BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|41349454 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] (382 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|41349454 proline arginine-rich end leucine-rich repeat protei... 794 0.0 gi|4506041 proline arginine-rich end leucine-rich repeat protein... 794 0.0 gi|5901992 keratocan [Homo sapiens] 368 e-102 gi|71040111 fibromodulin precursor [Homo sapiens] 265 4e-71 gi|4826876 osteomodulin [Homo sapiens] 248 6e-66 gi|4505047 lumican precursor [Homo sapiens] 238 9e-63 gi|45505137 podocan [Homo sapiens] 149 5e-36 gi|19743846 decorin isoform a preproprotein [Homo sapiens] 147 1e-35 gi|4503271 decorin isoform a preproprotein [Homo sapiens] 147 1e-35 gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 138 9e-33 gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 138 9e-33 gi|41350214 asporin [Homo sapiens] 137 2e-32 gi|4502403 biglycan preproprotein [Homo sapiens] 136 3e-32 gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 123 2e-28 gi|225579152 insulin-like growth factor binding protein, acid la... 110 2e-24 gi|4826772 insulin-like growth factor binding protein, acid labi... 110 2e-24 gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 110 3e-24 gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 100 2e-21 gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo... 99 5e-21 gi|20302168 toll-like receptor 8 [Homo sapiens] 99 6e-21 gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 99 6e-21 gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 99 6e-21 gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 99 6e-21 gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 98 1e-20 gi|153251229 chondroadherin precursor [Homo sapiens] 96 5e-20 gi|76880480 hypothetical protein LOC9865 [Homo sapiens] 95 1e-19 gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo ... 92 6e-19 gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 92 8e-19 gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 92 1e-18 gi|7657419 opticin precursor [Homo sapiens] 91 2e-18 >gi|41349454 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 794 bits (2051), Expect = 0.0 Identities = 382/382 (100%), Positives = 382/382 (100%) Query: 1 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP 60 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP Sbjct: 1 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP 60 Query: 61 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE 120 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE Sbjct: 61 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE 120 Query: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ 180 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ Sbjct: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ 180 Query: 181 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV 240 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV Sbjct: 181 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV 240 Query: 241 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH Sbjct: 241 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300 Query: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360 Query: 361 YLKPPIPLDLMMCFRLLQSVVI 382 YLKPPIPLDLMMCFRLLQSVVI Sbjct: 361 YLKPPIPLDLMMCFRLLQSVVI 382 >gi|4506041 proline arginine-rich end leucine-rich repeat protein precursor [Homo sapiens] Length = 382 Score = 794 bits (2051), Expect = 0.0 Identities = 382/382 (100%), Positives = 382/382 (100%) Query: 1 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP 60 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP Sbjct: 1 MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPP 60 Query: 61 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE 120 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE Sbjct: 61 PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVE 120 Query: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ 180 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ Sbjct: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQ 180 Query: 181 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV 240 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV Sbjct: 181 NHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV 240 Query: 241 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH Sbjct: 241 PTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSH 300 Query: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN Sbjct: 301 NRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGN 360 Query: 361 YLKPPIPLDLMMCFRLLQSVVI 382 YLKPPIPLDLMMCFRLLQSVVI Sbjct: 361 YLKPPIPLDLMMCFRLLQSVVI 382 >gi|5901992 keratocan [Homo sapiens] Length = 352 Score = 368 bits (945), Expect = e-102 Identities = 177/313 (56%), Positives = 235/313 (75%), Gaps = 3/313 (0%) Query: 72 DCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWI 131 +CP EC+CPP FP+ALYC++R L+++P IP RI YLYLQNN I +P + F+NAT LRWI Sbjct: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100 Query: 132 NLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPG 189 NL+ N+I I++ L +L L+FL++E N+LEEVPS LPR+LEQL+L++N +SRIP G Sbjct: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160 Query: 190 VFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYL 249 FS LENL LLDLQ+N+L D F+ DTF GLKNLMQLN+A N LR MPPR+P QL+L Sbjct: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220 Query: 250 DSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAI 309 D+N IE IP YF P +AF+RLN+NKL+D GLP F++S++L L LSHN+++ VP I Sbjct: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280 Query: 310 NNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369 + L+HL+L++N I+ +N + ICP+ + + S PHLRYLRLDGN +KPPIP+ Sbjct: 281 SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDS-FSYGPHLRYLRLDGNEIKPPIPMA 339 Query: 370 LMMCFRLLQSVVI 382 LM CFRLLQ+V+I Sbjct: 340 LMTCFRLLQAVII 352 >gi|71040111 fibromodulin precursor [Homo sapiens] Length = 376 Score = 265 bits (678), Expect = 4e-71 Identities = 145/352 (41%), Positives = 207/352 (58%), Gaps = 29/352 (8%) Query: 44 PSFPQPDEPAEP----TDLPP------PLPPGPPSIFPDCPRECYCPPDFPSALYCDSRN 93 P P P E EP D P P PP P DCP+EC CPP+FP+A+YCD+RN Sbjct: 41 PYDPYPYETYEPYPYGVDEGPAYTYGSPSPPDPR----DCPQECDCPPNFPTAMYCDNRN 96 Query: 94 LRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIR--KIDQRVLEKLPG 151 L+ +P +P R+ Y+Y QNN IT + F NATGL WI L N+I K+ ++V KL Sbjct: 97 LKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWIALHGNQITSDKVGRKVFSKLRH 156 Query: 152 LVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGV 211 L LY++ N L +P LPR+L +L L N ISR+P LENL L LQHN + + Sbjct: 157 LERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNNALEGLENLTALYLQHNEIQE-- 214 Query: 212 FKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFI 271 + GL++L+ L+L++N LRK+P +P+A+ QLY++ N + T+P+ YF+ P L ++ Sbjct: 215 -VGSSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYMEHNNVYTVPDSYFRGAPKLLYV 273 Query: 272 RLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQI 331 RL++N LT+ GL N+FN S+LL L LS+N++ +P +N LE+LYL N I + + + Sbjct: 274 RLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPVNTNLENLYLQGNRINEFSISSF 333 Query: 332 CPNDLVAFHDFSSDLENVPHLRYLRLDGNYLK-PPIPLDLMMCFRLLQSVVI 382 C D+ N L+ LRLDGN +K +P D +C RL + I Sbjct: 334 CT---------VVDVVNFSKLQVLRLDGNEIKRSAMPADAPLCLRLASLIEI 376 >gi|4826876 osteomodulin [Homo sapiens] Length = 421 Score = 248 bits (633), Expect = 6e-66 Identities = 134/311 (43%), Positives = 188/311 (60%), Gaps = 15/311 (4%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWIN 132 C EC+CP +FPS++YCD+R L+ +P IP I LYLQ N I + SF NAT L+ IN Sbjct: 62 CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121 Query: 133 LDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGV 190 L +N+I+ KID V KLP L+ L++E N LEE P LP++LE+L L N IS++ Sbjct: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNA 181 Query: 191 FSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLD 250 L NL +LDL +N L D + K F ++ LMQLNL N L MPP +P+++ L L+ Sbjct: 182 MDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLE 241 Query: 251 SNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAIN 310 +N I +IP YF P L +R+++NKL D +P N FN+ N++ L + HN++ I Sbjct: 242 NNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIP 299 Query: 311 NRLEHLYLNNNSIEKINGTQICPN-DLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369 LEHLYL NN IEK+N T +CP+ D + +H HL Y+R+D N LK PI Sbjct: 300 RNLEHLYLQNNEIEKMNLTVMCPSIDPLHYH----------HLTYIRVDQNKLKEPISSY 349 Query: 370 LMMCFRLLQSV 380 + CF + ++ Sbjct: 350 IFFCFPHIHTI 360 >gi|4505047 lumican precursor [Homo sapiens] Length = 338 Score = 238 bits (606), Expect = 9e-63 Identities = 127/315 (40%), Positives = 193/315 (61%), Gaps = 15/315 (4%) Query: 71 PDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRW 130 P+C EC CP +PSA+YCD L+ VP++PP I YLYL+NN I + ++F+N T L+W Sbjct: 35 PNCAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQW 94 Query: 131 INLDNNRIR--KIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188 + LD+N + KI RV KL L L++ N L E LP++LE L+L+ N I+++ Sbjct: 95 LILDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL-- 152 Query: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248 G F L NL + LQHNRL + F GLK+L L+L+ N + ++P +P ++ LY Sbjct: 153 GSFEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLY 211 Query: 249 LDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPA 308 LD+NKI IP+ YFK F L ++RL++N+L D G+P NSFN+S+L+ L LS+N++ ++P Sbjct: 212 LDNNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPT 271 Query: 309 INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL-KPPIP 367 +N LE+ YL N +EK D+ +F L + +++LRLDGN + + +P Sbjct: 272 VNENLENYYLEVNQLEKF--------DIKSFCKILGPL-SYSKIKHLRLDGNRISETSLP 322 Query: 368 LDLMMCFRLLQSVVI 382 D+ C R+ V + Sbjct: 323 PDMYECLRVANEVTL 337 >gi|45505137 podocan [Homo sapiens] Length = 661 Score = 149 bits (375), Expect = 5e-36 Identities = 103/324 (31%), Positives = 162/324 (50%), Gaps = 24/324 (7%) Query: 47 PQPDEPAE--PTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPR 103 P+ +E AE P + P PGP CPR+C C + + C +LR+ P +P Sbjct: 88 PEENEFAEEEPVLVLSPEEPGPGPAAVSCPRDCACSQE--GVVDCGGIDLREFPGDLPEH 145 Query: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRI--RKIDQRVLEKLPGLVFLYMEKNQ 161 ++L LQNN + ++ E L +NL NNR+ R + ++ E L L +LY+ N+ Sbjct: 146 TNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNK 205 Query: 162 LEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLK 221 L P LP L + + N++++I F + NL + L +N+L+D + F+G Sbjct: 206 LTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSS 265 Query: 222 NLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDR 281 N+ L L+ N LR +P +P A+++L+L +NK+E IP G F +L + L N LTD Sbjct: 266 NVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDE 325 Query: 282 GLPKNSF-NISNLLVLHLSHNRISSVPA-INNRLEHLYLNNNSIEKINGTQICPNDLVAF 339 GL +F +S+L L LS N +S VPA + L L+L N+I ++ + P Sbjct: 326 GLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTP------ 379 Query: 340 HDFSSDLENVPHLRYLRLDGNYLK 363 + L YL L N L+ Sbjct: 380 ---------IRSLEYLLLHSNQLR 394 Score = 108 bits (270), Expect = 8e-24 Identities = 94/352 (26%), Positives = 150/352 (42%), Gaps = 69/352 (19%) Query: 78 YCPPDFPSALYCDSRNLRKVPVIPP-------RIHYLYLQNNFITE--LPVESFQNATGL 128 + P P ALY K+ IPP + LYLQNN++T+ L E+F + L Sbjct: 279 HVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSL 338 Query: 129 RWINLDNNR---------------------IRKIDQRVLEKLPGLVFLYMEKNQLEE--- 164 +++L +N IR +D VL + L +L + NQL E Sbjct: 339 EYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGI 398 Query: 165 -----------------------VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLD 201 VPS LPR + L + N I+ I F+ L L+ Sbjct: 399 HPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELN 458 Query: 202 LQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGY 261 L +NR++ D F L+ L L+L+ N L +PP +P +H L + N++ + G Sbjct: 459 LSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGA 518 Query: 262 FKSFPNLAFIRLNYNKLTDRGL-PKNSFNISNLLVLHLSHNRISSVP-AINNRLEHLYLN 319 L + L N+L R L P+ ++++L +L ++ N+++ +P + LE+LYL Sbjct: 519 LVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQ 578 Query: 320 NNSIEKI--NGTQICPNDLVAFHDFS---------SDLENVPHLRYLRLDGN 360 NN I + N PN F F+ S + HL+ L ++GN Sbjct: 579 NNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGN 630 Score = 107 bits (268), Expect = 1e-23 Identities = 72/225 (32%), Positives = 117/225 (52%), Gaps = 4/225 (1%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQ 143 L S LR VP +PP ++ L+L+NN + ++P +F + LR + L NN + +D Sbjct: 270 LILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDN 329 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQ 203 KL L +L + N L VP+ LPR+L L L +N I + V + + +L L L Sbjct: 330 ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLH 389 Query: 204 HNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFK 263 N+L + P F GLK L ++L +N L ++P +P + L + N+I I F Sbjct: 390 SNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFA 449 Query: 264 SFPNLAFIRLNYNKLTDRGLPKNSFNISNLL-VLHLSHNRISSVP 307 + L + L+YN++T + +++F LL L LS NR+ ++P Sbjct: 450 TTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLP 494 Score = 68.2 bits (165), Expect = 1e-11 Identities = 44/137 (32%), Positives = 66/137 (48%), Gaps = 2/137 (1%) Query: 98 PVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFL 155 P +P +H L ++ N + L + LR + L +NR+R + R L L L Sbjct: 495 PGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLL 554 Query: 156 YMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPD 215 + NQL E+P LP +LE L L N IS +P F NL + L+ N+L+ G Sbjct: 555 DIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDS 614 Query: 216 TFHGLKNLMQLNLAHNI 232 F LK+L L++ N+ Sbjct: 615 AFRRLKHLQVLDIEGNL 631 >gi|19743846 decorin isoform a preproprotein [Homo sapiens] Length = 359 Score = 147 bits (372), Expect = 1e-35 Identities = 91/289 (31%), Positives = 150/289 (51%), Gaps = 15/289 (5%) Query: 54 EPTDLPPPLPPG---PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYL 109 E + + P +P PS+ P CP C C + C L KVP +PP L L Sbjct: 32 EASGIGPEVPDDRDFEPSLGPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDL 88 Query: 110 QNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSAL 169 QNN ITE+ F+N L + L NN+I K+ L L LY+ KNQL+E+P + Sbjct: 89 QNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM 148 Query: 170 PRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLA 229 P+ L++LR +N I+++ F+ L +++++L N L + F G+K L + +A Sbjct: 149 PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIA 208 Query: 230 HNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLT--DRGLPKNS 287 + +P +P ++ +L+LD NKI + K NLA + L++N ++ D G + Sbjct: 209 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG---SL 265 Query: 288 FNISNLLVLHLSHNRISSVP---AINNRLEHLYLNNNSIEKINGTQICP 333 N +L LHL +N+++ VP A + ++ +YL+NN+I + + CP Sbjct: 266 ANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCP 314 Score = 85.5 bits (210), Expect = 7e-17 Identities = 63/212 (29%), Positives = 103/212 (48%), Gaps = 13/212 (6%) Query: 162 LEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLK 221 L++VP LP + L L N I+ I G F L+NL L L +N++S P F L Sbjct: 72 LDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISK--VSPGAFTPLV 129 Query: 222 NLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDR 281 L +L L+ N L+++P ++P + +L N+I + F + I L N L Sbjct: 130 KLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSS 189 Query: 282 GLPKNSFN-ISNLLVLHLSHNRISSVP-AINNRLEHLYLNNNSIEKINGTQICP-NDL-- 336 G+ +F + L + ++ I+S+P + L L+L+ N I +++ + N+L Sbjct: 190 GIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAK 249 Query: 337 --VAFHDFSS----DLENVPHLRYLRLDGNYL 362 ++F+ S+ L N PHLR L LD N L Sbjct: 250 LGLSFNSISAVDNGSLANTPHLRELHLDNNKL 281 >gi|4503271 decorin isoform a preproprotein [Homo sapiens] Length = 359 Score = 147 bits (372), Expect = 1e-35 Identities = 91/289 (31%), Positives = 150/289 (51%), Gaps = 15/289 (5%) Query: 54 EPTDLPPPLPPG---PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYL 109 E + + P +P PS+ P CP C C + C L KVP +PP L L Sbjct: 32 EASGIGPEVPDDRDFEPSLGPVCPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDL 88 Query: 110 QNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSAL 169 QNN ITE+ F+N L + L NN+I K+ L L LY+ KNQL+E+P + Sbjct: 89 QNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKM 148 Query: 170 PRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLA 229 P+ L++LR +N I+++ F+ L +++++L N L + F G+K L + +A Sbjct: 149 PKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIA 208 Query: 230 HNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLT--DRGLPKNS 287 + +P +P ++ +L+LD NKI + K NLA + L++N ++ D G + Sbjct: 209 DTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNG---SL 265 Query: 288 FNISNLLVLHLSHNRISSVP---AINNRLEHLYLNNNSIEKINGTQICP 333 N +L LHL +N+++ VP A + ++ +YL+NN+I + + CP Sbjct: 266 ANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCP 314 Score = 85.5 bits (210), Expect = 7e-17 Identities = 63/212 (29%), Positives = 103/212 (48%), Gaps = 13/212 (6%) Query: 162 LEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLK 221 L++VP LP + L L N I+ I G F L+NL L L +N++S P F L Sbjct: 72 LDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISK--VSPGAFTPLV 129 Query: 222 NLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDR 281 L +L L+ N L+++P ++P + +L N+I + F + I L N L Sbjct: 130 KLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSS 189 Query: 282 GLPKNSFN-ISNLLVLHLSHNRISSVP-AINNRLEHLYLNNNSIEKINGTQICP-NDL-- 336 G+ +F + L + ++ I+S+P + L L+L+ N I +++ + N+L Sbjct: 190 GIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAK 249 Query: 337 --VAFHDFSS----DLENVPHLRYLRLDGNYL 362 ++F+ S+ L N PHLR L LD N L Sbjct: 250 LGLSFNSISAVDNGSLANTPHLRELHLDNNKL 281 >gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] Length = 510 Score = 138 bits (347), Expect = 9e-33 Identities = 101/320 (31%), Positives = 149/320 (46%), Gaps = 33/320 (10%) Query: 59 PPPLPPGPPSIFPD-----------CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHY 106 PPP+ + FP CP C CP + CD +LR P I + Sbjct: 19 PPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQH 76 Query: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEE 164 L LQNN + ELP +GLR +NL NN I + E L L L + N+L Sbjct: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSV 136 Query: 165 VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLM 224 P LPR+L L+ N + I P F + L + L +N+LS+ PD F G + + Sbjct: 137 APQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIA 196 Query: 225 QLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284 L+L++N L +PP +P ++ +L+L +N I +P G L + L +N+LTD GL Sbjct: 197 TLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLD 256 Query: 285 KNSFN-ISNLLVLHLSHNRISSVPA-INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDF 342 +F+ + +L L LSHN++++VPA + L L+L N I ++ + Sbjct: 257 ATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR------------ 304 Query: 343 SSDLENVPHLRYLRLDGNYL 362 L LRYL L N L Sbjct: 305 ---LHGARGLRYLLLQHNQL 321 Score = 103 bits (256), Expect = 3e-22 Identities = 84/294 (28%), Positives = 129/294 (43%), Gaps = 16/294 (5%) Query: 100 IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYM 157 +P + L N + E+ +F LR + L NN++ + + L + Sbjct: 141 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSL 200 Query: 158 EKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTF 217 NQL +P +LP +LE+L L N IS++P G S+ L L LQHN+L+D TF Sbjct: 201 SNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTF 260 Query: 218 HGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277 L +L L+L+HN L +P +P + L+L N+I + L ++ L +N+ Sbjct: 261 SKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQ 320 Query: 278 LTDRGLPKNSFN-ISNLLVLHLSHNRISSV-PAINNRLEHLYLNNNSIEKINGTQICP-- 333 L GLP + + L LHL N + V PA+ RL L L +N + + + Sbjct: 321 LGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 380 Query: 334 ---------NDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQ 378 N L + + LR L L GN L +P+ L R LQ Sbjct: 381 GLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 433 Score = 79.0 bits (193), Expect = 7e-15 Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 5/214 (2%) Query: 94 LRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLP 150 L VP +P + L+L N I ++ A GLR++ L +N++ + L L Sbjct: 276 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 335 Query: 151 GLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDG 210 GL L++ N L+ VP ALPR L L L NH++ + L L+L +NRL+ Sbjct: 336 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 395 Query: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAF 270 F L+ L L+LA N L ++P +PT + L L N++ + L Sbjct: 396 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 455 Query: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRIS 304 + L +N+L + +++ L L + H +S Sbjct: 456 LSLAHNRLRVGDIGPGTWH--ELQALQVRHRLVS 487 >gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] Length = 512 Score = 138 bits (347), Expect = 9e-33 Identities = 101/320 (31%), Positives = 149/320 (46%), Gaps = 33/320 (10%) Query: 59 PPPLPPGPPSIFPD-----------CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHY 106 PPP+ + FP CP C CP + CD +LR P I + Sbjct: 21 PPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQH 78 Query: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEE 164 L LQNN + ELP +GLR +NL NN I + E L L L + N+L Sbjct: 79 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSV 138 Query: 165 VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLM 224 P LPR+L L+ N + I P F + L + L +N+LS+ PD F G + + Sbjct: 139 APQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIA 198 Query: 225 QLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284 L+L++N L +PP +P ++ +L+L +N I +P G L + L +N+LTD GL Sbjct: 199 TLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLD 258 Query: 285 KNSFN-ISNLLVLHLSHNRISSVPA-INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDF 342 +F+ + +L L LSHN++++VPA + L L+L N I ++ + Sbjct: 259 ATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAAR------------ 306 Query: 343 SSDLENVPHLRYLRLDGNYL 362 L LRYL L N L Sbjct: 307 ---LHGARGLRYLLLQHNQL 323 Score = 103 bits (256), Expect = 3e-22 Identities = 84/294 (28%), Positives = 129/294 (43%), Gaps = 16/294 (5%) Query: 100 IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYM 157 +P + L N + E+ +F LR + L NN++ + + L + Sbjct: 143 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSL 202 Query: 158 EKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTF 217 NQL +P +LP +LE+L L N IS++P G S+ L L LQHN+L+D TF Sbjct: 203 SNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTF 262 Query: 218 HGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNK 277 L +L L+L+HN L +P +P + L+L N+I + L ++ L +N+ Sbjct: 263 SKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQ 322 Query: 278 LTDRGLPKNSFN-ISNLLVLHLSHNRISSV-PAINNRLEHLYLNNNSIEKINGTQICP-- 333 L GLP + + L LHL N + V PA+ RL L L +N + + + Sbjct: 323 LGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATP 382 Query: 334 ---------NDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQ 378 N L + + LR L L GN L +P+ L R LQ Sbjct: 383 GLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 435 Score = 79.0 bits (193), Expect = 7e-15 Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 5/214 (2%) Query: 94 LRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLP 150 L VP +P + L+L N I ++ A GLR++ L +N++ + L L Sbjct: 278 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 337 Query: 151 GLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDG 210 GL L++ N L+ VP ALPR L L L NH++ + L L+L +NRL+ Sbjct: 338 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 397 Query: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAF 270 F L+ L L+LA N L ++P +PT + L L N++ + L Sbjct: 398 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 457 Query: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRIS 304 + L +N+L + +++ L L + H +S Sbjct: 458 LSLAHNRLRVGDIGPGTWH--ELQALQVRHRLVS 489 >gi|41350214 asporin [Homo sapiens] Length = 380 Score = 137 bits (344), Expect = 2e-32 Identities = 90/293 (30%), Positives = 145/293 (49%), Gaps = 15/293 (5%) Query: 50 DEPAEPTDLPPPLPPG----PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRI 104 D+ E L P P P +FP CP C C + ++C L VP IP Sbjct: 48 DDDDEDNSLFPTREPRSHFFPFDLFPMCPFGCQC---YSRVVHCSDLGLTSVPTNIPFDT 104 Query: 105 HYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEE 164 L LQNN I E+ F+ T L + L+NN++ KI + L LY+ NQL E Sbjct: 105 RMLDLQNNKIKEIKENDFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSE 164 Query: 165 VPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLM 224 +P LP++L +LR+ +N + +I F + L +L++ N L + +P F G+ + Sbjct: 165 IPLNLPKSLAELRIHENKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVF 223 Query: 225 QLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLP 284 + +A L +P +P + +L+LD NKI T+ FK + L + L NK+TD + Sbjct: 224 HIRIAEAKLTSVPKGLPPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITD--IE 281 Query: 285 KNSF-NISNLLVLHLSHNRISSVPAINNRLEHL---YLNNNSIEKINGTQICP 333 S NI + +HL +N++ +P+ L++L +L++NSI ++ CP Sbjct: 282 NGSLANIPRVREIHLENNKLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCP 334 >gi|4502403 biglycan preproprotein [Homo sapiens] Length = 368 Score = 136 bits (343), Expect = 3e-32 Identities = 97/295 (32%), Positives = 149/295 (50%), Gaps = 13/295 (4%) Query: 46 FPQPDEPAEPTDLPPPLPPGP--PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPP 102 F DE A D L P P+ CP C+C + C L+ VP I P Sbjct: 34 FMMNDEEASGADTSGVLDPDSVTPTYSAMCPFGCHC---HLRVVQCSDLGLKSVPKEISP 90 Query: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162 L LQNN I+EL + F+ L + L NN+I KI ++ L L LY+ KN L Sbjct: 91 DTTLLDLQNNDISELRKDDFKGLQHLYALVLVNNKISKIHEKAFSPLRKLQKLYISKNHL 150 Query: 163 EEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKN 222 E+P LP +L +LR+ N I ++P GVFS L N+ +++ N L + F+P F GLK Sbjct: 151 VEIPPNLPSSLVELRIHDNRIRKVPKGVFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK- 209 Query: 223 LMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRG 282 L L ++ L +P +P +++L+LD NKI+ I + L + L +N++ R Sbjct: 210 LNYLRISEAKLTGIPKDLPETLNELHLDHNKIQAIELEDLLRYSKLYRLGLGHNQI--RM 267 Query: 283 LPKNSFN-ISNLLVLHLSHNRISSVPA---INNRLEHLYLNNNSIEKINGTQICP 333 + S + + L LHL +N+++ VP+ L+ +YL++N+I K+ CP Sbjct: 268 IENGSLSFLPTLRELHLDNNKLARVPSGLPDLKLLQVVYLHSNNITKVGVNDFCP 322 >gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] Length = 699 Score = 123 bits (309), Expect = 2e-28 Identities = 91/279 (32%), Positives = 137/279 (49%), Gaps = 11/279 (3%) Query: 55 PTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIP-PRIHYLYLQNNF 113 P+ P P PP P Y + C + L ++P + P+I L L N Sbjct: 301 PSRSPLPAPPRGTLRLPSGCSLSY------RTISCINAMLTQIPPLTAPQITSLELTGNS 354 Query: 114 ITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPSALPR 171 I +P E+F L ++L N I I + + L L+ L M+ N L ++PS LP Sbjct: 355 IASIPDEAFNGLPNLERLDLSKNNITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPS 414 Query: 172 NLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHN 231 LE+L++++N++ I S L L+ L+L+ N LS+ P F LK+L L L N Sbjct: 415 TLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKN 474 Query: 232 ILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTD-RGLPKNSFNI 290 R +P +P +I +LYL++N+IE I F + I L YNK+ + R P N Sbjct: 475 KFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQ 534 Query: 291 SNLLVLHLSHNRISSVPA-INNRLEHLYLNNNSIEKING 328 NL + LS+N++ VP+ + L HL L N IE+I G Sbjct: 535 ENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPG 573 Score = 117 bits (293), Expect = 2e-26 Identities = 84/306 (27%), Positives = 150/306 (49%), Gaps = 20/306 (6%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQ 143 L D NL ++P +P + L + N + + ES + L + L+ N + + ++ Sbjct: 398 LNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNP 457 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQ 203 + L L +L + KN+ +P LP ++E+L L N I I F+ + ++ L+ Sbjct: 458 LAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLR 517 Query: 204 HNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFK 263 +N++ + P + +NL ++L++N L +P +P ++ L L N+IE IP F Sbjct: 518 YNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFG 577 Query: 264 SF-PNLAFIRLNYNKLTDRGLPKNSF--NISNLLVLHLSHNRISSVPAINNRLEHLY--- 317 P L ++ L++NKL D G+ + SF +L L L HN + S+P ++ L+ Sbjct: 578 HMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLR 637 Query: 318 LNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLK-PPIPLDLMMCFRL 376 LNNN I I +IC +++ ++ +L +L L+ NY+K IP C R Sbjct: 638 LNNNKIRNILPEEIC----------NAEEDDDSNLEHLHLENNYIKIREIPSYTFSCIRS 687 Query: 377 LQSVVI 382 S+V+ Sbjct: 688 YSSIVL 693 >gi|225579152 insulin-like growth factor binding protein, acid labile subunit isoform 1 precursor [Homo sapiens] Length = 643 Score = 110 bits (276), Expect = 2e-24 Identities = 92/302 (30%), Positives = 146/302 (48%), Gaps = 41/302 (13%) Query: 64 PGPPSIF--PDCPRECYCPPDFPS---ALYCDSRNLRKVPV-IPPRIHYLYLQNNFITEL 117 PG P P CP C C D + +++C SRNL ++P +P L+L N ++ + Sbjct: 68 PGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSV 127 Query: 118 PVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEV---PSALPRNLE 174 P +FQN + L ++NL ++ ++ + L L L L++E+NQL + A L Sbjct: 128 PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALA 187 Query: 175 QLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLS---DGVFK------------------ 213 L LS N +SR+ G+F L +L L+L N L+ D F+ Sbjct: 188 SLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYL 247 Query: 214 -PDTFHGLKNLMQLNLAHNILRKMPPRV---PTAIHQLYLDSNKIETIPNGYFKSFPNLA 269 P F GL L +L+L+ N LR + V + +LYLD N I + G F L Sbjct: 248 QPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALR 307 Query: 270 FIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSVPAINNR----LEHLYLNNNSIE 324 ++ L++N++ GL +++F + L VL LSHN I+S+ + LE L L +N I Sbjct: 308 WLDLSHNRVA--GLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 365 Query: 325 KI 326 ++ Sbjct: 366 QL 367 Score = 83.6 bits (205), Expect = 3e-16 Identities = 71/231 (30%), Positives = 116/231 (50%), Gaps = 15/231 (6%) Query: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163 + L L +N I L +F++ L + L +NRIR++ +R E L L L ++ NQL+ Sbjct: 330 LRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQ 389 Query: 164 EVPSAL---PRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGL 220 EV + N+ + LS N + +P VF L L L L+ + L G +P TF GL Sbjct: 390 EVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCL--GRIRPHTFTGL 447 Query: 221 KNLMQLNLAHNILRKMPPRVPTAIHQLY---LDSNKIETIPNGYFKSFPNLAFIRLNYNK 277 L +L L N L + + + +L L SN++ +P+ F+ L ++ L+ N+ Sbjct: 448 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 507 Query: 278 LTDRGLPKNSFN-ISNLLVLHLSHNRISSVP----AINNRLEHLYLNNNSI 323 L + LP ++ + L +SHNR+ ++P A RL +L L NNS+ Sbjct: 508 LAE--LPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSL 556 Score = 64.7 bits (156), Expect = 1e-10 Identities = 45/153 (29%), Positives = 77/153 (50%), Gaps = 6/153 (3%) Query: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162 ++H L+L+ + + + +F +GLR + L +N + I+++ L L L+ L + NQL Sbjct: 425 KLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 484 Query: 163 EEVPSALPR---NLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219 +P L + LE L LS+N ++ +P L+ LD+ HNRL Sbjct: 485 THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLE--ALPNSLLAP 542 Query: 220 LKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSN 252 L L L+L +N LR P+ P + +L+L+ N Sbjct: 543 LGRLRYLSLRNNSLRTFTPQ-PPGLERLWLEGN 574 >gi|4826772 insulin-like growth factor binding protein, acid labile subunit isoform 2 precursor [Homo sapiens] Length = 605 Score = 110 bits (276), Expect = 2e-24 Identities = 92/302 (30%), Positives = 146/302 (48%), Gaps = 41/302 (13%) Query: 64 PGPPSIF--PDCPRECYCPPDFPS---ALYCDSRNLRKVPV-IPPRIHYLYLQNNFITEL 117 PG P P CP C C D + +++C SRNL ++P +P L+L N ++ + Sbjct: 30 PGTPGEAEGPACPAACVCSYDDDADELSVFCSSRNLTRLPDGVPGGTQALWLDGNNLSSV 89 Query: 118 PVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEV---PSALPRNLE 174 P +FQN + L ++NL ++ ++ + L L L L++E+NQL + A L Sbjct: 90 PPAAFQNLSSLGFLNLQGGQLGSLEPQALLGLENLCHLHLERNQLRSLALGTFAHTPALA 149 Query: 175 QLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLS---DGVFK------------------ 213 L LS N +SR+ G+F L +L L+L N L+ D F+ Sbjct: 150 SLGLSNNRLSRLEDGLFEGLGSLWDLNLGWNSLAVLPDAAFRGLGSLRELVLAGNRLAYL 209 Query: 214 -PDTFHGLKNLMQLNLAHNILRKMPPRV---PTAIHQLYLDSNKIETIPNGYFKSFPNLA 269 P F GL L +L+L+ N LR + V + +LYLD N I + G F L Sbjct: 210 QPALFSGLAELRELDLSRNALRAIKANVFVQLPRLQKLYLDRNLIAAVAPGAFLGLKALR 269 Query: 270 FIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSVPAINNR----LEHLYLNNNSIE 324 ++ L++N++ GL +++F + L VL LSHN I+S+ + LE L L +N I Sbjct: 270 WLDLSHNRVA--GLLEDTFPGLLGLRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIR 327 Query: 325 KI 326 ++ Sbjct: 328 QL 329 Score = 83.6 bits (205), Expect = 3e-16 Identities = 71/231 (30%), Positives = 116/231 (50%), Gaps = 15/231 (6%) Query: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163 + L L +N I L +F++ L + L +NRIR++ +R E L L L ++ NQL+ Sbjct: 292 LRVLRLSHNAIASLRPRTFKDLHFLEELQLGHNRIRQLAERSFEGLGQLEVLTLDHNQLQ 351 Query: 164 EVPSAL---PRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGL 220 EV + N+ + LS N + +P VF L L L L+ + L G +P TF GL Sbjct: 352 EVKAGAFLGLTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCL--GRIRPHTFTGL 409 Query: 221 KNLMQLNLAHNILRKMPPRVPTAIHQLY---LDSNKIETIPNGYFKSFPNLAFIRLNYNK 277 L +L L N L + + + +L L SN++ +P+ F+ L ++ L+ N+ Sbjct: 410 SGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNR 469 Query: 278 LTDRGLPKNSFN-ISNLLVLHLSHNRISSVP----AINNRLEHLYLNNNSI 323 L + LP ++ + L +SHNR+ ++P A RL +L L NNS+ Sbjct: 470 LAE--LPADALGPLQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNNSL 518 Score = 64.7 bits (156), Expect = 1e-10 Identities = 45/153 (29%), Positives = 77/153 (50%), Gaps = 6/153 (3%) Query: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162 ++H L+L+ + + + +F +GLR + L +N + I+++ L L L+ L + NQL Sbjct: 387 KLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDNGLVGIEEQSLWGLAELLELDLTSNQL 446 Query: 163 EEVPSALPR---NLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHG 219 +P L + LE L LS+N ++ +P L+ LD+ HNRL Sbjct: 447 THLPHRLFQGLGKLEYLLLSRNRLAELPADALGPLQRAFWLDVSHNRLE--ALPNSLLAP 504 Query: 220 LKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSN 252 L L L+L +N LR P+ P + +L+L+ N Sbjct: 505 LGRLRYLSLRNNSLRTFTPQ-PPGLERLWLEGN 536 >gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] Length = 421 Score = 110 bits (274), Expect = 3e-24 Identities = 103/345 (29%), Positives = 145/345 (42%), Gaps = 44/345 (12%) Query: 59 PPPLPPGPPSIFPD-----------CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHY 106 PPP+ + FP CP C CP + CD +LR P I + Sbjct: 19 PPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPR--VDTVDCDGLDLRVFPDNITRAAQH 76 Query: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVP 166 L LQNN + ELP +GLR +NL NN I E LP F + QL+ + Sbjct: 77 LSLQNNQLQELPYNELSRLSGLRTLNLHNNLISS------EGLPDEAFESL--TQLQHLC 128 Query: 167 SALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQL 226 A +N N IS++P G S+ L L LQHN+L+D TF L +L L Sbjct: 129 VAHNKN--------NLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 180 Query: 227 NLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKN 286 +L+HN L +P +P + L+L N+I + L ++ L +N+L GLP Sbjct: 181 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 240 Query: 287 SFN-ISNLLVLHLSHNRISSV-PAINNRLEHLYLNNNSIEKINGTQICP----------- 333 + + L LHL N + V PA+ RL L L +N + + + Sbjct: 241 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 300 Query: 334 NDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQ 378 N L + + LR L L GN L +P+ L R LQ Sbjct: 301 NRLASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 344 Score = 79.0 bits (193), Expect = 7e-15 Identities = 60/214 (28%), Positives = 98/214 (45%), Gaps = 5/214 (2%) Query: 94 LRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQRVLEKLP 150 L VP +P + L+L N I ++ A GLR++ L +N++ + L L Sbjct: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246 Query: 151 GLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDG 210 GL L++ N L+ VP ALPR L L L NH++ + L L+L +NRL+ Sbjct: 247 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 306 Query: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAF 270 F L+ L L+LA N L ++P +PT + L L N++ + L Sbjct: 307 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366 Query: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRIS 304 + L +N+L + +++ L L + H +S Sbjct: 367 LSLAHNRLRVGDIGPGTWH--ELQALQVRHRLVS 398 >gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo sapiens] Length = 674 Score = 100 bits (250), Expect = 2e-21 Identities = 77/258 (29%), Positives = 121/258 (46%), Gaps = 30/258 (11%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWI 131 CP C C F +YC+ R L +P IP LYLQNN I Sbjct: 54 CPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQNNQINNA-------------- 96 Query: 132 NLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVF 191 + + K++ +V+ Y+ +N L+E P LPR+L +L L N++ I Sbjct: 97 GIPQDLKTKVNVQVI---------YLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSL 147 Query: 192 SKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDS 251 +++ L L L N +S + D F K L L L+ N L +P +P + +L LD Sbjct: 148 ARIPLLEKLHLDDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDD 207 Query: 252 NKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFN-ISNLLVLHLSHNRISSVP--A 308 N+I TIP FK +L + L+ N L ++ + ++F+ + NL L L N +++ P Sbjct: 208 NRISTIPLHAFKGLNSLRRLVLDGNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNL 267 Query: 309 INNRLEHLYLNNNSIEKI 326 + L+ LYL +N+I I Sbjct: 268 PSAHLQKLYLQDNAISHI 285 Score = 62.4 bits (150), Expect = 7e-10 Identities = 47/149 (31%), Positives = 73/149 (48%), Gaps = 6/149 (4%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRI--RKIDQ 143 L+ +L +P +P + L L +N I+ +P+ +F+ LR + LD N + ++I Sbjct: 182 LFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLDGNLLANQRIAD 241 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALPR-NLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202 +L L L + +N L P LP +L++L L N IS IP +K+ L LDL Sbjct: 242 DTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTLAKMRELERLDL 301 Query: 203 QHNRLSDGVFKPDTFHGLKNLMQLNLAHN 231 +N L+ F L NL QL L +N Sbjct: 302 SNNNLT--TLPRGLFDDLGNLAQLLLRNN 328 >gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo sapiens] Length = 757 Score = 99.4 bits (246), Expect = 5e-21 Identities = 84/274 (30%), Positives = 122/274 (44%), Gaps = 37/274 (13%) Query: 66 PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNA 125 P + P +C C L CD NLR VP + + + LQ N I +LP + F+N Sbjct: 93 PECLVGSVPVQCLCQG---LELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNY 149 Query: 126 TGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISR 185 L+ + L NN+I I L L LY LS N I+ Sbjct: 150 HDLQKLYLQNNKITSISIYAFRGLNSLTKLY---------------------LSHNRITF 188 Query: 186 IPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV----P 241 + PGVF L L L ++ N LS P TF+GL +L+ L L +N+L ++P + Sbjct: 189 LKPGVFEDLHRLEWLIIEDNHLSR--ISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHM 246 Query: 242 TAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLSH 300 +H L L+ N I + N F S NL + + NK+ L +N+F + L L L Sbjct: 247 PRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINH--LNENTFAPLQKLDELDLGS 304 Query: 301 NRISSVPAI----NNRLEHLYLNNNSIEKINGTQ 330 N+I ++P + L L L+ N I+KI Q Sbjct: 305 NKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQ 338 Score = 47.0 bits (110), Expect = 3e-05 Identities = 41/161 (25%), Positives = 76/161 (47%), Gaps = 20/161 (12%) Query: 222 NLMQLNLAHNILRKMPPRVPTAIH---QLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKL 278 N+ ++L N++RK+PP H +LYL +NKI +I F+ +L + L++N++ Sbjct: 127 NVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNSLTKLYLSHNRI 186 Query: 279 T--DRGLPKNSFNISNLLVLHLSHNRISSVPAIN-NRLEHLYLNNNSIEKINGTQICPND 335 T G+ ++ + L++ +RIS N L L L NN + ++ +C Sbjct: 187 TFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLC--- 243 Query: 336 LVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRL 376 +++P L +L L+GN++ L + C L Sbjct: 244 -----------QHMPRLHWLDLEGNHIHNLRNLTFISCSNL 273 Score = 28.9 bits (63), Expect = 8.1 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 12/113 (10%) Query: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162 ++ L L +N I LP F++ L +NL N I+KI + L L L +E ++ Sbjct: 296 KLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEI 355 Query: 163 EEVPSALPR---NLEQLRLSQ-------NHISRIPPGV--FSKLENLLLLDLQ 203 + + R NL + + H+ P S LENLL +Q Sbjct: 356 SNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQ 408 >gi|20302168 toll-like receptor 8 [Homo sapiens] Length = 1041 Score = 99.0 bits (245), Expect = 6e-21 Identities = 87/299 (29%), Positives = 136/299 (45%), Gaps = 49/299 (16%) Query: 89 CDSRNLRKVP-VIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNN----------- 136 C +R L++VP + + L L +NFIT + ESFQ L INL++N Sbjct: 49 CSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPG 108 Query: 137 ---RIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSK 193 I L L L +E NQL ++PS LP +L +L L QN+I I S+ Sbjct: 109 IQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISR 168 Query: 194 LENLLLLDLQHN----------RLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTA 243 L NL L L N + DGVF+ L NL L+L+ N L +PP++P++ Sbjct: 169 LINLKNLYLAWNCYFNKVCEKTNIEDGVFET-----LTNLELLSLSFNSLSHVPPKLPSS 223 Query: 244 IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRI 303 + +L+L + +I+ I FK NL + L+ N P +++ Sbjct: 224 LRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAF 283 Query: 304 SSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL 362 ++ +L +L L++ S+ KIN ++ +N+PHL+ L L+ NYL Sbjct: 284 QNL----TQLRYLNLSSTSLRKIN---------------AAWFKNMPHLKVLDLEFNYL 323 Score = 64.3 bits (155), Expect = 2e-10 Identities = 65/225 (28%), Positives = 111/225 (49%), Gaps = 29/225 (12%) Query: 128 LRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ-----------LEEVPSALPRNLEQL 176 +++++L NNR+ + L +L L L + N LE + + NL+ L Sbjct: 532 VKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFT--NLKVL 589 Query: 177 RLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDT------FHGLKNLMQLNLAH 230 LS N+I + + ++L+ L NRL D ++ D F GLKNL +L+L+ Sbjct: 590 NLSHNNIYTLTDKYNLESKSLVELVFSGNRL-DILWNDDDNRYISIFKGLKNLTRLDLSL 648 Query: 231 NILRKMPPR----VPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKN 286 N L+ +P +P ++ +L+++ N ++ + FP L + L NKL + Sbjct: 649 NRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLS 708 Query: 287 SFNISNLLVLHLSHNRISSVP----AINNRLEHLYLNNNSIEKIN 327 F S+L L LSHNRIS +P + + L+HL L++N ++ IN Sbjct: 709 DFT-SSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTIN 752 Score = 51.6 bits (122), Expect = 1e-06 Identities = 78/281 (27%), Positives = 124/281 (44%), Gaps = 59/281 (20%) Query: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE-EVPSA-----LPRNLE 174 +FQN T LR++NL + +RKI+ + +P L L +E N L E+ S LPR LE Sbjct: 282 AFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPR-LE 340 Query: 175 QLRLSQNHISRIPPGV------FSKLENLLLLDLQ---HNRLSDGVFKPDTFHGLKNLMQ 225 L LS N+I P FSKL +L L L+ L + F+P L NL Sbjct: 341 ILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQP--LMQLPNLST 398 Query: 226 LNLAHNILRKMPPRVPTAIHQL---YLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRG 282 +NL N ++++ ++ L YL N+I + +S+ N + + + K Sbjct: 399 INLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTD 458 Query: 283 LP----KNSFNISNLLV----------LHLSHNRISSVPAINNRLEHL----YLN---NN 321 N ++ + L+ L LS N I + N+ E+L LN N+ Sbjct: 459 FEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGP--NQFENLPDIACLNLSANS 516 Query: 322 SIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL 362 + + ++GT+ FS+ +PH++YL L N L Sbjct: 517 NAQVLSGTE-----------FSA----IPHVKYLDLTNNRL 542 Score = 44.7 bits (104), Expect = 1e-04 Identities = 32/105 (30%), Positives = 55/105 (52%), Gaps = 4/105 (3%) Query: 107 LYLQNNFITELPVESFQNA-TGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEV 165 L L N + +P E+F N L +++++N ++ + +L++ P L L + N+L + Sbjct: 644 LDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFL 703 Query: 166 PSALP---RNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRL 207 +L +L L LS N IS +P G S++ +L LDL N L Sbjct: 704 TDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLL 748 Score = 36.6 bits (83), Expect = 0.039 Identities = 75/358 (20%), Positives = 130/358 (36%), Gaps = 98/358 (27%) Query: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKI-------------DQRVLEK 148 P + + L NFI ++ + FQN + L I L NRI + QR + K Sbjct: 394 PNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRK 453 Query: 149 LPGLVF----------------------------------LYMEKNQLEEVPSALPRNL- 173 F ++ NQ E +P NL Sbjct: 454 RRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLS 513 Query: 174 -------------------EQLRLSQNHISRIPPGVFSKLENLLLLDLQHN----RLSDG 210 + L L+ N + ++L +L +LDL +N R++ Sbjct: 514 ANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGV 573 Query: 211 VFKPDTFHGLKNLMQLNLAHNILRKMPPRV---PTAIHQLYLDSNKIETIPN-------G 260 + NL LNL+HN + + + ++ +L N+++ + N Sbjct: 574 THHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYIS 633 Query: 261 YFKSFPNLAFIRLNYNKLTDRGLPKNSF-NI-SNLLVLHLSHNRIS----SVPAINNRLE 314 FK NL + L+ N+L + +P +F N+ ++L LH++ N + ++ RLE Sbjct: 634 IFKGLKNLTRLDLSLNRL--KHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLE 691 Query: 315 HLYLNNNSI----EKINGTQICPNDLVAFHDF-----SSDLENVPHLRYLRLDGNYLK 363 L L N + + ++ L+ H+ S L V L++L L N LK Sbjct: 692 LLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLK 749 >gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sapiens] Length = 516 Score = 99.0 bits (245), Expect = 6e-21 Identities = 88/304 (28%), Positives = 138/304 (45%), Gaps = 50/304 (16%) Query: 67 PSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHY-LYLQNNFITELPVESFQNA 125 P++ CP +C C YCDS+ VP + L L++N ITEL + F + Sbjct: 28 PALGMACPPKCRCEK---LLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASF 84 Query: 126 TGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISR 185 + L W++LD+N+I + + + L L++L LS N I Sbjct: 85 SQLTWLHLDHNQISTVKEDAFQGL---------------------YKLKELILSSNKIFY 123 Query: 186 IPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV---PT 242 +P F++L NL LDL N+LS P+ F+GL+ L L+L N LR +P R+ Sbjct: 124 LPNTTFTQLINLQNLDLSFNQLSS--LHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCR 181 Query: 243 AIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNR 302 ++ L L +N++ ++ F L + L +N+LT + +S+L L L N+ Sbjct: 182 SLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINF-AHFLRLSSLHTLFLQWNK 240 Query: 303 ISSVPA----INNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLD 358 IS++ LE L L N I+ I DL F E +P+L+ L +D Sbjct: 241 ISNLTCGMEWTWGTLEKLDLTGNEIKAI--------DLTVF-------ETMPNLKILLMD 285 Query: 359 GNYL 362 N L Sbjct: 286 NNKL 289 Score = 39.7 bits (91), Expect = 0.005 Identities = 24/73 (32%), Positives = 36/73 (49%) Query: 104 IHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLE 163 +H L+LQ N I+ L L ++L N I+ ID V E +P L L M+ N+L Sbjct: 231 LHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLN 290 Query: 164 EVPSALPRNLEQL 176 + S + +L L Sbjct: 291 SLDSKILNSLRSL 303 >gi|38202222 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 99.0 bits (245), Expect = 6e-21 Identities = 78/258 (30%), Positives = 117/258 (45%), Gaps = 30/258 (11%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWI 131 CP C C F +YC+ R L +P IP LYLQNN I + S Sbjct: 31 CPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPS---------- 77 Query: 132 NLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVF 191 D + K+++ +Y+ N L+E P+ LP+ +++L L +N+I I Sbjct: 78 --DLKNLLKVER-----------IYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSL 124 Query: 192 SKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDS 251 SK+ L L L N +S + F L L L+ N L +P +P I +L LD Sbjct: 125 SKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDD 184 Query: 252 NKIETIPNGYFKSFPNLAFIRLNYNKLTDRGL-PKNSFNISNLLVLHLSHNRISSVPA-- 308 N+I TI + + +L + L+ N L + GL K FN+ NL L L N +++ P Sbjct: 185 NRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNL 244 Query: 309 INNRLEHLYLNNNSIEKI 326 L LYL +N I ++ Sbjct: 245 PGTNLRKLYLQDNHINRV 262 Score = 71.2 bits (173), Expect = 1e-12 Identities = 51/149 (34%), Positives = 73/149 (48%), Gaps = 6/149 (4%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQ 143 L+ +L +P +P I L L +N I+ + S Q T L+ + LD N + + Sbjct: 159 LFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 218 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALP-RNLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202 +V L L L + +N L P LP NL +L L NHI+R+PP FS L L LD+ Sbjct: 219 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 278 Query: 203 QHNRLSDGVFKPDTFHGLKNLMQLNLAHN 231 +N LS+ F L N+ QL L +N Sbjct: 279 SNNNLSN--LPQGIFDDLDNITQLILRNN 305 >gi|7019383 fibronectin leucine rich transmembrane protein 3 precursor [Homo sapiens] Length = 649 Score = 99.0 bits (245), Expect = 6e-21 Identities = 78/258 (30%), Positives = 117/258 (45%), Gaps = 30/258 (11%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWI 131 CP C C F +YC+ R L +P IP LYLQNN I + S Sbjct: 31 CPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNNQINNAGIPS---------- 77 Query: 132 NLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVF 191 D + K+++ +Y+ N L+E P+ LP+ +++L L +N+I I Sbjct: 78 --DLKNLLKVER-----------IYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSL 124 Query: 192 SKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDS 251 SK+ L L L N +S + F L L L+ N L +P +P I +L LD Sbjct: 125 SKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDD 184 Query: 252 NKIETIPNGYFKSFPNLAFIRLNYNKLTDRGL-PKNSFNISNLLVLHLSHNRISSVPA-- 308 N+I TI + + +L + L+ N L + GL K FN+ NL L L N +++ P Sbjct: 185 NRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNL 244 Query: 309 INNRLEHLYLNNNSIEKI 326 L LYL +N I ++ Sbjct: 245 PGTNLRKLYLQDNHINRV 262 Score = 71.2 bits (173), Expect = 1e-12 Identities = 51/149 (34%), Positives = 73/149 (48%), Gaps = 6/149 (4%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRK--IDQ 143 L+ +L +P +P I L L +N I+ + S Q T L+ + LD N + + Sbjct: 159 LFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGD 218 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALP-RNLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202 +V L L L + +N L P LP NL +L L NHI+R+PP FS L L LD+ Sbjct: 219 KVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAFSYLRQLYRLDM 278 Query: 203 QHNRLSDGVFKPDTFHGLKNLMQLNLAHN 231 +N LS+ F L N+ QL L +N Sbjct: 279 SNNNLSN--LPQGIFDDLDNITQLILRNN 305 >gi|122937309 leucine rich repeat containing 4B [Homo sapiens] Length = 713 Score = 98.2 bits (243), Expect = 1e-20 Identities = 82/266 (30%), Positives = 132/266 (49%), Gaps = 16/266 (6%) Query: 66 PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQN 124 PP+ CP C C S + C R+L +VP IP YL LQ N I + ++F++ Sbjct: 52 PPAT--SCPVACSCSNQ-ASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKH 108 Query: 125 ATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLR---LSQN 181 L + L N +RKI+ LP L L + N+L VP+ L +LR L N Sbjct: 109 LRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNN 168 Query: 182 HISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVP 241 I IP F+++ +L LDL + + + + F GL NL LNL L+ +P Sbjct: 169 PIESIPSYAFNRVPSLRRLDLGELKRLEYISEA-AFEGLVNLRYLNLGMCNLKDIPNLTA 227 Query: 242 -TAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLS 299 + +L L N+++ I G F+ +L + L + ++ + +N+F ++ +L L+LS Sbjct: 228 LVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVAT--IERNAFDDLKSLEELNLS 285 Query: 300 HNRISSVP----AINNRLEHLYLNNN 321 HN + S+P +RLE ++LN+N Sbjct: 286 HNNLMSLPHDLFTPLHRLERVHLNHN 311 >gi|153251229 chondroadherin precursor [Homo sapiens] Length = 359 Score = 95.9 bits (237), Expect = 5e-20 Identities = 70/283 (24%), Positives = 129/283 (45%), Gaps = 39/283 (13%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWIN 132 CP+ C+C D + CD L+K+P + + L LQ N L SF+ L ++ Sbjct: 23 CPQNCHCHSDLQHVI-CDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLH 81 Query: 133 LDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLR---LSQNHISRIPPG 189 L + +IR++ L L++LY+ N + + + +L +L L N ++ +P G Sbjct: 82 LQHCQIREVAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELPRG 141 Query: 190 VFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQL-- 247 + S L NL +L L +N++ + + F G K+L L L+ N L + P + L Sbjct: 142 LLSPLVNLFILQLNNNKIRE--LRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENLAK 199 Query: 248 -YLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF------------------ 288 ++D N++ + P+ + ++L++N L + +P N+F Sbjct: 200 FHVDRNQLSSYPSAALSKLRVVEELKLSHNPL--KSIPDNAFQSFGRYLETLWLDNTNLE 257 Query: 289 --------NISNLLVLHLSHNRISSVPA--INNRLEHLYLNNN 321 ++ L +HL +NR++ +P+ + LE L L NN Sbjct: 258 KFSDGAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALTNN 300 >gi|76880480 hypothetical protein LOC9865 [Homo sapiens] Length = 811 Score = 94.7 bits (234), Expect = 1e-19 Identities = 98/332 (29%), Positives = 141/332 (42%), Gaps = 49/332 (14%) Query: 66 PPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVI-----PPRIHYLYLQNNFITELPVE 120 PP P CP C C P L C +R LR VP P + L NFIT + Sbjct: 20 PPLAEPVCPERCDC--QHPQHLLCTNRGLRVVPKTSSLPSPHDVLTYSLGGNFITNITAF 77 Query: 121 SFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRL-- 178 F LR ++L N+IR + + EKL L LY+ N L+ + L +LR+ Sbjct: 78 DFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNNLLQALAPGTLAPLRKLRILY 137 Query: 179 -SQNHISRIPPGVFSKLENLLLLDLQHNRLS---DGVFKP-------------------D 215 + N ISR+ G F LE+L+ L L N L D VF P + Sbjct: 138 ANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAPLGNLLYLHLESNRIRFLGKN 197 Query: 216 TFHGLKNLMQLNLAHNILRKMPPRVPT-----AIHQLYLDSNKIETIPNGYFKSFPNLAF 270 F L L LNL+ N L+ T ++ L L +N ++ + F+ P L Sbjct: 198 AFAQLGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANNLQHLGPRIFQHLPRLGL 257 Query: 271 IRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQ 330 + L N+LT P+ + + L L L NR+S +P LE L+ S+E ++ Sbjct: 258 LSLRGNQLTHLA-PEAFWGLEALRELRLEGNRLSQLPTA--LLEPLH----SLEALD--- 307 Query: 331 ICPNDLVAFHDFSSDLENVPHLRYLRLDGNYL 362 + N+L A H + ++ LR L L N L Sbjct: 308 LSGNELSALH--PATFGHLGRLRELSLRNNAL 337 Score = 48.1 bits (113), Expect = 1e-05 Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 3/107 (2%) Query: 102 PRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQ 161 PR+ L L+ N +T L E+F LR + L+ NR+ ++ +LE L L L + N+ Sbjct: 253 PRLGLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNE 312 Query: 162 LEEVPSALPRNLEQLR---LSQNHISRIPPGVFSKLENLLLLDLQHN 205 L + A +L +LR L N +S + +F+ L LDL N Sbjct: 313 LSALHPATFGHLGRLRELSLRNNALSALSGDIFAASPALYRLDLDGN 359 >gi|109809759 leucine rich repeat transmembrane neuronal 3 [Homo sapiens] Length = 581 Score = 92.4 bits (228), Expect = 6e-19 Identities = 88/308 (28%), Positives = 132/308 (42%), Gaps = 69/308 (22%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWI 131 CP+ C C +YC+S+ L+++P I L L+ N + +L F+ L W+ Sbjct: 34 CPKGCRCEGKM---VYCESQKLQEIPSSISAGCLGLSLRYNSLQKLKYNQFKGLNQLTWL 90 Query: 132 NLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVF 191 LD+N I ID+ + R L++L LS N IS F Sbjct: 91 YLDHNHISNIDENAFNGI---------------------RRLKELILSSNRISYFLNNTF 129 Query: 192 SKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDS 251 + NL LDL +N+L + F GL+ L+ L+L N LR +P R+ Sbjct: 130 RPVTNLRNLDLSYNQLHS--LGSEQFRGLRKLLSLHLRSNSLRTIPVRI----------- 176 Query: 252 NKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSV---- 306 F+ NL + L YN++ R L +N F + L LHL HN+ S + Sbjct: 177 ----------FQDCRNLELLDLGYNRI--RSLARNVFAGMIRLKELHLEHNQFSKLNLAL 224 Query: 307 -PAINNRLEHLYLNNNSIEKINGT-----------QICPNDLVAFHDFSSDLENVPHLRY 354 P + + L++LYL N I I T + N++ AF S + VP+L+ Sbjct: 225 FPRLVS-LQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEIEAFSG-PSVFQCVPNLQR 282 Query: 355 LRLDGNYL 362 L LD N L Sbjct: 283 LNLDSNKL 290 Score = 57.4 bits (137), Expect = 2e-08 Identities = 50/148 (33%), Positives = 73/148 (49%), Gaps = 12/148 (8%) Query: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVP 166 L+L++N + +PV FQ+ L ++L NRIR + + V + L L++E NQ ++ Sbjct: 162 LHLRSNSLRTIPVRIFQDCRNLELLDLGYNRIRSLARNVFAGMIRLKELHLEHNQFSKLN 221 Query: 167 SAL-PR--NLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNL 223 AL PR +L+ L L N IS I + +L LDL N + + P F + NL Sbjct: 222 LALFPRLVSLQNLYLQWNKISVIGQTMSWTWSSLQRLDLSGNEI-EAFSGPSVFQCVPNL 280 Query: 224 MQLNLAHNILRKMPPRVPTAIHQLYLDS 251 +LNL N L T I Q LDS Sbjct: 281 QRLNLDSNKL--------TFIGQEILDS 300 >gi|4504379 leucine-rich repeat-containing G protein-coupled receptor 5 [Homo sapiens] Length = 907 Score = 92.0 bits (227), Expect = 8e-19 Identities = 89/297 (29%), Positives = 133/297 (44%), Gaps = 26/297 (8%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPVIPPRIH----YLYLQNNFITELPVESFQNATGL 128 CP C+C PD L D +L + +P + YL L N I++L + L Sbjct: 34 CPTHCHCEPDGRMLLRVDCSDLG-LSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFL 92 Query: 129 RWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPS-ALP--RNLEQLRLSQNHISR 185 + L N + I + L L L ++ NQL VP+ AL R+L+ LRL NHIS Sbjct: 93 EELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHISY 152 Query: 186 IPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRV---PT 242 +PP FS L +L L L N L++ F L L + LA N + +P + Sbjct: 153 VPPSCFSGLHSLRHLWLDDNALTE--IPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLS 210 Query: 243 AIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNR 302 ++ L+L +N+I ++ F +L + LNYN L + P +SNL L N Sbjct: 211 SLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRTLSNLKELGFHSNN 268 Query: 303 ISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDG 359 I S+P E ++ N S+ I+ P V S +++P LR L L+G Sbjct: 269 IRSIP------EKAFVGNPSLITIHFYD-NPIQFVG----RSAFQHLPELRTLTLNG 314 Score = 80.5 bits (197), Expect = 2e-15 Identities = 75/257 (29%), Positives = 116/257 (45%), Gaps = 33/257 (12%) Query: 107 LYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVP 166 L LQNN + +P E+ QN L+ + LD N I + L L L+++ N L E+P Sbjct: 119 LMLQNNQLRHVPTEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTEIP 178 Query: 167 SALPRNLEQLR---LSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNL 223 R+L L+ L+ N I IP F L +L++L L +NR+ F GL +L Sbjct: 179 VQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHS--LGKKCFDGLHSL 236 Query: 224 MQLNLAHNILRKMPPRVPTA--IHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDR 281 L+L +N L + P + T + +L SN I +IP F P+L I N + Sbjct: 237 ETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNPIQFV 296 Query: 282 G------LPK----------------NSFNISNLLVLHLSHNRISSVP-AINNRLEHLY- 317 G LP+ + +NL L L+ +ISS+P + N+L +L Sbjct: 297 GRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSLPQTVCNQLPNLQV 356 Query: 318 --LNNNSIEKINGTQIC 332 L+ N +E + +C Sbjct: 357 LDLSYNLLEDLPSFSVC 373 Score = 66.6 bits (161), Expect = 3e-11 Identities = 76/297 (25%), Positives = 127/297 (42%), Gaps = 45/297 (15%) Query: 104 IHYLYLQNNFITELPVESFQ------------------------NATGLRWINLDNNRIR 139 + +L+L +N +TE+PV++F+ N + L ++L NNRI Sbjct: 164 LRHLWLDDNALTEIPVQAFRSLSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIH 223 Query: 140 KIDQRVLEKLPGLVFLYMEKNQLEEVPSALP--RNLEQLRLSQNHISRIPPGVFSKLENL 197 + ++ + L L L + N L+E P+A+ NL++L N+I IP F +L Sbjct: 224 SLGKKCFDGLHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSL 283 Query: 198 LLLDLQHNRLSDGVFKPDTFHGLKNLMQLNL-AHNILRKMPPRVPTA-IHQLYLDSNKIE 255 + + N + F L L L L + + + P TA + L L +I Sbjct: 284 ITIHFYDNPIQ--FVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQIS 341 Query: 256 TIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNI-SNLLVLHLSHNRISSVPA------ 308 ++P PNL + L+YN L D LP SF++ L + L HN I + Sbjct: 342 SLPQTVCNQLPNLQVLDLSYNLLED--LP--SFSVCQKLQKIDLRHNEIYEIKVDTFQQL 397 Query: 309 INNRLEHLYLNNNSIEKINGTQICPN----DLVAFHDFSSDLENVPHLRYLRLDGNY 361 ++ R +L N +I N P+ DL + S + + L +L+L GN+ Sbjct: 398 LSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNH 454 Score = 44.7 bits (104), Expect = 1e-04 Identities = 26/80 (32%), Positives = 40/80 (50%) Query: 103 RIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQL 162 ++ + L++N I E+ V++FQ LR +NL N+I I LP L+ L + N L Sbjct: 375 KLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLL 434 Query: 163 EEVPSALPRNLEQLRLSQNH 182 P L L+L+ NH Sbjct: 435 SSFPITGLHGLTHLKLTGNH 454 >gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo sapiens] Length = 660 Score = 91.7 bits (226), Expect = 1e-18 Identities = 73/260 (28%), Positives = 118/260 (45%), Gaps = 34/260 (13%) Query: 73 CPRECYCPPDFPSALYCDSRNLRKVPV-IPPRIHYLYLQNNFITE--LPVESFQNATGLR 129 CP C C +F +YC+ R+L VP+ IP + LYL NN I P E Sbjct: 36 CPSVCRCDRNF---VYCNERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAE--------- 83 Query: 130 WINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPG 189 L + + +Y+ NQL+E P LP+N+ L L +N+I I Sbjct: 84 ----------------LHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRA 127 Query: 190 VFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYL 249 ++L L L L N +S + F +L L L+ N L +P +P + +L + Sbjct: 128 ALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRV 187 Query: 250 DSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSF-NISNLLVLHLSHNRISSVP- 307 D N+I I + F++ +L + ++ N LT++G+ + +F +++ L + N +S P Sbjct: 188 DENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP 247 Query: 308 -AINNRLEHLYLNNNSIEKI 326 L LYL +N I I Sbjct: 248 DLPGTHLIRLYLQDNQINHI 267 Score = 55.8 bits (133), Expect = 6e-08 Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 6/149 (4%) Query: 87 LYCDSRNLRKVPV-IPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRI--RKIDQ 143 L+ +L VPV +P + L + N I + +FQN T L + +D N + + I + Sbjct: 164 LFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAE 223 Query: 144 RVLEKLPGLVFLYMEKNQLEEVPSALP-RNLEQLRLSQNHISRIPPGVFSKLENLLLLDL 202 L L + +N L P LP +L +L L N I+ IP FS L L LD+ Sbjct: 224 GTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDI 283 Query: 203 QHNRLSDGVFKPDTFHGLKNLMQLNLAHN 231 +N+L + F L NL QL +N Sbjct: 284 SNNQLR--MLTQGVFDNLSNLKQLTARNN 310 >gi|7657419 opticin precursor [Homo sapiens] Length = 332 Score = 90.5 bits (223), Expect = 2e-18 Identities = 73/254 (28%), Positives = 108/254 (42%), Gaps = 40/254 (15%) Query: 9 LPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPS 68 LP + + S+A + T PG P PT + PT L P Sbjct: 75 LPEVKVTSLAPATSISPAKSTTAPGT---PSSNPTMT--------RPTTAGLLLSSQPNH 123 Query: 69 IFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGL 128 P C C C S++YCD +L +P +P R YLY + N I+ + E F+ T L Sbjct: 124 GLPTC-LVCVC---LGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKL 179 Query: 129 RWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPP 188 + I+L NN I ID L L L + +NQLE +P LP +E Sbjct: 180 KRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALP-VLPSGIE-------------- 224 Query: 189 GVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLY 248 LD++ NRL +P F ++ L L L+ N+L +P +P ++ ++ Sbjct: 225 ----------FLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVH 274 Query: 249 LDSNKIETIPNGYF 262 L +N IET+ F Sbjct: 275 LQNNLIETMQRDVF 288 Score = 29.3 bits (64), Expect = 6.2 Identities = 35/142 (24%), Positives = 62/142 (43%), Gaps = 20/142 (14%) Query: 233 LRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISN 292 L +PP +P LY N+I I FK L I L+ N ++ + ++F + + Sbjct: 145 LEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLIS--SIDNDAFRLLH 201 Query: 293 LLV-LHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPH 351 L L L N++ ++P + + +E L + N ++ +G Q + + Sbjct: 202 ALQDLILPENQLEALPVLPSGIEFLDVRLNRLQS-SGIQ------------PAAFRAMEK 248 Query: 352 LRYLRLDGNYLKP---PIPLDL 370 L++L L N L P+PL L Sbjct: 249 LQFLYLSDNLLDSIPGPLPLSL 270 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.142 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,046,648 Number of Sequences: 37866 Number of extensions: 1262972 Number of successful extensions: 22756 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 592 Number of HSP's successfully gapped in prelim test: 736 Number of HSP's that attempted gapping in prelim test: 10283 Number of HSP's gapped (non-prelim): 7446 length of query: 382 length of database: 18,247,518 effective HSP length: 104 effective length of query: 278 effective length of database: 14,309,454 effective search space: 3978028212 effective search space used: 3978028212 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.