTTPAATPPSPKGGLATPS---------PKGAPTTPAATPPSPKGGLATPSPKG------ 1216

Query: 185  QDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPARED 244
                P    P P  G   P          +P     S KG PA      K  P  PA   
Sbjct: 1217 APTTPAATPPSPKGGLATP---SPKGAPTTPAATPPSPKGGPAT--PPPKGAPTPPAATP 1271

Query: 245  SENKDHAGEISSLPFPG----VVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300
               K   G +++ P  G     V+ P + +GGP  S                        
Sbjct: 1272 PSLK---GGLATPPHKGAPNPAVVTPPSPKGGPATS------------------------ 1304

Query: 301  QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKP 360
                 + TPPA  P +P                KG   +  PK  P PP  T    PP P
Sbjct: 1305 -PPKGAPTPPAATPPSP----------------KGSPGTPPPKGAPTPPAVT----PPSP 1343

Query: 361  NRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPP---PSH---PASQPPLPASHPSQP 414
               P +  T         S+  G T+ S+   P PP   PSH   PA  PP P   P+ P
Sbjct: 1344 KGTPTLPATT-------PSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 91/401 (22%), Positives = 119/401 (29%), Gaps = 62/401 (15%)

Query: 46   SPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTP-ASLTTRDPE 104
            SP  G +  P  G+P  P A  PS   K      PP   PT       +P   L T  P+
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSP--KGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192

Query: 105  AKVGFLKPVGPKP---INLPKEDSKPTFP--WPPGNK-----PSLHSVNQDHDLKPLGPK 154
                      P P   +  P     PT P   PP  K     PS           P  PK
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252

Query: 155  SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDES 214
             GP  P  +            +KG   +      P P    P   +  P ++        
Sbjct: 1253 GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTP 1312

Query: 215  PMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPG 274
            P     S KGSP       K  P  PA      K           P +     +S+GGP 
Sbjct: 1313 PAATPPSPKGSPGT--PPPKGAPTPPAVTPPSPKGT---------PTLPATTPSSKGGPT 1361

Query: 275  LSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEK 334
               + E         + K                 PA  P +P +       G +    K
Sbjct: 1362 TPSSKEGPTPPAATPSHKGG---------------PAMTPPSPKR-------GPAIPSPK 1399

Query: 335  GDKNSA-----TPKQKPLPPLFTLG----------PPPPKPNRPPNVDLTKFHKTSSGNS 379
            GD  S      +PK+ P  P+   G          PP   P        T   K      
Sbjct: 1400 GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP 1459

Query: 380  TSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
            +SKG  +    + PP P   PA +    +S P + P    P
Sbjct: 1460 SSKGDPTLPAVT-PPSPKEPPAPKQVATSSSPKKAPATPAP 1499


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 113/432 (26%), Positives = 151/432 (34%), Gaps = 40/432 (9%)

Query: 26  PNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKP 85
           P + S   AR++         P   PS  P+  +  P  +V  +SE     EP P   + 
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT-EPSPAARRR 227

Query: 86  TGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPG----NKPSLHS 141
             AG     PAS +       +      GP     P+  + P+ P P G      P +  
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 142 VNQDHD--LKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFG 199
             +D    L PL      TP  S   Q QA P L           Q   P PL P P+  
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPS 346

Query: 200 QKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRS--KSGPLKPAREDSENKDHAGEISSL 257
             P L T  S    +P    ++S GSP      S   S PL P          A  +  L
Sbjct: 347 APPSLQTLPS-PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405

Query: 258 PFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAP 317
             P     P AS     L+    +      +   +  F    +    A  +PPA  P +P
Sbjct: 406 QAPP---SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462

Query: 318 SKL-------TVGGPWGQ---SQEKEKGDKNSATPKQKPLPPLFTLGPP----PPKPNRP 363
           S         ++  P  Q   S         SATP  +  PPL    PP     P P  P
Sbjct: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKPPPQAP 520

Query: 364 PNVDLTKFHKTSSGNSTSKGQTSYS-TTSLP------PPPPSHPASQPPLPASHPSQPPV 416
           P +         S  ++  GQ  +S + SLP      PPP + P    PL    PS P  
Sbjct: 521 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 580

Query: 417 PSL-PPRNIKPP 427
           P+L  PR  +PP
Sbjct: 581 PTLQAPR--RPP 590



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 102/440 (23%), Positives = 153/440 (34%), Gaps = 64/440 (14%)

Query: 8   GNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVK 67
           G+P     V     RV G   ++G   RK L    G       P + P+ G    P    
Sbjct: 31  GSPRPPPPVTPAALRVLG---AAGAVGRKPLAERAGGIGGATIPESAPRAG----PTRSA 83

Query: 68  PSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLK------PVGPKPINLP 121
            +S   P   P       +G G+R   PA  T+  P +  G         P+G K + + 
Sbjct: 84  GTSSRNPASRPPA-----SGRGER-APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137

Query: 122 KEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFM 181
            E++          K S  S     D       SGPTP T       A  + +   G  +
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDT------SGPTPGTPS----PAMARRSRAAGTEV 187

Query: 182 SASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPL-KP 240
                       P+PA   +P   TE   +  S     S+++ SPA     S  G L +P
Sbjct: 188 G----------LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300
           A     +       S+ P         ++RG P    +  + K  + + A +    +   
Sbjct: 238 ASRSLSS-------SATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPR 289

Query: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPP--PP 358
           ++       PA  P + S L    P   + + +      ATP    L        P  PP
Sbjct: 290 KD-----AAPALGPLSSSPLATPSP-SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343

Query: 359 KPNRPPNVDLTKFHKTS--SGNSTSKGQ-TSYSTTSLPPPPPSHPASQPPLPASHPSQPP 415
            P+ PP++        +  S  +TS G  T  +T S  P PP  P + PP     P  PP
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-----PQAPP 398

Query: 416 VPSLPPRNIKPPFDLKSPVN 435
             +LPP    P      P++
Sbjct: 399 ALALPPLQAPPSPPASPPLS 418



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 84/395 (21%), Positives = 121/395 (30%), Gaps = 73/395 (18%)

Query: 25  GPNSSSGIQARKNLFNNQGNASP--PAGP---SNVPKFGSPKPPVAVKPSSEEKPDKEPK 79
           GP SSS +         Q  A P  PA P   S   +  +P P     PS+       P 
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356

Query: 80  PPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSL 139
           PP   P+ A    G+P    T        FL      P+  P   + P    PP   P  
Sbjct: 357 PPATPPSQATTSLGSPTLQATHS------FLPSPPLSPLATPPPQAPPALALPPLQAPPS 410

Query: 140 HSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFG 199
              +      PL P + P+P                      + +  L   P  P P+  
Sbjct: 411 PPASP-----PLSPLATPSPQAPN------------------ALAVHLLQAPFSPPPS-- 445

Query: 200 QKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPF 259
             PP+    S    SP  + S++  S AP                           SL  
Sbjct: 446 --PPVQAPFS-PPASPPVSPSATPPSQAP--------------------------PSLAA 476

Query: 260 PGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPAR-FPKAPS 318
           P + + P+     P         +    + A          Q   A  TPP +  P  P+
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 536

Query: 319 KLTVGGPWGQSQEKEKGDKNSATPKQKPL--PPLFTLGPPPPKPNRPPNVDLTKFHKTSS 376
                 P+  S         +  P+  P+   PL  +   PP P   P +   +   T  
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV---PPSPPASPTLQAPRRPPTPG 593

Query: 377 GNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHP 411
            +++  G     T +L P PP  P+  P    S P
Sbjct: 594 PDTSVSGPR--LTLALAPGPPPPPSRSPSSTLSGP 626


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 70.5 bits (171), Expect = 6e-12
 Identities = 94/342 (27%), Positives = 131/342 (38%), Gaps = 82/342 (23%)

Query: 189 PKPLFPKPAFGQKPPLSTENSHEDESPMKNVSS--SKGSPAPLGVRSKSGPLKPAREDSE 246
           P P  P P   + PP           PM +V S  S G     G    +GP+  AR    
Sbjct: 652 PPPEAPSPF--RAPPF------HPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPP 703

Query: 247 NK-DHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELA 305
              +H G    L  PG+V  P     GP   + G    ED  +                 
Sbjct: 704 TTANHLG----LSVPGLVSVPPRLLPGPENHRAGSN--EDPIL---------------AP 742

Query: 306 SGTPPARFPKAPSKLTVGG----PWGQSQEKEKGDK----------NSATPKQKPLPPLF 351
           SGTPP   P  P   T GG    P     +KE+             +S     + LPPL 
Sbjct: 743 SGTPP---PTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL- 798

Query: 352 TLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPP----PPSHPASQPPLP 407
              PPPP    PP +                  T   T S P P    P   PA+  PLP
Sbjct: 799 --PPPPPSGATPPPI----------------APTGPPTASPPVPAKEEPEELPAAPGPLP 840

Query: 408 ASHPSQPPVP---SLPPRNIKP---PFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGET 461
              P  PPVP   +LPP  + P   P     P  E++   +  +      DEE++ E E 
Sbjct: 841 PPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSS----DEEEEEEEEE 896

Query: 462 YEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKK 503
            E+ E  +E E+  E+EE+   E  ++E++E+E+ E+E +++
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 93/430 (21%), Positives = 147/430 (34%), Gaps = 145/430 (33%)

Query: 110 LKPVGPK---PINLPKEDSKPTF---PW-PPGNKPSLHSVNQDHDLKPLGP--------K 154
           L+P+GP    P  +P  ++   F   P+ PPG  PS+ S+     +   GP         
Sbjct: 638 LQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPS 697

Query: 155 SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDES 214
           + P PPT+ N    + P L  V            P  L P P            +H   S
Sbjct: 698 ARPGPPTTANHLGLSVPGLVSV------------PPRLLPGP-----------ENHRAGS 734

Query: 215 PMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGG-- 272
               + +  G+P P                                   + P  + GG  
Sbjct: 735 NEDPILAPSGTPPP----------------------------------TIPPDETFGGRV 760

Query: 273 --PGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQ 330
             P      +E+  D +I    ++  S +   E   G PP   P  PS            
Sbjct: 761 PRPAFVHYDKEEASDVEISLESDSDDSVVIVPE---GLPPLP-PPPPS------------ 804

Query: 331 EKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTT 390
                    ATP     PP+   GPP   P  P   +                +   +  
Sbjct: 805 --------GATP-----PPIAPTGPPTASPPVPAKEE--------------PEELPAAPG 837

Query: 391 SLPPPPPSHPASQPPLPASHPSQPPVPSLPPR------------------NIKPPFDLKS 432
            LPPPPP      PP P   P   P P L P                   NI    + + 
Sbjct: 838 PLPPPPP------PPPPVPGPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEE 891

Query: 433 PVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKE 492
              E+ ++     +   + +EE++ E E +E  E  +E E+  E+ E++  ELE++E++E
Sbjct: 892 EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFE--EEEEEEEEFEEEFEEEEGELEEEEEEE 949

Query: 493 KEKKEQEIKK 502
            E++E+E+++
Sbjct: 950 DEEEEEELEE 959



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 12/103 (11%)

Query: 347 LPPLFTLGP------PPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
           +PPL  +GP      P P P  P       FH      S     ++    S  P P + P
Sbjct: 635 VPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGP 694

Query: 401 ASQ----PPLPASH--PSQPPVPSLPPRNIKPPFDLKSPVNED 437
                  PP  A+H   S P + S+PPR +  P + ++  NED
Sbjct: 695 VPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737



 Score = 30.0 bits (66), Expect = 9.2
 Identities = 74/360 (20%), Positives = 111/360 (30%), Gaps = 76/360 (21%)

Query: 43   GNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKE-PKPPFLKPTGAGQRFGTPASLTTR 101
            G   PP  P+  P   +  PPV  K   EE P    P PP   P                
Sbjct: 805  GATPPPIAPTGPP---TASPPVPAKEEPEELPAAPGPLPPPPPP---------------- 845

Query: 102  DPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPT 161
                      P  P P+ LP     P      G  P+L     + DL  +   S      
Sbjct: 846  ---------PPPVPGPVTLPPPQLVPEGTPGGGGPPAL-----EEDLTVININSSDEEEE 891

Query: 162  SENEQKQAFPKLTGVKGKFMSASQD--------LEPKPLFPKPAFGQKPPLSTENSHEDE 213
             E E+++   +    +  F    +D         E +  F +    ++  L  E   EDE
Sbjct: 892  EEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDE 951

Query: 214  SPMKNVSS-------------SKGSPAPLGV-RSKSGPLKPAREDSENKDHAGEISSLPF 259
               + +                +G+P P  +  +   P  P +   E +   G +  +  
Sbjct: 952  EEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEE 1011

Query: 260  PGVV----LKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGT------- 308
            PG         A +     L   GE ++E     AA    Q  + +E  A  T       
Sbjct: 1012 PGTEEERGADTAPTLAPEALPSQGEVEREGES-PAAGPPPQELVEEEPSAPPTLLEEETE 1070

Query: 309  -------PPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPN 361
                   PP   P A  ++         QEKE+ D  +        PP     PPP +P+
Sbjct: 1071 DGSDKVQPPPETP-AEEEMETETEAEALQEKEQDDTAAMLADFIDCPPDDEKPPPPTEPD 1129


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 69.3 bits (168), Expect = 1e-11
 Identities = 112/450 (24%), Positives = 147/450 (32%), Gaps = 105/450 (23%)

Query: 24  TGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFL 83
           TG +S    +A+        +  PPA  +  P F S   P     +    P +EP     
Sbjct: 360 TGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAA 419

Query: 84  ---KPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKP--INLPKEDSKPTFPWPPGNKPS 138
              + +G  +R   P  L   +P AK     P GP P   N  +   +PTF W P     
Sbjct: 420 FGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPE---- 475

Query: 139 LHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAF 198
                         P   P  PT E+           +  +     ++   K LF +   
Sbjct: 476 --------------PCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLR--- 518

Query: 199 GQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGE-ISSL 257
             +P   TE   E  SP+ + SS     AP G  S+ G   P    S       E IS  
Sbjct: 519 --EPDSDTELQMEG-SPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPT 575

Query: 258 PFP----------GVVLKPAASRGGP------------GLSKNGEEKKEDRKIDAAKNTF 295
           P P          G+  +P    G P             L   G+      K+D  + + 
Sbjct: 576 PLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS 635

Query: 296 --QSKINQEELASG-------------TPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSA 340
               +I+ +E+ S              TP A    APS L    P               
Sbjct: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPL------------PP 683

Query: 341 TPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
            P   PLPP     PPPP+P  P    L                        PPPPP+HP
Sbjct: 684 PPGFPPLPP--PPPPPPPQPGFPMPPPLPP--------------------PPPPPPPAHP 721

Query: 401 A---SQPPLPASHPSQPPVPSLPPRNIKPP 427
           A     PPLPA  P  PP P LPP    PP
Sbjct: 722 AVTVPPPPLPAP-PGVPPPPILPPLPPFPP 750



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 76/335 (22%), Positives = 117/335 (34%), Gaps = 39/335 (11%)

Query: 94   TPASLTTRDPEAKVGFLKPVGPKPINLP-KEDSKPTFPWPPGNKPSLHSVNQDHDLKPLG 152
            TP  L  RDP+      +P  P  ++   +ED K +      +        ++ + +   
Sbjct: 1005 TPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDD 1064

Query: 153  PKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHED 212
                     SEN+ +     L+    K    S + E   +    A       S+E+S  +
Sbjct: 1065 DDDSDDRDESENDDEDT--ALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFE 1122

Query: 213  ESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGG 272
             S   + SSS+     +           ARE+ E ++    ++         +  AS G 
Sbjct: 1123 SSSESSPSSSEDEEEVV-----------AREEEEEEEEEEMVAE--------ESMASAGP 1163

Query: 273  PGLSKNGEEKK---EDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQS 329
                ++GEE         +D+     +  I  E +A    P+   + P  + V  P   S
Sbjct: 1164 EDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEP-ADS 1222

Query: 330  QE--KEKGDKNSATPKQKPLPPLFTLGPPPP-KPNRPPNVDLTKFHKTSSGNSTSKGQTS 386
            +E  +E G          P PP   +   PP  P R P  DL    +             
Sbjct: 1223 REPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL---- 1278

Query: 387  YSTTSLPPPPPSHPASQPPLP----ASHPSQPPVP 417
                 LPPP P  P S PP P    ASHPS PP P
Sbjct: 1279 --QPPLPPPRPPRPPSPPPEPETTDASHPSVPPEP 1311



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 96/437 (21%), Positives = 146/437 (33%), Gaps = 81/437 (18%)

Query: 61   KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTP----ASLTTRDPEAKVGFLKPVGPK 116
            +PP++ + + E   + EP+PP + P         P          +PE        V P+
Sbjct: 1251 RPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPE 1310

Query: 117  PI-------------NLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSE 163
            P+             +L K  S  T P  PG +P L   +    L      S P  P S 
Sbjct: 1311 PLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSL------SSPQVPGSP 1364

Query: 164  NEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPA---FGQKPPLSTENSHEDESPMKN-V 219
                   P L+   G   +  +D    P F +P+        PL T    E   P+ + V
Sbjct: 1365 FSYPAPSPSLSS-GGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPV 1423

Query: 220  SSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNG 279
                G P PL +        PA   ++ +      +  P P ++  P AS   P   K G
Sbjct: 1424 LLETGLPLPLPLPLPLPLALPAVLRAQAR------APTPLPPLLPAPLASCPPPMKRKPG 1477

Query: 280  EEKKEDRKI-----DAAKNTFQSKINQEELASGTPPAR--FPKAPSKLTVGGPWGQSQEK 332
              ++    +        +    + + +E L     P    FP      TV   +      
Sbjct: 1478 RPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDF------ 1531

Query: 333  EKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSL 392
                +N+  P   P PP   L P PP P  PP V+ TK       N        + + ++
Sbjct: 1532 ----RNAGIP--APPPP---LPPQPPPPPPPPPVEPTKLPFKELDN-------QWPSEAI 1575

Query: 393  PPPPPSH---------------PASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNED 437
            PP P                  P  +PP        PP  S     + PP  L  P +E 
Sbjct: 1576 PPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGS---PELSPPQPLFRPRSEF 1632

Query: 438  NQDGVTHSDGAGNLDEE 454
             +  + +    G +DEE
Sbjct: 1633 EEMTILYDIWNGGIDEE 1649



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 37/190 (19%), Positives = 74/190 (38%), Gaps = 51/190 (26%)

Query: 567  VEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQSGSGGIFPPPPDDDIYD 626
            +E+D    + +K+SL       E+++E  ++  E+DD                 DDD  D
Sbjct: 1027 LELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDD-----------------DDDDSD 1069

Query: 627  GIEEEDADDGSTL--QVQEKSNTWSWGILKMLKGKDDRKKSI----REKPKVSDSDNNEG 680
              +E + DD  T   +  EK            +G  D ++++     +    S S+++E 
Sbjct: 1070 DRDESENDDEDTALSEASEKD-----------EGDSDEEETVSIVTSKAEATSSSESSES 1118

Query: 681  SSFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNVGKAKTEEKDLKKLKKQEKEEKD 740
            S F +  +      E  ++V                 V + + EE++ +++  +E     
Sbjct: 1119 SEFESSSESSPSSSEDEEEV-----------------VAREEEEEEEEEEMVAEESMASA 1161

Query: 741  FRKKFKYDGE 750
              + F+ DGE
Sbjct: 1162 GPEDFEQDGE 1171



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 16/73 (21%), Positives = 34/73 (46%)

Query: 427  PFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELE 486
            P +L S   ED ++ ++    +   +EE + E E  +D +   +   + E +++     E
Sbjct: 1026 PLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSE 1085

Query: 487  KKEQKEKEKKEQE 499
              E+ E +  E+E
Sbjct: 1086 ASEKDEGDSDEEE 1098


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 105/402 (26%), Positives = 141/402 (35%), Gaps = 58/402 (14%)

Query: 43  GNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
           G AS   GP+   +   P  P++V  SS       P  P   P G G     P       
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISV--SSSGASGAPPTKPPTTPVGGGNLPSAPPPANF-- 294

Query: 103 PEAKVGFLKPVGPKPINLPKEDSKPTFPWP-PGNKPSLHSVNQDHDLKPLGPKSGPT--- 158
           P        P   +P+N            P PG+ PS H++ Q     P GP+ GPT   
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP 354

Query: 159 -----PPTSEN--EQKQAFP------KLTGVKGKFMSASQDLEPKP---LFPKPAFGQKP 202
                PP S +       FP                S+S    P P     P       P
Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414

Query: 203 PLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP--AREDSENKDHAGEISSLPFP 260
           P S   S++   P K    S  S A   V S+  P  P   R  + +  H G     PFP
Sbjct: 415 PTSLSVSNQ---PPKYTQPSLPSQA---VWSQGPPPPPPYGRLLANSNAHPG-----PFP 463

Query: 261 GVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKL 320
                 A S   P +S +    ++ ++    +   Q +  Q    SG PP          
Sbjct: 464 PST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP---------- 511

Query: 321 TVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNR--PPNVDLTKFHKTSSGN 378
               P       E G  + A P     P L +L P PP P    PP+  ++      +G 
Sbjct: 512 ----PGAFPHPLEGGSSHHAHPYAMS-PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP 566

Query: 379 STSKGQTSYSTTSLPPPPPSHPA-SQPPLPASHPSQPPVPSL 419
             S    S S+TS    P SHP+ SQ P  A +P  PPVP++
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-PPVPTV 607



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 117/522 (22%), Positives = 176/522 (33%), Gaps = 74/522 (14%)

Query: 42  QGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTR 101
           QG    P GP   P       P ++ P+S   P    + P+   + +     + +S ++ 
Sbjct: 337 QGMGGLPPGPEKGPTLAPS--PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394

Query: 102 D----------PEAKVGFLKPVGPKPINLPKEDSKPTFP----WPPGNKP----SLHSVN 143
                      P     F  P      N P + ++P+ P    W  G  P         N
Sbjct: 395 SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454

Query: 144 QDHDLKPLGPKSGPT----PPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFG 199
            +    P  P +G      PP S +       +    + +     Q        P P   
Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA 514

Query: 200 QKPPLSTENSHEDESPMKNVSSSKGSPAPLGVR-----------SKSGPLKPAREDSENK 248
              PL   +SH       + S     P P G             S++GP  P    S N 
Sbjct: 515 FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNS 574

Query: 249 DHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGT 308
             +    S P       P+ S+G  G               A  +T  + +      +G 
Sbjct: 575 SSSTSQGSYPCS----HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP--AGY 628

Query: 309 PPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKP-LPPLFTLGPPPPKPNRPPNVD 367
             A  P  P       P+G+        K +  P  KP  PP F  G PP      P   
Sbjct: 629 KTASPPGPP-------PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681

Query: 368 LTKFHKTSSGNSTSKGQTSYSTTSLP--PPPPSHPASQPPLPASHPSQPPV--------P 417
              F K  S             + LP  PPPP+ PAS PPL A+   Q P         P
Sbjct: 682 PGTF-KPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740

Query: 418 SLPPRNIKPP---FDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKER--- 471
             P R+  PP    D+ S  ++  +    H D   N     D      E  + +K+R   
Sbjct: 741 VPPARSPSPPPKVVDVPSHASQSARFN-KHLDRGFNSCARSDLYFVPLEGSKLAKKRADL 799

Query: 472 --EKKREKEEKKRLELEKKEQKEKEK-----KEQEIKKKFKL 506
             + +RE E++ R E E++ ++E+EK     KE+E+++  KL
Sbjct: 800 VEKVRREAEQRAREEKEREREREREKEREREKERELERSVKL 841



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 94/427 (22%), Positives = 130/427 (30%), Gaps = 84/427 (19%)

Query: 7   GGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAV 66
           G +   D+  ++R    T P+  S      +  ++ G +  PA P + P    P P    
Sbjct: 117 GSSDPRDIDQDNRS---TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP---- 169

Query: 67  KPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSK 126
                + PD  P+ P              AS          G+  P+ P     P     
Sbjct: 170 -----QPPDSTPRQP-------------EASFEPHPSVTPTGYHAPMEP-----PTSRMF 206

Query: 127 PTFPWPPGNKPSLHSVNQDHDLK--PLGPKSGPTPPT--SENEQKQAFPKLTGVKGKFMS 182
              P  P   P L+       L   P+GPK G    +    N  KQ  P  T +      
Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266

Query: 183 ASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAR 242
           AS     KP           P+   N      P      +   P P  +R    PL  A 
Sbjct: 267 ASGAPPTKP--------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR----PLNNAS 314

Query: 243 EDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQE 302
                      + + P PG +  P A   G G    G EK                +   
Sbjct: 315 ASPPG------LGAQPLPGHLPSPHAMGQGMGGLPPGPEK------GPTLAPSPHSLPPA 362

Query: 303 ELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPK--- 359
             ++  PP RFP + S  +       S         S  P  + LP      PPP     
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAA--ASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420

Query: 360 PNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPP---------SHPASQPP-LPAS 409
            N+PP     K+ + S  +     Q        PPPPP         +HP   PP   A 
Sbjct: 421 SNQPP-----KYTQPSLPSQAVWSQ------GPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469

Query: 410 HPSQPPV 416
             + PPV
Sbjct: 470 STAHPPV 476



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 35/132 (26%), Positives = 43/132 (32%), Gaps = 31/132 (23%)

Query: 324 GPWGQSQEKEKGDKNSATPKQKPLPPLFTL-----GPPPPKPNRPPNVDLTKFHKTSSGN 378
           GP G       G  N       P  P+        G PP KP   P            GN
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTP---------VGGGN 284

Query: 379 STSKGQTS---YSTTSLPPPPPSHP----ASQPP----------LPASHPSQPPVPSLPP 421
             S    +   + T +LPPPP   P    ++ PP          LP+ H     +  LPP
Sbjct: 285 LPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344

Query: 422 RNIKPPFDLKSP 433
              K P    SP
Sbjct: 345 GPEKGPTLAPSP 356


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 105/402 (26%), Positives = 141/402 (35%), Gaps = 58/402 (14%)

Query: 43  GNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
           G AS   GP+   +   P  P++V  SS       P  P   P G G     P       
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISV--SSSGASGAPPTKPPTTPVGGGNLPSAPPPANF-- 294

Query: 103 PEAKVGFLKPVGPKPINLPKEDSKPTFPWP-PGNKPSLHSVNQDHDLKPLGPKSGPT--- 158
           P        P   +P+N            P PG+ PS H++ Q     P GP+ GPT   
Sbjct: 295 PHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAP 354

Query: 159 -----PPTSEN--EQKQAFP------KLTGVKGKFMSASQDLEPKP---LFPKPAFGQKP 202
                PP S +       FP                S+S    P P     P       P
Sbjct: 355 SPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPP 414

Query: 203 PLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP--AREDSENKDHAGEISSLPFP 260
           P S   S++   P K    S  S A   V S+  P  P   R  + +  H G     PFP
Sbjct: 415 PTSLSVSNQ---PPKYTQPSLPSQA---VWSQGPPPPPPYGRLLANSNAHPG-----PFP 463

Query: 261 GVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKL 320
                 A S   P +S +    ++ ++    +   Q +  Q    SG PP          
Sbjct: 464 PST--GAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPP---------- 511

Query: 321 TVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNR--PPNVDLTKFHKTSSGN 378
               P       E G  + A P     P L +L P PP P    PP+  ++      +G 
Sbjct: 512 ----PGAFPHPLEGGSSHHAHPYAMS-PSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGP 566

Query: 379 STSKGQTSYSTTSLPPPPPSHPA-SQPPLPASHPSQPPVPSL 419
             S    S S+TS    P SHP+ SQ P  A +P  PPVP++
Sbjct: 567 PVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF-PPVPTV 607



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 117/522 (22%), Positives = 176/522 (33%), Gaps = 74/522 (14%)

Query: 42  QGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTR 101
           QG    P GP   P       P ++ P+S   P    + P+   + +     + +S ++ 
Sbjct: 337 QGMGGLPPGPEKGPTLAPS--PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSS 394

Query: 102 D----------PEAKVGFLKPVGPKPINLPKEDSKPTFP----WPPGNKP----SLHSVN 143
                      P     F  P      N P + ++P+ P    W  G  P         N
Sbjct: 395 SASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454

Query: 144 QDHDLKPLGPKSGPT----PPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFG 199
            +    P  P +G      PP S +       +    + +     Q        P P   
Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGA 514

Query: 200 QKPPLSTENSHEDESPMKNVSSSKGSPAPLGVR-----------SKSGPLKPAREDSENK 248
              PL   +SH       + S     P P G             S++GP  P    S N 
Sbjct: 515 FPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNS 574

Query: 249 DHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGT 308
             +    S P       P+ S+G  G               A  +T  + +      +G 
Sbjct: 575 SSSTSQGSYPCS----HPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP--AGY 628

Query: 309 PPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKP-LPPLFTLGPPPPKPNRPPNVD 367
             A  P  P       P+G+        K +  P  KP  PP F  G PP      P   
Sbjct: 629 KTASPPGPP-------PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAG 681

Query: 368 LTKFHKTSSGNSTSKGQTSYSTTSLP--PPPPSHPASQPPLPASHPSQPPV--------P 417
              F K  S             + LP  PPPP+ PAS PPL A+   Q P         P
Sbjct: 682 PGTF-KPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESP 740

Query: 418 SLPPRNIKPP---FDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKER--- 471
             P R+  PP    D+ S  ++  +    H D   N     D      E  + +K+R   
Sbjct: 741 VPPARSPSPPPKVVDVPSHASQSARFN-KHLDRGFNSCARSDLYFVPLEGSKLAKKRADL 799

Query: 472 --EKKREKEEKKRLELEKKEQKEKEK-----KEQEIKKKFKL 506
             + +RE E++ R E E++ ++E+EK     KE+E+++  KL
Sbjct: 800 VEKVRREAEQRAREEKEREREREREKEREREKERELERSVKL 841



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 94/427 (22%), Positives = 130/427 (30%), Gaps = 84/427 (19%)

Query: 7   GGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAV 66
           G +   D+  ++R    T P+  S      +  ++ G +  PA P + P    P P    
Sbjct: 117 GSSDPRDIDQDNRS---TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP---- 169

Query: 67  KPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSK 126
                + PD  P+ P              AS          G+  P+ P     P     
Sbjct: 170 -----QPPDSTPRQP-------------EASFEPHPSVTPTGYHAPMEP-----PTSRMF 206

Query: 127 PTFPWPPGNKPSLHSVNQDHDLK--PLGPKSGPTPPT--SENEQKQAFPKLTGVKGKFMS 182
              P  P   P L+       L   P+GPK G    +    N  KQ  P  T +      
Sbjct: 207 QAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSG 266

Query: 183 ASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAR 242
           AS     KP           P+   N      P      +   P P  +R    PL  A 
Sbjct: 267 ASGAPPTKP--------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR----PLNNAS 314

Query: 243 EDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQE 302
                      + + P PG +  P A   G G    G EK                +   
Sbjct: 315 ASPPG------LGAQPLPGHLPSPHAMGQGMGGLPPGPEK------GPTLAPSPHSLPPA 362

Query: 303 ELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPK--- 359
             ++  PP RFP + S  +       S         S  P  + LP      PPP     
Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAA--ASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSV 420

Query: 360 PNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPP---------SHPASQPP-LPAS 409
            N+PP     K+ + S  +     Q        PPPPP         +HP   PP   A 
Sbjct: 421 SNQPP-----KYTQPSLPSQAVWSQ------GPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469

Query: 410 HPSQPPV 416
             + PPV
Sbjct: 470 STAHPPV 476



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 35/132 (26%), Positives = 43/132 (32%), Gaps = 31/132 (23%)

Query: 324 GPWGQSQEKEKGDKNSATPKQKPLPPLFTL-----GPPPPKPNRPPNVDLTKFHKTSSGN 378
           GP G       G  N       P  P+        G PP KP   P            GN
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTP---------VGGGN 284

Query: 379 STSKGQTS---YSTTSLPPPPPSHP----ASQPP----------LPASHPSQPPVPSLPP 421
             S    +   + T +LPPPP   P    ++ PP          LP+ H     +  LPP
Sbjct: 285 LPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344

Query: 422 RNIKPPFDLKSP 433
              K P    SP
Sbjct: 345 GPEKGPTLAPSP 356


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 103/439 (23%), Positives = 153/439 (34%), Gaps = 84/439 (19%)

Query: 8   GNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVK 67
           G+P     V     RV G   ++G   RK L    G       P + P+ G    P    
Sbjct: 31  GSPRPPPPVTPAALRVLG---AAGAVGRKPLAERAGGIGGATIPESAPRAG----PTRSA 83

Query: 68  PSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLK------PVGPKPINLP 121
            +S   P   P       +G G+R   PA  T+  P +  G         P+G K + + 
Sbjct: 84  GTSSRNPASRPPA-----SGRGER-APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137

Query: 122 KEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFM 181
            E++          K S  S     D       SGPTP T       A  + +   G  +
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDT------SGPTPGTPS----PAMARRSRAAGTEV 187

Query: 182 SASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPL-KP 240
                       P+PA   +P   TE   +  S     S+++ SPA     S  G L +P
Sbjct: 188 G----------LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237

Query: 241 AREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKIN 300
           A     +       S+ P         ++RG P    +  + K  + + A +    +   
Sbjct: 238 ASRSLSS-------SATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQVTPPR 289

Query: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPP---- 356
           ++       PA  P + S L    P G          N+ATP    LPP   L  P    
Sbjct: 290 KD-----AAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLA 344

Query: 357 PPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ--P 414
           PP P+ PP++                        +LP PP + P+  PP   + P Q  P
Sbjct: 345 PPSPSAPPSLQ-----------------------TLPSPPATPPSQAPPSMTTPPMQAPP 381

Query: 415 PVPSLPPRNIKPPFDLKSP 433
            + ++PP  I+ P  L SP
Sbjct: 382 SLQTIPP--IQVPHSLTSP 398



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 99/414 (23%), Positives = 129/414 (31%), Gaps = 50/414 (12%)

Query: 42  QGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPF----LKPTGAGQRFGTPAS 97
           +G    PA PS  PK   PK   A++P     P K+  P        P       GT A 
Sbjct: 260 RGTPRAPAHPSQ-PK---PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315

Query: 98  LTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPL-GPKSG 156
                  A       + P P   P     P  P  P   PSL ++       P   P S 
Sbjct: 316 PVPPPDNAATPLPATLPPSP---PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 157 PTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQ----KPPLSTENSHED 212
            TPP       Q  P +  V     S S    P PL             P L   +S   
Sbjct: 373 TTPPMQAPPSLQTIPPIQ-VPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431

Query: 213 ESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGG 272
            SP +  +S      P      S PL+              + + P     L PA S   
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLS----------LPASPPLQTSLSPAVSPLS 481

Query: 273 PGLSKNGEEKKEDRKIDAAKNTFQSKINQE-ELASGTPPARFPKAPSKLTVGGPWGQSQE 331
             L+ +  +        + +    S I    E  S   P      P+ LT       +  
Sbjct: 482 SPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT-------TPP 534

Query: 332 KEKGDKNSATPKQKPLPPLFTLG---PPPPKP---NRPPNVDLTKFHKTSSGNSTSKGQT 385
            E     +  P Q    PL T     PP P P     PP+   T   +T S  +T   Q 
Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594

Query: 386 SYSTTSLP----PPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVN 435
             +  S P    P PP  P + PP     P  PP  +LPP    P      P++
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPP-----PQAPPXLALPPLQAPPSPPASPPLS 643



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 83/333 (24%), Positives = 108/333 (32%), Gaps = 46/333 (13%)

Query: 45   ASPPAGPSNVPKFGSP----KPPVAVKPSSEEKPDKEPK---PPFLKPTGAGQRFGTPAS 97
            ASPP  PS  P   +P     PP+ V PS    P   P    PP + P  A      P S
Sbjct: 712  ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPS 771

Query: 98   LTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGP 157
                 P + +    P  P  +  P   + P+   PP + P     +    L P+ P + P
Sbjct: 772  PPASLPMSPLAKPPPQAPPALATPPLQALPS---PPASFPGQAPFSPSASL-PMSPLATP 827

Query: 158  TPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKP-------------AFGQKPPL 204
             P   +     A P L        S +     +P  P P             A G  PP 
Sbjct: 828  PP---QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884

Query: 205  STENSHEDESPMKNVSSSKGSPAPLGVRS-KSGP-----LKPAREDSENKDHAGEISSLP 258
            S   S     P     SS  +  P  +R   SGP       P  +      H    S  P
Sbjct: 885  SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 944

Query: 259  FPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTP-PARFPKAP 317
             P     P A RG PG              D     +++    E   S TP P      P
Sbjct: 945  AP-----PLAFRGAPGAPLPWPPATGPGSADGLCTIYET----EGPESATPAPGALDPGP 995

Query: 318  SKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPL 350
            S  T G   G++        +S +PKQ  L  L
Sbjct: 996  SPGTSG---GKAAAGAGAGASSRSPKQARLGEL 1025



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 99/441 (22%), Positives = 135/441 (30%), Gaps = 57/441 (12%)

Query: 18  SRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKP-----SSEE 72
           SRP   + P  S  +QA  +L      ASPP   S  P       P+ + P     S   
Sbjct: 445 SRP--ASTPPDSPPLQAPLSL-----PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 73  KPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWP 132
              + P    + P    Q    P SL T              P  +  P  ++ P+   P
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTP-------------PASLTTPPLENLPSLAPP 544

Query: 133 PGNKPSLHSVNQDHDLKPL-------GPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQ 185
           P    S        +  P         P S  T P  E     A P             Q
Sbjct: 545 PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQ 604

Query: 186 DLEPKPLFP-------KPAFGQKPPLSTENSHEDESPMKNVSS-SKGSPAPLGVRSKSGP 237
            L   PL P        P     PPL    S     P+  +++ S  +P  L V     P
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664

Query: 238 LKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQS 297
             P          +   S    P        S+  P L+    +           +   +
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSAT---PPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721

Query: 298 KINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPP 357
              Q       PP + P +P       P   +         +A P Q P  P  +L   P
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSP-SATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780

Query: 358 ---PKPNRPPNVDLTKFHKTSSGNSTSKGQTSYS-TTSLP------PPPPSHPASQPPLP 407
              P P  PP +         S  ++  GQ  +S + SLP      PPP + P    PL 
Sbjct: 781 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 840

Query: 408 ASHPSQPPVPSL-PPRNIKPP 427
              PS P  P+L  PR  +PP
Sbjct: 841 QVPPSPPASPTLQAPR--RPP 859



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 75/297 (25%), Positives = 97/297 (32%), Gaps = 25/297 (8%)

Query: 151 LGPKSGPTPPTS------ENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPL 204
           L P S  TPP S      EN    A P L        +   +  P P  P P      PL
Sbjct: 518 LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPL 576

Query: 205 ST---ENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG 261
           +T   E      +P      +  SP   G+ S   PL P    +     A    +LP   
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSP--PLSPL---ATPPPQAPPXLALPPLQ 631

Query: 262 VVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
               P AS     L+    +      +   +  F    +    A  +PPA  P +PS   
Sbjct: 632 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT- 690

Query: 322 VGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRP---PNVDLTKFHKTSSGN 378
              P  Q+            P     PP+     PPP+   P   P + +      S   
Sbjct: 691 ---PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPM 747

Query: 379 STSKGQTSYSTTSLPPPPPSHPASQPP-LPASHPSQPPVPSLPPRNIKPPFD-LKSP 433
           S S          L  PP   P S P  LP S  ++PP P  PP    PP   L SP
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP-PQAPPALATPPLQALPSP 803



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 80/371 (21%), Positives = 115/371 (30%), Gaps = 43/371 (11%)

Query: 48  PAGPSNVPKFGSPKP---PVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPE 104
           P  P+  P    P P   P    PSS   P  +  P    P   G      + L T  P+
Sbjct: 561 PPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620

Query: 105 AKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLK-PLGPKSGPTPPTSE 163
           A      P    P + P          P    P+  +V   H L+ P  P   P+PP   
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAV---HLLQAPFSPP--PSPPVQA 675

Query: 164 NEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSK 223
                A P ++        A   L   PL   P+    PP+S   +   ++P    +   
Sbjct: 676 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-- 733

Query: 224 GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKK 283
               PL V        P    +        + + P   V   P AS     L+K      
Sbjct: 734 ----PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP--- 786

Query: 284 EDRKIDAAKNTFQSKINQEELASGTPPAR-FPKAPSKLTVGGPWGQSQEKEKGDKNSATP 342
                            Q   A  TPP +  P  P+      P+  S         +  P
Sbjct: 787 -----------------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 343 KQKPL--PPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
           +  P+   PL  +   PP P   P +   +   T   +++  G     T +L P PP  P
Sbjct: 830 QAPPVLAAPLLQV---PPSPPASPTLQAPRRPPTPGPDTSVSGPR--LTLALAPGPPPPP 884

Query: 401 ASQPPLPASHP 411
           +  P    S P
Sbjct: 885 SRSPSSTLSGP 895



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 76/331 (22%), Positives = 103/331 (31%), Gaps = 57/331 (17%)

Query: 47   PPAGPSNVPKFGSPKPPVAVKPSSEEKP-DKEPKPPFLKPTG--------AGQRFGTPAS 97
            PP+ P++ P   S  PP  V P     P    P PP   P          A     TP  
Sbjct: 738  PPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPL 797

Query: 98   LTTRDPEAKVGFLKPVGP------KPINLPKEDSKPTFPWP-------PGNKPSLHSVNQ 144
                 P A      P  P       P+  P   + P    P       P   P+L +  +
Sbjct: 798  QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 857

Query: 145  ----DHDLKPLGPK------SGPTPPTSENEQKQ-AFPKLTGVKGKFMSASQDLEPKPLF 193
                  D    GP+       GP PP S +     + P L G      S  ++L      
Sbjct: 858  PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917

Query: 194  PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSG---PLKPAREDSENK-- 248
            P+      PP   E      +     + S+G   PL  R   G   P  PA         
Sbjct: 918  PEGGAAASPPPDAE-----LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 972

Query: 249  ----DHAGEISSLPFPGVVLKPAASRG--------GPGLSKNGEEKKEDRKIDAAKNTFQ 296
                +  G  S+ P PG  L P  S G        G G   +    K+ R  +      Q
Sbjct: 973  CTIYETEGPESATPAPG-ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ 1031

Query: 297  SKINQEELASGTPPARFPKAPSKLTVGGPWG 327
            + + Q  L S T      +  +  + GGP G
Sbjct: 1032 ASVVQ-HLLSRTLLLAAAEGAAGGSGGGPGG 1061


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 95/378 (25%), Positives = 137/378 (36%), Gaps = 65/378 (17%)

Query: 35  RKNLFNNQGNASPPAGPSNVPKFGSP----KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQ 90
           R ++ +   +  PP   +  P   SP     PPV   P    +P   P PP   P   G 
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV---PGGPRQPSPGPTPPPF-PGNRGT 228

Query: 91  RFG----TPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPP-GNKPSLHSVNQD 145
             G      + L++  P +    L P   + +     D KP  P PP GN+PS+H     
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL-----DDKPPPPPPPVGNRPSIH----- 278

Query: 146 HDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLS 205
            +  P      P PP +      + P+         SAS    P P  P P+    PPL 
Sbjct: 279 REAVP------PPPPQNNKPPVPSTPR--------PSASSQAPPPP--PPPSRPGPPPLP 322

Query: 206 TENSHEDES---PMKNVSSSKGSPAPLGVRSKSGPLKP---AREDSENKDHAGEISSLPF 259
             +S  DE+   P +N+S S  +P PL    +SGPL P    R     +D  G    LP 
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTP-PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381

Query: 260 PGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSK 319
           P            P +S+NG      R + A      S+   +   SG  P   P  P +
Sbjct: 382 P------------PPVSRNG---STSRALPATPQ-LPSRSGVDSPRSGPRP---PLPPDR 422

Query: 320 LTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNS 379
            + G P          +    +P +      F   P    P   P V  TK + +    +
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARN 482

Query: 380 TSKGQTSYSTTSLPPPPP 397
            S+  ++      PP PP
Sbjct: 483 ESRSGSNRRERGAPPLPP 500



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/311 (25%), Positives = 107/311 (34%), Gaps = 86/311 (27%)

Query: 132 PPG-------NKPSLHSV-NQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSA 183
           PPG         P L S  N+D+D    G +    PP   +   + F   +G  G+F   
Sbjct: 97  PPGLGGLFQAGMPKLRSTANRDNDSG--GSRPPLLPPGGRSTSAKPFSPPSG-PGRFPVP 153

Query: 184 S---QDLEPKPLF-----PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSP-APLGVRSK 234
           S   +   P+P       P+P  G KP            P+++   ++GSP  P G R  
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP 213

Query: 235 S-GPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKN 293
           S GP  P                 PFPG       + GG  +                  
Sbjct: 214 SPGPTPP-----------------PFPG---NRGTALGGGSIR----------------- 236

Query: 294 TFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL 353
             QS ++     S  PP   P  PS+     P         G++ S   +  P       
Sbjct: 237 --QSPLSSSSPFSNRPP--LPPTPSRALDDKP--PPPPPPVGNRPSIHREAVP------- 283

Query: 354 GPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ 413
            PPPP+ N+PP                S  + S S+ + PPPPP      PPLP S    
Sbjct: 284 -PPPPQNNKPP--------------VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 414 PPVPSLPPRNI 424
              P LP RN+
Sbjct: 329 DETPRLPQRNL 339



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 58/235 (24%), Positives = 85/235 (36%), Gaps = 31/235 (13%)

Query: 45  ASPPAGPSN--VPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
           A PP  P N   P   +P+P  + +      P   P PP L P+ +G         T R 
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN------DETPRL 334

Query: 103 PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTS 162
           P+  +       P    LP        P PP  +P     +      PL P   P P + 
Sbjct: 335 PQRNLSLSSSTPP----LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP---PPPVSR 387

Query: 163 ENEQKQAFPKLTGVKGKFMSASQDLEPKPLFP--KPAFGQKPP----LSTENSHEDESPM 216
                +A P    +  +    S    P+P  P  +P+ G  PP     S  N  +D SP 
Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD-SPC 446

Query: 217 KNVSSSK---------GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGV 262
           ++   S+           P P    +KS P K AR +S +  +  E  + P P +
Sbjct: 447 EDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 92/382 (24%), Positives = 128/382 (33%), Gaps = 80/382 (20%)

Query: 58  GSPKPPVAVKP--SSEEKPDKEPKPPFLKPTGA-GQRFGTPASLTTRDPEAKVGFLKPVG 114
           G  +PP+      S+  KP   P  P   P  + G R G P     R P  +      VG
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR----PDVG 177

Query: 115 PKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKS---GPTPPTSENEQKQAFP 171
            KP ++P     P+ P P  + P     N+     P GP+    GPTPP         FP
Sbjct: 178 SKPDSIPPP--VPSTPRPIQSSPH----NRGSPPVPGGPRQPSPGPTPPP--------FP 223

Query: 172 KLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHE-DESPMKNVSSSKGSPAPLG 230
              G +G  +     +   PL     F  +PPL    S   D+ P          P P  
Sbjct: 224 ---GNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRALDDKP---------PPPPPP 270

Query: 231 VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLK-----PAASRGGPGLSKNGEEKKED 285
           V ++    + A      +++   + S P P    +     P  SR GP          ++
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 286 RKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQK 345
                 +N          L+S TPP   P     L                     P ++
Sbjct: 331 TPRLPQRNL--------SLSSSTPPLPSPGRSGPLP------------------PPPSER 364

Query: 346 PLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPP 405
           P PP+    PP      PP   +++   TS     +    S S    P   P     +PP
Sbjct: 365 PPPPV--RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP-----RPP 417

Query: 406 LPASHPS----QPPVPSLPPRN 423
           LP   PS     PP PS   RN
Sbjct: 418 LPPDRPSAGAPPPPPPSTSIRN 439



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/258 (23%), Positives = 86/258 (33%), Gaps = 66/258 (25%)

Query: 224 GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG---VVLKPAASRGGPGL----- 275
           G P  LG   ++G  K     + + D  G    L  PG      KP +   GPG      
Sbjct: 95  GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154

Query: 276 --SKNGEEKKEDRKIDAAKNTFQSK--------------INQEELASGTPPARF-PKAPS 318
              ++G  + +  ++   +    SK              I       G+PP    P+ PS
Sbjct: 155 PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214

Query: 319 KLTVGGPW---------GQSQEKEKGDKNSATPKQKPLPP-----LFTLGPPPPKP--NR 362
                 P+         G S  +     +S    + PLPP     L    PPPP P  NR
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274

Query: 363 PPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH---PASQPPLPASHPSQPPVPSL 419
           P                      S    ++PPPPP +   P    P P++    PP P  
Sbjct: 275 P----------------------SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312

Query: 420 PPRNIKPPFDLKSPVNED 437
           P R   PP    S  N++
Sbjct: 313 PSRPGPPPLPPSSSGNDE 330


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 95/378 (25%), Positives = 137/378 (36%), Gaps = 65/378 (17%)

Query: 35  RKNLFNNQGNASPPAGPSNVPKFGSP----KPPVAVKPSSEEKPDKEPKPPFLKPTGAGQ 90
           R ++ +   +  PP   +  P   SP     PPV   P    +P   P PP   P   G 
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV---PGGPRQPSPGPTPPPF-PGNRGT 228

Query: 91  RFG----TPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPP-GNKPSLHSVNQD 145
             G      + L++  P +    L P   + +     D KP  P PP GN+PS+H     
Sbjct: 229 ALGGGSIRQSPLSSSSPFSNRPPLPPTPSRAL-----DDKPPPPPPPVGNRPSIH----- 278

Query: 146 HDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLS 205
            +  P      P PP +      + P+         SAS    P P  P P+    PPL 
Sbjct: 279 REAVP------PPPPQNNKPPVPSTPR--------PSASSQAPPPP--PPPSRPGPPPLP 322

Query: 206 TENSHEDES---PMKNVSSSKGSPAPLGVRSKSGPLKP---AREDSENKDHAGEISSLPF 259
             +S  DE+   P +N+S S  +P PL    +SGPL P    R     +D  G    LP 
Sbjct: 323 PSSSGNDETPRLPQRNLSLSSSTP-PLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP 381

Query: 260 PGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSK 319
           P            P +S+NG      R + A      S+   +   SG  P   P  P +
Sbjct: 382 P------------PPVSRNG---STSRALPATPQ-LPSRSGVDSPRSGPRP---PLPPDR 422

Query: 320 LTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNS 379
            + G P          +    +P +      F   P    P   P V  TK + +    +
Sbjct: 423 PSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARN 482

Query: 380 TSKGQTSYSTTSLPPPPP 397
            S+  ++      PP PP
Sbjct: 483 ESRSGSNRRERGAPPLPP 500



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 78/311 (25%), Positives = 107/311 (34%), Gaps = 86/311 (27%)

Query: 132 PPG-------NKPSLHSV-NQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSA 183
           PPG         P L S  N+D+D    G +    PP   +   + F   +G  G+F   
Sbjct: 97  PPGLGGLFQAGMPKLRSTANRDNDSG--GSRPPLLPPGGRSTSAKPFSPPSG-PGRFPVP 153

Query: 184 S---QDLEPKPLF-----PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSP-APLGVRSK 234
           S   +   P+P       P+P  G KP            P+++   ++GSP  P G R  
Sbjct: 154 SPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP 213

Query: 235 S-GPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKN 293
           S GP  P                 PFPG       + GG  +                  
Sbjct: 214 SPGPTPP-----------------PFPG---NRGTALGGGSIR----------------- 236

Query: 294 TFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL 353
             QS ++     S  PP   P  PS+     P         G++ S   +  P       
Sbjct: 237 --QSPLSSSSPFSNRPP--LPPTPSRALDDKP--PPPPPPVGNRPSIHREAVP------- 283

Query: 354 GPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ 413
            PPPP+ N+PP                S  + S S+ + PPPPP      PPLP S    
Sbjct: 284 -PPPPQNNKPP--------------VPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN 328

Query: 414 PPVPSLPPRNI 424
              P LP RN+
Sbjct: 329 DETPRLPQRNL 339



 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 58/235 (24%), Positives = 85/235 (36%), Gaps = 31/235 (13%)

Query: 45  ASPPAGPSN--VPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
           A PP  P N   P   +P+P  + +      P   P PP L P+ +G         T R 
Sbjct: 281 AVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGN------DETPRL 334

Query: 103 PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTS 162
           P+  +       P    LP        P PP  +P     +      PL P   P P + 
Sbjct: 335 PQRNLSLSSSTPP----LPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP---PPPVSR 387

Query: 163 ENEQKQAFPKLTGVKGKFMSASQDLEPKPLFP--KPAFGQKPP----LSTENSHEDESPM 216
                +A P    +  +    S    P+P  P  +P+ G  PP     S  N  +D SP 
Sbjct: 388 NGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQD-SPC 446

Query: 217 KNVSSSK---------GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGV 262
           ++   S+           P P    +KS P K AR +S +  +  E  + P P +
Sbjct: 447 EDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPI 501



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 92/382 (24%), Positives = 128/382 (33%), Gaps = 80/382 (20%)

Query: 58  GSPKPPVAVKP--SSEEKPDKEPKPPFLKPTGA-GQRFGTPASLTTRDPEAKVGFLKPVG 114
           G  +PP+      S+  KP   P  P   P  + G R G P     R P  +      VG
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPR----PDVG 177

Query: 115 PKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKS---GPTPPTSENEQKQAFP 171
            KP ++P     P+ P P  + P     N+     P GP+    GPTPP         FP
Sbjct: 178 SKPDSIPPP--VPSTPRPIQSSPH----NRGSPPVPGGPRQPSPGPTPPP--------FP 223

Query: 172 KLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHE-DESPMKNVSSSKGSPAPLG 230
              G +G  +     +   PL     F  +PPL    S   D+ P          P P  
Sbjct: 224 ---GNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRALDDKP---------PPPPPP 270

Query: 231 VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLK-----PAASRGGPGLSKNGEEKKED 285
           V ++    + A      +++   + S P P    +     P  SR GP          ++
Sbjct: 271 VGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 286 RKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQK 345
                 +N          L+S TPP   P     L                     P ++
Sbjct: 331 TPRLPQRNL--------SLSSSTPPLPSPGRSGPLP------------------PPPSER 364

Query: 346 PLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPP 405
           P PP+    PP      PP   +++   TS     +    S S    P   P     +PP
Sbjct: 365 PPPPV--RDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGP-----RPP 417

Query: 406 LPASHPS----QPPVPSLPPRN 423
           LP   PS     PP PS   RN
Sbjct: 418 LPPDRPSAGAPPPPPPSTSIRN 439



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 61/258 (23%), Positives = 86/258 (33%), Gaps = 66/258 (25%)

Query: 224 GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG---VVLKPAASRGGPGL----- 275
           G P  LG   ++G  K     + + D  G    L  PG      KP +   GPG      
Sbjct: 95  GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154

Query: 276 --SKNGEEKKEDRKIDAAKNTFQSK--------------INQEELASGTPPARF-PKAPS 318
              ++G  + +  ++   +    SK              I       G+PP    P+ PS
Sbjct: 155 PGHRSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPS 214

Query: 319 KLTVGGPW---------GQSQEKEKGDKNSATPKQKPLPP-----LFTLGPPPPKP--NR 362
                 P+         G S  +     +S    + PLPP     L    PPPP P  NR
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR 274

Query: 363 PPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH---PASQPPLPASHPSQPPVPSL 419
           P                      S    ++PPPPP +   P    P P++    PP P  
Sbjct: 275 P----------------------SIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPP 312

Query: 420 PPRNIKPPFDLKSPVNED 437
           P R   PP    S  N++
Sbjct: 313 PSRPGPPPLPPSSSGNDE 330


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 127/489 (25%), Positives = 165/489 (33%), Gaps = 85/489 (17%)

Query: 24   TGPNSSSGIQARKNLFNNQGNASP---PAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKP 80
            +G +   G + ++ LF  +G+  P   P  P  V   G P PP     + +      P P
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253

Query: 81   PFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPW---PPGNKP 137
            P   P G     G P +   + P   +G    VG K    P E  +P  P    PPG K 
Sbjct: 1254 P--GPRGPS---GAPGADGPQGPPGGIGNPGAVGEK--GEPGEAGEPGLPGEGGPPGPKG 1306

Query: 138  SLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPA 197
                  +       GP  GP  P  ++  K + P   G  G       D  P P  P PA
Sbjct: 1307 ERGEKGESGPSGAAGPP-GPKGPPGDDGPKGS-PGPVGFPG-------DPGP-PGEPGPA 1356

Query: 198  FGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSEN--KDHAGEIS 255
                PP   +   + E          G P P G   K GP  PA  +     K   GE +
Sbjct: 1357 GQDGPP--GDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE-A 1413

Query: 256  SLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPK 315
             L  P     P   +G PG  K G +                 + ++ L  G+P    P 
Sbjct: 1414 GLEGPPGKTGPIGPQGAPG--KPGPD---------GLRGIPGPVGEQGLP-GSPGPDGPP 1461

Query: 316  APSKLTVGGPWGQSQEKEKGDKNSATPK-QKPLPPLFTLGPPPPKPNRPPNVDLTKFHKT 374
             P      GP G       G K  + PK +K  P L  L  PP +     +  L    + 
Sbjct: 1462 GPM-----GPPGLP-----GLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPG-PQG 1510

Query: 375  SSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLP---------------ASHPSQPPVPSL 419
            SSG    +G T  S    PP PP  P   PP P               A HP  PP P  
Sbjct: 1511 SSGPKGEQGITGPSGPIGPPGPPGLPG--PPGPKGAKGSSGPTGPKGEAGHPG-PPGPPG 1567

Query: 420  PPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKE------REK 473
            PP  +  P  +++     N D     D         D  GE Y D     E         
Sbjct: 1568 PPGEVIQPLPIQASRTRRNIDASQLLD---------DGNGENYVDYADGMEEIFGSLNSL 1618

Query: 474  KREKEEKKR 482
            K E E+ KR
Sbjct: 1619 KLEIEQMKR 1627



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 109/415 (26%), Positives = 139/415 (33%), Gaps = 79/415 (19%)

Query: 25   GPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLK 84
            GP    G    + L   +G   PP  P      G P P   V P        EP PP   
Sbjct: 670  GPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG------EPGPP--- 720

Query: 85   PTGAGQRFGTPASLTTRDPEAKVGFLKPVGPK-PINLPKEDSKPTFPWPPGNKPSLHSVN 143
                GQ+ G P +     P+  +G   P G K P+  P     P    PPG+ P      
Sbjct: 721  ----GQQ-GNPGAQGLPGPQGAIG---PPGEKGPLGKPGLPGMPGADGPPGH-PGKEG-- 769

Query: 144  QDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPP 203
                  P G K G  PP  +      +P   GVKG      + L       K   G+K  
Sbjct: 770  ------PPGEKGGQGPPGPQG--PIGYPGPRGVKG--ADGIRGL-------KGTKGEK-- 810

Query: 204  LSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHA-----GEISSLP 258
               E+          +   +G   P G R + GP  P      N D       GE   L 
Sbjct: 811  --GEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLG 868

Query: 259  FPGVV-----LKPAASRGGPGL-SKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPAR 312
             PG+        P  S G PG    NGE+          + T   K         T P R
Sbjct: 869  VPGLPGYPGRQGPKGSIGFPGFPGANGEK--------GGRGT-PGKPGPRGQRGPTGP-R 918

Query: 313  FPKAPSKLT-VGGPWGQSQEKEKGDKNSATPKQK-PLPPLFTLGPPPPK-PNRPPNVDLT 369
              + P  +T   GP G S     GD  +  P ++ P  P    G P PK P  PP  D  
Sbjct: 919  GERGPRGITGKPGPKGNS----GGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD-- 972

Query: 370  KFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQP---PVPSLPP 421
                   G+   +G+T +   + PP PP     Q P   + P      P P  PP
Sbjct: 973  ----GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 111/483 (22%), Positives = 142/483 (29%), Gaps = 78/483 (16%)

Query: 25   GPNSSSGIQARKNLFNNQGNASPPA-----GPSNVPKFGSPKPPVAVKPSSEEKPDKEPK 79
            GP   +G    K      G A PP      GP     F  PK P    P    K      
Sbjct: 922  GPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGP----PGPPGKDGLPGH 977

Query: 80   PPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVG----PKPINLPKEDSKPTFPWPPGN 135
            P     TG   + G P       P+   G   P+G    P P   P E   P      G 
Sbjct: 978  PGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT 1037

Query: 136  K--------------PSLHSVNQDHDLK-PLG---------PKSGPTPPTSENEQKQAFP 171
            K              P L     D  L  P+G         P   P P  S  E+  A  
Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097

Query: 172  K-LTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG 230
                G+ G+         P P   K A G+K P             +  +   G   P+G
Sbjct: 1098 AGPIGIPGR---PGPQGPPGPAGEKGAPGEKGP-------------QGPAGRDGLQGPVG 1141

Query: 231  VRSKSGPLKPAREDSE--------NKDHAGEISSLPFPGVVLKPAASRGGPGLS-KNGEE 281
            +   +GP+ P  ED +         K   G+      PG    P    G PG S  +GE 
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPT-GPQGPIGQPGPSGADGEP 1200

Query: 282  KKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEK-EKGDKNSA 340
                +     +  F  K ++        P  FP  P  + + G  G   EK E GD    
Sbjct: 1201 GPRGQ-----QGLFGQKGDE-------GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248

Query: 341  TPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
             P   P P   +  P    P  PP            G     G+        PP P    
Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGER 1308

Query: 401  ASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGE 460
              +     S  + PP P  PP +   P     PV      G     G    D     +G+
Sbjct: 1309 GEKGESGPSGAAGPPGPKGPPGD-DGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367

Query: 461  TYE 463
              E
Sbjct: 1368 DGE 1370



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 106/493 (21%), Positives = 165/493 (33%), Gaps = 71/493 (14%)

Query: 9   NPTEDVSVNS---RPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVA 65
           +P +D++       P + T P + + I       +N  N +PP G       G+      
Sbjct: 350 SPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGE------GADDLEGE 403

Query: 66  VKPSSEEKPDKEPKPPFLKPTGAGQRFGT--PASLTT--------RDPEAKVGFLKPVGP 115
               +    D+    P+  PT +    G   PA+  T        R  + + G    + P
Sbjct: 404 FTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEP 463

Query: 116 KPI--NLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKL 173
             +    P  +     P PPG   ++    Q  D    GP   P  P ++         L
Sbjct: 464 GMLIEGPPGPEGPAGLPGPPG---TMGPTGQVGDPGERGPPGRPGLPGADG--------L 512

Query: 174 TGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPA-PLGVR 232
            G  G  +     + P         G K P+ +    + ++ ++    +   PA P+G+ 
Sbjct: 513 PGPPGTML-----MLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLT 567

Query: 233 SKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAK 292
            + GP+ P       K   G++     P  V  P    G PG  + G    +  +    +
Sbjct: 568 GRPGPVGPPGSGG-LKGEPGDVGP-QGPRGVQGPPGPAGKPG--RRGRAGSDGARGMPGQ 623

Query: 293 NTFQSKINQEELAS--GTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKP--LP 348
              +     + LA   G    R    PS    G P     + E+GD     P+  P    
Sbjct: 624 TGPKGDRGFDGLAGLPGEKGHRGDPGPS----GPPGPPGDDGERGDDGEVGPRGLPGEPG 679

Query: 349 PLFTLGPP-PPKPNRPPNVDLTKFHKTSSGNSTSKG-------QTSYSTTSLP------- 393
           P   LGP  PP P  PP V          GN   +G       Q +     LP       
Sbjct: 680 PRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG 739

Query: 394 PPPPSHPASQPPLP----ASHPSQPPVPSLPP--RNIKPPFDLKSPVNEDNQDGVTHSDG 447
           PP    P  +P LP    A  P   P    PP  +  + P   + P+      GV  +DG
Sbjct: 740 PPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADG 799

Query: 448 AGNLDEEQDSEGE 460
              L   +  +GE
Sbjct: 800 IRGLKGTKGEKGE 812



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 115/468 (24%), Positives = 145/468 (30%), Gaps = 79/468 (16%)

Query: 17   NSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDK 76
            N  P    GP    G    + L   QG   PP     + K G P  P A  P     P K
Sbjct: 710  NVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH--PGK 767

Query: 77   EPKPPFLK----PTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWP 132
            E  PP  K    P G     G P     +  +   G     G K      ED  P F   
Sbjct: 768  E-GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEK-----GEDGFPGFKGD 821

Query: 133  PGNKPSLHSVNQD---HDLKPLGPKS--------GPTPPTSENEQKQAFPKLTGVKGK-- 179
             G K     +       +  P GPK         GP  P  E + K   P L G  G+  
Sbjct: 822  MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE-KGKLGVPGLPGYPGRQG 880

Query: 180  ---------FMSASQDLEPKPLFPKPA-FGQKPPLSTENSHEDESPMKNVSSSKGSPAPL 229
                     F  A+ +   +    KP   GQ+ P             +      G P P 
Sbjct: 881  PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGE-------RGPRGITGKPGPK 933

Query: 230  GVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKID 289
            G     GP  P  E   N    G      FPG    P    G PG  K+G      ++  
Sbjct: 934  GNSGGDGPAGPPGERGPN----GPQGPTGFPG----PKGPPGPPG--KDGLPGHPGQR-- 981

Query: 290  AAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKN-SATPKQKPLP 348
              +  FQ K        G P    P+ P+  T  GP G     E+G       P ++ LP
Sbjct: 982  -GETGFQGKTG----PPGPPGVVGPQGPTGET--GPMG-----ERGHPGPPGPPGEQGLP 1029

Query: 349  PLF----TLGPPPPK----PNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
             L     T G P P      + PP +      +   G   + G         PP P   P
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089

Query: 401  ASQPPLPASHPSQPPVPSLP-PRNIKPPFDLKSPVNEDNQDGVTHSDG 447
              + P  A+ P    +P  P P+    P   K    E    G    DG
Sbjct: 1090 GERGPAGAAGPI--GIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 110/426 (25%), Positives = 150/426 (35%), Gaps = 58/426 (13%)

Query: 26  PNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKP 85
           P + S   AR++         P   PS  P+  +  P  +V  +SE     EP P   + 
Sbjct: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT-EPSPAARRR 218

Query: 86  TGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQD 145
             AG     PAS +       +      GP     P+  + P+ P P G           
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG----------- 267

Query: 146 HDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLS 205
             L+ L P    TPP     +K A P L       +S+S    P P  P P+    P L 
Sbjct: 268 --LQALRPPQ-VTPP-----RKDAAPALGP-----LSSSPLATPSPSAP-PSPSAPPSLQ 313

Query: 206 TENSHEDESPMKNVSSSKGSPAPLGVRS--KSGPLKPAREDSENKDHAGEISSLPFPGVV 263
           T  S    +P    ++S GSP      S   S PL P          A  +  L  P   
Sbjct: 314 TLPS-PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP-- 370

Query: 264 LKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKL--- 320
             P AS     L+    +      +   +  F    +    A  +PPA  P +PS     
Sbjct: 371 -SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429

Query: 321 ----TVGGPWGQ---SQEKEKGDKNSATPKQKPLPPLFTLGPP----PPKPNRPPNVDLT 369
               ++  P  Q   S         SATP  +  PPL    PP     P P  PP +   
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQLAKPPPQAPPALATP 487

Query: 370 KFHKTSSGNSTSKGQTSYS-TTSLP------PPPPSHPASQPPLPASHPSQPPVPSL-PP 421
                 S  ++  GQ  +S + SLP      PPP + P    PL    PS P  P+L  P
Sbjct: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547

Query: 422 RNIKPP 427
           R  +PP
Sbjct: 548 R--RPP 551



 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 104/440 (23%), Positives = 152/440 (34%), Gaps = 103/440 (23%)

Query: 8   GNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVK 67
           G+P     V     RV G   ++G   RK L    G       P + P+ G         
Sbjct: 31  GSPRPPPPVTPAALRVLG---AAGAVGRKPLAERAGGIGGATIPESAPRAG--------- 78

Query: 68  PSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLK------PVGPKPINLP 121
                 P +  +PP    +G G+R   PA  T+  P +  G         P+G K + + 
Sbjct: 79  ------PTRTSRPP---ASGRGER-APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128

Query: 122 KEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFM 181
            E++          K S  S     D       SGPTP T       A  + +   G  +
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDT------SGPTPGTPS----PAMARRSRAAGTEV 178

Query: 182 SASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPA 241
              +        P P+   +PP         E P K+VSS+                   
Sbjct: 179 GLPR--------PAPSARPRPPT--------EGPRKSVSSAS------------------ 204

Query: 242 REDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQ 301
                  +H+   ++ P P    +P+A  GG      G ++   R + ++     S    
Sbjct: 205 -------EHS---TTEPSPAARRRPSA--GG------GLQRPASRSLSSSATPLSSPARS 246

Query: 302 EELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLP--PLFTLGPP-PP 358
              A GTP  R P  PS+    G       +    +  A P   PL   PL T  P  PP
Sbjct: 247 GPSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304

Query: 359 KPNRPPNVDLTKFHKTS--SGNSTSKGQ-TSYSTTSLPPPPPSHPASQPPLPASHPSQPP 415
            P+ PP++        +  S  +TS G  T  +T S  P PP  P + PP     P  PP
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-----PQAPP 359

Query: 416 VPSLPPRNIKPPFDLKSPVN 435
             +LPP    P      P++
Sbjct: 360 ALALPPLQAPPSPPASPPLS 379



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 76/371 (20%), Positives = 114/371 (30%), Gaps = 68/371 (18%)

Query: 44  NASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDP 103
           +A+P  GP +     +P P     PS+       P PP   P+ A    G+P    T   
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS- 340

Query: 104 EAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSE 163
                FL      P+  P   + P    PP   P     +      PL P + P+P    
Sbjct: 341 -----FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-----PLSPLATPSPQAPN 390

Query: 164 NEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSK 223
                             + +  L   P  P P+    PP+    S    SP  + S++ 
Sbjct: 391 ------------------ALAVHLLQAPFSPPPS----PPVQAPFS-PPASPPVSPSATP 427

Query: 224 GSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKK 283
            S AP                           SL  P + + P+     P         +
Sbjct: 428 PSQAP--------------------------PSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 284 EDRKIDAAKNTFQSKINQEELASGTPPAR-FPKAPSKLTVGGPWGQSQEKEKGDKNSATP 342
               + A          Q   A  TPP +  P  P+      P+  S         +  P
Sbjct: 462 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521

Query: 343 KQKPL--PPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHP 400
           +  P+   PL  +   PP P   P +   +   T   +++  G     T +L P PP  P
Sbjct: 522 QAPPVLAAPLLQV---PPSPPASPTLQAPRRPPTPGPDTSVSGPR--LTLALAPGPPPPP 576

Query: 401 ASQPPLPASHP 411
           +  P    S P
Sbjct: 577 SRSPSSTLSGP 587


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 95/387 (24%), Positives = 139/387 (35%), Gaps = 76/387 (19%)

Query: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAG----QRFGTPASLTTRDPEAKVGFLKPVGPK 116
           KP   +KP  +++P K    P  K  G G    Q+ GTP S++++ PE K+    P   K
Sbjct: 202 KPEGIIKPPLQQQPPK----PIPKQQGPGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGK 256

Query: 117 PINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV 176
           PI  P +  +                  DH   PL  +    P T + +          V
Sbjct: 257 PIQGPTQTPQT-----------------DHAKLPL-QRDASRPQTKQADI---------V 289

Query: 177 KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG------ 230
           +G+ +  S     KP   +P  G+ P     +      P K  +   G   PL       
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349

Query: 231 ---------VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKN--- 278
                     +  + PL PA+  ++        S  P P  + +P      PG+ K    
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------PGVGKTPAQ 403

Query: 279 --GEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPW-GQSQEKEKG 335
             G  K   +++   K   Q    Q  L S   PA+ P  P+K  V  P  G+   ++ G
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQ----QPGLQS---PAKAP-GPTKTPVQQPGPGKIPAQQAG 455

Query: 336 D-KNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPP 394
             K SA       PP    GP  P P +P      K      G++    Q   ST   P 
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA---KPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 395 PP-PSHPASQPPLPASHPSQPPVPSLP 420
            P P+ P+ Q P     PSQ P  + P
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKP 539



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 115/493 (23%), Positives = 163/493 (33%), Gaps = 82/493 (16%)

Query: 18  SRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPK-----FGSPKPPVAVKPSSEE 72
           S+P     P   SG+   K L    G   PP  P    K      G  KPP A +  SE+
Sbjct: 324 SQPGPAKPPAQPSGLT--KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEK 380

Query: 73  KPDKEPKPPFL-KPTGAGQRFGTPASLT--TRDPEAKVGFLKPVGPKP-----INLPKED 124
              ++P P  L +P G G+   TPA      + P  +VG  KP+  +P        P   
Sbjct: 381 PSSEQPGPKALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 125 SKPTFPWPPGNKPSLH------SVNQDHDLKPLGPKSGPT-PPTSENEQKQAFPKLTGVK 177
             P     PG  P+        S  Q    KP     GP  PP  +    +  P+  G  
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497

Query: 178 GKFMSASQDLEPKPLFPKPAF-------GQKPPL----STENSHEDESPMKNVSSSKGSP 226
                     +P P  P PA          KPP     S + S +  SP K   S++ S 
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK--PSAQQST 555

Query: 227 APLGVRSKSGPLKPAREDSENKD---------------------HAGEISSLPFPGVVLK 265
            P+       PL+P       K                      H  E ++         
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615

Query: 266 PAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELAS--GTPPARFPKAPSKLTVG 323
              S  G   + +  E KE   +    N    +    +LA    +P  +   AP   T  
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 324 GPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKG 383
                 Q ++   K  A PKQ       +  P P KP  PP V     H + S  +    
Sbjct: 672 VSKSSPQPQQTSPKKDAAPKQD-----LSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPP 724

Query: 384 QTSYSTTSLPPPPPSHPASQPPLPAS--HPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDG 441
           +    +   PP  PS P+ Q   P +   P Q       P+ +KP  DL S  +   +  
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ-------PKMVKPTTDLVSSSSATTKPD 777

Query: 442 VTHSDGAGNLDEE 454
           +  S      +E+
Sbjct: 778 IPSSKVQSQAEEK 790



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 100/451 (22%), Positives = 156/451 (34%), Gaps = 79/451 (17%)

Query: 55   PKFGSPKPPVAVKPSSEEKPDKEPKPPFLK-PTGAGQRFGTPASLTTRDPEAKVGFLKPV 113
            P+  SPK   A K    + P+ +  PP +K PT      G+P++   + PEA     KP 
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT----LHGSPSAKAKQPPEAD-SLSKPA 733

Query: 114  GPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKL 173
             PK  ++P E  K                    D KP  PK    P T       A  K 
Sbjct: 734  PPKEPSVPSEQDKAPVA----------------DDKPKQPKM-VKPTTDLVSSSSATTKP 776

Query: 174  TGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRS 233
                 K  S +++    PL    A   KP  S   + E  SP      SK  P P     
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSA---KPSQSFPPTGEKVSPF----DSKAIPRP----- 824

Query: 234  KSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKN 293
                      DS+   H G             P++   G       ++K+E +K   A+ 
Sbjct: 825  --------ASDSKIISHPG-------------PSSESKGQKQVDPVQKKEEPKK---AQT 860

Query: 294  TFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL 353
                K + + +  G+P    P+  +  TV  P    + +E+  + S          L ++
Sbjct: 861  KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN--------LGSI 912

Query: 354  GPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ 413
               P      P   +T        +  S+     ST   P P        P   A  PSQ
Sbjct: 913  TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972

Query: 414  PPVPSLPPRNI--KPPFDLKS-PVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKE 470
            PP    PP++    PP   KS PV ++ +             E+ + + E    ++ ++ 
Sbjct: 973  PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA---------EKLEPKAEQAPTVKRTET 1023

Query: 471  REKKREKEEKKRLELEKKEQKEKEKKEQEIK 501
             +K    ++ K L  E ++     K E+  K
Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK 1054



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 163/749 (21%), Positives = 264/749 (35%), Gaps = 125/749 (16%)

Query: 47   PPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAK 106
            PP G   V  F S   P   +P+S+ K    P P        GQ+   P        +A+
Sbjct: 807  PPTG-EKVSPFDSKAIP---RPASDSKIISHPGP---SSESKGQKQVDPVQKKEEPKKAQ 859

Query: 107  VGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQ 166
                  + PKP   P     PT   PPG +P+               ++ PTP  S   Q
Sbjct: 860  T----KMSPKPDAKPMPKGSPT---PPGPRPT-------------AGQTVPTPQQSPKPQ 899

Query: 167  KQAFPKLTGVKGKFMSA--SQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKG 224
            +Q+  + +   G    A  SQ   P+       FG    + ++ S        N+ S+ G
Sbjct: 900  EQS-RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS--------NLISTAG 950

Query: 225  SPAPLGVRSKSGPLKPAREDSENKDHAGE-----------ISSLPFPGVVLKPAASR--- 270
             P P        P+K A   S+     G              S+P       PAA +   
Sbjct: 951  QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010

Query: 271  ---GGPGLSKNGEEKKEDRKIDAAKNTFQSK---INQEELASGTPPARFPKAPSKLTVGG 324
                 P + +   EKK     D+   T + +   +  +   S  P +  P   ++L +G 
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070

Query: 325  PWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQ 384
                   K+  + N+ T  +  +  L    P P          LT+  +    N  ++  
Sbjct: 1071 -------KDPPNFNTCTECKNQVCNLCGFNPTP---------HLTEIQEWLCLNCQTQRA 1114

Query: 385  TSYSTTSLP--PPPPSHPASQP-PLPASHPSQ-----PPVPSLPPRNIKPPFDLKSPVNE 436
             S     +   PP PS P + P P+P    SQ     P V  +  +  +   + +  + E
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174

Query: 437  DNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKK 496
              ++ ++       +  +Q  E    E  +AS  +EKK   EEKK +  E+K + E++K 
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234

Query: 497  EQEIKK----------KFKLTGPIQVIH-LAKACCDVKGGKNE-----LSFKQGEQIEII 540
              E KK          + K + P +  H L K+   +   K E      + ++G+Q    
Sbjct: 1235 LLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ---- 1290

Query: 541  RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600
                 P+ K  G  +       K      D  + K  K+    P     D  E   +  E
Sbjct: 1291 -----PQTKMEGLPSGTPQSLPKE-----DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340

Query: 601  QDDISSHSQSGSGGIFPPPPDDDIY--DGIEEEDADDGSTLQVQEKSNTWSWGILKMLKG 658
            ++D  S + S      P    D  Y  DGI     +  S +   EK       ILK LK 
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD------ILKGLKK 1394

Query: 659  KDDRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAE-MSQGTN 717
                ++S    P  SD    E +       Q     +   +  T    VS  +   Q   
Sbjct: 1395 DSFSQESSPSSP--SDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKT 1452

Query: 718  VGKAKTEEKDL--KKLKKQEKEEKDFRKK 744
               ++T E  +  +++K+ ++E KD  KK
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKK 1481



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 106/461 (22%), Positives = 151/461 (32%), Gaps = 71/461 (15%)

Query: 10  PTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQ--GNASPPA---GPSNVP--KFGSPKP 62
           P +       P +  GP  +S  Q       +Q  G A PP    GP+  P  + GS KP
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499

Query: 63  PVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPK 122
           P + +P S + P ++P P    P   G         +T+ P  + G  KP   +P     
Sbjct: 500 P-SQQPGSTKPPPQQPGPAKPSPQQPG---------STKPPSQQPGSAKPSAQQPSPAKP 549

Query: 123 EDSKPTFP----------WPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAF-- 170
              + T P           PP   PS          K + P    T       +K  F  
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609

Query: 171 -----------------PKLTGVKGKFMSASQ-------DLEPKPLFPKPAFGQKPPLST 206
                            P LT VK       Q       DL P P  P+P   +  P++T
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL-KTAPVTT 668

Query: 207 ENSHEDESPMKNVSSSKGSPAPLGVRSKS-GPLKP---AREDSENKDHAGEISSLPFPGV 262
            ++    SP    +S K   AP    SK+  P KP    ++ + +   + +    P    
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728

Query: 263 VLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTV 322
           + KPA  +     S   E+ K     D  K     K   + ++S +   + P  PS    
Sbjct: 729 LSKPAPPKEP---SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK-PDIPSSKV- 783

Query: 323 GGPWGQSQEKEKGDKNSATPKQKP---LPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNS 379
                QSQ +EK      T   KP    PP      P      P     +K       +S
Sbjct: 784 -----QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838

Query: 380 TSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
            SKGQ           P        P P + P     P+ P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 153/733 (20%), Positives = 250/733 (34%), Gaps = 154/733 (21%)

Query: 8    GNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVK 67
            G P +     S+P    GP  S+G              +PPA   ++P     K P A K
Sbjct: 961  GAPMKQAPAPSQPPTSQGPPKSTG-------------QAPPAPAKSIPVKKETKAPAAEK 1007

Query: 68   --PSSEEKP-----DKEPKPPFLKPTGAGQRFGTPASLTTR-DPEAKVGFLKPVGPKPIN 119
              P +E+ P     + E KPP +K + +       A L T+ +   K     P+    +N
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067

Query: 120  LPKEDSKPTFPWPP----------GNKPSLHSVN-----------------QDHDLK--- 149
            +  +D  P F              G  P+ H                    Q  D++   
Sbjct: 1068 IGSKDP-PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 150  --PLGPKSGPTP-PTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKP----AFGQKP 202
              P GPK+ P P PT  + QK A P    +  K     +    K +  K     +  + P
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 203  PLSTENSHEDESPM-KNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG 261
            P+ T +  ++ES + K+ +S+     PL    K  P +      E K    E    P   
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK 1246

Query: 262  VVLKPAASRGGPGLSKN---------GEEKKEDRKID-AAKNTFQSKINQEELASGTPPA 311
             +L P A    P   K+          EEK E R      +   Q +   E L SGTP +
Sbjct: 1247 KLL-PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQS 1305

Query: 312  RFPKAPSKLTVG----------------GPWGQSQEKEKGDKNSATPKQKPLPPL----- 350
              PK   K T                   P  +  EKE  DK+  +  Q+P  P      
Sbjct: 1306 -LPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED-DKSDTSSSQQPKSPQGLSDT 1363

Query: 351  ---------------------------------FTLGPPPPKPNRPPNVDLTKFHKTSSG 377
                                             F+    P  P+    ++ T      + 
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQ 1423

Query: 378  NSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFD-LKSPVNE 436
             ST   + S   T      P  P  Q    +   S+    ++    IK   +  K    +
Sbjct: 1424 ASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL--SETLEITISEEEIKESQEERKDTFKK 1481

Query: 437  DNQDGVTHSDGAGNLDEEQD---SEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEK 493
            D+Q  +  S       E  D   +  E Y+ +E S E E     + K+R  +      E 
Sbjct: 1482 DSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541

Query: 494  EKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDN---PEGKW 550
            ++++ +   + +     Q+I ++ A  D  G +++  F + +  EI   T++    E K 
Sbjct: 1542 KQEDSQGSGEEEDFIRKQIIEMS-ADEDASGSEDD-EFIRNQLKEISSSTESQKKEETKG 1599

Query: 551  LGRTARGSYGYI-KTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQ 609
             G+   G +  + + ++  ID D+        G      ++D E +D+  E     + SQ
Sbjct: 1600 KGKITAGKHRRLTRKSSTSIDEDA--------GRRHSWHDEDDEAFDESPELKYRETKSQ 1651

Query: 610  -------SGSGGI 615
                   +G GG+
Sbjct: 1652 ESEELVVTGGGGL 1664



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 170/815 (20%), Positives = 291/815 (35%), Gaps = 191/815 (23%)

Query: 47   PPAGPSNVPKFGS---------PKPPVAVKPSSEEK-PDKEPKPPFLKPTGAGQRFGTPA 96
            P   P ++PK            P+PP   KP   E   +K  K      T + Q+  +P 
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358

Query: 97   SLTTRDPEAKVGFLKPVGPKPINLPKED------------SKPTFPWPPGNKPSLHSV-- 142
             L+     +  G    +G  P  +P ++            S+ + P  P +   L S   
Sbjct: 1359 GLSDTGYSSD-GISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417

Query: 143  ------------------NQDHDLKPLGPKSGPTPPT----------------SENEQKQ 168
                               Q H++ P  PK      +                S+ E+K 
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKD 1477

Query: 169  AFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPL-STENSHEDES---PMKNVSSSKG 224
             F K +    + + +S+D + K  F      ++ P  S E S E E+   P +   +S G
Sbjct: 1478 TFKKDSQ---QDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVG 1534

Query: 225  SPAPLGVRSKSGPLKPARED---------SENKDHAGEISSLPFPGVVLKPAASRGGPGL 275
            S +    + +        ED         S ++D +G      F    LK  +S      
Sbjct: 1535 SSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDD-EFIRNQLKEISSSTE--- 1590

Query: 276  SKNGEEKKEDRKIDAAKN---TFQSKINQEELASG--------------TPPARFPKAPS 318
            S+  EE K   KI A K+   T +S  + +E A                +P  ++ +  S
Sbjct: 1591 SQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKS 1650

Query: 319  K----LTVGGPWGQSQEKEK------GDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDL 368
            +    L V G  G  + K         DK SA   QK     F         +  P +++
Sbjct: 1651 QESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYF---------DEEPELEM 1701

Query: 369  TKFHKTSSGNSTSKGQTSYSTTSLPP-PPPSHPASQPPLPASHPSQPPVPSLPPRNIKP- 426
                 +    S  +G +S   +S  P   P+  +S      S PS     S   R  +  
Sbjct: 1702 ESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR 1761

Query: 427  PFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELE 486
            P     P  ED+ +                 E E  E+ E  KE+EK+RE E+++R    
Sbjct: 1762 PHGPLLPTIEDSSE-----------------EEELREEEELLKEQEKQREIEQQQRKSSS 1804

Query: 487  KKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIR----- 541
            KK +K+K++   + +++   T P  +  +  A         E   +  E  E+ R     
Sbjct: 1805 KKSKKDKDELRAQRRRERPKTPPSNLSPIEDA------SPTEELRQAAEMEELHRSSCSE 1858

Query: 542  ----ITDNPEGKWLG--RTARGSYGYIKTTAVEI----DYDSLKLKKDSLGAPSRPIEDD 591
                I  +PEG  +   +       Y   TAV +    D  S+  K+ S     + ++  
Sbjct: 1859 YSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGS----QKALKSA 1914

Query: 592  QEVYDDVA-------------EQDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDAD---D 635
            +E+Y+++              E+D++        G +     +D IY+ + E+  +   D
Sbjct: 1915 EEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLI----EDYIYESLVEDTYNGSVD 1970

Query: 636  GSTLQVQEKSNTWSWGILKMLKGKDDRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDE 695
            GS L  QE+ N    G ++  KG   R++ IR   ++ +    + +       +L+    
Sbjct: 1971 GSLLTRQEEEN----GFMQQ-KG---REQKIRLSEQIYEDPMQKITDLQKEFYELESLHS 2022

Query: 696  V--YDDVDTSDF--PVSSAEMSQGTNVGKAKTEEK 726
            V   +D+ +S F  P S   +  GT V   + E K
Sbjct: 2023 VVPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERK 2057



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 53/260 (20%), Positives = 82/260 (31%), Gaps = 48/260 (18%)

Query: 194  PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGE 253
            PKP       +ST+    ++ P+K      G+   L V       K    +      +  
Sbjct: 2279 PKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSET 2338

Query: 254  ISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPP-AR 312
            +   P   V+  P   +       +GE             TF  +    +L SG+P  + 
Sbjct: 2339 VFDHPPSSVIALPMKEQLSTTYFTSGE-------------TFGQEKPASQLPSGSPSVSS 2385

Query: 313  FPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVD----- 367
             P  P       P+ +S   +   +    P   P PP     PPPP P  PP        
Sbjct: 2386 LPAKPR------PFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPPPLPPPTSPKPTI 2437

Query: 368  ---------------------LTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPL 406
                                 +T    T+   S     T   TT+ PP PP   +    L
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGL 2497

Query: 407  PASHPSQPPVPSLPPRNIKP 426
              +H  +P  P + P+ + P
Sbjct: 2498 VFTHRPEPSKPPIAPKPVIP 2517



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 47/178 (26%), Positives = 63/178 (35%), Gaps = 36/178 (20%)

Query: 264  LKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSK---- 319
            +K A    G G+     E   D+K   A+ T   K +  E     PP+     P K    
Sbjct: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERT---KSSLSETVFDHPPSSVIALPMKEQLS 2357

Query: 320  ---LTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSS 376
                T G  +GQ  EK      S +P    LP         P+P          F ++SS
Sbjct: 2358 TTYFTSGETFGQ--EKPASQLPSGSPSVSSLPA-------KPRP----------FFRSSS 2398

Query: 377  GNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPV 434
             + +++          PPPPP  P   PP P   P  PP    P    K    + SPV
Sbjct: 2399 LDISAQPPP-------PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 39/179 (21%), Positives = 61/179 (34%), Gaps = 25/179 (13%)

Query: 265 KPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTP---PARFPKAP-SKL 320
           KP   + GPG     +  ++D    +  +    KI  +   +G P   P + P+   +KL
Sbjct: 217 KPIPKQQGPGR----DPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKL 272

Query: 321 TVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNST 380
            +           + D +    KQ  +    ++ P  P P++PP    T     +     
Sbjct: 273 PL-----------QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 381 SKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQ 439
            K Q        P  PP+ P+      A  P     P  PP   KPP     P     Q
Sbjct: 322 EKSQPG------PAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 53/227 (23%), Positives = 76/227 (33%), Gaps = 47/227 (20%)

Query: 48   PAGPSNVP-------KFGSPKPPVAVKPSSEEKPDKEPKPPFL--KPTGAGQRFGTPASL 98
            P  PS++P       +    KPP+A KP   + P    KP  +  KPTG         +L
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL 2546

Query: 99   TTRDPEAKVGFLKPVGPKP-----------------INLPKEDSKPT--------FPWPP 133
             T           P+ P                   I LP E   PT          WP 
Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606

Query: 134  GNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLF 193
            G+ PS        DL  + P     PP +  E   +  +   + G    A Q     P+ 
Sbjct: 2607 GS-PS-------KDLVSVEPVFSVVPPVTAVEIPISSEQTFYISG----ALQTFSATPVT 2654

Query: 194  PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240
               +F Q  P S       E     VS+++ +   +G+ S S  + P
Sbjct: 2655 APSSF-QAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 44/163 (26%), Positives = 58/163 (35%), Gaps = 14/163 (8%)

Query: 24   TGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFL 83
            +G  S S + A+   F    +    A P   P    P PP    P     P   P P   
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP----PPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 84   KPTGAGQRFGTPAS-LTTRDP--EAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSL- 139
            KPT   ++  T AS +TT  P  +A          +   LP      T P P   KPS  
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493

Query: 140  -HSVNQDHDLKPLGPKSGPTP-----PTSENEQKQAFPKLTGV 176
               +   H  +P  P   P P     PT+  +     PK TG+
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 95/387 (24%), Positives = 139/387 (35%), Gaps = 76/387 (19%)

Query: 61  KPPVAVKPSSEEKPDKEPKPPFLKPTGAG----QRFGTPASLTTRDPEAKVGFLKPVGPK 116
           KP   +KP  +++P K    P  K  G G    Q+ GTP S++++ PE K+    P   K
Sbjct: 202 KPEGIIKPPLQQQPPK----PIPKQQGPGRDPLQQDGTPKSISSQQPE-KIKSQPPGTGK 256

Query: 117 PINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV 176
           PI  P +  +                  DH   PL  +    P T + +          V
Sbjct: 257 PIQGPTQTPQT-----------------DHAKLPL-QRDASRPQTKQADI---------V 289

Query: 177 KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG------ 230
           +G+ +  S     KP   +P  G+ P     +      P K  +   G   PL       
Sbjct: 290 RGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349

Query: 231 ---------VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKN--- 278
                     +  + PL PA+  ++        S  P P  + +P      PG+ K    
Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP------PGVGKTPAQ 403

Query: 279 --GEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPW-GQSQEKEKG 335
             G  K   +++   K   Q    Q  L S   PA+ P  P+K  V  P  G+   ++ G
Sbjct: 404 QPGPAKPPTQQVGTPKPLAQ----QPGLQS---PAKAP-GPTKTPVQQPGPGKIPAQQAG 455

Query: 336 D-KNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPP 394
             K SA       PP    GP  P P +P      K      G++    Q   ST   P 
Sbjct: 456 PGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA---KPPPQQPGSAKPPSQQPGSTKPPPQ 512

Query: 395 PP-PSHPASQPPLPASHPSQPPVPSLP 420
            P P+ P+ Q P     PSQ P  + P
Sbjct: 513 QPGPAKPSPQQPGSTKPPSQQPGSAKP 539



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 115/493 (23%), Positives = 163/493 (33%), Gaps = 82/493 (16%)

Query: 18  SRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPK-----FGSPKPPVAVKPSSEE 72
           S+P     P   SG+   K L    G   PP  P    K      G  KPP A +  SE+
Sbjct: 324 SQPGPAKPPAQPSGLT--KPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEK 380

Query: 73  KPDKEPKPPFL-KPTGAGQRFGTPASLT--TRDPEAKVGFLKPVGPKP-----INLPKED 124
              ++P P  L +P G G+   TPA      + P  +VG  KP+  +P        P   
Sbjct: 381 PSSEQPGPKALAQPPGVGK---TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 125 SKPTFPWPPGNKPSLH------SVNQDHDLKPLGPKSGPT-PPTSENEQKQAFPKLTGVK 177
             P     PG  P+        S  Q    KP     GP  PP  +    +  P+  G  
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497

Query: 178 GKFMSASQDLEPKPLFPKPAF-------GQKPPL----STENSHEDESPMKNVSSSKGSP 226
                     +P P  P PA          KPP     S + S +  SP K   S++ S 
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK--PSAQQST 555

Query: 227 APLGVRSKSGPLKPAREDSENKD---------------------HAGEISSLPFPGVVLK 265
            P+       PL+P       K                      H  E ++         
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615

Query: 266 PAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELAS--GTPPARFPKAPSKLTVG 323
              S  G   + +  E KE   +    N    +    +LA    +P  +   AP   T  
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCL----NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 324 GPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKG 383
                 Q ++   K  A PKQ       +  P P KP  PP V     H + S  +    
Sbjct: 672 VSKSSPQPQQTSPKKDAAPKQD-----LSKAPEPKKP--PPLVKQPTLHGSPSAKAKQPP 724

Query: 384 QTSYSTTSLPPPPPSHPASQPPLPAS--HPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDG 441
           +    +   PP  PS P+ Q   P +   P Q       P+ +KP  DL S  +   +  
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ-------PKMVKPTTDLVSSSSATTKPD 777

Query: 442 VTHSDGAGNLDEE 454
           +  S      +E+
Sbjct: 778 IPSSKVQSQAEEK 790



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 100/451 (22%), Positives = 156/451 (34%), Gaps = 79/451 (17%)

Query: 55   PKFGSPKPPVAVKPSSEEKPDKEPKPPFLK-PTGAGQRFGTPASLTTRDPEAKVGFLKPV 113
            P+  SPK   A K    + P+ +  PP +K PT      G+P++   + PEA     KP 
Sbjct: 679  PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT----LHGSPSAKAKQPPEAD-SLSKPA 733

Query: 114  GPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKL 173
             PK  ++P E  K                    D KP  PK    P T       A  K 
Sbjct: 734  PPKEPSVPSEQDKAPVA----------------DDKPKQPKM-VKPTTDLVSSSSATTKP 776

Query: 174  TGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRS 233
                 K  S +++    PL    A   KP  S   + E  SP      SK  P P     
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSA---KPSQSFPPTGEKVSPF----DSKAIPRP----- 824

Query: 234  KSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKN 293
                      DS+   H G             P++   G       ++K+E +K   A+ 
Sbjct: 825  --------ASDSKIISHPG-------------PSSESKGQKQVDPVQKKEEPKK---AQT 860

Query: 294  TFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL 353
                K + + +  G+P    P+  +  TV  P    + +E+  + S          L ++
Sbjct: 861  KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN--------LGSI 912

Query: 354  GPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQ 413
               P      P   +T        +  S+     ST   P P        P   A  PSQ
Sbjct: 913  TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972

Query: 414  PPVPSLPPRNI--KPPFDLKS-PVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKE 470
            PP    PP++    PP   KS PV ++ +             E+ + + E    ++ ++ 
Sbjct: 973  PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAA---------EKLEPKAEQAPTVKRTET 1023

Query: 471  REKKREKEEKKRLELEKKEQKEKEKKEQEIK 501
             +K    ++ K L  E ++     K E+  K
Sbjct: 1024 EKKPPPIKDSKSLTAEPQKAVLPTKLEKSPK 1054



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 163/749 (21%), Positives = 264/749 (35%), Gaps = 125/749 (16%)

Query: 47   PPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAK 106
            PP G   V  F S   P   +P+S+ K    P P        GQ+   P        +A+
Sbjct: 807  PPTG-EKVSPFDSKAIP---RPASDSKIISHPGP---SSESKGQKQVDPVQKKEEPKKAQ 859

Query: 107  VGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQ 166
                  + PKP   P     PT   PPG +P+               ++ PTP  S   Q
Sbjct: 860  T----KMSPKPDAKPMPKGSPT---PPGPRPT-------------AGQTVPTPQQSPKPQ 899

Query: 167  KQAFPKLTGVKGKFMSA--SQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKG 224
            +Q+  + +   G    A  SQ   P+       FG    + ++ S        N+ S+ G
Sbjct: 900  EQS-RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS--------NLISTAG 950

Query: 225  SPAPLGVRSKSGPLKPAREDSENKDHAGE-----------ISSLPFPGVVLKPAASR--- 270
             P P        P+K A   S+     G              S+P       PAA +   
Sbjct: 951  QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010

Query: 271  ---GGPGLSKNGEEKKEDRKIDAAKNTFQSK---INQEELASGTPPARFPKAPSKLTVGG 324
                 P + +   EKK     D+   T + +   +  +   S  P +  P   ++L +G 
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070

Query: 325  PWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQ 384
                   K+  + N+ T  +  +  L    P P          LT+  +    N  ++  
Sbjct: 1071 -------KDPPNFNTCTECKNQVCNLCGFNPTP---------HLTEIQEWLCLNCQTQRA 1114

Query: 385  TSYSTTSLP--PPPPSHPASQP-PLPASHPSQ-----PPVPSLPPRNIKPPFDLKSPVNE 436
             S     +   PP PS P + P P+P    SQ     P V  +  +  +   + +  + E
Sbjct: 1115 ISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILE 1174

Query: 437  DNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKK 496
              ++ ++       +  +Q  E    E  +AS  +EKK   EEKK +  E+K + E++K 
Sbjct: 1175 KVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKP 1234

Query: 497  EQEIKK----------KFKLTGPIQVIH-LAKACCDVKGGKNE-----LSFKQGEQIEII 540
              E KK          + K + P +  H L K+   +   K E      + ++G+Q    
Sbjct: 1235 LLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQ---- 1290

Query: 541  RITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAE 600
                 P+ K  G  +       K      D  + K  K+    P     D  E   +  E
Sbjct: 1291 -----PQTKMEGLPSGTPQSLPKE-----DDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340

Query: 601  QDDISSHSQSGSGGIFPPPPDDDIY--DGIEEEDADDGSTLQVQEKSNTWSWGILKMLKG 658
            ++D  S + S      P    D  Y  DGI     +  S +   EK       ILK LK 
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKD------ILKGLKK 1394

Query: 659  KDDRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDEVYDDVDTSDFPVSSAE-MSQGTN 717
                ++S    P  SD    E +       Q     +   +  T    VS  +   Q   
Sbjct: 1395 DSFSQESSPSSP--SDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKT 1452

Query: 718  VGKAKTEEKDL--KKLKKQEKEEKDFRKK 744
               ++T E  +  +++K+ ++E KD  KK
Sbjct: 1453 QSLSETLEITISEEEIKESQEERKDTFKK 1481



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 106/461 (22%), Positives = 151/461 (32%), Gaps = 71/461 (15%)

Query: 10  PTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQ--GNASPPA---GPSNVP--KFGSPKP 62
           P +       P +  GP  +S  Q       +Q  G A PP    GP+  P  + GS KP
Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499

Query: 63  PVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPK 122
           P + +P S + P ++P P    P   G         +T+ P  + G  KP   +P     
Sbjct: 500 P-SQQPGSTKPPPQQPGPAKPSPQQPG---------STKPPSQQPGSAKPSAQQPSPAKP 549

Query: 123 EDSKPTFP----------WPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAF-- 170
              + T P           PP   PS          K + P    T       +K  F  
Sbjct: 550 SAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT 609

Query: 171 -----------------PKLTGVKGKFMSASQ-------DLEPKPLFPKPAFGQKPPLST 206
                            P LT VK       Q       DL P P  P+P   +  P++T
Sbjct: 610 CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL-KTAPVTT 668

Query: 207 ENSHEDESPMKNVSSSKGSPAPLGVRSKS-GPLKP---AREDSENKDHAGEISSLPFPGV 262
            ++    SP    +S K   AP    SK+  P KP    ++ + +   + +    P    
Sbjct: 669 TSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADS 728

Query: 263 VLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTV 322
           + KPA  +     S   E+ K     D  K     K   + ++S +   + P  PS    
Sbjct: 729 LSKPAPPKEP---SVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK-PDIPSSKV- 783

Query: 323 GGPWGQSQEKEKGDKNSATPKQKP---LPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNS 379
                QSQ +EK      T   KP    PP      P      P     +K       +S
Sbjct: 784 -----QSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838

Query: 380 TSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
            SKGQ           P        P P + P     P+ P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 153/733 (20%), Positives = 250/733 (34%), Gaps = 154/733 (21%)

Query: 8    GNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVK 67
            G P +     S+P    GP  S+G              +PPA   ++P     K P A K
Sbjct: 961  GAPMKQAPAPSQPPTSQGPPKSTG-------------QAPPAPAKSIPVKKETKAPAAEK 1007

Query: 68   --PSSEEKP-----DKEPKPPFLKPTGAGQRFGTPASLTTR-DPEAKVGFLKPVGPKPIN 119
              P +E+ P     + E KPP +K + +       A L T+ +   K     P+    +N
Sbjct: 1008 LEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELN 1067

Query: 120  LPKEDSKPTFPWPP----------GNKPSLHSVN-----------------QDHDLK--- 149
            +  +D  P F              G  P+ H                    Q  D++   
Sbjct: 1068 IGSKDP-PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 150  --PLGPKSGPTP-PTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKP----AFGQKP 202
              P GPK+ P P PT  + QK A P    +  K     +    K +  K     +  + P
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 203  PLSTENSHEDESPM-KNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG 261
            P+ T +  ++ES + K+ +S+     PL    K  P +      E K    E    P   
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK 1246

Query: 262  VVLKPAASRGGPGLSKN---------GEEKKEDRKID-AAKNTFQSKINQEELASGTPPA 311
             +L P A    P   K+          EEK E R      +   Q +   E L SGTP +
Sbjct: 1247 KLL-PEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQS 1305

Query: 312  RFPKAPSKLTVG----------------GPWGQSQEKEKGDKNSATPKQKPLPPL----- 350
              PK   K T                   P  +  EKE  DK+  +  Q+P  P      
Sbjct: 1306 -LPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKED-DKSDTSSSQQPKSPQGLSDT 1363

Query: 351  ---------------------------------FTLGPPPPKPNRPPNVDLTKFHKTSSG 377
                                             F+    P  P+    ++ T      + 
Sbjct: 1364 GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQ 1423

Query: 378  NSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFD-LKSPVNE 436
             ST   + S   T      P  P  Q    +   S+    ++    IK   +  K    +
Sbjct: 1424 ASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL--SETLEITISEEEIKESQEERKDTFKK 1481

Query: 437  DNQDGVTHSDGAGNLDEEQD---SEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEK 493
            D+Q  +  S       E  D   +  E Y+ +E S E E     + K+R  +      E 
Sbjct: 1482 DSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSSDEY 1541

Query: 494  EKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDN---PEGKW 550
            ++++ +   + +     Q+I ++ A  D  G +++  F + +  EI   T++    E K 
Sbjct: 1542 KQEDSQGSGEEEDFIRKQIIEMS-ADEDASGSEDD-EFIRNQLKEISSSTESQKKEETKG 1599

Query: 551  LGRTARGSYGYI-KTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQ 609
             G+   G +  + + ++  ID D+        G      ++D E +D+  E     + SQ
Sbjct: 1600 KGKITAGKHRRLTRKSSTSIDEDA--------GRRHSWHDEDDEAFDESPELKYRETKSQ 1651

Query: 610  -------SGSGGI 615
                   +G GG+
Sbjct: 1652 ESEELVVTGGGGL 1664



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 170/815 (20%), Positives = 291/815 (35%), Gaps = 191/815 (23%)

Query: 47   PPAGPSNVPKFGS---------PKPPVAVKPSSEEK-PDKEPKPPFLKPTGAGQRFGTPA 96
            P   P ++PK            P+PP   KP   E   +K  K      T + Q+  +P 
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358

Query: 97   SLTTRDPEAKVGFLKPVGPKPINLPKED------------SKPTFPWPPGNKPSLHSV-- 142
             L+     +  G    +G  P  +P ++            S+ + P  P +   L S   
Sbjct: 1359 GLSDTGYSSD-GISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVL 1417

Query: 143  ------------------NQDHDLKPLGPKSGPTPPT----------------SENEQKQ 168
                               Q H++ P  PK      +                S+ E+K 
Sbjct: 1418 SILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKD 1477

Query: 169  AFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPL-STENSHEDES---PMKNVSSSKG 224
             F K +    + + +S+D + K  F      ++ P  S E S E E+   P +   +S G
Sbjct: 1478 TFKKDSQ---QDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVG 1534

Query: 225  SPAPLGVRSKSGPLKPARED---------SENKDHAGEISSLPFPGVVLKPAASRGGPGL 275
            S +    + +        ED         S ++D +G      F    LK  +S      
Sbjct: 1535 SSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDD-EFIRNQLKEISSSTE--- 1590

Query: 276  SKNGEEKKEDRKIDAAKN---TFQSKINQEELASG--------------TPPARFPKAPS 318
            S+  EE K   KI A K+   T +S  + +E A                +P  ++ +  S
Sbjct: 1591 SQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKS 1650

Query: 319  K----LTVGGPWGQSQEKEK------GDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDL 368
            +    L V G  G  + K         DK SA   QK     F         +  P +++
Sbjct: 1651 QESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYF---------DEEPELEM 1701

Query: 369  TKFHKTSSGNSTSKGQTSYSTTSLPP-PPPSHPASQPPLPASHPSQPPVPSLPPRNIKP- 426
                 +    S  +G +S   +S  P   P+  +S      S PS     S   R  +  
Sbjct: 1702 ESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHR 1761

Query: 427  PFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELE 486
            P     P  ED+ +                 E E  E+ E  KE+EK+RE E+++R    
Sbjct: 1762 PHGPLLPTIEDSSE-----------------EEELREEEELLKEQEKQREIEQQQRKSSS 1804

Query: 487  KKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIR----- 541
            KK +K+K++   + +++   T P  +  +  A         E   +  E  E+ R     
Sbjct: 1805 KKSKKDKDELRAQRRRERPKTPPSNLSPIEDA------SPTEELRQAAEMEELHRSSCSE 1858

Query: 542  ----ITDNPEGKWLG--RTARGSYGYIKTTAVEI----DYDSLKLKKDSLGAPSRPIEDD 591
                I  +PEG  +   +       Y   TAV +    D  S+  K+ S     + ++  
Sbjct: 1859 YSPSIESDPEGFEISPEKIIEVQKVYKLPTAVSLYSPTDEQSIMQKEGS----QKALKSA 1914

Query: 592  QEVYDDVA-------------EQDDISSHSQSGSGGIFPPPPDDDIYDGIEEEDAD---D 635
            +E+Y+++              E+D++        G +     +D IY+ + E+  +   D
Sbjct: 1915 EEMYEEMMHKTHKYKAFPAANERDEVFEKEPLYGGMLI----EDYIYESLVEDTYNGSVD 1970

Query: 636  GSTLQVQEKSNTWSWGILKMLKGKDDRKKSIREKPKVSDSDNNEGSSFPAPPKQLDMGDE 695
            GS L  QE+ N    G ++  KG   R++ IR   ++ +    + +       +L+    
Sbjct: 1971 GSLLTRQEEEN----GFMQQ-KG---REQKIRLSEQIYEDPMQKITDLQKEFYELESLHS 2022

Query: 696  V--YDDVDTSDF--PVSSAEMSQGTNVGKAKTEEK 726
            V   +D+ +S F  P S   +  GT V   + E K
Sbjct: 2023 VVPQEDIVSSSFIIPESHEIVDLGTMVTSTEEERK 2057



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 53/260 (20%), Positives = 82/260 (31%), Gaps = 48/260 (18%)

Query: 194  PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGE 253
            PKP       +ST+    ++ P+K      G+   L V       K    +      +  
Sbjct: 2279 PKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSET 2338

Query: 254  ISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPP-AR 312
            +   P   V+  P   +       +GE             TF  +    +L SG+P  + 
Sbjct: 2339 VFDHPPSSVIALPMKEQLSTTYFTSGE-------------TFGQEKPASQLPSGSPSVSS 2385

Query: 313  FPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVD----- 367
             P  P       P+ +S   +   +    P   P PP     PPPP P  PP        
Sbjct: 2386 LPAKPR------PFFRSSSLDISAQPPPPPPPPPPPP--PPPPPPPPPPLPPPTSPKPTI 2437

Query: 368  ---------------------LTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPL 406
                                 +T    T+   S     T   TT+ PP PP   +    L
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGL 2497

Query: 407  PASHPSQPPVPSLPPRNIKP 426
              +H  +P  P + P+ + P
Sbjct: 2498 VFTHRPEPSKPPIAPKPVIP 2517



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 47/178 (26%), Positives = 63/178 (35%), Gaps = 36/178 (20%)

Query: 264  LKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSK---- 319
            +K A    G G+     E   D+K   A+ T   K +  E     PP+     P K    
Sbjct: 2301 VKKAKKETGNGIILEVLEAYRDKKELEAERT---KSSLSETVFDHPPSSVIALPMKEQLS 2357

Query: 320  ---LTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSS 376
                T G  +GQ  EK      S +P    LP         P+P          F ++SS
Sbjct: 2358 TTYFTSGETFGQ--EKPASQLPSGSPSVSSLPA-------KPRP----------FFRSSS 2398

Query: 377  GNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPV 434
             + +++          PPPPP  P   PP P   P  PP    P    K    + SPV
Sbjct: 2399 LDISAQPPP-------PPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPV 2449



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 39/179 (21%), Positives = 61/179 (34%), Gaps = 25/179 (13%)

Query: 265 KPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTP---PARFPKAP-SKL 320
           KP   + GPG     +  ++D    +  +    KI  +   +G P   P + P+   +KL
Sbjct: 217 KPIPKQQGPGR----DPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKL 272

Query: 321 TVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNST 380
            +           + D +    KQ  +    ++ P  P P++PP    T     +     
Sbjct: 273 PL-----------QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH 321

Query: 381 SKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQ 439
            K Q        P  PP+ P+      A  P     P  PP   KPP     P     Q
Sbjct: 322 EKSQPG------PAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 53/227 (23%), Positives = 76/227 (33%), Gaps = 47/227 (20%)

Query: 48   PAGPSNVP-------KFGSPKPPVAVKPSSEEKPDKEPKPPFL--KPTGAGQRFGTPASL 98
            P  PS++P       +    KPP+A KP   + P    KP  +  KPTG         +L
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNL 2546

Query: 99   TTRDPEAKVGFLKPVGPKP-----------------INLPKEDSKPT--------FPWPP 133
             T           P+ P                   I LP E   PT          WP 
Sbjct: 2547 VTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606

Query: 134  GNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLF 193
            G+ PS        DL  + P     PP +  E   +  +   + G    A Q     P+ 
Sbjct: 2607 GS-PS-------KDLVSVEPVFSVVPPVTAVEIPISSEQTFYISG----ALQTFSATPVT 2654

Query: 194  PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP 240
               +F Q  P S       E     VS+++ +   +G+ S S  + P
Sbjct: 2655 APSSF-QAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPP 2700



 Score = 31.2 bits (69), Expect = 4.1
 Identities = 44/163 (26%), Positives = 58/163 (35%), Gaps = 14/163 (8%)

Query: 24   TGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFL 83
            +G  S S + A+   F    +    A P   P    P PP    P     P   P P   
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP----PPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 84   KPTGAGQRFGTPAS-LTTRDP--EAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSL- 139
            KPT   ++  T AS +TT  P  +A          +   LP      T P P   KPS  
Sbjct: 2434 KPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSI 2493

Query: 140  -HSVNQDHDLKPLGPKSGPTP-----PTSENEQKQAFPKLTGV 176
               +   H  +P  P   P P     PT+  +     PK TG+
Sbjct: 2494 PSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGL 2536


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 116/478 (24%), Positives = 155/478 (32%), Gaps = 67/478 (14%)

Query: 26   PNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKP 85
            PN       R+     +     P  P   P+    + P    P+S   P    K    KP
Sbjct: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAK----KP 1200

Query: 86   TGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQD 145
             G G+  G  A       EA    L+P+ P  I L    +        G+  S      D
Sbjct: 1201 RGRGRGRGRKAE------EAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAIS----GTD 1250

Query: 146  HDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAF--GQKPP 203
            H+       S  T    E + K+   K   +K  FM++  D         P +  G  PP
Sbjct: 1251 HN----SLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPP 1306

Query: 204  LSTENSHEDESPMKNVSSSKGS------PAPLGVRSKSGPLKPAREDSENKDHAGEISSL 257
            LS   S     P + +     +      P P G     G L+ A  +       G     
Sbjct: 1307 LSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE-------GLGLGC 1359

Query: 258  PFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNT-FQSKINQEELASGTPPARFPK- 315
            P P   L     R    L     ++++      AKN   Q  I+    A   PP   PK 
Sbjct: 1360 PSPCKRLDEELKRNLETLPSFSSDEEDS----VAKNRDLQESISSAISALDDPPLAGPKD 1415

Query: 316  ---------APSKLTVGGPW--GQSQEKEKGDKNSATPKQKPLP---PLFTLGPPPPKPN 361
                     AP+    G P   G       G       ++KP P   P  T  P PP P 
Sbjct: 1416 TSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPP 1475

Query: 362  RPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPP 421
             PP   L            S       T S PPPPP  P   P +P+  P  PP P+  P
Sbjct: 1476 PPPQPALP-----------SPPPLVAPTPSSPPPPPLPPPPPPAMPS--PPPPPPPAAAP 1522

Query: 422  RNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEE 479
                PP +  +P  ED +   T         E     GET E+   S      RE++E
Sbjct: 1523 L-AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDE 1579



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 97/468 (20%), Positives = 147/468 (31%), Gaps = 63/468 (13%)

Query: 62   PPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLP 121
            PP+A  P     PD  P  P     G     G P++ +   PE  +   KP  P P   P
Sbjct: 1408 PPLA-GPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPP-PTPPPAP 1465

Query: 122  KEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFM 181
                +P  P PP  +P+L S        P  P   P PP          P          
Sbjct: 1466 TPQPQPPPP-PPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLA 1524

Query: 182  SASQDLEPKPLFPKPAFGQKP---PLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPL 238
            +  ++    P  P P   + P   PL      E  +         G     G+  +    
Sbjct: 1525 APPEE----PAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEF 1580

Query: 239  KPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRK-----IDAAKN 293
                ED  +   A +    P P   ++ A  +      K+G+ +             AKN
Sbjct: 1581 VIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKN 1640

Query: 294  TFQ-------SKINQEELAS--GTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQ 344
             +Q         +N+++        P   P  P + +     GQ++       +SA P +
Sbjct: 1641 RYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRS-----GQAKNPVSAGGSSAPPPK 1695

Query: 345  KPLPP------------------LFTLGPPPPKPNRP----PNVDLTKFHKTSSGNSTSK 382
             P PP                    T  P PP P +P    P     +  K + G    +
Sbjct: 1696 APAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLR 1755

Query: 383  GQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIK---PPFDLKSPVNEDNQ 439
            G+ + S     P        +  L    P+   +P   P  +K   PP   K  + E   
Sbjct: 1756 GERATSGRQTRP--------ERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGG 1807

Query: 440  DGVTHSDGAGNLDEEQDSEGETYEDIEASKER-EKKREKEEKKRLELE 486
            +        G+  + + S G   ED  A   R  K R   E  R  +E
Sbjct: 1808 NATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVE 1855



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 85/349 (24%), Positives = 108/349 (30%), Gaps = 68/349 (19%)

Query: 76   KEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGN 135
            K P PP   P  A     TP  L        +  + P  P P  LP   S    P P  +
Sbjct: 762  KSPPPP---PPTAQSTQPTPHGLLLEAGGPDLPLVLPP-PPPQLLPSVLSHAPSPSPSAS 817

Query: 136  KPSLHSVNQ-DHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFP 194
            K  +H +     D  P  P   P PP     Q +A  +           S  LEP     
Sbjct: 818  KVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLR-----------SHGLEPA---- 862

Query: 195  KPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEI 254
                   P L  E S +    M+ +  +     P    +  GP      +SE KD AG  
Sbjct: 863  ----APSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGP-----PNSEGKDPAGAY 913

Query: 255  SSLPFPGVVLK---PAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPA 311
             S    G       P  S   P      EE+          + F +    EE+  G    
Sbjct: 914  RSPSPQGTKAPRFVPLTSICFPDSLLQDEER----------SFFPT---MEEMFGGGAAD 960

Query: 312  RFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFT-----LGPPPP----KPNR 362
             + KA      G P  +   K         P   P  P         GP  P     PN+
Sbjct: 961  DYGKA------GPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNK 1014

Query: 363  PPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHP 411
            PP +        S+ N+   G          PPPP  P   PP PAS P
Sbjct: 1015 PPELP-------STVNAEPLGLIQSGPHQAAPPPPP-PPPPPPAPASEP 1055



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 28/114 (24%), Positives = 43/114 (37%), Gaps = 6/114 (5%)

Query: 310 PARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDL- 368
           P++ P  PS L      G       G   + TP  +P PP     PPPP  + P   +L 
Sbjct: 193 PSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPP----DPPPPPRHLPTQFNLL 248

Query: 369 -TKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPP 421
            +     ++   +S    ++S  +  PPPP     +      H  +P     PP
Sbjct: 249 ASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP 302



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 59/246 (23%), Positives = 92/246 (37%), Gaps = 36/246 (14%)

Query: 25  GPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLK 84
           GP++S  +    +   ++G    P+  S + +F SP    A+           P P  L 
Sbjct: 83  GPDAS--VMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHT---------PGPTELF 131

Query: 85  PTGAGQRFGTPASLTTRDPEAKVGFLKPV--GPKPINLPKEDSKPTFPW-PPGNKPSLHS 141
            +GA      P S T     A   +  P   G +P  +P   S    P+ PP N      
Sbjct: 132 ISGA-----LPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPAN-----G 181

Query: 142 VNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQK 201
           +   HD+  L P   PT P+S   ++ A   + G  G   + +    P P  P P     
Sbjct: 182 LLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPP----- 236

Query: 202 PP--LSTENSHEDESPMKNVSSSKGSPAPLGVRSKS-GPLKP----AREDSENKDHAGEI 254
           PP  L T+ +    S     ++ + SP        + GP  P     R+D+  K +    
Sbjct: 237 PPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPA 296

Query: 255 SSLPFP 260
           S+ P P
Sbjct: 297 SAQPPP 302


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 60.1 bits (144), Expect = 8e-09
 Identities = 84/322 (26%), Positives = 102/322 (31%), Gaps = 52/322 (16%)

Query: 111 KPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPT-PPTSENEQKQA 169
           KP GP P    +  +KP  P PPG KP       D    P  P   P  PP     Q Q 
Sbjct: 56  KPQGPPP----QGGNKPQGPPPPG-KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 110

Query: 170 FPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPL 229
            P   G          +    P  P P   Q PP   + S    SP          P P 
Sbjct: 111 PPPPPGKPQGPPPQGGNRPQGP--PPPGKPQGPPPQGDKSRSPRSP----PGKPQGPPPQ 164

Query: 230 GVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKID 289
           G     GP  P  +        G+    P P     P   +G P     G++ +      
Sbjct: 165 GGNQPQGPPPPPGKPQGPPPQGGKKPQGPPP-----PGKPQGPP---PQGDKSR------ 210

Query: 290 AAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPP 349
                          +S +PP + P+ P     GG   Q      G      P+    P 
Sbjct: 211 ---------------SSQSPPGK-PQGPPPQ--GGNQPQGPPPPPGKPQGPPPQGGNKPQ 252

Query: 350 LFTLGPPPP-KPNRPPNVDLTKFHKTSS--GNSTSKGQTSYSTTSLPPPPPSHPASQPPL 406
               GPPPP KP  PP    +K     S  G      Q   +    PPPP      QP  
Sbjct: 253 ----GPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 308

Query: 407 -PASHPSQPPVPSLPPRNIKPP 427
            PA  P  PP P    R  +PP
Sbjct: 309 PPAGQPQGPPRPPQGGRPSRPP 330



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 35/113 (30%), Positives = 45/113 (39%), Gaps = 8/113 (7%)

Query: 315 KAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPL-----FTLGPPPP-KPNRPP-NVD 367
           ++PS L  G P G S +     +    P  KP  P         GPPPP KP  PP   D
Sbjct: 27  ESPS-LIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 85

Query: 368 LTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP 420
            ++  ++  G          +    PPPPP  P   PP   + P  PP P  P
Sbjct: 86  KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP 138



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/249 (21%), Positives = 72/249 (28%), Gaps = 20/249 (8%)

Query: 205 STENSHEDESPMKNVSSSKGSP---APLGVRSKSGPLKPAREDSENKDHAGEISSLPFPG 261
           S +N +ED S  ++ S   G+P   +P G     GP  P  +        G     P P 
Sbjct: 15  SAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPP 74

Query: 262 VVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
              +    +G    S      K         N  Q          G PP    +      
Sbjct: 75  GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134

Query: 322 VGGPWGQSQEKEKG--------------DKNSATPKQKPLPPLFTLGPPPP---KPNRPP 364
            G P G   + +K                +    P+  P PP    GPPP    KP  PP
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPP 194

Query: 365 NVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNI 424
                +        S S           PP   + P   PP P      PP     P+  
Sbjct: 195 PPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 254

Query: 425 KPPFDLKSP 433
            PP   + P
Sbjct: 255 PPPGKPQGP 263



 Score = 37.4 bits (85), Expect = 0.058
 Identities = 49/181 (27%), Positives = 52/181 (28%), Gaps = 45/181 (24%)

Query: 15  SVNSRPFRVTGPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKP---PVAVKP--- 68
           S  S P +  GP    G Q        QG   PP  P   P  G  KP   P   KP   
Sbjct: 150 SPRSPPGKPQGPPPQGGNQP-------QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP 202

Query: 69  --------SSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINL 120
                   SS+  P K   PP   P G  Q  G P            G  KP GP P   
Sbjct: 203 PPQGDKSRSSQSPPGKPQGPP---PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 259

Query: 121 P---------KEDSKPTFPWPPGNKPSLHSVN------------QDHDLKPLGPKSGPTP 159
           P         K  S  + P  P   P     N            Q     P G   GP  
Sbjct: 260 PQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 319

Query: 160 P 160
           P
Sbjct: 320 P 320


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 110/494 (22%), Positives = 165/494 (33%), Gaps = 121/494 (24%)

Query: 67   KPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSK 126
            K    E P   P PP+L         G P    +R P      L+  GP+P+        
Sbjct: 819  KGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFP------LEEPGPRPL-------- 864

Query: 127  PTFPWPPGNK--------PSLHSVNQDHDLKPLGPKSG-------------PTPPTSENE 165
               PWPPG+         P      ++   +  GP++G             P PP  E+ 
Sbjct: 865  ---PWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESR 921

Query: 166  QKQAFPKLTGVKGKFMSASQDLEPK-PLFPKPAFG--QKPPLSTENSHEDESPMKNVSSS 222
             +  +    G      S+ + + P+ P  P    G  +KPP  T+       P++    +
Sbjct: 922  TETRWGPRPG------SSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDET 975

Query: 223  KGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEK 282
               P P  ++   G L   +E   N    G +S  P P +    +  R GP  S  G  +
Sbjct: 976  PKPPKPDPLKITKGKLGGPKETPPN----GNLS--PAPRLRRDYSYERVGP-TSCRGRGR 1028

Query: 283  KE-------------DRKIDAAKNTFQSKIN---QEELASGTPPARFPKAPSKLTVGGPW 326
             E              R   A    F+S       +    GT     P AP   T     
Sbjct: 1029 GEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETR 1088

Query: 327  GQSQEKEK-----------------------GDKNSATPKQKPLPPLFTLGPPPPKPNRP 363
             +  E E+                        DK + TPK+  L  +  L PPPP    P
Sbjct: 1089 SEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQV-PLAPPPP--GAP 1145

Query: 364  PNVDLTKFHKTSSGNSTSKGQTSYSTTSLP---------PPPPSHPASQPPLPASHPSQP 414
            P+    +F        T++G   ++   +P         PPP   P   PP  +  P +P
Sbjct: 1146 PSPAPARF--------TARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKP 1197

Query: 415  PVPSLPPRNIKPPFDLK---SPVNEDNQDGVTHSDGAGNLDEEQD---SEGETYEDIEAS 468
            P   LPP   K P   K    P++   + G       G  D E+      G   +  +  
Sbjct: 1198 PTGPLPPS--KEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPP 1255

Query: 469  KEREKKREKEEKKR 482
            + R  K+E+E   R
Sbjct: 1256 RFRRLKQERENAAR 1269



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 106/509 (20%), Positives = 180/509 (35%), Gaps = 87/509 (17%)

Query: 25  GPNSSSGIQARKNLFNNQGNASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLK 84
           GP+   G  ++ +  ++      P+GP   P +    PP    P     P   P+ P+  
Sbjct: 214 GPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRY 273

Query: 85  PTGAG-QRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFP---------WPPG 134
           PT  G  RF   A      P  ++  ++PVG +P ++ KED+   F          W   
Sbjct: 274 PTPDGPSRFPRVAGPRGSGPPMRL--VEPVG-RP-SILKEDNLKEFDQLDQENDDGWAGA 329

Query: 135 N-------KPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDL 187
           +       K          D    G +      ++  E++   P+  G KG   ++    
Sbjct: 330 HEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERP--PEADGKKGNSPNS---- 383

Query: 188 EPKPLFPKPAFGQ--KPPLSTENSHEDESPM----KNVSSSKGSPAPLGVRSKSGPLKPA 241
             +P  PK A+ +  +PP +       + P+    +  + + G P     R       PA
Sbjct: 384 --EPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPA 441

Query: 242 REDSEN------KDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNT- 294
            ED +       K  + EIS           A  R      +     +E+R+   A+   
Sbjct: 442 PEDEDEAWRQRRKQSSSEISL----------AVERARRRREEEERRMQEERRAACAEKLK 491

Query: 295 -FQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTL 353
               K    +      PA  P APS  T   P   +  KE     +  P   P P     
Sbjct: 492 RLDEKFGAPDKRLKAEPAAPPAAPS--TPAPP--PAVPKELPAPPAPPPASAPTPETEPE 547

Query: 354 GP---PPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASH 410
            P   PP +    P V       +  G+++S    S+  + + P  PS    +PP     
Sbjct: 548 EPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPP 607

Query: 411 PSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKE 470
           P+ PPVP + P+                       DG G    +  S+G  Y   + S  
Sbjct: 608 PTTPPVPKVEPK----------------------GDGIGP-TRQPPSQGLGYPKYQKSLP 644

Query: 471 REKKREKEEKKRLELEKKEQKEKEKKEQE 499
              +R+++E    +L K++Q+ + ++ Q+
Sbjct: 645 PRFQRQQQE----QLLKQQQQHQWQQHQQ 669



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 95/397 (23%), Positives = 133/397 (33%), Gaps = 65/397 (16%)

Query: 69  SSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPT 128
           S EE+P +        P        T  + T+R PE + G   P  PKP  LP     P 
Sbjct: 365 SGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPG---PPAPKP-PLPPPHRGPA 420

Query: 129 FPW-PPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENE-----QKQAFPKLTGVKGKFMS 182
             W PPG+ P              GP   P  P  E+E     +KQ+  +++    +   
Sbjct: 421 GNWGPPGDYPDRG-----------GPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARR 469

Query: 183 ASQDLEPKPLFPK-PAFGQKPPLSTENSHEDESPMKNVSSSK----GSPAPLGVRSKSGP 237
             ++ E +    +  A  +K     E     +  +K   ++      +PAP     K  P
Sbjct: 470 RREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELP 529

Query: 238 LKPA---------REDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKI 288
             PA           + E    A    S P PGV   P    GG   S       E   +
Sbjct: 530 APPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPV 589

Query: 289 DAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPK-QKPL 347
           +    + +     EE+   T P   PK   K    GP  Q   +  G      PK QK L
Sbjct: 590 EPQLPSKEGPEPPEEVPPPTTPP-VPKVEPKGDGIGPTRQPPSQGLG-----YPKYQKSL 643

Query: 348 PPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLP 407
           PP F          R     L K  +        +G  S   T +PP PP  P +   +P
Sbjct: 644 PPRF---------QRQQQEQLLKQQQQHQWQQHQQG--SAPPTPVPPSPPQ-PVTLGAVP 691

Query: 408 ASHPSQPP-----------VPSLPPRNIKPPFDLKSP 433
           A     PP            P +PP N  P + +  P
Sbjct: 692 APQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPP 728



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 93/407 (22%), Positives = 138/407 (33%), Gaps = 104/407 (25%)

Query: 41   NQGNASPPAGPSNVPKFGS-PKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLT 99
            ++ + +P    +  PK G+  + P+A  P     P   P P   + T  G R  TP  + 
Sbjct: 1113 HESDLAPSDKEAPTPKEGTLTQVPLAPPP-----PGAPPSPAPARFTARGGRVFTPRGVP 1167

Query: 100  TR--------DPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPL 151
            +R         P+   G+  P        P     PT P PP  +P    +     L P+
Sbjct: 1168 SRRGRGGGRPPPQVCPGWSPPAKSLAPKKP-----PTGPLPPSKEPLKEKLIPG-PLSPV 1221

Query: 152  -----------GPKSGPTPPTSEN---EQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPA 197
                       G + G  P    +   +Q+   P+   +K +  +A++  E KP    PA
Sbjct: 1222 ARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPA 1281

Query: 198  FGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSL 257
                P          E  +  V+ +   PAP    +KS  L     D  N++      S 
Sbjct: 1282 SAPGP----------EEALTTVTVA---PAPRRAAAKSPDLSNQNSDQANEEWETASESS 1328

Query: 258  PF-----------PGVVLKPAA--SRGG------PGLSKNGEEKKEDRKIDAAKNTFQSK 298
             F           P V+L P A  + GG      PG+S         R  D +K +F S+
Sbjct: 1329 DFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQ 1388

Query: 299  INQEELASGTPPARFPKAPSKLTVGGPWGQSQEKE---KGDKNS-ATPKQKPLPPLFTLG 354
                E  +  P        S  + GG  G    +    +GDK S  +PK +  PP     
Sbjct: 1389 RPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPP----- 1443

Query: 355  PPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPA 401
                   RPP + L                        PPPPPS  A
Sbjct: 1444 -----EERPPGLPL------------------------PPPPPSSSA 1461



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 91/390 (23%), Positives = 140/390 (35%), Gaps = 88/390 (22%)

Query: 132 PPGNKPSLHSVNQDHDLK-PLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPK 190
           PP N PSL + N+ +D    L PK G       ++Q+Q+ PK +       +   + +P 
Sbjct: 58  PPANLPSLKAENKGNDPNVSLVPKDG---TGWASKQEQSDPKSSDAS---TAQPPESQPL 111

Query: 191 PLFPKPAFGQ--KPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENK 248
           P    PA  Q  +PP + EN     +P+           P GV+S +     A       
Sbjct: 112 PASQTPASNQPKRPPAAPEN-----TPL----------VPSGVKSWA----QASVTHGAH 152

Query: 249 DHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGT 308
              G  SSL      L   +    P L   G++ K  ++ ++A           E +SG 
Sbjct: 153 GDGGRASSL------LSRFSREEFPTLQAAGDQDKAAKERESA-----------EQSSGP 195

Query: 309 PPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNR---PPN 365
            P+  P+  +    GG  G+  ++ +G  +       P   L   GPP   P R   PP 
Sbjct: 196 GPSLRPQNSTTWRDGG--GRGPDELEGPDSKLHHGHDPRGGLQPSGPPQFPPYRGMMPPF 253

Query: 366 VDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPAS--QPPLPASHPSQPPVPSLPPRN 423
           +                         LP PPP  P    + P P      P V    PR 
Sbjct: 254 M---------------------YPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAG--PRG 290

Query: 424 IKPPFDLKSPVNEDN---QDGVTHSDGAGNLDEEQD-------SEGETYEDIEASKEREK 473
             PP  L  PV   +   +D +   D    LD+E D        E +  E ++ S E + 
Sbjct: 291 SGPPMRLVEPVGRPSILKEDNLKEFD---QLDQENDDGWAGAHEEVDYTEKLKFSDEEDG 347

Query: 474 KREKEEKKRLELEKKEQKEKEKKEQEIKKK 503
           +   EE      + +    +E+  +   KK
Sbjct: 348 RDSDEEGAEGHRDSQSASGEERPPEADGKK 377



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 32/133 (24%), Positives = 47/133 (35%), Gaps = 12/133 (9%)

Query: 357 PPKPNRP----------PNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPL 406
           PP  N P          PNV L     T   +   +     S  S   PP S P      
Sbjct: 57  PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116

Query: 407 PASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIE 466
           PAS+  + P P+ P      P  +KS        G  H DG            E +  ++
Sbjct: 117 PASNQPKRP-PAAPENTPLVPSGVKSWAQASVTHG-AHGDGGRASSLLSRFSREEFPTLQ 174

Query: 467 ASKEREKKREKEE 479
           A+ +++K  ++ E
Sbjct: 175 AAGDQDKAAKERE 187



 Score = 30.4 bits (67), Expect = 7.0
 Identities = 70/327 (21%), Positives = 107/327 (32%), Gaps = 65/327 (19%)

Query: 115  PKPINLPKEDSKPTFPWPPG--NKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPK 172
            PK  + P E+  P  P PP   +  ++  ++Q     P G +             QA  +
Sbjct: 1436 PKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQ-------------QALAQ 1482

Query: 173  LTGVKGKFMSASQDLEPKPLFPKPAFGQKPP-------------LSTENSHEDESPMKNV 219
            L+  +G   +       KP  P+   G  P              LS++   E+  PM  V
Sbjct: 1483 LSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPM--V 1540

Query: 220  SSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNG 279
                G+P      S   P +  RE    K    +  SLP P       +   GPG     
Sbjct: 1541 RGVGGTPRDSAGVSPFPPKR--RERPPRKPELLQEESLPPPHSSGFLGSKPEGPG----P 1594

Query: 280  EEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNS 339
            + +  D   +A      ++++       T  +R    PS +    PW             
Sbjct: 1595 QAESRDTGTEALTPHIWNRLH-------TATSRKSYRPSSME---PW------------- 1631

Query: 340  ATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH 399
                 +PL P   +       +    VDL+   + SSG  + +             PP  
Sbjct: 1632 ----MEPLSPFEDVAGTEMSQS-DSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKR 1686

Query: 400  PASQPPLPASHPSQPPVPSLPPRNIKP 426
            P    PL A  P + P  S PPR   P
Sbjct: 1687 PGGSSPLNAV-PCEGPPGSEPPRRPPP 1712


>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
           sapiens]
          Length = 956

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 100/448 (22%), Positives = 173/448 (38%), Gaps = 48/448 (10%)

Query: 348 PPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLP 407
           P + +L   P   N  P  ++ +         +    +S S+TS P  PP+ P       
Sbjct: 251 PQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQ----- 305

Query: 408 ASHPSQPPVP-SLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGN---LDEEQDSEGETYE 463
             H S  P P S P R I   F +K    ++        +  G    L  E++ + +  E
Sbjct: 306 --HSSTSPFPTSTPLRRITKKF-VKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKE 362

Query: 464 DIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFKLTGPIQVIHLAKACCDVK 523
           + + +KE  KK+++EEK+  E E++E++EK++KE+  K++ K     +     +A  + K
Sbjct: 363 EAKRAKEEAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEK 422

Query: 524 GGKNELSFK-------QGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTAVEIDYDSLKL 576
             K E           + E+ EI R    P+     +T  GS G      ++ ++  L  
Sbjct: 423 RKKEEEKRLREEEKRIKAEKAEITRFFQKPKTPQAPKTLAGSCGKFAPFEIK-EHMVLAP 481

Query: 577 KKDSLGAPSRPIEDDQEVYDDVAE---QDDISSHSQSGSGGIFPPPPDDDIYDG---IEE 630
           ++ +   P    + DQ +     E     D+       SG       + DI++    I E
Sbjct: 482 RRRTAFHPDLCSQLDQLLQQQSGEFSFLKDLKGRQPLRSGPTHVSTRNADIFNSDVVIVE 541

Query: 631 EDADDG----------STLQVQEKSNTWSWGI----LKMLKGKDDRKKSIREKPKVSDSD 676
               DG            LQ  E      WG       +++ +D   +  +      DSD
Sbjct: 542 RGKGDGVPERRKFGRMKLLQFCENHRPAYWGTWNKKTALIRARDPWAQDTKLLDYEVDSD 601

Query: 677 NNEGSSFPAPP---KQLDMGDEVYDDVDTSD-FPVSSAEMSQGTNVGKAKTEEKDLK-KL 731
                  P       + D  D++ +D D  D F V    +S+   V +   + ++ K + 
Sbjct: 602 EEWEEEEPGESLSHSEGDDDDDMGEDEDEDDGFFVPHGYLSEDEGVTEECADPENHKVRQ 661

Query: 732 KKQEKEEKDFRKKFKYDGEIRVLYSTKV 759
           K + KE  +F  K K     RVL   K+
Sbjct: 662 KLKAKEWDEFLAKGK---RFRVLQPVKI 686


>gi|148727255 microtubule associated serine/threonine kinase family
            member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 105/438 (23%), Positives = 157/438 (35%), Gaps = 79/438 (18%)

Query: 53   NVPKFGSPKPPVAVKPSSEEKPDKEPKPPF----LKPTGAGQRFGTPASLTTRDPEAKVG 108
            ++ K G+ +P    +P  +  P   P PP     L    A Q   +P+  + R+P AK  
Sbjct: 1921 SLQKDGAKEPERKEQPL-QRHPSSIPPPPLTAKDLSSPAARQHCSSPSHASGREPGAK-- 1977

Query: 109  FLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPT----PPTSEN 164
               P   +P + P++  KP          + HS +  H  +P GP  GP     P  S +
Sbjct: 1978 ---PSTAEPSSSPQDPPKPV---------AAHSESSSHKPRP-GPDPGPPKTKHPDRSLS 2024

Query: 165  EQKQAFPKLTGVKGKFMSASQDL------------EPKPLFP---------KPAFGQKPP 203
             QK   P +   KGK   A+Q L                +FP             GQ   
Sbjct: 2025 SQK---PSVGATKGK-EPATQSLGGSSREGKGHSKSGPDVFPATPGSQNKASDGIGQGEG 2080

Query: 204  LSTENSHEDESPMKNVSSSKGSPAPLGVRSKS---------GPLKPAREDSENKDHAGEI 254
              +   H D +P+           PL V  K          GP +PA    +     GE 
Sbjct: 2081 GPSVPLHTDRAPLDAKPQPTSGGRPLEVLEKPVHLPRPGHPGPSEPA---DQKLSAVGEK 2137

Query: 255  SSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASG---TPPA 311
             +L       KP+  +  P L K  + ++ D      K+  Q   N +  A G   T   
Sbjct: 2138 QTLSPKHP--KPSTVKDCPTLCKQTDNRQTD------KSPSQPAANTDRRAEGKKCTEAL 2189

Query: 312  RFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKF 371
              P    KL  G  +  S+ + KG +  A    K  P     GP P KP  P   D    
Sbjct: 2190 YAPAEGDKLEAGLSFVHSENRLKGAERPAAGVGKGFPEARGKGPGPQKP--PTEADKPNG 2247

Query: 372  HKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPAS--HPSQPPVPSLPPRNIKPPFD 429
             K S    ++ GQ+S+ +T+LP    S  +S P   A     S     +   +      +
Sbjct: 2248 MKRS---PSATGQSSFRSTALPEKSLSCSSSFPETRAGVREASAASSDTSSAKAAGGMLE 2304

Query: 430  LKSPVNEDNQDGVTHSDG 447
            L +P N D++      +G
Sbjct: 2305 LPAPSNRDHRKAQPAGEG 2322



 Score = 32.7 bits (73), Expect = 1.4
 Identities = 28/117 (23%), Positives = 48/117 (41%), Gaps = 15/117 (12%)

Query: 331  EKEKGDKNSATP------------KQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGN 378
            E EK +K S+ P            K++PL    +  PPPP   +  +    + H +S  +
Sbjct: 1909 ESEKSEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAKDLSSPAARQHCSSPSH 1968

Query: 379  STSKGQTSYSTTSLP---PPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKS 432
            ++ +   +  +T+ P   P  P  P +     +SH  +P     PP+   P   L S
Sbjct: 1969 ASGREPGAKPSTAEPSSSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSS 2025



 Score = 30.4 bits (67), Expect = 7.0
 Identities = 74/365 (20%), Positives = 114/365 (31%), Gaps = 66/365 (18%)

Query: 132  PPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKP 191
            P  +K  L S        P G      PP          P  +G K    SA ++L P  
Sbjct: 1624 PQASKTELPSPESAQSPSPSGDVRASVPPV--------LPSSSGKKNDTTSA-RELSPSS 1674

Query: 192  LFPKPAFGQKP-----PLSTENSHEDESPMKNVSSSKGSPAPL----GVRSKSGPLKPAR 242
            L    ++  +P         +NS     P       +  P P     G   +S P +   
Sbjct: 1675 LKMNKSYLLEPWFLPPSRGLQNSPAVSLPDPEFKRDRKGPHPTARSPGTVMESNPQQREG 1734

Query: 243  EDSENKDHAGEIS------------SLPFPGVVLKPAAS--RGGPGLSKNGEE------- 281
               +++DH  +               L  P   L P AS  R  PGL ++ E        
Sbjct: 1735 SSPKHQDHTTDPKLLTCLGQNLHSPDLARPRCPLPPEASPSREKPGLRESSERGPPTARS 1794

Query: 282  KKEDRKIDAAKN---------TFQSKINQEELAS--GTPPARFPKAPSKLTVGGPWGQSQ 330
            ++   + D  +          T ++  N + L S   T P  + +  +      P G++ 
Sbjct: 1795 ERSAARADTCREPSMELCFPETAKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGGKTN 1854

Query: 331  EKEKGDKNSATPKQKPLPPLFTLGPPPPKP--------NRPPNVDLTKFHKTSSGNSTSK 382
             K+      A P  +    L + G P  K            P   L +      G  + K
Sbjct: 1855 HKD--GPGEARPPPRDNSSLHSAGIPCEKELGKVRRGVEPKPEALLARRSLQPPGIESEK 1912

Query: 383  GQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGV 442
             +   S  SL       P  +      HPS  P P L  +      DL SP    +    
Sbjct: 1913 SEKLSSFPSLQKDGAKEPERKEQPLQRHPSSIPPPPLTAK------DLSSPAARQHCSSP 1966

Query: 443  THSDG 447
            +H+ G
Sbjct: 1967 SHASG 1971


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 82/370 (22%), Positives = 131/370 (35%), Gaps = 34/370 (9%)

Query: 47  PPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRDPEAK 106
           P   PS      SP+PP +V     +K    P P   KP          A+L+   P+ +
Sbjct: 172 PSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPE-SVKATLSNPKPQKQ 230

Query: 107 VGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQ 166
             F + +GP   + P+       P P G  P+  S       +   P+     P+   E 
Sbjct: 231 SHFPETLGPPSASSPESPVLAASPEPWGPSPAA-SPESRKSARTTSPEPRKPSPSESPEP 289

Query: 167 KQAFPKLTGVKGKFMSASQDLEPKPLFP-KPAFGQKPPLSTENSHEDESPMKNVSSSKGS 225
            + FP ++    +   A      KP  P  P   +  P ++    +   P  +VS     
Sbjct: 290 WKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWK 349

Query: 226 PAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKED 285
           P P       GP KP    S     +  +S   +      P + + GP          E 
Sbjct: 350 PIP---SVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGP---------PEL 397

Query: 286 RKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQK 345
           RK         S  + + +   +P  R P  P    +  P G  + +          K  
Sbjct: 398 RKTAPT----LSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELR----------KPS 443

Query: 346 PLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPP 405
             P L+ L P   K + P ++D  +  K+S G S    ++S+    + P  P  P ++ P
Sbjct: 444 GSPDLWKLSPDQRKTS-PASLDFPESQKSSRGGSPDLWKSSF---FIEPQKPVFPETRKP 499

Query: 406 LPASHPSQPP 415
            P S PS+ P
Sbjct: 500 GP-SGPSESP 508



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 45/159 (28%), Positives = 57/159 (35%), Gaps = 37/159 (23%)

Query: 301 QEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFT------LG 354
           + +L   T P + P  P             E +K   NSA PK  P   + T      L 
Sbjct: 96  KNQLNKETDPVKSPPLP-------------EHQKIPCNSAEPKSIPALSMETQKLGSVLS 142

Query: 355 PPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPA--SQPPLPASHP- 411
           P  PKP       LT       G+  S        T LP P PS PA  S P  P S P 
Sbjct: 143 PESPKPT-----PLTPLEPQKPGSVVSPELQ----TPLPSPEPSKPASVSSPEPPKSVPV 193

Query: 412 ----SQPPVPSLPPRNIKP--PFDLKSPVNEDNQDGVTH 444
                  PVPS  P+   P  P  +K+ ++       +H
Sbjct: 194 CESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSH 232


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 121/553 (21%), Positives = 189/553 (34%), Gaps = 73/553 (13%)

Query: 22  RVTGPNSSSGIQARKNLFNNQGNASPPA----GPSNVPKFGSPKPPVAVKPSSEEKPDKE 77
           R   P+   G  +     N++G++ P        S  P   SP+   +   SS ++   +
Sbjct: 122 RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 181

Query: 78  PKPPFLK-PTG-----AGQRFGTPASLTTRDPEAKVGFLKPVG-PKPINLPKEDSKPTFP 130
            +PP L+ PTG     +    GTP  L T  P      + P G P     P +   PT P
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 240

Query: 131 WP-----------PGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV--- 176
            P           P   PS H         PL P +G     S     Q  P L G    
Sbjct: 241 VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 298

Query: 177 ------KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG 230
                  G  +      +P  L P+ + GQ P  ++  +    + ++  +S     +   
Sbjct: 299 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 358

Query: 231 VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDA 290
            R +  P  P             I  LP P     P    G    S N           A
Sbjct: 359 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP----A 414

Query: 291 AKNTFQSKINQEELASGTPPARFPKA-PSKLTVGGPWGQSQEKEKGDKNSATP-----KQ 344
            K       +    A   P    P++ P   +   P G +Q +      ++ P     + 
Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474

Query: 345 KPLPPLFTL-----GPPP------PKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLP 393
            P PP         GPPP      P  + PP    T      SG + S G  +   +S P
Sbjct: 475 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA-GGSSCP 533

Query: 394 PPP----------PSHPASQPPLPASHPSQPPV---PSLPPRNIKPPFDLKSPVNEDNQD 440
            P              P S PP P S   +P V   PS   ++ +    L    N   + 
Sbjct: 534 LPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCART 593

Query: 441 GVTHSDGAGNL----DEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKK 496
            +     AG+      EE   + +   + +A +ERE+++EKE+++  E E++ + E+  K
Sbjct: 594 DLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAK 653

Query: 497 EQEIKKKFKLTGP 509
                 + +L+ P
Sbjct: 654 ASSSAHEGRLSDP 666



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 87/428 (20%), Positives = 143/428 (33%), Gaps = 67/428 (15%)

Query: 47  PPAGPSNVPKFGSPK----PPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
           PP  P  +P+  +P+    PP    PS        P PP LKP  +      P++     
Sbjct: 377 PPTTP--IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP-- 432

Query: 103 PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKP--SLHSVNQD-----HDLKPLGPK- 154
           P   +   +P+   P   P        P PP + P   LH V        H   P GP  
Sbjct: 433 PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 492

Query: 155 -------SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTE 207
                  S  TPP       Q  P  +G      ++   +      P P    K   + +
Sbjct: 493 ITPPTCPSTSTPPAGPGTSAQ--PPCSGAA----ASGGSIAGGSSCPLPTVQIKEE-ALD 545

Query: 208 NSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAR-----EDSENKDHAGEISSLPFPGV 262
           ++ E ESP     S   SP P  V + S   + AR     +   N     ++  +P  G 
Sbjct: 546 DAEEPESPPPPPRSP--SPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 603

Query: 263 VLKPAASRGGPGLSKNGEEK-KEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
            L            +  E+K +E+R+ +  K   + +  + E        R  +  +K +
Sbjct: 604 KLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERE--------REAERAAKAS 655

Query: 322 VGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTS 381
                G+  + +        P  +P P      PP   P+ P    L+++ +    + T+
Sbjct: 656 SSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTN 715

Query: 382 KGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----------------NIK 425
           +    Y      P  P+ P     +P  +   P +     R                 +K
Sbjct: 716 RNHPFYM-----PLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMK 770

Query: 426 PPFDLKSP 433
           P F++K P
Sbjct: 771 PGFEVKPP 778


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 121/553 (21%), Positives = 189/553 (34%), Gaps = 73/553 (13%)

Query: 22   RVTGPNSSSGIQARKNLFNNQGNASPPA----GPSNVPKFGSPKPPVAVKPSSEEKPDKE 77
            R   P+   G  +     N++G++ P        S  P   SP+   +   SS ++   +
Sbjct: 676  RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735

Query: 78   PKPPFLK-PTG-----AGQRFGTPASLTTRDPEAKVGFLKPVG-PKPINLPKEDSKPTFP 130
             +PP L+ PTG     +    GTP  L T  P      + P G P     P +   PT P
Sbjct: 736  AQPPALQAPTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 131  WP-----------PGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV--- 176
             P           P   PS H         PL P +G     S     Q  P L G    
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852

Query: 177  ------KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG 230
                   G  +      +P  L P+ + GQ P  ++  +    + ++  +S     +   
Sbjct: 853  GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 912

Query: 231  VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDA 290
             R +  P  P             I  LP P     P    G    S N           A
Sbjct: 913  PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP----A 968

Query: 291  AKNTFQSKINQEELASGTPPARFPKA-PSKLTVGGPWGQSQEKEKGDKNSATP-----KQ 344
             K       +    A   P    P++ P   +   P G +Q +      ++ P     + 
Sbjct: 969  LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028

Query: 345  KPLPPLFTL-----GPPP------PKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLP 393
             P PP         GPPP      P  + PP    T      SG + S G  +   +S P
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA-GGSSCP 1087

Query: 394  PPP----------PSHPASQPPLPASHPSQPPV---PSLPPRNIKPPFDLKSPVNEDNQD 440
             P              P S PP P S   +P V   PS   ++ +    L    N   + 
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCART 1147

Query: 441  GVTHSDGAGNL----DEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKK 496
             +     AG+      EE   + +   + +A +ERE+++EKE+++  E E++ + E+  K
Sbjct: 1148 DLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAK 1207

Query: 497  EQEIKKKFKLTGP 509
                  + +L+ P
Sbjct: 1208 ASSSAHEGRLSDP 1220



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 87/428 (20%), Positives = 143/428 (33%), Gaps = 67/428 (15%)

Query: 47   PPAGPSNVPKFGSPK----PPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
            PP  P  +P+  +P+    PP    PS        P PP LKP  +      P++     
Sbjct: 931  PPTTP--IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP-- 986

Query: 103  PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKP--SLHSVNQD-----HDLKPLGPK- 154
            P   +   +P+   P   P        P PP + P   LH V        H   P GP  
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046

Query: 155  -------SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTE 207
                   S  TPP       Q  P  +G      ++   +      P P    K   + +
Sbjct: 1047 ITPPTCPSTSTPPAGPGTSAQ--PPCSGAA----ASGGSIAGGSSCPLPTVQIKEE-ALD 1099

Query: 208  NSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAR-----EDSENKDHAGEISSLPFPGV 262
            ++ E ESP     S   SP P  V + S   + AR     +   N     ++  +P  G 
Sbjct: 1100 DAEEPESPPPPPRSP--SPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 1157

Query: 263  VLKPAASRGGPGLSKNGEEK-KEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
             L            +  E+K +E+R+ +  K   + +  + E        R  +  +K +
Sbjct: 1158 KLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERE--------REAERAAKAS 1209

Query: 322  VGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTS 381
                 G+  + +        P  +P P      PP   P+ P    L+++ +    + T+
Sbjct: 1210 SSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTN 1269

Query: 382  KGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----------------NIK 425
            +    Y      P  P+ P     +P  +   P +     R                 +K
Sbjct: 1270 RNHPFYM-----PLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMK 1324

Query: 426  PPFDLKSP 433
            P F++K P
Sbjct: 1325 PGFEVKPP 1332


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 121/553 (21%), Positives = 189/553 (34%), Gaps = 73/553 (13%)

Query: 22   RVTGPNSSSGIQARKNLFNNQGNASPPA----GPSNVPKFGSPKPPVAVKPSSEEKPDKE 77
            R   P+   G  +     N++G++ P        S  P   SP+   +   SS ++   +
Sbjct: 676  RPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQ 735

Query: 78   PKPPFLK-PTG-----AGQRFGTPASLTTRDPEAKVGFLKPVG-PKPINLPKEDSKPTFP 130
             +PP L+ PTG     +    GTP  L T  P      + P G P     P +   PT P
Sbjct: 736  AQPPALQAPTGVTPAPSSAPPGTP-QLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAP 794

Query: 131  WP-----------PGNKPSLHSVNQDHDLKPLGPKSGPTPPTSENEQKQAFPKLTGV--- 176
             P           P   PS H         PL P +G     S     Q  P L G    
Sbjct: 795  VPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQ--PPLHGQGPP 852

Query: 177  ------KGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLG 230
                   G  +      +P  L P+ + GQ P  ++  +    + ++  +S     +   
Sbjct: 853  GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQP 912

Query: 231  VRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDA 290
             R +  P  P             I  LP P     P    G    S N           A
Sbjct: 913  PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPP----A 968

Query: 291  AKNTFQSKINQEELASGTPPARFPKA-PSKLTVGGPWGQSQEKEKGDKNSATP-----KQ 344
             K       +    A   P    P++ P   +   P G +Q +      ++ P     + 
Sbjct: 969  LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028

Query: 345  KPLPPLFTL-----GPPP------PKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLP 393
             P PP         GPPP      P  + PP    T      SG + S G  +   +S P
Sbjct: 1029 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA-GGSSCP 1087

Query: 394  PPP----------PSHPASQPPLPASHPSQPPV---PSLPPRNIKPPFDLKSPVNEDNQD 440
             P              P S PP P S   +P V   PS   ++ +    L    N   + 
Sbjct: 1088 LPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCART 1147

Query: 441  GVTHSDGAGNL----DEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKK 496
             +     AG+      EE   + +   + +A +ERE+++EKE+++  E E++ + E+  K
Sbjct: 1148 DLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAK 1207

Query: 497  EQEIKKKFKLTGP 509
                  + +L+ P
Sbjct: 1208 ASSSAHEGRLSDP 1220



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 87/428 (20%), Positives = 143/428 (33%), Gaps = 67/428 (15%)

Query: 47   PPAGPSNVPKFGSPK----PPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD 102
            PP  P  +P+  +P+    PP    PS        P PP LKP  +      P++     
Sbjct: 931  PPTTP--IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPP-- 986

Query: 103  PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKP--SLHSVNQD-----HDLKPLGPK- 154
            P   +   +P+   P   P        P PP + P   LH V        H   P GP  
Sbjct: 987  PLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPP 1046

Query: 155  -------SGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTE 207
                   S  TPP       Q  P  +G      ++   +      P P    K   + +
Sbjct: 1047 ITPPTCPSTSTPPAGPGTSAQ--PPCSGAA----ASGGSIAGGSSCPLPTVQIKEE-ALD 1099

Query: 208  NSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAR-----EDSENKDHAGEISSLPFPGV 262
            ++ E ESP     S   SP P  V + S   + AR     +   N     ++  +P  G 
Sbjct: 1100 DAEEPESPPPPPRSP--SPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 1157

Query: 263  VLKPAASRGGPGLSKNGEEK-KEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLT 321
             L            +  E+K +E+R+ +  K   + +  + E        R  +  +K +
Sbjct: 1158 KLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERE--------REAERAAKAS 1209

Query: 322  VGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTS 381
                 G+  + +        P  +P P      PP   P+ P    L+++ +    + T+
Sbjct: 1210 SSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTN 1269

Query: 382  KGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPR----------------NIK 425
            +    Y      P  P+ P     +P  +   P +     R                 +K
Sbjct: 1270 RNHPFYM-----PLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMK 1324

Query: 426  PPFDLKSP 433
            P F++K P
Sbjct: 1325 PGFEVKPP 1332


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 35/115 (30%), Positives = 57/115 (49%), Gaps = 6/115 (5%)

Query: 391 SLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGN 450
           S PPP P  P++  P P S  ++P  P L    +  P D +   + + ++G    DGA  
Sbjct: 15  SPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDRE---DGELEEGELEDDGA-- 69

Query: 451 LDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFK 505
            +E QD+ G      +   E+      EEK    L++K +KE+EK+++  KK+ K
Sbjct: 70  -EETQDTSGGPERSRKEKGEKHHSDSDEEKSHRRLKRKRKKEREKEKRRSKKRRK 123



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 98/443 (22%), Positives = 146/443 (32%), Gaps = 102/443 (23%)

Query: 46   SPPAGPSNVPKFGSPKPPV-------AVKPSSEEKP-DKEPKPPFLKPTGAGQRFG-TPA 96
            S P GPS+    GS  PP        A++  +   P D  P  P   P    Q+F     
Sbjct: 907  SSPVGPSSSK--GSGPPPTEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKK 964

Query: 97   SLTTRDPE-AKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLH-SVNQDHDLKPLGPK 154
             +T   P  A+     P    P+ +PK+D+ P  P    + P+L   +++     P   +
Sbjct: 965  DVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAGPPNAR 1024

Query: 155  SGPTPPTSENEQKQAFPK-------LTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTE 207
              P   T  + Q    P        L  V     SA+     KP  P+       P    
Sbjct: 1025 QRPGASTDSSTQGANLPDFELLSRILKTVNATGSSAAPGSSDKPSDPRVRKAPTDP---- 1080

Query: 208  NSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPF-PGVVLKP 266
                 + P  + +SS+         +K GP +     +     A   ++ P+ P V+   
Sbjct: 1081 ---RLQKPTDSTASSRA--------AKPGPAEAPSPTASPSGDASPPATAPYDPRVLAAG 1129

Query: 267  AASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTP--PARFPKAPSKLT--V 322
               +GG G                          Q  + SG      R P A  K T   
Sbjct: 1130 GLGQGGGG-------------------------GQSSVLSGISLYDPRTPNAGGKATEPA 1164

Query: 323  GGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSK 382
                 Q +  E   K+SA+                 K   PP V  +   +  +G + + 
Sbjct: 1165 ADTGAQPKGAEGNGKSSAS-----------------KAKEPPFVRKSALEQPETGKAGAD 1207

Query: 383  GQT---SYSTTSLPPP----PPSHPASQPPLPASHPSQP-----PVPSL-------PPRN 423
            G T    Y++ + P P     P+   + PP P   P QP     PVP+L       P   
Sbjct: 1208 GGTPTDRYNSYNRPRPKAAAAPAATTATPP-PEGAPPQPGVHNLPVPTLFGTVKQTPKTG 1266

Query: 424  IKPPFDLKSPVNEDNQDGVTHSD 446
               PF   SP  E  QD  +  D
Sbjct: 1267 SGSPFAGNSPAREGEQDAASLKD 1289



 Score = 34.3 bits (77), Expect = 0.49
 Identities = 27/85 (31%), Positives = 32/85 (37%), Gaps = 11/85 (12%)

Query: 330 QEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYST 389
           +E E+  K    P  KP PP   L P PP+P  P          TS      +G      
Sbjct: 494 KEVEELKKQGINPLPKP-PPGVGLLPTPPRPPGPQA-------PTSPNGRPMQGGPPPPP 545

Query: 390 TSLPPPPPSHPASQPPLPASHPSQP 414
              PPPPP     Q P+P   P  P
Sbjct: 546 ---PPPPPPPGPPQMPMPVHEPLSP 567



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 114/507 (22%), Positives = 164/507 (32%), Gaps = 156/507 (30%)

Query: 48   PAGPSNVPKFGSPKPPVAVKPSSEEKPD-----KEPKPP-------------------FL 83
            P  P+  P  G P PP    P     P       EP  P                    +
Sbjct: 529  PTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEIVV 588

Query: 84   KPTG-----AGQRFGTPASLTTRDPEAKVGFLKPVGPKP-INLPKEDSKPTFP-WPPGNK 136
            +PTG      G RF  P            G   P+GP P +  P     P  P   P   
Sbjct: 589  RPTGQLAEKLGVRFPGPG-----------GPPGPMGPGPNMGPPGPMGGPMHPDMHPDMH 637

Query: 137  PSLH-SVNQD-HDLKPLGPKSGPTPPTS------------------------------EN 164
            P +H  ++ D H   P+GP   P PP                                EN
Sbjct: 638  PDMHPDMHADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYEN 697

Query: 165  EQKQA------------------FPKLTGVKGKFMSASQDLEP-------KPLFPKPAFG 199
              +Q                   + +L G  G+ +     LEP        P  PKP  G
Sbjct: 698  FYQQQEGMEMEPGLLGDAEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRPKPGAG 757

Query: 200  QKPPLST-----------ENSHEDESPMKNVSSSK--------------GSPAPLGVRSK 234
                L +           +   E+E   +   SSK               S    G  S 
Sbjct: 758  VPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSV 817

Query: 235  SGPLKPAREDSENKDHA--GEISSLPFPGVVLK---PAASR-GGPGLSKNGEEKKEDRKI 288
            +  LK  R+ + ++  A  GE+SS       L+   P  SR   P LS+   + +  R +
Sbjct: 818  TSILKTLRQQTSSRPPASVGELSSSGLGDPRLQKGHPTGSRLADPRLSR---DPRLTRHV 874

Query: 289  DAA--KNTFQSKINQEELASGTPPAR-------FPKAPSKLTVGGPWGQSQEKEKGDKNS 339
            +A+       S  +   LA   P ++        P  PS     GP     E+E+G++ +
Sbjct: 875  EASGGSGPGDSGPSDPRLARALPTSKPEGSLHSSPVGPSSSKGSGP--PPTEEEEGER-A 931

Query: 340  ATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTS----YSTTSLPPP 395
               K   +P    L P P  P R P   L +F       + SK   +    ++   L P 
Sbjct: 932  LREKAVNIP----LDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPL 987

Query: 396  PPSHPASQPPLPASHPSQPPVPSLPPR 422
            P     + PP+PA+  S   +P+L PR
Sbjct: 988  PIPKQDAVPPVPAALQS---MPTLDPR 1011



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 25/95 (26%), Positives = 35/95 (36%), Gaps = 8/95 (8%)

Query: 346 PLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSL---PPPPPSHPAS 402
           P PP     PPPP P  PP + +      S      +   +    SL      P    A 
Sbjct: 542 PPPP-----PPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEIVVRPTGQLAE 596

Query: 403 QPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNED 437
           +  +    P  PP P  P  N+ PP  +  P++ D
Sbjct: 597 KLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPD 631


>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
           sapiens]
          Length = 2997

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 113/519 (21%), Positives = 185/519 (35%), Gaps = 112/519 (21%)

Query: 47  PPAGPSNVPKFGSPKPPVAVKPSSEEKPDK--------EPKPPFLKP--TGAGQRFGTPA 96
           PP  P       +  PP  V+P S   P +         P+P    P   G GQR   P 
Sbjct: 394 PPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNMPHPQPSHQPPGAMGIGQRNMGPR 453

Query: 97  SLT--------TRDPEAKVGFLKPVGPKPINL--PKEDSKPTFPWP--PGNKPSLHSVNQ 144
           ++         +  P    G ++P G   + L  P+   +   P    PG +PS   +  
Sbjct: 454 NMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHPGQQPSFQQLPT 513

Query: 145 DHDLKPLGPKSGPTPPTSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPL 204
              L+P       + P   + Q  A                 L P P        QK P+
Sbjct: 514 CPPLQPHPGLHHQSSPPHPHHQPWA----------------QLHPSPQNTP----QKVPV 553

Query: 205 STENSHED--ESPMKNVSSSKGSPAPLGVRS-------KSGPLKPAREDSEN----KDHA 251
              +  E   E P+ +++   G  A L V+S       +  P +  ++   N    +D +
Sbjct: 554 HQHSPSEPFLEKPVPDMTQVSGPNAQL-VKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPS 612

Query: 252 GEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPA 311
                  FPG V     +R    L  + EEKK+ ++  A K+  + K  +E+     P  
Sbjct: 613 KGFGKDDFPGGVDNQELNRNS--LDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEP-- 668

Query: 312 RFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKF 371
           + PKAP            + KEK  K +ATPK K               N+ P+ + +  
Sbjct: 669 KTPKAPKI--------PKEPKEKKAK-TATPKPKS---------SKKSSNKKPDSEASAL 710

Query: 372 HKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLK 431
            K  +   T   + S    + PP PP      P +     S+        +  +   DL+
Sbjct: 711 KKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKRRSSR------QVKRKRYTEDLE 764

Query: 432 SPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEAS--------KEREKKREKEEKKRL 483
             ++++  D    +D AG       S+ E  E ++A           R  K++KE  + +
Sbjct: 765 FKISDEEAD---DADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQKESGEEV 821

Query: 484 ELEK-----------------KEQKEKEKKEQEIKKKFK 505
           E+E+                  E  EK+K+ Q+  K+FK
Sbjct: 822 EIEEFYVKYKNFSYLHCQWASIEDLEKDKRIQQKIKRFK 860



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 124/600 (20%), Positives = 212/600 (35%), Gaps = 88/600 (14%)

Query: 161 TSENEQKQAFPKLTGVKGKFMSASQDL-EPKPLFPKPAFGQ--------KPPLSTENSHE 211
           T+     Q+ P+     G   ++ Q L   +P+ P  +  Q          P  T  S  
Sbjct: 335 TNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPP 394

Query: 212 DESPMKNVSSSKGSPAPLGVRSKSG-PLKPAREDSENKDHAGEISSLPFPGVVLKPAASR 270
             SPMK +S+  G+P P      +G P++            G   ++P P    +P  + 
Sbjct: 395 PMSPMKAMSNPAGTPPPQVRPGSAGIPME-----------VGSYPNMPHPQPSHQPPGAM 443

Query: 271 GGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARF--PKAPSKLTVGGPWGQ 328
           G  G    G    +  +     ++   ++      +G P      P+A  +  + G    
Sbjct: 444 G-IGQRNMGPRNMQQSRPFIGMSSAPRELTGHMRPNGCPGVGLGDPQAIQERLIPGQQHP 502

Query: 329 SQEKEKGDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSK---GQT 385
            Q+       +  P Q P P L     PP  P+  P   L      S  N+  K    Q 
Sbjct: 503 GQQPSFQQLPTCPPLQ-PHPGLHHQSSPP-HPHHQPWAQL----HPSPQNTPQKVPVHQH 556

Query: 386 SYSTTSLPPPPPSHPASQPPLPASHPSQPPVPSLP--PRNIKPPFDLKSPVNEDNQDGVT 443
           S S   L  P P       P      S   +PS+   P+  K        V ED   G  
Sbjct: 557 SPSEPFLEKPVPDMTQVSGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFG 616

Query: 444 HSDGAGNLDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKE-KEKKEQEIKK 502
             D  G +D ++ +       ++ S+E +KK+++ + K+   E KE KE KE KE +  K
Sbjct: 617 KDDFPGGVDNQELNRNS----LDGSQEEKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPK 672

Query: 503 KFKLTGPIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYI 562
             K+    +      A    K  K   + K   +   ++   N +GK  G          
Sbjct: 673 APKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKKKVN-KGKTEG---------- 721

Query: 563 KTTAVEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQSGSGGIFPPPPDD 622
                     S     D    PS P E+D          +D     +  S  +      +
Sbjct: 722 ----------SENSDLDKTPPPSPPPEED----------EDPGVQKRRSSRQVKRKRYTE 761

Query: 623 DIYDGIEEEDADDGSTLQVQEKSNTWSWGILKMLKGKDDRKKSIREKPKVSDSDNNEGSS 682
           D+   I +E+ADD         SNT           + ++++S+  +  V +   +  S 
Sbjct: 762 DLEFKISDEEADDADAAGRDSPSNT----------SQSEQQESVDAEGPVVEKIMSSRS- 810

Query: 683 FPAPPKQLDMGDEVYDD---VDTSDFPVSSAEMSQGTNVGKAKTEEKDLKKLKKQEKEEK 739
                KQ + G+EV  +   V   +F     + +   ++ K K  ++ +K+ K ++ + K
Sbjct: 811 ---VKKQKESGEEVEIEEFYVKYKNFSYLHCQWASIEDLEKDKRIQQKIKRFKAKQGQNK 867



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 11/70 (15%)

Query: 626  DGIEEEDADDGSTLQVQEKSNTWSWGILKMLK----GKDDRKKSIREK-------PKVSD 674
            +G EEE+  DGS  + +++    +  +   LK    G D   KSI EK        K+ D
Sbjct: 2188 EGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEKGSEEDEEEKLED 2247

Query: 675  SDNNEGSSFP 684
             D +E SS P
Sbjct: 2248 DDKSEESSQP 2257


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 57.0 bits (136), Expect = 7e-08
 Identities = 61/276 (22%), Positives = 104/276 (37%), Gaps = 48/276 (17%)

Query: 225 SPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKE 284
           SP P   R+ S P  P R  S +      +S  P P     P   R  P LS      K 
Sbjct: 607 SPPPKR-RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS-----KH 660

Query: 285 DRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQ 344
            +    +++T +++  Q        P   P+AP   +   P  +        + S +P  
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPR--PRAPQTSSSPPPVRRGASSSPQRRQSPSPST 718

Query: 345 KPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSHPASQP 404
           +P+           + +R P     K   + S  S  +  +S S +  P P    P + P
Sbjct: 719 RPIR----------RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768

Query: 405 -PLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYE 463
            P+ +  PS    P++P +  K P    SP    +Q+G                      
Sbjct: 769 SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG---------------------- 806

Query: 464 DIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQE 499
                K+++KK++K+ KK    +KK +K K+ K+++
Sbjct: 807 ---GGKKKKKKKDKKHKK----DKKHKKHKKHKKEK 835



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 64/309 (20%), Positives = 113/309 (36%), Gaps = 40/309 (12%)

Query: 194 PKPAFGQKPPLSTENSHEDESPMKNVSSSKGSPAPLGVRSKSGPLKP-----AREDS-EN 247
           P P     P           SP     S   SPAP   + +  P  P      +E S + 
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP--EKKEKTPELPEPSVKVKEPSVQE 237

Query: 248 KDHAGEISSLPFPGVVLKPAASRGGPGLSKNGEEKKEDRKIDAAKNTFQSKINQEELASG 307
                +I  +P P  + +P      P   KN +++KE  K    ++  +SK ++    S 
Sbjct: 238 ATSTSDILKVPKPEPIPEPKE----PSPEKNSKKEKEKEKT-RPRSRSRSK-SRSRTRSR 291

Query: 308 TPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLG---PPPPKPNRPP 364
           +P    P+   +         S+ +    +   +P+++P P   T     PPPP+  R  
Sbjct: 292 SPSHTRPRRRHR---------SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342

Query: 365 NVDLTKFHKTSSGNSTSKGQTSYSTTSLPPPPPSH------------PASQPPLPASHPS 412
           +    +   ++S + +S   +S  + S P  PP              P++ PP     PS
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402

Query: 413 QPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGETYEDIEASKERE 472
            P  P  PP+    P   +S     ++  V+    +G + + + +E            + 
Sbjct: 403 PPATP--PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460

Query: 473 KKREKEEKK 481
           +  E EE K
Sbjct: 461 ELSESEEDK 469



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 94/472 (19%), Positives = 149/472 (31%), Gaps = 61/472 (12%)

Query: 46  SPPAGPSNVPKFGS-PKPPVAVK-PSSEE-----------KPD-----KEPKPPFLKPTG 87
           SP   P    K    P+P V VK PS +E           KP+     KEP P       
Sbjct: 209 SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKE 268

Query: 88  AGQRFGTPASLTTRDPEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHD 147
             +    P S +     ++     P   +P    +  S+    + P  +PS         
Sbjct: 269 KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS---YSPRRRPSPRRRPSPRR 325

Query: 148 LKPLGPKSGPTPPT---SENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPL 204
             P  P+  P PP    S +  ++       + G   S+S      P    P     PP 
Sbjct: 326 RTP--PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR 383

Query: 205 STEN----------SHEDESPMKNVSSSKGSPAPLG---VRSKSGPLKPAREDSENKDHA 251
            T             H    P      ++ SP P      R     + P R   +   H 
Sbjct: 384 KTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHK 443

Query: 252 G-----EISSLPFPGVV--LKPAASRGGPGLSKNGEEKKED---RKIDAAKNTFQSKINQ 301
           G       S  P P  V   +    +GG   + +  +++     +   ++ ++  S  ++
Sbjct: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503

Query: 302 EE------LASGTPPARFPKAPSKLTVGGPWGQSQEKEKGDKNSATPKQKPLPPLFTLGP 355
           +E      + +G    R   +PS+     P  + +E     +   +P   P     +  P
Sbjct: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563

Query: 356 -PPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTT-----SLPPPPPSHPASQPPLPAS 409
            PPP+  R P     +   +      S     YS       S  PPP    AS PP P  
Sbjct: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623

Query: 410 HPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGNLDEEQDSEGET 461
             S  P P     +  PP    SPV +     ++     G+       E  +
Sbjct: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 17/63 (26%), Positives = 35/63 (55%), Gaps = 4/63 (6%)

Query: 451 LDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEK----KEQKEKEKKEQEIKKKFKL 506
           L  +++  G     +E  KE  K+R+ E++K   ++K    K++++KE+KE   +K+ + 
Sbjct: 110 LSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERS 169

Query: 507 TGP 509
             P
Sbjct: 170 RSP 172


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.129    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,368,864
Number of Sequences: 37866
Number of extensions: 3009526
Number of successful extensions: 47639
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 793
Number of HSP's successfully gapped in prelim test: 1643
Number of HSP's that attempted gapping in prelim test: 18371
Number of HSP's gapped (non-prelim): 17670
length of query: 829
length of database: 18,247,518
effective HSP length: 111
effective length of query: 718
effective length of database: 14,044,392
effective search space: 10083873456
effective search space used: 10083873456
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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