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Search of human proteins with 41393583
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens]
(273 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens] 584 e-167
gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens] 584 e-167
gi|13449287 NG3 protein [Homo sapiens] 160 1e-39
gi|13124888 epidermal growth factor-like protein 6 precursor [Ho... 98 7e-21
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 97 1e-20
gi|75709198 nephronectin [Homo sapiens] 89 5e-18
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 77 2e-14
gi|189491647 fibulin 7 isoform 2 [Homo sapiens] 75 8e-14
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 72 5e-13
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 72 7e-13
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 72 7e-13
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 72 7e-13
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 72 7e-13
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 72 7e-13
gi|55770876 notch4 preproprotein [Homo sapiens] 70 2e-12
gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo sa... 69 3e-12
gi|110347437 latent transforming growth factor beta binding prot... 69 4e-12
gi|110347412 latent transforming growth factor beta binding prot... 69 4e-12
gi|110347431 latent transforming growth factor beta binding prot... 69 4e-12
gi|148886654 polydom [Homo sapiens] 64 1e-10
gi|148833508 notch1 preproprotein [Homo sapiens] 64 2e-10
gi|88758613 CD93 antigen precursor [Homo sapiens] 63 2e-10
gi|134244285 Notch homolog 3 [Homo sapiens] 62 4e-10
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 62 5e-10
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 61 9e-10
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 61 9e-10
gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens] 61 1e-09
gi|66346695 fibrillin 2 precursor [Homo sapiens] 60 2e-09
gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens] 60 2e-09
gi|4557679 jagged 1 precursor [Homo sapiens] 60 3e-09
>gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 584 bits (1505), Expect = e-167
Identities = 273/273 (100%), Positives = 273/273 (100%)
Query: 1 MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR 60
MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR
Sbjct: 1 MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR 60
Query: 61 ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP 120
ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP
Sbjct: 61 ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP 120
Query: 121 GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG 180
GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG
Sbjct: 121 GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG 180
Query: 181 GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL
Sbjct: 181 GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
Query: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS
Sbjct: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
>gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 584 bits (1505), Expect = e-167
Identities = 273/273 (100%), Positives = 273/273 (100%)
Query: 1 MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR 60
MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR
Sbjct: 1 MRGSQEVLLMWLLVLAVGGTEHAYRPGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHR 60
Query: 61 ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP 120
ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP
Sbjct: 61 ACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP 120
Query: 121 GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG 180
GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG
Sbjct: 121 GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG 180
Query: 181 GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL
Sbjct: 181 GPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
Query: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS
Sbjct: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
>gi|13449287 NG3 protein [Homo sapiens]
Length = 293
Score = 160 bits (405), Expect = 1e-39
Identities = 97/273 (35%), Positives = 139/273 (50%), Gaps = 17/273 (6%)
Query: 12 LLVLAVGGTEHAYRPGRRVCAVRAHGDPV--SESFVQRVYQPFLTTCDGHRACSTYRTIY 69
LL+ G + R + VC+ + P+ +ES+ Q VY+P+LT C G R CSTYRT+Y
Sbjct: 19 LLIPGEGAKGGSLRESQGVCSKQTLVVPLHYNESYSQPVYKPYLTLCAGRRICSTYRTMY 78
Query: 70 RTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGA-AICQPPCRNGGSCVQPGRCRCPAG 128
R +R + CC GWK+ PGA AIC PC NGG CV+P +C C G
Sbjct: 79 RVMWREVRREVQ-QTHAVCCQGWKKRH--PGALTCEAICAKPCLNGGVCVRPDQCECAPG 135
Query: 129 WRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPN 188
W G C DVDEC C C NTAGS+ C C L DG C+ P + +
Sbjct: 136 WGGKHCHVDVDECRTSITLCSHHCFNTAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSAS 195
Query: 189 PTGV--------DSAMKEEVQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGLPDPGSLL 240
V + A+K+E+ L+ R++ LE+ A + ++ E P+ +
Sbjct: 196 ILSVAVREAEKDERALKQEIHELRGRLERLEQWAGQAGAWVRAVLPVPPEELQPEQ---V 252
Query: 241 VHSFQQLGRIDSLSEQISFLEEQLGSCSCKKDS 273
+ + RI+SLS+Q+ LEE+LG+CSC+ +S
Sbjct: 253 AELWGRGDRIESLSDQVLLLEERLGACSCEDNS 285
>gi|13124888 epidermal growth factor-like protein 6 precursor [Homo
sapiens]
Length = 553
Score = 98.2 bits (243), Expect = 7e-21
Identities = 50/106 (47%), Positives = 59/106 (55%), Gaps = 5/106 (4%)
Query: 72 AYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRG 131
A R PG+ + ACC GW+R S G C A C+P C+ G CV P +CRC G+ G
Sbjct: 33 ASARQPGVCHYGTKLACCYGWRRNS--KGVCEAT-CEPGCKFG-ECVGPNKCRCFPGYTG 88
Query: 132 DTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
TC DV+EC + C RCVNT GSY C C GH L D T CV
Sbjct: 89 KTCSQDVNECGMKPRPCQHRCVNTHGSYKCFCLSGHMLMPDAT-CV 133
Score = 45.8 bits (107), Expect = 4e-05
Identities = 28/75 (37%), Positives = 37/75 (49%), Gaps = 11/75 (14%)
Query: 102 CGAAICQPPCRNGGSCVQPGRCRCPAGW-----RGDTCQSDVDECSARRGGCP--QRCVN 154
C CQ C + Q C CP+ G C D+DEC++ + CP +RCVN
Sbjct: 138 CAMINCQYSCEDTEEGPQ---CLCPSSGLRLAPNGRDCL-DIDECASGKVICPYNRRCVN 193
Query: 155 TAGSYWCQCWEGHSL 169
T GSY+C+C G L
Sbjct: 194 TFGSYYCKCHIGFEL 208
Score = 35.4 bits (80), Expect = 0.054
Identities = 22/101 (21%), Positives = 46/101 (45%), Gaps = 11/101 (10%)
Query: 123 CRCPAGWR-----GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGHSLSADGTL 175
C+C G+ G D++EC+ C C NT GS+ C+C +G+ +
Sbjct: 200 CKCHIGFELQYISGRYDCIDINECTMDSHTCSHHANCFNTQGSFKCKCKQGYKGNGLRCS 259
Query: 176 CVPKGGPPRVAPNPTGVDSAMKEEVQRLQSRVDLLEEKLQL 216
+P+ V P +K+ +++L + + +++K ++
Sbjct: 260 AIPENSVKEVLRAP----GTIKDRIKKLLAHKNSMKKKAKI 296
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 97.4 bits (241), Expect = 1e-20
Identities = 51/125 (40%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 56 CDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGG 115
C GH + Y YR Y AR CC GW + G A C +GG
Sbjct: 83 CVGHERRTVYYMGYRQVYTTE-----ARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGG 137
Query: 116 SCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSAD 172
CV PG C CP G++G CQ DVDEC GGC RCVNT GSY C+C G L D
Sbjct: 138 RCV-PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTD 196
Query: 173 GTLCV 177
C+
Sbjct: 197 SRTCL 201
Score = 62.0 bits (149), Expect = 5e-10
Identities = 45/134 (33%), Positives = 62/134 (46%), Gaps = 20/134 (14%)
Query: 107 CQPPCRNGGSCVQPG--RCRCPAGWR--GDTCQ-SDVDECSARRGGCPQRCVNTAGSYWC 161
CQ C N PG C C AG+R D C DVDEC++ RGGC C N AGS+ C
Sbjct: 382 CQQVCTNN-----PGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQC 436
Query: 162 QCWEGHSLSADGTLCVPKGGP--------PRVAPNPTGVDSAMKEEVQRLQSRVDLLEEK 213
C G+ L D C P P P V P P + +++E+ +L D+ ++
Sbjct: 437 SCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPH--IAVLQDELPQLFQDDDVGADE 494
Query: 214 LQLVLAPLHSLASQ 227
+ L H+L +
Sbjct: 495 EEAELRGEHTLTEK 508
Score = 60.1 bits (144), Expect = 2e-09
Identities = 39/110 (35%), Positives = 51/110 (46%), Gaps = 17/110 (15%)
Query: 79 LAPARPRYACCPGWKRTSGLPGACGAAICQPPCRN-GGSCVQP-------GRCRCPAGWR 130
L R R C PG++ L + + PC N GSC+ RC C G++
Sbjct: 220 LTITRHRCQCRPGFQ----LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQ 275
Query: 131 ----GDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
G C+ DVDEC+A C C+NT GS+ C C G+ L ADG C
Sbjct: 276 LAADGKACE-DVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQC 324
Score = 51.2 bits (121), Expect = 9e-07
Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 17/112 (15%)
Query: 81 PARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCV-------QPGRCRCPAGWRGDT 133
P AC GW + C + CR+ G C+ GRC CPAGW GD
Sbjct: 1056 PVSGHCACPEGWAGLA-CEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDK 1114
Query: 134 CQSD-----VDECSARRGGCP--QRCVNTAGSYWCQCWEGHSLSADGTLCVP 178
CQS E A+R CP C + G+ C+C G + S C P
Sbjct: 1115 CQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPP 1164
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/77 (38%), Positives = 34/77 (44%), Gaps = 13/77 (16%)
Query: 81 PARPRYACCPGWKRTSGLPGACGAAICQPPCR------NGGSCVQ-PGRCRCPAGWRGDT 133
P + C PGW S L AC A + CR NGG+C G C CP GW G
Sbjct: 1013 PVHGQCHCAPGWMGPSCLQ-ACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLA 1071
Query: 134 CQSDVDECSAR--RGGC 148
C+ EC R R GC
Sbjct: 1072 CEK---ECLPRDVRAGC 1085
Score = 42.7 bits (99), Expect = 3e-04
Identities = 45/133 (33%), Positives = 52/133 (39%), Gaps = 24/133 (18%)
Query: 77 PGLAPARPRYAC-CPGWKRTSGLPGACG--------AAICQPPCRNGGSCVQPGRCRCPA 127
PG A AC CP SG AC A +CQ P N G C C A
Sbjct: 1136 PGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAA 1195
Query: 128 GWRGDTCQSDVDECSARR--GGCPQ--RCVN----TAGSYWCQCWEGHSLSADGTLCVPK 179
G+ G +CQ C R GC Q C+N A + C+C G L D L P+
Sbjct: 1196 GYHGPSCQ---QRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGF-LGTDCNLTCPQ 1251
Query: 180 GGPPRVAPNPTGV 192
G R PN T V
Sbjct: 1252 G---RFGPNCTHV 1261
Score = 42.0 bits (97), Expect = 6e-04
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 11/85 (12%)
Query: 101 ACGAAICQPPCRNGGSCVQPGRCRCPAGWR----GDTC----QSDVDECSARRGGCPQRC 152
A G A C C N +C C AG+ G C V+ C A GGC C
Sbjct: 290 AAGLAQCAHGCLNTQGSF---KCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGC 346
Query: 153 VNTAGSYWCQCWEGHSLSADGTLCV 177
+T+ C C G+ L D C+
Sbjct: 347 SHTSAGPLCTCPRGYELDTDQRTCI 371
Score = 40.8 bits (94), Expect = 0.001
Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 10/80 (12%)
Query: 74 RRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQ-PGRCRCPAGWRGD 132
R PG + C PG+ +G G C C++G C GRC CPAG+ G
Sbjct: 1364 RCGPGFYGQACEHPCPPGF-HGAGCQGLCW-------CQHGAPCDPISGRCLCPAGFHGH 1415
Query: 133 TCQSDVDECSARRGGCPQRC 152
C+ + S GC QRC
Sbjct: 1416 FCERGCEPGSFGE-GCHQRC 1434
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/84 (36%), Positives = 38/84 (45%), Gaps = 23/84 (27%)
Query: 111 CRNGGSCVQP-GRCRCPAGWRG----DTCQSDV------DECSARRGGCPQRCVNTAGSY 159
CRNGG+C+ C CP GW G +TC D CS + GG C + G+
Sbjct: 527 CRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGG---TCDSVTGA- 582
Query: 160 WCQCWEGHSLSADGTLC---VPKG 180
C+C G S GT C PKG
Sbjct: 583 -CRCPPGVS----GTNCEDGCPKG 601
Score = 39.3 bits (90), Expect = 0.004
Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 24/109 (22%)
Query: 77 PGLAPARPRYACCPGWKRTSGLPGACGAAICQP--PCRNGGSC-VQPGRCRCPAGWRGDT 133
PG +R + C GW S CQ C N G C G C C GW G +
Sbjct: 806 PGFVGSRCQDVCPAGWYGPS----------CQTRCSCANDGHCHPATGHCSCAPGWTGFS 855
Query: 134 CQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH-SLSADGTLCVPKGG 181
CQ D G C S+ C C GH S A LC+ + G
Sbjct: 856 CQRACD-----TGHWGPDC-----SHPCNCSAGHGSCDAISGLCLCEAG 894
Score = 38.9 bits (89), Expect = 0.005
Identities = 27/70 (38%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 107 CQPPCRNGGSCVQ-PGRCRCPAGWRGDTCQSDVDECSARRGG--CPQRCVNTAGSYWCQC 163
CQ C++G +C G C CPAGWRG C+ C A G C C TAG+ C
Sbjct: 917 CQ--CQHGAACDHVSGACTCPAGWRGTFCE---HACPAGFFGLDCRSACNCTAGAA-CDA 970
Query: 164 WEGHSLSADG 173
G L G
Sbjct: 971 VNGSCLCPAG 980
Score = 37.7 bits (86), Expect = 0.011
Identities = 32/123 (26%), Positives = 41/123 (33%), Gaps = 40/123 (32%)
Query: 109 PPCRNGGSCVQP---------GRCRCPAGWRGDTCQSDVD------------------EC 141
P C CVQP G C C AG+RG+ CQ++ + C
Sbjct: 648 PGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVAC 707
Query: 142 SARRGGCPQRCVN-----------TAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPT 190
+ G C +RC G++ C S S G C G R P T
Sbjct: 708 DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNC--SSSCSCGGAPCHGVTGQCRCPPGRT 765
Query: 191 GVD 193
G D
Sbjct: 766 GED 768
Score = 37.0 bits (84), Expect = 0.018
Identities = 32/109 (29%), Positives = 36/109 (33%), Gaps = 20/109 (18%)
Query: 81 PARPRYACCPGWKRTSGLPGACGAAI----CQPPCR---NGGSC-VQPGRCRCPAGWRGD 132
PA +C PGW S AC C PC GSC G C C AG+ G
Sbjct: 840 PATGHCSCAPGWTGFS-CQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGP 898
Query: 133 TCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLS-ADGTLCVPKG 180
C+ CPQ CQC G + G P G
Sbjct: 899 RCEQQ----------CPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG 937
Score = 37.0 bits (84), Expect = 0.018
Identities = 30/122 (24%), Positives = 35/122 (28%), Gaps = 41/122 (33%)
Query: 89 CPGWKRTSGLPGACGAAICQPPCRNGGSC-VQPGRCRCPAGWRGDTCQSDVDE------- 140
CP + G CG C NGGSC G CRCP G+ G C +
Sbjct: 1206 CPPGRYGPGCEQLCG-------CLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNC 1258
Query: 141 ---CSARRG-----------------------GCPQRCVNTAGSYWCQCWEGHSLSADGT 174
C +G GCPQ + C C G A
Sbjct: 1259 THVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG 1318
Query: 175 LC 176
C
Sbjct: 1319 SC 1320
Score = 37.0 bits (84), Expect = 0.018
Identities = 34/104 (32%), Positives = 42/104 (40%), Gaps = 22/104 (21%)
Query: 99 PGACGAAICQPPCRNGGSCVQP--GRCRCPAGWRGDTCQSDVDECSARRG----GCPQRC 152
PG+ G Q +GG+ P G C CP G G TC D RRG C C
Sbjct: 1423 PGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLD-----CRRGQFGPSCTLHC 1477
Query: 153 VNTAG------SYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPT 190
G S C C +G+ G C +GGP R+ NP+
Sbjct: 1478 DCGGGADCDPVSGQCHCVDGYM----GPTC-REGGPLRLPENPS 1516
Score = 36.6 bits (83), Expect = 0.024
Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 31/115 (26%)
Query: 107 CQPPCRNGGSCVQ--PGRCRCPAGWRGDTCQSDVDE-------------------CSARR 145
C C GG+ G+CRCP G G+ C++D E C
Sbjct: 740 CSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPET 799
Query: 146 GGC-------PQRC--VNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTG 191
G C RC V AG Y C S + DG C P G AP TG
Sbjct: 800 GACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGH-CHPATGHCSCAPGWTG 853
Score = 36.6 bits (83), Expect = 0.024
Identities = 32/111 (28%), Positives = 36/111 (32%), Gaps = 25/111 (22%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQP-------GRCRCPAGWRGDTCQSDVDE 140
C GW+ T AC A CR+ +C G C CPAG RG C
Sbjct: 934 CPAGWRGTF-CEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET--- 989
Query: 141 CSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTG 191
CP S C C+ G S C P G AP G
Sbjct: 990 -------CPAHTYGHNCSQACACFNGAS-------CDPVHGQCHCAPGWMG 1026
Score = 34.7 bits (78), Expect = 0.092
Identities = 28/96 (29%), Positives = 37/96 (38%), Gaps = 34/96 (35%)
Query: 111 CRNGGSCVQ-PGRCRCPAGWRGDTCQSDV----------DECS-ARRGGCPQ---RCVNT 155
C+NGG+C G CRCP G G C+ +C+ A RG C + C+
Sbjct: 570 CQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCD 629
Query: 156 AGSY----------W---------CQCWEGHSLSAD 172
G Y W CQC + H+ S D
Sbjct: 630 PGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCD 665
Score = 34.7 bits (78), Expect = 0.092
Identities = 23/78 (29%), Positives = 26/78 (33%), Gaps = 18/78 (23%)
Query: 111 CRNGGSC-VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSL 169
CRNGG C G C C GW G C+ CP A C C
Sbjct: 1307 CRNGGLCHASNGSCSCGLGWTGRHCEL----------ACPPGRYGAACHLECSC------ 1350
Query: 170 SADGTLCVPKGGPPRVAP 187
+ + C P G R P
Sbjct: 1351 -HNNSTCEPATGTCRCGP 1367
Score = 31.2 bits (69), Expect = 1.0
Identities = 21/66 (31%), Positives = 25/66 (37%), Gaps = 10/66 (15%)
Query: 99 PGACGAAI-CQPPCRNGGSCVQP-GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTA 156
PG GAA + C N +C G CRC G+ G C+ GC C
Sbjct: 1337 PGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPP-GFHGAGCQGLC---- 1391
Query: 157 GSYWCQ 162
WCQ
Sbjct: 1392 ---WCQ 1394
>gi|75709198 nephronectin [Homo sapiens]
Length = 565
Score = 88.6 bits (218), Expect = 5e-18
Identities = 42/99 (42%), Positives = 55/99 (55%), Gaps = 4/99 (4%)
Query: 76 SPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQ 135
S GL R CC GW R S G C +CQP C++G C+ P +C+C G+ G TC
Sbjct: 32 SIGLCRYGGRIDCCWGWARQSW--GQC-QPVCQPRCKHG-ECIGPNKCKCHPGYAGKTCN 87
Query: 136 SDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGT 174
D++EC + C RC+NT GSY C C G+ L DG+
Sbjct: 88 QDLNECGLKPRPCKHRCMNTYGSYKCYCLNGYMLMPDGS 126
Score = 51.2 bits (121), Expect = 9e-07
Identities = 32/80 (40%), Positives = 44/80 (55%), Gaps = 11/80 (13%)
Query: 100 GACGAAIC--QPPCRNGGSCVQPG-RCRCPAGWR-----GDTCQSDVDECSARRGGCPQ- 150
G+C +A+ C+ G V+ RC+CP+ G TC DVDEC+ R CP+
Sbjct: 125 GSCSSALTCSMANCQYGCDVVKGQIRCQCPSPGLQLAPDGRTCV-DVDECATGRASCPRF 183
Query: 151 -RCVNTAGSYWCQCWEGHSL 169
+CVNT GSY C+C +G L
Sbjct: 184 RQCVNTFGSYICKCHKGFDL 203
Score = 41.6 bits (96), Expect = 8e-04
Identities = 28/76 (36%), Positives = 36/76 (47%), Gaps = 12/76 (15%)
Query: 123 CRCPAGWR-----GDTCQSDVDECSARRGGCPQ--RCVNTAGSYWCQCWEGHSLSADGTL 175
C+C G+ G D+DECS + C RC N GSY C+C EG+ DG
Sbjct: 195 CKCHKGFDLMYIGGKYQCHDIDECSLGQYQCSSFARCYNIRGSYKCKCKEGY--QGDGLT 252
Query: 176 CVPKGGPPRVAPNPTG 191
CV P+V P+G
Sbjct: 253 CV---YIPKVMIEPSG 265
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 76.6 bits (187), Expect = 2e-14
Identities = 38/96 (39%), Positives = 50/96 (52%), Gaps = 9/96 (9%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CR GG+CV P +C CP+G+ G C+ D+DEC+ R
Sbjct: 504 CKPGYVGN----GTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHT 559
Query: 148 C--PQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGG 181
C C+N AG + C C G S S D C +GG
Sbjct: 560 CWNDSACINLAGGFDCLCPSGPSCSGD---CPHEGG 592
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 9/68 (13%)
Query: 109 PPCRNGGSCVQ---PGRCRCPAGW---RGDTCQ-SDVDECSARRGGCPQR--CVNTAGSY 159
P C C C C +G+ +GD+ D+DEC+A+ C CVN G Y
Sbjct: 399 PKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLY 458
Query: 160 WCQCWEGH 167
C C G+
Sbjct: 459 RCDCVPGY 466
>gi|189491647 fibulin 7 isoform 2 [Homo sapiens]
Length = 393
Score = 74.7 bits (182), Expect = 8e-14
Identities = 49/137 (35%), Positives = 61/137 (44%), Gaps = 14/137 (10%)
Query: 54 TTCDGHRACSTYRTIYRTAYRRSPGLAPARPR-YACCPGWKRTSGLPGACGAAICQP-PC 111
T DG + S Y + + +PG P C P T P G + C PC
Sbjct: 86 TPADGRKFGSKYLVDHEVHFTCNPGFRLVGPSSVVCLPNGTWTGEQPHCRGISECSSQPC 145
Query: 112 RNGGSCVQ---PGRCRCPAGWRGDTCQ----SDVDECS-----ARRGGCPQRCVNTAGSY 159
+NGG+CV+ RC CP G G+ CQ +DV+EC R C CVNT GSY
Sbjct: 146 QNGGTCVEGVNQYRCICPPGRTGNRCQHQAQTDVNECELYGQEGRPRLCMHACVNTPGSY 205
Query: 160 WCQCWEGHSLSADGTLC 176
C C G+ ADG C
Sbjct: 206 RCTCPGGYRTLADGKSC 222
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 72.0 bits (175), Expect = 5e-13
Identities = 37/96 (38%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CR GG+CV P +C CP+G+ G C+ D+DECS
Sbjct: 504 CKPGYVGN----GTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIE 559
Query: 148 C--PQRCVNTAGSYWCQCWEGH----SLSADGTLCV 177
C RCVN G Y C+C G + S G C+
Sbjct: 560 CHNHSRCVNLPGWYHCECRSGFHDDGTYSLSGESCI 595
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 9/68 (13%)
Query: 109 PPCRNGGSCVQ---PGRCRCPAGW---RGDTCQ-SDVDECSARRGGCPQR--CVNTAGSY 159
P C C C C +G+ +GD+ D+DEC+A+ C CVN G Y
Sbjct: 399 PKCGENSECKNWNTKATCECKSGYISVQGDSAYCEDIDECAAKMHYCHANTVCVNLPGLY 458
Query: 160 WCQCWEGH 167
C C G+
Sbjct: 459 RCDCVPGY 466
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CRNGG+C+ C CP G+ G +C++D+DECS
Sbjct: 533 CKPGYTGN----GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQ 588
Query: 148 CPQR--CVNTAGSYWCQCWEGH 167
C R C+N G Y C+C +G+
Sbjct: 589 CDSRANCINLPGWYHCECRDGY 610
Score = 36.6 bits (83), Expect = 0.024
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 123 CRCPAGWRG----DTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGH 167
C C G+R + D+DEC+ R C + CVNT GS+ C C G+
Sbjct: 445 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 495
Score = 35.8 bits (81), Expect = 0.041
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 111 CRNGGSCVQ-PGR--CRCPAGWR--GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
CR CV PG C C G+ D ++ DEC + C + C NT G + C C
Sbjct: 474 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 533
Query: 164 WEGHSLSADGTLC 176
G+ + +GT C
Sbjct: 534 KPGY--TGNGTTC 544
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CRNGG+C+ C CP G+ G +C++D+DECS
Sbjct: 509 CKPGYTGN----GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQ 564
Query: 148 CPQR--CVNTAGSYWCQCWEGH 167
C R C+N G Y C+C +G+
Sbjct: 565 CDSRANCINLPGWYHCECRDGY 586
Score = 36.6 bits (83), Expect = 0.024
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 123 CRCPAGWRG----DTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGH 167
C C G+R + D+DEC+ R C + CVNT GS+ C C G+
Sbjct: 421 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 471
Score = 35.8 bits (81), Expect = 0.041
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 111 CRNGGSCVQ-PGR--CRCPAGWR--GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
CR CV PG C C G+ D ++ DEC + C + C NT G + C C
Sbjct: 450 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 509
Query: 164 WEGHSLSADGTLC 176
G+ + +GT C
Sbjct: 510 KPGY--TGNGTTC 520
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CRNGG+C+ C CP G+ G +C++D+DECS
Sbjct: 510 CKPGYTGN----GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQ 565
Query: 148 CPQR--CVNTAGSYWCQCWEGH 167
C R C+N G Y C+C +G+
Sbjct: 566 CDSRANCINLPGWYHCECRDGY 587
Score = 36.6 bits (83), Expect = 0.024
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 123 CRCPAGWRG----DTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGH 167
C C G+R + D+DEC+ R C + CVNT GS+ C C G+
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Score = 35.8 bits (81), Expect = 0.041
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 111 CRNGGSCVQ-PGR--CRCPAGWR--GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
CR CV PG C C G+ D ++ DEC + C + C NT G + C C
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
Query: 164 WEGHSLSADGTLC 176
G+ + +GT C
Sbjct: 511 KPGY--TGNGTTC 521
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CRNGG+C+ C CP G+ G +C++D+DECS
Sbjct: 560 CKPGYTGN----GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQ 615
Query: 148 CPQR--CVNTAGSYWCQCWEGH 167
C R C+N G Y C+C +G+
Sbjct: 616 CDSRANCINLPGWYHCECRDGY 637
Score = 36.6 bits (83), Expect = 0.024
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 123 CRCPAGWRG----DTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGH 167
C C G+R + D+DEC+ R C + CVNT GS+ C C G+
Sbjct: 472 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 522
Score = 35.8 bits (81), Expect = 0.041
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 111 CRNGGSCVQ-PGR--CRCPAGWR--GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
CR CV PG C C G+ D ++ DEC + C + C NT G + C C
Sbjct: 501 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 560
Query: 164 WEGHSLSADGTLC 176
G+ + +GT C
Sbjct: 561 KPGY--TGNGTTC 571
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 71.6 bits (174), Expect = 7e-13
Identities = 32/82 (39%), Positives = 45/82 (54%), Gaps = 6/82 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG 147
C PG+ G A C+ CRNGG+C+ C CP G+ G +C++D+DECS
Sbjct: 510 CKPGYTGN----GTTCKAFCKDGCRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQ 565
Query: 148 CPQR--CVNTAGSYWCQCWEGH 167
C R C+N G Y C+C +G+
Sbjct: 566 CDSRANCINLPGWYHCECRDGY 587
Score = 36.6 bits (83), Expect = 0.024
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 6/51 (11%)
Query: 123 CRCPAGWRG----DTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGH 167
C C G+R + D+DEC+ R C + CVNT GS+ C C G+
Sbjct: 422 CSCRDGFRALREDNAYCEDIDECAEGRHYCRENTMCVNTPGSFMCICKTGY 472
Score = 35.8 bits (81), Expect = 0.041
Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 111 CRNGGSCVQ-PGR--CRCPAGWR--GDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
CR CV PG C C G+ D ++ DEC + C + C NT G + C C
Sbjct: 451 CRENTMCVNTPGSFMCICKTGYIRIDDYSCTEHDECITNQHNCDENALCFNTVGGHNCVC 510
Query: 164 WEGHSLSADGTLC 176
G+ + +GT C
Sbjct: 511 KPGY--TGNGTTC 521
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 70.1 bits (170), Expect = 2e-12
Identities = 44/117 (37%), Positives = 55/117 (47%), Gaps = 16/117 (13%)
Query: 80 APARPRYACCPGWK-RTSGLPGACGAAICQPPCRNGGSCVQPG---RCRCPAGWRGDTCQ 135
A RP+ +C PGW L C A PC NGG C+ +C CP G+ G C+
Sbjct: 137 ASGRPQCSCMPGWTGEQCQLRDFCSAN----PCVNGGVCLATYPQIQCHCPPGFEGHACE 192
Query: 136 SDVDECSARRGGCPQ--RCVNTAGSYWCQCWEGHSLSADGTLCVPKGG--PPRVAPN 188
DV+EC G CP+ C NT GS+ C C G +G C + G PPR N
Sbjct: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ----EGPRCELRAGPCPPRGCSN 245
Score = 54.3 bits (129), Expect = 1e-07
Identities = 25/71 (35%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 109 PPCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWE 165
P CRNGG+C C C +GW G +C+ ++D+C A C++ GS+ C C
Sbjct: 324 PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPP 383
Query: 166 GHSLSADGTLC 176
G + G LC
Sbjct: 384 GRT----GLLC 390
Score = 54.3 bits (129), Expect = 1e-07
Identities = 31/82 (37%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 110 PCRNGGSCV-QPG--RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC NGG C QPG C+C G+ G CQ++VDEC + C++ G+++C C G
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
Query: 167 HSLSADGTLC-VPKGGPPRVAP 187
+ G LC VP P P
Sbjct: 619 FT----GQLCEVPLCAPNLCQP 636
Score = 53.5 bits (127), Expect = 2e-07
Identities = 36/96 (37%), Positives = 43/96 (44%), Gaps = 21/96 (21%)
Query: 111 CRNGGSCVQPG----RCRCPAGWRGDTCQSDVDECS------ARRGGCPQRCVNTAGSYW 160
C+NGG+C Q G C CP W G C DVDEC R GG C N+AGS+
Sbjct: 285 CQNGGTC-QDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGG---TCQNSAGSFH 340
Query: 161 CQC---WEGHSLSADGTLCVPKGGPPRVAPNPTGVD 193
C C W G S + C+ AP T +D
Sbjct: 341 CVCVSGWGGTSCEENLDDCI----AATCAPGSTCID 372
Score = 51.6 bits (122), Expect = 7e-07
Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 111 CRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
C NGG CV G C CP G++G CQ V+ C +R C+ Y CQC G+
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 168 SLSADGTLC 176
DG C
Sbjct: 961 ----DGQNC 965
Score = 51.2 bits (121), Expect = 9e-07
Identities = 31/89 (34%), Positives = 44/89 (49%), Gaps = 13/89 (14%)
Query: 88 CCPGWKRTSGLPGACGAAI--CQP-PCRNGGSCV-QPG--RCRCPAGWRGDTCQSDVDEC 141
C PG+ + C + CQ PC N G+C +PG C CP G+ G C+ DVDEC
Sbjct: 956 CAPGYDGQN-----CSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC 1010
Query: 142 SAR--RGGCPQRCVNTAGSYWCQCWEGHS 168
+ C + A +++CQC GH+
Sbjct: 1011 LDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
Score = 50.1 bits (118), Expect = 2e-06
Identities = 27/72 (37%), Positives = 39/72 (54%), Gaps = 11/72 (15%)
Query: 110 PCRNGGSCV---QPGRCRCPAGWRGDTCQSDVDECSARRGGCPQ--RCVNTAGSYWCQCW 164
PCRN +C Q RC CP G+ G +CQ+ +D C+ + CP+ C+ T S+ C C
Sbjct: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK--PCPRNSHCLQTGPSFHCLCL 871
Query: 165 EGHSLSADGTLC 176
+G + G LC
Sbjct: 872 QGWT----GPLC 879
Score = 48.5 bits (114), Expect = 6e-06
Identities = 24/70 (34%), Positives = 37/70 (52%), Gaps = 7/70 (10%)
Query: 110 PCRNGGSCVQ-PG--RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC +GGSC+ PG C CP G+ G C++D +EC ++ C++ ++ C C G
Sbjct: 445 PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG 504
Query: 167 HSLSADGTLC 176
+G LC
Sbjct: 505 ----LEGQLC 510
Score = 45.1 bits (105), Expect = 7e-05
Identities = 35/128 (27%), Positives = 43/128 (33%), Gaps = 25/128 (19%)
Query: 80 APARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG---RCRCPAGWRGDTCQS 136
+P PR C G+ T G Q PC C+Q G C C GW G C
Sbjct: 824 SPQGPRCLCPTGY--TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
Query: 137 DVDECS-------------ARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPP 183
+ C GG CV++ SY+C C G G+LC P
Sbjct: 882 PLSSCQKAALSQGIDVSSLCHNGGL---CVDSGPSYFCHCPPGF----QGSLCQDHVNPC 934
Query: 184 RVAPNPTG 191
P G
Sbjct: 935 ESRPCQNG 942
Score = 44.7 bits (104), Expect = 9e-05
Identities = 24/60 (40%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 110 PCRNGGSC-VQPGR--CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC NGGSC PG C CP G CQ+ D C + CVN G++ C C G
Sbjct: 737 PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
Score = 44.3 bits (103), Expect = 1e-04
Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 13/81 (16%)
Query: 110 PCRNGGSC-----VQPGRCRCPAGWRGDTCQSDVDEC-SARRGGCP----QRCVNTAGSY 159
PC C C C G+ G TC D+DEC A++G P C+NT GS+
Sbjct: 400 PCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSF 459
Query: 160 WCQC---WEGHSLSADGTLCV 177
C C + G AD C+
Sbjct: 460 NCLCPPGYTGSRCEADHNECL 480
Score = 43.9 bits (102), Expect = 2e-04
Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 11/90 (12%)
Query: 104 AAICQPP-CRNGGSC-VQPGR------CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNT 155
A C P C NGG+C + P + C CP G+ G C+ + D C + + C +
Sbjct: 235 AGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDG 294
Query: 156 AGSYWCQC---WEGHSLSADGTLCVPKGGP 182
+Y C C W G S D C +G P
Sbjct: 295 LDTYTCLCPETWTGWDCSEDVDECETQGPP 324
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 21/95 (22%)
Query: 84 PRYAC-CPGWKRTSGLPGACGAAICQP--------PCRNGGSCV-QPGR--CRCPAGWRG 131
P Y C CP PG G+ +CQ PC+NG +C+ QP C+C G+ G
Sbjct: 912 PSYFCHCP--------PGFQGS-LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG 962
Query: 132 DTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
C ++D C ++ C G + C C G
Sbjct: 963 QNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPG 997
Score = 41.2 bits (95), Expect = 0.001
Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC N C + +C C G+ G C+ D+DEC + +C + G++ C+C G
Sbjct: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPG 580
Score = 37.0 bits (84), Expect = 0.018
Identities = 20/70 (28%), Positives = 29/70 (41%), Gaps = 7/70 (10%)
Query: 110 PCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC G +C+ C CP G G C+ + +EC++ C + + C C G
Sbjct: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
Query: 167 HSLSADGTLC 176
S GT C
Sbjct: 543 FS----GTRC 548
Score = 36.2 bits (82), Expect = 0.032
Identities = 14/30 (46%), Positives = 19/30 (63%), Gaps = 4/30 (13%)
Query: 110 PCRNGGSCVQ----PGRCRCPAGWRGDTCQ 135
PC NGG+C+ G C+C G+ G+TCQ
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
Score = 35.8 bits (81), Expect = 0.041
Identities = 23/81 (28%), Positives = 32/81 (39%), Gaps = 8/81 (9%)
Query: 103 GAAICQPPCRN----GGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGS 158
G+ C PP N G C Q C C GW G C++++ C + C
Sbjct: 654 GSPGCAPPEDNCTCHHGHC-QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG 712
Query: 159 YWCQC---WEGHSLSADGTLC 176
Y C C + G + S + T C
Sbjct: 713 YNCTCPTGYTGPTCSEEMTAC 733
Score = 34.7 bits (78), Expect = 0.092
Identities = 25/84 (29%), Positives = 29/84 (34%), Gaps = 10/84 (11%)
Query: 110 PCRNGGSCVQPGR------CRCPAGWRGDTCQSDVDECS---ARRGGCPQRCVNTAGSYW 160
PC +GG+C C CP G+ G TC C GG
Sbjct: 1054 PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPR 1113
Query: 161 CQCWEGHSLSADGTLCVPKG-GPP 183
C C G+ T PKG GPP
Sbjct: 1114 CACLSGYGGPDCLTPPAPKGCGPP 1137
Score = 33.9 bits (76), Expect = 0.16
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 23/123 (18%)
Query: 87 ACCPGWK--RTSGLPGACGAAICQPPCRNG-GSCVQPGRCRCPAGWRGDTCQSDVDECSA 143
AC PG+ R G C C P S C+C G G C+ ++D C +
Sbjct: 993 ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 144 RRGGCPQRCVNTAGS---YWCQC---WEGHSLS-----------ADGTLCVPK---GGPP 183
+ C TAGS + C C +EG + S G LC+P G PP
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPP 1112
Query: 184 RVA 186
R A
Sbjct: 1113 RCA 1115
Score = 32.7 bits (73), Expect = 0.35
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 31/103 (30%)
Query: 88 CCPGWK-RTSGLPGACGAAICQPPCRNGGSC----------------VQPG-RCRCPAGW 129
C PG+ T P C A C+NGGSC + P C C G+
Sbjct: 53 CAPGFLGETCQFPDPCQNAQL---CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGF 109
Query: 130 RGDTCQSDVDE------CSARRGGCPQRCVNTAGSYWCQCWEG 166
G+ CQ+ +++ CS +RG C + +G C C G
Sbjct: 110 TGERCQAKLEDPCPPSFCS-KRGRCH---IQASGRPQCSCMPG 148
>gi|4557617 growth arrest-specific 6 isoform 1 precursor [Homo
sapiens]
Length = 678
Score = 69.3 bits (168), Expect = 3e-12
Identities = 51/154 (33%), Positives = 59/154 (38%), Gaps = 28/154 (18%)
Query: 46 QRVYQPFLTTCDGH-------RACSTYRTIYRTAYRRSPGLAPARPRYACCPG-----WK 93
+R +Q F GH CS R R + P PRY C +
Sbjct: 47 RRAFQVFEEAKQGHLERECVEELCS--REEAREVFENDPETDYFYPRYLDCINKYGSPYT 104
Query: 94 RTSG-------LPGACGAAICQPPCRNGGSCVQPGR----CRCPAGWRGDTCQSDVDECS 142
+ SG LP C C R G Q C C AGW G C DV+ECS
Sbjct: 105 KNSGFATCVQNLPDQCTPNPCD---RKGTQACQDLMGNFFCLCKAGWGGRLCDKDVNECS 161
Query: 143 ARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
GGC Q C N GS+ C C G LS+DG C
Sbjct: 162 QENGGCLQICHNKPGSFHCSCHSGFELSSDGRTC 195
Score = 39.7 bits (91), Expect = 0.003
Identities = 31/83 (37%), Positives = 37/83 (44%), Gaps = 18/83 (21%)
Query: 101 ACGAAICQPPCRNGGSCVQPGR--CRCPAGWRGDTCQS---DVDECSARRGGCPQRCVNT 155
ACG A C+ PG C C G+ + + DVDEC +G C Q CVN+
Sbjct: 206 ACGEARCKN---------LPGSYSCLCDEGFAYSSQEKACRDVDECL--QGRCEQVCVNS 254
Query: 156 AGSYWCQC--WEGHSLSADGTLC 176
GSY C C G LS D C
Sbjct: 255 PGSYTCHCDGRGGLKLSQDMDTC 277
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 68.9 bits (167), Expect = 4e-12
Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 82 ARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQSDVD 139
A P A C + PG CG C+ PG RC CPAG+RG C+ DVD
Sbjct: 595 AAPHGASCQDVDECTQSPGLCGRGACKN---------LPGSFRCVCPAGFRGSACEEDVD 645
Query: 140 ECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADGTLC 176
EC+ C P RC NTAGS+ C C G G C
Sbjct: 646 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 683
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/106 (33%), Positives = 43/106 (40%), Gaps = 17/106 (16%)
Query: 85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRC---------RCPAGWR----G 131
R +C PG++ SG PG C C G C G C C G+R G
Sbjct: 792 RCSCAPGYRAPSGRPGPCADV---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 848
Query: 132 DTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+C DVDECS C NT GS+ C C GH D C+
Sbjct: 849 ASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 893
Score = 47.4 bits (111), Expect = 1e-05
Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 86 YACCPGWKRTSGLPGACG----AAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQS--- 136
+ CP R+ G C A PPC G G +C CP G++ +T S
Sbjct: 667 HCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 726
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQ-CWEGHSL 169
DVDEC Q CVN+ GS+ C+ C GH L
Sbjct: 727 DVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 760
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 77 PGLAPARPR-YAC-CPGWKRTSGLPGAC-GAAICQ---PPCRNGGSCVQPG--RCRCPAG 128
PG +RP Y C C R S C C+ PPC G PG RC C G
Sbjct: 491 PGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPG 550
Query: 129 WRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLC 176
+R + DVDEC C RC NT GS+ C C G+ + G C
Sbjct: 551 FRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC 602
Score = 42.4 bits (98), Expect = 4e-04
Identities = 20/47 (42%), Positives = 23/47 (48%), Gaps = 7/47 (14%)
Query: 96 SGLPGACG-------AAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQ 135
SG PG A +C C NGG CV+P RC CP + G CQ
Sbjct: 68 SGAPGGAAPGGPGFRAFLCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 114
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/134 (29%), Positives = 50/134 (37%), Gaps = 12/134 (8%)
Query: 64 TYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQ--PPCRNGGSCV-QP 120
T+R R R P P P P W + +CQ P G C+ +P
Sbjct: 440 THRLEPRPEPRPDPRPGPELP-LPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRP 498
Query: 121 G--RCRCPAGWR----GDTCQSDVDECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADG 173
C C +G+R G C DVDEC C P RC N+ GS+ C C G
Sbjct: 499 SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRA 557
Query: 174 TLCVPKGGPPRVAP 187
C+ RV P
Sbjct: 558 AECLDVDECHRVPP 571
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 14/105 (13%)
Query: 77 PGLAPARPRYACCPGWKRTSGLP-GACGAAICQPPCRNGGSCVQPGRCRCPAGWR--GDT 133
PGL R + CC G +GL G +C N P CP G+ +
Sbjct: 236 PGL---RTQEVCCRG----AGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNGS 287
Query: 134 CQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
C+ DVDEC A G C C NT G Y C C +G L + + C+
Sbjct: 288 CE-DVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 19/128 (14%)
Query: 58 GHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSC 117
G + C YR PG A P C + P CGA C+
Sbjct: 907 GSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGAQRCENT------- 958
Query: 118 VQPGRCRC-PA---GWR---GDTCQSDVDECSARRG-GCPQRCVNTAGSYWCQCWEGHSL 169
PG RC PA G++ G CQ DVDEC R G C N GS+ C C +G+
Sbjct: 959 --PGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1015
Query: 170 SADGTLCV 177
+ DG CV
Sbjct: 1016 ARDGRHCV 1023
Score = 38.1 bits (87), Expect = 0.008
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 111 CRNGGSCVQPGR---CRCPAGWRGDTCQS---DVDECSARRGGCP----QRCVNTAGSYW 160
C NG CV+ CRC G+R D + D++EC P RC+NT GS+
Sbjct: 1476 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1534
Query: 161 CQCWEGHSLSADGTLCVP 178
C C G + + C P
Sbjct: 1535 CICRPGFAPTHQPHHCAP 1552
Score = 37.0 bits (84), Expect = 0.018
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 24/89 (26%)
Query: 114 GGSCVQ-PG--RCR-CPAGW---RGDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCW 164
G CV PG +CR CP+G RG +DVDECS+ C C NT GS+ C C
Sbjct: 739 GQECVNSPGSFQCRTCPSGHHLHRGRC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 796
Query: 165 EGHSLSA-------------DGTLCVPKG 180
G+ + +G C P G
Sbjct: 797 PGYRAPSGRPGPCADVNECLEGDFCFPHG 825
Score = 36.2 bits (82), Expect = 0.032
Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 115 GSCVQ--PG-RCRCPAGWRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGH 167
G CV PG C C G+ T + D DEC+ C RCVNT GSY C C
Sbjct: 1201 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1260
Query: 168 SLSADGTLCV 177
L CV
Sbjct: 1261 VLDGSQRRCV 1270
Score = 30.4 bits (67), Expect = 1.7
Identities = 12/41 (29%), Positives = 19/41 (46%)
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+ +EC G RCV + C+C++G+ L CV
Sbjct: 1466 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1506
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 68.9 bits (167), Expect = 4e-12
Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 82 ARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQSDVD 139
A P A C + PG CG C+ PG RC CPAG+RG C+ DVD
Sbjct: 625 AAPHGASCQDVDECTQSPGLCGRGACKN---------LPGSFRCVCPAGFRGSACEEDVD 675
Query: 140 ECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADGTLC 176
EC+ C P RC NTAGS+ C C G G C
Sbjct: 676 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 713
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/106 (33%), Positives = 43/106 (40%), Gaps = 17/106 (16%)
Query: 85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRC---------RCPAGWR----G 131
R +C PG++ SG PG C C G C G C C G+R G
Sbjct: 822 RCSCAPGYRAPSGRPGPCADV---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 878
Query: 132 DTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+C DVDECS C NT GS+ C C GH D C+
Sbjct: 879 ASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 923
Score = 47.4 bits (111), Expect = 1e-05
Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 86 YACCPGWKRTSGLPGACG----AAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQS--- 136
+ CP R+ G C A PPC G G +C CP G++ +T S
Sbjct: 697 HCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 756
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQ-CWEGHSL 169
DVDEC Q CVN+ GS+ C+ C GH L
Sbjct: 757 DVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 790
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 77 PGLAPARPR-YAC-CPGWKRTSGLPGAC-GAAICQ---PPCRNGGSCVQPG--RCRCPAG 128
PG +RP Y C C R S C C+ PPC G PG RC C G
Sbjct: 521 PGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPG 580
Query: 129 WRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLC 176
+R + DVDEC C RC NT GS+ C C G+ + G C
Sbjct: 581 FRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC 632
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/134 (29%), Positives = 50/134 (37%), Gaps = 12/134 (8%)
Query: 64 TYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQ--PPCRNGGSCV-QP 120
T+R R R P P P P W + +CQ P G C+ +P
Sbjct: 470 THRLEPRPEPRPDPRPGPELP-LPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRP 528
Query: 121 G--RCRCPAGWR----GDTCQSDVDECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADG 173
C C +G+R G C DVDEC C P RC N+ GS+ C C G
Sbjct: 529 SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRA 587
Query: 174 TLCVPKGGPPRVAP 187
C+ RV P
Sbjct: 588 AECLDVDECHRVPP 601
Score = 41.2 bits (95), Expect = 0.001
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 99 PGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQ 135
P +C C NGG CV+P RC CP + G CQ
Sbjct: 108 PAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 144
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 14/105 (13%)
Query: 77 PGLAPARPRYACCPGWKRTSGLP-GACGAAICQPPCRNGGSCVQPGRCRCPAGWR--GDT 133
PGL R + CC G +GL G +C N P CP G+ +
Sbjct: 266 PGL---RTQEVCCRG----AGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNGS 317
Query: 134 CQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
C+ DVDEC A G C C NT G Y C C +G L + + C+
Sbjct: 318 CE-DVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 19/128 (14%)
Query: 58 GHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSC 117
G + C YR PG A P C + P CGA C+
Sbjct: 937 GSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGAQRCENT------- 988
Query: 118 VQPGRCRC-PA---GWR---GDTCQSDVDECSARRG-GCPQRCVNTAGSYWCQCWEGHSL 169
PG RC PA G++ G CQ DVDEC R G C N GS+ C C +G+
Sbjct: 989 --PGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1045
Query: 170 SADGTLCV 177
+ DG CV
Sbjct: 1046 ARDGRHCV 1053
Score = 38.1 bits (87), Expect = 0.008
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 111 CRNGGSCVQPGR---CRCPAGWRGDTCQS---DVDECSARRGGCP----QRCVNTAGSYW 160
C NG CV+ CRC G+R D + D++EC P RC+NT GS+
Sbjct: 1506 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1564
Query: 161 CQCWEGHSLSADGTLCVP 178
C C G + + C P
Sbjct: 1565 CICRPGFAPTHQPHHCAP 1582
Score = 37.0 bits (84), Expect = 0.018
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 24/89 (26%)
Query: 114 GGSCVQ-PG--RCR-CPAGW---RGDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCW 164
G CV PG +CR CP+G RG +DVDECS+ C C NT GS+ C C
Sbjct: 769 GQECVNSPGSFQCRTCPSGHHLHRGRC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 826
Query: 165 EGHSLSA-------------DGTLCVPKG 180
G+ + +G C P G
Sbjct: 827 PGYRAPSGRPGPCADVNECLEGDFCFPHG 855
Score = 36.2 bits (82), Expect = 0.032
Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 115 GSCVQ--PG-RCRCPAGWRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGH 167
G CV PG C C G+ T + D DEC+ C RCVNT GSY C C
Sbjct: 1231 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1290
Query: 168 SLSADGTLCV 177
L CV
Sbjct: 1291 VLDGSQRRCV 1300
Score = 30.4 bits (67), Expect = 1.7
Identities = 12/41 (29%), Positives = 19/41 (46%)
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+ +EC G RCV + C+C++G+ L CV
Sbjct: 1496 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1536
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 68.9 bits (167), Expect = 4e-12
Identities = 39/98 (39%), Positives = 45/98 (45%), Gaps = 12/98 (12%)
Query: 82 ARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQSDVD 139
A P A C + PG CG C+ PG RC CPAG+RG C+ DVD
Sbjct: 662 AAPHGASCQDVDECTQSPGLCGRGACKN---------LPGSFRCVCPAGFRGSACEEDVD 712
Query: 140 ECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADGTLC 176
EC+ C P RC NTAGS+ C C G G C
Sbjct: 713 ECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPC 750
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/106 (33%), Positives = 43/106 (40%), Gaps = 17/106 (16%)
Query: 85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRC---------RCPAGWR----G 131
R +C PG++ SG PG C C G C G C C G+R G
Sbjct: 859 RCSCAPGYRAPSGRPGPCADV---NECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRG 915
Query: 132 DTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+C DVDECS C NT GS+ C C GH D C+
Sbjct: 916 ASCL-DVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL 960
Score = 47.4 bits (111), Expect = 1e-05
Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 86 YACCPGWKRTSGLPGACG----AAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQS--- 136
+ CP R+ G C A PPC G G +C CP G++ +T S
Sbjct: 734 HCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE 793
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQ-CWEGHSL 169
DVDEC Q CVN+ GS+ C+ C GH L
Sbjct: 794 DVDECENHLACPGQECVNSPGSFQCRTCPSGHHL 827
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/112 (34%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 77 PGLAPARPR-YAC-CPGWKRTSGLPGAC-GAAICQ---PPCRNGGSCVQPG--RCRCPAG 128
PG +RP Y C C R S C C+ PPC G PG RC C G
Sbjct: 558 PGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCENSPGSFRCVCGPG 617
Query: 129 WRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLC 176
+R + DVDEC C RC NT GS+ C C G+ + G C
Sbjct: 618 FRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGYQAAPHGASC 669
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/134 (29%), Positives = 50/134 (37%), Gaps = 12/134 (8%)
Query: 64 TYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQ--PPCRNGGSCV-QP 120
T+R R R P P P P W + +CQ P G C+ +P
Sbjct: 507 THRLEPRPEPRPDPRPGPELP-LPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRP 565
Query: 121 G--RCRCPAGWR----GDTCQSDVDECSARRGGC-PQRCVNTAGSYWCQCWEGHSLSADG 173
C C +G+R G C DVDEC C P RC N+ GS+ C C G
Sbjct: 566 SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGRCENSPGSFRCVCGPGFRAGPRA 624
Query: 174 TLCVPKGGPPRVAP 187
C+ RV P
Sbjct: 625 AECLDVDECHRVPP 638
Score = 41.2 bits (95), Expect = 0.001
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 99 PGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQ 135
P +C C NGG CV+P RC CP + G CQ
Sbjct: 145 PAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFCQ 181
Score = 41.2 bits (95), Expect = 0.001
Identities = 35/105 (33%), Positives = 45/105 (42%), Gaps = 14/105 (13%)
Query: 77 PGLAPARPRYACCPGWKRTSGLP-GACGAAICQPPCRNGGSCVQPGRCRCPAGWR--GDT 133
PGL R + CC G +GL G +C N P CP G+ +
Sbjct: 303 PGL---RTQEVCCRG----AGLAWGVHDCQLCSERLGNSERVSAPDG-PCPTGFERVNGS 354
Query: 134 CQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
C+ DVDEC A G C C NT G Y C C +G L + + C+
Sbjct: 355 CE-DVDEC-ATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 41.2 bits (95), Expect = 0.001
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 19/128 (14%)
Query: 58 GHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSC 117
G + C YR PG A P C + P CGA C+
Sbjct: 974 GSQRCENSPGSYRCVRDCDPGYH-AGPEGTCDDVDECQEYGPEICGAQRCENT------- 1025
Query: 118 VQPGRCRC-PA---GWR---GDTCQSDVDECSARRG-GCPQRCVNTAGSYWCQCWEGHSL 169
PG RC PA G++ G CQ DVDEC R G C N GS+ C C +G+
Sbjct: 1026 --PGSYRCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEG 1082
Query: 170 SADGTLCV 177
+ DG CV
Sbjct: 1083 ARDGRHCV 1090
Score = 38.1 bits (87), Expect = 0.008
Identities = 26/78 (33%), Positives = 35/78 (44%), Gaps = 11/78 (14%)
Query: 111 CRNGGSCVQPGR---CRCPAGWRGDTCQS---DVDECSARRGGCP----QRCVNTAGSYW 160
C NG CV+ CRC G+R D + D++EC P RC+NT GS+
Sbjct: 1543 CTNG-RCVRVPEGFTCRCFDGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFR 1601
Query: 161 CQCWEGHSLSADGTLCVP 178
C C G + + C P
Sbjct: 1602 CICRPGFAPTHQPHHCAP 1619
Score = 37.0 bits (84), Expect = 0.018
Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 24/89 (26%)
Query: 114 GGSCVQ-PG--RCR-CPAGW---RGDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCW 164
G CV PG +CR CP+G RG +DVDECS+ C C NT GS+ C C
Sbjct: 806 GQECVNSPGSFQCRTCPSGHHLHRGRC--TDVDECSSGAPPCGPHGHCTNTEGSFRCSCA 863
Query: 165 EGHSLSA-------------DGTLCVPKG 180
G+ + +G C P G
Sbjct: 864 PGYRAPSGRPGPCADVNECLEGDFCFPHG 892
Score = 36.2 bits (82), Expect = 0.032
Identities = 27/70 (38%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 115 GSCVQ--PG-RCRCPAGWRGDTCQS---DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGH 167
G CV PG C C G+ T + D DEC+ C RCVNT GSY C C
Sbjct: 1268 GVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYHCTCEPPL 1327
Query: 168 SLSADGTLCV 177
L CV
Sbjct: 1328 VLDGSQRRCV 1337
Score = 30.4 bits (67), Expect = 1.7
Identities = 12/41 (29%), Positives = 19/41 (46%)
Query: 137 DVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCV 177
+ +EC G RCV + C+C++G+ L CV
Sbjct: 1533 EAEECGILDGCTNGRCVRVPEGFTCRCFDGYRLDMTRMACV 1573
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 63.9 bits (154), Expect = 1e-10
Identities = 33/89 (37%), Positives = 40/89 (44%), Gaps = 9/89 (10%)
Query: 83 RPRYACCP-GWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDEC 141
RP CP GW + C IC PC NGG CV P +C CP GW G C + V +
Sbjct: 3484 RPNACSCPEGW-----MGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQS 3538
Query: 142 SARRGGCPQRCVNTAGSYWCQCWEGHSLS 170
GG +CV + W GH+ S
Sbjct: 3539 PCLNGG---KCVRPNRCHCLSSWTGHNCS 3564
Score = 55.1 bits (131), Expect = 7e-08
Identities = 26/65 (40%), Positives = 32/65 (49%), Gaps = 9/65 (13%)
Query: 105 AICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC- 163
A+C+ PC+NGG C +P C CP GW G C+ + GG RCV Y C C
Sbjct: 3470 AVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGG---RCV---APYQCDCP 3523
Query: 164 --WEG 166
W G
Sbjct: 3524 PGWTG 3528
Score = 53.1 bits (126), Expect = 2e-07
Identities = 24/62 (38%), Positives = 34/62 (54%), Gaps = 3/62 (4%)
Query: 110 PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC N G+C Q GR C CP G+ G C++D+DECS C + G + C+C G
Sbjct: 1201 PCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSG 1260
Query: 167 HS 168
++
Sbjct: 1261 YT 1262
Score = 50.8 bits (120), Expect = 1e-06
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 88 CCPGWKRTSGLPGACGAAICQ---PPCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDEC 141
C PG+ T CG + + PC+NG +C RC C AG+ G C+ +++EC
Sbjct: 1333 CPPGFLGTR-----CGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINEC 1387
Query: 142 SARRGGCPQRCVNTAGSYWCQCWEGHS 168
+ CV+ SY C+C G S
Sbjct: 1388 QSNPCRNQATCVDELNSYSCKCQPGFS 1414
Score = 46.6 bits (109), Expect = 2e-05
Identities = 23/64 (35%), Positives = 32/64 (50%), Gaps = 4/64 (6%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C P PC N G C V C CP+G+ G C+ +++ECS+ CV+ Y C
Sbjct: 1235 CSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCT 1294
Query: 163 CWEG 166
C +G
Sbjct: 1295 CVKG 1298
Score = 40.8 bits (94), Expect = 0.001
Identities = 23/64 (35%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
CQ PC N C V C+CP G+ G C +VDEC ++ C + A S+ C
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCL 1370
Query: 163 CWEG 166
C G
Sbjct: 1371 CAAG 1374
Score = 38.9 bits (89), Expect = 0.005
Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 110 PCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC N G CV RC C G+ G C+++V+EC + C + G + C+C G
Sbjct: 1277 PCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPG 1336
Score = 30.8 bits (68), Expect = 1.3
Identities = 23/71 (32%), Positives = 30/71 (42%), Gaps = 8/71 (11%)
Query: 111 CRNGGSCVQPGRCRCP--AGWRGDTCQS-DVDECSARRGGCPQR--CVNTAGSYWCQCWE 165
C NG + R C W G + DVDEC+ C + C+N GSY C C
Sbjct: 1716 CNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVG-SDCSEHASCLNVDGSYICSCVP 1774
Query: 166 GHSLSADGTLC 176
+ + DG C
Sbjct: 1775 PY--TGDGKNC 1783
Score = 28.9 bits (63), Expect = 5.0
Identities = 13/35 (37%), Positives = 19/35 (54%), Gaps = 4/35 (11%)
Query: 107 CQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSD 137
CQ PCRN +CV C+C G+ G C+++
Sbjct: 1387 CQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 63.5 bits (153), Expect = 2e-10
Identities = 31/70 (44%), Positives = 36/70 (51%), Gaps = 6/70 (8%)
Query: 105 AICQP-PCRNGGSCVQPG-----RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGS 158
A C P PCRNGG C Q C CP GW+G TC+ D++EC C NT G
Sbjct: 831 APCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGG 890
Query: 159 YWCQCWEGHS 168
Y C C G+S
Sbjct: 891 YRCHCQAGYS 900
Score = 61.6 bits (148), Expect = 7e-10
Identities = 33/90 (36%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 86 YACCPGWKRTSGLPGACGAAICQPPCRNGGSC-VQPGR----CRCPAGWRGDTCQSDVDE 140
Y CP + +GL A PC G +C P C CP+G+ G C DVDE
Sbjct: 358 YCECPHGR--TGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDE 415
Query: 141 CSARRGGCPQ--RCVNTAGSYWCQCWEGHS 168
CS C +C+NT GS+ CQC +G++
Sbjct: 416 CSLGANPCEHAGKCINTLGSFECQCLQGYT 445
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/171 (30%), Positives = 62/171 (36%), Gaps = 34/171 (19%)
Query: 31 CAVRAHGDPVSESFVQRVYQPFLTTCDG--HRACSTYRTIYRTAYRRSPGLAPARPRYAC 88
C HG + + +P L G H +YR + R + G RP C
Sbjct: 166 CPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHT---GPNCERPYVPC 222
Query: 89 CP------GWKRTSG--------LPGA----CGAAICQPP---CRNGGSCVQ---PGRCR 124
P G R +G LPG C I P C+NGG+CV CR
Sbjct: 223 SPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCR 282
Query: 125 CPAGWRGDTCQSDVDECSARRGGCPQ--RCVNTAGSYWCQC---WEGHSLS 170
CP W G C DVDEC C C NT G Y C C W G S
Sbjct: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCS 333
Score = 58.2 bits (139), Expect = 8e-09
Identities = 32/86 (37%), Positives = 38/86 (44%), Gaps = 8/86 (9%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSAR 144
C PGW SG PC NGG C+ C CP + G TC+ DV+EC +
Sbjct: 129 CPPGW---SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQK 185
Query: 145 RGGCPQ--RCVNTAGSYWCQCWEGHS 168
G C C N GSY C C H+
Sbjct: 186 PGLCRHGGTCHNEVGSYRCVCRATHT 211
Score = 53.5 bits (127), Expect = 2e-07
Identities = 30/93 (32%), Positives = 45/93 (48%), Gaps = 11/93 (11%)
Query: 88 CCPGWKRTSGLPGACGAAIC-QPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSA 143
C PG++ G+ C PC + G C + +C CP G+ G CQ DVDEC++
Sbjct: 478 CMPGYE---GVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS 534
Query: 144 RRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
+C++ +Y C C EG++ GT C
Sbjct: 535 TPCKNGAKCLDGPNTYTCVCTEGYT----GTHC 563
Score = 52.4 bits (124), Expect = 4e-07
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 8/79 (10%)
Query: 110 PCRNGGSC----VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC-- 163
PCRNGG+C + +CRCP GW G +CQ D C++ +C+ SY C C
Sbjct: 110 PCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ-QADPCASNPCANGGQCLPFEASYICHCPP 168
Query: 164 -WEGHSLSADGTLCVPKGG 181
+ G + D C K G
Sbjct: 169 SFHGPTCRQDVNECGQKPG 187
Score = 52.4 bits (124), Expect = 4e-07
Identities = 25/66 (37%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C+P PC NGGSC + C C G+RG C+ D++EC++ C + SY C
Sbjct: 911 CRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCT 970
Query: 163 CWEGHS 168
C G S
Sbjct: 971 CPAGFS 976
Score = 52.4 bits (124), Expect = 4e-07
Identities = 35/100 (35%), Positives = 46/100 (46%), Gaps = 21/100 (21%)
Query: 86 YAC-CPGWKRTSGLPGACGAAICQPP---------CRNGGSCV-QPG--RCRCPAGWRGD 132
Y C CP + T G+ C PP C N G+CV Q G C CP G+ G+
Sbjct: 1205 YKCSCP--RGTQGVHCEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGE 1262
Query: 133 TCQSDVDECSAR----RGGCPQRCVNTAGSYWCQCWEGHS 168
C+ DV+EC + RG Q CV + C+C GH+
Sbjct: 1263 RCEGDVNECLSNPCDARG--TQNCVQRVNDFHCECRAGHT 1300
Score = 51.2 bits (121), Expect = 9e-07
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 111 CRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
C++GG CV G CRC AG+ G C+ VDECS C + G Y C+C G+
Sbjct: 1116 CQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGY 1175
Score = 50.1 bits (118), Expect = 2e-06
Identities = 24/61 (39%), Positives = 33/61 (54%), Gaps = 3/61 (4%)
Query: 111 CRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
C NGG+CV C CP G+ G CQ DV+EC ++ C + GSY C C +G+
Sbjct: 992 CFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGY 1051
Query: 168 S 168
+
Sbjct: 1052 T 1052
Score = 49.3 bits (116), Expect = 4e-06
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 9/74 (12%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQC-- 163
PC NGG+C + CRCP G+ TC S+V+EC++ C C ++ Y C C
Sbjct: 686 PCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNS--NPCVHGACRDSLNGYKCDCDP 743
Query: 164 -WEGHSLSADGTLC 176
W G + + C
Sbjct: 744 GWSGTNCDINNNEC 757
Score = 48.1 bits (113), Expect = 8e-06
Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 13/73 (17%)
Query: 110 PCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDEC---SARRGGCPQRCVNTAGSYWCQC 163
PCR+G SC RC C AG+ G C++D+D+C GG +NTA +C C
Sbjct: 877 PCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTA---FCDC 933
Query: 164 WEGHSLSADGTLC 176
G GT C
Sbjct: 934 LPGFR----GTFC 942
Score = 47.4 bits (111), Expect = 1e-05
Identities = 24/92 (26%), Positives = 38/92 (41%), Gaps = 7/92 (7%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSAR 144
C P W + C+NGG+C C C GW G+ C ++D+C++
Sbjct: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
Query: 145 RGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
C + S++C+C G + G LC
Sbjct: 343 ACFHGATCHDRVASFYCECPHGRT----GLLC 370
Score = 46.6 bits (109), Expect = 2e-05
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 11/118 (9%)
Query: 88 CCPGWKRTSGLPGACGAAICQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSA 143
C PGW SG C+ PC NGG+C C C G+ G CQ++++EC++
Sbjct: 741 CDPGW---SGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECAS 797
Query: 144 RRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEEVQ 201
C++ Y C C L G C P +P G + E+ +
Sbjct: 798 NPCLNQGTCIDDVAGYKCNC----LLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYE 851
Score = 46.6 bits (109), Expect = 2e-05
Identities = 21/60 (35%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 110 PCRNGGSCVQPGR------CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC 163
PC+NGG+C C+CPAG+ G TC++D C + R C++ S C C
Sbjct: 1315 PCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLC 1374
Score = 46.2 bits (108), Expect = 3e-05
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 15/93 (16%)
Query: 110 PCRNGGSCVQPG----RCRCPAGWRGDTCQSDVDECSA---RRGGCPQRCVNTAGSYWCQ 162
PC +GG+C Q G RC CP G+ G CQ+ V C + + GG +C T Y C+
Sbjct: 1029 PCLHGGTC-QDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGG---KCWQTHTQYRCE 1084
Query: 163 CWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSA 195
C G + G C VA GVD A
Sbjct: 1085 CPSGWT----GLYCDVPSVSCEVAAQRQGVDVA 1113
Score = 46.2 bits (108), Expect = 3e-05
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 4/64 (6%)
Query: 107 CQP-PCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C P PC+NG +C C+C AG+ G C ++DEC + C++ +Y C
Sbjct: 1149 CSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCS 1208
Query: 163 CWEG 166
C G
Sbjct: 1209 CPRG 1212
Score = 45.1 bits (105), Expect = 7e-05
Identities = 27/85 (31%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 88 CCPGWKRTSGLPGACGAAI---CQPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDEC 141
C PG++ T C I PCRNG +C V C CPAG+ G C+++ +C
Sbjct: 933 CLPGFRGTF-----CEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDC 987
Query: 142 SARRGGCPQRCVNTAGSYWCQCWEG 166
+ CV+ S+ C C G
Sbjct: 988 TESSCFNGGTCVDGINSFTCLCPPG 1012
Score = 43.1 bits (100), Expect = 3e-04
Identities = 18/61 (29%), Positives = 29/61 (47%), Gaps = 3/61 (4%)
Query: 110 PCRNGGSCVQP---GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC + G C+ C+C G+ G C+ DV+EC + C++ G + C C G
Sbjct: 422 PCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPG 481
Query: 167 H 167
+
Sbjct: 482 Y 482
Score = 39.7 bits (91), Expect = 0.003
Identities = 22/70 (31%), Positives = 36/70 (51%), Gaps = 7/70 (10%)
Query: 110 PCRNGGSCV-QPG--RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC+N +C+ Q G +C C G+ G C+ + DEC++ RC++ + C+C G
Sbjct: 460 PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTG 519
Query: 167 HSLSADGTLC 176
+ G LC
Sbjct: 520 FT----GHLC 525
Score = 39.7 bits (91), Expect = 0.003
Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 10/71 (14%)
Query: 110 PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWE 165
PCR+GG+C C C G G C+ ++D+C++ C C++ Y C C
Sbjct: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCAS--SPCDSGTCLDKIDGYECACEP 668
Query: 166 GHSLSADGTLC 176
G++ G++C
Sbjct: 669 GYT----GSMC 675
Score = 38.5 bits (88), Expect = 0.006
Identities = 19/63 (30%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 110 PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWE 165
PC+NG C+ C C G+ G C+ D+DEC C C + ++ C C
Sbjct: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP--DPCHYGSCKDGVATFTCLCRP 593
Query: 166 GHS 168
G++
Sbjct: 594 GYT 596
Score = 38.5 bits (88), Expect = 0.006
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 9/66 (13%)
Query: 107 CQPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSA---RRGGCPQRCVNTAGSYW 160
C P + GSC V C C G+ G C+++++ECS+ R GG C + +Y
Sbjct: 570 CDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGG---TCQDRDNAYL 626
Query: 161 CQCWEG 166
C C +G
Sbjct: 627 CFCLKG 632
Score = 38.5 bits (88), Expect = 0.006
Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 13/100 (13%)
Query: 88 CCPGW--KRTSGLPGACGAAICQPPCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECS 142
C PG+ +R G C + C R +CVQ C C AG G C+S ++ C
Sbjct: 1255 CPPGFVGERCEGDVNECLSNPCD--ARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCK 1312
Query: 143 ---ARRGGCPQRCVNTAGSYWCQC---WEGHSLSADGTLC 176
+ GG NTA + C+C +EG + D C
Sbjct: 1313 GKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTC 1352
Score = 36.6 bits (83), Expect = 0.024
Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC + G+C + C C G+ G C ++DEC+ C + + C+C EG
Sbjct: 649 PC-DSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEG 707
Query: 167 H 167
+
Sbjct: 708 Y 708
Score = 36.6 bits (83), Expect = 0.024
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 2/61 (3%)
Query: 110 PCRNGG--SCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
PC +G + +C C GW G C + +EC + C + Y C C EG
Sbjct: 724 PCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGF 783
Query: 168 S 168
S
Sbjct: 784 S 784
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 63.2 bits (152), Expect = 2e-10
Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 11/95 (11%)
Query: 88 CCPGWKRTSGLPGACGAAICQP-PCRNGGSCV-----QPGRCRCPAGWRGDTCQ---SDV 138
C PG++ L C PCR G +CV + CRCP G++ D+ Q DV
Sbjct: 287 CRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGYQLDSSQLDCVDV 346
Query: 139 DECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADG 173
DEC + C Q CVNT G + C+CW G+ G
Sbjct: 347 DEC--QDSPCAQECVNTPGGFRCECWVGYEPGGPG 379
Score = 61.2 bits (147), Expect = 9e-10
Identities = 47/121 (38%), Positives = 55/121 (45%), Gaps = 19/121 (15%)
Query: 79 LAPARPRYAC-CP-GWKRTSGLPGACGAAICQP-PCRNGGSCVQ-PG--RCRCPAGWR-- 130
L P Y C CP G++ S CQ PC CV PG RC C G+
Sbjct: 319 LGPHGKNYTCRCPQGYQLDSSQLDCVDVDECQDSPCAQ--ECVNTPGGFRCECWVGYEPG 376
Query: 131 --GDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSA-DGTL------CVPKGG 181
G+ DVDEC+ R C Q C NT GS+ C C EG+ L+ DGT CV GG
Sbjct: 377 GPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGG 436
Query: 182 P 182
P
Sbjct: 437 P 437
Score = 49.3 bits (116), Expect = 4e-06
Identities = 39/121 (32%), Positives = 48/121 (39%), Gaps = 19/121 (15%)
Query: 81 PARPRYACCPGWKRTSGLPGACG----AAICQPPCRNGGSCVQPG-RCRCPAGW-----R 130
P R C G++ GAC A+ + PC G + C C G+
Sbjct: 362 PGGFRCECWVGYEPGGPGEGACQDVDECALGRSPCAQGCTNTDGSFHCSCEEGYVLAGED 421
Query: 131 GDTCQSDVDECSARRGG-CPQRCVNTAGSYWCQCWEGHSLSADGTLCV-------PKGGP 182
G CQ DVDEC G C C NT GS+ C C G L+ +G C P GP
Sbjct: 422 GTQCQ-DVDECVGPGGPLCDSLCFNTQGSFHCGCLPGWVLAPNGVSCTMGPVSLGPPSGP 480
Query: 183 P 183
P
Sbjct: 481 P 481
Score = 32.0 bits (71), Expect = 0.59
Identities = 18/53 (33%), Positives = 21/53 (39%), Gaps = 1/53 (1%)
Query: 128 GWRGDTCQSDVDECSARRGGCPQRCVNTA-GSYWCQCWEGHSLSADGTLCVPK 179
G G C S C+ GGC Q C GS+ C C G L D C +
Sbjct: 251 GSSGPLCVSPKYGCNFNNGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASR 303
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 62.4 bits (150), Expect = 4e-10
Identities = 47/116 (40%), Positives = 61/116 (52%), Gaps = 24/116 (20%)
Query: 85 RYAC-CPGWKR--TSGLPGACGAAICQPPCRNGGSC-VQP-GR--CRCPAGWRGDTCQSD 137
R++C CP R LP C ++ PC +G C V P GR C CP G++G +C+SD
Sbjct: 103 RFSCRCPRGFRGPDCSLPDPCLSS----PCAHGARCSVGPDGRFLCSCPPGYQGRSCRSD 158
Query: 138 VDEC----SARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNP 189
VDEC R GG C+NT GS+ CQC G++ G LC P AP+P
Sbjct: 159 VDECRVGEPCRHGG---TCLNTPGSFRCQCPAGYT----GPLCENPAVP--CAPSP 205
Score = 62.0 bits (149), Expect = 5e-10
Identities = 33/74 (44%), Positives = 41/74 (55%), Gaps = 8/74 (10%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
CQ PC NGG C V C CP+G+ G TCQ DVDEC++ +CV+ Y C+
Sbjct: 473 CQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECR 532
Query: 163 CWEGHSLSADGTLC 176
C EG +GTLC
Sbjct: 533 CAEGF----EGTLC 542
Score = 61.6 bits (148), Expect = 7e-10
Identities = 31/68 (45%), Positives = 38/68 (55%), Gaps = 6/68 (8%)
Query: 107 CQP-PCRNGGSCVQ-PGR---CRCPAGWRGDTCQSDVDECSARRGGCPQR-CVNTAGSYW 160
C P PC +GG C PG+ C CP GW+G CQ DVDEC+ P C N AGS+
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFS 834
Query: 161 CQCWEGHS 168
C C G++
Sbjct: 835 CTCHGGYT 842
Score = 60.8 bits (146), Expect = 1e-09
Identities = 37/90 (41%), Positives = 42/90 (46%), Gaps = 9/90 (10%)
Query: 86 YACCPGWKRTSGLPGACGAAICQPPCRNGGSC-VQP--GR--CRCPAGWRGDTCQSDVDE 140
Y CP K +GL A PC C P GR C CP G+ G C DVDE
Sbjct: 337 YCACPMGK--TGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDE 394
Query: 141 CSARRGGCPQ--RCVNTAGSYWCQCWEGHS 168
CS C RCVNT GS+ CQC G++
Sbjct: 395 CSIGANPCEHLGRCVNTQGSFLCQCGRGYT 424
Score = 58.2 bits (139), Expect = 8e-09
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 16/95 (16%)
Query: 87 ACCPGWKRTSGLPGACGAAICQPP---CRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDE 140
AC PG++ + C + P C NGG+CV C+CP W G C DVDE
Sbjct: 223 ACLPGFEGQN-----CEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDE 277
Query: 141 CSARRGGCPQ--RCVNTAGSYWCQC---WEGHSLS 170
C + C C NT G + C C W G S S
Sbjct: 278 CQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCS 312
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/81 (38%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 104 AAICQP-PCRNGGSCVQPGR----CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGS 158
A C P PCRNGG+C Q G C C G+ G C+ +VD+C R CV+ +
Sbjct: 198 AVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNT 257
Query: 159 YWCQC---WEGHSLSADGTLC 176
Y CQC W G + D C
Sbjct: 258 YNCQCPPEWTGQFCTEDVDEC 278
Score = 53.1 bits (126), Expect = 2e-07
Identities = 36/121 (29%), Positives = 49/121 (40%), Gaps = 18/121 (14%)
Query: 86 YACCPGWKRTSGLPGACGAAICQPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECS 142
Y CP + S + QP C++GG+C + C C G+ GD C+ DVDEC+
Sbjct: 1069 YCVCPEGRTGSHCEQEVDPCLAQP-CQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECA 1127
Query: 143 ARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC----------VPKGGPPRVAPNPTGV 192
++ C++ Y C C G G LC P PR N T V
Sbjct: 1128 SQPCQHGGSCIDLVARYLCSCPPG----TLGVLCEINEDDCGPGPPLDSGPRCLHNGTCV 1183
Query: 193 D 193
D
Sbjct: 1184 D 1184
Score = 51.6 bits (122), Expect = 7e-07
Identities = 40/115 (34%), Positives = 48/115 (41%), Gaps = 29/115 (25%)
Query: 81 PARPRYACCPGWKRTS------GLPGACGAAICQPPCRNGGSCVQPG------RCRCPAG 128
P PR AC PG S PGA A+ PC +GGSC +P RC C G
Sbjct: 1308 PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSC-RPAPLAPFFRCACAQG 1366
Query: 129 WRGDTCQS-----DVDE--------CSARRGGCPQRCVNTAGSYWCQCWEGHSLS 170
W G C++ +V E C A+RG QRC S C W+G S
Sbjct: 1367 WTGPRCEAPAAAPEVSEEPRCPRAACQAKRG--DQRCDRECNSPGCG-WDGGDCS 1418
Score = 51.2 bits (121), Expect = 9e-07
Identities = 30/71 (42%), Positives = 37/71 (52%), Gaps = 10/71 (14%)
Query: 110 PCRNGGSCV-QPG--RCRCPAGWRGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWE 165
PCRNG CV QP CRC G+ G C +VD+CS C RCV+ S+ C C
Sbjct: 515 PCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSP--DPCHHGRCVDGIASFSCACAP 572
Query: 166 GHSLSADGTLC 176
G++ GT C
Sbjct: 573 GYT----GTRC 579
Score = 49.7 bits (117), Expect = 3e-06
Identities = 27/65 (41%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C P PC NGGSC V C C G+ G C DVDEC + G P C + S+ C
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCG-PGTCTDHVASFTCT 911
Query: 163 CWEGH 167
C G+
Sbjct: 912 CPPGY 916
Score = 49.3 bits (116), Expect = 4e-06
Identities = 35/105 (33%), Positives = 41/105 (39%), Gaps = 9/105 (8%)
Query: 70 RTAYRRSPGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQ-PGR---CRC 125
R RR P P P +G A + PC NGG C Q P R C C
Sbjct: 8 RRRRRRPMSPPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLC 67
Query: 126 PAGWRGDTCQSDVDEC----SARRGGCPQRCVNTAGSYWCQCWEG 166
P GW G+ CQ + D C A RG C V + C+C G
Sbjct: 68 PPGWVGERCQLE-DPCHSGPCAGRGVCQSSVVAGTARFSCRCPRG 111
Score = 47.4 bits (111), Expect = 1e-05
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 17/98 (17%)
Query: 109 PPCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSARRGGC----PQRCV-NTAGSYW 160
P C + G+CV RC CP G+ G C++D++EC R G C + C+ + G +
Sbjct: 1174 PRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINEC--RSGACHAAHTRDCLQDPGGGFR 1231
Query: 161 CQCWEGHSLSADGTLCVP-------KGGPPRVAPNPTG 191
C C G S T+ P GG R +P P G
Sbjct: 1232 CLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGG 1269
Score = 46.6 bits (109), Expect = 2e-05
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 15/72 (20%)
Query: 110 PCRNGGSCVQPGR-CRCPAGWRGDTCQSDVDECSARRGGCP------------QRCVNTA 156
PC+NGG CVQ G C CP GW G C D+ R +CV+
Sbjct: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLC--DIRSLPCREAAAQIGVRLEQLCQAGGQCVDED 1065
Query: 157 GSYWCQCWEGHS 168
S++C C EG +
Sbjct: 1066 SSHYCVCPEGRT 1077
Score = 46.2 bits (108), Expect = 3e-05
Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 21/154 (13%)
Query: 87 ACCPGWKRTSGLPGACGAAICQ---PPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDE 140
AC PG+ T C + + + PCR+GG C V CRCP+G G C+ ++D+
Sbjct: 569 ACAPGYTGTR-----CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDD 623
Query: 141 CSARRGGCP-QRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSAMKEE 199
C++ C C + Y C C G + G LC + +P G E
Sbjct: 624 CAS--NPCTFGVCRDGINRYDCVCQPGFT----GPLCNVEINECASSPCGEGGSCVDGEN 677
Query: 200 VQRLQSRVDLLEEKLQLVLAPLHSLASQALEHGL 233
R L L L P H A + HG+
Sbjct: 678 GFRCLCPPGSLP---PLCLPPSHPCAHEPCSHGI 708
Score = 44.7 bits (104), Expect = 9e-05
Identities = 35/86 (40%), Positives = 41/86 (47%), Gaps = 9/86 (10%)
Query: 110 PCRNGGSC--VQPG-RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC +GG C PG RC C + G CQ+ VD CS + RCV T G+Y C C G
Sbjct: 970 PCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT-GAY-CLCPPG 1027
Query: 167 HSLSADGTLCVPKGGPPRVAPNPTGV 192
S G LC + P R A GV
Sbjct: 1028 WS----GRLCDIRSLPCREAAAQIGV 1049
Score = 44.3 bits (103), Expect = 1e-04
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 7/69 (10%)
Query: 111 CRNGGSCVQP---GRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
C NGG+C C C GW G++C ++D+C+ C + S++C C G
Sbjct: 285 CHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGK 344
Query: 168 SLSADGTLC 176
+ G LC
Sbjct: 345 T----GLLC 349
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 21/99 (21%)
Query: 88 CCPGWKRTSGLPGACG-----AAICQPPCRNGGSCVQPGR---CRCPAGWRGDTCQSDVD 139
C PG+ GAC +I PC + G CV C+C G+ G C++DV+
Sbjct: 379 CPPGFTG-----GACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVN 433
Query: 140 ECSARRGGCPQR--CVNTAGSYWCQCWEGHSLSADGTLC 176
EC + G C + C++ G + C C G + GT C
Sbjct: 434 ECLS--GPCRNQATCLDRIGQFTCICMAGFT----GTYC 466
Score = 42.7 bits (99), Expect = 3e-04
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 11/67 (16%)
Query: 107 CQP-PCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSA---RRGGCPQRCVNTAGSY 159
C P PC +G CV C C G+ G C+S VDEC + R GG +C++ Y
Sbjct: 549 CSPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGG---KCLDLVDKY 604
Query: 160 WCQCWEG 166
C+C G
Sbjct: 605 LCRCPSG 611
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/100 (28%), Positives = 38/100 (38%), Gaps = 14/100 (14%)
Query: 110 PCRNGGSCVQ---PGRCRCPAGWRGDTCQSDVDECSAR---RGGCPQRCVNTAGSYWCQC 163
PCRN +C+ C C AG+ G C+ D+DEC + GG C + + C C
Sbjct: 439 PCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGV---CKDRVNGFSCTC 495
Query: 164 WEGHS-----LSADGTLCVPKGGPPRVAPNPTGVDSAMKE 198
G S L D P + P G + E
Sbjct: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAE 535
Score = 37.4 bits (85), Expect = 0.014
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 11/83 (13%)
Query: 96 SGLPGACGAAICQP-------PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARR 145
S LPG G + PC G+C V C CP G+ G C+ D+ +CS
Sbjct: 874 SCLPGFAGPRCARDVDECLSNPC-GPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSS 932
Query: 146 GGCPQRCVNTAGSYWCQCWEGHS 168
CV+ S+ C C G++
Sbjct: 933 CFNGGTCVDGVNSFSCLCRPGYT 955
Score = 36.6 bits (83), Expect = 0.024
Identities = 25/93 (26%), Positives = 35/93 (37%), Gaps = 9/93 (9%)
Query: 80 APARPRYACCP-GWKRT---SGLPGACGAAICQPP--CRNGGSCVQPGRCRCPAGWRGDT 133
AP + CP GW+ + G A C P C N C C G+ G +
Sbjct: 789 APGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFS---CTCHGGYTGPS 845
Query: 134 CQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
C D+++C C + GS+ C C G
Sbjct: 846 CDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPG 878
Score = 35.8 bits (81), Expect = 0.041
Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 10/66 (15%)
Query: 107 CQPP-CRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSAR---RGGCPQRCVNTAGSY 159
C P C NGG+CV C C G+ G CQ + D C +R GG C +
Sbjct: 928 CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGV---CSAAHPGF 984
Query: 160 WCQCWE 165
C C E
Sbjct: 985 RCTCLE 990
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG--RCRCPAGWRGDTCQSDV--DE 140
R C PG LP + A PC +G PG RC C GW G C + D
Sbjct: 680 RCLCPPGSLPPLCLPPSHPCA--HEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA 737
Query: 141 CSARRGGCPQRCVNTAGSYWCQCWEG 166
C ++ C + + C C G
Sbjct: 738 CESQPCRAGGTCSSDGMGFHCTCPPG 763
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 62.0 bits (149), Expect = 5e-10
Identities = 27/57 (47%), Positives = 35/57 (61%), Gaps = 3/57 (5%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC 163
PC+NGG+C + C+C +G+RG+ CQSD+DECS C NT GSY C C
Sbjct: 4097 PCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNC 4153
Score = 38.9 bits (89), Expect = 0.005
Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 4/58 (6%)
Query: 110 PCRNGGSCVQPGR----CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC 163
PC+NGG C C+C A + G C+ V+ CS++ CV G + CQC
Sbjct: 4021 PCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDNGGFVCQC 4078
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 61.2 bits (147), Expect = 9e-10
Identities = 41/135 (30%), Positives = 53/135 (39%), Gaps = 20/135 (14%)
Query: 53 LTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGW--KRTSGLPGACGAAICQPP 110
L C H C+ T P + R C G+ + AC + P
Sbjct: 308 LNYCGSHHPCTNGGTCINAE--------PDQYRCTCPDGYSGRNCEKAEHACTSN----P 355
Query: 111 CRNGGSC--VQPG-RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC---W 164
C NGGSC V G C CP+GW G TC D+DEC++ CV+ + C C W
Sbjct: 356 CANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQW 415
Query: 165 EGHSLSADGTLCVPK 179
G + D C K
Sbjct: 416 VGATCQLDANECEGK 430
Score = 54.7 bits (130), Expect = 9e-08
Identities = 22/60 (36%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PCRNGG+C V RC CP+GW G+ C ++ ++C RC + ++C C +G
Sbjct: 644 PCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDG 703
Score = 53.9 bits (128), Expect = 1e-07
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 9/97 (9%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSAR 144
C PGWK G+ C+ C++GG+C V +C CP G+ G C+ + DEC++
Sbjct: 449 CIPGWK---GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASS 505
Query: 145 RGGCPQRCVNTAGSYWCQCWEGHS---LSADGTLCVP 178
C + A + C C +G S D LC P
Sbjct: 506 PCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEP 542
Score = 53.9 bits (128), Expect = 1e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 18/92 (19%)
Query: 85 RYACCPGWKRTSGLPGACGAA---ICQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSD 137
R AC PGWK ++ C A C P PC NGG+CV G C C GW G TC +
Sbjct: 735 RCACPPGWKGST-----CAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHN 789
Query: 138 VDECS---ARRGGCPQRCVNTAGSYWCQCWEG 166
++C+ GG CV+ + C+C G
Sbjct: 790 TNDCNPLPCYNGGI---CVDGVNWFRCECAPG 818
Score = 49.3 bits (116), Expect = 4e-06
Identities = 22/57 (38%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 110 PCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC 163
PC +GG C C CP G+ G C+ DVD C RC N G Y+C C
Sbjct: 506 PCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCAC 562
Score = 49.3 bits (116), Expect = 4e-06
Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 17/92 (18%)
Query: 97 GLPGACGAAICQPPCRNGGSCV-QPG---RCRCPAGWRGDTCQSDVDEC---SARRGGCP 149
G+PG + +C P G CV QPG C C +G+ G C ++D+C R GG
Sbjct: 596 GMPGTAASGVCGPH----GRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGG-- 649
Query: 150 QRCVNTAGSYWCQC---WEGHSLSADGTLCVP 178
C++ ++ C C WEG + C+P
Sbjct: 650 -TCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 680
Score = 47.4 bits (111), Expect = 1e-05
Identities = 31/94 (32%), Positives = 36/94 (38%), Gaps = 16/94 (17%)
Query: 87 ACCPGWKRTSGLPGACGAAICQPPCRN-GGSCVQPGRCRCPAGWRGDTCQSDVDECSARR 145
AC GW + C A+C+ C G C PG CRC GW+G C DEC
Sbjct: 230 ACMDGW-----MGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFC----DECVPYP 280
Query: 146 GGCPQRCVNTAGSYWCQC---WEGHSLSADGTLC 176
G CV + C C W G D C
Sbjct: 281 GCVHGSCVE---PWQCNCETNWGGLLCDKDLNYC 311
Score = 46.2 bits (108), Expect = 3e-05
Identities = 27/86 (31%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSAR--- 144
C GW+ C + P C +G SCV+P +C C W G C D++ C +
Sbjct: 264 CSYGWQGRF-----CDECVPYPGCVHG-SCVEPWQCNCETNWGGLLCDKDLNYCGSHHPC 317
Query: 145 -RGGCPQRCVNT-AGSYWCQCWEGHS 168
GG C+N Y C C +G+S
Sbjct: 318 TNGG---TCINAEPDQYRCTCPDGYS 340
Score = 44.3 bits (103), Expect = 1e-04
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 107 CQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C P PC + G C V C C GW+G TC S +C A C ++ ++ C
Sbjct: 678 CLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCA 737
Query: 163 C---WEGHSLS-ADGTLCVP 178
C W+G + + A + C+P
Sbjct: 738 CPPGWKGSTCAVAKNSSCLP 757
Score = 38.1 bits (87), Expect = 0.008
Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 8/62 (12%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQ--RCVNTAGSYWCQCW 164
PC N SC + C C GW+G C +V++C RG C C + Y C C
Sbjct: 431 PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDC---RGQCQHGGTCKDLVNGYQCVCP 487
Query: 165 EG 166
G
Sbjct: 488 RG 489
Score = 33.1 bits (74), Expect = 0.27
Identities = 29/94 (30%), Positives = 34/94 (36%), Gaps = 25/94 (26%)
Query: 92 WKRTSGLPGACGAAI------CQP-PCRNGGSCVQP---GRCRCPAGWRGDTCQSDVD-- 139
W R PG G CQ PC G +CV RC CP G G CQ +
Sbjct: 810 WFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFG 869
Query: 140 -ECSARRGGCPQRCVNTAGSYW------CQCWEG 166
C +R P GS W C+C +G
Sbjct: 870 RSCWSRGTPFPH------GSSWVEDCNSCRCLDG 897
Score = 30.4 bits (67), Expect = 1.7
Identities = 26/88 (29%), Positives = 32/88 (36%), Gaps = 20/88 (22%)
Query: 104 AAICQPPCRNGG------SCVQPGRCRCPAGWRGDTCQSDV--DECSARRGGC--PQRCV 153
+A C CR +C Q G C GW G C+ V C+ GGC P C
Sbjct: 204 SATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECR 263
Query: 154 NTAGSYWCQCWEGHSLSADGTLCVPKGG 181
+ G W+G CVP G
Sbjct: 264 CSYG------WQGRFCDE----CVPYPG 281
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 61.2 bits (147), Expect = 9e-10
Identities = 57/186 (30%), Positives = 69/186 (37%), Gaps = 43/186 (23%)
Query: 40 VSESFVQRVYQPFLTTCD---GHRACSTYRTIYRTAYRRSPGLAPA-RPRYACCPGWKRT 95
V ES+ Q + T C C+ +R Y+TAYRR GL R R CCPG+ +
Sbjct: 38 VQESYAHPFDQIYYTRCTDILNWFKCTRHRISYKTAYRR--GLRTMYRRRSQCCPGYYES 95
Query: 96 SGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGG--CPQRCV 153
G +C C +G CV P C C GW G C S C + G C RC
Sbjct: 96 ----GDFCIPLCTEECVHG-RCVSPDTCHCEPGWGGPDCSSG---CDSDHWGPHCSNRCQ 147
Query: 154 NTAGSYW------CQC------WEGHSLSADGT---------------LCVPKGGPPRVA 186
G+ C C W L A GT C P+ G A
Sbjct: 148 CQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCA 207
Query: 187 PNPTGV 192
P TGV
Sbjct: 208 PGYTGV 213
Score = 51.6 bits (122), Expect = 7e-07
Identities = 40/134 (29%), Positives = 51/134 (38%), Gaps = 35/134 (26%)
Query: 87 ACCPGWKRTSGLPGACGAAICQP-----------PCRNGGSCVQ-PGRCRCPAGWRGDTC 134
AC PGW GA A C P PC +GG C G+C C AG+ GD C
Sbjct: 248 ACPPGWT------GAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRC 301
Query: 135 QSDV----------DECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG--GP 182
Q + C GG +C T G+ C+C G+ P+G GP
Sbjct: 302 QEECPFGSFGFQCSQHCDCHNGG---QCSPTTGA--CECEPGYKGPRCQERLCPEGLHGP 356
Query: 183 PRVAPNPTGVDSAM 196
P P D+ +
Sbjct: 357 GCTLPCPCDADNTI 370
Score = 44.3 bits (103), Expect = 1e-04
Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 27/113 (23%)
Query: 74 RRSPGLAPARPRYACCPGWKRTSGL-------PGACGAAI-CQPPCRNGGSCVQ-PGRCR 124
R P C PG+ +G+ PG+ GA + PC+NGG+C G C
Sbjct: 192 RHGASCDPRAGECLCAPGY---TGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECA 248
Query: 125 CPAGWRGDTC----------QSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
CP GW G C Q+ +C GG +C + G C C G+
Sbjct: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG---QCDHVTGQ--CHCTAGY 296
Score = 38.5 bits (88), Expect = 0.006
Identities = 41/141 (29%), Positives = 52/141 (36%), Gaps = 34/141 (24%)
Query: 52 FLTTCDGHRACSTYRTIYRTAYRRSPGLAPARPRYACCPGWKR----TSGLPGACG---A 104
F C H CS + G P C GW ++ PG G +
Sbjct: 528 FGLNCSEHCDCS-----------HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCS 576
Query: 105 AICQPPCRNGGSCV-QPGRCRCPAGWRGDTCQSDVDECSARRGGCPQ---RCVNTAG--- 157
C C NGGSC + G C C G+RG CQ + GC Q CV+++
Sbjct: 577 VSCS--CENGGSCSPEDGSCECAPGFRGPLCQR-ICPPGFYGHGCAQPCPLCVHSSRPCH 633
Query: 158 --SYWCQCWEGHSLSADGTLC 176
S C+C G S G LC
Sbjct: 634 HISGICECLPGFS----GALC 650
Score = 38.1 bits (87), Expect = 0.008
Identities = 29/101 (28%), Positives = 36/101 (35%), Gaps = 19/101 (18%)
Query: 77 PGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQ-PGRCRCPAGWRGDTCQ 135
PG + A C G+ G A +C C N G+C G C+C GW G C
Sbjct: 643 PGFSGALCNQVCAGGYF------GQDCAQLCS--CANNGTCSPIDGSCQCFPGWIGKDCS 694
Query: 136 SDVDECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
CP A + C C G S SA+ C
Sbjct: 695 Q----------ACPPGFWGPACFHACSCHNGASCSAEDGAC 725
Score = 38.1 bits (87), Expect = 0.008
Identities = 28/84 (33%), Positives = 33/84 (39%), Gaps = 26/84 (30%)
Query: 88 CCPGWKR---TSGLPGA-----CGAAICQPPCRNGGSCVQ-PGRCRCPAGWRGDTCQSDV 138
C PGW T P A CG +CQ C+NG SC G+C C G+ G C+
Sbjct: 727 CTPGWTGLFCTQRCPAAFFGKDCGR-VCQ--CQNGASCDHISGKCTCRTGFTGQHCE--- 780
Query: 139 DECSARRGGCPQRCVNTAGSYWCQ 162
QRC Y CQ
Sbjct: 781 -----------QRCAPGTFGYGCQ 793
Score = 37.4 bits (85), Expect = 0.014
Identities = 31/100 (31%), Positives = 33/100 (33%), Gaps = 16/100 (16%)
Query: 88 CCPGW--KRTSGL--PGACGAAICQP-PCRNGGSC-VQPGRCRCPAGWRGDTCQSDVDEC 141
C PGW K S PG G A C NG SC + G C C GW G C
Sbjct: 684 CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQ----- 738
Query: 142 SARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGG 181
CP CQC G S C + G
Sbjct: 739 -----RCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTG 773
Score = 36.2 bits (82), Expect = 0.032
Identities = 35/116 (30%), Positives = 38/116 (32%), Gaps = 22/116 (18%)
Query: 81 PARPRYACCPGWKR---TSGLPGACGAAICQPPC--RNGGSCVQ-PGRCRCPAGWRGDTC 134
P C PGW P CQ PC +NG C G C C G+ G+ C
Sbjct: 374 PVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVC 433
Query: 135 QSDV----------DECSARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKG 180
CS GG C GS C C EG D TL P G
Sbjct: 434 AVSCAAGTYGPNCSSICSCNNGG---TCSPVDGS--CTCKEGWQ-GLDCTLPCPSG 483
Score = 35.4 bits (80), Expect = 0.054
Identities = 38/145 (26%), Positives = 46/145 (31%), Gaps = 34/145 (23%)
Query: 80 APARPRYACCPGWKR---TSGLPGACGAAICQPPCR--NGGSCVQ-PGRCRCPAGWRGDT 133
+P C GW+ T P C C NG +C G C C GW GDT
Sbjct: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDT 518
Query: 134 CQ------------------SDVDECSARRGGC-------PQRCVNTA--GSYWCQCWEG 166
C+ S D C G C RC +T G + C
Sbjct: 519 CELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVS 578
Query: 167 HSLSADGTLCVPKGGPPRVAPNPTG 191
S G+ C P+ G AP G
Sbjct: 579 CSCENGGS-CSPEDGSCECAPGFRG 602
Score = 29.6 bits (65), Expect = 3.0
Identities = 29/106 (27%), Positives = 32/106 (30%), Gaps = 20/106 (18%)
Query: 77 PGLAPARPRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQ-PGRCRCPAGWRGDTCQ 135
PG R + CP GL G C N SC G C C GW G C
Sbjct: 337 PGYKGPRCQERLCP-----EGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN 391
Query: 136 SDVDECSARRGGCPQRCVNTAGSYWCQCWEG---HSLSADGTLCVP 178
CP C C G HS++ G C P
Sbjct: 392 E----------SCPVGYYGDGCQLPCTCQNGADCHSITG-GCTCAP 426
>gi|148886692 FAT tumor suppressor homolog 3 [Homo sapiens]
Length = 4557
Score = 60.8 bits (146), Expect = 1e-09
Identities = 40/99 (40%), Positives = 46/99 (46%), Gaps = 12/99 (12%)
Query: 107 CQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C P PCRNGGSC G C C AG G TC+ D++EC CVN GS+ C
Sbjct: 4064 CFPNPCRNGGSCDPIGNTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCN 4123
Query: 163 CWEGHSLSADGTLCVPKGGPPRVAPN-PTGVDSAMKEEV 200
C G+ G C G P V PN G KEE+
Sbjct: 4124 CTPGYV----GQYC---GLRPVVVPNIQAGHSYVGKEEL 4155
Score = 35.4 bits (80), Expect = 0.054
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 14/75 (18%)
Query: 99 PGACGAAICQPPCRNGGSCVQ-PG---RCRCPAGWRGDTCQSDVDEC---SARRGGCPQR 151
P AC + PC++GGSC P +C C + + G C+S++ C R GG
Sbjct: 4022 PDACKRS----PCQHGGSCTGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGG---S 4074
Query: 152 CVNTAGSYWCQCWEG 166
C ++ C C G
Sbjct: 4075 CDPIGNTFICNCKAG 4089
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 60.1 bits (144), Expect = 2e-09
Identities = 36/100 (36%), Positives = 46/100 (46%), Gaps = 17/100 (17%)
Query: 85 RYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPG---RCRCPAGWR-GDTCQS--DV 138
R C +PG C GG+C+ CRCPAG + +T Q D+
Sbjct: 270 RTGACQDVDECQAIPGIC----------QGGNCINTVGSFECRCPAGHKQSETTQKCEDI 319
Query: 139 DECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
DECS G C C NT GSY+C C G+ S DG+ C+
Sbjct: 320 DECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCI 359
Score = 58.5 bits (140), Expect = 6e-09
Identities = 28/71 (39%), Positives = 38/71 (53%), Gaps = 5/71 (7%)
Query: 111 CRNGGSCVQPG--RCRCPAGWRGDTCQ---SDVDECSARRGGCPQRCVNTAGSYWCQCWE 165
CRNG G +C C G++ + +D+DEC GGC +C N+ GSY C C E
Sbjct: 1211 CRNGKCVNMIGTYQCSCNPGYQATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSE 1270
Query: 166 GHSLSADGTLC 176
G++L DG C
Sbjct: 1271 GYALMPDGRSC 1281
Score = 57.0 bits (136), Expect = 2e-08
Identities = 38/107 (35%), Positives = 48/107 (44%), Gaps = 20/107 (18%)
Query: 75 RSPGLAPARPRYACCPGWKRTSGLPGA--CGAAICQPPCRNGGSCVQPGRCRCPAGWRGD 132
R P + +R CCPGWK LPG C IC+ C G C +P C C +G
Sbjct: 84 RGPNVCGSRFHSYCCPGWKT---LPGGNQCIVPICRNSC-GDGFCSRPNMCTCSSGQISS 139
Query: 133 TCQS-DVDECSARRGGCPQRCVN--TAGSYWCQCWEGHSLSADGTLC 176
TC S + +CS RC+N T CQC +G+ GT C
Sbjct: 140 TCGSKSIQQCSV-------RCMNGGTCADDHCQCQKGYI----GTYC 175
Score = 53.9 bits (128), Expect = 1e-07
Identities = 34/114 (29%), Positives = 49/114 (42%), Gaps = 10/114 (8%)
Query: 26 PGRRVCAVRAHGDPVSESFVQRVYQPFLTTCDGHRACSTY--RTIYRTAYRRSPGLAPAR 83
PG C V + + F R P + TC + ST ++I + + R G A
Sbjct: 105 PGGNQCIVPICRNSCGDGFCSR---PNMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCAD 161
Query: 84 PRYACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSD 137
C G+ T CG +C+ C+NGG C+ P RC C G+ G C+ D
Sbjct: 162 DHCQCQKGYIGTY-----CGQPVCENGCQNGGRCIGPNRCACVYGFTGPQCERD 210
Score = 52.8 bits (125), Expect = 3e-07
Identities = 33/74 (44%), Positives = 39/74 (52%), Gaps = 6/74 (8%)
Query: 110 PCRNGGSCVQPGR--CRCPAGW-RGDTCQS--DVDECSARRGGCPQ-RCVNTAGSYWCQC 163
PC NG PG C+C AG+ R T Q+ D+DEC C RCVNT GS+ C C
Sbjct: 543 PCTNGDCVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCIC 602
Query: 164 WEGHSLSADGTLCV 177
G L+ DG CV
Sbjct: 603 NAGFELTTDGKNCV 616
Score = 51.6 bits (122), Expect = 7e-07
Identities = 42/121 (34%), Positives = 53/121 (43%), Gaps = 32/121 (26%)
Query: 88 CCPGWKRTS-------GLPGACGAAICQPPCR---NGGS-----CVQPG--------RCR 124
C PG K +S L G C I C NG + C G RC
Sbjct: 877 CSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE 936
Query: 125 ----CPAGW---RGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLC 176
CP G +G TC+ DV+EC G CP RCVN+ GS+ C+C EG +L G +C
Sbjct: 937 LDTACPRGLARIKGVTCE-DVNECEVFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVC 995
Query: 177 V 177
+
Sbjct: 996 L 996
Score = 50.1 bits (118), Expect = 2e-06
Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 5/71 (7%)
Query: 111 CRNGGSCVQPG--RCRCPAGWRGD---TCQSDVDECSARRGGCPQRCVNTAGSYWCQCWE 165
C NG G RC C G+ D T D+DECS C C NT GSY C C
Sbjct: 2460 CTNGQCINTMGSFRCFCKVGYTTDISGTSCIDLDECSQSPKPCNYICKNTEGSYQCSCPR 2519
Query: 166 GHSLSADGTLC 176
G+ L DG C
Sbjct: 2520 GYVLQEDGKTC 2530
Score = 49.7 bits (117), Expect = 3e-06
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 10/72 (13%)
Query: 99 PGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQS---DVDECSARRGGCPQRCVNT 155
P ACG+A C + + +C CP+G+ D S DV+ECS+ + C C NT
Sbjct: 2661 PNACGSASCY-------NTLGSYKCACPSGFSFDQFSSACHDVNECSSSKNPCNYGCSNT 2713
Query: 156 AGSYWCQCWEGH 167
G Y C C G+
Sbjct: 2714 EGGYLCGCPPGY 2725
Score = 48.9 bits (115), Expect = 5e-06
Identities = 35/98 (35%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRN---GGSCVQ-PG--RCRCPAGWRGDTCQS-DVDE 140
C G+ G G C+ N SC+ PG +C C GW G+ + D+DE
Sbjct: 1352 CQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDE 1411
Query: 141 CSARRGGCP--QRCVNTAGSYWCQCWEGHSLSADGTLC 176
CS C +CVNT GSY C C EG + DG C
Sbjct: 1412 CSNGTHQCSINAQCVNTPGSYRCACSEG--FTGDGFTC 1447
Score = 48.9 bits (115), Expect = 5e-06
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 111 CRNGGSCVQ-PG--RCRCPAGWRGD--TCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCW 164
C CV PG RC C G+ GD TC SDVDEC+ C +C+N G+Y C+C
Sbjct: 1419 CSINAQCVNTPGSYRCACSEGFTGDGFTC-SDVDECAENINLCENGQCLNVPGAYRCECE 1477
Query: 165 EGHSLSADGTLC 176
G + ++D C
Sbjct: 1478 MGFTPASDSRSC 1489
Score = 47.4 bits (111), Expect = 1e-05
Identities = 27/78 (34%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Query: 107 CQPPCRNGGSCVQPGRCRCPAGW----RGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQ 162
C C+N Q C CP G+ G TC+ D+DEC ++ C CVNT G + C+
Sbjct: 2502 CNYICKNTEGSYQ---CSCPRGYVLQEDGKTCK-DLDECQTKQHNCQFLCVNTLGGFTCK 2557
Query: 163 CWEG----HSLSADGTLC 176
C G H+ D C
Sbjct: 2558 CPPGFTQHHTACIDNNEC 2575
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/60 (43%), Positives = 32/60 (53%), Gaps = 6/60 (10%)
Query: 123 CRCPAGWR----GDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
C CP G G+ C D +EC + G C RCVN GSY C+C EG S+ GT C+
Sbjct: 2321 CICPPGMARRPDGEGCV-DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECL 2379
Score = 45.1 bits (105), Expect = 7e-05
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 110 PCRNGG--SCVQPGRCRCPAGWRGDTCQS--DVDECSARRGGCPQRCVNTAGSYWCQCWE 165
PC NG + + C C G+ + D++EC+ C RC+NT GSY C C
Sbjct: 2222 PCGNGTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPI 2281
Query: 166 GHSLSADGTLC 176
G++L D +C
Sbjct: 2282 GYALREDQKMC 2292
Score = 44.3 bits (103), Expect = 1e-04
Identities = 29/74 (39%), Positives = 36/74 (48%), Gaps = 19/74 (25%)
Query: 98 LPGACGAAICQPPCRNGGSCVQPG---RCRCPAGW--RGDT--CQSDVDECSARRGGC-P 149
LPG C GG+C+ +C CP G+ DT C+ D+DEC A G C P
Sbjct: 1657 LPGLC----------QGGNCINTFGSFQCECPQGYYLSEDTRICE-DIDECFAHPGVCGP 1705
Query: 150 QRCVNTAGSYWCQC 163
C NT G+Y C C
Sbjct: 1706 GTCYNTLGNYTCIC 1719
Score = 43.5 bits (101), Expect = 2e-04
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 8/75 (10%)
Query: 110 PCRNGG--SCVQPGRCRCPAGWR---GDTCQSDVDECSARRGGCPQ--RCVNTAGSYWCQ 162
PC NG + V C C G+ + C D+DECS+ G + RC N GS+ C
Sbjct: 1942 PCGNGTCKNTVGSYNCLCYPGFELTHNNDCL-DIDECSSFFGQVCRNGRCFNEIGSFKCL 2000
Query: 163 CWEGHSLSADGTLCV 177
C EG+ L+ DG C+
Sbjct: 2001 CNEGYELTPDGKNCI 2015
Score = 43.5 bits (101), Expect = 2e-04
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 117 CVQPGRCR----CPAGWRGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSA 171
C PG + CP G T D+DEC C +C+NT GS+ C C G++
Sbjct: 2425 CPLPGTAQYKKICPHGPGYTTDGRDIDECKVMPNLCTNGQCINTMGSFRCFCKVGYTTDI 2484
Query: 172 DGTLCV 177
GT C+
Sbjct: 2485 SGTSCI 2490
Score = 43.1 bits (100), Expect = 3e-04
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 3/57 (5%)
Query: 123 CRCPAGW-RGDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQCWEGHSLSADGTLC 176
C+CP G+ + T D +EC ++ C + C NT GS+ C+C G SL A G C
Sbjct: 2556 CKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNC 2612
Score = 42.7 bits (99), Expect = 3e-04
Identities = 30/102 (29%), Positives = 41/102 (40%), Gaps = 14/102 (13%)
Query: 87 ACCPGWKRTSGLPGACGAAICQPPCRNGGSCVQ------PGRCRCPAGWR----GDTCQS 136
+C PG++ T G C NGG Q C C G+ G +C +
Sbjct: 1226 SCNPGYQATPDRQGCTDIDECM--IMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC-A 1282
Query: 137 DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
D+DEC C +C N G Y C C++G S D C+
Sbjct: 1283 DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKTCI 1324
Score = 42.4 bits (98), Expect = 4e-04
Identities = 26/74 (35%), Positives = 37/74 (50%), Gaps = 10/74 (13%)
Query: 111 CRNGGSCVQPGR--CRCPAGW----RGDTCQSDVDECSARRGGCPQ-RCVNTAGSYWCQC 163
C NG PG C CP G+ +TC+ D++EC + C C N GS+ C+C
Sbjct: 821 CDNGLCRNTPGSYSCTCPPGYVFRTETETCE-DINECESNP--CVNGACRNNLGSFNCEC 877
Query: 164 WEGHSLSADGTLCV 177
G LS+ G +C+
Sbjct: 878 SPGSKLSSTGLICI 891
Score = 42.4 bits (98), Expect = 4e-04
Identities = 31/87 (35%), Positives = 35/87 (40%), Gaps = 18/87 (20%)
Query: 99 PGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQS----DVDECSAR----RGGCPQ 150
P CG+ IC GS C C G+ D+DEC RGG
Sbjct: 1123 PDLCGSGIC---VNTPGSF----ECECFEGYESGFMMMKNCMDIDECERNPLLCRGGT-- 1173
Query: 151 RCVNTAGSYWCQCWEGHSLSADGTLCV 177
CVNT GS+ C C GH LS CV
Sbjct: 1174 -CVNTEGSFQCDCPLGHELSPSREDCV 1199
Score = 42.4 bits (98), Expect = 4e-04
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 11/82 (13%)
Query: 98 LPGACGAAICQPPCRNGGSCVQPGRCRCPAGW--RGDTCQSDVDECSARRGGCP-QRCVN 154
LPG+C CQ + RC CP G+ + + C D++EC C C N
Sbjct: 2023 LPGSCSPGTCQ-------NLEGSFRCICPPGYEVKSENC-IDINECDEDPNICLFGSCTN 2074
Query: 155 TAGSYWCQCWEGHSLSADGTLC 176
T G + C C G LS +G C
Sbjct: 2075 TPGGFQCLCPPGFVLSDNGRRC 2096
Score = 42.0 bits (97), Expect = 6e-04
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 1/41 (2%)
Query: 137 DVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLC 176
D+DEC G C C+NT GS+ C+C +G+ LS D +C
Sbjct: 1650 DIDECQELPGLCQGGNCINTFGSFQCECPQGYYLSEDTRIC 1690
Score = 41.6 bits (96), Expect = 8e-04
Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 7/73 (9%)
Query: 111 CRNGGSCVQPG--RCRCPAGW----RGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCW 164
C NG + G +C C G+ G C +DVDEC C+N+ GS+ C C
Sbjct: 627 CLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGICMNGHCINSEGSFRCDCP 685
Query: 165 EGHSLSADGTLCV 177
G ++ DG +CV
Sbjct: 686 PGLAVGMDGRVCV 698
Score = 41.2 bits (95), Expect = 0.001
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 111 CRNGGSCVQ-PG--RCRCPAGWRGDTCQSDVD--ECSARRGGCPQR-CVNTAGSYWCQCW 164
C+ C+ PG RC C AG++ + VD EC C CV+ GSY C C
Sbjct: 1861 CQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHGLCVDLQGSYQCICH 1920
Query: 165 EGHSLSADGTLCV 177
G S D T+C+
Sbjct: 1921 NGFKASQDQTMCM 1933
Score = 39.7 bits (91), Expect = 0.003
Identities = 18/44 (40%), Positives = 26/44 (59%), Gaps = 1/44 (2%)
Query: 135 QSDVDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADGTLCV 177
+ DV+EC G C +C+NT GS+ C+C G++L G CV
Sbjct: 2169 REDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYTGVRCV 2212
Score = 39.3 bits (90), Expect = 0.004
Identities = 28/76 (36%), Positives = 34/76 (44%), Gaps = 9/76 (11%)
Query: 109 PPCRNGGSCVQ-PG--RCRCPAGWRGD----TCQSDVDECSARRGGCP-QRCVNTAGSYW 160
P +GG C PG RC C G+ TC DV+EC C C NT GS+
Sbjct: 1291 PDICDGGQCTNIPGEYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMFGECENTKGSFI 1349
Query: 161 CQCWEGHSLSADGTLC 176
C C G+S+ T C
Sbjct: 1350 CHCQLGYSVKKGTTGC 1365
Score = 39.3 bits (90), Expect = 0.004
Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 12/76 (15%)
Query: 107 CQPPCRN--GGSCVQPGRCRCPAGW----RGDTCQSDVDECSARRGGCPQRCVNTAGSYW 160
CQ C+N GG RC CP G+ + + C D +ECS C NT GSY
Sbjct: 2624 CQHGCQNILGGY-----RCGCPQGYIQHYQWNQCV-DENECSNPNACGSASCYNTLGSYK 2677
Query: 161 CQCWEGHSLSADGTLC 176
C C G S + C
Sbjct: 2678 CACPSGFSFDQFSSAC 2693
Score = 37.4 bits (85), Expect = 0.014
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 111 CRNGGSCVQPG--RCRCPAGWR----GDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCW 164
C+NG G +C C AG+ G C D DEC+ C+N GS+ C C
Sbjct: 586 CKNGRCVNTDGSFQCICNAGFELTTDGKNCV-DHDECTTTNMCLNGMCINEDGSFKCICK 644
Query: 165 EGHSLSADGTLC 176
G L+ +G C
Sbjct: 645 PGFVLAPNGRYC 656
Score = 36.6 bits (83), Expect = 0.024
Identities = 25/74 (33%), Positives = 33/74 (44%), Gaps = 14/74 (18%)
Query: 117 CVQPG----RCRCPAGW----RGDTCQS-----DVDECSARRGGCPQ-RCVNTAGSYWCQ 162
C +PG CP G RGD D++EC A G C +C NT GS+ C+
Sbjct: 1040 CPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCR 1099
Query: 163 CWEGHSLSADGTLC 176
C G +L + C
Sbjct: 1100 CNSGFALDMEERNC 1113
Score = 36.6 bits (83), Expect = 0.024
Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 8/70 (11%)
Query: 115 GSCVQ-PG--RCRCPAGWR----GDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEGH 167
G+C PG C C G+ G C +D+DEC+ CVNT G Y C C
Sbjct: 1504 GTCNNLPGMFHCICDDGYELDRTGGNC-TDIDECADPINCVNGLCVNTPGRYECNCPPDF 1562
Query: 168 SLSADGTLCV 177
L+ G CV
Sbjct: 1563 QLNPTGVGCV 1572
Score = 36.6 bits (83), Expect = 0.024
Identities = 33/104 (31%), Positives = 38/104 (36%), Gaps = 22/104 (21%)
Query: 99 PGACGA-AICQPPCRNGGSCVQPGR--CRCPAGWRGDT----CQSDVDECSARRGGCPQR 151
P CGA ICQ PG C C G+ D C+ DVDEC C
Sbjct: 2579 PSLCGAKGICQNT---------PGSFSCECQRGFSLDATGLNCE-DVDECDGNHR-CQHG 2627
Query: 152 CVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSA 195
C N G Y C C +G+ CV + NP SA
Sbjct: 2628 CQNILGGYRCGCPQGYIQHYQWNQCVDE----NECSNPNACGSA 2667
Score = 35.8 bits (81), Expect = 0.041
Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 6/61 (9%)
Query: 123 CRCPAGWRGDTCQS---DVDECSARRGGCPQR---CVNTAGSYWCQCWEGHSLSADGTLC 176
C CP G+ Q D+DEC+ C R C N G++ C C G + DG C
Sbjct: 2277 CTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC 2336
Query: 177 V 177
V
Sbjct: 2337 V 2337
Score = 34.7 bits (78), Expect = 0.092
Identities = 24/72 (33%), Positives = 29/72 (40%), Gaps = 4/72 (5%)
Query: 107 CQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQR-CVNTAGSYWCQCWE 165
CQP C S G C G D D++EC+ C C N GSY C C
Sbjct: 741 CQP-CPAKNSAEFHGLCSSGVGITVDG--RDINECALDPDICANGICENLRGSYRCNCNS 797
Query: 166 GHSLSADGTLCV 177
G+ A G C+
Sbjct: 798 GYEPDASGRNCI 809
Score = 31.2 bits (69), Expect = 1.0
Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)
Query: 137 DVDECSARRGGCPQR-CVNTAGSYWCQCWEGHS 168
D+DEC G C C+N GS+ C+C G S
Sbjct: 1808 DIDECKEIPGICANGVCINQIGSFRCECPTGFS 1840
Score = 28.1 bits (61), Expect = 8.6
Identities = 13/37 (35%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 138 VDECSARRGGCPQ-RCVNTAGSYWCQCWEGHSLSADG 173
+D C C RC+ T SY C+C G+ A+G
Sbjct: 495 IDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANG 531
Score = 28.1 bits (61), Expect = 8.6
Identities = 18/76 (23%), Positives = 27/76 (35%), Gaps = 17/76 (22%)
Query: 99 PGACGAAICQ----------PP----CRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSAR 144
PG CG C PP G +C+ + C + G TC++++ +
Sbjct: 1700 PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTK 1759
Query: 145 RGGCPQRCVNTAGSYW 160
R C C G W
Sbjct: 1760 RMCC---CTYNVGKAW 1772
>gi|9966885 tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 60.1 bits (144), Expect = 2e-09
Identities = 34/83 (40%), Positives = 37/83 (44%), Gaps = 7/83 (8%)
Query: 102 CGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQS----DVDECSARRGGCPQRCVNTAG 157
C A C+ C GG Q C C G+R D DEC G C Q CVN G
Sbjct: 275 CAQAPCEQQCEPGGP--QGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVG 331
Query: 158 SYWCQCWEGHSLSADGTLCVPKG 180
+ C C EGH L ADG C P G
Sbjct: 332 GFECYCSEGHELEADGISCSPAG 354
Score = 37.0 bits (84), Expect = 0.018
Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Query: 141 CSARRGGCPQRCVNTA-GSYWCQCWEGHSLSADGTLC 176
CS GGC CV G C+C EG L+ADG C
Sbjct: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC 271
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 59.7 bits (143), Expect = 3e-09
Identities = 31/83 (37%), Positives = 40/83 (48%), Gaps = 7/83 (8%)
Query: 88 CCPGWKRTSGLPGACGAAICQPP-CRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSA 143
C PGW +G + C P C +GG+C V +C CP W G TCQ D +EC A
Sbjct: 362 CSPGW---TGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA 418
Query: 144 RRGGCPQRCVNTAGSYWCQCWEG 166
+ + C N SY+C C G
Sbjct: 419 KPCVNAKSCKNLIASYYCDCLPG 441
Score = 54.3 bits (129), Expect = 1e-07
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 14/94 (14%)
Query: 88 CCPGWKRTSGLPGACGAAI--CQPPCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECS 142
C PGW + C I C C+N SC V RC CP G+ GD C+ D+DEC+
Sbjct: 438 CLPGWMGQN-----CDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECA 492
Query: 143 ARRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLC 176
+ C N + C C G S G LC
Sbjct: 493 SNPCLNGGHCQNEINRFQCLCPTGFS----GNLC 522
Score = 53.5 bits (127), Expect = 2e-07
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 6/81 (7%)
Query: 105 AICQPPCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWC 161
A PC N GSC + C C GW G TC +++D+CS C + + C
Sbjct: 339 ACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKC 398
Query: 162 QC---WEGHSLSADGTLCVPK 179
C W G + D C K
Sbjct: 399 VCPPQWTGKTCQLDANECEAK 419
Score = 53.5 bits (127), Expect = 2e-07
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 3/61 (4%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQCWEG 166
PC NGG C + +C CP G+ G+ CQ D+D C +C N A Y+C+C E
Sbjct: 495 PCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPED 554
Query: 167 H 167
+
Sbjct: 555 Y 555
Score = 53.1 bits (126), Expect = 2e-07
Identities = 35/112 (31%), Positives = 45/112 (40%), Gaps = 11/112 (9%)
Query: 88 CCPGWKRTSGLPGACGAAICQP-PCRNGGSCVQPG---RCRCPAGWRGDTCQSDVDECSA 143
C GW+ G A C P PC N G+CV RC C G+ G C+ +++EC +
Sbjct: 770 CKEGWE---GPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQS 826
Query: 144 RRGGCPQRCVNTAGSYWCQCWEGHSLSADGTLCVPKGGPPRVAPNPTGVDSA 195
CV+ Y C C GHS G C G P + D A
Sbjct: 827 SPCAFGATCVDEINGYRCVCPPGHS----GAKCQEVSGRPCITMGSVIPDGA 874
Score = 51.2 bits (121), Expect = 9e-07
Identities = 22/73 (30%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 110 PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSARRGGCPQRCVNTAGSYWCQC--- 163
PCRNGG+C V +C C GW G C++++++CS C + ++C C
Sbjct: 637 PCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNG 696
Query: 164 WEGHSLSADGTLC 176
W+G + + + C
Sbjct: 697 WKGKTCHSRDSQC 709
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/86 (36%), Positives = 39/86 (45%), Gaps = 13/86 (15%)
Query: 89 CPG-WKRTSGLPGACGAA---ICQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDE 140
CPG W+ T+ C A C P PC NGG+CV G C C GW G C + ++
Sbjct: 731 CPGGWEGTT-----CNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTND 785
Query: 141 CSARRGGCPQRCVNTAGSYWCQCWEG 166
CS CV+ Y C+C G
Sbjct: 786 CSPHPCYNSGTCVDGDNWYRCECAPG 811
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/81 (35%), Positives = 39/81 (48%), Gaps = 13/81 (16%)
Query: 108 QPPCRNGGSC---VQPGRCRCPAGWRGDTC---QSDVDECSARRGGCPQRCVNTAGSYWC 161
Q PC NGG+C V C C GW+G TC S DE + GG C + ++ C
Sbjct: 673 QNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGG---TCYDEGDAFKC 729
Query: 162 QC---WEGHSLS-ADGTLCVP 178
C WEG + + A + C+P
Sbjct: 730 MCPGGWEGTTCNIARNSSCLP 750
Score = 45.1 bits (105), Expect = 7e-05
Identities = 30/91 (32%), Positives = 35/91 (38%), Gaps = 12/91 (13%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCR-NGGSCVQPGRCRCPAGWRGDTCQSDVDECSARRG 146
C GW + C AIC+ C GSC PG CRC GW+G C D+C
Sbjct: 220 CMEGW-----MGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLYC----DKC-IPHP 269
Query: 147 GCPQRCVNTAGSYWCQC-WEGHSLSADGTLC 176
GC N C+ W G D C
Sbjct: 270 GCVHGICNEPWQCLCETNWGGQLCDKDLNYC 300
Score = 45.1 bits (105), Expect = 7e-05
Identities = 30/86 (34%), Positives = 38/86 (44%), Gaps = 14/86 (16%)
Query: 88 CCPGWKRTSGLPGACGAAICQPPCRNGGSCVQPGRCRCPAGWRGDTCQSDVDECSARR-- 145
C GW+ GL C I P C +G C +P +C C W G C D++ C +
Sbjct: 253 CQYGWQ---GL--YCDKCIPHPGCVHG-ICNEPWQCLCETNWGGQLCDKDLNYCGTHQPC 306
Query: 146 --GGCPQRCVNTA-GSYWCQCWEGHS 168
GG C NT Y C C EG+S
Sbjct: 307 LNGG---TCSNTGPDKYQCSCPEGYS 329
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 11/78 (14%)
Query: 110 PCRNGGSCVQPG----RCRCPAGWRGDTCQSDVDECSARRGGCPQR--CVNTAGSYWCQC 163
PC NGG+C G +C CP G+ G C ++ E + C R C T+ + C+C
Sbjct: 305 PCLNGGTCSNTGPDKYQCSCPEGYSGPNC--EIAEHACLSDPCHNRGSCKETSLGFECEC 362
Query: 164 ---WEGHSLSADGTLCVP 178
W G + S + C P
Sbjct: 363 SPGWTGPTCSTNIDDCSP 380
Score = 36.6 bits (83), Expect = 0.024
Identities = 25/87 (28%), Positives = 35/87 (40%), Gaps = 12/87 (13%)
Query: 88 CCPGWKRTSGLPGACGAAICQP-PCRNGGSC---VQPGRCRCPAGWRGDTCQSDVDECSA 143
C P W +G A C+ PC N SC + C C GW G C ++++C
Sbjct: 400 CPPQW---TGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDC-- 454
Query: 144 RRGGCPQ--RCVNTAGSYWCQCWEGHS 168
G C C + Y C C G++
Sbjct: 455 -LGQCQNDASCRDLVNGYRCICPPGYA 480
Score = 34.7 bits (78), Expect = 0.092
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 9/50 (18%)
Query: 123 CRCPAGWRGDTCQSDVDECSA---RRGGCPQRCVNTAGSYWCQC---WEG 166
C C G+ G C ++++C + R GG C++ SY C C WEG
Sbjct: 615 CDCNKGFTGTYCHENINDCESNPCRNGG---TCIDGVNSYKCICSDGWEG 661
Score = 33.5 bits (75), Expect = 0.20
Identities = 14/39 (35%), Positives = 18/39 (46%), Gaps = 4/39 (10%)
Query: 107 CQP-PCRNGGSCVQPGR---CRCPAGWRGDTCQSDVDEC 141
C+P PC+NG C C+CP + G C D C
Sbjct: 529 CEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHC 567
Score = 29.6 bits (65), Expect = 3.0
Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 12/69 (17%)
Query: 116 SCVQPGRCRCPAGWRGDTCQSDV--DECSARRGGCPQRCVNTAGSYWCQC-WEGHSLSAD 172
+C Q G C GW G C + CS + G C G CQ W+G L D
Sbjct: 211 ACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSC-----KLPGDCRCQYGWQG--LYCD 263
Query: 173 GTLCVPKGG 181
C+P G
Sbjct: 264 --KCIPHPG 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,678,448
Number of Sequences: 37866
Number of extensions: 745011
Number of successful extensions: 4578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 233
Number of HSP's successfully gapped in prelim test: 178
Number of HSP's that attempted gapping in prelim test: 2555
Number of HSP's gapped (non-prelim): 1610
length of query: 273
length of database: 18,247,518
effective HSP length: 101
effective length of query: 172
effective length of database: 14,423,052
effective search space: 2480764944
effective search space used: 2480764944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.