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Search of human proteins with 41152506
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41152506 prostaglandin F2 receptor negative regulator [Homo
sapiens]
(879 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s... 1781 0.0
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo... 251 2e-66
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo... 245 1e-64
gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens] 228 2e-59
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens] 227 3e-59
gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m... 93 9e-19
gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m... 87 9e-17
gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens] 87 9e-17
gi|118572606 hemicentin 1 [Homo sapiens] 51 5e-06
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur... 50 1e-05
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu... 50 1e-05
gi|139948432 adlican [Homo sapiens] 48 3e-05
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur... 46 1e-04
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 46 2e-04
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur... 45 4e-04
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur... 45 4e-04
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 42 0.002
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 42 0.002
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 42 0.002
gi|222144244 fibroblast growth factor receptor 2 isoform 9 precu... 42 0.003
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu... 42 0.003
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu... 42 0.003
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 40 0.012
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 39 0.016
gi|148743776 V-set and transmembrane domain containing 2 [Homo s... 39 0.016
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 39 0.021
gi|156564390 carcinoembryonic antigen-related cell adhesion mole... 38 0.036
gi|156564378 carcinoembryonic antigen-related cell adhesion mole... 38 0.036
gi|156564393 carcinoembryonic antigen-related cell adhesion mole... 38 0.036
gi|156564388 carcinoembryonic antigen-related cell adhesion mole... 38 0.036
>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
sapiens]
Length = 879
Score = 1781 bits (4612), Expect = 0.0
Identities = 879/879 (100%), Positives = 879/879 (100%)
Query: 1 MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF 60
MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF
Sbjct: 1 MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF 60
Query: 61 SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS
Sbjct: 61 SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
Query: 121 TPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTH 180
TPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTH
Sbjct: 121 TPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTH 180
Query: 181 LALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSA 240
LALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSA
Sbjct: 181 LALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSA 240
Query: 241 DQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCN 300
DQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCN
Sbjct: 241 DQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCN 300
Query: 301 ITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLV 360
ITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLV
Sbjct: 301 ITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLV 360
Query: 361 RDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGF 420
RDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGF
Sbjct: 361 RDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGF 420
Query: 421 ADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSK 480
ADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSK
Sbjct: 421 ADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSK 480
Query: 481 QRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVN 540
QRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVN
Sbjct: 481 QRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVN 540
Query: 541 IFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPN 600
IFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPN
Sbjct: 541 IFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPN 600
Query: 601 ETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAW 660
ETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAW
Sbjct: 601 ETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAW 660
Query: 661 SPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAAL 720
SPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAAL
Sbjct: 661 SPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAAL 720
Query: 721 DPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQV 780
DPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQV
Sbjct: 721 DPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQV 780
Query: 781 HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLS 840
HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLS
Sbjct: 781 HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLS 840
Query: 841 TVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD 879
TVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD
Sbjct: 841 TVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD 879
>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
sapiens]
Length = 1194
Score = 251 bits (642), Expect = 2e-66
Identities = 219/840 (26%), Positives = 365/840 (43%), Gaps = 59/840 (7%)
Query: 8 PLLLALLSLALCRG-RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLG 64
P+L L L + R V V L R G+ + I CNVS Y GPSEQNF WS S
Sbjct: 6 PVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65
Query: 65 SSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPST 124
V++ ST + FP +Y +R++ G+I + R ++ LHI ++Q D G Y+C TPST
Sbjct: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPST 125
Query: 125 DATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALL 184
D G+Y + + V+ DSL + P +L E +P EL C AS + H+HL++
Sbjct: 126 DKQYFGSYSAKMNLVVIPDSLQ---TTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVA 182
Query: 185 WEVHR-GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQG 243
W + G V++L+ + H Y QR G+VRLD +G +RL++ +DQG
Sbjct: 183 WLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQG 242
Query: 244 SYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLT 298
+ C +EWI + G+W + K E A V +QP+ +R K + G+ ++
Sbjct: 243 EFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTV-GEPVEFR 301
Query: 299 CNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHL 358
C + D V+W+F+ +T+ + V + + + ++ + L
Sbjct: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
Query: 359 LVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWL----EPDYQVYLNA 414
+ + +E+SG Y C V+ + + + P + + L +V NA
Sbjct: 362 KIYHLRQEDSGKYNCRVT--EREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNA 419
Query: 415 SKVPGFADDPTELACRVVDTKSGEANVRFTVSWYY--RMNRRSDNVVTSELLAVMDGDWT 472
S + + +C V +G RF+V W R NRRS+ + +D D T
Sbjct: 420 SVI--LEGEDLRFSCSV--RTAGRPQGRFSVIWQLVDRQNRRSN-------IMWLDRDGT 468
Query: 473 LKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSW-VKS 531
++ G +R+ G + ++F+ I + +ED G Y C V+ W + + W +
Sbjct: 469 VQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVG 528
Query: 532 KDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAE- 590
+ S P++I ALE V A P ++F++ C I P Y +
Sbjct: 529 ERRASTPISI-TALEMG-FAVTAISRTPGVTYSDSFDLQC------IIKPHYPAWVPVSV 580
Query: 591 ----KPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQ 646
+PVG + E +++ +D V+ + + + R + + + R + +
Sbjct: 581 TWRFQPVGTV----EFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRAS 636
Query: 647 VSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDL 706
++AG Y+C+ W + W A SN +EI S T +++
Sbjct: 637 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 696
Query: 707 IKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGI---VTTSRRDWK 763
I+L C + + + + F V W+ VH ++L + +
Sbjct: 697 IQLNCSVKSQTS----QNSHFAVLWY-VHKPSDADGKLILKTTHNSAFEYGTYAEEEGLR 751
Query: 764 SDLSLER-VSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVK 822
+ L ER VS F L V +E D G+YYC V W+ SP +W K AE S +TVK
Sbjct: 752 ARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVK 811
Score = 184 bits (467), Expect = 3e-46
Identities = 182/848 (21%), Positives = 317/848 (37%), Gaps = 72/848 (8%)
Query: 24 VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82
VR+ T + VG + C + + P W+F+S S + V
Sbjct: 283 VRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 339
Query: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYED-------T 135
+ R RG++ + + ++ L I +++ D G Y C + TV G + D
Sbjct: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399
Query: 136 VQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARR 194
+ + VL + S+ L EGE C+ +A +++W+ V R R
Sbjct: 400 IPIIVLPLKSSISVEVASNASVIL-EGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRS 458
Query: 195 SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI- 253
+++ L +G PG Y +R G V+++ V +++ L + + D+G Y C V+EW+
Sbjct: 459 NIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR 518
Query: 254 AEQGNWQEIQEK--AVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRP 311
A G WQ + E+ + ++ ++ A+ + V DL C I V
Sbjct: 519 AVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 578
Query: 312 EVTWSFSRMPDSTLPGSRVLARL------DRDSLVHSSPHVALSHVDARSYHLLVRDVSK 365
VTW F + R DR S + + + + + L + S
Sbjct: 579 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAE-SSNNVRLSISRASD 637
Query: 366 ENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASK--VPGFADD 423
+G Y C LW +N +W ++AE S+ + V L+P ++ ++ SK + +
Sbjct: 638 TEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRV--LQPVTKLQVSKSKRTLTLVENK 695
Query: 424 PTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRA 483
P +L C V S N F V WY +D +L+ + +YG +++
Sbjct: 696 PIQLNCSVKSQTS--QNSHFAVLWYVHKPSDADG----KLILKTTHNSAFEYGTYAEEEG 749
Query: 484 QDGDFIFSKEHTD-TFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIF 542
F + + F+ +QR D G+YYC V W N +W K + S +
Sbjct: 750 LRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVT 809
Query: 543 WALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNET 602
DS L + Q ++ C V ++ + + V KP + E
Sbjct: 810 VKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKP-----NHPER 864
Query: 603 KYIISLDQDSVVKLENWTDASRVDGVV-LEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWS 661
+ + L +D+ + + G + LE +R + V D+G Y C V W
Sbjct: 865 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 924
Query: 662 PVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALD 721
P +W + A + + +V +L C I +
Sbjct: 925 PSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSS--- 981
Query: 722 PDDMAFDVSWFAVH--------SFGLDKAP--------------------VLLSSLDRKG 753
D F V+W+++ S GL++ L S+
Sbjct: 982 -QDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDA 1040
Query: 754 IVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIH 813
+ W+ L +R+S + + L V + QD GNY C V W+ SP W + E
Sbjct: 1041 VFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE 1100
Query: 814 SKPVFITV 821
S P+ I V
Sbjct: 1101 SAPIGIRV 1108
Score = 159 bits (401), Expect = 1e-38
Identities = 192/821 (23%), Positives = 316/821 (38%), Gaps = 57/821 (6%)
Query: 30 TLVRVVGTELVIPCNV-SDYDGPSEQNFDWSFSSLGSSFVELASTWE--VGFPAQLYQER 86
TL RV L + C V S+ S + W +G VE+ S + + Y +R
Sbjct: 154 TLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR 213
Query: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
GE+ L + L I ++QPSDQG + C G++ + + ++
Sbjct: 214 QSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVN 273
Query: 147 VGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALT 200
V P+ + E GEP E RC + + + A+ W A S L T
Sbjct: 274 VQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSW------AFNSSLIAT 327
Query: 201 HEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE-QG 257
P L E R G +++ + L + D G Y C V+E G
Sbjct: 328 MGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTG 387
Query: 258 NWQEIQEKAVEVATVVIQP--SVLRAAVPKNVSVA-EGKELDLTCNITTDRADDVRPEVT 314
+ + + K + +++ P S + V N SV EG++L +C++ T R V
Sbjct: 388 EFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVI 447
Query: 315 WSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPHVALSHVDARSYHLLVRDVSK 365
W ++ D S ++ LDRD V S V + V S+ L + + K
Sbjct: 448 W---QLVDRQNRRSNIMW-LDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRK 503
Query: 366 ENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFA-DDP 424
E+ G Y CHV+ W + W V E +S + +T LE + V S+ PG D
Sbjct: 504 EDEGQYECHVTEWVRAVDGEWQIVGERRASTP-ISITALEMGFAVTA-ISRTPGVTYSDS 561
Query: 425 TELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQ 484
+L C + A V +V+W ++ V L D +++G+RS +
Sbjct: 562 FDLQCII--KPHYPAWVPVSVTWRFQ----PVGTVEFHDLVTFTRDGGVQWGDRSSS-FR 614
Query: 485 DGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWA 544
I E ++ I R ++ + G Y CV W K NN+W + + S + I
Sbjct: 615 TRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVL 674
Query: 545 LEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNETKY 604
+ L V + ++ C V S+ ++ ++VL KP S + K
Sbjct: 675 QPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKP-----SDADGKL 729
Query: 605 IISLDQDSVVKLENWTDASRVDGVVL--EKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSP 662
I+ +S + + + + + V F + + +VSD+G Y C V W
Sbjct: 730 ILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLL 789
Query: 663 VRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALDP 722
W + A +S E+ + S SV+ ++L C++ + ++
Sbjct: 790 SPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVV-LNRTSITS 848
Query: 723 DDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIV--TTSRRDWKSDLSLERVSVLEFLLQV 780
M V WF ++ V S D ++ + K L LE S + L +
Sbjct: 849 QLM---VEWFVWKPNHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFI 905
Query: 781 HGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITV 821
QD G Y C V W+ SP+G W K AE + +TV
Sbjct: 906 QNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTV 946
Score = 135 bits (341), Expect = 1e-31
Identities = 146/656 (22%), Positives = 245/656 (37%), Gaps = 50/656 (7%)
Query: 185 WEVH--RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQ 242
W ++ P R + T + F P Y QR G + ++ V ++ L ++ + D
Sbjct: 57 WSIYLPSSPEREVQIVSTMDSSF-PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDA 115
Query: 243 GSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNIT 302
G Y C + Q + ++ VVI S+ A+P+ + E L+LTC +
Sbjct: 116 GEYECHTPST-----DKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVA 170
Query: 303 TDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVA---------LSHVDA 353
++ V W ++ + + + L RD ++HSS A L +
Sbjct: 171 SETIQHSHLSVAWLRQKVGEKPVE----VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGR 226
Query: 354 RSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLN 413
++ L + + + G +YC + W + SW+ + S A V V + ++ V L
Sbjct: 227 TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLE 286
Query: 414 ASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTL 473
K +P E C + + F VSW + S L+A M +
Sbjct: 287 TEKRLHTVGEPVEFRC--ILEAQNVPDRYFAVSWAFN----------SSLIATMGPNAVP 334
Query: 474 KYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKD 533
R G +KE F +I +ED G Y C V+ K ++ +
Sbjct: 335 VLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394
Query: 534 VFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPV 593
K + I S + V+ G +C V + R+SV+
Sbjct: 395 KRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQL---- 450
Query: 594 GDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGL 652
+ N I+ LD+D V+ ++ + S GV +E+VQ + F ++ ++ D G
Sbjct: 451 --VDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQ 508
Query: 653 YRCMVTAWSPVRGSLWREAATS-LSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFC 711
Y C VT W W+ S PI I G F + S TP V D L C
Sbjct: 509 YECHVTEWVRAVDGEWQIVGERRASTPISITALEMG--FAVTAISRTPGVTYSDSFDLQC 566
Query: 712 IITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRD-WKSDLSLER 770
II A P V+W G + L++ G+ R +++ ++E+
Sbjct: 567 IIKPHYPAWVP----VSVTW-RFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEK 621
Query: 771 V-SVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDV 825
S L + + D + G Y C W K+ +W + AE S + I V V
Sbjct: 622 AESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPV 677
Score = 135 bits (341), Expect = 1e-31
Identities = 154/753 (20%), Positives = 276/753 (36%), Gaps = 84/753 (11%)
Query: 5 ASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSF--- 60
+ RP + ++ L L V V + V + G +L C+V P + + W
Sbjct: 394 SKRPKNIPIIVLPLKSSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDR 453
Query: 61 SSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
+ S+ + L V P Y ER G + + + ++ L I N + D+G Y+C
Sbjct: 454 QNRRSNIMWLDRDGTVQ-PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECH 512
Query: 121 TPSTDATVQGNYE--------DTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAA 172
V G ++ + + L V +R P + + F+L+C
Sbjct: 513 VTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTP---GVTYSDSFDLQCIIK 569
Query: 173 SASPLHTHLALLWEVHR-GPAR-RSVLALTHEGRFHPGLGYEQRYHSGDVRL---DTVGS 227
P +++ W G ++ T +G G+ + R S R S
Sbjct: 570 PHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDG----GVQWGDRSSSFRTRTAIEKAESS 625
Query: 228 DAYRLSVSRALSADQGSYRCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPKN 286
+ RLS+SRA + G Y+C+ W N W + E+ + + + V + V K+
Sbjct: 626 NNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKS 685
Query: 287 ---VSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSS 343
+++ E K + L C++ + + + V W + D+ +++ + +S
Sbjct: 686 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDAD---GKLILKTTHNSAFEYG 742
Query: 344 PHVALS----------HVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAV 393
+ HV + L V+ +SG YYCHV W N +W+K+AE V
Sbjct: 743 TYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEV 802
Query: 394 SSPAGVGVTWLEPDYQVYLNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRM 451
S V V +PD ++ L+ ++ + +L C V++ S + V W+
Sbjct: 803 SGRTEVTVK--QPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTS--ITSQLMVEWFVWK 858
Query: 452 NRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRG 511
+ E +A + D T YGE++ + G + IQ +D G
Sbjct: 859 PNHPER----ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSG 914
Query: 512 NYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTC 571
Y C V W + W K + + + D+ L V P + F++ C
Sbjct: 915 TYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDC 974
Query: 572 KVSSKNIKSPRYSVLIMA-------------------------EKPVGDLSSPNETKYII 606
+ S++ + R++V + E+ D P E ++
Sbjct: 975 SIVSRSSQDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALL 1034
Query: 607 SLDQDSVVKLEN--WTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVR 664
S+ D+V E W R +++ +R + Q D G Y C V W P
Sbjct: 1035 SVGPDAVFGPEGSPWEGRLR-----FQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSP 1089
Query: 665 GSLWREAATSLSNPIEIDFQTSGPIFNASVHSD 697
W S PI I + P + + S+
Sbjct: 1090 QKEWYRLTEEESAPIGIRVLDTSPTLQSIICSN 1122
Score = 126 bits (316), Expect = 1e-28
Identities = 131/588 (22%), Positives = 230/588 (39%), Gaps = 60/588 (10%)
Query: 3 RLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSS 62
R AS P+ + L + + R P T + +I + Y + W F
Sbjct: 530 RRASTPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPH---YPAWVPVSVTWRFQP 586
Query: 63 LGS-SFVELAS-TWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS 120
+G+ F +L + T + G + + + +++ V L I ++ G Y+C
Sbjct: 587 VGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCV 646
Query: 121 TP-------STDATVQGNYEDTVQVKVL--ADSLHVGPSARPPPSLSLREGEPFELRCTA 171
+T + + ++++VL L V S R +L+L E +P +L C+
Sbjct: 647 AELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKR---TLTLVENKPIQLNCSV 703
Query: 172 ASASPLHTHLALLWEVHRGPAR--RSVLALTHEGRFHPGLGYEQRYHSGDVRLDT-VGSD 228
S + ++H A+LW VH+ + +L TH F G E+ ++ + V
Sbjct: 704 KSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGG 763
Query: 229 AYRLSVSRALSADQGSYRCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPK-- 285
+ L+V RA +D GSY C V EW+ W ++ E+ V ++ R + +
Sbjct: 764 LFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQ 823
Query: 286 -NVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP 344
N+SV E +++ L C + + + V W F P+ P +ARL RD+ H
Sbjct: 824 GNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNH--PERETVARLSRDATFHYGE 880
Query: 345 HVALSHVDARS---------YHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSS 395
A +++ R Y L +++V+ ++SG Y CHV W P + W+K AE +
Sbjct: 881 QAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAG 940
Query: 396 PAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRR- 454
+ V + QV +L C +V S ++ RF V+WY +
Sbjct: 941 QTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDS--RFAVAWYSLRTKAG 998
Query: 455 --------SDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTD---------- 496
+ E D D ER+ + D +F E +
Sbjct: 999 GKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRL 1058
Query: 497 ---TFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNI 541
+ + + + +D GNY C V W W + + S P+ I
Sbjct: 1059 SPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGI 1106
>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
sapiens]
Length = 1214
Score = 245 bits (625), Expect = 1e-64
Identities = 218/858 (25%), Positives = 365/858 (42%), Gaps = 75/858 (8%)
Query: 8 PLLLALLSLALCRG-RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLG 64
P+L L L + R V V L R G+ + I CNVS Y GPSEQNF WS S
Sbjct: 6 PVLSCLAVLGVVSAQRQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSP 65
Query: 65 SSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPST 124
V++ ST + FP +Y +R++ G+I + R ++ LHI ++Q D G Y+C TPST
Sbjct: 66 EREVQIVSTMDSSFPYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPST 125
Query: 125 DATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALL 184
D G+Y + + V+ DSL + P +L E +P EL C AS + H+HL++
Sbjct: 126 DKQYFGSYSAKMNLVVIPDSLQ---TTAMPQTLHRVEQDPLELTCEVASETIQHSHLSVA 182
Query: 185 WEVHR-GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQG 243
W + G V++L+ + H Y QR G+VRLD +G +RL++ +DQG
Sbjct: 183 WLRQKVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQG 242
Query: 244 SYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLT 298
+ C +EWI + G+W + K E A V +QP+ +R K + G+ ++
Sbjct: 243 EFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTV-GEPVEFR 301
Query: 299 CNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHL 358
C + D V+W+F+ +T+ + V + + + ++ + L
Sbjct: 302 CILEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVL 361
Query: 359 LVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGV-------TW-------- 403
+ + +E+SG Y C V+ + + + P + + W
Sbjct: 362 KIYHLRQEDSGKYNCRVT--EREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHH 419
Query: 404 -------LEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYY--RMNRR 454
LE V + ++ + +C V +G RF+V W R NRR
Sbjct: 420 QLLSQGHLESSISVEVASNASVILEGEDLRFSCSV--RTAGRPQGRFSVIWQLVDRQNRR 477
Query: 455 SDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYY 514
S+ + +D D T++ G +R+ G + ++F+ I + +ED G Y
Sbjct: 478 SN-------IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYE 530
Query: 515 CVVSAWTKQRNNSW-VKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKV 573
C V+ W + + W + + S P++I ALE V A P ++F++ C
Sbjct: 531 CHVTEWVRAVDGEWQIVGERRASTPISI-TALEMG-FAVTAISRTPGVTYSDSFDLQC-- 586
Query: 574 SSKNIKSPRYSVLIMAE-----KPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGV 628
I P Y + +PVG + E +++ +D V+ + + + R
Sbjct: 587 ----IIKPHYPAWVPVSVTWRFQPVGTV----EFHDLVTFTRDGGVQWGDRSSSFRTRTA 638
Query: 629 VLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGP 688
+ + + R + + ++AG Y+C+ W + W A SN +EI
Sbjct: 639 IEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVT 698
Query: 689 IFNASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSS 748
S T +++ I+L C + + + + F V W+ VH ++L +
Sbjct: 699 KLQVSKSKRTLTLVENKPIQLNCSVKSQTS----QNSHFAVLWY-VHKPSDADGKLILKT 753
Query: 749 LDRKGI---VTTSRRDWKSDLSLER-VSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTG 804
++ L ER VS F L V +E D G+YYC V W+ SP
Sbjct: 754 THNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNY 813
Query: 805 SWQKEAEIHSKPVFITVK 822
+W K AE S +TVK
Sbjct: 814 AWYKLAEEVSGRTEVTVK 831
Score = 176 bits (446), Expect = 8e-44
Identities = 185/867 (21%), Positives = 322/867 (37%), Gaps = 90/867 (10%)
Query: 24 VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82
VR+ T + VG + C + + P W+F+S S + V
Sbjct: 283 VRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 339
Query: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDT------- 135
+ R RG++ + + ++ L I +++ D G Y C + TV G + D
Sbjct: 340 FAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKRPKN 399
Query: 136 --VQVKVLADS----------------LHVGPSARPPPSLS-LREGEPFELRCTAASASP 176
+ V L D+ L S + S + EGE C+ +A
Sbjct: 400 IPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSVRTAGR 459
Query: 177 LHTHLALLWE-VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVS 235
+++W+ V R R +++ L +G PG Y +R G V+++ V +++ L +
Sbjct: 460 PQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIF 519
Query: 236 RALSADQGSYRCIVSEWI-AEQGNWQEIQEK--AVEVATVVIQPSVLRAAVPKNVSVAEG 292
+ D+G Y C V+EW+ A G WQ + E+ + ++ ++ A+ + V
Sbjct: 520 NSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMGFAVTAISRTPGVTYS 579
Query: 293 KELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLAR------LDRDSLVHSSPHV 346
DL C I V VTW F + R DR S + +
Sbjct: 580 DSFDLQCIIKPHYPAWVPVSVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFRTRTAI 639
Query: 347 ALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEP 406
+ + + L + S +G Y C LW +N +W ++AE S+ + V L+P
Sbjct: 640 EKAE-SSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRV--LQP 696
Query: 407 DYQVYLNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELL 464
++ ++ SK + + P +L C V S N F V WY +++ SD +L+
Sbjct: 697 VTKLQVSKSKRTLTLVENKPIQLNCSVKSQTS--QNSHFAVLWY--VHKPSD--ADGKLI 750
Query: 465 AVMDGDWTLKYGERSKQRAQDGDFIFSKEHT-DTFNFRIQRTTEEDRGNYYCVVSAWTKQ 523
+ +YG +++ F + + F+ +QR D G+YYC V W
Sbjct: 751 LKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLS 810
Query: 524 RNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRY 583
N +W K + S + DS L + Q ++ C V ++ + +
Sbjct: 811 PNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQL 870
Query: 584 SVLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDG-VVLEKVQEDEFRYRM 642
V KP + E + + L +D+ + + G + LE +R +
Sbjct: 871 MVEWFVWKP-----NHPERETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFI 925
Query: 643 YQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVI 702
V D+G Y C V W P +W + A + + +V
Sbjct: 926 QNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALTVMRPDASLQVDTVVPNATVS 985
Query: 703 RGDLIKLFCIITVEGAALDPDDMAFDVSWFAVH--------SFGLDKAP----------- 743
+L C I + D F V+W+++ S GL++
Sbjct: 986 EKAAFQLDCSIVSRSS----QDSRFAVAWYSLRTKAGGKRSSPGLEEQEEEREEEEEEDD 1041
Query: 744 ---------VLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCS 794
L S+ + W+ L +R+S + + L V + QD GNY C
Sbjct: 1042 DDDDDPTERTALLSVGPDAVFGPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCH 1101
Query: 795 VTPWVKSPTGSWQKEAEIHSKPVFITV 821
V W+ SP W + E S P+ I V
Sbjct: 1102 VEEWLPSPQKEWYRLTEEESAPIGIRV 1128
Score = 151 bits (381), Expect = 3e-36
Identities = 192/841 (22%), Positives = 316/841 (37%), Gaps = 77/841 (9%)
Query: 30 TLVRVVGTELVIPCNV-SDYDGPSEQNFDWSFSSLGSSFVELASTWE--VGFPAQLYQER 86
TL RV L + C V S+ S + W +G VE+ S + + Y +R
Sbjct: 154 TLHRVEQDPLELTCEVASETIQHSHLSVAWLRQKVGEKPVEVISLSRDFMLHSSSEYAQR 213
Query: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
GE+ L + L I ++QPSDQG + C G++ + + ++
Sbjct: 214 QSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVN 273
Query: 147 VGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALT 200
V P+ + E GEP E RC + + + A+ W A S L T
Sbjct: 274 VQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNVPDRYFAVSW------AFNSSLIAT 327
Query: 201 HEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE-QG 257
P L E R G +++ + L + D G Y C V+E G
Sbjct: 328 MGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTG 387
Query: 258 NWQEIQEKAVEVATVVIQP----------------------SVLRAAVPKNVSVA-EGKE 294
+ + + K + +++ P S + V N SV EG++
Sbjct: 388 EFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGED 447
Query: 295 LDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPH 345
L +C++ T R V W ++ D S ++ LDRD V S
Sbjct: 448 LRFSCSVRTAGRPQGRFSVIW---QLVDRQNRRSNIMW-LDRDGTVQPGSSYWERSSFGG 503
Query: 346 VALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLE 405
V + V S+ L + + KE+ G Y CHV+ W + W V E +S + +T LE
Sbjct: 504 VQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTP-ISITALE 562
Query: 406 PDYQVYLNASKVPGFA-DDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELL 464
+ V S+ PG D +L C + A V +V+W ++ V L
Sbjct: 563 MGFAVTA-ISRTPGVTYSDSFDLQCII--KPHYPAWVPVSVTWRFQ----PVGTVEFHDL 615
Query: 465 AVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQR 524
D +++G+RS + I E ++ I R ++ + G Y CV W K
Sbjct: 616 VTFTRDGGVQWGDRSSS-FRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNY 674
Query: 525 NNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYS 584
NN+W + + S + I + L V + ++ C V S+ ++ ++
Sbjct: 675 NNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSVKSQTSQNSHFA 734
Query: 585 VLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVL--EKVQEDEFRYRM 642
VL KP S + K I+ +S + + + + + V F +
Sbjct: 735 VLWYVHKP-----SDADGKLILKTTHNSAFEYGTYAEEEGLRARLQFERHVSGGLFSLTV 789
Query: 643 YQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVI 702
+ +VSD+G Y C V W W + A +S E+ + S SV+
Sbjct: 790 QRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQGNLSVL 849
Query: 703 RGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIV--TTSRR 760
++L C++ + ++ M V WF ++ V S D ++
Sbjct: 850 ETRQVQLECVV-LNRTSITSQLM---VEWFVWKPNHPERETVARLSRDATFHYGEQAAKN 905
Query: 761 DWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFIT 820
+ K L LE S + L + QD G Y C V W+ SP+G W K AE + +T
Sbjct: 906 NLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTALT 965
Query: 821 V 821
V
Sbjct: 966 V 966
Score = 135 bits (339), Expect = 2e-31
Identities = 138/675 (20%), Positives = 247/675 (36%), Gaps = 79/675 (11%)
Query: 79 PAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE----- 133
P Y ER G + + + ++ L I N + D+G Y+C V G ++
Sbjct: 491 PGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGER 550
Query: 134 ---DTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVHR- 189
+ + L V +R P + + F+L+C P +++ W
Sbjct: 551 RASTPISITALEMGFAVTAISRTP---GVTYSDSFDLQCIIKPHYPAWVPVSVTWRFQPV 607
Query: 190 GPAR-RSVLALTHEGRFHPGLGYEQRYHSGDVRL---DTVGSDAYRLSVSRALSADQGSY 245
G ++ T +G G+ + R S R S+ RLS+SRA + G Y
Sbjct: 608 GTVEFHDLVTFTRDG----GVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKY 663
Query: 246 RCIVSEWIAEQGN-WQEIQEKAVEVATVVIQPSVLRAAVPKN---VSVAEGKELDLTCNI 301
+C+ W N W + E+ + + + V + V K+ +++ E K + L C++
Sbjct: 664 QCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKPIQLNCSV 723
Query: 302 TTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALS----------HV 351
+ + + V W + D+ +++ + +S + HV
Sbjct: 724 KSQTSQNSHFAVLWYVHKPSDAD---GKLILKTTHNSAFEYGTYAEEEGLRARLQFERHV 780
Query: 352 DARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVY 411
+ L V+ +SG YYCHV W N +W+K+AE VS V V +PD ++
Sbjct: 781 SGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVK--QPDSRLR 838
Query: 412 LNASK--VPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDG 469
L+ ++ + +L C V++ S + V W+ + E +A +
Sbjct: 839 LSQAQGNLSVLETRQVQLECVVLNRTS--ITSQLMVEWFVWKPNHPER----ETVARLSR 892
Query: 470 DWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV 529
D T YGE++ + G + IQ +D G Y C V W + W
Sbjct: 893 DATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWY 952
Query: 530 KSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMA 589
K + + + D+ L V P + F++ C + S++ + R++V +
Sbjct: 953 KRAEDTAGQTALTVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYS 1012
Query: 590 -------------------------EKPVGDLSSPNETKYIISLDQDSVVKLEN--WTDA 622
E+ D P E ++S+ D+V E W
Sbjct: 1013 LRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWEGR 1072
Query: 623 SRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEID 682
R +++ +R + Q D G Y C V W P W S PI I
Sbjct: 1073 LR-----FQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESAPIGIR 1127
Query: 683 FQTSGPIFNASVHSD 697
+ P + + S+
Sbjct: 1128 VLDTSPTLQSIICSN 1142
Score = 130 bits (326), Expect = 7e-30
Identities = 147/676 (21%), Positives = 250/676 (36%), Gaps = 70/676 (10%)
Query: 185 WEVH--RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQ 242
W ++ P R + T + F P Y QR G + ++ V ++ L ++ + D
Sbjct: 57 WSIYLPSSPEREVQIVSTMDSSF-PYAIYTQRVRGGKIFIERVQGNSTLLHITDLQARDA 115
Query: 243 GSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNIT 302
G Y C + Q + ++ VVI S+ A+P+ + E L+LTC +
Sbjct: 116 GEYECHTPST-----DKQYFGSYSAKMNLVVIPDSLQTTAMPQTLHRVEQDPLELTCEVA 170
Query: 303 TDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVA---------LSHVDA 353
++ V W ++ + + + L RD ++HSS A L +
Sbjct: 171 SETIQHSHLSVAWLRQKVGEKPVE----VISLSRDFMLHSSSEYAQRQSLGEVRLDKLGR 226
Query: 354 RSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLN 413
++ L + + + G +YC + W + SW+ + S A V V + ++ V L
Sbjct: 227 TTFRLTIFHLQPSDQGEFYCEAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLE 286
Query: 414 ASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTL 473
K +P E C + + F VSW + S L+A M +
Sbjct: 287 TEKRLHTVGEPVEFRC--ILEAQNVPDRYFAVSWAFN----------SSLIATMGPNAVP 334
Query: 474 KYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV---- 529
R G +KE F +I +ED G Y C V+ K ++
Sbjct: 335 VLNSEFAHREARGQLKVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKES 394
Query: 530 ---KSKDVFSKPVNIFWALE-------------DSVLVVKARQPKPFFAAGNTFEMTCKV 573
K+ + P+ W ++ +S + V+ G +C V
Sbjct: 395 KRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGHLESSISVEVASNASVILEGEDLRFSCSV 454
Query: 574 SSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEK 632
+ R+SV+ + N I+ LD+D V+ ++ + S GV +E+
Sbjct: 455 RTAGRPQGRFSVIWQL------VDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQMEQ 508
Query: 633 VQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATS-LSNPIEIDFQTSGPIFN 691
VQ + F ++ ++ D G Y C VT W W+ S PI I G F
Sbjct: 509 VQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITALEMG--FA 566
Query: 692 ASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDR 751
+ S TP V D L CII A P V+W G + L++
Sbjct: 567 VTAISRTPGVTYSDSFDLQCIIKPHYPAWVP----VSVTW-RFQPVGTVEFHDLVTFTRD 621
Query: 752 KGIVTTSRRD-WKSDLSLERV-SVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKE 809
G+ R +++ ++E+ S L + + D + G Y C W K+ +W +
Sbjct: 622 GGVQWGDRSSSFRTRTAIEKAESSNNVRLSISRASDTEAGKYQCVAELWRKNYNNTWTRL 681
Query: 810 AEIHSKPVFITVKMDV 825
AE S + I V V
Sbjct: 682 AERTSNLLEIRVLQPV 697
>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
Length = 613
Score = 228 bits (581), Expect = 2e-59
Identities = 163/565 (28%), Positives = 260/565 (46%), Gaps = 33/565 (5%)
Query: 6 SRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSL 63
S PLLL L+ C R V VP L RV GT + I CNV+ Y+GP++QNF+W
Sbjct: 12 SLPLLLLLMLGMGCWAREVLVPEGPLYRVAGTAVSISCNVTGYEGPAQQNFEWFLYRPEA 71
Query: 64 GSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPS 123
+ + + ST + F +++ R+ GE+ ++R DAV L I +Q D G Y+C TPS
Sbjct: 72 PDTALGIVSTKDTQFSYAVFKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPS 131
Query: 124 TDATVQGNYEDTVQVKVLADSLHV-----GPSAR----PPPSLSLREGEPFELRCTAASA 174
TD G+Y V+++VL D L V GP R PP +++ EG+ L C A ++
Sbjct: 132 TDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTS 191
Query: 175 SPLHTHLALLW--EVHRGPARRS----VLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSD 228
+ HTHLA+ + V P RS V+ + + G Y +R +G++RL G+D
Sbjct: 192 TQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTD 251
Query: 229 AYRLSVSRALSADQGSYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPSVLRAAV---P 284
YR+ V A + D G+Y C +EWI + G+W +I EK +A V +Q + AV P
Sbjct: 252 RYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGP 311
Query: 285 KNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPG-SRVLARLDRDSLVHSS 343
+ G+ L+L CN++ R M + PG R++A+LD + +
Sbjct: 312 GERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLG 371
Query: 344 P-----HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAG 398
P H+A+ V +R+Y L + ++G Y C + G + A A S P
Sbjct: 372 PGYEGRHIAMEKVASRTYRLRLEAARPGDAGTYRCLAKAYVRGSGTRLREAASARSRPLP 431
Query: 399 VGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSD-N 457
V V + + + + L C + + G +R SW+ + +
Sbjct: 432 VHVREEGVVLEAVAWLAGGTVYRGETASLLCN-ISVRGGPPGLRLAASWWVERPEDGELS 490
Query: 458 VVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVV 517
V ++L+ + D + G R + + + H R+ ED G Y+C
Sbjct: 491 SVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGPRSH----RLRLHSLGPEDEGVYHCAP 546
Query: 518 SAWTKQRNNSWVKSKDVFSKPVNIF 542
SAW + + SW ++ S PV ++
Sbjct: 547 SAWVQHADYSWYQAGSARSGPVTVY 571
Score = 129 bits (325), Expect = 9e-30
Identities = 110/500 (22%), Positives = 201/500 (40%), Gaps = 16/500 (3%)
Query: 358 LLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKV 417
L + + +++G Y CH + S+ E P + V+ P + +
Sbjct: 112 LKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSAAPPGPRGRQAPTSP 171
Query: 418 PGFA-DDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYG 476
P + ELA + S + + VS+ + T + + + D ++ G
Sbjct: 172 PRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQEVVGIRSDLAVEAG 231
Query: 477 ERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFS 536
+R G+ KE TD + + D G Y+C + W + + SW + + +
Sbjct: 232 APYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQDPDGSWAQIAEKRA 291
Query: 537 KPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDL 596
++ S L V + G E+ C VS + R++ + + +
Sbjct: 292 VLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGRHAAYSVGWE-MAPA 350
Query: 597 SSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCM 656
+P + + LD + V L + + +EKV +R R+ + DAG YRC+
Sbjct: 351 GAPGPGRLVAQLDTEGVGSLGPGYEGRHI---AMEKVASRTYRLRLEAARPGDAGTYRCL 407
Query: 657 VTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVE 716
A+ G+ REAA++ S P+ + + G + A +V RG+ L C I+V
Sbjct: 408 AKAYVRGSGTRLREAASARSRPLPVHVREEGVVLEAVAWLAGGTVYRGETASLLCNISVR 467
Query: 717 GAALDPDDMAFDVSWFAVHSFGLDKAPV---LLSSLDRKGIVTTSRRDWKSDLSLERVSV 773
G P + SW+ + + V L+ + + G+ R +S+E V
Sbjct: 468 GG---PPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELGVRPGGGPVSVELVGP 524
Query: 774 LEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITVKMDVLNAFKYPL 833
L++H +D G Y+C+ + WV+ SW + S PV + M L+ PL
Sbjct: 525 RSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSARSGPVTVYPYMHALDTLFVPL 584
Query: 834 LIGVGL-----STVIGLLSC 848
L+G G+ +TV+G ++C
Sbjct: 585 LVGTGVALVTGATVLGTITC 604
>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
Length = 1021
Score = 227 bits (579), Expect = 3e-59
Identities = 210/831 (25%), Positives = 365/831 (43%), Gaps = 64/831 (7%)
Query: 4 LASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWS--FS 61
+AS LLL LS+ R V V L R G + I CNV+ + GPSEQ+F WS
Sbjct: 7 VASFFLLLTKLSIGQ---REVTVQKGPLFRAEGYPVSIGCNVTGHQGPSEQHFQWSVYLP 63
Query: 62 SLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCST 121
+ + V++ ST + F +Y +R++ G++ + R ++V LHI +Q D G Y+C T
Sbjct: 64 TNPTQEVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHT 123
Query: 122 PSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHL 181
P+TD G+Y + V+ D+L S++ +L EGEP L C A+ A+ HTHL
Sbjct: 124 PNTDEKYYGSYSAKTNLIVIPDTLSATMSSQ---TLGKEEGEPLALTCEASKATAQHTHL 180
Query: 182 ALLWEVHR---GPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRAL 238
++ W + + G +++L+ + PG Y +R+ + DV+L+ +G +RLS+ R
Sbjct: 181 SVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQ 240
Query: 239 SADQGSYRCIVSEWIAE-QGNWQEIQEKAVEVATVVIQPSV--LRAAVPKNVSVAEGKEL 295
S+DQG C +EWI + W I +K + T+ IQP+V + + + AEGK L
Sbjct: 241 SSDQGQLFCEATEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNITADSLFAEGKPL 300
Query: 296 DLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARS 355
+L C + D + + W F+ + + VL + S + +S + ++
Sbjct: 301 ELVC-LVVSSGRDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKA 359
Query: 356 YHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNAS 415
+ L + + E+ G Y C V+ SW + S + V + V +
Sbjct: 360 FSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKN 419
Query: 416 KVPGFADDPT-ELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLK 474
K + T C K+G A +VSW++ ++ E +A M D ++
Sbjct: 420 KQQVVWEGETLAFLC-----KAGGAESPLSVSWWHIPRDQTQ----PEFVAGMGQDGIVQ 470
Query: 475 YGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQ--RNNSWVKSK 532
G + G+ K TF I T D G Y C VS ++ R+ SW +
Sbjct: 471 LGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKI 530
Query: 533 DVFSKPVNIFWALEDSVLV-VKARQPKPFFAAGNTFEMTCKVSS--KNIKSPRYSVLIMA 589
V K +LE S+ V + +RQP+ NTF+++C V + ++K P +
Sbjct: 531 SVTVK------SLESSLQVSLMSRQPQVMLT--NTFDLSCVVRAGYSDLKVP--LTVTWQ 580
Query: 590 EKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRM--YQTQV 647
+P +S + +I + + ++ N+ + KV + FR ++ +
Sbjct: 581 FQP----ASSHIFHQLIRITHNGTIEWGNFLSRFQKK----TKVSQSLFRSQLLVHDATE 632
Query: 648 SDAGLYRCMVTAWSPVRGSLWRE---AATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRG 704
+ G+Y+C V + R SL+ A+++S+P+ I + S +
Sbjct: 633 EETGVYQCEVEVYD--RNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSIN 690
Query: 705 DLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRR---- 760
+ C I + ++ + W+ + + + + +D+ ++ T
Sbjct: 691 SNTDIECSI----LSRSNGNLQLAIIWY-FSPVSTNASWLKILEMDQTNVIKTGDEFHTP 745
Query: 761 DWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAE 811
K E+VS F L + ED D G Y+C+V W+ S G+W K E
Sbjct: 746 QRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGE 796
Score = 147 bits (370), Expect = 6e-35
Identities = 188/835 (22%), Positives = 330/835 (39%), Gaps = 112/835 (13%)
Query: 79 PAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCS------------------ 120
P LY ER ++ L + L I+ +Q SDQG C
Sbjct: 209 PGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEATEWIQDPDETWMFITKK 268
Query: 121 -TPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHT 179
T T +Q +D QV + ADSL EG+P EL C S S
Sbjct: 269 QTDQTTLRIQPAVKD-FQVNITADSLFA-------------EGKPLELVCLVVS-SGRDP 313
Query: 180 HLALLWEVHRGPARR----SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVS 235
L +W + VL L ++ Y++R G++++ +G A+ L +
Sbjct: 314 QLQGIWFFNGTEIAHIDAGGVLGLKND--------YKERASQGELQVSKLGPKAFSLKIF 365
Query: 236 RALSADQGSYRCIVSEWIAEQ-GNWQEIQEKAVEVATVVIQPSVLRAAVP----KNVSVA 290
D+G+YRC+V+E + + G+WQ +Q K + V ++ R+ V K V
Sbjct: 366 SLGPEDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVW 425
Query: 291 EGKELDLTCNITTDRADDVRPEVTWSFSRMP-DSTLPGSRVLARLDRDSLVHSSP----- 344
EG+ L C +A ++ S+ +P D T P +A + +D +V
Sbjct: 426 EGETLAFLC-----KAGGAESPLSVSWWHIPRDQTQP--EFVAGMGQDGIVQLGASYGVP 478
Query: 345 ----HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNR--SW-HKVAEAVSSPA 397
+ L +D ++ L + + +SG Y C VS + R SW K++ V S
Sbjct: 479 SYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSEKSRNQARDLSWTQKISVTVKS-- 536
Query: 398 GVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDN 457
LE QV L + + + +L+C VV + V TV+W ++ + +
Sbjct: 537 ------LESSLQVSLMSRQPQVMLTNTFDLSC-VVRAGYSDLKVPLTVTWQFQP---ASS 586
Query: 458 VVTSELLAVMDGDWTLKYGE---RSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYY 514
+ +L+ + T+++G R +++ + +F + + TEE+ G Y
Sbjct: 587 HIFHQLIRITHNG-TIEWGNFLSRFQKKTKVSQSLFRSQ------LLVHDATEEETGVYQ 639
Query: 515 CVVSAWTKQR-NNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKV 573
C V + + N+ S P+ I L +S L V +R + + ++ C +
Sbjct: 640 CEVEVYDRNSLYNNRPPRASAISHPLRIAVTLPESKLKVNSRSQVQELSINSNTDIECSI 699
Query: 574 SSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEK 632
S++ + + ++ I PV +S + I+ +DQ +V+K + + R EK
Sbjct: 700 LSRSNGNLQLAI-IWYFSPVSTNASWLK---ILEMDQTNVIKTGDEFHTPQRKQKFHTEK 755
Query: 633 VQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNA 692
V +D F+ + + SD G Y C V W W + S E+ + +G
Sbjct: 756 VSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRV 815
Query: 693 SVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRK 752
S T +V + + C + G++ + V W+ + LL L
Sbjct: 816 SKVYWTENVTEHREVAIRCSLESVGSSA----TLYSVMWYWNRE---NSGSKLLVHLQHD 868
Query: 753 GIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPW-VKSPTGSWQKEAE 811
G++ + L R S +F+L++H E +D G Y+C V W + W +A
Sbjct: 869 GLLEYGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQAS 928
Query: 812 IHSKPVFITV-----KMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKK 861
S+ + +TV + PLL + + + LL LI +W +K
Sbjct: 929 DESQRMVLTVLPSEPTLPSRICSSAPLLYFLFICPFVLLLLLLISLLCLYWKARK 983
>gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 376
Score = 93.2 bits (230), Expect = 9e-19
Identities = 79/354 (22%), Positives = 150/354 (42%), Gaps = 18/354 (5%)
Query: 196 VLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE 255
V++L+ + H G Y R G+VRLD +G +RL++ +DQG + C +EWI
Sbjct: 28 VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
Query: 256 -QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLTCNITTDRADDVR 310
G+W + K E A V +QP+ +R K + + G+ ++ C D
Sbjct: 88 PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMV-GEPVEFRCIPEAQNVPDRY 146
Query: 311 PEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGY 370
V+W+F+ +T+ + V + + + ++ + L + + +E+SG
Sbjct: 147 FAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGK 206
Query: 371 YYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACR 430
Y C V+ + + + P + + L + + + + + +L
Sbjct: 207 YNCRVT--EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFS 264
Query: 431 VVDTKSGEANVRFTVSWYY--RMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDF 488
+G RF+V W R NRRSD + +D D T++ G +R+ G
Sbjct: 265 CSVRMAGRPQGRFSVIWQLVDRQNRRSD-------IMWLDRDGTVQPGSSYWERSSFGSV 317
Query: 489 IFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSW-VKSKDVFSKPVNI 541
+ ++F+ I + +ED G Y C V+ W + + W + + S P++I
Sbjct: 318 QMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISI 371
Score = 92.0 bits (227), Expect = 2e-18
Identities = 81/358 (22%), Positives = 132/358 (36%), Gaps = 33/358 (9%)
Query: 334 LDRDSLVHSSPHVA---------LSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNR 384
L RD ++HS A L + ++ L + + + G +YC + W +
Sbjct: 31 LSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDG 90
Query: 385 SWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFT 444
SW+ + S A V V E ++ V L K +P E C + + F
Sbjct: 91 SWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRC--IPEAQNVPDRYFA 148
Query: 445 VSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQR 504
VSW + S L+A M + R G +KE F +I
Sbjct: 149 VSWAFN----------SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYH 198
Query: 505 TTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAG 564
+ED G Y C V+ K ++ + K + I +S + V+ G
Sbjct: 199 LRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEG 258
Query: 565 NTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDAS 623
+C V R+SV+ + N I+ LD+D V+ ++ + S
Sbjct: 259 EDLRFSCSVRMAGRPQGRFSVIWQL------VDRQNRRSDIMWLDRDGTVQPGSSYWERS 312
Query: 624 RVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLW-----REAATSLS 676
V +E+VQ + F ++ ++ D G Y C VT W V W R A+T +S
Sbjct: 313 SFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPIS 370
Score = 80.1 bits (196), Expect = 8e-15
Identities = 60/261 (22%), Positives = 107/261 (40%), Gaps = 14/261 (5%)
Query: 24 VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82
VR+ T + +VG + C + P W+F+S S + V
Sbjct: 116 VRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 172
Query: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYED-------T 135
+ R RG++ + + ++ L I +++ D G Y C + TV G + D
Sbjct: 173 FAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
Query: 136 VQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARR 194
+ + VL + S+ L EGE C+ A +++W+ V R R
Sbjct: 233 IPIIVLPLESSISVEVASNASVIL-EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRS 291
Query: 195 SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI- 253
++ L +G PG Y +R G V+++ V +++ L + + D+G Y C V+EW+
Sbjct: 292 DIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR 351
Query: 254 AEQGNWQEIQEKAVEVATVVI 274
G WQ + E+ +I
Sbjct: 352 VVDGEWQIVGERRASTPISII 372
Score = 70.9 bits (172), Expect = 5e-12
Identities = 71/343 (20%), Positives = 120/343 (34%), Gaps = 23/343 (6%)
Query: 470 DWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV 529
D+ L G R G+ K TF I D+G +YC + W + + SW
Sbjct: 34 DFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWY 93
Query: 530 KSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMA 589
S+ + + V+ K G E C ++N+ ++V
Sbjct: 94 AMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAV---- 149
Query: 590 EKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVV-LEKVQEDEFRYRMYQTQVS 648
S + I ++ ++V L + G + + K + F ++Y +
Sbjct: 150 -------SWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQE 202
Query: 649 DAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIK 708
D+G Y C VT + + + I I + V S+ ++ G+ ++
Sbjct: 203 DSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLR 262
Query: 709 LFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWK----S 764
C + + G F V W V + LDR G V W+
Sbjct: 263 FSCSVRMAGRPQG----RFSVIWQLVDRQNRRSD---IMWLDRDGTVQPGSSYWERSSFG 315
Query: 765 DLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQ 807
+ +E+V F L + S +D G Y C VT WV+ G WQ
Sbjct: 316 SVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQ 358
Score = 70.9 bits (172), Expect = 5e-12
Identities = 81/334 (24%), Positives = 128/334 (38%), Gaps = 31/334 (9%)
Query: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLA 142
Y R GE+ L + L I ++QPSDQG + C G++ + +
Sbjct: 43 YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102
Query: 143 DSLHVGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSV 196
++V P+ + E GEP E RC + + + A+ W A S
Sbjct: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSW------AFNSS 156
Query: 197 LALTHEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSE-WI 253
L T P L E R G + + + L + D G Y C V+E
Sbjct: 157 LIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216
Query: 254 AEQGNWQEIQEKAVEVATVVIQP--SVLRAAVPKNVSV-AEGKELDLTCNITTDRADDVR 310
G + + + K + +++ P S + V N SV EG++L +C++ R
Sbjct: 217 TVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGR 276
Query: 311 PEVTWSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPHVALSHVDARSYHLLVR 361
V W ++ D S ++ LDRD V S V + V S+ L +
Sbjct: 277 FSVIW---QLVDRQNRRSDIM-WLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332
Query: 362 DVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSS 395
+ KE+ G Y CHV+ W + W V E +S
Sbjct: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRAS 366
Score = 56.6 bits (135), Expect = 1e-07
Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 17/237 (7%)
Query: 590 EKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEKVQEDEFRYRMYQTQVS 648
E P+ + +ISL +D ++ + + V L+K+ FR ++ Q S
Sbjct: 13 EGPLAPCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPS 72
Query: 649 DAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIK 708
D G + C W W S ++ Q + F + ++ + G+ ++
Sbjct: 73 DQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVE 132
Query: 709 LFCIITVEGAALDPDDMAFDVSWF----AVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKS 764
CI + D F VSW + + G + PVL S + R+ +
Sbjct: 133 FRCIPEAQNVP----DRYFAVSWAFNSSLIATMGPNAVPVLNSEF--------AHREARG 180
Query: 765 DLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITV 821
L++ + S F+L+++ +D G Y C VT K+ TG + + H K + I V
Sbjct: 181 QLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIV 237
Score = 39.7 bits (91), Expect = 0.012
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 4/84 (4%)
Query: 743 PVLLSSLDRKGIVTT-SRRDWKSDLS---LERVSVLEFLLQVHGSEDQDFGNYYCSVTPW 798
PV + SL R ++ + S W+ L L+++ F L + + D G +YC W
Sbjct: 25 PVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEW 84
Query: 799 VKSPTGSWQKEAEIHSKPVFITVK 822
+++P GSW S+ + V+
Sbjct: 85 IQNPDGSWYAMTRKRSEGAVVNVQ 108
>gi|169215606 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
Length = 195
Score = 86.7 bits (213), Expect = 9e-17
Identities = 45/112 (40%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
Query: 22 RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLGSSFVELASTWEVGFP 79
R V V L R G+ + I CNVS Y GPSEQNF WS S V++ ST + FP
Sbjct: 84 RQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFP 143
Query: 80 AQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGN 131
+Y +R++ G+I + R + LHI ++Q D G Y+C TPST+ G+
Sbjct: 144 YAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 195
>gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]
Length = 155
Score = 86.7 bits (213), Expect = 9e-17
Identities = 45/112 (40%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
Query: 22 RVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSF--SSLGSSFVELASTWEVGFP 79
R V V L R G+ + I CNVS Y GPSEQNF WS S V++ ST + FP
Sbjct: 44 RQVTVQEGPLYRTEGSHITIWCNVSGYQGPSEQNFQWSIYLPSSPEREVQIVSTMDSSFP 103
Query: 80 AQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGN 131
+Y +R++ G+I + R + LHI ++Q D G Y+C TPST+ G+
Sbjct: 104 YAIYTQRVRGGKIFIERVQGNPTLLHITDLQARDAGEYECHTPSTEKQYFGS 155
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 50.8 bits (120), Expect = 5e-06
Identities = 77/349 (22%), Positives = 119/349 (34%), Gaps = 90/349 (25%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSA----RPPPSLSL 159
L +KN+ SD G Y C + Y+ +V H PS R P ++S+
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSV---------HAPPSIIGNHRSPENISV 2398
Query: 160 REGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGD 219
E L C A S PL + + W P S
Sbjct: 2399 VEKNSVSLTCEA-SGIPLPS---ITWFKDGWPVSLS----------------------NS 2432
Query: 220 VRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVL 279
VR+ + G L + + D G Y C+V E E+ + +V++ P ++
Sbjct: 2433 VRILSGGR---MLRLMQTTMEDAGQYTCVVRNAAGE--------ERKIFGLSVLVPPHIV 2481
Query: 280 RAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSL 339
++V V E + + LTC +T + PE+TW P L
Sbjct: 2482 GENTLEDVKVKEKQSVTLTCEVTGNPV----PEITWHKDGQP-----------------L 2520
Query: 340 VHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGV 399
H H+ + L + +V ++G Y C S A +RS+ + AGV
Sbjct: 2521 QEDEAH----HIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGV 2576
Query: 400 GVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWY 448
G D V LN+ PT L C T++W+
Sbjct: 2577 GSDGNPEDVTVILNS---------PTSLVCEAYSYPPA------TITWF 2610
Score = 48.9 bits (115), Expect = 2e-05
Identities = 53/203 (26%), Positives = 77/203 (37%), Gaps = 46/203 (22%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSL 159
D LHIK + SD G Y C + N+ V +V PS P +
Sbjct: 3111 DGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNV---------YVPPSIEGPEREVI 3161
Query: 160 RE--GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHS 217
E P L C A P ++ L + R E R S
Sbjct: 3162 VETISNPVTLTCDATGIPP-----------------PTIAWLKNHKRIENSDSLEVRILS 3204
Query: 218 GDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPS 277
G GS +L ++R+ +D G+Y CI S +G Q+ +++V PS
Sbjct: 3205 G-------GS---KLQIARSQHSDSGNYTCIASNM---EGKAQKYYFLSIQV-----PPS 3246
Query: 278 VLRAAVPKNVSVAEGKELDLTCN 300
V A +P +VSV G+ ++L CN
Sbjct: 3247 VAGAEIPSDVSVLLGENVELVCN 3269
Score = 40.4 bits (93), Expect = 0.007
Identities = 64/283 (22%), Positives = 109/283 (38%), Gaps = 80/283 (28%)
Query: 94 LRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARP 153
+R+ + L I VQP D GHY C A V G+ + ++ V HV P R
Sbjct: 4123 IRQRVLSSGSLQIAFVQPGDAGHYTCMA----ANVAGSSSTSTKLTV-----HVPPRIRS 4173
Query: 154 PPS-LSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYE 212
++ E L C A A+ W+ + +VL G++
Sbjct: 4174 TEGHYTVNENSQAILPCVADGIPTP----AINWK------KDNVLLANLLGKYTA----- 4218
Query: 213 QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATV 272
+ Y G++ L+ V + D G Y C+ + E + + TV
Sbjct: 4219 EPY--GELILENV------------VLEDSGFYTCVANNAAGEDTHTVSL--------TV 4256
Query: 273 VIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLA 332
+ P+ +P +VS+ +G++L L+C T P++TW+F+
Sbjct: 4257 HVLPTFTE--LPGDVSLNKGEQLRLSCKATGIPL----PKLTWTFNN------------- 4297
Query: 333 RLDRDSLVHSSPHVALSHVDARSYH--LLVRDVSKENSGYYYC 373
++ +H D+ + H L++ VSKE+SG Y C
Sbjct: 4298 ------------NIIPAHFDSVNGHSELVIERVSKEDSGTYVC 4328
Score = 36.6 bits (83), Expect = 0.11
Identities = 64/289 (22%), Positives = 102/289 (35%), Gaps = 52/289 (17%)
Query: 48 YDGPSEQNFDWSFSSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVE---- 103
Y P+ + + S L S VEL + P L L+ G LL++ E
Sbjct: 2101 YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTW--LKDGHPLLKKPGLSISENRSV 2158
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGE 163
L I++ Q D G Y C + + NY + V ++G S L++ EG
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP-----NIGGSDE-LTQLTVIEGN 2212
Query: 164 PFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLD 223
L C ++ P + L+W+ P + G VR+
Sbjct: 2213 LISLLCESSGIPPPN----LIWKKKGSPVLTDSM--------------------GRVRIL 2248
Query: 224 TVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA-A 282
+ G +L +S A +D Y C+ S +Q V I+P++ + +
Sbjct: 2249 SGGR---QLQISIAEKSDAALYSCVASNVAGTAKKEYNLQ--------VYIRPTITNSGS 2297
Query: 283 VPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVL 331
P + V GK + L C + P VTW P G +L
Sbjct: 2298 HPTEIIVTRGKSISLECEV----QGIPPPTVTWMKDGHPLIKAKGVEIL 2342
Score = 36.2 bits (82), Expect = 0.14
Identities = 50/220 (22%), Positives = 83/220 (37%), Gaps = 50/220 (22%)
Query: 101 AVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLR 160
+V L I V SD+G Y+C S+ T + + D P + P ++++
Sbjct: 481 SVNLDIAKVTLSDEGFYECIAVSSAGTGRA--------QTFFDVSEPPPVIQVPNNVTVT 532
Query: 161 EGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDV 220
GE L C SA + L W+ + R + A
Sbjct: 533 PGERAVLTCLIISAVDYN----LTWQRNDRDVRLAEPA---------------------- 566
Query: 221 RLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLR 280
R+ T+ + L + D G Y C+VS +E G+ A V V +P +
Sbjct: 567 RIRTLAN--LSLELKSVKFNDAGEYHCMVS---SEGGS------SAASVFLTVQEPPKV- 614
Query: 281 AAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRM 320
+PKN S G E+ + C+ T +P++ W+ + M
Sbjct: 615 TVMPKNQSFTGGSEVSIMCSAT----GYPKPKIAWTVNDM 650
Score = 36.2 bits (82), Expect = 0.14
Identities = 39/173 (22%), Positives = 64/173 (36%), Gaps = 35/173 (20%)
Query: 85 ERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADS 144
+R++ + L R + +L I Q SD G+Y C + + Q Y ++QV
Sbjct: 3190 KRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSV-- 3247
Query: 145 LHVGPSARPPPSLSLREGEPFELRCTA-ASASPLHTHLALLWEVHRGPARRSVLALTHEG 203
A P +S+ GE EL C A +PL + W P
Sbjct: 3248 ----AGAEIPSDVSVLLGENVELVCNANGIPTPL-----IQWLKDGKPIA---------- 3288
Query: 204 RFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQ 256
SG+ V ++ L++ AL++D G Y C+ + E+
Sbjct: 3289 -------------SGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 33.9 bits (76), Expect = 0.68
Identities = 52/220 (23%), Positives = 84/220 (38%), Gaps = 57/220 (25%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPS-LSLREG 162
LHI+ VQ D G Y C + V G T V V HV P+ + LS EG
Sbjct: 945 LHIERVQLQDGGEYTC----VASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 163 EPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRL 222
P L C A+ + +++W +++ L T +F G G + +
Sbjct: 996 IPVTLPCKASG----NPKPSVIW------SKKGELISTSSAKFSAGA-------DGSLYV 1038
Query: 223 DTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV---- 278
+ G + + G Y C + N ++ V++ TV ++P V
Sbjct: 1039 VSPGGE------------ESGEYVCTAT-------NTAGYAKRKVQL-TVYVRPRVFGDQ 1078
Query: 279 --LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWS 316
L P +SV G+E+ L C + + P +TW+
Sbjct: 1079 RGLSQDKPVEISVLAGEEVTLPCEVKSLPP----PIITWA 1114
Score = 32.0 bits (71), Expect = 2.6
Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 54/190 (28%)
Query: 224 TVGSDAY-------RLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
T+G D Y L +++ +D+G Y CI ++ G + V VIQ
Sbjct: 469 TLGVDQYLKESASVNLDIAKVTLSDEGFYECIA---VSSAGTGRAQTFFDVSEPPPVIQ- 524
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
VP NV+V G+ LTC I + V +TW R DR
Sbjct: 525 ------VPNNVTVTPGERAVLTCLIIS----AVDYNLTWQ----------------RNDR 558
Query: 337 DSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSP 396
D + + + L ++ V ++G Y+C VS +E SS
Sbjct: 559 DVRLAEPARIR----TLANLSLELKSVKFNDAGEYHCMVS-------------SEGGSSA 601
Query: 397 AGVGVTWLEP 406
A V +T EP
Sbjct: 602 ASVFLTVQEP 611
Score = 31.2 bits (69), Expect = 4.4
Identities = 53/213 (24%), Positives = 79/213 (37%), Gaps = 49/213 (23%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGE 163
L I N+ SD+G Y C + +Q E TV V L L +G S P ++ EG+
Sbjct: 852 LFILNLWASDKGTYICEAENQFGKIQS--ETTVTVTGLVAPL-IGIS---PSVANVIEGQ 905
Query: 164 PFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLD 223
L CT + +P+ P RR + + + + Y
Sbjct: 906 QLTLPCTLLAGNPI-------------PERRWIK--------NSAMLLQNPY-------I 937
Query: 224 TVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAV 283
TV SD L + R D G Y C+ S N K V V+ P++
Sbjct: 938 TVRSDG-SLHIERVQLQDGGEYTCVAS-------NVAGTNNKTTSVVVHVL-PTIQHG-- 986
Query: 284 PKNVSVAEGKELDLTCNITTDRADDVRPEVTWS 316
+ +S EG + L C + + +P V WS
Sbjct: 987 QQILSTIEGIPVTLPCK----ASGNPKPSVIWS 1015
Score = 31.2 bits (69), Expect = 4.4
Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 10/81 (12%)
Query: 92 ILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPS- 150
+L + TA EL ++NV D G Y C + EDT V + ++HV P+
Sbjct: 4212 LLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG------EDTHTVSL---TVHVLPTF 4262
Query: 151 ARPPPSLSLREGEPFELRCTA 171
P +SL +GE L C A
Sbjct: 4263 TELPGDVSLNKGEQLRLSCKA 4283
>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
[Homo sapiens]
Length = 785
Score = 49.7 bits (117), Expect = 1e-05
Identities = 74/336 (22%), Positives = 131/336 (38%), Gaps = 53/336 (15%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKV-LADSLHVGPSARPP 154
RT E+ +++ P+D G Y C T S + DT V ++D+L
Sbjct: 78 RTRITGEEVEVQDSVPADSGLYACVTSSPSGS------DTTYFSVNVSDALPSSEDDDDD 131
Query: 155 PSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARRSV-LALTHEGRFHPGL--- 209
S E E + +P T + + +H PA ++V G +P L
Sbjct: 132 DDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWL 191
Query: 210 -------------GYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQ 256
GY+ RY + + +D+V + +D+G+Y CIV E
Sbjct: 192 KNGKEFKPDHRIGGYKVRYATWSIIMDSV------------VPSDKGNYTCIVEN---EY 236
Query: 257 GNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWS 316
G+ + ++V +L+A +P N +VA G ++ C + + D +P + W
Sbjct: 237 GSINHTYQ--LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS----DPQPHIQW- 289
Query: 317 FSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV- 375
+ + GS++ D V ++ D L +R+VS E++G Y C
Sbjct: 290 ---LKHIEVNGSKI--GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAG 344
Query: 376 SLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVY 411
+ H+ +W V EA+ V + L + +Y
Sbjct: 345 NSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIY 380
>gi|105990522 fibroblast growth factor receptor 1 isoform 1
precursor [Homo sapiens]
Length = 822
Score = 49.7 bits (117), Expect = 1e-05
Identities = 74/336 (22%), Positives = 131/336 (38%), Gaps = 53/336 (15%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKV-LADSLHVGPSARPP 154
RT E+ +++ P+D G Y C T S + DT V ++D+L
Sbjct: 78 RTRITGEEVEVQDSVPADSGLYACVTSSPSGS------DTTYFSVNVSDALPSSEDDDDD 131
Query: 155 PSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARRSV-LALTHEGRFHPGL--- 209
S E E + +P T + + +H PA ++V G +P L
Sbjct: 132 DDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWL 191
Query: 210 -------------GYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQ 256
GY+ RY + + +D+V + +D+G+Y CIV E
Sbjct: 192 KNGKEFKPDHRIGGYKVRYATWSIIMDSV------------VPSDKGNYTCIVEN---EY 236
Query: 257 GNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWS 316
G+ + ++V +L+A +P N +VA G ++ C + + D +P + W
Sbjct: 237 GSINHTYQ--LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS----DPQPHIQW- 289
Query: 317 FSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV- 375
+ + GS++ D V ++ D L +R+VS E++G Y C
Sbjct: 290 ---LKHIEVNGSKI--GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAG 344
Query: 376 SLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVY 411
+ H+ +W V EA+ V + L + +Y
Sbjct: 345 NSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIY 380
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 48.1 bits (113), Expect = 3e-05
Identities = 59/255 (23%), Positives = 98/255 (38%), Gaps = 48/255 (18%)
Query: 74 WEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE 133
W +G Q+ + G + + L+I+N+ P D G Y+C A + G+
Sbjct: 2081 WVLGDGTQIRPSQFLHGNLFVFPNGT----LYIRNLAPKDSGRYEC----VAANLVGSAR 2132
Query: 134 DTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVHRGPAR 193
TVQ+ V + + + P +R G +L C +AS P +LW R P++
Sbjct: 2133 RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDC-SASGDPWP---RILW---RLPSK 2185
Query: 194 RSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI 253
R + AL S D R+ + L V D G Y C+ +
Sbjct: 2186 RMIDAL----------------FSFDSRIKVFANGT--LVVKSVTDKDAGDYLCVARNKV 2227
Query: 254 AEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEV 313
+ + V VV++P+ + + V G +L + C T PE+
Sbjct: 2228 GD--------DYVVLKVDVVMKPAKIEHKEENDHKVFYGGDLKVDCVAT----GLPNPEI 2275
Query: 314 TWSFSRMPDSTLPGS 328
+WS +PD +L S
Sbjct: 2276 SWS---LPDGSLVNS 2287
Score = 35.8 bits (81), Expect = 0.18
Identities = 36/145 (24%), Positives = 57/145 (39%), Gaps = 32/145 (22%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGE 163
L IK+++PSD G Y+C D D + +VL S P+ + ++ GE
Sbjct: 540 LRIKSMEPSDSGLYQCIAQVRDEM------DRMVYRVLVQSPSTQPAEKDTVTIGKNPGE 593
Query: 164 PFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLD 223
L C A + H L W + P RR + L ++ V +
Sbjct: 594 SVTLPCNALAIPEAH----LSWIL---PNRRIINDLA---------------NTSHVYML 631
Query: 224 TVGSDAYRLSVSRALSADQGSYRCI 248
G+ LS+ + +D G YRC+
Sbjct: 632 PNGT----LSIPKVQVSDSGYYRCV 652
>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 46.2 bits (108), Expect = 1e-04
Identities = 76/337 (22%), Positives = 134/337 (39%), Gaps = 57/337 (16%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKV-LADSLHVGPSARPP 154
RT E+ +++ P+D G Y C T S + DT V ++D+L PS+
Sbjct: 78 RTRITGEEVEVQDSVPADSGLYACVTSSPSGS------DTTYFSVNVSDAL---PSSEDD 128
Query: 155 PSLSLREGEPFELRCTAAS-ASPLHTHLALLWE-VHRGPARRSV-LALTHEGRFHPGL-- 209
E E T + +P T + + +H PA ++V G +P L
Sbjct: 129 DDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRW 188
Query: 210 --------------GYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE 255
GY+ RY + + +D+V + +D+G+Y CIV E
Sbjct: 189 LKNGKEFKPDHRIGGYKVRYATWSIIMDSV------------VPSDKGNYTCIVEN---E 233
Query: 256 QGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW 315
G+ + ++V +L+A +P N +VA G ++ C + + D +P + W
Sbjct: 234 YGSINHTYQ--LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS----DPQPHIQW 287
Query: 316 SFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV 375
+ + GS++ D V ++ D L +R+VS E++G Y C
Sbjct: 288 ----LKHIEVNGSKI--GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLA 341
Query: 376 -SLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVY 411
+ H+ +W V EA+ V + L + +Y
Sbjct: 342 GNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIY 378
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/247 (25%), Positives = 86/247 (34%), Gaps = 73/247 (29%)
Query: 88 QRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHV 147
+RG L T L + V P+D G Y C + G E ++ V VL + H
Sbjct: 2086 RRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENGS----GPKEASITVSVLHGT-HS 2140
Query: 148 GPSARP-----------PPSLSLREGEPFELRCTAASASPLHTHLALLWEVHRG--PARR 194
GPS P P S + EG+ +L C P H + W G PAR
Sbjct: 2141 GPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVV----PGQAHAQVTWHKRGGSLPARH 2196
Query: 195 SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIA 254
H +RL V AD G Y C V
Sbjct: 2197 QT-------------------HGSLLRLHQV------------TPADSGEYVCHVV---- 2221
Query: 255 EQGNWQEIQEKAVEVATVVIQPSVLRAAVP------KNVSVAEGKELDLTCNITTDRADD 308
G ++ + V I+ SV+ +P + +VAEG+ LDL+C + A
Sbjct: 2222 --GTSGPLEASVL----VTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVV----AGQ 2271
Query: 309 VRPEVTW 315
+VTW
Sbjct: 2272 AHAQVTW 2278
Score = 43.5 bits (101), Expect = 9e-04
Identities = 84/366 (22%), Positives = 128/366 (34%), Gaps = 82/366 (22%)
Query: 88 QRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHV 147
+RG L R L + V P+D G Y C T ++ + T++ V+ +
Sbjct: 2187 KRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGP--I 2244
Query: 148 GPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVHRG--PARRSVLALTHEGRF 205
P S ++ EG+ +L C A H + W G PAR V
Sbjct: 2245 PPVRIESSSSTVAEGQTLDLSCVVAG----QAHAQVTWYKRGGSLPARHQVR-------- 2292
Query: 206 HPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEK 265
GS RL + +A AD G Y C S + +
Sbjct: 2293 --------------------GS---RLYIFQASPADAGQYVCRASNGMEASITVTVTGTQ 2329
Query: 266 AVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTL 325
+A +R P + VAEG+ LDL C + +VTW +L
Sbjct: 2330 GANLAYPAGSTQPIRIE-PSSSQVAEGQTLDLNCVV----PGQSHAQVTW---HKRGGSL 2381
Query: 326 PGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRS 385
P V H +L L + S +SG Y C V + S
Sbjct: 2382 P-------------VRHQTHGSL---------LRLYQASPADSGEYVCRVLGSSVPLEAS 2419
Query: 386 WHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPT-ELACRVVDTKSGEANVRFT 444
E S +GVT P ++ ++S+V A+ T +L C V +G+A+ +
Sbjct: 2420 VLVTIEPAGSVPALGVT---PTVRIESSSSQV---AEGQTLDLNCLV----AGQAHAQ-- 2467
Query: 445 VSWYYR 450
V+W+ R
Sbjct: 2468 VTWHKR 2473
Score = 43.5 bits (101), Expect = 9e-04
Identities = 61/235 (25%), Positives = 85/235 (36%), Gaps = 50/235 (21%)
Query: 88 QRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHV 147
+RG L R L + V P+D G Y C + T + + T+Q + L+ S
Sbjct: 2472 KRGGSLPARHQVHGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR-LSGSHSQ 2530
Query: 148 G---PSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVHRG--PARRSVLALTHE 202
G P S SL G +L C AS +P HT + W G P+R +
Sbjct: 2531 GVAYPVRIESSSASLANGHTLDLNCLVASQAP-HT---ITWYKRGGSLPSRHQI------ 2580
Query: 203 GRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIA--EQGNWQ 260
VGS RL + + AD G Y C VS E
Sbjct: 2581 ----------------------VGS---RLRIPQVTPADSGEYVCHVSNGAGSRETSLIV 2615
Query: 261 EIQEKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW 315
IQ V P + ++ P +V EG+ LDL C + A + +TW
Sbjct: 2616 TIQGSGSSHVPSVSPPIRIESSSP---TVVEGQTLDLNCVV----ARQPQAIITW 2663
Score = 41.2 bits (95), Expect = 0.004
Identities = 78/326 (23%), Positives = 123/326 (37%), Gaps = 82/326 (25%)
Query: 86 RLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSL 145
RL G++ R + + L I+NVQ SD G Y C+ + A QG VQ + +L
Sbjct: 1808 RLHNGKLPTRAMDFNGI-LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQA---SGTL 1863
Query: 146 HVGPSARPPPSLSLREGEPFELRCTAASASPLHT---------HLALLWEVHRGPARRSV 196
+ PP L+++ G+ E RC +A+ SP T L ++H G R
Sbjct: 1864 SAPVVSIHPPQLTVQPGQLAEFRC-SATGSPTPTLEWTGGPGGQLPAKAQIHGGILRLPA 1922
Query: 197 LALTHEGRF----HPGLGYE----------------------QRYHSG-DVRL------- 222
+ T + ++ H G + + H+G VRL
Sbjct: 1923 VEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGV 1982
Query: 223 ------------------DTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQ-EIQ 263
+ +D L + +AD G Y C+ + + G Q IQ
Sbjct: 1983 PSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVAT---SPAGTAQARIQ 2039
Query: 264 EKAVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW---SFSRM 320
+ + P + ++ P SV EG+ LDL C + A +VTW S
Sbjct: 2040 VVVLSASDASPPPVKIESSSP---SVTEGQTLDLNCVV----AGSAHAQVTWYRRGGSLP 2092
Query: 321 PDSTLPGSRVLARLDRDSLVHSSPHV 346
P + + GSR+ RL + S S +V
Sbjct: 2093 PHTQVHGSRL--RLPQVSPADSGEYV 2116
Score = 40.4 bits (93), Expect = 0.007
Identities = 57/243 (23%), Positives = 87/243 (35%), Gaps = 61/243 (25%)
Query: 88 QRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHV 147
+RG L L + +V P+D G Y C + ++ + T++ + ++HV
Sbjct: 2762 KRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASG-SSAVHV 2820
Query: 148 -GPSARPP----PSLS-LREGEPFELRCTAASASPLHTHLALLWEVHRG--PARRSVLAL 199
P PP PS S + EG+ +L+C P H + W G PAR V
Sbjct: 2821 PAPGGAPPIRIEPSSSRVAEGQTLDLKCVV----PGQAHAQVTWHKRGGNLPARHQV--- 2873
Query: 200 THEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNW 259
H +RL+ V AD G Y C V+ G
Sbjct: 2874 ----------------HGPLLRLNQVS------------PADSGEYSCQVT---GSSGTL 2902
Query: 260 QEIQEKAVE-------VATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPE 312
+ +E A + QP + A+ + V EG+ LDL C + +
Sbjct: 2903 EASVLVTIEPSSPGPIPAPGLAQPIYIEAS---SSHVTEGQTLDLNCVV----PGQAHAQ 2955
Query: 313 VTW 315
VTW
Sbjct: 2956 VTW 2958
Score = 39.7 bits (91), Expect = 0.012
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 103 ELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREG 162
ELH +VQPSD G Y C+ + Q N + A S + + S S+R G
Sbjct: 1730 ELHFPSVQPSDAGVYICTCRNLH---QSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPG 1786
Query: 163 EPFELRCTAASASPLHTHLALLW-EVHRG 190
CTA S SP +T L+W +H G
Sbjct: 1787 ADVTFICTAKSKSPAYT---LVWTRLHNG 1812
Score = 39.7 bits (91), Expect = 0.012
Identities = 68/295 (23%), Positives = 102/295 (34%), Gaps = 73/295 (24%)
Query: 88 QRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHV 147
+RG L R L + P+D G Y C + ++ + T++ +L V
Sbjct: 2376 KRGGSLPVRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGV 2435
Query: 148 GPSARPPPSLS-LREGEPFELRCTAASASPLHTHLALLWEVHRG--PARRSVLALTHEGR 204
P+ R S S + EG+ +L C A H + W G PAR V
Sbjct: 2436 TPTVRIESSSSQVAEGQTLDLNCLVAG----QAHAQVTWHKRGGSLPARHQV-------- 2483
Query: 205 FHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIV--SEWIAEQGNWQEI 262
RL + + AD G Y C V S E I
Sbjct: 2484 -----------------------HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Query: 263 QEK-AVEVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMP 321
Q++ + + V P + ++ + S+A G LDL C + A +TW + R
Sbjct: 2521 QQRLSGSHSQGVAYPVRIESS---SASLANGHTLDLNCLV----ASQAPHTITW-YKR-- 2570
Query: 322 DSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVS 376
+LP R +V S L + V+ +SG Y CHVS
Sbjct: 2571 GGSLP--------SRHQIVGS--------------RLRIPQVTPADSGEYVCHVS 2603
Score = 37.0 bits (84), Expect = 0.080
Identities = 64/277 (23%), Positives = 95/277 (34%), Gaps = 82/277 (29%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSA----RPPPSLSL 159
L I + +PSD G Y C + T Q QV+V+ D+ + P A L++
Sbjct: 3170 LQISSAKPSDAGTYVCLAQNALGTAQ------KQVEVIVDTGAMAPGAPQVQAEEAELTV 3223
Query: 160 REGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGD 219
G LRC +A+ SP T + W R P L ++ R GD
Sbjct: 3224 EAGHTATLRC-SATGSPAPT---IHWSKLRSP-----------------LPWQHRL-EGD 3261
Query: 220 VRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVL 279
L + R D G Y C N A + ++
Sbjct: 3262 T-----------LIIPRVAQQDSGQYIC----------NATSPAGHAEATIILHVESPPY 3300
Query: 280 RAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSL 339
VP++ SV G+ + L C P +T+ +SR+ S+LPG
Sbjct: 3301 ATTVPEHASVQAGETVQLQC------LAHGTPPLTFQWSRV-GSSLPG------------ 3341
Query: 340 VHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVS 376
AR+ L + E+SG Y C V+
Sbjct: 3342 ----------RATARNELLHFERAAPEDSGRYRCRVT 3368
Score = 32.0 bits (71), Expect = 2.6
Identities = 24/103 (23%), Positives = 37/103 (35%), Gaps = 25/103 (24%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLS----- 158
L + V P+D G Y C + T++ + T++ P P P L+
Sbjct: 2878 LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPS--------SPGPIPAPGLAQPIYI 2929
Query: 159 ------LREGEPFELRCTAASASPLHTHLALLWEVHRG--PAR 193
+ EG+ +L C P H + W G PAR
Sbjct: 2930 EASSSHVTEGQTLDLNCVV----PGQAHAQVTWYKRGGSLPAR 2968
>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
[Homo sapiens]
Length = 731
Score = 44.7 bits (104), Expect = 4e-04
Identities = 47/203 (23%), Positives = 87/203 (42%), Gaps = 28/203 (13%)
Query: 210 GYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEV 269
GY+ RY + + +D+V + +D+G+Y CIV E G+ + ++V
Sbjct: 114 GYKVRYATWSIIMDSV------------VPSDKGNYTCIVEN---EYGSINHTYQ--LDV 156
Query: 270 ATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSR 329
+L+A +P N +VA G ++ C + + D +P + W + + GS+
Sbjct: 157 VERSPHRPILQAGLPANKTVALGSNVEFMCKVYS----DPQPHIQW----LKHIEVNGSK 208
Query: 330 VLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV-SLWAPGHNRSWHK 388
+ D V ++ D L +R+VS E++G Y C + H+ +W
Sbjct: 209 I--GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLT 266
Query: 389 VAEAVSSPAGVGVTWLEPDYQVY 411
V EA+ V + L + +Y
Sbjct: 267 VLEALEERPAVMTSPLYLEIIIY 289
>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 44.7 bits (104), Expect = 4e-04
Identities = 47/203 (23%), Positives = 87/203 (42%), Gaps = 28/203 (13%)
Query: 210 GYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEV 269
GY+ RY + + +D+V + +D+G+Y CIV E G+ + ++V
Sbjct: 116 GYKVRYATWSIIMDSV------------VPSDKGNYTCIVEN---EYGSINHTYQ--LDV 158
Query: 270 ATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSR 329
+L+A +P N +VA G ++ C + + D +P + W + + GS+
Sbjct: 159 VERSPHRPILQAGLPANKTVALGSNVEFMCKVYS----DPQPHIQW----LKHIEVNGSK 210
Query: 330 VLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV-SLWAPGHNRSWHK 388
+ D V ++ D L +R+VS E++G Y C + H+ +W
Sbjct: 211 I--GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLT 268
Query: 389 VAEAVSSPAGVGVTWLEPDYQVY 411
V EA+ V + L + +Y
Sbjct: 269 VLEALEERPAVMTSPLYLEIIIY 291
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 42.0 bits (97), Expect = 0.002
Identities = 63/274 (22%), Positives = 96/274 (35%), Gaps = 56/274 (20%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLRE-- 161
L I+ Q SD+G Y C + + TVQV P+ P + ++ +
Sbjct: 1897 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP---------PTFENPKTETVSQVA 1947
Query: 162 GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVR 221
G P L C S P T + W R P S +
Sbjct: 1948 GSPLVLTCDV-SGVPAPT---VTWLKDRMPVESSAV------------------------ 1979
Query: 222 LDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
V S RL +SR A G+Y C+ AE + V V++ P + +
Sbjct: 1980 -HGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEA--------RKDFVVAVLVAPRIRSS 2030
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVH 341
V + V EG+E+ L C + P+V W P G + LD SLV
Sbjct: 2031 GVAREHHVLEGQEVRLDC----EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVL 2086
Query: 342 SSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV 375
L DA +Y + + + E++ + +V
Sbjct: 2087 K----GLRASDAGAYTCVAHNPAGEDARLHTVNV 2116
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 15/115 (13%)
Query: 231 RLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQ-PSVLRAAVPKNVSV 289
RL + A +D+G Y C VS + +AV T+ +Q P + VS
Sbjct: 1896 RLEIQEAQVSDKGLYSCKVS----------NVAGEAVRTFTLTVQVPPTFENPKTETVSQ 1945
Query: 290 AEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP 344
G L LTC+++ A P VTW RMP + V++R R L P
Sbjct: 1946 VAGSPLVLTCDVSGVPA----PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP 1996
Score = 38.9 bits (89), Expect = 0.021
Identities = 62/275 (22%), Positives = 100/275 (36%), Gaps = 67/275 (24%)
Query: 99 NDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLS 158
N LH++ Q + G Y C + + +E +V V PP L
Sbjct: 1118 NQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV---------------PPEL- 1161
Query: 159 LREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSG 218
+ + +P TAA LH+ L LL E G ++ E PG E Y
Sbjct: 1162 IGDLDPLT-NITAA----LHSPLTLLCEA-MGIPPPAIRWFRGEEPVSPG---EDTY--- 1209
Query: 219 DVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV 278
+ + + L +++ D G Y C+ S E ++ V++ PS+
Sbjct: 1210 ------LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE--------VLVPPSI 1255
Query: 279 LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDS 338
+ + + V +G+ L CN+T +P++TW R LAR D
Sbjct: 1256 ENEDLEEVIKVLDGQTAHLMCNVT----GHPQPKLTW---------FKDGRPLARGDAH- 1301
Query: 339 LVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYC 373
H SP L L V + ++G+Y C
Sbjct: 1302 --HISPDGVL---------LQVLQANLSSAGHYSC 1325
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
++ GE LL ++ L ++ V D G Y C S + +++ TV + H
Sbjct: 2250 MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPH 2304
Query: 147 VGPSARPPPSLSLREGEPFELRCTA 171
+ S + P LSL G P EL C A
Sbjct: 2305 IEDSGQ-PTELSLTPGAPMELLCDA 2328
Score = 34.7 bits (78), Expect = 0.40
Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 50/203 (24%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSL-- 157
D L I+ Q SD G Y+C + V G+ E ++V +V P PPSL
Sbjct: 746 DGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRV-----NVPPRITLPPSLPG 796
Query: 158 SLREGEPFELRCTAASA-SPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
+ P L C A A SP L+W P + PGL Q +
Sbjct: 797 PVLVNTPVRLTCNATGAPSP-----TLMWLKDGNPVSPAGT---------PGL---QVFP 839
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
G V L+++ A ++D G Y C+ + E ++ V V + P
Sbjct: 840 GGRV-----------LTLASARASDSGRYSCVAVSAVGE--------DRQDVVLQVHMPP 880
Query: 277 SVLRAAVPKNVSVAEGKELDLTC 299
S+L + NVSV + + L C
Sbjct: 881 SILGEEL--NVSVVANESVALEC 901
Score = 33.5 bits (75), Expect = 0.89
Identities = 52/222 (23%), Positives = 76/222 (34%), Gaps = 45/222 (20%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSL 159
D L + D GHY C + + +Y V V + R +L++
Sbjct: 931 DKALLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFP-------LRESHTLTV 983
Query: 160 REGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGD 219
REG P L C E P + ++ +G+ PG G ++ S
Sbjct: 984 REGHPTSLSC----------------ECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAV 1025
Query: 220 VRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVL 279
RL L + +A A +G+Y C S + GN + + V V + P
Sbjct: 1026 GRL---------LYLGQAQLAQEGTYTCECSNVV---GNSSQDLQLEVHVPPQIAGP--- 1070
Query: 280 RAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMP 321
P VSV + L CN T P VTW P
Sbjct: 1071 -REPPTQVSVVQDGVATLECNAT----GKPPPTVTWERDGQP 1107
Score = 32.3 bits (72), Expect = 2.0
Identities = 60/243 (24%), Positives = 88/243 (36%), Gaps = 55/243 (22%)
Query: 97 TANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPS 156
T + EL +KN++ D G Y C+ + + T+ V + +L P
Sbjct: 2895 TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL--------PGD 2946
Query: 157 LSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
SLR G+ LRC AA SP + W V+ P V +G
Sbjct: 2947 RSLRLGDRLWLRC-AARGSPTP---RIGWTVNDRPVTEGV--SEQDG------------- 2987
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
GS R +VSR D G+Y C + + +AV V P
Sbjct: 2988 ---------GSTLQRAAVSR---EDSGTYVCWAENRVG--------RTQAVSFVHVKEAP 3027
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
VL+ + G + L C + R D V P++ W +P L GS + +L
Sbjct: 3028 -VLQGEAFSYLVEPVGGSIQLDCVV---RGDPV-PDIHWIKDGLP---LRGSHLRHQLQN 3079
Query: 337 DSL 339
SL
Sbjct: 3080 GSL 3082
Score = 30.8 bits (68), Expect = 5.8
Identities = 56/238 (23%), Positives = 82/238 (34%), Gaps = 62/238 (26%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPP-SLSLREG 162
L I+ V D+G Y C+ + + G + V +KVL V P+ P P + ++ E
Sbjct: 659 LQIEKVDLRDEGIYTCAATN----LAGESKREVALKVL-----VPPNIEPGPVNKAVLEN 709
Query: 163 EPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRL 222
L C A+ P P + + + + +
Sbjct: 710 ASVTLECLASGVPP------------------------------PDVSWFKGHQPVSSWM 739
Query: 223 D-TVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
TV D L + +A +D GSYRC+ S G+ + V V + P L
Sbjct: 740 GVTVSVDGRVLRIEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPG 796
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDS--------TLPGSRVL 331
V N V LTCN T + P + W P S PG RVL
Sbjct: 797 PVLVNTPVR------LTCNATGAPS----PTLMWLKDGNPVSPAGTPGLQVFPGGRVL 844
Score = 30.0 bits (66), Expect = 9.8
Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 17/108 (15%)
Query: 232 LSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE 291
L++ R D G Y+C+ E G A +V +V+Q + + P++++V
Sbjct: 3082 LTIHRTERDDAGRYQCLAEN---EMG-------VAKKVVILVLQSAPVFQVEPQDMTVRS 3131
Query: 292 GKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSL 339
G ++ L C T + P + W + P L SR L L SL
Sbjct: 3132 GDDVALRCQAT----GEPTPTIEWLQAGQP---LRASRRLRTLPDGSL 3172
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 42.0 bits (97), Expect = 0.002
Identities = 63/274 (22%), Positives = 96/274 (35%), Gaps = 56/274 (20%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLRE-- 161
L I+ Q SD+G Y C + + TVQV P+ P + ++ +
Sbjct: 3088 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP---------PTFENPKTETVSQVA 3138
Query: 162 GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVR 221
G P L C S P T + W R P S +
Sbjct: 3139 GSPLVLTCDV-SGVPAPT---VTWLKDRMPVESSAV------------------------ 3170
Query: 222 LDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
V S RL +SR A G+Y C+ AE + V V++ P + +
Sbjct: 3171 -HGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEA--------RKDFVVAVLVAPRIRSS 3221
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVH 341
V + V EG+E+ L C + P+V W P G + LD SLV
Sbjct: 3222 GVAREHHVLEGQEVRLDC----EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVL 3277
Query: 342 SSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV 375
L DA +Y + + + E++ + +V
Sbjct: 3278 K----GLRASDAGAYTCVAHNPAGEDARLHTVNV 3307
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 15/115 (13%)
Query: 231 RLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQ-PSVLRAAVPKNVSV 289
RL + A +D+G Y C VS + +AV T+ +Q P + VS
Sbjct: 3087 RLEIQEAQVSDKGLYSCKVS----------NVAGEAVRTFTLTVQVPPTFENPKTETVSQ 3136
Query: 290 AEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP 344
G L LTC+++ A P VTW RMP + V++R R L P
Sbjct: 3137 VAGSPLVLTCDVSGVPA----PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP 3187
Score = 38.9 bits (89), Expect = 0.021
Identities = 62/275 (22%), Positives = 100/275 (36%), Gaps = 67/275 (24%)
Query: 99 NDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLS 158
N LH++ Q + G Y C + + +E +V V PP L
Sbjct: 2309 NQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV---------------PPEL- 2352
Query: 159 LREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSG 218
+ + +P TAA LH+ L LL E G ++ E PG E Y
Sbjct: 2353 IGDLDPLT-NITAA----LHSPLTLLCEA-MGIPPPAIRWFRGEEPVSPG---EDTY--- 2400
Query: 219 DVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV 278
+ + + L +++ D G Y C+ S E ++ V++ PS+
Sbjct: 2401 ------LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE--------VLVPPSI 2446
Query: 279 LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDS 338
+ + + V +G+ L CN+T +P++TW R LAR D
Sbjct: 2447 ENEDLEEVIKVLDGQTAHLMCNVT----GHPQPKLTW---------FKDGRPLARGDAH- 2492
Query: 339 LVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYC 373
H SP L L V + ++G+Y C
Sbjct: 2493 --HISPDGVL---------LQVLQANLSSAGHYSC 2516
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
++ GE LL ++ L ++ V D G Y C S + +++ TV + H
Sbjct: 3441 MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPH 3495
Query: 147 VGPSARPPPSLSLREGEPFELRCTA 171
+ S + P LSL G P EL C A
Sbjct: 3496 IEDSGQ-PTELSLTPGAPMELLCDA 3519
Score = 35.4 bits (80), Expect = 0.23
Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 76/293 (25%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSL-- 157
D L I+ Q SD G Y+C + V G+ E ++V +V P PPSL
Sbjct: 1937 DGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRV-----NVPPRITLPPSLPG 1987
Query: 158 SLREGEPFELRCTAASA-SPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
+ P L C A A SP L+W P + PGL Q +
Sbjct: 1988 PVLVNTPVRLTCNATGAPSP-----TLMWLKDGNPVSPAGT---------PGL---QVFP 2030
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
G V L+++ A ++D G Y C+ + E ++ V V + P
Sbjct: 2031 GGRV-----------LTLASARASDSGRYSCVAVSAVGE--------DRQDVVLQVHMPP 2071
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
S+L + NVSV + + L C P ++W P PG
Sbjct: 2072 SILGEEL--NVSVVANESVALECQSHAMPP----PVLSWWKDGRPLEPRPG--------- 2116
Query: 337 DSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKV 389
VH S AL VD ++G+Y C +L GH+ + +
Sbjct: 2117 ---VHLSADKALLQVDRADVW---------DAGHYTCE-ALNQAGHSEKHYNL 2156
Score = 33.9 bits (76), Expect = 0.68
Identities = 59/275 (21%), Positives = 91/275 (33%), Gaps = 72/275 (26%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPS-ARPPPSLS 158
D+ L ++V P DQ Y C + VQ L + H P A P++
Sbjct: 843 DSGVLFFESVAPEDQAPYVCEARNVFGKVQAEAR-------LIVTGHAPPQIASSAPTVR 895
Query: 159 LREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSG 218
+ EG+P L C + PL P R + +GR P G
Sbjct: 896 VLEGQPVSLPCIVLAGRPL-------------PERHWL----KDGRPLPPGSRHSIRADG 938
Query: 219 DVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV 278
+ LD RAL G Y C+ + Q +V VV P
Sbjct: 939 SLHLD------------RALQEHAGRYSCVATNTAGSQHR---------DVELVVQVPPR 977
Query: 279 LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDS 338
+ +++ EG L C + A P +TW+ + ++
Sbjct: 978 IHPTATHHIT-NEGVPASLPCVASGVPA----PTITWT-----------------KETNA 1015
Query: 339 LVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYC 373
L PH +S + LL+ S +++G Y C
Sbjct: 1016 LTSRGPHYNVS----KEGTLLIAQPSAQDAGAYVC 1046
Score = 33.1 bits (74), Expect = 1.2
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 10/69 (14%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPS-LSLREG 162
L + VQ D GHY+C+ + + Y VQV P +P P L + G
Sbjct: 1084 LRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVP---------PQVQPGPRVLKVLVG 1134
Query: 163 EPFELRCTA 171
E +L C A
Sbjct: 1135 EALDLNCVA 1143
Score = 33.1 bits (74), Expect = 1.2
Identities = 52/222 (23%), Positives = 76/222 (34%), Gaps = 45/222 (20%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSL 159
D L + D GHY C + + +Y V V + R +L++
Sbjct: 2122 DKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFP-------LRESHTLTV 2174
Query: 160 REGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGD 219
REG P L C E P + ++ +G+ PG G ++ S
Sbjct: 2175 REGHPTSLSC----------------ECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAV 2216
Query: 220 VRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVL 279
RL L + +A A +G+Y C S + GN + + V V + P
Sbjct: 2217 GRL---------LYLGQAQLAQEGTYTCECSNVV---GNSSQDLQLEVHVPPQIAGP--- 2261
Query: 280 RAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMP 321
P VSV + L CN T P VTW P
Sbjct: 2262 -REPPTQVSVVQDGVATLECNAT----GKPPPTVTWERDGQP 2298
Score = 32.3 bits (72), Expect = 2.0
Identities = 60/243 (24%), Positives = 88/243 (36%), Gaps = 55/243 (22%)
Query: 97 TANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPS 156
T + EL +KN++ D G Y C+ + + T+ V + +L P
Sbjct: 4086 TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL--------PGD 4137
Query: 157 LSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
SLR G+ LRC AA SP + W V+ P V +G
Sbjct: 4138 RSLRLGDRLWLRC-AARGSPTP---RIGWTVNDRPVTEGV--SEQDG------------- 4178
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
GS R +VSR D G+Y C + + +AV V P
Sbjct: 4179 ---------GSTLQRAAVSR---EDSGTYVCWAENRVG--------RTQAVSFVHVKEAP 4218
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
VL+ + G + L C + R D V P++ W +P L GS + +L
Sbjct: 4219 -VLQGEAFSYLVEPVGGSIQLDCVV---RGDPV-PDIHWIKDGLP---LRGSHLRHQLQN 4270
Query: 337 DSL 339
SL
Sbjct: 4271 GSL 4273
Score = 30.8 bits (68), Expect = 5.8
Identities = 56/238 (23%), Positives = 82/238 (34%), Gaps = 62/238 (26%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPP-SLSLREG 162
L I+ V D+G Y C+ + + G + V +KVL V P+ P P + ++ E
Sbjct: 1850 LQIEKVDLRDEGIYTCAATN----LAGESKREVALKVL-----VPPNIEPGPVNKAVLEN 1900
Query: 163 EPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRL 222
L C A+ P P + + + + +
Sbjct: 1901 ASVTLECLASGVPP------------------------------PDVSWFKGHQPVSSWM 1930
Query: 223 D-TVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
TV D L + +A +D GSYRC+ S G+ + V V + P L
Sbjct: 1931 GVTVSVDGRVLRIEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPG 1987
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDS--------TLPGSRVL 331
V N V LTCN T + P + W P S PG RVL
Sbjct: 1988 PVLVNTPVR------LTCNATGAPS----PTLMWLKDGNPVSPAGTPGLQVFPGGRVL 2035
Score = 30.0 bits (66), Expect = 9.8
Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 17/108 (15%)
Query: 232 LSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE 291
L++ R D G Y+C+ E G A +V +V+Q + + P++++V
Sbjct: 4273 LTIHRTERDDAGRYQCLAEN---EMG-------VAKKVVILVLQSAPVFQVEPQDMTVRS 4322
Query: 292 GKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSL 339
G ++ L C T + P + W + P L SR L L SL
Sbjct: 4323 GDDVALRCQAT----GEPTPTIEWLQAGQP---LRASRRLRTLPDGSL 4363
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 42.0 bits (97), Expect = 0.002
Identities = 63/274 (22%), Positives = 96/274 (35%), Gaps = 56/274 (20%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLRE-- 161
L I+ Q SD+G Y C + + TVQV P+ P + ++ +
Sbjct: 1806 LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVP---------PTFENPKTETVSQVA 1856
Query: 162 GEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVR 221
G P L C S P T + W R P S +
Sbjct: 1857 GSPLVLTCDV-SGVPAPT---VTWLKDRMPVESSAV------------------------ 1888
Query: 222 LDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
V S RL +SR A G+Y C+ AE + V V++ P + +
Sbjct: 1889 -HGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEA--------RKDFVVAVLVAPRIRSS 1939
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVH 341
V + V EG+E+ L C + P+V W P G + LD SLV
Sbjct: 1940 GVAREHHVLEGQEVRLDC----EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVL 1995
Query: 342 SSPHVALSHVDARSYHLLVRDVSKENSGYYYCHV 375
L DA +Y + + + E++ + +V
Sbjct: 1996 K----GLRASDAGAYTCVAHNPAGEDARLHTVNV 2025
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/115 (29%), Positives = 48/115 (41%), Gaps = 15/115 (13%)
Query: 231 RLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQ-PSVLRAAVPKNVSV 289
RL + A +D+G Y C VS + +AV T+ +Q P + VS
Sbjct: 1805 RLEIQEAQVSDKGLYSCKVS----------NVAGEAVRTFTLTVQVPPTFENPKTETVSQ 1854
Query: 290 AEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP 344
G L LTC+++ A P VTW RMP + V++R R L P
Sbjct: 1855 VAGSPLVLTCDVSGVPA----PTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQP 1905
Score = 38.9 bits (89), Expect = 0.021
Identities = 62/275 (22%), Positives = 100/275 (36%), Gaps = 67/275 (24%)
Query: 99 NDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLS 158
N LH++ Q + G Y C + + +E +V V PP L
Sbjct: 1027 NQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLV---------------PPEL- 1070
Query: 159 LREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSG 218
+ + +P TAA LH+ L LL E G ++ E PG E Y
Sbjct: 1071 IGDLDPLT-NITAA----LHSPLTLLCEA-MGIPPPAIRWFRGEEPVSPG---EDTY--- 1118
Query: 219 DVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV 278
+ + + L +++ D G Y C+ S E ++ V++ PS+
Sbjct: 1119 ------LLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVE--------VLVPPSI 1164
Query: 279 LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDS 338
+ + + V +G+ L CN+T +P++TW R LAR D
Sbjct: 1165 ENEDLEEVIKVLDGQTAHLMCNVT----GHPQPKLTW---------FKDGRPLARGDAH- 1210
Query: 339 LVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYC 373
H SP L L V + ++G+Y C
Sbjct: 1211 --HISPDGVL---------LQVLQANLSSAGHYSC 1234
Score = 36.6 bits (83), Expect = 0.11
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 6/85 (7%)
Query: 87 LQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLH 146
++ GE LL ++ L ++ V D G Y C S + +++ TV + H
Sbjct: 2159 MKDGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVM-----EPPH 2213
Query: 147 VGPSARPPPSLSLREGEPFELRCTA 171
+ S + P LSL G P EL C A
Sbjct: 2214 IEDSGQ-PTELSLTPGAPMELLCDA 2237
Score = 35.4 bits (80), Expect = 0.23
Identities = 71/293 (24%), Positives = 105/293 (35%), Gaps = 76/293 (25%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSL-- 157
D L I+ Q SD G Y+C + V G+ E ++V +V P PPSL
Sbjct: 655 DGRVLRIEQAQLSDAGSYRC----VASNVAGSTELRYGLRV-----NVPPRITLPPSLPG 705
Query: 158 SLREGEPFELRCTAASA-SPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
+ P L C A A SP L+W P + PGL Q +
Sbjct: 706 PVLVNTPVRLTCNATGAPSP-----TLMWLKDGNPVSPAGT---------PGL---QVFP 748
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
G V L+++ A ++D G Y C+ + E ++ V V + P
Sbjct: 749 GGRV-----------LTLASARASDSGRYSCVAVSAVGE--------DRQDVVLQVHMPP 789
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
S+L + NVSV + + L C P ++W P PG
Sbjct: 790 SILGEEL--NVSVVANESVALECQSHAMPP----PVLSWWKDGRPLEPRPG--------- 834
Query: 337 DSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKV 389
VH S AL VD ++G+Y C +L GH+ + +
Sbjct: 835 ---VHLSADKALLQVDRADVW---------DAGHYTCE-ALNQAGHSEKHYNL 874
Score = 33.1 bits (74), Expect = 1.2
Identities = 52/222 (23%), Positives = 76/222 (34%), Gaps = 45/222 (20%)
Query: 100 DAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSL 159
D L + D GHY C + + +Y V V + R +L++
Sbjct: 840 DKALLQVDRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFP-------LRESHTLTV 892
Query: 160 REGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGD 219
REG P L C E P + ++ +G+ PG G ++ S
Sbjct: 893 REGHPTRLSC----------------ECRGVPFPK--ISWRKDGQPLPGEGAGLQHVSAV 934
Query: 220 VRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVL 279
RL L + +A A +G+Y C S + GN + + V V + P
Sbjct: 935 GRL---------LYLGQAQLAQEGTYTCECSNVV---GNSSQDLQLEVHVPPQIAGP--- 979
Query: 280 RAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMP 321
P VSV + L CN T P VTW P
Sbjct: 980 -REPPTQVSVVQDGVATLECNAT----GKPPPTVTWERDGQP 1016
Score = 32.7 bits (73), Expect = 1.5
Identities = 64/277 (23%), Positives = 97/277 (35%), Gaps = 74/277 (26%)
Query: 97 TANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPS 156
T + EL +KN++ D G Y C+ + + T+ V + +L P
Sbjct: 2804 TIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTL--------PGD 2855
Query: 157 LSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYH 216
SLR G+ LRC AA SP + W V+ P V +G
Sbjct: 2856 RSLRLGDRLWLRC-AARGSPTP---RIGWTVNDRPVTEGV--SEQDG------------- 2896
Query: 217 SGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQP 276
GS R +VSR D G+Y C + + +AV V P
Sbjct: 2897 ---------GSTLQRAAVSR---EDSGTYVCWAENRVG--------RTQAVSFVHVKEAP 2936
Query: 277 SVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDR 336
VL+ + G + L C + R D V P++ W +P L GS + +L
Sbjct: 2937 -VLQGEAFSYLVEPVGGSIQLDCVV---RGDPV-PDIHWIKDGLP---LRGSHLRHQLQN 2988
Query: 337 DSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYC 373
SL +R ++++G Y C
Sbjct: 2989 GSLT-------------------IRRTERDDAGRYQC 3006
Score = 30.8 bits (68), Expect = 5.8
Identities = 56/238 (23%), Positives = 82/238 (34%), Gaps = 62/238 (26%)
Query: 104 LHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPP-SLSLREG 162
L I+ V D+G Y C+ + + G + V +KVL V P+ P P + ++ E
Sbjct: 568 LQIEKVDLRDEGIYTCAATN----LAGESKREVALKVL-----VPPNIEPGPVNKAVLEN 618
Query: 163 EPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRL 222
L C A+ P P + + + + +
Sbjct: 619 ASVTLECLASGVPP------------------------------PDVSWFKGHQPVSSWM 648
Query: 223 D-TVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRA 281
TV D L + +A +D GSYRC+ S G+ + V V + P L
Sbjct: 649 GVTVSVDGRVLRIEQAQLSDAGSYRCVASN---VAGSTELRYGLRVNVPPRITLPPSLPG 705
Query: 282 AVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDS--------TLPGSRVL 331
V N V LTCN T + P + W P S PG RVL
Sbjct: 706 PVLVNTPVR------LTCNATGAPS----PTLMWLKDGNPVSPAGTPGLQVFPGGRVL 753
Score = 30.0 bits (66), Expect = 9.8
Identities = 28/108 (25%), Positives = 46/108 (42%), Gaps = 17/108 (15%)
Query: 232 LSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE 291
L++ R D G Y+C+ E G A +V +V+Q + + P++++V
Sbjct: 2991 LTIRRTERDDAGRYQCLAEN---EMG-------VAKKVVILVLQSAPVFQVEPQDMTVRS 3040
Query: 292 GKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSL 339
G ++ L C T + P + W + P L SR L L SL
Sbjct: 3041 GDDVALRCQAT----GEPTPTIEWLQAGQP---LRASRRLRTLPDGSL 3081
>gi|222144244 fibroblast growth factor receptor 2 isoform 9
precursor [Homo sapiens]
Length = 680
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 33/208 (15%)
Query: 208 GLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAV 267
G ++Q + G + V + + L + + +D+G+Y C+V E G+ +
Sbjct: 106 GKEFKQEHRIGGYK---VRNQHWSLIMESVVPSDKGNYTCVVEN---EYGSINHTYH--L 157
Query: 268 EVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW------SFSRMP 321
+V +L+A +P N S G +++ C + + D +P + W + S+
Sbjct: 158 DVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYS----DAQPHIQWIKHVEKNGSKYG 213
Query: 322 DSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPG 381
LP +VL HS + + + V L + +V++ ++G Y C VS +
Sbjct: 214 PDGLPYLKVLK--------HSGINSSNAEV------LALFNVTEADAGEYICKVSNYIGQ 259
Query: 382 HNRS-WHKVAEAVSSPAGVGVTWLEPDY 408
N+S W V +P PDY
Sbjct: 260 ANQSAWLTVLPKQQAPGREKEITASPDY 287
Score = 32.7 bits (73), Expect = 1.5
Identities = 45/175 (25%), Positives = 67/175 (38%), Gaps = 27/175 (15%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE-DTVQVKVLADSLHVGPSARPP 154
+ N L +++V PSD+G+Y C + ++ Y D V+ L G P
Sbjct: 119 KVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAG----LP 174
Query: 155 PSLSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHP-GLGY-E 212
+ S G E C S + H + W H + ++ P GL Y +
Sbjct: 175 ANASTVVGGDVEFVCKVYSDAQPH----IQWIKH---------VEKNGSKYGPDGLPYLK 221
Query: 213 QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI--AEQGNWQEIQEK 265
HSG S+A L++ AD G Y C VS +I A Q W + K
Sbjct: 222 VLKHSG-----INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK 271
>gi|222144231 fibroblast growth factor receptor 2 isoform 3
precursor [Homo sapiens]
Length = 769
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 33/208 (15%)
Query: 208 GLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAV 267
G ++Q + G + V + + L + + +D+G+Y C+V E G+ +
Sbjct: 195 GKEFKQEHRIGGYK---VRNQHWSLIMESVVPSDKGNYTCVVEN---EYGSINHTYH--L 246
Query: 268 EVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW------SFSRMP 321
+V +L+A +P N S G +++ C + + D +P + W + S+
Sbjct: 247 DVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYS----DAQPHIQWIKHVEKNGSKYG 302
Query: 322 DSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPG 381
LP +VL HS + + + V L + +V++ ++G Y C VS +
Sbjct: 303 PDGLPYLKVLK--------HSGINSSNAEV------LALFNVTEADAGEYICKVSNYIGQ 348
Query: 382 HNRS-WHKVAEAVSSPAGVGVTWLEPDY 408
N+S W V +P PDY
Sbjct: 349 ANQSAWLTVLPKQQAPGREKEITASPDY 376
Score = 32.7 bits (73), Expect = 1.5
Identities = 45/175 (25%), Positives = 67/175 (38%), Gaps = 27/175 (15%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE-DTVQVKVLADSLHVGPSARPP 154
+ N L +++V PSD+G+Y C + ++ Y D V+ L G P
Sbjct: 208 KVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAG----LP 263
Query: 155 PSLSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHP-GLGY-E 212
+ S G E C S + H + W H + ++ P GL Y +
Sbjct: 264 ANASTVVGGDVEFVCKVYSDAQPH----IQWIKH---------VEKNGSKYGPDGLPYLK 310
Query: 213 QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI--AEQGNWQEIQEK 265
HSG S+A L++ AD G Y C VS +I A Q W + K
Sbjct: 311 VLKHSG-----INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK 360
>gi|221316638 fibroblast growth factor receptor 2 isoform 2
precursor [Homo sapiens]
Length = 822
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/208 (22%), Positives = 86/208 (41%), Gaps = 33/208 (15%)
Query: 208 GLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAV 267
G ++Q + G + V + + L + + +D+G+Y C+V E G+ +
Sbjct: 195 GKEFKQEHRIGGYK---VRNQHWSLIMESVVPSDKGNYTCVVEN---EYGSINHTYH--L 246
Query: 268 EVATVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW------SFSRMP 321
+V +L+A +P N S G +++ C + + D +P + W + S+
Sbjct: 247 DVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYS----DAQPHIQWIKHVEKNGSKYG 302
Query: 322 DSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPG 381
LP +VL HS + + + V L + +V++ ++G Y C VS +
Sbjct: 303 PDGLPYLKVLK--------HSGINSSNAEV------LALFNVTEADAGEYICKVSNYIGQ 348
Query: 382 HNRS-WHKVAEAVSSPAGVGVTWLEPDY 408
N+S W V +P PDY
Sbjct: 349 ANQSAWLTVLPKQQAPGREKEITASPDY 376
Score = 32.7 bits (73), Expect = 1.5
Identities = 45/175 (25%), Positives = 67/175 (38%), Gaps = 27/175 (15%)
Query: 96 RTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYE-DTVQVKVLADSLHVGPSARPP 154
+ N L +++V PSD+G+Y C + ++ Y D V+ L G P
Sbjct: 208 KVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAG----LP 263
Query: 155 PSLSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHP-GLGY-E 212
+ S G E C S + H + W H + ++ P GL Y +
Sbjct: 264 ANASTVVGGDVEFVCKVYSDAQPH----IQWIKH---------VEKNGSKYGPDGLPYLK 310
Query: 213 QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI--AEQGNWQEIQEK 265
HSG S+A L++ AD G Y C VS +I A Q W + K
Sbjct: 311 VLKHSG-----INSSNAEVLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK 360
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 39.7 bits (91), Expect = 0.012
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 83 YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLA 142
YQ+ LQ G+ R D + IKNV SD G Y+C + Q EDTV ++VL
Sbjct: 75 YQQTLQ-GDFKNRAEMID-FNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLV 132
Query: 143 DSLHVGPSARPPPSLSLREGEPFELRCTAASASP 176
PS P S G ELRC +P
Sbjct: 133 --APAVPSCEVPS--SALSGTVVELRCQDKEGNP 162
Score = 37.7 bits (86), Expect = 0.047
Identities = 32/105 (30%), Positives = 49/105 (46%), Gaps = 10/105 (9%)
Query: 211 YEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVA 270
Y Q+ GD + D + + + +D G YRC VS +EQG Q ++E V +
Sbjct: 74 YYQQTLQGDFKNRAEMID-FNIRIKNVTRSDAGKYRCEVSA-PSEQG--QNLEEDTVTL- 128
Query: 271 TVVIQPSVLRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTW 315
V++ P+V VP S G ++L C D+ + PE TW
Sbjct: 129 EVLVAPAVPSCEVPS--SALSGTVVELRCQ---DKEGNPAPEYTW 168
Score = 35.0 bits (79), Expect = 0.31
Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 1/46 (2%)
Query: 481 QRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNN 526
Q+ GDF E D FN RI+ T D G Y C VSA ++Q N
Sbjct: 76 QQTLQGDFKNRAEMID-FNIRIKNVTRSDAGKYRCEVSAPSEQGQN 120
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 39.3 bits (90), Expect = 0.016
Identities = 41/145 (28%), Positives = 60/145 (41%), Gaps = 22/145 (15%)
Query: 232 LSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE 291
L + D YRC V + + +EI E +E+ TV ++P VPK V V
Sbjct: 145 LKIWNVTRRDSALYRCEV----VARNDRKEIDEIVIEL-TVQVKPVTPVCRVPKAVPV-- 197
Query: 292 GKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHV 351
GK L C + RP +W + +P T SR R S H+
Sbjct: 198 GKMATLHCQ---ESEGHPRPHYSWYRNDVPLPT--DSRANPRFRNSSF----------HL 242
Query: 352 DARSYHLLVRDVSKENSGYYYCHVS 376
++ + L+ V K++SG YYC S
Sbjct: 243 NSETGTLVFTAVHKDDSGQYYCIAS 267
>gi|148743776 V-set and transmembrane domain containing 2 [Homo
sapiens]
Length = 236
Score = 39.3 bits (90), Expect = 0.016
Identities = 30/102 (29%), Positives = 49/102 (48%), Gaps = 13/102 (12%)
Query: 284 PKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLP-----GSRVLARLDRDS 338
P+NV+ EG+ ++++C + A V E+ W F R P+ P G++V DRD
Sbjct: 33 PRNVTATEGQNVEMSCAFQSGSA-SVYLEIQWWFLRGPEDLDPGAEGAGAQVELLPDRDP 91
Query: 339 LVHSSPHVALSHVDAR----SYHLLVRDVSKENSGYYYCHVS 376
S +S V + S+ L + V K++ G Y C V+
Sbjct: 92 ---DSDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVT 130
Score = 31.6 bits (70), Expect = 3.4
Identities = 30/115 (26%), Positives = 53/115 (46%), Gaps = 12/115 (10%)
Query: 154 PPSLSLREGEPFELRCTAASASPLHTHLALLWEVHRGPARRSVLALTHEGRFHPGLGYEQ 213
P +++ EG+ E+ C S S +L + W RGP A + L ++
Sbjct: 33 PRNVTATEGQNVEMSCAFQSGSA-SVYLEIQWWFLRGPEDLDPGAEGAGAQVE--LLPDR 89
Query: 214 RYHSGDVRLDTV---GSD-AYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQE 264
S ++ TV G+D +++L +S+ D+G Y C V++ N+ E+QE
Sbjct: 90 DPDSDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTD-----ANYGELQE 139
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 38.9 bits (89), Expect = 0.021
Identities = 47/176 (26%), Positives = 72/176 (40%), Gaps = 32/176 (18%)
Query: 10 LLALLSLALCRGRVV--RVPTATLVRVV-GTELVIPCNVSDYDGPSEQNFDWSFSSLGSS 66
LL LL LA GR + T+ +V VV G + +PC G W+ G
Sbjct: 16 LLLLLLLASFTGRCPAGELETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWARVDAGEG 75
Query: 67 FVELASTW-EVGFPAQ-LYQERLQR---------GEILLRRTANDAVELHIKNVQPSDQG 115
ELA + G Y+ R+++ G +LLR N +D+G
Sbjct: 76 AQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLR------------NAVQADEG 123
Query: 116 HYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTA 171
Y+C + A G+++ ++++VL L PS P P+L +G CTA
Sbjct: 124 EYECRVSTFPA---GSFQARLRLRVLVPPL---PSLNPGPALEEGQGLTLAASCTA 173
>gi|156564390 carcinoembryonic antigen-related cell adhesion
molecule 20 4L [Homo sapiens]
Length = 503
Score = 38.1 bits (87), Expect = 0.036
Identities = 71/314 (22%), Positives = 117/314 (37%), Gaps = 82/314 (26%)
Query: 68 VELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDAT 127
V + W + ++ ER+Q + D L I VQ D G Y+C + DA
Sbjct: 95 VNITIHWVSNNLSVVFHERMQ--------LSKDGKILTILIVQREDSGTYQCE--ARDAL 144
Query: 128 VQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREG-EPFELRCTAASASPLHTHLALLWE 186
+ + P L ++ G +P E++ + AS + E
Sbjct: 145 LSQRSD--------------------PIFLDVKYGPDPVEIKLESGVAS------GEVVE 178
Query: 187 VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSAD-QGSY 245
V G S + E + HP Y LD++ S R A+S + +G Y
Sbjct: 179 VMEG----SSMTFLAETKSHPPCAYTW------FLLDSILSHTTRTFTIHAVSREHEGLY 228
Query: 246 RCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE-GKELDLTCNITTD 304
RC+VS + ++ + +E T+ P V VP ++++ E + +DLTC
Sbjct: 229 RCLVSNSATHLSSLGTLKVRVLETLTM---PQV----VPSSLNLVENARSVDLTCQTVNQ 281
Query: 305 RADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVS 364
+ V W S P LP S H+ LS A + L++ +
Sbjct: 282 SVN-----VQWFLSGQP--LLP----------------SEHLQLS---ADNRTLIIHGLQ 315
Query: 365 KENSGYYYCHVSLW 378
+ ++G Y C V W
Sbjct: 316 RNDTGPYACEVWNW 329
>gi|156564378 carcinoembryonic antigen-related cell adhesion
molecule 20 5L [Homo sapiens]
Length = 596
Score = 38.1 bits (87), Expect = 0.036
Identities = 71/314 (22%), Positives = 117/314 (37%), Gaps = 82/314 (26%)
Query: 68 VELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDAT 127
V + W + ++ ER+Q + D L I VQ D G Y+C + DA
Sbjct: 95 VNITIHWVSNNLSVVFHERMQ--------LSKDGKILTILIVQREDSGTYQCE--ARDAL 144
Query: 128 VQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREG-EPFELRCTAASASPLHTHLALLWE 186
+ + P L ++ G +P E++ + AS + E
Sbjct: 145 LSQRSD--------------------PIFLDVKYGPDPVEIKLESGVAS------GEVVE 178
Query: 187 VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSAD-QGSY 245
V G S + E + HP Y LD++ S R A+S + +G Y
Sbjct: 179 VMEG----SSMTFLAETKSHPPCAYTW------FLLDSILSHTTRTFTIHAVSREHEGLY 228
Query: 246 RCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE-GKELDLTCNITTD 304
RC+VS + ++ + +E T+ P V VP ++++ E + +DLTC
Sbjct: 229 RCLVSNSATHLSSLGTLKVRVLETLTM---PQV----VPSSLNLVENARSVDLTCQTVNQ 281
Query: 305 RADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVS 364
+ V W S P LP S H+ LS A + L++ +
Sbjct: 282 SVN-----VQWFLSGQP--LLP----------------SEHLQLS---ADNRTLIIHGLQ 315
Query: 365 KENSGYYYCHVSLW 378
+ ++G Y C V W
Sbjct: 316 RNDTGPYACEVWNW 329
>gi|156564393 carcinoembryonic antigen-related cell adhesion
molecule 20 5S [Homo sapiens]
Length = 584
Score = 38.1 bits (87), Expect = 0.036
Identities = 71/314 (22%), Positives = 117/314 (37%), Gaps = 82/314 (26%)
Query: 68 VELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDAT 127
V + W + ++ ER+Q + D L I VQ D G Y+C + DA
Sbjct: 95 VNITIHWVSNNLSVVFHERMQ--------LSKDGKILTILIVQREDSGTYQCE--ARDAL 144
Query: 128 VQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREG-EPFELRCTAASASPLHTHLALLWE 186
+ + P L ++ G +P E++ + AS + E
Sbjct: 145 LSQRSD--------------------PIFLDVKYGPDPVEIKLESGVAS------GEVVE 178
Query: 187 VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSAD-QGSY 245
V G S + E + HP Y LD++ S R A+S + +G Y
Sbjct: 179 VMEG----SSMTFLAETKSHPPCAYTW------FLLDSILSHTTRTFTIHAVSREHEGLY 228
Query: 246 RCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE-GKELDLTCNITTD 304
RC+VS + ++ + +E T+ P V VP ++++ E + +DLTC
Sbjct: 229 RCLVSNSATHLSSLGTLKVRVLETLTM---PQV----VPSSLNLVENARSVDLTCQTVNQ 281
Query: 305 RADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVS 364
+ V W S P LP S H+ LS A + L++ +
Sbjct: 282 SVN-----VQWFLSGQP--LLP----------------SEHLQLS---ADNRTLIIHGLQ 315
Query: 365 KENSGYYYCHVSLW 378
+ ++G Y C V W
Sbjct: 316 RNDTGPYACEVWNW 329
>gi|156564388 carcinoembryonic antigen-related cell adhesion
molecule 20 4S [Homo sapiens]
Length = 491
Score = 38.1 bits (87), Expect = 0.036
Identities = 71/314 (22%), Positives = 117/314 (37%), Gaps = 82/314 (26%)
Query: 68 VELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDAT 127
V + W + ++ ER+Q + D L I VQ D G Y+C + DA
Sbjct: 95 VNITIHWVSNNLSVVFHERMQ--------LSKDGKILTILIVQREDSGTYQCE--ARDAL 144
Query: 128 VQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREG-EPFELRCTAASASPLHTHLALLWE 186
+ + P L ++ G +P E++ + AS + E
Sbjct: 145 LSQRSD--------------------PIFLDVKYGPDPVEIKLESGVAS------GEVVE 178
Query: 187 VHRGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSAD-QGSY 245
V G S + E + HP Y LD++ S R A+S + +G Y
Sbjct: 179 VMEG----SSMTFLAETKSHPPCAYTW------FLLDSILSHTTRTFTIHAVSREHEGLY 228
Query: 246 RCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSVLRAAVPKNVSVAE-GKELDLTCNITTD 304
RC+VS + ++ + +E T+ P V VP ++++ E + +DLTC
Sbjct: 229 RCLVSNSATHLSSLGTLKVRVLETLTM---PQV----VPSSLNLVENARSVDLTCQTVNQ 281
Query: 305 RADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVS 364
+ V W S P LP S H+ LS A + L++ +
Sbjct: 282 SVN-----VQWFLSGQP--LLP----------------SEHLQLS---ADNRTLIIHGLQ 315
Query: 365 KENSGYYYCHVSLW 378
+ ++G Y C V W
Sbjct: 316 RNDTGPYACEVWNW 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,541,246
Number of Sequences: 37866
Number of extensions: 1603473
Number of successful extensions: 5693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 160
Number of HSP's that attempted gapping in prelim test: 4480
Number of HSP's gapped (non-prelim): 1172
length of query: 879
length of database: 18,247,518
effective HSP length: 111
effective length of query: 768
effective length of database: 14,044,392
effective search space: 10786093056
effective search space used: 10786093056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.