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Search of human proteins with 41393554
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41393554 LUC7-like isoform b [Homo sapiens]
(371 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41393554 LUC7-like isoform b [Homo sapiens] 731 0.0
gi|8922297 LUC7-like isoform a [Homo sapiens] 639 0.0
gi|116812577 LUC7-like 2 [Homo sapiens] 540 e-154
gi|52426743 cisplatin resistance-associated overexpressed protei... 212 4e-55
gi|19923485 cisplatin resistance-associated overexpressed protei... 212 4e-55
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 89 8e-18
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 89 8e-18
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 85 1e-16
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 79 7e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 76 4e-14
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 75 9e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 74 2e-13
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 74 2e-13
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 73 4e-13
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 73 4e-13
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 71 2e-12
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 71 2e-12
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 70 3e-12
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 70 3e-12
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 70 3e-12
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 70 3e-12
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 69 5e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 69 7e-12
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 69 7e-12
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 69 9e-12
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 67 3e-11
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 65 7e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 65 7e-11
gi|148746195 trichohyalin [Homo sapiens] 65 1e-10
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 65 1e-10
>gi|41393554 LUC7-like isoform b [Homo sapiens]
Length = 371
Score = 731 bits (1886), Expect = 0.0
Identities = 371/371 (100%), Positives = 371/371 (100%)
Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT
Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS
Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS
Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR
Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
Query: 301 RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMAS 360
RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMAS
Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMAS 360
Query: 361 RRSEEKEAGEI 371
RRSEEKEAGEI
Sbjct: 361 RRSEEKEAGEI 371
>gi|8922297 LUC7-like isoform a [Homo sapiens]
Length = 325
Score = 639 bits (1647), Expect = 0.0
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT
Sbjct: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS
Sbjct: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS
Sbjct: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR
Sbjct: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
Query: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
RHRSRSRSHSRGHRRASRDRSAKYK
Sbjct: 301 RHRSRSRSHSRGHRRASRDRSAKYK 325
>gi|116812577 LUC7-like 2 [Homo sapiens]
Length = 392
Score = 540 bits (1391), Expect = e-154
Identities = 286/392 (72%), Positives = 334/392 (85%), Gaps = 21/392 (5%)
Query: 1 MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECT 60
MSAQAQMRA+LDQLMGT+RDGD TRQR+KF+DDRVCKSHLL+CCPHD+L+GTRMDLGEC
Sbjct: 1 MSAQAQMRAMLDQLMGTSRDGDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECL 60
Query: 61 KIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVS 120
K+HDLALRADYEIASKE+D FFELDAMDHL+SFIA+CDRRTE+AKKRLAETQEEISAEV+
Sbjct: 61 KVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVA 120
Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPAS 180
AKAE+VHELNEEIGKLLAK EQLGAEGNV+ESQK++ EVEK RAKK+EAEE YRNSMPAS
Sbjct: 121 AKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPAS 180
Query: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRN 240
SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI+IREKL++L++ VAEKQEKRN
Sbjct: 181 SFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRN 240
Query: 241 QDRLRRREEREREERLS-RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRH 299
Q+RL+RREEREREER RRS S +++ +RSRSR+ RR RSRS SRER++ +RS+SR++
Sbjct: 241 QERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKR 300
Query: 300 RRHRSR--SRSHSRGHRR---ASRDRS---AKYKFSRERASREE--SWESGRS--ERGPP 347
RHRSR SRS SR H+R +SRDRS +K + S+ER ++ S + RS +R P
Sbjct: 301 HRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPR 360
Query: 348 D-------WRLESSNGKMASRR-SEEKEAGEI 371
D ES+NG+ RR SEE+EAGEI
Sbjct: 361 DRDRKDKKRSYESANGRSEDRRSSEEREAGEI 392
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 212 bits (540), Expect = 4e-55
Identities = 130/375 (34%), Positives = 209/375 (55%), Gaps = 18/375 (4%)
Query: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L
Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66
Query: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ +
Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q
Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185
Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D
Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
++E++EREER R R R+ R + R + R+ RERRK SRSRSR R
Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305
Query: 301 RHRSRSRSHSRG---HRRASRDRSAKYKFSRERASREESWESGRSERGPPDWR-----LE 352
R SRSR H R RR SR R + S +R+ R+ S R R
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365
Query: 353 SSNGKMASRRSEEKE 367
S + R+S+EKE
Sbjct: 366 KSRDREQDRKSKEKE 380
Score = 63.2 bits (152), Expect = 4e-10
Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
A++ A E++ E KL + E+ + + + ++ E EK R +++E E E +
Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273
Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
++++ R E + R +D + D R E++
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323
Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ +
Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSE 343
++ +S S + S D + + K S + + E +SE
Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 212 bits (540), Expect = 4e-55
Identities = 130/375 (34%), Positives = 209/375 (55%), Gaps = 18/375 (4%)
Query: 10 LLDQLMGTARD--GDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLAL 67
LLD+LMG R+ DE R V++ + VCK +L CP ++ TR DLG C KIHD L
Sbjct: 7 LLDELMGRDRNLAPDEKRSNVRWDHESVCKYYLCGFCPAELFTNTRSDLGPCEKIHDENL 66
Query: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKA---- 123
R YE +S+ + +E D + +L+S +AE +RR RLA +Q + S+ +
Sbjct: 67 RKQYEKSSRFMKVGYERDFLRYLQSLLAEVERRIRRGHARLALSQNQQSSGAAGPTGKNE 126
Query: 124 EKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQ 183
EK+ L ++I LL + E+LG+EG V+E+Q ++ VE+++ +++E +++ + + Q
Sbjct: 127 EKIQVLTDKIDVLLQQIEELGSEGKVEEAQGMMKLVEQLK-EERELLRSTTSTIESFAAQ 185
Query: 184 QQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDR 243
++++ VCEVC A+L + D R+ DH GK H+G+ +I+ +++L++ + ++ E+ ++D
Sbjct: 186 EKQMEVCEVCGAFLIVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDE 245
Query: 244 LRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR--- 300
++E++EREER R R R+ R + R + R+ RERRK SRSRSR R
Sbjct: 246 RLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSD 305
Query: 301 RHRSRSRSHSRG---HRRASRDRSAKYKFSRERASREESWESGRSERGPPDWR-----LE 352
R SRSR H R RR SR R + S +R+ R+ S R R
Sbjct: 306 RRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRS 365
Query: 353 SSNGKMASRRSEEKE 367
S + R+S+EKE
Sbjct: 366 KSRDREQDRKSKEKE 380
Score = 63.2 bits (152), Expect = 4e-10
Identities = 57/227 (25%), Positives = 102/227 (44%), Gaps = 21/227 (9%)
Query: 117 AEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNS 176
A++ A E++ E KL + E+ + + + ++ E EK R +++E E E +
Sbjct: 221 AKIKATVEELKE------KLRKRTEEPDRDERLKKEKQEREEREKERERERE-ERERKRR 273
Query: 177 MPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQ 236
++++ R E + R +D + D R E++
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDR----------RCSRSRDHKRSRSRERR 323
Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
R++DR RR +R ER R SR+RDRRRS+SRDR+ + RS SR+R + +S+ +
Sbjct: 324 RSRSRDR-RRSRSHDRSERKHR---SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEK 379
Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSE 343
++ +S S + S D + + K S + + E +SE
Sbjct: 380 EKRGSDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 88.6 bits (218), Expect = 8e-18
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 4/114 (3%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
RE+L+ E + KR + + R R RR SR+R+R++SRSR R R++SR
Sbjct: 40 RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
S SRER+K SRSRSR+R RR RSRSRS SR HR +R RS SR+R R E
Sbjct: 98 SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRIE 149
Score = 82.0 bits (201), Expect = 8e-16
Identities = 49/102 (48%), Positives = 66/102 (64%), Gaps = 5/102 (4%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
RK+ + R++ R RR R RE + SR SR+R+R++SRSR R R++SRS SRER+
Sbjct: 58 RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 114
Query: 289 KLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK-YKFSR 328
+ RSRSR R R RHR+RSRS +R R + R K +FSR
Sbjct: 115 RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156
Score = 59.7 bits (143), Expect = 4e-09
Identities = 45/141 (31%), Positives = 67/141 (47%), Gaps = 11/141 (7%)
Query: 235 KQEKRNQDRLRRREEREREERLSRR-SGSRTRDRRRS--RSRDRRRRRSRSTSRERRKLS 291
KQ +R++ + + ++ + EE + S + R+R S DR +R+ R +SR R S
Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR---S 65
Query: 292 RSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYKFSRERASREESWESGRSERGP 346
SRSR R RRHRSRSR + R+ SR RS + K SR R+ + RS
Sbjct: 66 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 125
Query: 347 PDWRLESSNGKMASRRSEEKE 367
S + SR + K+
Sbjct: 126 RHRHRTRSRSRTRSRSRDRKK 146
Score = 57.4 bits (137), Expect = 2e-08
Identities = 49/155 (31%), Positives = 78/155 (50%), Gaps = 15/155 (9%)
Query: 161 KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQ 220
K ++ KK EE+ + +S +++L S+ G + R+ G+ H
Sbjct: 17 KDKSSKKHKSEEHNDKEHSSDKGRERLN-----SSENGEDRHKRKERKSSRGRSHS---- 67
Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR-RRSRSRDRRRRR 279
R + + R ++ K+++ R R R++ R ++S SR+R+R RR RSR R R R
Sbjct: 68 -RSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
Query: 280 SRSTSRERRKLSRSRSRDRHRR---HRSRSRSHSR 311
R +R R + +RSRSRDR +R R SRS SR
Sbjct: 127 HRHRTRSRSR-TRSRSRDRKKRIEKPRRFSRSLSR 160
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 88.6 bits (218), Expect = 8e-18
Identities = 55/114 (48%), Positives = 70/114 (61%), Gaps = 4/114 (3%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
RE+L+ E + KR + + R R RR SR+R+R++SRSR R R++SR
Sbjct: 99 RERLNSSEN--GEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
S SRER+K SRSRSR+R RR RSRSRS SR HR +R RS SR+R R E
Sbjct: 157 SRSRERKK-SRSRSRERKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKKRIE 208
Score = 80.9 bits (198), Expect = 2e-15
Identities = 50/103 (48%), Positives = 67/103 (65%), Gaps = 7/103 (6%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
RK+ + R++ R RR R RE + SR SR+R+R++SRSR R R++SRS SRER+
Sbjct: 117 RKSSRGRSHSRSRSRERRHRSRSRERKKSR---SRSRERKKSRSRSRERKKSRSRSRERK 173
Query: 289 KL--SRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK-YKFSR 328
+ SRSRSR RH RHR+RSRS +R R + R K +FSR
Sbjct: 174 RRIRSRSRSRSRH-RHRTRSRSRTRSRSRDRKKRIEKPRRFSR 215
Score = 60.5 bits (145), Expect = 2e-09
Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 11/149 (7%)
Query: 223 EKLDQLRKTVAEKQEK----RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR 278
+K +Q +V+ + K R++ R R R+ + E RS SR+++ RR S+D+ +
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSK 81
Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWE 338
+ +S ++ S + R+R + H R R++SR RS SRER R S E
Sbjct: 82 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 141
Query: 339 SGRSERGPPDWRLESSNGKMASRRSEEKE 367
+S R S K + RS E++
Sbjct: 142 RKKS-------RSRSRERKKSRSRSRERK 163
Score = 59.3 bits (142), Expect = 5e-09
Identities = 47/160 (29%), Positives = 73/160 (45%), Gaps = 21/160 (13%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRR-----------SGSRTRDRRRS--RS 272
++ RK+ E ++ R++ R + E +++ S++ S + R+R S
Sbjct: 49 ERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENG 108
Query: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYKFS 327
DR +R+ R +SR R S SRSR R RRHRSRSR + R+ SR RS + K S
Sbjct: 109 EDRHKRKERKSSRGR---SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKS 165
Query: 328 RERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
R R+ + RS S + SR + K+
Sbjct: 166 RSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
Score = 55.1 bits (131), Expect = 1e-07
Identities = 46/133 (34%), Positives = 60/133 (45%), Gaps = 27/133 (20%)
Query: 237 EKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSR 296
EK + DR +++E+ E R SRSR R R R R + E RK
Sbjct: 14 EKTSPDRDKKKEQSEVSV------SPRASKHHYSRSRSRSRERKRKSDNEGRK------- 60
Query: 297 DRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESS-N 355
HRSRSRS G R S+D+S+K S E +E S + GR RL SS N
Sbjct: 61 -----HRSRSRS-KEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRE-------RLNSSEN 107
Query: 356 GKMASRRSEEKEA 368
G+ +R E K +
Sbjct: 108 GEDRHKRKERKSS 120
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 84.7 bits (208), Expect = 1e-16
Identities = 57/148 (38%), Positives = 73/148 (49%), Gaps = 14/148 (9%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
RK A + ++ R R ++ + RRS SR RDRRR RSR R +RRSRS R+R
Sbjct: 9 RKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRL 68
Query: 289 KLSRSRSRDRHR-------RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
+ SRSR RDR R R R RSRS SRG R S K K + R+ +E + G
Sbjct: 69 RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGE 128
Query: 342 SERGPPDWRLESSNGKMASRRSEEKEAG 369
S + E K +EK+AG
Sbjct: 129 SSK-------EKKKDKDDKEDEKEKDAG 149
Score = 74.7 bits (182), Expect = 1e-13
Identities = 58/138 (42%), Positives = 69/138 (50%), Gaps = 26/138 (18%)
Query: 247 REEREREERLSRR--SGSRTRDR------------RRSRSRDRRRRRSRSTSRERRKLSR 292
RE R +R + R SGSR+R R RRSRSRDR RRR RS SR++R+ SR
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRR-SR 61
Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLE 352
SR R R RR RSR R SR RR SR R + SR R R S G +
Sbjct: 62 SRDRKRLRRSRSRERDRSR-ERRRSRSRDRRRSRSRSRGRRSRSSSPGN----------K 110
Query: 353 SSNGKMASRRSEEKEAGE 370
S + SR E+ + GE
Sbjct: 111 SKKTENRSRSKEKTDGGE 128
Score = 70.9 bits (172), Expect = 2e-12
Identities = 52/149 (34%), Positives = 78/149 (52%), Gaps = 26/149 (17%)
Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR-RRSRSTSRER- 287
++ ++K+ KR DR R +R+R RR SR+RD+RRSRSRDR+R RRSRS R+R
Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDR-----RRERSRSRDKRRSRSRDRKRLRRSRSRERDRS 79
Query: 288 ----------RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
R+ SRSRSR R RSRS S G++ + ++ S+E+ ES
Sbjct: 80 RERRRSRSRDRRRSRSRSRGR------RSRSSSPGNKSKKTENRSR---SKEKTDGGESS 130
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSEEK 366
+ + ++ + E G + EE+
Sbjct: 131 KEKKKDKDDKEDEKEKDAGNFDQNKLEEE 159
Score = 62.4 bits (150), Expect = 6e-10
Identities = 47/144 (32%), Positives = 66/144 (45%), Gaps = 3/144 (2%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRRRSRSTSRER 287
R +K+ R++DR R R R RE SR R SR+RDRRRSRSR R RR S+ +
Sbjct: 51 RSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNK 110
Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPP 347
K + +RSR + + S + + D K + ++ EE R ER
Sbjct: 111 SKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRK-RKER-VE 168
Query: 348 DWRLESSNGKMASRRSEEKEAGEI 371
WR E M + +KE E+
Sbjct: 169 KWREEQRKKAMENIGELKKEIEEM 192
Score = 37.4 bits (85), Expect = 0.022
Identities = 30/157 (19%), Positives = 62/157 (39%), Gaps = 11/157 (7%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD--------RRRSRSRDRRR 277
D+ R + +E+ RR R+R SR G R+R + +RSR + +
Sbjct: 64 DRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEK 123
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
+S+E++K + ++ + + ++ R ++R K++ + + + E
Sbjct: 124 TDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIG 183
Query: 338 ESGR---SERGPPDWRLESSNGKMASRRSEEKEAGEI 371
E + + W LE + EKE E+
Sbjct: 184 ELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEM 220
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 79.0 bits (193), Expect = 7e-15
Identities = 67/217 (30%), Positives = 96/217 (44%), Gaps = 17/217 (7%)
Query: 163 RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIR 222
R KKKE +E+ P + L E +A + + ++ R L K R
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINA-IEMEEDKRDLISREISKF-------R 285
Query: 223 EKLDQLRKTVAEKQEKRNQ-DRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
+ +L + +K+++R + ++ RR ERERE RR R R+R R R +++ R R R
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 282 STSRER-RKLSRSRSRDRHR-RHRSRSRSHSRG-----HRRASRDRSAKYKFSRER-ASR 333
R+R R R R RDR R R R R RS R R SRDR + + RER R
Sbjct: 346 ERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER 405
Query: 334 EESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
E E R + E K R +E++A E
Sbjct: 406 EREREREREREREREREREREKDKKRDREEDEEDAYE 442
Score = 69.3 bits (168), Expect = 5e-12
Identities = 67/272 (24%), Positives = 114/272 (41%), Gaps = 25/272 (9%)
Query: 88 DHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE--------KVHELNEEIGK---- 135
D E+ E RR ++ K + E S+E++A ++ K E E+I +
Sbjct: 191 DDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPV 250
Query: 136 -------LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLR 188
L+ K + E D+ I E+ K R K+ EEE +++ R
Sbjct: 251 APLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERR 310
Query: 189 VCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRRE 248
E + +RR + + + + ++ R ++ ++R++DR R R+
Sbjct: 311 ERERERE----RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERD 366
Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRHR-RHRSRS 306
ER S R+ R+R R +SR R+R R R R RER R+ R R R+R R R R R
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 307 RSHSRGHRRASRDRSAKYKFSRERASREESWE 338
+ R D + K R+ +E +++
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQ 458
Score = 64.3 bits (155), Expect = 2e-10
Identities = 65/262 (24%), Positives = 113/262 (43%), Gaps = 32/262 (12%)
Query: 111 TQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAE 170
T+E+I+A + + +K ++ EI K ++L E E ++ +E E+ R +++E E
Sbjct: 260 TKEDINA-IEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKER-RERERERE 317
Query: 171 EEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRK 230
E ++++ R E D DR D+ ++
Sbjct: 318 RERERREREREREREREREKEKERERERERDRDR---------------------DRTKE 356
Query: 231 TVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKL 290
++ +R++DR R R ++R RS ++RDR R R R+R R R R RER +
Sbjct: 357 RDRDRDRERDRDRDRERSSDRNKDR--SRSREKSRDRERERERERERERERERERERER- 413
Query: 291 SRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE---SWESGRSERGP 346
R R R+R R R + + R A R + K + A+ +E +WE R +
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEI-RERKKT 472
Query: 347 PDWRLESSNGKMASRRSEEKEA 368
++ E+ + RR KEA
Sbjct: 473 REYEKEAER-EEERRREMAKEA 493
Score = 56.6 bits (135), Expect = 3e-08
Identities = 60/273 (21%), Positives = 112/273 (41%), Gaps = 23/273 (8%)
Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEA 169
+ ++ IS E+S + +L EE GK + +++ E E ++ E E+ R +++
Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERER---ERERERRERERE 328
Query: 170 EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR---------RLADHFGGKLHLGFIQ 220
E R ++++ R + D DR R +D + +
Sbjct: 329 REREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRS-----R 383
Query: 221 IREKL---DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
REK ++ R+ E++ +R ++R R RE ER R + RDR R
Sbjct: 384 SREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
R+ RE+ + R ++ R R ++R + + A R+ + + ++E +E
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRERKKTREY---EKEAEREEERRREMAKEAKRLKEFL 500
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
E +R P + S+ K R +E EA E
Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADE 533
Score = 32.7 bits (73), Expect = 0.54
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 37/157 (23%)
Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREE-RLSRRSGSRTRDRRRSRSRDRRRRRS----- 280
+L + + EK E Q+RL+ E RER++ R + R +RRR +++ +R +
Sbjct: 445 KLERKLREK-EAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDY 503
Query: 281 ---------------RSTSRERRKLSRSRSRDRHRRHRS----RSRSHSRGH-------- 313
+ R+R K + RDR R R R + GH
Sbjct: 504 DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQ 563
Query: 314 ---RRASRDRSAKYKFSRERASREESWESGRSERGPP 347
+ A R R + K E EE + +R P
Sbjct: 564 RMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEP 600
Score = 28.9 bits (63), Expect = 7.8
Identities = 20/99 (20%), Positives = 44/99 (44%), Gaps = 8/99 (8%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--------EQLGAEGNVDE 151
R +KRL + ++E+ A+ + + EL E +LLA+ +++ E
Sbjct: 514 RGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR 573
Query: 152 SQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVC 190
+I E E ++++ E+E + P ++ + + C
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 76.3 bits (186), Expect = 4e-14
Identities = 86/312 (27%), Positives = 143/312 (45%), Gaps = 41/312 (13%)
Query: 70 DYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHEL 129
D++ SKERD+ + D ++ + KKR S E S E+ +
Sbjct: 428 DHKSNSKERDIRRNSEKDDKYKNKV----------KKRAKSKSRSKSKEKSKSKERDSKH 477
Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKIL----MEVEKVRAKKKEAEEEYRNSMPASSFQQQ 185
N K + + NV E +K + E+ R+K+K + E +++ S ++
Sbjct: 478 NRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKE 537
Query: 186 KLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR 245
K R + S R D GK H + RE+ ++ + ++DR R
Sbjct: 538 KDRRAQSRS----------RECDITKGK-HSYNSRTRERSRSRDRSRRVRSRTHDRDRSR 586
Query: 246 RRE-EREREERLSRRSGSRTRDRR----RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR 300
+E R RE+ RR SR+R+RR RSRS+DRRRRR S S ER + S+SR++D++R
Sbjct: 587 SKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREE-SQSRNKDKYR 645
Query: 301 RHRSRS---RSHSRGHRR---ASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESS 354
S+S + +S +R SRD ++ ++A R++S + ++ D L+SS
Sbjct: 646 NQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQS-PFSKIKQSSQDNELKSS 704
Query: 355 NGKMASRRSEEK 366
M + +EK
Sbjct: 705 ---MLKNKEDEK 713
Score = 70.1 bits (170), Expect = 3e-12
Identities = 77/297 (25%), Positives = 131/297 (44%), Gaps = 27/297 (9%)
Query: 94 IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
I E R K+R +S + K EK ++ + K +K + D+
Sbjct: 391 IKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDH--KSNSKERDIRRNSEKDDKY 448
Query: 154 KILMEVE---KVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHF 210
K ++ K R+K KE + + +++++R + + + +++ +D
Sbjct: 449 KNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQ-SDSK 507
Query: 211 GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGS-RTRDRRR 269
G + +EK QL E +++++ RR + R RE +++ S +R R R
Sbjct: 508 GKDQERS--RSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRER 565
Query: 270 SRSRDRRRR-RSRSTSRER---RKLSRSRSRDRHRRHRSRS--------RSHSRGHRRAS 317
SRSRDR RR RSR+ R+R ++ R R ++ RR RSRS RS S+ RR
Sbjct: 566 SRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRR 625
Query: 318 RD-----RSAKYKFSRERASREESWESGRSERGPPDWRLES-SNGKMASRRSEEKEA 368
RD R ++++ +ES S R E + R+ S S +S S EK+A
Sbjct: 626 RDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKA 682
Score = 55.5 bits (132), Expect = 8e-08
Identities = 43/140 (30%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR---RSRSTSRERRKLS 291
K++++ D + +ER R + S++ S++ + S+S+++ RR RSR + K S
Sbjct: 498 KEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHS 557
Query: 292 -RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWR 350
SR+R+R R R SR H R R RS +Y RE+ R R R PP R
Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDR-DRSRSKEYHRYREQEYRRRGRSRSRERRTPPG-R 615
Query: 351 LESSNGKMASRRSEEKEAGE 370
S + + R S E E
Sbjct: 616 SRSKDRRRRRRDSRSSEREE 635
Score = 38.5 bits (88), Expect = 0.010
Identities = 40/150 (26%), Positives = 60/150 (40%), Gaps = 11/150 (7%)
Query: 228 LRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR----TRDRRRSRSRDRRRRR--SR 281
+RK+ + EK ++R R RE S R TR R+ + R RR R SR
Sbjct: 287 MRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSR 346
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERAS----REESW 337
S SR+R + S + R R++ S G R D+S + + S +E
Sbjct: 347 SRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKI 406
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSEEKE 367
R+ P+ R K+ +S KE
Sbjct: 407 TDHRNVSESPN-RKNEKEKKVKDHKSNSKE 435
Score = 37.7 bits (86), Expect = 0.017
Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 48/174 (27%)
Query: 239 RNQDRLRR-------REEREREERL---------------------SRRSGSRTRDRR-- 268
R++DR RR R+E +R +R+ ++RS R ++R+
Sbjct: 348 RSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKIT 407
Query: 269 ----------RSRSRDRRRRRSRSTSRERRKLSRSRSRDRH-----RRHRSRSRSHSRGH 313
R ++++ + +S S+ER S D++ +R +S+SRS S+
Sbjct: 408 DHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK-E 466
Query: 314 RRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
+ S++R +K+ + E+ R S GR + +S + RS KE
Sbjct: 467 KSKSKERDSKHNRNEEKRMRSRS--KGRDHENVKEKEKQSDSKGKDQERSRSKE 518
Score = 37.0 bits (84), Expect = 0.028
Identities = 23/102 (22%), Positives = 44/102 (43%), Gaps = 6/102 (5%)
Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305
++EE++R + S S S + S S+ S S S + + +S+ R ++HR
Sbjct: 184 KKEEKKRHKSSSSSSSSSSDSDSSSDSQ------SSSDSSDSESATEEKSKKRKKKHRKN 237
Query: 306 SRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPP 347
SR H + ++ + + + S + + R E PP
Sbjct: 238 SRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP 279
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 75.1 bits (183), Expect = 9e-14
Identities = 75/287 (26%), Positives = 125/287 (43%), Gaps = 42/287 (14%)
Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
E +R E + R + Q E + A+ E+ + + E + + Q E + ++
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
E+ R ++KE + E R+S ++++ E +R D
Sbjct: 190 ----ERERQREKENKTEDRHSERGRERERERETETET---------ERKRQTD------- 229
Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS----- 270
RE+ D+ RKT E++++ ++R RE +ER R R RDRR+
Sbjct: 230 ------RER-DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 271 --RSRDRRRRRSRSTSRER-RKLSRSRSRDRHR-RHRSRSRSHSRGHRR-ASRDRSAKYK 325
R R RR R R T R+R R+ R R R+R+R R R R R R +R RDR + +
Sbjct: 283 TDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERE 342
Query: 326 FSRERAS---REESWESGRSER--GPPDWRLESSNGKMASRRSEEKE 367
R+R + RE + ++GR R + E + ++R EE+E
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERE 389
Score = 69.3 bits (168), Expect = 5e-12
Identities = 63/268 (23%), Positives = 107/268 (39%), Gaps = 10/268 (3%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
DR E + R E + + E + EK +E + + + G + D +
Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR---- 147
Query: 158 EVEKVRAKKKEAEEEY-RNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
E E+ R +KE E + R + +QK R E + R + K
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKEN----KTED 203
Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
+ + ++ R+T E + KR DR R R+ + ER + R +R R ++R
Sbjct: 204 RHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREES 336
R R R R+RR+ R R DR R+ R+ + R R+R + + +R+R RE
Sbjct: 264 RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR-ERERE 322
Query: 337 WESGRSERGPPDWRLESSNGKMASRRSE 364
E R + + E + R++E
Sbjct: 323 RERERERQRETERDREKERERKRKRQTE 350
Score = 66.2 bits (160), Expect = 4e-11
Identities = 46/147 (31%), Positives = 73/147 (49%), Gaps = 9/147 (6%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRRE---EREREERLSR-RSGSRTRDRRRSRSRDRRR 277
REK R+T +++ +R +DR R+R+ ER+R+ R R R RDR+R + R+R++
Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
R R T RE + R R D R + + R+ R+R + + +R+ +E
Sbjct: 126 ERERETEREGER-GRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ---KERER 181
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSE 364
E R ER + + E N K R SE
Sbjct: 182 EKNRQERRERERQREKEN-KTEDRHSE 207
Score = 65.5 bits (158), Expect = 7e-11
Identities = 45/147 (30%), Positives = 67/147 (45%), Gaps = 16/147 (10%)
Query: 234 EKQEKRNQDRLRRREERERE-------ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
+++ R ++R RRRE+R+ E ER + R RDR R R RDR + R R T RE
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112
Query: 287 RRKLSRSRSRDRHR---RHRSRSRSHSRGHRR---ASRDRSAKYKFSRERASREESWESG 340
R R R ++R+R R R R RG R R+R + +ER + +
Sbjct: 113 R---DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 341 RSERGPPDWRLESSNGKMASRRSEEKE 367
++ER R N + R ++E
Sbjct: 170 QTERNRQKEREREKNRQERRERERQRE 196
Score = 65.5 bits (158), Expect = 7e-11
Identities = 69/293 (23%), Positives = 116/293 (39%), Gaps = 36/293 (12%)
Query: 98 DRRTELAKKRLAET---------QEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGN 148
+R TE K+R E Q+E + K ++ E + E + + + E
Sbjct: 253 ERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERE 312
Query: 149 VDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLAD 208
+ ++ E E+ R +++E E + +Q ++ DR
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEM---------------DRERNR 357
Query: 209 HFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR 268
G + + RE+ + + A ++E+R +DR R R++ + R G R +++
Sbjct: 358 QTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ 417
Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR-----HRSRSRSHSRGHRRASRDRSAK 323
R R +DR R R RER K + R RDR R+ R R RS + RS
Sbjct: 418 REREKDRESERGRERGREREK-QKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGV 476
Query: 324 YKFSRERASREESWES------GRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
+ R +R W+S S R P ++S G++A RR E GE
Sbjct: 477 VQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGE 529
Score = 64.7 bits (156), Expect = 1e-10
Identities = 51/159 (32%), Positives = 79/159 (49%), Gaps = 16/159 (10%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------RSRSRDR 275
REK ++ R+T E+ +R ++R R++ERERE + R G R RDR+ R R RD
Sbjct: 101 REK-ERERQTDRERDRQREKER-NRQKERERE---TEREGERGRDRQTDGQRERERQRDA 155
Query: 276 RRRRSRSTSRER-RKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYKFSRERA 331
+ R R T RER R+ R+R ++R R R R R R + DR ++ RER
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERER- 214
Query: 332 SREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
RE E+ R + + + + +++E + A E
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 63.9 bits (154), Expect = 2e-10
Identities = 74/296 (25%), Positives = 123/296 (41%), Gaps = 30/296 (10%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELN---EEIGKLLAKAEQLGAEGNVDESQK 154
+R+ + + R E + E + + + E+ E E+ + + E + +K
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 155 ILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKL 214
+ E+ R +K E E E + +S +++ R E D DRR +
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERAS-ERETERDKERERERDRDRDRDRRQKERERQTD 284
Query: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRD 274
+ + RK +++ +R ++R R+RE ER R RDR + R R
Sbjct: 285 RKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 275 RRRR------RSRSTSRE-RRKLSRSRSRDRHR------------RHRSRSRSHSRGHRR 315
R+R+ R+R T RE RR+ R R R+R R R R R R R R+
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER-ERQ 403
Query: 316 ASRDRSAKYKFSRERASREESWESGRS-ERGPPDWRLESSNGKMASR-RSEEKEAG 369
+DR + + ++R RE+ ES R ERG E G+ R R +++AG
Sbjct: 404 TEKDRDGQRETEKQR-EREKDRESERGRERGR---EREKQKGRERDRERQTDRQAG 455
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/152 (27%), Positives = 63/152 (41%), Gaps = 13/152 (8%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER- 287
R+ + + + + D R ++ERE R +R R DR+R R R++ R R R RER
Sbjct: 39 RRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ 98
Query: 288 --RKLSRSRSRDRHR---RHRSRSRSHSR-------GHRRASRDRSAKYKFSRERASREE 335
R+ R R DR R R + R+R R G R R + + R+R + +E
Sbjct: 99 RDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKE 158
Query: 336 SWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
ER R + R E +E
Sbjct: 159 RERQTDRERQRQTERNRQKEREREKNRQERRE 190
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 14/162 (8%)
Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
Q + D+ R+ EK R +DR R R+ +ER + R R R + R+R + R R
Sbjct: 70 QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129
Query: 280 SRSTSRER---RKLSRSRSRDRHR-----RHRSRSRSHSR---GHRRASRDRSAKYKFSR 328
ER R+ R R+R R R R R R +R+ R+R + R
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERR 189
Query: 329 ER---ASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
ER +E E SERG R + + +R ++E
Sbjct: 190 ERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Score = 57.4 bits (137), Expect = 2e-08
Identities = 43/150 (28%), Positives = 77/150 (51%), Gaps = 11/150 (7%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRRE---ERERE-ERLSRRSGSRTRDRRRSRSRDRRR 277
REK ++ R+ E++ +R +R R R+ +RERE +R + + R DR R R +R R
Sbjct: 117 REK-ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNR 175
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
++ R + R++ R R R R + +++ R RG R R+R + + R+R + E
Sbjct: 176 QKEREREKNRQE-RRERERQREKENKTEDRHSERGRER-ERERETETETERKRQTDRERD 233
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSEEKE 367
++ER R + + + AS R E++
Sbjct: 234 RQRKTERE----REKQAERERASERETERD 259
Score = 49.3 bits (116), Expect = 6e-06
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 20/155 (12%)
Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
++++ LD R+ ++ R + + ++ + ++R R R + R RR
Sbjct: 17 WVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDR------ERNRQKER-----ERR 65
Query: 278 RRSRSTSRER-RKLSRSRSRDRHR---RHRSRSRSHSR-GHRRASRDRSAKYKFSRERAS 332
R R T RE RK R R +DRHR RHR R R + R+ R+R + + R R
Sbjct: 66 REKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQK 125
Query: 333 REESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
E ERG R ++G+ R + E
Sbjct: 126 ERERETEREGERG----RDRQTDGQRERERQRDAE 156
Score = 35.4 bits (80), Expect = 0.083
Identities = 31/110 (28%), Positives = 43/110 (39%), Gaps = 7/110 (6%)
Query: 267 RRRSRSRDRRRRRSRSTS-RERRKLSRSRSRDRHRRHRSRSRSHSR-----GHRRASRDR 320
RRR S++ RRR + ++ R R+R + R R R R RR +DR
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 321 SAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
K RER R+ E R D + E + R E + GE
Sbjct: 88 HRKRDRHRER-QRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 73.9 bits (180), Expect = 2e-13
Identities = 79/309 (25%), Positives = 136/309 (44%), Gaps = 38/309 (12%)
Query: 90 LESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNV 149
L SF+ + + + L + Q+ I ++ + K+ + +E AE++
Sbjct: 204 LRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKE------GAEEIDRHVER 257
Query: 150 DESQKILMEVEKVRA-KKKEAEEEYRNSMPASSFQQQKLRVCEV--CSAYLGLHDNDRRL 206
S+ + R+ ++ + +R +SSF ++ R E + +RR
Sbjct: 258 RRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRR 317
Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-----RSG 261
+ L + RE+ ++ K ++R++DR R +E ER R R R
Sbjct: 318 SRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR-EREKENERGRRRDRDYDKERGN 376
Query: 262 SRTRDRRRSRSR--------------------DRRRRRSRSTSRERRKLSRSRSRDRHRR 301
R ++R RSR R DRR R + S++ +K SRSRSR+R R
Sbjct: 377 EREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHR 436
Query: 302 HRSRSRSHSRGHRRASRDRSAKYK-FSRERAS-REESWESGRSERGPPDWRLESSNGKMA 359
RSRSR+ + R S+++S+K+K S+E+++ R S GR++ + E S K
Sbjct: 437 SRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEK 496
Query: 360 SR-RSEEKE 367
SR RS KE
Sbjct: 497 SRKRSRSKE 505
Score = 62.8 bits (151), Expect = 5e-10
Identities = 46/154 (29%), Positives = 83/154 (53%), Gaps = 11/154 (7%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR-RSRSRDRRR-RR 279
R K + R V EK+ K ++D R R+++ ++ + S SR+R+R+ RSRSR R +R
Sbjct: 388 RSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKR 447
Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRG-----HRRASRDRSAKYKFSRERA-SR 333
SRS S+E+ ++ S+++ + RSRS S+G + R+ S + SR+R+ S+
Sbjct: 448 SRSRSKEKSSKHKNESKEKSNK---RSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504
Query: 334 EESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
E S + S+ + + + + S+EK+
Sbjct: 505 ERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Score = 38.5 bits (88), Expect = 0.010
Identities = 43/218 (19%), Positives = 90/218 (41%), Gaps = 32/218 (14%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ-KIL 156
DR E +R + E + EK E + E ++++ + G V+E + K
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRE------RSKEQRSRGEVEEKKHKED 406
Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
+ + R K+++++E ++S S ++ + R S G R
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSR---SRNAGKRSRSRS----------- 452
Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREE-----REREERLSR-RSGSRTRDRRRS 270
+EK + + EK KR++ + R + ++RE S+ +S R+R + RS
Sbjct: 453 -----KEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERS 507
Query: 271 RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308
RD + +S +RR+ + ++H+++ +
Sbjct: 508 HKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDET 545
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 73.9 bits (180), Expect = 2e-13
Identities = 86/353 (24%), Positives = 142/353 (40%), Gaps = 30/353 (8%)
Query: 19 RDGDETRQRVKFTDDRVCKS--HLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASK 76
RD +TR R + D R + + D + D HD R + K
Sbjct: 459 RDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRK 518
Query: 77 ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAE-KVHELNEEIGK 135
E D + E ++ + + + E RTE+ + E++ EI + ++ +V EL E+ G
Sbjct: 519 E-DTYPE-ESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEK-GS 575
Query: 136 LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
++ Q+ + + + + E + R+ SSF+++
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFERR---------- 625
Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER 255
H R + + I+ + + D+L + E++E+R DR+ R + ER
Sbjct: 626 ----HGERDRRDNRERDQRPSSPIRHQGRNDELERD--ERREERRVDRVDDRRDERARER 679
Query: 256 LSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHR 314
R R R+R R R RDR R + R RER + R R R++ R R R R R H R R
Sbjct: 680 DRERERDRERERERERERDREREKERELERERAR-EREREREKERDRERDRDRDHDR-ER 737
Query: 315 RASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
R+R + + RER RE E R R + A R +E+E
Sbjct: 738 ERERERDREKEREREREERERERERERERE-----RERERERERARERDKERE 785
Score = 64.3 bits (155), Expect = 2e-10
Identities = 46/136 (33%), Positives = 63/136 (46%), Gaps = 13/136 (9%)
Query: 229 RKTVAEKQEKRNQDRLRRRE-EREREERLSR---RSGSRTRDRRRSRSRDRRRRRSRSTS 284
R+ E++++R +R R RE ERERE+ R R R+R R R RDR + R R
Sbjct: 695 RERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERERERE 754
Query: 285 RERRKLSRSRSRDRHR---RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
R+ R R R+R R R R+R R R +R D+ + R R E E R
Sbjct: 755 ERERERERERERERERERERERARERDKERERQRDWEDK------DKGRDDRREKREEIR 808
Query: 342 SERGPPDWRLESSNGK 357
+R P D E + K
Sbjct: 809 EDRNPRDGHDERKSKK 824
Score = 60.1 bits (144), Expect = 3e-09
Identities = 44/139 (31%), Positives = 62/139 (44%), Gaps = 6/139 (4%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285
D+ R E++ +R +DR + RE REREER R R R+R R R R+R R R R R
Sbjct: 728 DRDRDHDRERERERERDREKERE-REREER--ERERERERERERERERERERARERDKER 784
Query: 286 ERRK--LSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSE 343
ER++ + + RD R R R R R +R +K ++ E + R E
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIR-EDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRRE 843
Query: 344 RGPPDWRLESSNGKMASRR 362
P S + K R
Sbjct: 844 HSPDSDAYNSGDDKNEKHR 862
Score = 59.7 bits (143), Expect = 4e-09
Identities = 45/146 (30%), Positives = 62/146 (42%), Gaps = 11/146 (7%)
Query: 229 RKTVAEKQEKRNQDRLR-------RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
R+ EK+ R +DR R R ER+RE+ R R R+R R R R+R R R R
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERER 774
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASR-DRSAKYKFSRERASREESWESG 340
+RER K R R R + + R R R R DR+ + ++ + E
Sbjct: 775 ERARERDK---ERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGS 831
Query: 341 RSERGPPDWRLESSNGKMASRRSEEK 366
S R P R E S A ++K
Sbjct: 832 PSPRQSPKRRREHSPDSDAYNSGDDK 857
Score = 52.8 bits (125), Expect = 5e-07
Identities = 52/186 (27%), Positives = 74/186 (39%), Gaps = 24/186 (12%)
Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-RREEREREERL 256
G HD++R H + H R K D+ + + E++ +++Q R R++RE +
Sbjct: 399 GRHDHERTSQSH--DRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 257 SRRSGSRTRDRRRSR--------------SRDRRRRRSRSTSRERRKLSRSRSRDRHRRH 302
RR TRDRR R SRD + R SR R R R+ H
Sbjct: 457 DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH 516
Query: 303 RSR------SRSHSRGHRRASRDRSAKYKFSR-ERASREESWESGRSERGPPDWRLESSN 355
R SRS+ R H R R+ SR E S + GRS P+ + S
Sbjct: 517 RKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Query: 356 GKMASR 361
G S+
Sbjct: 577 GSRGSQ 582
Score = 49.3 bits (116), Expect = 6e-06
Identities = 45/144 (31%), Positives = 64/144 (44%), Gaps = 10/144 (6%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGS----RTRDRRRSRSRDRRRRRS--RSTSRER 287
+++++ DR R RE R+ +R R R RDR R R R+R R R R RER
Sbjct: 1300 QERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRER 1359
Query: 288 RKL-SRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGP 346
+L S S RD R R R R+ + + AK + ER S +S ++
Sbjct: 1360 ERLISDSVERD---RDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKER 1416
Query: 347 PDWRLESSNGKMASRRSEEKEAGE 370
D L S G + +SE E+ E
Sbjct: 1417 MDKDLGSVQGFEETNKSERTESLE 1440
Score = 47.0 bits (110), Expect = 3e-05
Identities = 46/141 (32%), Positives = 67/141 (47%), Gaps = 22/141 (15%)
Query: 222 REKLDQL------RKTVAEKQEKRNQDRLRRREEREREERLSRRSGS-------RTRDR- 267
+ ++DQL R T +++Q+ R+ RR E + ++ RSGS + RDR
Sbjct: 1248 KSRIDQLKRGEPSRSTSSDRQDSRSHSS--RRSSPESDRQVHSRSGSFDSRDRLQERDRY 1305
Query: 268 --RRSRSRDRRRRRSRSTSRERRK-LSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAK 323
R R R+RR R R R+ K R+R RDR R R R R R R R R+R
Sbjct: 1306 EHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDR-ERERLIS 1364
Query: 324 YKFSRER-ASREESWESGRSE 343
R+R R+ ++ES + E
Sbjct: 1365 DSVERDRDRDRDRTFESSQIE 1385
Score = 46.2 bits (108), Expect = 5e-05
Identities = 48/149 (32%), Positives = 64/149 (42%), Gaps = 11/149 (7%)
Query: 200 HDNDRRLADHFGGK---LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256
+D+ R D G+ LH G + REK L T + K D+L+R E
Sbjct: 1211 NDSAHRSGDDQSGRKRVLHSGS-RDREKTKSLEIT---GERKSRIDQLKRGEPSRSTS-- 1264
Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316
S R SR+ RRS R+ SRS S + R + R R H R R R R +R R
Sbjct: 1265 SDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTR-QREW 1323
Query: 317 SRDRSAKYKFSRER-ASREESWESGRSER 344
RD + +R+R RE E R +R
Sbjct: 1324 DRDADKDWPRNRDRDRLRERERERERDKR 1352
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/114 (32%), Positives = 48/114 (42%), Gaps = 7/114 (6%)
Query: 233 AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
A+K RN+DR R RE ER RR R R+R S S +R R R R R
Sbjct: 1327 ADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRD-----RTFES 1381
Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRSA--KYKFSRERASREESWESGRSER 344
S+ R H R SRD A K + ++ S + E+ +SER
Sbjct: 1382 SQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSER 1435
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 4/117 (3%)
Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRST-SRERRKLSRSRSR 296
+R Q R R + R S++ DRR R D R +R R SRE R+ + +S
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSS 442
Query: 297 DR-HRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASRE--ESWESGRSERGPPDWR 350
R HR R R R +RDR R SRE + + R P D R
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSR 499
Score = 41.2 bits (95), Expect = 0.002
Identities = 64/275 (23%), Positives = 108/275 (39%), Gaps = 43/275 (15%)
Query: 77 ERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKL 136
ERD E +D ++ E R + ++R E + E E + EK EL E +
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARE 714
Query: 137 LAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAY 196
+ + + D + E E+ R + +E E E ++++ R E
Sbjct: 715 REREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERE----- 769
Query: 197 LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL 256
+ +R A R+K ++ R+ E ++K DR +REE RE+R
Sbjct: 770 ---RERERERARE------------RDK-ERERQRDWEDKDKGRDDRREKREEI-REDRN 812
Query: 257 SRRSGSRTRDRRRSRSRDRRR--RRSRSTSRERRKLS-----RSRSRDRHRRHR------ 303
R D R+S+ R R R + + RR+ S + D++ +HR
Sbjct: 813 PRDG----HDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVV 868
Query: 304 --SRSRSHSRGHRRASRDRSAKYKFSRERASREES 336
SRS S H + DR ++K + R+ES
Sbjct: 869 RPQESRSLSPSH--LTEDRQGRWKEEDRKPERKES 901
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/187 (27%), Positives = 73/187 (39%), Gaps = 47/187 (25%)
Query: 223 EKLDQLRKTVAEKQEKRNQDRLR-------RREEREREERL-------SRRSGSRTRDRR 268
EK++ T+ + Q ++ D+ R R RL + RSG R+
Sbjct: 1166 EKVETPHVTIEDAQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRK 1225
Query: 269 R---SRSRDRRR---------RRSRSTSRERRKLSRSRSRDRH--RRHRSRSRS------ 308
R S SRDR + R+SR +R + SRS S DR R H SR S
Sbjct: 1226 RVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQ 1285
Query: 309 -HSRGHRRASRDR---SAKYKFSRERA-----SREESWESGRSERGPPDWRLESSNGKMA 359
HSR SRDR +Y+ RER +R+ W+ + DW ++
Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADK----DWPRNRDRDRLR 1341
Query: 360 SRRSEEK 366
R E +
Sbjct: 1342 ERERERE 1348
Score = 40.4 bits (93), Expect = 0.003
Identities = 74/317 (23%), Positives = 116/317 (36%), Gaps = 81/317 (25%)
Query: 110 ETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEG-NVDESQKILMEVEK----VRA 164
ET + S + VHEL+ E+ + + E + E N+++ ++I+++ E VR+
Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEIIIKKEVSPEVVRS 204
Query: 165 K-------KKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRL----------- 206
K +K ++ R S P SS +K R S+ L + +
Sbjct: 205 KLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP 264
Query: 207 -------ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERERE------ 253
D GK + ++++++++ KT K R+ +R R + ++ R
Sbjct: 265 SPPPPIPEDIALGKKYKEKYKVKDRIEE--KTRDGKDRGRDFERQREKRDKPRSTSPAGQ 322
Query: 254 -----------------ERLSRRSGSRTRDRRRSRSRDR------RRRRSRSTSRERRKL 290
+ R S S R R S S R RR S S
Sbjct: 323 HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSP 382
Query: 291 SRSRSRDRHRR---------HRSRSRSHSRGHRRASRDRSAKYKFSRERASREE------ 335
R +S RHR H S+SH R H R R K RE+ SREE
Sbjct: 383 QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRG---KRDREKDSREEREYEQD 439
Query: 336 --SWESGRSERGPPDWR 350
S R +R P D R
Sbjct: 440 QSSSRDHRDDREPRDGR 456
Score = 39.3 bits (90), Expect = 0.006
Identities = 43/154 (27%), Positives = 63/154 (40%), Gaps = 8/154 (5%)
Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
+REK + ++ ++R++ R R +R+RE+ SR R ++ +S SRD R R
Sbjct: 395 MREKGRHDHERTSQSHDRRHERREDTRGKRDREKD-SREE--REYEQDQSSSRDHRDDRE 451
Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE---SW 337
R+RR +RDR SR SR R SRD R++R+
Sbjct: 452 PRDGRDRR--DARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRD 509
Query: 338 ESGRSERGPPDWRLESSNGKMASRRSEEKEAGEI 371
GR D E S + EE EI
Sbjct: 510 REGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Score = 29.3 bits (64), Expect = 5.9
Identities = 30/160 (18%), Positives = 65/160 (40%), Gaps = 21/160 (13%)
Query: 220 QIREKLDQLRKT-----VAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRD 274
+++EK+ + K + E R QD + + +RE S R+ + + + + +
Sbjct: 909 ELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRET--SDRAHDENKKKAKIQKKP 966
Query: 275 RRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASRE 334
++++ ER + + S D + S +G ++ S ++ K S E
Sbjct: 967 IKKKKEDDVGIERGNIETT-SED------GQVFSPKKGQKKKSIEKKRKKSKGDSDISDE 1019
Query: 335 ESWESGRSERGP-------PDWRLESSNGKMASRRSEEKE 367
E+ + + +RGP + +E NGK +K+
Sbjct: 1020 EAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKK 1059
>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
sapiens]
Length = 437
Score = 73.2 bits (178), Expect = 4e-13
Identities = 49/111 (44%), Positives = 62/111 (55%), Gaps = 11/111 (9%)
Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDR 298
R++DR R RE RER R + R+RRRSRSRDRRRR SRS +E R+ SR RS+D
Sbjct: 231 RDRDRDRERERRERS-----RERDKERERRRSRSRDRRRR-SRSRDKEERRRSRERSKD- 283
Query: 299 HRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRS--ERGPP 347
+ R R R SR RA R+R K + E E+G + + GPP
Sbjct: 284 --KDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPP 332
Score = 67.8 bits (164), Expect = 2e-11
Identities = 48/118 (40%), Positives = 60/118 (50%), Gaps = 12/118 (10%)
Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRR---SRSRDRRRRRSRSTSRERRKLSRSRSRD 297
+D R +ER L R R R+R R SR RD+ R R RS SR+RR+ RSRSRD
Sbjct: 213 RDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRR--RSRSRD 270
Query: 298 RHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESG-----RSERG--PPD 348
+ R RSR RS + R R ++ + RER +EE G SE G PPD
Sbjct: 271 KEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPD 328
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/172 (28%), Positives = 68/172 (39%), Gaps = 47/172 (27%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
RE+ ++ R+ E++ +R++ R RRR R R++ RRS R+R + + RDR+RR SR
Sbjct: 239 RERRERSRERDKERERRRSRSRDRRRRSRSRDKEERRRS----RERSKDKDRDRKRRSSR 294
Query: 282 STSRERRKLSR-----------------------------------------SRSRDRHR 300
S R RR+ R R RDR R
Sbjct: 295 SRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRER 354
Query: 301 RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLE 352
R RS R R RDR ++K R E + R G D LE
Sbjct: 355 RRSHRSERERRRDRDRDRDRDREHK--RGERGSERGRDEARGGGGGQDNGLE 404
Score = 54.3 bits (129), Expect = 2e-07
Identities = 48/131 (36%), Positives = 58/131 (44%), Gaps = 12/131 (9%)
Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRR---- 301
RR + R S R + D R S R R R RERR+ SR R ++R RR
Sbjct: 200 RRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRS 259
Query: 302 --HRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMA 359
R RSRS + RR SR+RS R+R S S E R ER + L G MA
Sbjct: 260 RDRRRRSRSRDKEERRRSRERSKDKDRDRKRRS-SRSRERARRERERKE-ELRGGGGDMA 317
Query: 360 SRRSEEKEAGE 370
E EAG+
Sbjct: 318 ----EPSEAGD 324
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/112 (33%), Positives = 52/112 (46%), Gaps = 5/112 (4%)
Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA 316
+RR G+ R R D R R R R R+R RR RSR R R RR+
Sbjct: 199 TRRGGADVNIRHSGRD-DTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRS 257
Query: 317 -SRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
SRDR + + SR++ R S E RS+ D + SS + +RR E++
Sbjct: 258 RSRDRRRRSR-SRDKEERRRSRE--RSKDKDRDRKRRSSRSRERARRERERK 306
Score = 33.9 bits (76), Expect = 0.24
Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 249 EREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRS 308
+R+RE R S RS R+RRR R RDR R R +R + R RD R +
Sbjct: 349 DRDRERRRSHRS---ERERRRDRDRDRDRDR----EHKRGERGSERGRDEARGGGGGQDN 401
Query: 309 HSRGHRRASRD 319
G SRD
Sbjct: 402 GLEGLGNDSRD 412
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 73.2 bits (178), Expect = 4e-13
Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 18/147 (12%)
Query: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
++ +D L++ A Q++ R E R+R ++ R SR+RDR R R RDR R R
Sbjct: 139 VKVAVDVLKELEALMPSAAGQEKQRDAEHRDRTKKKKR---SRSRDRNRDRDRDRERNRD 195
Query: 281 RSTSRERRKLSRSRSRDRHR-----RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
R R R SRSRSR R R R+RSRSRS S R RD+ + R
Sbjct: 196 RDHKRRHRSRSRSRSRTRERNKVKSRYRSRSRSQSPPKDRKDRDKYGERNLDR------- 248
Query: 336 SWESGRSERGPPDWRL--ESSNGKMAS 360
W +R PP+ + NGK+ S
Sbjct: 249 -WRDKHVDRPPPEEPTIGDIYNGKVTS 274
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/136 (37%), Positives = 68/136 (50%), Gaps = 7/136 (5%)
Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287
K+ + R++ R RRR R R + RRS S+ + +R + RS+ R R+R RS+SR+
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914
Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPP 347
RK R+RSR RR RS + S R R R RS + S R SR S S R
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS--FSISPSRRSRTPSRRSRTPSRRS- 1971
Query: 348 DWRLESSNGKMASRRS 363
R S + SRRS
Sbjct: 1972 --RTPSRRSRTPSRRS 1985
Score = 70.1 bits (170), Expect = 3e-12
Identities = 55/145 (37%), Positives = 77/145 (53%), Gaps = 11/145 (7%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289
++ K+N++R + +E++R+ L RS S + R+R S SR R R+RS S S+ R
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYKF-SRER-ASREESWESGRSER 344
+RSRSR R RR SRSRS SRG R S R RS K++ SRER R S ++ ++ R
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919
Query: 345 GPPDWRLESSNGKMASRRSEEKEAG 369
S SRR + G
Sbjct: 1920 ARSRTPSRRSRSHTPSRRRRSRSVG 1944
Score = 60.8 bits (146), Expect = 2e-09
Identities = 59/159 (37%), Positives = 73/159 (45%), Gaps = 16/159 (10%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277
R++ + R E++ KR+ R R+ R R SRRS S T RRRSRS RRR
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950
Query: 278 ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAKYKFSRER 330
RRSR+ SR R SR RSR RR R+ RSR+ SR R SR R ++ R
Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRR-- 2007
Query: 331 ASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAG 369
R S R R R S + +RS E G
Sbjct: 2008 --RSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG 2044
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRD 297
K ++ ++ + R++ E+ +R S RSR +R + S SR+R SRSR+R
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSL-------RSRSKRSKSSEHKSRKRTSESRSRARK 1849
Query: 298 R---HRRHRS--RSRSHSRGHRRASRDRS---AKYKFSRERASREESWESGRSER 344
R + HRS RSRS SR RR+SR RS + S+E+ R S ER
Sbjct: 1850 RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
RR + G + R R++ + R R R R R SRRS R
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993
Query: 264 TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
T RRR RSR RRRS S S R R L R SR RR RSRS R +R
Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284
R++ + +R++ RR R R SRRS + +R R R R RRRRSRS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 285 RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
R RR S S RSR RR SRS + R + R RS K
Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 70.9 bits (172), Expect = 2e-12
Identities = 51/136 (37%), Positives = 68/136 (50%), Gaps = 7/136 (5%)
Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR--RSRSRDRRRRRSRSTSRER 287
K+ + R++ R RRR R R + RRS S+ + +R + RS+ R R+R RS+SR+
Sbjct: 1855 KSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDN 1914
Query: 288 RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPP 347
RK R+RSR RR RS + S R R R RS + S R SR S S R
Sbjct: 1915 RKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRS--FSISPSRRSRTPSRRSRTPSRRS- 1971
Query: 348 DWRLESSNGKMASRRS 363
R S + SRRS
Sbjct: 1972 --RTPSRRSRTPSRRS 1985
Score = 70.1 bits (170), Expect = 3e-12
Identities = 55/145 (37%), Positives = 77/145 (53%), Gaps = 11/145 (7%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRS----GSRTRDRRR-SRSRDRRRRRSRSTSRERRK 289
++ K+N++R + +E++R+ L RS S + R+R S SR R R+RS S S+ R
Sbjct: 1801 EKSKKNKNRDKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRS-SKSKSHRS 1859
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRAS---RDRSAKYKF-SRER-ASREESWESGRSER 344
+RSRSR R RR SRSRS SRG R S R RS K++ SRER R S ++ ++ R
Sbjct: 1860 QTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVR 1919
Query: 345 GPPDWRLESSNGKMASRRSEEKEAG 369
S SRR + G
Sbjct: 1920 ARSRTPSRRSRSHTPSRRRRSRSVG 1944
Score = 60.8 bits (146), Expect = 2e-09
Identities = 59/159 (37%), Positives = 73/159 (45%), Gaps = 16/159 (10%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD-RRRSRSRDRRR--- 277
R++ + R E++ KR+ R R+ R R SRRS S T RRRSRS RRR
Sbjct: 1891 RKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFS 1950
Query: 278 ----RRSRSTSRERRKLSRSRSRDRHRRHRS---RSRSHSRGHRRASRDRSAKYKFSRER 330
RRSR+ SR R SR RSR RR R+ RSR+ SR R SR R ++ R
Sbjct: 1951 ISPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRR-- 2007
Query: 331 ASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAG 369
R S R R R S + +RS E G
Sbjct: 2008 --RSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERG 2044
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/115 (34%), Positives = 58/115 (50%), Gaps = 15/115 (13%)
Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRD 297
K ++ ++ + R++ E+ +R S RSR +R + S SR+R SRSR+R
Sbjct: 1797 KDTHEKSKKNKNRDKGEKEKKRDSSL-------RSRSKRSKSSEHKSRKRTSESRSRARK 1849
Query: 298 R---HRRHRS--RSRSHSRGHRRASRDRS---AKYKFSRERASREESWESGRSER 344
R + HRS RSRS SR RR+SR RS + S+E+ R S ER
Sbjct: 1850 RSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKRSPKHRSKSRER 1904
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 9/117 (7%)
Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
RR + G + R R++ + R R R R R SRRS R
Sbjct: 1937 RRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSR-RSRTPSRRSRTPSRRS--R 1993
Query: 264 TRDRRRSRSRDRRRRRSRSTS-----RERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
T RRR RSR RRRS S S R R L R SR RR RSRS R +R
Sbjct: 1994 TPSRRR-RSRSVVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/104 (37%), Positives = 49/104 (47%), Gaps = 10/104 (9%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERL-SRRSGSRTRDRRRSRSRDR---RRRRSRSTS 284
R++ + +R++ RR R R SRRS + +R R R R RRRRSRS
Sbjct: 1946 RRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVV 2005
Query: 285 RERRKLSRS-----RSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
R RR S S RSR RR SRS + R + R RS K
Sbjct: 2006 R-RRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPK 2048
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 70.1 bits (170), Expect = 3e-12
Identities = 49/144 (34%), Positives = 69/144 (47%), Gaps = 15/144 (10%)
Query: 234 EKQEKRNQDRLRRREERER----------EERLSRRSGSRTRDRRRSRSRDRRRRRSRST 283
+K+EKR R R R R R R RRS S++R RRRS+S RRR SR
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRER 300
Query: 284 SRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSE 343
R R S++R + + + + RS++ + + A R RSA SRER R S RS
Sbjct: 301 GRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSA----SRER-RRRRSRSGTRSP 355
Query: 344 RGPPDWRLESSNGKMASRRSEEKE 367
+ P + + S R +EK+
Sbjct: 356 KKPRSPKRKLSRSPSPRRHKKEKK 379
Score = 64.7 bits (156), Expect = 1e-10
Identities = 50/176 (28%), Positives = 75/176 (42%), Gaps = 30/176 (17%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRR------------- 268
R + R++ ++ + +R RRR RE RS S+TRD++
Sbjct: 268 RSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP 327
Query: 269 ---------RSRSRDRRRRRSRSTSRE-------RRKLSRSRSRDRHRRHRSRSRSHSRG 312
RS SR+RRRRRSRS +R +RKLSRS S RH++ + + + R
Sbjct: 328 KSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERS 387
Query: 313 HRRASRDRSAKYKFSRERASREESWESGRS-ERGPPDWRLESSNGKMASRRSEEKE 367
R S K K + RE ES + ++ D+ E + EEK+
Sbjct: 388 RDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKK 443
Score = 60.1 bits (144), Expect = 3e-09
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 8/138 (5%)
Query: 233 AEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR-RRRRSRSTSRERRKLS 291
++ K ++ ++R E + + + RR SRSR R RRRR+ S+SR RR S
Sbjct: 212 SDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRS 271
Query: 292 RSRSRDRHRRHRSRSRSHSRGHRRA-SRDRSAKYK-FSRERASREESWESGRSERGPPDW 349
RSR R H + RSR RS S RR+ SR+R + + S+ R ++E E RS+ P +
Sbjct: 272 RSRRRS-HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSY 330
Query: 350 ----RLESSNGKMASRRS 363
R S++ + RRS
Sbjct: 331 STARRSRSASRERRRRRS 348
Score = 36.6 bits (83), Expect = 0.037
Identities = 28/113 (24%), Positives = 41/113 (36%), Gaps = 5/113 (4%)
Query: 260 SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR-----GHR 314
S S D + +R + S + + ++ R RSRSRS R
Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266
Query: 315 RASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
R SR RS + S+ R+ R R R S K ++ E+KE
Sbjct: 267 RRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKE 319
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 70.1 bits (170), Expect = 3e-12
Identities = 49/140 (35%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGS----RTRDRRRSRSRDRRRRRSRSTSRERRK 289
E K+ +R R + R R S RS S R+R R RSRS + RSRS+SRER +
Sbjct: 191 EDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDW 349
S+SR R HR S R + +S K SR R+S + R+ P+
Sbjct: 251 SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPER 310
Query: 350 RLESSNGK--MASRRSEEKE 367
R SS+G SR S +K+
Sbjct: 311 RHRSSSGSSHSGSRSSSKKK 330
Score = 55.8 bits (133), Expect = 6e-08
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 8/173 (4%)
Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-L 256
G +D R + GK +G I ++++ E+ E + + + E+ + ++ L
Sbjct: 122 GEYDEFGRKKKKYRGKA-VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315
S+ + + + ++ + RR RS+S S R SRS S R R RSRSRS S
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ-- 238
Query: 316 ASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEA 368
SR RS+ + SR R S+ S S RS RG R S + +S K +
Sbjct: 239 -SRSRSSSRERSRSRGSKSRS--SSRSHRGSSSPRKRSYSSSSSSPERNRKRS 288
Score = 53.9 bits (128), Expect = 2e-07
Identities = 57/237 (24%), Positives = 92/237 (38%), Gaps = 51/237 (21%)
Query: 84 LDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQL 143
L ++ ES E D +L+K +L E ++E A++S L
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY-------------------NL 185
Query: 144 GAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND 203
A D ++K + +++ + R+S P+SS + + R S+
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS-------- 237
Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
Q R + ++ + + R+ R R R+ S S S
Sbjct: 238 ----------------QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
Query: 264 TRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
R+R+RS RSRS+S RK R+RSR RRHRS S S G R +S+ +
Sbjct: 282 ERNRKRS--------RSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKKK 330
Score = 52.0 bits (123), Expect = 9e-07
Identities = 39/114 (34%), Positives = 50/114 (43%), Gaps = 4/114 (3%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
R + R++ R R + R S R SR+R S+SR R S+S +R
Sbjct: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG---SKSRSSSRSHRGSSSPRKR 272
Query: 289 KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRS 342
S S S R RSRSRS S G R+ R RS + R R+S S RS
Sbjct: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPE-RRHRSSSGSSHSGSRS 325
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/294 (24%), Positives = 120/294 (40%), Gaps = 29/294 (9%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK---LLAKAEQLGAEGNV-DESQKI 155
R E ++ L + Q E + + + K E+NE I K L+ E A+G+V +E ++
Sbjct: 428 RKEKEQQLLHDKQMEEEKQQTERVTK--EMNEFIHKEQNSLSLLEAREADGDVVNEKKRT 485
Query: 156 LMEVEKVRAKKKEAEEEY-----RNSMPASSFQQQKLRVCEVCS-----AYLGLHDNDRR 205
E V KKE +E+ R+ +S R S +Y + R
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 206 LADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSG-SRT 264
+ K + R + R++ + +R + R + R+ R S R+ R
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 265 RDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
R R RS SR+RRR RSRS R + SRSRSRDR + R H+ + +
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 325 KFSRERA------------SREESWESGRSERGPPDWRLESSNGKMASRRSEEK 366
K R R+ RE+ + +R D++ S + ++ +R E+
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/319 (21%), Positives = 135/319 (42%), Gaps = 41/319 (12%)
Query: 72 EIASKERDLFF--ELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHEL 129
E +KE + F E +++ LE+ A+ D E KKR T E ++ + K E H+
Sbjct: 449 ERVTKEMNEFIHKEQNSLSLLEAREADGDVVNE--KKR---TPNETTSVLEPKKE--HKE 501
Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRV 189
E+ G+ + + G+ + + V + + R S +SS +++K
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSS--SSYSSSSGSSRTSSRSSSPKRKKRHS 559
Query: 190 CEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVA-EKQEKRNQDRLRRRE 248
R + + + ++IR++ R ++ E++ R+ R RRR
Sbjct: 560 RSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRS 619
Query: 249 E-REREERLSRRSGSRTRDRRR------------------SRSRDRRRRRSRSTSRERRK 289
R R+ R +R S SR+RDRR+ ++ ++R++ RSRS ++R+K
Sbjct: 620 RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK 679
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDW 349
+ R R++ +R + R ++ K+ +R R+ E S G
Sbjct: 680 KDKEREREQDKRKEKQKR----------EEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
Query: 350 RLESSNGKMASRRSEEKEA 368
++ + + S++S K++
Sbjct: 730 KIIRHDSRQDSKKSTTKDS 748
Score = 49.7 bits (117), Expect = 4e-06
Identities = 52/217 (23%), Positives = 98/217 (45%), Gaps = 28/217 (12%)
Query: 152 SQKILMEVEKVRAKKKEAEEEYRNSM---------PASSFQQQKLRVCEVCSAYLGL-HD 201
S++I +E + R K ++ RNS+ P+ ++ + R + +
Sbjct: 577 SRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRS 636
Query: 202 NDRRLADHFGGKL------HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREER-EREE 254
DRR D G L H G + +E+ + +++ + ++K++++R R +++R E+++
Sbjct: 637 RDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
Query: 255 RLSRRSGSRTRDRRRSRSRDRRRRRSRS----------TSRERRKLSRSRSRDRHRRHRS 304
R + ++D R R R+ R SRS SR+ K S ++ +H S
Sbjct: 697 REEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDS 756
Query: 305 RSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
RS S + ++ K K SR R S E+S SG+
Sbjct: 757 SGRSSSESPGSSKEKKAKKPKHSRSR-SVEKSQRSGK 792
Score = 38.1 bits (87), Expect = 0.013
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 20/128 (15%)
Query: 222 REKLDQLRKTVAEKQEK-----RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
RE+ RK +++EK DRL+R+ E ER RSGS + R D R
Sbjct: 684 REREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR---HDSR 737
Query: 277 RRRSRSTSRERRKLSRSRSRDR--------HRRHRSRSRSHSRGHRRASRDRSAKYKFSR 328
+ +ST+++ +K S S S R + +++ HSR RS K K SR
Sbjct: 738 QDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGK-KASR 796
Query: 329 ERASREES 336
+ S+ S
Sbjct: 797 KHKSKSRS 804
Score = 32.7 bits (73), Expect = 0.54
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 18/198 (9%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKIL- 156
DRRT A + + + +I + + H+ E + K E+ ++D+ +K
Sbjct: 625 DRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER---SRSIDKDRKKKD 681
Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
E E+ + K+KE ++ SS Q +L+ +++R + G + +
Sbjct: 682 KEREREQDKRKEKQKREEKDFKFSS-QDDRLK---------RKRESERTFSR--SGSISV 729
Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
I+ + D + T + ++ D R S+ ++ RSRS ++
Sbjct: 730 KIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS--SKEKKAKKPKHSRSRSVEKS 787
Query: 277 RRRSRSTSRERRKLSRSR 294
+R + SR+ + SRSR
Sbjct: 788 QRSGKKASRKHKSKSRSR 805
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/294 (24%), Positives = 120/294 (40%), Gaps = 29/294 (9%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK---LLAKAEQLGAEGNV-DESQKI 155
R E ++ L + Q E + + + K E+NE I K L+ E A+G+V +E ++
Sbjct: 428 RKEKEQQLLHDKQMEEEKQQTERVTK--EMNEFIHKEQNSLSLLEAREADGDVVNEKKRT 485
Query: 156 LMEVEKVRAKKKEAEEEY-----RNSMPASSFQQQKLRVCEVCS-----AYLGLHDNDRR 205
E V KKE +E+ R+ +S R S +Y + R
Sbjct: 486 PNETTSVLEPKKEHKEKEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRT 545
Query: 206 LADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSG-SRT 264
+ K + R + R++ + +R + R + R+ R S R+ R
Sbjct: 546 SSRSSSPKRKKRHSRSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERE 605
Query: 265 RDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
R R RS SR+RRR RSRS R + SRSRSRDR + R H+ + +
Sbjct: 606 RRRNRSPSRERRRSRSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQER 665
Query: 325 KFSRERA------------SREESWESGRSERGPPDWRLESSNGKMASRRSEEK 366
K R R+ RE+ + +R D++ S + ++ +R E+
Sbjct: 666 KKERSRSIDKDRKKKDKEREREQDKRKEKQKREEKDFKFSSQDDRLKRKRESER 719
Score = 58.2 bits (139), Expect = 1e-08
Identities = 68/319 (21%), Positives = 135/319 (42%), Gaps = 41/319 (12%)
Query: 72 EIASKERDLFF--ELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHEL 129
E +KE + F E +++ LE+ A+ D E KKR T E ++ + K E H+
Sbjct: 449 ERVTKEMNEFIHKEQNSLSLLEAREADGDVVNE--KKR---TPNETTSVLEPKKE--HKE 501
Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRV 189
E+ G+ + + G+ + + V + + R S +SS +++K
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSS--SSYSSSSGSSRTSSRSSSPKRKKRHS 559
Query: 190 CEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVA-EKQEKRNQDRLRRRE 248
R + + + ++IR++ R ++ E++ R+ R RRR
Sbjct: 560 RSRSPTIKARRSRSRSYSRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRS 619
Query: 249 E-REREERLSRRSGSRTRDRRR------------------SRSRDRRRRRSRSTSRERRK 289
R R+ R +R S SR+RDRR+ ++ ++R++ RSRS ++R+K
Sbjct: 620 RSRSRDRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKK 679
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDW 349
+ R R++ +R + R ++ K+ +R R+ E S G
Sbjct: 680 KDKEREREQDKRKEKQKR----------EEKDFKFSSQDDRLKRKRESERTFSRSGSISV 729
Query: 350 RLESSNGKMASRRSEEKEA 368
++ + + S++S K++
Sbjct: 730 KIIRHDSRQDSKKSTTKDS 748
Score = 49.7 bits (117), Expect = 4e-06
Identities = 52/217 (23%), Positives = 98/217 (45%), Gaps = 28/217 (12%)
Query: 152 SQKILMEVEKVRAKKKEAEEEYRNSM---------PASSFQQQKLRVCEVCSAYLGL-HD 201
S++I +E + R K ++ RNS+ P+ ++ + R + +
Sbjct: 577 SRRIKIESNRARVKIRDRRRSNRNSIERERRRNRSPSRERRRSRSRSRDRRTNRASRSRS 636
Query: 202 NDRRLADHFGGKL------HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREER-EREE 254
DRR D G L H G + +E+ + +++ + ++K++++R R +++R E+++
Sbjct: 637 RDRRKIDDQRGNLSGNSHKHKGEAKEQERKKERSRSIDKDRKKKDKEREREQDKRKEKQK 696
Query: 255 RLSRRSGSRTRDRRRSRSRDRRRRRSRS----------TSRERRKLSRSRSRDRHRRHRS 304
R + ++D R R R+ R SRS SR+ K S ++ +H S
Sbjct: 697 REEKDFKFSSQDDRLKRKRESERTFSRSGSISVKIIRHDSRQDSKKSTTKDSKKHSGSDS 756
Query: 305 RSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
RS S + ++ K K SR R S E+S SG+
Sbjct: 757 SGRSSSESPGSSKEKKAKKPKHSRSR-SVEKSQRSGK 792
Score = 38.1 bits (87), Expect = 0.013
Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 20/128 (15%)
Query: 222 REKLDQLRKTVAEKQEK-----RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
RE+ RK +++EK DRL+R+ E ER RSGS + R D R
Sbjct: 684 REREQDKRKEKQKREEKDFKFSSQDDRLKRKRE---SERTFSRSGSISVKIIR---HDSR 737
Query: 277 RRRSRSTSRERRKLSRSRSRDR--------HRRHRSRSRSHSRGHRRASRDRSAKYKFSR 328
+ +ST+++ +K S S S R + +++ HSR RS K K SR
Sbjct: 738 QDSKKSTTKDSKKHSGSDSSGRSSSESPGSSKEKKAKKPKHSRSRSVEKSQRSGK-KASR 796
Query: 329 ERASREES 336
+ S+ S
Sbjct: 797 KHKSKSRS 804
Score = 32.7 bits (73), Expect = 0.54
Identities = 40/198 (20%), Positives = 81/198 (40%), Gaps = 18/198 (9%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKIL- 156
DRRT A + + + +I + + H+ E + K E+ ++D+ +K
Sbjct: 625 DRRTNRASRSRSRDRRKIDDQRGNLSGNSHKHKGEAKEQERKKER---SRSIDKDRKKKD 681
Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
E E+ + K+KE ++ SS Q +L+ +++R + G + +
Sbjct: 682 KEREREQDKRKEKQKREEKDFKFSS-QDDRLK---------RKRESERTFSR--SGSISV 729
Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR 276
I+ + D + T + ++ D R S+ ++ RSRS ++
Sbjct: 730 KIIRHDSRQDSKKSTTKDSKKHSGSDSSGRSSSESPGS--SKEKKAKKPKHSRSRSVEKS 787
Query: 277 RRRSRSTSRERRKLSRSR 294
+R + SR+ + SRSR
Sbjct: 788 QRSGKKASRKHKSKSRSR 805
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 69.3 bits (168), Expect = 5e-12
Identities = 55/148 (37%), Positives = 73/148 (49%), Gaps = 15/148 (10%)
Query: 229 RKTVAEKQEKRNQDRLRRRE-ERERE---ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTS 284
R+ E+Q++R++ R R RE ERE E ER +R R DR R + RDR R+R +
Sbjct: 52 REKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRN 111
Query: 285 RER-RKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYKFSRER---ASREESWES 339
RER RK R R + R R R R R R R R R K + RER A REE +
Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQR-ERERQRQRERKRETDRERQRWAEREERKKE 170
Query: 340 GRSERGPPDWRLESSNGKMASRRSEEKE 367
+ ER + E K +R E+K+
Sbjct: 171 RKKER-----KKERKEKKKEEKRREDKK 193
Score = 65.9 bits (159), Expect = 6e-11
Identities = 39/116 (33%), Positives = 55/116 (47%), Gaps = 4/116 (3%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER- 287
RK +++ +++DR R+RE ER R G R RD++ R RDR R R R RER
Sbjct: 88 RKRQTDRERDKDRDRERKRETDRNRER--NRKGGRERDKQTERERDRERERQRQRERERQ 145
Query: 288 RKLSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRS 342
R+ R R DR R R R + ++R K K + R ++ W G S
Sbjct: 146 RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEGIS 201
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/176 (30%), Positives = 77/176 (43%), Gaps = 34/176 (19%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREER-EREERLSRRSGSRTRDRRRSR--------SRDRR 276
++ R+T K+ +R +DR R RE + ERE R +R R RDR+ R RDR+
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQ 65
Query: 277 RRRSRSTSRE-------------RRKLSRSRSRDRHRRH-----RSRSRSHSRGHRR--- 315
R+R R T RE +R+ R R +DR R R+R R+ G R
Sbjct: 66 RQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQ 125
Query: 316 --ASRDRSAKYKFSRERASREESWESGRSERGPPDW--RLESSNGKMASRRSEEKE 367
RDR + + RER + + ++R W R E + R+ E KE
Sbjct: 126 TERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKE 181
Score = 59.3 bits (142), Expect = 5e-09
Identities = 42/138 (30%), Positives = 60/138 (43%), Gaps = 8/138 (5%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
+++ KR DR +E ERE R ++T R R RDR R R R T RE+ + R
Sbjct: 4 QRERKRETDR---GKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKER-ERQ 59
Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRER---ASREESWESGRS-ERGPPDW 349
+ RDR R+ + + R R R K + RER RE E+ R+ ER
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 350 RLESSNGKMASRRSEEKE 367
R + R E++
Sbjct: 120 RERDKQTERERDRERERQ 137
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/121 (31%), Positives = 59/121 (48%), Gaps = 6/121 (4%)
Query: 234 EKQEKRNQDRLRRRE-ERERE---ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
E+Q +R + R R+R+ +RER+ +R +R R R+R R R+R ++ R RER +
Sbjct: 77 ERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERER 136
Query: 290 LSRSRSRDRHR-RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPD 348
R R R+R R R R R R +R + K R++ +E+ E R E
Sbjct: 137 -QRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
Query: 349 W 349
W
Sbjct: 196 W 196
Score = 52.8 bits (125), Expect = 5e-07
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR----RRRSR 281
D+ RK ++ +RN+ R R+++ ER R R R+R R R R+R+ R R R
Sbjct: 101 DRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
RE RK R + R + R+ + + +R
Sbjct: 161 WAEREERKKERKKERKKERKEKKKEEKRREDKKR 194
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 4/91 (4%)
Query: 254 ERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGH 313
ER R R + R RDR+R R T RE +R R RDRHR ++
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERE----NRHRQRDRHRERDRQTDREKERE 57
Query: 314 RRASRDRSAKYKFSRERASREESWESGRSER 344
R+ RDR + + ER + + + ER
Sbjct: 58 RQKERDRQRQRERETERETERQRERQRQRER 88
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 68.9 bits (167), Expect = 7e-12
Identities = 38/146 (26%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
+EK + ++ +++E++ ++R ++R+ER +ER R+ + R+R++ R+R++++ R
Sbjct: 61 KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
RER R + + RR + R + R R R+R K R++ RE+ E R
Sbjct: 121 K-ERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRK---KRKKEEREKKRERNR 176
Query: 342 SERGPPDWRLESSNGKMASRRSEEKE 367
ER R E K ++ K+
Sbjct: 177 KERKKERERKERRERKKERKKERRKK 202
Score = 67.0 bits (162), Expect = 3e-11
Identities = 31/133 (23%), Positives = 63/133 (47%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSR 294
+ E++ + R R + +RERE+ R G + + +R+ R R + R R R ++RK R +
Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92
Query: 295 SRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESS 354
R + ++ + + RG R + + K + + RE + R ++ + + E
Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 355 NGKMASRRSEEKE 367
GK +R + K+
Sbjct: 153 RGKRERKRKKRKK 165
Score = 66.2 bits (160), Expect = 4e-11
Identities = 39/150 (26%), Positives = 70/150 (46%), Gaps = 7/150 (4%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
RE+ + R+ E++ +R + ++R++RER + R+ R + R+ R ++RR+R+
Sbjct: 41 REREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKE 100
Query: 282 STSRERRKLS-RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESG 340
RER++ R R + + R+ R R R +R R + + R R+ E G
Sbjct: 101 KKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK------KKRRKERKREKERG 154
Query: 341 RSERGPPDWRLESSNGKMASRRSEEKEAGE 370
+ ER + E K R E K+ E
Sbjct: 155 KRERKRKKRKKEEREKKRERNRKERKKERE 184
Score = 65.9 bits (159), Expect = 6e-11
Identities = 34/126 (26%), Positives = 69/126 (54%), Gaps = 2/126 (1%)
Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-RSGSRTRDRRRSRSRDRRRR 278
Q +E+ ++ R+ ++++KR + + RRE ++++ER R R + R+R+R + R ++RR
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 279 RSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWE 338
+ R +ER K R R + R + R + R +R R+ R+R + + +ER +
Sbjct: 145 KERKREKERGKRERKRKK-RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 339 SGRSER 344
+ +R
Sbjct: 204 ERKKDR 209
Score = 64.3 bits (155), Expect = 2e-10
Identities = 35/146 (23%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
RE+ + +K +++ + ++R R+ E++R+ER + R +++++ R R +R RR R
Sbjct: 56 RERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK-RERKQRGRRER 114
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
+ER++ R + R R+ + R + R R+ ++R K R+R R++ +
Sbjct: 115 KKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG---KRERKRKKRKKEEREKK 171
Query: 342 SERGPPDWRLESSNGKMASRRSEEKE 367
ER + + E + R+ E K+
Sbjct: 172 RERNRKERKKERERKERRERKKERKK 197
Score = 63.2 bits (152), Expect = 4e-10
Identities = 31/145 (21%), Positives = 68/145 (46%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSR 281
R+K ++ ++ +++E+ Q + RR +ER + ++ ++ + R RR + + R+ R R
Sbjct: 66 RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER 125
Query: 282 STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGR 341
+ R + + R + + R+ R R + + R+ + + + + RER +E E R
Sbjct: 126 ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERER 185
Query: 342 SERGPPDWRLESSNGKMASRRSEEK 366
ER + K R+ + K
Sbjct: 186 KERRERKKERKKERRKKKERKKDRK 210
Score = 62.8 bits (151), Expect = 5e-10
Identities = 36/127 (28%), Positives = 69/127 (54%), Gaps = 7/127 (5%)
Query: 222 REKLDQLRKTVAEKQEKRNQDRLRRREEREREER----LSRRSGSRTRDRRRSRSRDRRR 277
REK + RK +K+E++ + R R++++ER+ER RR R + R++ R ++R+R
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
+ R RER++ R + +R R+R R+ R+R + K +ER ++E
Sbjct: 150 EKERG-KRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERK--KERRKKKERK 206
Query: 338 ESGRSER 344
+ +++R
Sbjct: 207 KDRKTDR 213
Score = 59.3 bits (142), Expect = 5e-09
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 6/126 (4%)
Query: 245 RRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRS 304
R++E RERE+R R R R+R + + + +R++R R RER++ R + R R
Sbjct: 36 RKKERREREKRKREREKERKRERGK-KEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 305 RSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSE 364
R R + R + + K +ER RE + R + R + K R
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERK-----RKKRRKKKRRKERKR 149
Query: 365 EKEAGE 370
EKE G+
Sbjct: 150 EKERGK 155
Score = 58.5 bits (140), Expect = 9e-09
Identities = 48/231 (20%), Positives = 97/231 (41%), Gaps = 32/231 (13%)
Query: 94 IAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
+ C ++ +R +E ++E K E+ E E GK K + G E +
Sbjct: 19 MVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK 78
Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
+ E EK R +++E E R ++Q+ G + ++
Sbjct: 79 R--KEREKQRKERREKERRKRKKEKKKRERKQR-----------GRRERKKK-------- 117
Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR-RREEREREERLSRRSGSRTRDRRRSRS 272
+E+ ++ R+ ++ KR + R + RR+ER+RE+ +R R R +R+
Sbjct: 118 --------KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRE--RKRKKRKKEE 167
Query: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323
R+++R R+R ++ R+ R R + R+ R + + R+ R ++
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 57.0 bits (136), Expect = 3e-08
Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 6/122 (4%)
Query: 246 RREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSR 305
+RE ++ER R R R++ R R R ++ + ++R+K R + R+R R+ R +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEK------KKRKKRERGKERERKRKEREK 84
Query: 306 SRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEE 365
R R R R + K + ++R RE + R ER + + K ++
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 366 KE 367
KE
Sbjct: 145 KE 146
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/202 (23%), Positives = 81/202 (40%), Gaps = 7/202 (3%)
Query: 96 ECDRRTELAK--KRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQ 153
E +R+ E + KR E ++E E K EK E GK + E+ E +
Sbjct: 33 ESERKKERREREKRKREREKERKRE-RGKKEKKKRKKRERGK---ERERKRKEREKQRKE 88
Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
+ E K + +KK+ E + R +++K R E R+ K
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 214 LHLGFIQIREKLDQLRKTVAEKQEKRNQ-DRLRRREEREREERLSRRSGSRTRDRRRSRS 272
+ K + +K EK+ +RN+ +R + RE +ER ER R R + + R +
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 273 RDRRRRRSRSTSRERRKLSRSR 294
R R+ R R+ + +R
Sbjct: 209 RKTDRQTDSQVFRPLRESAFNR 230
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 68.9 bits (167), Expect = 7e-12
Identities = 58/165 (35%), Positives = 75/165 (45%), Gaps = 14/165 (8%)
Query: 207 ADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRD 266
AD + + G I+ R D R + N +R E++ R SGSR+R
Sbjct: 139 ADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDKPRTSHRRSYSGSRSRS 198
Query: 267 RRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKF 326
R R RSR R RR SRS S R +S+SRSR R RS+ RS SR R SR +S K K
Sbjct: 199 RSRRRSRSRSRRSSRSRS---RSISKSRSRS---RSRSKGRSRSRSKGRKSRSKS-KSKP 251
Query: 327 SRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGEI 371
+R S S + E E S + SR +E G+I
Sbjct: 252 KSDRGSHSHSRSRSKDE-------YEKSRSRSRSRSPKENGKGDI 289
Score = 57.0 bits (136), Expect = 3e-08
Identities = 56/223 (25%), Positives = 91/223 (40%), Gaps = 15/223 (6%)
Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
++++E R ++ ++ R + + K R E + D R L G +
Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170
Query: 214 LH---LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRS 270
++ + I+ + + R + R++ R R R R R S SR+R R RS
Sbjct: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRS 230
Query: 271 RSRDRRR---RRSRSTSRERRKL-------SRSRSRDRHRRHRSRSRSHS--RGHRRASR 318
+ R R R R+SRS S+ + K SRSRS+D + + RSRSRS S + +
Sbjct: 231 KGRSRSRSKGRKSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIK 290
Query: 319 DRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASR 361
+S SR + RS PP S + S+
Sbjct: 291 SKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSK 333
Score = 35.8 bits (81), Expect = 0.063
Identities = 33/110 (30%), Positives = 46/110 (41%), Gaps = 9/110 (8%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
RK+ ++ + K DR R SR + R RSRSR + + R
Sbjct: 241 RKSRSKSKSKPKSDRGSHSHSR------SRSKDEYEKSRSRSRSRSPKENGKGDIKSKSR 294
Query: 289 KLSRSRSRDRHRRHRSRSRSHSRGHRRA---SRDRSAKYKFSRERASREE 335
S+SRS S++RS S +RA SR RS SR R+S +
Sbjct: 295 SRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRSKSRSRSRSSSRD 344
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 68.6 bits (166), Expect = 9e-12
Identities = 54/160 (33%), Positives = 75/160 (46%), Gaps = 22/160 (13%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSR 285
D++RKT + RNQ+ + R++ RS SR+R + ++SR R R S S SR
Sbjct: 1279 DEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSR 1338
Query: 286 ER----------RKLSRSRSRDRHRRHRSRSRSHS----RGHRRASRDRSAKYKFSRERA 331
R R SRSRSR + R R+RSRS S + HR +SR RS +
Sbjct: 1339 SRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSR 1398
Query: 332 SREESWES--------GRSERGPPDWRLESSNGKMASRRS 363
SR +++S RS+R R S N + S RS
Sbjct: 1399 SRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRS 1438
Score = 45.4 bits (106), Expect = 8e-05
Identities = 49/155 (31%), Positives = 71/155 (45%), Gaps = 9/155 (5%)
Query: 215 HLGFIQIREKLDQLRKTVAE----KQEKRNQ-DRLRRREEREREERLSRRSGSRT-RDRR 268
HL IQ L +++T + K+EK ++ D+ + +R S RS SR+ R R
Sbjct: 642 HLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRS 701
Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSR 328
SRS R R + S SR R SRS SR+++ H SRS S + R AK R
Sbjct: 702 YSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAK---RR 758
Query: 329 ERASREESWESGRSERGPPDWRLESSNGKMASRRS 363
R+S +++ S + + L S K R S
Sbjct: 759 LRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSS 793
Score = 45.1 bits (105), Expect = 1e-04
Identities = 62/226 (27%), Positives = 96/226 (42%), Gaps = 32/226 (14%)
Query: 158 EVEKVRAKKKEAEEEYRN----SMPASS-FQQQKLRVCEVCSAYLGLHDNDRRLADHFGG 212
E++++RA + + E++ S P SS + ++ L +Y G + +D A H G
Sbjct: 368 EMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYY-SDLSTARHSG- 425
Query: 213 KLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS----RRSGSRTRDRR 268
K + K V K++ + Q RR ++ ++ L S S TR +
Sbjct: 426 ---------HHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMK 476
Query: 269 RSRSRDRRRRRSRSTSRERRKLSRSRSRD-------RHRRHRSRSRSHSRGHRR-ASRDR 320
S R+R R S +S K S+S R RS+SHS+ + R +SR R
Sbjct: 477 SSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSR 536
Query: 321 SAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEK 366
+A S R SR +S S +S R S K AS+ SE K
Sbjct: 537 TASKSSSHSR-SRSKSRSSSKSGHRK---RASKSPRKTASQLSENK 578
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/120 (32%), Positives = 50/120 (41%), Gaps = 10/120 (8%)
Query: 239 RNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRR---------RRRSRSTSRERRK 289
R++ R R R SR G +R R RSRS R R RSRS+S +
Sbjct: 1338 RSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHS 1397
Query: 290 LSRSRSRDRH-RRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPD 348
SRS + D + R RSRSRS R + + + R S ES S R P +
Sbjct: 1398 RSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/126 (34%), Positives = 57/126 (45%), Gaps = 23/126 (18%)
Query: 259 RSGSRTRDRRRSRSRDRRRRRSRSTSRER----------RKLSRSRSRDRHR-RHRSR-- 305
R GS + R++ +RR R S+S E+ R SRSRS+ + RHR+R
Sbjct: 1273 RPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSV 1332
Query: 306 SRSHSRGHRRASRD--RSAKYKFSRERA--------SREESWESGRSERGPPDWRLESSN 355
S SHSR R+S RS Y SR R SR S+ S +S R R SS+
Sbjct: 1333 SYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSS 1392
Query: 356 GKMASR 361
SR
Sbjct: 1393 YDPHSR 1398
Score = 36.6 bits (83), Expect = 0.037
Identities = 33/99 (33%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Query: 240 NQDRLRRREEREREERLSRRSGSRTRDRR-----RSRSRDRRRRRSRSTSRERRKLSRSR 294
++ R R R R + S R+ SR+R R SRSR S SR R + RS
Sbjct: 1363 SRGRTRSRSSSYRSYK-SHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSD 1421
Query: 295 SRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASR 333
S R R + RSRS + DRS + S +SR
Sbjct: 1422 SYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSR 1460
Score = 33.9 bits (76), Expect = 0.24
Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 1/121 (0%)
Query: 248 EEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSR 307
++R +E+++ + + + R + ++RR + E K S R + R RS
Sbjct: 428 KKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRS 487
Query: 308 SHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
S H + RD S K + + S +S RS+ + SS + AS+ S
Sbjct: 488 SSLSSHHSSKRDWSKSDK-DVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSR 546
Query: 368 A 368
+
Sbjct: 547 S 547
Score = 32.7 bits (73), Expect = 0.54
Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)
Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
K V EK+ K+ + S S + RSR R +RR S++RRK
Sbjct: 182 KDVFEKKRKK-PTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRK 240
Query: 290 LSRSRSRDRHRRHRSRSRSHSR---GHRRASRDRSAK 323
S S + +H + HS + + S D SAK
Sbjct: 241 -EASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAK 276
Score = 28.9 bits (63), Expect = 7.8
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRR- 278
Q +EK Q+ +T KQEK N+ + + ERE R D R+ S+ +R+
Sbjct: 823 QEKEKQGQMERT-HNKQEK-NRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNY 880
Query: 279 ---RSRSTSRERRKLSRSRSRDRH 299
+ S S R ++++ D H
Sbjct: 881 AGSKWDSESNSERDVTKNSKNDSH 904
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 66.6 bits (161), Expect = 3e-11
Identities = 46/143 (32%), Positives = 64/143 (44%), Gaps = 10/143 (6%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
E++ R DR R R+ + R R+RDRRR SR R R RS+S RERR R
Sbjct: 19 ERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERE 78
Query: 294 RSRDRHRRHRSRSRSHSRGHRR--------ASRDRSAKYKFSRERASREESWESGRSERG 345
R ++R R + R R GHRR S R +K ++R S+++ E ++
Sbjct: 79 RDKERDRNKKDRDRDKD-GHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDE-EDEHGDKK 136
Query: 346 PPDWRLESSNGKMASRRSEEKEA 368
P L + EE EA
Sbjct: 137 PKAQPLSLEELLAKKKAEEEAEA 159
Score = 34.3 bits (77), Expect = 0.18
Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 11/93 (11%)
Query: 222 REKLDQLRKTVAEKQEKRNQ---------DRLRRREEREREERLSRRSGSRTRDRRRSRS 272
++++++ ++ + E+++KR Q + + RE RER ER+ R + + R +
Sbjct: 178 QQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKI 237
Query: 273 RDRRRRRSRSTSRERRKLS--RSRSRDRHRRHR 303
R+ + + + + R L + R R RH R
Sbjct: 238 REEKDKSKELHAIKERYLGGIKKRRRTRHLNDR 270
Score = 32.0 bits (71), Expect = 0.92
Identities = 20/102 (19%), Positives = 39/102 (38%), Gaps = 6/102 (5%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRS 293
+K E+ + + + + ERE +R +R+R +R++R ++ + L R
Sbjct: 151 KKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKKR------KQFQDLGRK 204
Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
D R R R + D + K E+ +E
Sbjct: 205 MLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDKSKE 246
Score = 30.4 bits (67), Expect = 2.7
Identities = 19/98 (19%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 223 EKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRS 282
E L + ++ V E+Q ++R +R++ ++ L R+ ++R R R+R R +
Sbjct: 172 EALKRRQQEVEERQRMLEEERKKRKQFQD----LGRKMLEDPQERERRERRERMERETNG 227
Query: 283 TSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
E + +D+ + + + G ++ R R
Sbjct: 228 NEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTR 265
Score = 29.6 bits (65), Expect = 4.5
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 233 AEKQEKRNQDRLRRREERER--EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKL 290
AE++ + + R + EER+R EE +R + R+ R RR R RER +
Sbjct: 167 AEREAEALKRRQQEVEERQRMLEEERKKRKQFQDLGRKMLEDPQERERRER---RERMER 223
Query: 291 SRSRSRDRHRRHRSRSRSHSRGHRRASRDR 320
+ + D R + R A ++R
Sbjct: 224 ETNGNEDEEGRQKIREEKDKSKELHAIKER 253
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 65.5 bits (158), Expect = 7e-11
Identities = 60/223 (26%), Positives = 105/223 (47%), Gaps = 15/223 (6%)
Query: 154 KILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGK 213
++++E R ++ ++ R + + K R E ++ D R L G +
Sbjct: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
Query: 214 LHLGFIQ-IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERL--SRRSGSRTRDRRRS 270
++ I+ + +K R+ + ++ R R R R+ R S+ S S++R R RS
Sbjct: 165 VNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRS 224
Query: 271 RSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRA-SRDRSAKYKFSRE 329
SR R + RSRS SR R K +SRS + + SRSRSHS G R+ S+D++ + + +
Sbjct: 225 GSRSRSKSRSRSQSRSRSKKEKSRSPSKEK---SRSRSHSAGKSRSKSKDQAEEKIQNND 281
Query: 330 RASREESWESGRSERGPPDWRLES-SNGKMASRRSEEKEAGEI 371
+ +S R P + +S S + RR EE++ G +
Sbjct: 282 NVGKPKS-------RSPSRHKSKSKSRSRSQERRVEEEKRGSV 317
Score = 65.5 bits (158), Expect = 7e-11
Identities = 43/154 (27%), Positives = 72/154 (46%), Gaps = 2/154 (1%)
Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSRDRR 276
IQ + + + + + + +++ R R +E R EE+ S R++++ R+SRSR R
Sbjct: 277 IQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRS 336
Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREES 336
+ SRS SR R K R + R SRSRS SR SR R +K + +++
Sbjct: 337 KGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKK 396
Query: 337 WESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
++ RS+ P + S S+ + GE
Sbjct: 397 EDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/134 (32%), Positives = 66/134 (49%), Gaps = 10/134 (7%)
Query: 227 QLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
Q R+ EK+ ++ R + + R+ R + GSR+R R RS+S+D+R+ R RS
Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS---- 360
Query: 287 RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERA-----SREESWESGR 341
R+ SRSRSR R + RSR R R + S + K R ++ S + E +
Sbjct: 361 -REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAK 419
Query: 342 SERGPPDWRLESSN 355
SE + R ES N
Sbjct: 420 SESSQREGRGESEN 433
Score = 56.2 bits (134), Expect = 5e-08
Identities = 49/161 (30%), Positives = 78/161 (48%), Gaps = 19/161 (11%)
Query: 222 REKLDQLRKTVAEKQEKRNQD--RLRRREEREREERLSRRSG-----SRTRDRRRSRSRD 274
R K ++ R EK R+ + R + + + EE++ SR+ R +S+S+
Sbjct: 241 RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS 300
Query: 275 RRRRRSRSTSRERR-KLSRSRSRDRHRRHRSRSRSHSRGHRRA-------SRDRSAKYKF 326
R R + R E+R +SR RS+++ R +SRSRS S+G R+ S+D+ K
Sbjct: 301 RSRSQERRVEEEKRGSVSRGRSQEKSLR-QSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR 359
Query: 327 SRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
SRE SR S +SER R + K S + ++KE
Sbjct: 360 SREE-SRSRSRSRSKSERSRK--RGSKRDSKAGSSKKKKKE 397
Score = 52.8 bits (125), Expect = 5e-07
Identities = 61/268 (22%), Positives = 111/268 (41%), Gaps = 30/268 (11%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELN-EEIGKLLAKAEQLGAEGNVDESQKILME 158
R+ K++ +E S S A K + ++ + + + +G + S+
Sbjct: 239 RSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS 298
Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218
+ R++++ EEE R S+ Q++ LR R + GG
Sbjct: 299 KSRSRSQERRVEEEKRGSVSRGRSQEKSLR-------------QSRSRSRSKGGSRSRSR 345
Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR--RSGSRTRDRRRSRSRDRR 276
+ + K D+ + ++E R++ R R + ER R+ R ++GS + ++ R +
Sbjct: 346 SRSKSK-DKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 277 RRRSRSTSRERRKLSRSRSRDRHRRH-----------RSRSRSHSRGHRRASRDRSAKYK 325
R SRS S+ER ++S S R R RSRSRS+S+ + ++ K
Sbjct: 405 RSPSRSVSKEREH-AKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSK 463
Query: 326 FSRERASREESWESGRSERGPPDWRLES 353
+ + SR +S S + R P R S
Sbjct: 464 SASKTRSRSKS-RSRSASRSPSRSRSRS 490
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 65.5 bits (158), Expect = 7e-11
Identities = 52/143 (36%), Positives = 75/143 (52%), Gaps = 13/143 (9%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSR--SRDRRRRRSRSTSRE 286
R+ + + +D R R + +R RS ++ RDR +SR S +R R+SRS S+E
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKE 566
Query: 287 R-RKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERG 345
R R+ RS S++R RR +SRS S R H R SR + + +SR RAS +E S RS
Sbjct: 567 RDRRRWRSPSKERERR-QSRSSSEERDHSR-SRSPNKQSGYSRPRASSKEKAHS-RS--- 620
Query: 346 PPDWRLESSNGKMASRRSEEKEA 368
R S G + R+ KE+
Sbjct: 621 ----RTPSKEGNHSQSRTSSKES 639
Score = 65.5 bits (158), Expect = 7e-11
Identities = 50/142 (35%), Positives = 73/142 (51%), Gaps = 6/142 (4%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS--RDRRRRRSRSTSRE 286
R+ + + +DR + R E E RS S+ RDRRR RS ++R RR+SRS+S E
Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEE 590
Query: 287 RRKLSRSRSRDRHRRH-RSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERG 345
R SRSRS ++ + R R+ S + H R SR S + S+ R S +ES S +
Sbjct: 591 RDH-SRSRSPNKQSGYSRPRASSKEKAHSR-SRTPSKEGNHSQSRTSSKESDPSQSTVPR 648
Query: 346 PPDW-RLESSNGKMASRRSEEK 366
PDW R + ++ R+ K
Sbjct: 649 SPDWKRSPTRTSSLSQNRTPSK 670
Score = 64.7 bits (156), Expect = 1e-10
Identities = 52/146 (35%), Positives = 69/146 (47%), Gaps = 21/146 (14%)
Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRS--------------RDRRRRRSRSTSRE 286
+DR R R + + RS ++ RDR RSRS ++R RRSRS S+E
Sbjct: 447 RDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE 506
Query: 287 RR-KLSRSRSRDR-HRRHRSRSRSHSRGHRRA---SRDRSAKYKFSRERASREESWESGR 341
R+ + SRS S++R HRR RS S+ R R+ RDRS S ER R+ S
Sbjct: 507 RQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQS--RSPS 564
Query: 342 SERGPPDWRLESSNGKMASRRSEEKE 367
ER WR S + RS +E
Sbjct: 565 KERDRRRWRSPSKERERRQSRSSSEE 590
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/149 (34%), Positives = 73/149 (48%), Gaps = 23/149 (15%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRS--RDRRRRRSRSTSRER-RKLS 291
+ + +DR R R + + S S+ RD RRSRS ++R+ R+SRS+S+ER + S
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
Query: 292 RSRSRDRHRRH---------RSRSRSHS--RGHRRASRDRSAKYKFSRERASREESWESG 340
RS S++R RR RS+SRS S R HR++ S+ER R W S
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSP-------SKERDRRR--WRSP 575
Query: 341 RSERGPPDWRLESSNGKMASRRSEEKEAG 369
ER R S + RS K++G
Sbjct: 576 SKERERRQSRSSSEERDHSRSRSPNKQSG 604
Score = 54.7 bits (130), Expect = 1e-07
Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 10/138 (7%)
Query: 241 QDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSRDRH 299
+DR R R + + RS + RDR RSRS ++ R SRS S + R SRSRS +
Sbjct: 423 RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKE 482
Query: 300 RRHRSR-SRSHSRGHRRA---SRDRSAKYKFSR-----ERASREESWESGRSERGPPDWR 350
R H S S R HRR+ S++R + S R SR S E R + P+
Sbjct: 483 RDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 351 LESSNGKMASRRSEEKEA 368
+ S + S E +++
Sbjct: 543 RDRSQSRSPSEEREHRQS 560
Score = 53.5 bits (127), Expect = 3e-07
Identities = 49/136 (36%), Positives = 63/136 (46%), Gaps = 14/136 (10%)
Query: 235 KQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRS 293
+ + +DR R R + +R RS ++ RD RSRS + R RSRS S + R SRS
Sbjct: 405 RSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 294 RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRER-------ASREESWESGRSERGP 346
RS ++ R RSRSRS S+ RD S S+ER S+E RS
Sbjct: 465 RSPNK-ARDRSRSRSPSK-----ERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
Query: 347 PDWRLESSNGKMASRR 362
D R S K RR
Sbjct: 519 RDHRRSRSPSKERQRR 534
Score = 53.1 bits (126), Expect = 4e-07
Identities = 44/133 (33%), Positives = 65/133 (48%), Gaps = 6/133 (4%)
Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-RKLSRSRSR 296
++ R + ++ + RS ++ RDR RSRS + R RSRS S + R SRSRS
Sbjct: 384 RKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSP 443
Query: 297 DRHR-RHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSN 355
+ R R RSRS + +R H SR RS R R SR S E S+ G P +
Sbjct: 444 YKARDRSRSRSPNKARDH---SRSRSPNKARDRSR-SRSPSKERDHSQLGSPSKERDHRR 499
Query: 356 GKMASRRSEEKEA 368
+ S+ + +++
Sbjct: 500 SRSPSKERQCRQS 512
Score = 52.8 bits (125), Expect = 5e-07
Identities = 45/155 (29%), Positives = 76/155 (49%), Gaps = 18/155 (11%)
Query: 232 VAEKQEKRNQDRLRRREEREREERLSRRS--GSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
++ + + NQ R R + + R RRS GS+ R R RS +R SR+ SR R+
Sbjct: 262 MSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKG 321
Query: 290 L-------SRSRSRDRHR-RHRSRSRSHSRGH---RRASRDRSAKYK--FSRERASREES 336
+ S+SRS + + +++SR+ R H R S++RS + S+ER R S
Sbjct: 322 ILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 337 W---ESGRSERGPPDWRLESSNGKMASRRSEEKEA 368
ESGRS+ G P+ + + S + ++ + +
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRS 416
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/155 (32%), Positives = 67/155 (43%), Gaps = 22/155 (14%)
Query: 235 KQEKRNQDRLRRR---------EEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTS- 284
K + +NQ R RR +ER SR S S+ RD R S S + RS+S S
Sbjct: 337 KGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR-SSSKERDHRGSSSPRKESGRSQSGSP 395
Query: 285 RERRKLSRSRS----RDRHR-----RHRSRSRSHSRGHRR-ASRDRSAKYKFSRERASRE 334
++R SRSRS RDR R + R RSRS S R SR RS YK SR
Sbjct: 396 NKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRS-PYKARDRSRSRS 454
Query: 335 ESWESGRSERGPPDWRLESSNGKMASRRSEEKEAG 369
+ S P+ + S + S+ + + G
Sbjct: 455 PNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLG 489
Score = 43.5 bits (101), Expect = 3e-04
Identities = 43/138 (31%), Positives = 60/138 (43%), Gaps = 29/138 (21%)
Query: 226 DQLRKTVAEKQEKRNQDRLRRREE---------REREERLSR-----------RSGSRTR 265
D R K+ +R Q R +E ERE R SR RS S+ R
Sbjct: 520 DHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER 579
Query: 266 DRRRSRS----RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR-GHRRASRDR 320
+RR+SRS RD R RS ++ SR R+ + + H SRSR+ S+ G+ SR
Sbjct: 580 ERRQSRSSSEERDHSRSRS---PNKQSGYSRPRASSKEKAH-SRSRTPSKEGNHSQSRTS 635
Query: 321 SAKYKFSRERASREESWE 338
S + S+ R W+
Sbjct: 636 SKESDPSQSTVPRSPDWK 653
Score = 42.7 bits (99), Expect = 5e-04
Identities = 46/155 (29%), Positives = 69/155 (44%), Gaps = 11/155 (7%)
Query: 219 IQIREKLDQLRKTVAEKQEKRNQDRLRRREER----EREERLSRRSGSRTRDRRRSRSRD 274
I +EK D + + K + Q + RE+ E R+ + + TR R +S S+
Sbjct: 225 IPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284
Query: 275 RRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASRE 334
R RRSRS S++R SR RS R H SR+ SR R+ + ++ SR + +
Sbjct: 285 RSPRRSRSGSQKRTH-SRVRSHSWKRNH---SRARSR-TRKGILSQMGRHSQSRSHSKGK 339
Query: 335 ESWESGRSERG-PPDWRLESSNGKMASR-RSEEKE 367
+S RG +W S + S RS KE
Sbjct: 340 SQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKE 374
Score = 40.8 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 53/137 (38%), Gaps = 29/137 (21%)
Query: 238 KRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRER-----RKLSR 292
KRN R R R + ++ R S SR+ + +S+++ R RR RS + R R S
Sbjct: 308 KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSH 367
Query: 293 SRSRDRHRRHR-----------------------SRSRSHSRGHRRASRDRSAKYKFSRE 329
SRS + R HR SRSRS ++ R SR RS R
Sbjct: 368 SRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDR-SRSRSPYKARDRS 426
Query: 330 RASREESWESGRSERGP 346
R+ R P
Sbjct: 427 RSRSPNKARDCSRSRSP 443
Score = 35.8 bits (81), Expect = 0.063
Identities = 32/108 (29%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 252 REERLSRRSGSRTRDRRRSRSRDRR--RRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309
R + S+ S R RR + SR R RR SRS+ +R SR+ + R R H +R
Sbjct: 99 RTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSS---KRSPSRASTPGRIRTHGARPGMA 155
Query: 310 SRGHRRASRDRSAKYK-FSRERASREESWESGRSERGPPDWRLESSNG 356
SR S+ + ++ K + R R S E +S +R +G
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSG 203
Score = 32.3 bits (72), Expect = 0.70
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 3/117 (2%)
Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSR-STSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
S + R RSR R + R SR ST K S++ H+R + SR + G R
Sbjct: 69 STKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRG 128
Query: 316 ASRDRSAKYKFSRERASREESWESGRSER-GPPDWRLESSNGKMASR-RSEEKEAGE 370
+ + + + S R G + R P + + S GK R R+ +E +
Sbjct: 129 SRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSD 185
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 65.1 bits (157), Expect = 1e-10
Identities = 59/274 (21%), Positives = 112/274 (40%), Gaps = 15/274 (5%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
+RR L ++ E E+ + K ++ E E KL E+ E Q++
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL---EEEERREQQERREQQLRR 509
Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
E E+ R ++ + +EE +QQ R E L + ++RL +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ---- 565
Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
+++ + ++ R + +++E+R Q RL+R +E E+RL R R R R++R
Sbjct: 566 --RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER---REQRL 620
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS---AKYKFSRERASRE 334
+R R++L +S ++ R+ + R R +R R+ + + RE
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 335 ESWESGRSERGPPDWRLESSNGKMASRRSEEKEA 368
E E+ R++S K + E +A
Sbjct: 681 REQELAEEEQEQARERIKSRIPKWQWQLESEADA 714
Score = 58.9 bits (141), Expect = 7e-09
Identities = 60/264 (22%), Positives = 108/264 (40%), Gaps = 31/264 (11%)
Query: 108 LAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKK 167
L + +E++ E + ++ E E++ KL + ++L E +E Q+ + E+ +K+
Sbjct: 253 LRKEEEKLQEEEPQRQRELQEEEEQLRKL--ERQELRRERQEEEQQQQRLRREQQLRRKQ 310
Query: 168 EAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQ 227
E E QQ++ R +RR + L Q + Q
Sbjct: 311 EEERRE---------QQEERR-----------EQQERREQQEERREQQLRREQEERREQQ 350
Query: 228 LRKTVAEKQEKRNQDRLRRREERER-EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRE 286
LR+ E++E+R + +LRR +E ER E++L R R + R + RR ++ R +
Sbjct: 351 LRR---EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 287 RRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGP 346
RR+ R + R + R H + + + RE+ R + W E
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRD-WLKREEETE- 465
Query: 347 PDWRLESSNGKMASRRSEEKEAGE 370
R E K +R +E+E E
Sbjct: 466 ---RHEQERRKQQLKRDQEEERRE 486
Score = 56.6 bits (135), Expect = 3e-08
Identities = 72/327 (22%), Positives = 127/327 (38%), Gaps = 49/327 (14%)
Query: 76 KERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK 135
++RD F + E + R+ K RL E + + E +L + G+
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQ 1610
Query: 136 LLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
+ E+ + E +++L E E+ + ++E + ++ P Q+++ ++
Sbjct: 1611 QQLRQER---DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL------ 1661
Query: 196 YLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLR---------R 246
HD DR+ + L G Q + ++ RK E+Q+ R Q+R R R
Sbjct: 1662 ---RHDRDRKFREE-EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 247 REERER-------------EERLSRRS------------GSRTRDRRRSRSRDRRRRRSR 281
R+E ER +E+L R+ R + R + RDR+ R
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 282 STSRERRKLS-RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESG 340
+ER + RS+ DR R + R + + R KY++ E+ EE +
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRL 1837
Query: 341 RSERGPPDWRLESSNGKMASRRSEEKE 367
R ER +R E R EE+E
Sbjct: 1838 RQER-DRQYRAEEQFATQEKSRREEQE 1863
Score = 55.1 bits (131), Expect = 1e-07
Identities = 59/276 (21%), Positives = 115/276 (41%), Gaps = 29/276 (10%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILM 157
DRR E ++R ++ E + + + E +L EQ + +++ +
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER--ELAEGEEQSEKQERLEQRDRQRR 169
Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
+ E R +++ E E R + ++++L+ C+ H+ + F + L
Sbjct: 170 DEELWRQRQEWQEREERRA------EEEQLQSCKG-------HETEE-----FPDEEQL- 210
Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
+ RE L+ RK EKQ++R + + R +E E +E R + R + + +R+
Sbjct: 211 --RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQ 268
Query: 278 RRSRSTSRERRKLSRS---RSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASRE 334
R + + RKL R R R + + R R + R+ +R + + RE+ R
Sbjct: 269 RELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 335 ESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
E E R ++ R + + RR +E+E E
Sbjct: 329 EQQEERREQQLR---REQEERREQQLRREQEEERRE 361
Score = 55.1 bits (131), Expect = 1e-07
Identities = 58/275 (21%), Positives = 111/275 (40%), Gaps = 10/275 (3%)
Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
RR + ++ E + E E + +++ EE L + E+ Q++ +
Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRD 479
Query: 159 VEKVRAKK-KEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLG 217
E+ R ++ + EEE R QQ + E L + + RL +
Sbjct: 480 QEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQ--- 536
Query: 218 FIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRR 277
Q+R + ++ R+ + +++E++ ++ RR + +RE+ RR R+ R + R +R
Sbjct: 537 --QLRREQEERREQLLKREEEKRLEQERREQRLKREQE-ERRDQLLKREEERRQQRLKRE 593
Query: 278 RRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESW 337
+ R R +R+ R RR + R RR +S + + R++ R E
Sbjct: 594 QEERLEQRLKRE-EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 338 E--SGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
E R +R + RLE + E+E E
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Score = 53.9 bits (128), Expect = 2e-07
Identities = 59/251 (23%), Positives = 109/251 (43%), Gaps = 38/251 (15%)
Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
RR E +K L E Q+ + E+ + EE L + EQ + +K L E
Sbjct: 1440 RRQERERKFLEEEQQ-------LRQERHRKFREEEQLLQEREEQ--QLHRQERDRKFLEE 1490
Query: 159 VEKVRAKKKEA---EEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
+++R ++++ E+E R+ P F +++ + LH R+
Sbjct: 1491 EQQLRRQERDRKFREQELRSQEPERKFLEEEQQ----------LHRQQRQRK-------- 1532
Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR--RRSRSR 273
F+Q + QLR+ +Q ++++DR R EE+ R+ER ++ + RDR R +
Sbjct: 1533 --FLQEEQ---QLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK 1587
Query: 274 DRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASR 333
RR+ + R + ++L R + + R+ R R + R+ ++ R+R
Sbjct: 1588 VRRQEQERKFMEDEQQLRRQEGQQQLRQERDR-KFREDEQLLQEREEQQLHRQERDRKFL 1646
Query: 334 EESWESGRSER 344
EE + R ER
Sbjct: 1647 EEEPQLRRQER 1657
Score = 52.4 bits (124), Expect = 7e-07
Identities = 70/309 (22%), Positives = 124/309 (40%), Gaps = 58/309 (18%)
Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
R E +++L + +EE E + +++ EE L K E+ + + Q+ +E
Sbjct: 540 REQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE 599
Query: 159 -------VEKV--------RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND 203
VE++ R K++E EEE R + S Q+++ + L +
Sbjct: 600 QRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQ------QQLRREQQE 653
Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRR---- 259
RR + L + E+L+Q K E +E+R + L E+ + ER+ R
Sbjct: 654 RR-------EQRLKREEEEERLEQRLKR--EHEEERREQELAEEEQEQARERIKSRIPKW 704
Query: 260 --------SGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSR 311
+++ R R ++ +RRR + RR+ S + ++ R HR + R
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 312 --------GHRRASRDR---SAK--YKFSRERASREESWESGRSERGPPDWRLESSNGKM 358
++ R R SA+ + RER R E + R +R P+ E +
Sbjct: 765 RDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-REQRFLPE--EEEKEQRR 821
Query: 359 ASRRSEEKE 367
RR EKE
Sbjct: 822 RQRREREKE 830
Score = 51.2 bits (121), Expect = 1e-06
Identities = 62/301 (20%), Positives = 118/301 (39%), Gaps = 18/301 (5%)
Query: 72 EIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEE--ISAEVSAKAEKVHEL 129
E ++R+L E + + LE R EL ++R E Q++ + E + ++ E
Sbjct: 263 EEPQRQRELQEEEEQLRKLE--------RQELRRERQEEEQQQQRLRREQQLRRKQEEER 314
Query: 130 NEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRV 189
E+ + + E+ + E Q + E+ + + +EE R Q+++ R
Sbjct: 315 REQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 190 CEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREE 249
++ + R + L Q + QLR+ E+Q +R Q R +EE
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQEE 431
Query: 250 REREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSH 309
E++ + + R + RD +R + E+ + + RD+ R R
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 310 SRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAG 369
RR ++R + + RE+ R E R +R + RL+ R E++E
Sbjct: 492 EEEERREQQER-REQQLRREQEERREQ----RLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 370 E 370
E
Sbjct: 547 E 547
Score = 51.2 bits (121), Expect = 1e-06
Identities = 61/284 (21%), Positives = 114/284 (40%), Gaps = 27/284 (9%)
Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
E ++ E K R+ + Q ++ +E A+ KV+ + + EQ E +
Sbjct: 689 EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQ---EEKRRRRESE 745
Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKL-RVCEVCSAYLGLHDNDRRLADHFGGKL 214
L E+ RA +++ EEE R ++K R + SA L + R
Sbjct: 746 LQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQ-------- 797
Query: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREERE-----REERLSRRS-GSRTRDRR 268
++ E+ + ++ + E++EK + R RR E+E EE+L RR + ++
Sbjct: 798 ----LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853
Query: 269 RSRSRDRRRRRSRSTSRERR---KLSRSRSRDRHRRHRSRSRSHS--RGHRRASRDRSAK 323
D+ RRRS+ R+++ +L R R RH + + + + +
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Query: 324 YKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
+ RE+ R+E R E + + RR +E+E
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Score = 50.8 bits (120), Expect = 2e-06
Identities = 56/282 (19%), Positives = 111/282 (39%), Gaps = 26/282 (9%)
Query: 91 ESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGA----- 145
E +AE + ++E ++ ++ E+ + ++ E E A+ EQL +
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREER----RAEEEQLQSCKGHE 200
Query: 146 -EGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDR 204
E DE Q E+ ++R K +E +++ R FQ+++ + E L +
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEK--EWRKRETVLRKEEE 258
Query: 205 RLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRT 264
+L + E+ + R+ E+++ R +R R ER+ EE+ +R
Sbjct: 259 KLQE--------------EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQ 304
Query: 265 RDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324
+ RR+ R ++ R +ERR+ R + RR + R + R +
Sbjct: 305 QLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Query: 325 KFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEK 366
+ +E RE+ + R R E + R E++
Sbjct: 365 RREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406
Score = 50.1 bits (118), Expect = 3e-06
Identities = 57/272 (20%), Positives = 111/272 (40%), Gaps = 22/272 (8%)
Query: 102 ELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKA--EQLGAEGNVDESQKILMEV 159
E K+R E +++ E + E+ L EE K + Q + + + ++ L+
Sbjct: 977 EPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLRE 1036
Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFI 219
E+ + + +E E +YR ++Q LG RR + + +
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQ----------LLGEERETRRRQEL--ERQYRKEE 1084
Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
+++++ +QL + EK +R Q+R R+ E E ++ + R++RR + +R+ R
Sbjct: 1085 ELQQEEEQLLREEPEK--RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142
Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSR----SRSHSRGHRRASRDRSAKYKFSRERASREE 335
+E +L R R R+ R + + R+ K + RER REE
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 336 SWESGRSERGPPDWRLESSNGKMASRRSEEKE 367
E + ++ +R E + + EKE
Sbjct: 1203 --EELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232
Score = 50.1 bits (118), Expect = 3e-06
Identities = 72/322 (22%), Positives = 130/322 (40%), Gaps = 56/322 (17%)
Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLA-----KAEQLGAEGNVD 150
E +RR + R +E++ E +A++ ++E +LL K + +
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFR 1339
Query: 151 ESQKILMEVEKVRAKKKEA-----EEEYRNSMPASSF--QQQKLRVCEVCSAYLG----- 198
E +++L E E+ +++E EEE R+ F ++Q+LR E +L
Sbjct: 1340 EEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Query: 199 -LHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRR--------REE 249
+ +++L K Q+ + ++ RK E+Q+ R Q+R R+ R+E
Sbjct: 1400 RCQEREQQLRQDRDRKFREEEQQLSRQ-ERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458
Query: 250 RER---------EERLSRRSGSRTRDRR--------RSRSRDRRRRRSRSTSRERRKLSR 292
R R +ER ++ + RDR+ R + RDR+ R S+E +
Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518
Query: 293 SRSRDRHRRHRSRS--------RSHSRGHRRASRDRSAKYKFSRERASREESWESGRSER 344
+ HR+ R R R RG +R +DR K++ + E + R ER
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQR-RQDRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 345 GPPDWRLESSNGKMASRRSEEK 366
D + K+ + E K
Sbjct: 1578 ---DRKFRLEEQKVRRQEQERK 1596
Score = 48.9 bits (115), Expect = 7e-06
Identities = 50/226 (22%), Positives = 97/226 (42%), Gaps = 28/226 (12%)
Query: 139 KAEQLGAEGNVDESQKILMEVEKV---RAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSA 195
+ QL AE Q+ L E E+ R +++E E+E + Q+++ R ++
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE-RAQQLQEE 852
Query: 196 YLGLHDNDRR---------------LADHFGGKLHLGFIQ--IREKLDQLRKTVAEKQEK 238
GL ++ R L + + H + + ++E+L + ++ + E++E+
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912
Query: 239 --RNQDRLRRREERER----EERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSR 292
R + RRR+E+ER EE+L + R+ R R R R R+ R + ++K +
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 293 SRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWE 338
+ +R R R ++ + RE+ R+E WE
Sbjct: 973 LLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE-WE 1017
Score = 48.5 bits (114), Expect = 9e-06
Identities = 61/270 (22%), Positives = 111/270 (41%), Gaps = 45/270 (16%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEV 159
R E K+R E + + E + E+ L EE K + E+ E E+
Sbjct: 1155 REEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEE---------EL 1205
Query: 160 EKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND--RRLADHFGGKLHLG 217
++ + K++ +E+ R+ + ++ +K Y +N+ R+L D
Sbjct: 1206 QRQKRKQRYRDEDQRSDLKWQ-WEPEKENAVRDNKVYCKGRENEQFRQLEDS-------- 1256
Query: 218 FIQIREKLDQ--LRKTVAEKQEKRNQDRLRRREERER----EERLSR--RSGSRTRDR-- 267
Q+R++ Q L+ + E+QE+ + RR ++R+R EE+L R + ++ RDR
Sbjct: 1257 --QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS 1314
Query: 268 -------RRSRSRDRRRRRSRSTSRERRKLSRSRS------RDRHRRHRSRSRSHSRGHR 314
R R RRR+ + RE +L + R ++R R+ R H R
Sbjct: 1315 QEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGR 1374
Query: 315 RASRDRSAKYKFSRERASREESWESGRSER 344
+ + + RER +E + ER
Sbjct: 1375 KFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Score = 48.1 bits (113), Expect = 1e-05
Identities = 38/153 (24%), Positives = 69/153 (45%), Gaps = 9/153 (5%)
Query: 220 QIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRR 279
Q RE+ D++ + EK+ ++ + LR+ EE+ +EE R+ + + + + + RR
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRR 288
Query: 280 SRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWES 339
R E ++ R R + RR + R + RR ++R + + RE+ R E
Sbjct: 289 ER--QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE---- 342
Query: 340 GRSERGPPDWRLESSNGKMAS--RRSEEKEAGE 370
+ ER R E + RR +E+E E
Sbjct: 343 -QEERREQQLRREQEEERREQQLRREQEEERRE 374
Score = 47.8 bits (112), Expect = 2e-05
Identities = 54/271 (19%), Positives = 104/271 (38%), Gaps = 38/271 (14%)
Query: 102 ELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEK 161
E +++L QEE E + E+ E E+ L + +QL E + Q++ E +
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQ---QLRREQQLRREQQLRREQQLRREQQL 401
Query: 162 VRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQI 221
R ++ E++ R QQ + Q
Sbjct: 402 RREQQLRREQQLRREQQLRREQQLRRE-------------------------------QE 430
Query: 222 REKLDQLRKTVAEKQEKR-NQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRS 280
E+ +Q K E++E+R +++ RR+ +REE R R + + + + RR R
Sbjct: 431 EERHEQ--KHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 281 RSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESG 340
E R+ + R R++ R R R R+ +R + S ++ RE+
Sbjct: 489 LKLEEEERREQQER-REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 341 RSERGPPDWRLESSNGKMASRRSEEKEAGEI 371
+ + + RLE + +R +E+ ++
Sbjct: 548 QLLKREEEKRLEQERREQRLKREQEERRDQL 578
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/240 (20%), Positives = 93/240 (38%), Gaps = 45/240 (18%)
Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQ---LGAEGNVDESQKI 155
R T AK L QE++ E E+ EL E + + EQ E + + ++
Sbjct: 886 RHTLYAKPAL---QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQ 942
Query: 156 LMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLH 215
L+ E+ + +++E E +YR ++Q L
Sbjct: 943 LLREEREKRRRQERERQYRKDKKLQQKEEQLLG--------------------------- 975
Query: 216 LGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDR 275
E+ ++ R+ EK+ + ++ + E+ REER RR R R+ R +D
Sbjct: 976 -------EEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR---RQEWERQYRKKDE 1025
Query: 276 RRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREE 335
++ RE R+ + R ++R R++R + +R + + ER R+E
Sbjct: 1026 LQQEEEQLLREERE--KRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE 1083
Score = 45.8 bits (107), Expect = 6e-05
Identities = 55/264 (20%), Positives = 108/264 (40%), Gaps = 50/264 (18%)
Query: 96 ECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKI 155
E ++R ++R E Q E + E+ +L EE E + E Q+
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEE-------------EDGLQEDQER 862
Query: 156 LMEVEKVRAKK-----KEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHF 210
E+ R +K +E + R+++ A Q++LR +++L
Sbjct: 863 RRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLR-------------KEQQLLQEE 909
Query: 211 GGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRL-------RRREEREREERLSRRSGSR 263
+L + R + +Q R+ E+Q ++ +++L RRR+ERER+ R ++ +
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969
Query: 264 TR-------DRRRSRSRDRRRRRSRSTSRERRKLSRS-----RSRDRHRRHRSRSRSHSR 311
++RR + R+++ R +E +L R R ++ R++R +
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
Query: 312 GHRRASRDRSAKYKFSRERASREE 335
+ +R + RER REE
Sbjct: 1030 EEQLLREEREKRRLQERERQYREE 1053
Score = 45.8 bits (107), Expect = 6e-05
Identities = 71/339 (20%), Positives = 133/339 (39%), Gaps = 52/339 (15%)
Query: 67 LRADYEIASKERDLFF---ELDAMDHLESFIAECDR--RTELAKKRLAETQEEISAEVSA 121
L + ++ +ERD F EL + + F+ E + R + +K L E Q+
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQ------LR 1541
Query: 122 KAEKVHELNEEIGKLLAKAEQLGAE------GNVDESQKILMEVEKVRAKKKEA-----E 170
+ E+ + ++ + + EQL E + +K +E +KVR +++E E
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 171 EEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIR--EKLDQL 228
++ R +Q++ R ++++ L + +LH + E+ QL
Sbjct: 1602 QQLRRQEGQQQLRQERDRK---------FREDEQLLQEREEQQLHRQERDRKFLEEEPQL 1652
Query: 229 RKTVAEKQEKRNQDRL---------------RRREEREREERLSRRSGSRTRDRRR--SR 271
R+ E+Q + ++DR RR+ER+R+ R + R R+
Sbjct: 1653 RRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 272 SRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERA 331
+ RR+ RE +L + +++ RR + R R+ + R+R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 332 SREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGE 370
REE E R ER R + S+ K +E E
Sbjct: 1773 FREE--EQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Score = 44.7 bits (104), Expect = 1e-04
Identities = 50/248 (20%), Positives = 96/248 (38%), Gaps = 28/248 (11%)
Query: 100 RTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGK--LLAKAEQLGAEGNVDESQKILM 157
R E K+R E + + + + E+ L EE K L + Q E + + ++ L+
Sbjct: 1005 REEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVC----------EVCSAYLGLHDNDRRLA 207
E+ +++E E +YR ++Q LR C L + +L
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL- 1123
Query: 208 DHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDR 267
+RE+ ++ R+ E+Q + ++ + E+ REE RR R
Sbjct: 1124 -------------LREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 268 RRSRSRDRRRRRSRSTSRERRKLSRSRS-RDRHRRHRSRSRSHSRGHRRASRDRSAKYKF 326
R + + +E+R+ R R R+ R + + R + S D +++
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS-DLKWQWEP 1229
Query: 327 SRERASRE 334
+E A R+
Sbjct: 1230 EKENAVRD 1237
Score = 44.7 bits (104), Expect = 1e-04
Identities = 49/226 (21%), Positives = 94/226 (41%), Gaps = 24/226 (10%)
Query: 99 RRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILME 158
RR E +K L E Q+ E+ K + +L +E + EQL + E + ++E
Sbjct: 1701 RRQERERKFLQEEQQLRRQELERKFREEEQLRQE-----TEQEQLRRQ----ERYRKILE 1751
Query: 159 VEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGF 218
E++R +++E ++ R F++++ E L ++DR+ + +
Sbjct: 1752 EEQLRPEREE--QQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREE 1809
Query: 219 IQIREKL---------DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRR 269
Q+R + +QL+ E++ ++ +DR R EE+ + SRR
Sbjct: 1810 QQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869
Query: 270 SRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRR 315
+ R R R+ R R++ + RHR+ +GH R
Sbjct: 1870 QKRRQERERKLREEHIRRQQ----KEEQRHRQVGEIKSQEGKGHGR 1911
Score = 43.9 bits (102), Expect = 2e-04
Identities = 59/339 (17%), Positives = 113/339 (33%), Gaps = 80/339 (23%)
Query: 68 RADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVH 127
R + +ER E + E + E E +++ E Q E+ + E++
Sbjct: 1038 REKRRLQERERQYREEEELQQEEEQLLGE---ERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 128 ELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKL 187
E + + Q E + + ++ L+ E+ + +++E E +YR ++Q L
Sbjct: 1095 REEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLL 1154
Query: 188 RVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRR 247
R + ++R +L + + E + + + E+QEKR Q+R R+
Sbjct: 1155 R-----------EEPEKRRRQ----ELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199
Query: 248 EEREREERLSRRSGSRTRDRR--------------------------------------- 268
E E +R R+ R D+R
Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 269 -------------RSRSRDRRRRRSRSTSR----------ERRKLSRSRSRDRHRRHRSR 305
+ RDR + R R R ER + ++ RDR + +
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319
Query: 306 SRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSER 344
R +R ++ K++ + E R ER
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQER 1358
Score = 43.1 bits (100), Expect = 4e-04
Identities = 50/252 (19%), Positives = 92/252 (36%), Gaps = 38/252 (15%)
Query: 98 DRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAE-QLGAEGNVDESQKIL 156
+ E ++RL EE E E+ + E I + K + QL +E + +S K+
Sbjct: 662 EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS-KVY 720
Query: 157 MEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHL 216
K +++ E+E + S Q Q+ + H
Sbjct: 721 SRPRKQEGQRRRQEQEEKRRRRESELQWQEEE------------------------RAHR 756
Query: 217 GFIQIREKLDQLRKTVAEKQEKRNQDRLRRR----EEREREERLSRRSGSRTRDRRRSRS 272
+ ++ D + AE++ +R + RL R E+RER+ R R R
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRS--------RSRSHSRGHRRASRDRSAKY 324
+++RRR+ R +E + L R R + + R + RD+ ++
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 325 KFSRERASREES 336
+ ER R +
Sbjct: 877 QLEEERKRRRHT 888
Score = 37.7 bits (86), Expect = 0.017
Identities = 55/251 (21%), Positives = 103/251 (41%), Gaps = 32/251 (12%)
Query: 70 DYEIASKERDLFF-----ELDAMDHLESFIAECD--RRTELAKKRLAETQ--EEISAEVS 120
+ ++ +ERD F +L + F+ E RR EL +K E Q +E E
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 121 AKAEKVHELNEEIGKLLAKAEQLGAEGNVD----ESQKILMEVEKVRAKKKEAEEEYRNS 176
+ E+ ++ EE + EQ D E +++ E E+ + + +E++ ++R
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 177 MPA-SSFQQQKLRVCEVCSAY------LGLHDNDRRLADHFGGKLHLGFIQIREKLDQLR 229
++Q+LR + Y L L + ++RL + + E+
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQY-----RAEEQFATQE 1855
Query: 230 KTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRK 289
K+ E+QE ++ +RR+ERER+ R RR+ + R R+ S+E +
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLR-------EEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
Query: 290 LSRSRSRDRHR 300
R H+
Sbjct: 1909 HGRLLEPGTHQ 1919
Score = 36.2 bits (82), Expect = 0.049
Identities = 36/177 (20%), Positives = 64/177 (36%), Gaps = 13/177 (7%)
Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLS 257
GL + R D GK L +Q R + + R+ ++ + RRR++R+ +ER
Sbjct: 94 GLDEEKRARCD---GKESL--LQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQEREL 148
Query: 258 RRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRAS 317
++ + R RD R+RR R+R++ R + H
Sbjct: 149 AEGEEQSEKQERLEQRD-RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 318 RDRSAKYKFSRERASREESWESGR-------SERGPPDWRLESSNGKMASRRSEEKE 367
+ R REE + R E +WR + + + +E+E
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Score = 34.3 bits (77), Expect = 0.18
Identities = 45/255 (17%), Positives = 96/255 (37%), Gaps = 14/255 (5%)
Query: 122 KAEKVHELNEEIGKLLAKAEQLGAEGNVDE------SQKILMEVEKVRAKKKEA-----E 170
+ E+ +L + + + EQL EG + +K E +++R +++E E
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 171 EEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRK 230
++ R F++++ E L + R++ + + Q+R Q R
Sbjct: 1714 QQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR---QERD 1770
Query: 231 TVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKL 290
++E+ Q+R ++ + +R R ++R + R ++R E+ +L
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 291 SRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWR 350
R R R R + SR + E+ R+E R E +
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQK 1890
Query: 351 LESSNGKMASRRSEE 365
E + ++ +S+E
Sbjct: 1891 EEQRHRQVGEIKSQE 1905
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 64.7 bits (156), Expect = 1e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 234 EKQEKRNQDRLRRREEREREERLSRRSGS----RTRDRRRSRSRDRRRRRSRSTSRERRK 289
E K+ +R R + R R S RS S R+R R RSRS + RSRS+SRER +
Sbjct: 191 EDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 290 LSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDW 349
S+SR R HR S R + +S K SR R+S + R+ P+
Sbjct: 251 SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPES 310
Query: 350 RLESSNGK 357
++ N K
Sbjct: 311 QVIGENTK 318
Score = 55.8 bits (133), Expect = 6e-08
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 8/173 (4%)
Query: 198 GLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-L 256
G +D R + GK +G I ++++ E+ E + + + E+ + ++ L
Sbjct: 122 GEYDEFGRKKKKYRGKA-VGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADL 180
Query: 257 SRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHR-RHRSRSRSHSRGHRR 315
S+ + + + ++ + RR RS+S S R SRS S R R RSRSRS S
Sbjct: 181 SKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQ-- 238
Query: 316 ASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEA 368
SR RS+ + SR R S+ S S RS RG R S + +S K +
Sbjct: 239 -SRSRSSSRERSRSRGSKSRS--SSRSHRGSSSPRKRSYSSSSSSPERNRKRS 288
Score = 49.3 bits (116), Expect = 6e-06
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 3/93 (3%)
Query: 229 RKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERR 288
R + R++ R R + R S R SR+R S+SR R S+S +R
Sbjct: 216 RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRG---SKSRSSSRSHRGSSSPRKR 272
Query: 289 KLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321
S S S R RSRSRS S G R+ R RS
Sbjct: 273 SYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRS 305
Score = 42.4 bits (98), Expect = 7e-04
Identities = 47/215 (21%), Positives = 83/215 (38%), Gaps = 48/215 (22%)
Query: 84 LDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQL 143
L ++ ES E D +L+K +L E ++E A++S L
Sbjct: 145 LKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKY-------------------NL 185
Query: 144 GAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDND 203
A D ++K + +++ + R+S P+SS + + R S+
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSS-------- 237
Query: 204 RRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR 263
Q R + ++ + + R+ R R R+ S S S
Sbjct: 238 ----------------QSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSP 281
Query: 264 TRDRRRSRSR-----DRRRRRSRSTSRERRKLSRS 293
R+R+RSRSR DR++RR+RS S E + + +
Sbjct: 282 ERNRKRSRSRSSSSGDRKKRRTRSRSPESQVIGEN 316
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,898,447
Number of Sequences: 37866
Number of extensions: 573334
Number of successful extensions: 20896
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 481
Number of HSP's successfully gapped in prelim test: 622
Number of HSP's that attempted gapping in prelim test: 5804
Number of HSP's gapped (non-prelim): 5608
length of query: 371
length of database: 18,247,518
effective HSP length: 104
effective length of query: 267
effective length of database: 14,309,454
effective search space: 3820624218
effective search space used: 3820624218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.