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Search of human proteins with 40786420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40786420 immunoglobulin-like domain containing receptor 2
[Homo sapiens]
(639 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40786420 immunoglobulin-like domain containing receptor 2 [Ho... 1320 0.0
gi|45545424 LISCH protein isoform 2 [Homo sapiens] 347 2e-95
gi|45505163 LISCH protein isoform 1 [Homo sapiens] 322 5e-88
gi|45593136 LISCH protein isoform 3 [Homo sapiens] 204 2e-52
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho... 188 1e-47
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 43 0.001
gi|167234419 thyroid hormone receptor associated protein 3 [Homo... 43 0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 41 0.003
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 41 0.003
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 41 0.004
gi|60097902 filaggrin [Homo sapiens] 40 0.005
gi|168229156 NFKB activating protein [Homo sapiens] 40 0.005
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 40 0.007
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens] 40 0.009
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 38 0.033
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 38 0.033
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 37 0.056
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 37 0.056
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 37 0.056
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 36 0.095
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 36 0.095
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 36 0.095
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 36 0.095
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 36 0.095
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 36 0.095
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 36 0.095
gi|153945755 zinc finger protein 608 [Homo sapiens] 36 0.12
gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isof... 35 0.16
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 35 0.16
gi|239756792 PREDICTED: hypothetical protein [Homo sapiens] 35 0.21
>gi|40786420 immunoglobulin-like domain containing receptor 2 [Homo
sapiens]
Length = 639
Score = 1320 bits (3416), Expect = 0.0
Identities = 639/639 (100%), Positives = 639/639 (100%)
Query: 1 MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKS 60
MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKS
Sbjct: 1 MDRVLLRWISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSHQPAVVQWKFKS 60
Query: 61 YCQDRMGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGR 120
YCQDRMGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGR
Sbjct: 61 YCQDRMGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGR 120
Query: 121 EITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFA 180
EITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFA
Sbjct: 121 EITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFA 180
Query: 181 VEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGK 240
VEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGK
Sbjct: 181 VEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGK 240
Query: 241 AAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRI 300
AAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRI
Sbjct: 241 AAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRI 300
Query: 301 QADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQ 360
QADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQ
Sbjct: 301 QADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQ 360
Query: 361 FPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFAT 420
FPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFAT
Sbjct: 361 FPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFAT 420
Query: 421 GVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQ 480
GVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQ
Sbjct: 421 GVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQ 480
Query: 481 RSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPE 540
RSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPE
Sbjct: 481 RSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPE 540
Query: 541 GASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELT 600
GASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELT
Sbjct: 541 GASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELT 600
Query: 601 RGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV 639
RGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV
Sbjct: 601 RGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMSLVV 639
>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
Length = 649
Score = 347 bits (890), Expect = 2e-95
Identities = 233/615 (37%), Positives = 314/615 (51%), Gaps = 83/615 (13%)
Query: 2 DRVLLRWISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFS-TSSHQPAVVQWKFK 59
D V+ W+ L W TA +QVTV + V +LFQP L C + TS+ +V WK+K
Sbjct: 70 DAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYK 129
Query: 60 SYCQDRMGESLGMSSTRAQ---SLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDF 116
S+C+DR+ ++ +S Q L+ N ++PY++C DS RTVRVVA+KQG+ VTLGD+
Sbjct: 130 SFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDY 189
Query: 117 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLL 176
Y+GR ITI +ADL + WGDSG+YYC + + DL+G NE EL+VLGRT +A+LL
Sbjct: 190 YQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELL 249
Query: 177 PSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALY 236
P F + +W+FV +V L FL F+L+GICWCQCCPH+CCCYVRCPCCPD CCCP+ALY
Sbjct: 250 PGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALY 309
Query: 237 EAGKAAKAG----YPPS-------VSGVPGPYSIPSVPL-----GGAP-----SSGMLMD 275
AGKAA +G Y PS P P IP P GG P SS
Sbjct: 310 AAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQ 369
Query: 276 KPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPAR--RMRGRYN 333
+ P L +DS+ S VR GYRIQA ++ DSM+VLYY+EKELA FDP+R GR
Sbjct: 370 GSYVPLLRDTDSSVAS-EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE 428
Query: 334 NTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEY 393
+SE++SLHE+D R S R D E W G S + RG
Sbjct: 429 RAMSEVTSLHEDDWRSRPS----RGPALTPIRDEE-----WG---GHSPRSPRGWDQEPA 476
Query: 394 NKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELA--AFADSYGQRPRRADGNSHEA 451
++ +R +PR++S ++D+L + A+S + P G S
Sbjct: 477 REQAGGGWRARRPRARS-------------VDALDDLTPPSTAESGSRSPTSNGGRSR-- 521
Query: 452 RGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAED--AH 509
+ SR+ Y D ++ RSR+P D R +R RP D +H
Sbjct: 522 ----AYMPPRSRSRDDLYDQDDSRDF----PRSRDPHYDDFR------SRERPPADPRSH 567
Query: 510 LPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWS 569
R + D Y G E R +G+ +R +YY +
Sbjct: 568 HHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSE--------ERRRPHKEEEEEAYYPPA 619
Query: 570 PPGTYKAGSSQDDQE 584
PP Y SQ +E
Sbjct: 620 PP-PYSETDSQASRE 633
>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
Length = 630
Score = 322 bits (826), Expect = 5e-88
Identities = 225/615 (36%), Positives = 303/615 (49%), Gaps = 102/615 (16%)
Query: 2 DRVLLRWISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFS-TSSHQPAVVQWKFK 59
D V+ W+ L W TA +QVTV + V +LFQP L C + TS+ +V WK+K
Sbjct: 70 DAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYK 129
Query: 60 SYCQDRMGESLGMSSTRAQ---SLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDF 116
S+C+DR+ ++ +S Q L+ N ++PY++C DS RTVRVVA+KQG+ VTLGD+
Sbjct: 130 SFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDY 189
Query: 117 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLL 176
Y+GR ITI +ADL + WGDSG+YYC + + DL+G NE EL+VL
Sbjct: 190 YQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL---------- 239
Query: 177 PSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALY 236
+W+FV +V L FL F+L+GICWCQCCPH+CCCYVRCPCCPD CCCP+ALY
Sbjct: 240 ---------DWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALY 290
Query: 237 EAGKAAKAG----YPPS-------VSGVPGPYSIPSVPL-----GGAP-----SSGMLMD 275
AGKAA +G Y PS P P IP P GG P SS
Sbjct: 291 AAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQ 350
Query: 276 KPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPAR--RMRGRYN 333
+ P L +DS+ S VR GYRIQA ++ DSM+VLYY+EKELA FDP+R GR
Sbjct: 351 GSYVPLLRDTDSSVAS-EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE 409
Query: 334 NTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEY 393
+SE++SLHE+D R S R D E W G S + RG
Sbjct: 410 RAMSEVTSLHEDDWRSRPS----RGPALTPIRDEE-----WG---GHSPRSPRGWDQEPA 457
Query: 394 NKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELA--AFADSYGQRPRRADGNSHEA 451
++ +R +PR++S ++D+L + A+S + P G S
Sbjct: 458 REQAGGGWRARRPRARS-------------VDALDDLTPPSTAESGSRSPTSNGGRSR-- 502
Query: 452 RGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAED--AH 509
+ SR+ Y D ++ RSR+P D R +R RP D +H
Sbjct: 503 ----AYMPPRSRSRDDLYDQDDSRDF----PRSRDPHYDDFR------SRERPPADPRSH 548
Query: 510 LPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWS 569
R + D Y G E R +G+ +R +YY +
Sbjct: 549 HHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSE--------ERRRPHKEEEEEAYYPPA 600
Query: 570 PPGTYKAGSSQDDQE 584
PP Y SQ +E
Sbjct: 601 PP-PYSETDSQASRE 614
>gi|45593136 LISCH protein isoform 3 [Homo sapiens]
Length = 581
Score = 204 bits (519), Expect = 2e-52
Identities = 187/601 (31%), Positives = 263/601 (43%), Gaps = 123/601 (20%)
Query: 2 DRVLLRWISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFS-TSSHQPAVVQWKFK 59
D V+ W+ L W TA +QVTV + V +LFQP L C + TS+ +V WK+K
Sbjct: 70 DAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYK 129
Query: 60 SYCQDRMGESLGMSSTRAQ---SLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDF 116
S+C+DR+ ++ +S Q L+ N ++PY++C DS RTVRVVA+KQG+ VTLGD+
Sbjct: 130 SFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDY 189
Query: 117 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVL-------GRT 169
Y+GR ITI +ADL + WGDSG+YYC + + DL+G NE EL+VL +
Sbjct: 190 YQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLVYAAGKAATS 249
Query: 170 GLLADLLPSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSC 229
G+ + PS + P + P
Sbjct: 250 GVPSIYAPSTYAHLSP----------------------------------AKTP------ 269
Query: 230 CCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTG 289
P A+ G A GYP G PG S GG S + P L +DS+
Sbjct: 270 -PPPAMIPMGPAYN-GYP---GGYPGDVD-RSSSAGGQGS--------YVPLLRDTDSSV 315
Query: 290 GSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPAR--RMRGRYNNTISELSSLHEEDS 347
S VR GYRIQA ++ DSM+VLYY+EKELA FDP+R GR +SE++SLHE+D
Sbjct: 316 AS-EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDW 374
Query: 348 NFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPR 407
R S R D E W G S + RG ++ +R +PR
Sbjct: 375 RSRPS----RGPALTPIRDEE-----WG---GHSPRSPRGWDQEPAREQAGGGWRARRPR 422
Query: 408 SKSEMLSRKNFATGVPAVSMDELA--AFADSYGQRPRRADGNSHEARGGSRFERSESRAH 465
++S ++D+L + A+S + P G S + SR+
Sbjct: 423 ARS-------------VDALDDLTPPSTAESGSRSPTSNGGRSR------AYMPPRSRSR 463
Query: 466 SGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAED--AHLPRLVSRTPGTAPK 523
Y D ++ RSR+P D R +R RP D +H R +
Sbjct: 464 DDLYDQDDSRDF----PRSRDPHYDDFR------SRERPPADPRSHHHRTRDPRDNGSRS 513
Query: 524 YDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQ 583
D Y G E R +G+ +R +YY +PP Y SQ +
Sbjct: 514 GDLPYDGRLLEEAVRKKGSE--------ERRRPHKEEEEEAYYPPAPP-PYSETDSQASR 564
Query: 584 E 584
E
Sbjct: 565 E 565
>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
sapiens]
Length = 502
Score = 188 bits (477), Expect = 1e-47
Identities = 117/345 (33%), Positives = 165/345 (47%), Gaps = 82/345 (23%)
Query: 8 WISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTSSH-QPAVVQWKFKSYCQDR 65
W+ L WL A L VTV ++ LF +L+C ++TS+ Q VV W+FKS+C+D
Sbjct: 10 WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69
Query: 66 MGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTV-TLGDFYRGREITI 124
+ + S A SL + DP DC D++R VR+VA ++G LG YR R+ITI
Sbjct: 70 IFDYYSASYQAALSLGQ-----DPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRKITI 124
Query: 125 VHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLLPSFAVEIM 184
+ ADL I ++MW D G+YYC I P D G + V+L+VL
Sbjct: 125 QNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL------------------ 166
Query: 185 PEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALYEAGKAAKA 244
W+ V ++LG L +L+G+CWCQCCP CCCY+RCPCCP CCCP+
Sbjct: 167 -HWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPE----------- 214
Query: 245 GYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADK 304
+ P S+P +P + + PP+A
Sbjct: 215 ------EDLSLPSSLPQMP---------MTQTTNQPPIANG------------------- 240
Query: 305 ERDSMKVLYYVEKELAQFDPAR----RMRGRYNNTISELSSLHEE 345
VL Y+EKEL + A+ ++GR+ + S LSSL E
Sbjct: 241 ------VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSE 279
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 42.7 bits (99), Expect = 0.001
Identities = 67/298 (22%), Positives = 106/298 (35%), Gaps = 26/298 (8%)
Query: 337 SELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKE 396
S LS H ++ S S+ SG +G G SGA G ++
Sbjct: 276 SRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSPP 335
Query: 397 DRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSR 456
D+ S + R K+ + A G + S + S G+ R A G R R
Sbjct: 336 DKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPS---SQGRGGRAAGGAGRRRRRRRR 392
Query: 457 FERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSR 516
RS S A + +R R P RG + S +R R + D+ R +
Sbjct: 393 RRRSRSSASAP------------RRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGR-GAP 439
Query: 517 TPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGP--RSASYYAWSPPGTY 574
PG P + + G + + RP A + +P + GP +S+S P ++
Sbjct: 440 GPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSW 499
Query: 575 KAGSSQDDQEDASDDALP------PYSELELTRGPSYRGRDLPYHSNSEKKRKKEPAK 626
+ S S + P P + L+R GR HS +E R + ++
Sbjct: 500 SSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGR--ARHSEAEATRARRRSR 555
>gi|167234419 thyroid hormone receptor associated protein 3 [Homo
sapiens]
Length = 955
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/257 (23%), Positives = 97/257 (37%), Gaps = 27/257 (10%)
Query: 385 SRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRA 444
SR P + R R+S +S S+ R + + S E + + ++
Sbjct: 127 SRSPKRRSPSPRSRSHSRNSD-KSSSDRSRRSSSSRSSSNHSRVESSKRKSAKEKKSSSK 185
Query: 445 DGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWA-------- 496
D +A G ++ + ++ + SG D+ + S S +P DA G
Sbjct: 186 DSRPSQAAGDNQGDEAKEQTFSGGTSQDT------KASESSKPWPDATYGTGSASRASAV 239
Query: 497 --FSPARRRPAEDAHLPRLVSRT----PGTAPKYDHSYLGSARERQARPEGAS--RGGSL 548
SP R PA + L +V R P PK +++ P GA G
Sbjct: 240 SELSPRERSPALKSPLQSVVVRRRSPRPSPVPKPSPPLSSTSQMGSTLPSGAGYQSGTHQ 299
Query: 549 ETPSKRSAQLGPRSASYYAWSPPGTYKA-GSSQDDQEDASDDALPPYSELELTRGPSYRG 607
S L P S SPP T GSSQ ++ AS A Y++ L + G
Sbjct: 300 GQFDHGSGSLSPSKKSPVGKSPPSTGSTYGSSQKEESAASGGA--AYTKRYLEEQKTENG 357
Query: 608 RDLPY-HSNSEKKRKKE 623
+D +N++K++ KE
Sbjct: 358 KDKEQKQTNTDKEKIKE 374
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 41.2 bits (95), Expect = 0.003
Identities = 83/335 (24%), Positives = 113/335 (33%), Gaps = 42/335 (12%)
Query: 337 SELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGA-------SRGPS 389
S SS +D R + RS P D P S + G S G SRG S
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHS-LSGSSPGMKDIPRTPSRGRS 1478
Query: 390 AMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPA-------VSMDELAAFADSYGQRPR 442
+ + E + + +PRS+S N P S+D+ GQR R
Sbjct: 1479 ECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSR 1538
Query: 443 RADGNSHEAR-GGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLT-DADRGWAFSPA 500
+ + S ERSES + D + R RSR + + D SP
Sbjct: 1539 SGSSQELDVKPSASPQERSESDSSP----DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594
Query: 501 RRRPAEDAHL---PRLVSRT--------------PGTAPKYDHSYLGSARERQARPEGAS 543
R R + PR R P P+ S S++ R PEG+S
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSG-SSSKGRGPSPEGSS 1653
Query: 544 RGGSL--ETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTR 601
S P R+A+ G RS+ + SS+ E L S +
Sbjct: 1654 STESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSR-SASS 1712
Query: 602 GPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMS 636
P R R P H S EPA+K+ R S
Sbjct: 1713 SPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747
Score = 38.5 bits (88), Expect = 0.019
Identities = 87/395 (22%), Positives = 136/395 (34%), Gaps = 56/395 (14%)
Query: 247 PPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGY-RIQADKE 305
P S S P S + SS KP P P + + + S + + R + DK
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKS 472
Query: 306 RDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQFPVSG 365
P+RRM GR + + + ++ + RS Q+ S
Sbjct: 473 HSHT--------------PSRRM-GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSR 517
Query: 366 DLESNPDYWSGVMGGSS-GASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPA 424
+ W G SR P +++ R++Q R +S R + PA
Sbjct: 518 SAQR----WGRSRSPQRRGRSRSPQRPGWSRS-----RNTQRRGRSRSARRGRSHSRSPA 568
Query: 425 VSMDELAAFADSYGQ---------RPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLE 475
+ G+ R R +R + R SR+ + +
Sbjct: 569 TRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTR 628
Query: 476 EYYGQRSRSREPLTDADRGWAFSPARR---RPAEDAHLPRLVSRTPGTAPKYDHSYLGSA 532
+RSRSR P + R + +PARR R A R SRTP G +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRS-------GRS 681
Query: 533 RERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQD-------DQED 585
R R G SR + RS L R S ++ +P ++GSS + Q
Sbjct: 682 RSRTPARRGRSRSRTPRRGRSRSRSLVRRGRS-HSRTPQRRGRSGSSSERKNKSRTSQRR 740
Query: 586 ASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKR 620
+ ++ P E++ +R S R R L + K R
Sbjct: 741 SRSNSSP---EMKKSRISSRRSRSLSSPRSKAKSR 772
Score = 35.4 bits (80), Expect = 0.16
Identities = 61/247 (24%), Positives = 83/247 (33%), Gaps = 38/247 (15%)
Query: 381 SSGASRGPSAMEYNKE---DRESFRHSQPRSK--SEMLSRKNFATGVPAVSMDELAAFAD 435
S SR S+ E K R S S PRSK S + R++ + P
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP--- 793
Query: 436 SYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGW 495
PRR+ S + + SR SR+ S + Q S P G
Sbjct: 794 -----PRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGT 848
Query: 496 ---------------AFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSA--RERQAR 538
+ +P RR E + P L SRTP HS GS+ R + +
Sbjct: 849 PPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR-----HSCSGSSPPRVKSST 903
Query: 539 PEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELE 598
P S S K A + PR S+ S P + S + S + P S +E
Sbjct: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS---VSPCSNVE 960
Query: 599 LTRGPSY 605
P Y
Sbjct: 961 SRLLPRY 967
Score = 30.8 bits (68), Expect = 4.0
Identities = 45/171 (26%), Positives = 64/171 (37%), Gaps = 14/171 (8%)
Query: 379 GGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGV-PAVSMDELAAFADSY 437
GGS SR P+ E R S R + RS++ SRK + PA + + +
Sbjct: 1816 GGSGYHSRSPARQE---SSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT 1872
Query: 438 GQRPRRADGNSHEARGGSR---FERSESRAHSGFYQDDSLEE---YYGQRSRSREPLTDA 491
+R R R SR R SR+ + + S +RSRSR P
Sbjct: 1873 HRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTR 1932
Query: 492 DRGWAFSPARRRPAEDAHLP----RLVSRTPGTAPKYDHSYLGSARERQAR 538
R + +P RR + P R SRTP + S R++R
Sbjct: 1933 RRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983
Score = 30.8 bits (68), Expect = 4.0
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 6/78 (7%)
Query: 480 QRSRSREPLTDADRGWAFSP------ARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSAR 533
+RSRSR PL R + SP +R R A R ++R+P + S S R
Sbjct: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDR 2087
Query: 534 ERQARPEGASRGGSLETP 551
R A P TP
Sbjct: 2088 SRSATPPATRNHSGSRTP 2105
Score = 29.6 bits (65), Expect = 8.9
Identities = 25/108 (23%), Positives = 41/108 (37%), Gaps = 6/108 (5%)
Query: 521 APKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQ 580
AP HS +G + ++ +RS+ S+S + S + + SS
Sbjct: 2498 APGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG 2557
Query: 581 DDQEDASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKRKKEPAKKT 628
D+ +LP E+ L R PS P + E R+ P + T
Sbjct: 2558 SSSSDSEGSSLPVQPEVALKRVPS------PTPAPKEAVREGRPPEPT 2599
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 41.2 bits (95), Expect = 0.003
Identities = 68/277 (24%), Positives = 99/277 (35%), Gaps = 40/277 (14%)
Query: 345 EDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHS 404
ED+ R+ Q RS G SN + SG + S S S + + R S
Sbjct: 1176 EDAQHRKPMDQKRSSSL---GSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGS 1232
Query: 405 QPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRA 464
+ R K++ L TG +D+L S R D SH +R S + +
Sbjct: 1233 RDREKTKSLE----ITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS 1288
Query: 465 HSGFYQD-DSLEE---YYGQRSRSREPLT--------DADRGWAFSPARRRPAE------ 506
SG + D L+E Y R R RE DAD+ W + R R E
Sbjct: 1289 RSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERE 1348
Query: 507 -------DAHLPRLVS------RTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSK 553
D RL+S R ++ S + S + +A+ EG LE+ S+
Sbjct: 1349 RDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEG-EHERDLESTSR 1407
Query: 554 RSAQLGPRSASYYAWSPPGTYKAGSSQDDQE-DASDD 589
S L S G + S+ + +A DD
Sbjct: 1408 DSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDD 1444
Score = 31.2 bits (69), Expect = 3.1
Identities = 33/150 (22%), Positives = 49/150 (32%), Gaps = 12/150 (8%)
Query: 487 PLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGG 546
PL D R + ++++ P + KY Y R + +G RG
Sbjct: 243 PLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGR 302
Query: 547 SLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRGPSYR 606
E +R + PRS S S Q +S P + T PSY+
Sbjct: 303 DFE--RQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQ 360
Query: 607 ----------GRDLPYHSNSEKKRKKEPAK 626
P HS S +RK+ P +
Sbjct: 361 RTLTPPLRRSASPYPSHSLSSPQRKQSPPR 390
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 67 GESLGMSSTRAQSLSKRN--LEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITI 124
G+S+ + T S S R ++WD L R + ++K G+ Y+ R ++I
Sbjct: 36 GKSVTLPCTYHTSTSSREGLIQWDKLLLTHTERVVIWPFSNKN---YIHGELYKNR-VSI 91
Query: 125 VH-----DADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVL 166
+ DA + I +L D+G Y C ++ DLEG + V LLVL
Sbjct: 92 SNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL 138
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 40.4 bits (93), Expect = 0.005
Identities = 83/347 (23%), Positives = 121/347 (34%), Gaps = 55/347 (15%)
Query: 291 SHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISEL-SSLH-----E 344
SH+ +G + + S K+ D +R R++ S SS H E
Sbjct: 1196 SHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQE 1255
Query: 345 EDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAME---------YNK 395
+ S R S HQ S D E + D + G +S G S + +++
Sbjct: 1256 QSSGSRTSRHQGSSVS--QDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQ 1313
Query: 396 EDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGS 455
EDR S HS S+ ++ AVS E A R + G H GS
Sbjct: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQA----------RSSPGERH----GS 1359
Query: 456 RFERS-ESRAHSGF--YQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPR 512
R ++S +S HSG Q S G R S +T+++ S + AH
Sbjct: 1360 RHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSE---GHSEDSDTQSVSAH--- 1413
Query: 513 LVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPG 572
G A + S+ SAR + G SR + S +S S + + P
Sbjct: 1414 ------GQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHE------QSESTHGQTAPS 1461
Query: 573 TYKAGSSQDDQEDASDDALPPYSELELTR---GPSYRGRDLPYHSNS 616
T S+ +Q S + R G S GR YH S
Sbjct: 1462 TGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQS 1508
Score = 38.1 bits (87), Expect = 0.025
Identities = 79/343 (23%), Positives = 120/343 (34%), Gaps = 46/343 (13%)
Query: 291 SHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFR 350
SH+ +G + + S E D R R++ S+ S
Sbjct: 547 SHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQG 606
Query: 351 QSF--HQMRSKQFPVSGDLES-----NPDYWSGVM-----GGSSGASR-GPSAMEYNKED 397
QS R++ VS D +S + + WSG G + SR G + ED
Sbjct: 607 QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHED 666
Query: 398 RESFRHSQPRS-KSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSR 456
R HS S KS +N ++G A S ++ R + G H +R +
Sbjct: 667 RAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQA-----------RSSAGERHGSRHQLQ 715
Query: 457 FERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSR 516
S + +G Q S G R S TD++ +ED+ +
Sbjct: 716 SADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSE----------GHSEDSDTQSVSGH 765
Query: 517 TPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGT-YK 575
G A + S+ SAR+R E + R GS Q S S + W+ P T +
Sbjct: 766 --GQAGHHQQSHQESARDRSG--ERSRRSGSFLYQVSTHKQ----SESSHGWTGPSTGVR 817
Query: 576 AGSSQDDQEDASDDALPPYSE--LELTRGPSYRGRDLPYHSNS 616
GS + D S + + + G S RGR +H S
Sbjct: 818 QGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQS 860
Score = 35.0 bits (79), Expect = 0.21
Identities = 61/247 (24%), Positives = 90/247 (36%), Gaps = 32/247 (12%)
Query: 380 GSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQ 439
G SG+ ++ R+ RHS SR + A+ +S A S G
Sbjct: 885 GQSGSRSASRTTRNEEQSRDGSRHSG--------SRHHEASSHADISRHSQAGQGQSEGS 936
Query: 440 RPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRS-REPLTDADRGWAFS 498
R R G+S + S+S HS +DS E + G SR+ R + R +
Sbjct: 937 RTSRRQGSSVS-------QDSDSEGHS----EDS-ERWSGSASRNHRGSAQEQSRHGSRH 984
Query: 499 PARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSA--RERQARPEGASRGGSLETPSKRSA 556
P H S P + S G A QAR R GS S S+
Sbjct: 985 PRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSS 1044
Query: 557 QLG--PRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRGPSYRGRDLPYHS 614
+ PR + A G + + SQ ASD +SE T+ S G+D P+
Sbjct: 1045 RHSGIPRRQASSAVRDSGHWGSSGSQ-----ASDS--EGHSEESDTQSVSGHGQDGPHQQ 1097
Query: 615 NSEKKRK 621
+ ++ +
Sbjct: 1098 SHQESAR 1104
Score = 33.9 bits (76), Expect = 0.47
Identities = 58/251 (23%), Positives = 85/251 (33%), Gaps = 27/251 (10%)
Query: 399 ESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFE 458
+S RHSQ + SR + G + +D + A N H G SR +
Sbjct: 1245 DSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHH---GSSREQ 1301
Query: 459 RSESRAHSGFYQDDSLEEYY---GQRSRSREPLTDADRGWAFS---PARRRPAEDAHLPR 512
+ H GF+Q+D + R + G A S AR P E R
Sbjct: 1302 SRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE-----R 1356
Query: 513 LVSRTPGTAPKYDHSYLGSARERQARPEGASRG--GSLETPSK-RSAQLGPRSASYYAWS 569
SR +A HS +G + A + RG GS T S+ S +S S + +
Sbjct: 1357 HGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQA 1416
Query: 570 PPGTYKAGSSQDDQEDASDD-------ALPPYSELELTRG---PSYRGRDLPYHSNSEKK 619
P S Q S + + + E T G PS GR H +
Sbjct: 1417 GPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNS 1476
Query: 620 RKKEPAKKTND 630
+ ++ D
Sbjct: 1477 SRHSASQDGQD 1487
Score = 32.0 bits (71), Expect = 1.8
Identities = 83/391 (21%), Positives = 141/391 (36%), Gaps = 63/391 (16%)
Query: 239 GKAAKAGYPPSV-SGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKG 297
G+ G+P S G G Y SV G SG H P SD++ G R
Sbjct: 1485 GQDTIRGHPGSSRGGRQGSYHEQSVDRSG--HSGY--HHSHTTPQGRSDASHGQSGPRSA 1540
Query: 298 YRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMR 357
R ++E+ + + +P+ R ++ + + S + S + S
Sbjct: 1541 SRQTRNEEQSGDGSRHSGSRH---HEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD 1597
Query: 358 SKQFPVSGDLE-----SNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEM 412
S D E ++ +++ S SR P + ++EDR S HS S+
Sbjct: 1598 RDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRS---HQEDRASHGHSAESSRQSG 1654
Query: 413 LSRKNFATGVPAVSMDELAAFA--DSYGQRPRRADGNSHEA----------------RGG 454
++G A S E A + + +G R +++ +S ++ RG
Sbjct: 1655 TRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGS 1714
Query: 455 SRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRG-----------WAFSPARRR 503
S + S+S HS S+ +GQ ++ ++ RG + + +
Sbjct: 1715 SGSQASDSEGHSEESDTQSVSA-HGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHE 1773
Query: 504 PAEDAHLPRLVSRT-PGTAPKYDHSYLGSARERQARP---EGASRGGSLETPSKRSAQLG 559
+E AH RT P T + +R QAR AS+ G + G
Sbjct: 1774 QSESAH-----GRTGPSTGGRQ------RSRHEQARDSSRHSASQEGQDTIRGHPGSSRG 1822
Query: 560 PRSASYYAWSPPGTYKAGS--SQDDQEDASD 588
R S+Y S + +GS S ++ SD
Sbjct: 1823 GRQGSHYEQSVDSSGHSGSHHSHTTSQERSD 1853
Score = 31.2 bits (69), Expect = 3.1
Identities = 62/273 (22%), Positives = 102/273 (37%), Gaps = 50/273 (18%)
Query: 291 SHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYN--NTISELSSLHEEDSN 348
SH+ +G + + S E D +R R++ +T +++S +
Sbjct: 3141 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQG 3200
Query: 349 FRQSFHQMRSKQFPVSGDLES-----NPDYWSG---------VMGGSSGASRGPSAMEYN 394
+ + R + VS D +S + + WSG V S SR P + +
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRS---H 3257
Query: 395 KEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGG 454
EDR HS RS+ ++G A S E A R + G H G
Sbjct: 3258 HEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQA----------RSSPGERH----G 3303
Query: 455 SRFERS-ESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRL 513
SR ++S +S HSG R ++ + D+ R W S ++ +E H
Sbjct: 3304 SRHQQSADSSRHSGI-----------PRGQASSAVRDS-RHWGSSGSQASDSE-GHSEES 3350
Query: 514 VSRT---PGTAPKYDHSYLGSARERQARPEGAS 543
+++ G A + S+ SAR+R G S
Sbjct: 3351 DTQSVSGHGQAGPHQQSHQESARDRSGGRSGRS 3383
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 40.4 bits (93), Expect = 0.005
Identities = 69/294 (23%), Positives = 106/294 (36%), Gaps = 46/294 (15%)
Query: 362 PVSGDLESNPDYWSGVMGG---SSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNF 418
PVSG +PD + GG SS S PS + R S HS RS R
Sbjct: 3 PVSGS--RSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSGD----RNGL 56
Query: 419 ATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQ-------- 470
+ +S + SY R R A G F + S + G Y
Sbjct: 57 THQLGGLSQ---GSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKP 113
Query: 471 -----DDSLEEYYGQRSRS-REPLTD--ADRGWAFSPARRRPAEDAHLPRLVSRTPGTAP 522
D EE Q+ S RE + + A W SP P D H P P
Sbjct: 114 WPSLLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTP-----VEDEEP 168
Query: 523 KYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDD 582
K + ++ E + + S+ S + K+S++ R Y + + S D
Sbjct: 169 KKSTTSASTSEEEKKKKSSRSKERSKKRRKKKSSK---RKHKKY------SEDSDSDSDS 219
Query: 583 QEDASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKRKKEPAKKTNDFPTRMS 636
+ D+SD+ ++ + + R Y +KKR K+ K+++D ++ S
Sbjct: 220 ETDSSDEDNKRRAKKAKKKEKKKKHRSKKY----KKKRSKKSRKESSDSSSKES 269
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
sapiens]
Length = 1792
Score = 40.0 bits (92), Expect = 0.007
Identities = 67/284 (23%), Positives = 99/284 (34%), Gaps = 55/284 (19%)
Query: 248 PSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDST----GGSHSVRKGYRIQAD 303
P GVP P P P G P +G + P PP + ST G +
Sbjct: 573 PLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQ 632
Query: 304 KERDSMKVLYYVEKELAQFDPARRMRGRYNNTIS-ELSSLHEEDSNFRQSFHQMRSKQFP 362
S + Y ++ L + + + + N + EL + R+SF + +S
Sbjct: 633 APPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPY-- 690
Query: 363 VSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGV 422
SG+S S+ Y+K R RS+S S
Sbjct: 691 -------------------SGSSYSRSSYTYSKS-----RSGSTRSRSYSRS-------- 718
Query: 423 PAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQ-R 481
F+ S+ + R+ RG SR RS SR+H G+++ S Y +
Sbjct: 719 ----------FSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSH-GYHRSRSRSPPYRRYH 767
Query: 482 SRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKYD 525
SRSR P A RG SP +R + +R P YD
Sbjct: 768 SRSRSP--QAFRGQ--SPNKRNVPQGETEREYFNRYREVPPPYD 807
>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
Length = 951
Score = 39.7 bits (91), Expect = 0.009
Identities = 40/139 (28%), Positives = 55/139 (39%), Gaps = 14/139 (10%)
Query: 460 SESRAHSGFYQDDSLEEYYG----QRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVS 515
S+SR+ S SL Y RSRSR P R A SP RRR VS
Sbjct: 778 SKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSP-----RRRAHSPERRREERSVPTAYRVS 832
Query: 516 RTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSA-----SYYAWSP 570
R+PG + K S ++++ R ++ + S Q PR A S ++ S
Sbjct: 833 RSPGASRKRTRSRSPHEKKKKRRSRSRTKSKARSQSVSPSKQAAPRPAAPAAHSAHSASV 892
Query: 571 PGTYKAGSSQDDQEDASDD 589
GSSQ+ S +
Sbjct: 893 SPVESRGSSQERSRGVSQE 911
Score = 29.6 bits (65), Expect = 8.9
Identities = 28/111 (25%), Positives = 47/111 (42%), Gaps = 15/111 (13%)
Query: 523 KYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDD 582
K + +ARE+ A+ S+ L+ KR A L ++ +P +AG ++
Sbjct: 654 KLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLK----NPLPEAEAGKIEES 709
Query: 583 Q---EDASDDALP--------PYSELELTRGPSYRGRDLPYHSNSEKKRKK 622
E++S P P E++ PS + +D P EKK+KK
Sbjct: 710 PFSVEESSTTPCPLLTGGRPLPTLEVKPPDRPSSKSKDPPREEEKEKKKKK 760
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 37.7 bits (86), Expect = 0.033
Identities = 77/341 (22%), Positives = 110/341 (32%), Gaps = 56/341 (16%)
Query: 239 GKAAKAGYPPSVSGVPGPYSIPSVPLGGAPS-SGMLMDKPHPPPLAPSDSTGGS----HS 293
G++++ PS + P IPS PS S K + + PS S S
Sbjct: 205 GRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSS 264
Query: 294 VRKGYRIQADKERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSF 353
K Y + + R + P R G T S + S H N ++
Sbjct: 265 RVKSYNQASTRSRP--------QSHSQSRSPRRSRSGSQKRTHSRVRS-HSWKRNHSRAR 315
Query: 354 HQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEML 413
+ R G + + G S R + +++ + HS RS S+
Sbjct: 316 SRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKER 375
Query: 414 SRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDS 473
+ ++ PR+ G S G +R SR+ S D
Sbjct: 376 DHRGSSS--------------------PRKESGRSQS--GSPNKQRDHSRSRSPNKARD- 412
Query: 474 LEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLP-----RLVSRTPGTAPKYDHSY 528
RSRSR P DR + SP + R + P R SR+P A DHS
Sbjct: 413 -------RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKA--RDHSR 463
Query: 529 LGSA-----RERQARPEGASRGGSLETPSKRSAQLGPRSAS 564
S R R P L +PSK RS S
Sbjct: 464 SRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS 504
Score = 37.4 bits (85), Expect = 0.043
Identities = 54/252 (21%), Positives = 100/252 (39%), Gaps = 29/252 (11%)
Query: 385 SRGPS-AMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRR 443
SR P+ A ++++ + + RS+S R + G P+ D + + S ++ R+
Sbjct: 452 SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQ 511
Query: 444 ADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRR 503
+ +S E R RS S+ QR +SR P + DR + SP+ R
Sbjct: 512 SRSSSKER--DHRRSRSPSKER--------------QRRQSRSPNKERDRSQSRSPSEER 555
Query: 504 PAEDAHLP-RLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRS 562
+ P + R +P + S + R SR +P+K+S PR+
Sbjct: 556 EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSR-----SPNKQSGYSRPRA 610
Query: 563 AS-YYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKRK 621
+S A S T + +S ++ P S+ + R P ++ S +
Sbjct: 611 SSKEKAHSRSRTPSKEGNHSQSRTSSKESDP--SQSTVPRSPDWKRSPT---RTSSLSQN 665
Query: 622 KEPAKKTNDFPT 633
+ P+K ++ P+
Sbjct: 666 RTPSKTSSHSPS 677
Score = 37.0 bits (84), Expect = 0.056
Identities = 53/221 (23%), Positives = 82/221 (37%), Gaps = 12/221 (5%)
Query: 385 SRGPSAMEYNKEDRESFRH-SQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRR 443
SR PS ++ R S + RS+S R+ + P D + + S + R+
Sbjct: 500 SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQ 559
Query: 444 ADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRR 503
+ S E R RS S+ S EE SRSR P ++ +S R
Sbjct: 560 SRSPSKER--DRRRWRSPSKERERRQSRSSSEER--DHSRSRSP----NKQSGYSRPRAS 611
Query: 504 PAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSA 563
E AH SRTP + S S ++ +P++ S+ R+
Sbjct: 612 SKEKAHSR---SRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
Query: 564 SYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRGPS 604
S + P T+ +G Q+D+ DA + L R S
Sbjct: 669 SKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSS 709
Score = 32.3 bits (72), Expect = 1.4
Identities = 50/202 (24%), Positives = 75/202 (37%), Gaps = 20/202 (9%)
Query: 440 RPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSP 499
RP +AR SR + + D + G SR R P R SP
Sbjct: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSP 136
Query: 500 ARRRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLG 559
+R A P + RT G P S + + +Q G S G T ++ +
Sbjct: 137 SR------ASTPGRI-RTHGARPGMA-SRVRTPTSQQKGSRGKSYGRP-RTSNRERSDSQ 187
Query: 560 PRSASYYAWSPPGTYKAGSSQDDQEDASDDALPPYSELELTRG-PSYRGRDLPYHSNSEK 618
PR+ S ++ PPG G S + P ++ + G PS D P S+S K
Sbjct: 188 PRNLSKKSYRPPGGSGIGRSSELA------VTPSTAKCQTPTGIPSKEKSDNPSPSSSRK 241
Query: 619 KRKKE----PAKKTNDFPTRMS 636
+ P+++ + PT MS
Sbjct: 242 VKSYGQMIIPSREKSYSPTEMS 263
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 37.7 bits (86), Expect = 0.033
Identities = 38/164 (23%), Positives = 63/164 (38%), Gaps = 40/164 (24%)
Query: 8 WISLFWLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFSTS--SHQPAVVQWKFKSYCQDR 65
++ L L V +QVT+PD + L C ++T+ S + +QW F
Sbjct: 9 FLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSF------- 61
Query: 66 MGESLGMSSTRAQSLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDFYRGREITIV 125
K+ +E + + S+ G V +G F IT
Sbjct: 62 --------------FHKKEME------------PISIYFSQGGQAVAIGQFKD--RITGS 93
Query: 126 HD---ADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVL 166
+D A + I + DSG+Y C + P D G+N+ + + VL
Sbjct: 94 NDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVL 137
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 37.0 bits (84), Expect = 0.056
Identities = 35/148 (23%), Positives = 57/148 (38%), Gaps = 3/148 (2%)
Query: 339 LSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDR 398
L + EEDSN ++S + RSK S S S SR S+ +
Sbjct: 185 LDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSS 244
Query: 399 ESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRRADGNSHEARGGSRFE 458
R SKS SR + + P + + S +R R+ + + G +
Sbjct: 245 SRERSRSRGSKSRSSSRSHRGSSSP---RKRSYSSSSSSPERNRKRSRSRSSSSGDRKKR 301
Query: 459 RSESRAHSGFYQDDSLEEYYGQRSRSRE 486
R+ SR+ ++ S + G RS S++
Sbjct: 302 RTRSRSPERRHRSSSGSSHSGSRSSSKK 329
Score = 30.4 bits (67), Expect = 5.2
Identities = 49/243 (20%), Positives = 86/243 (35%), Gaps = 12/243 (4%)
Query: 344 EEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRH 403
EE + + F++ + ++ + + D + G + GP+++ ED+ES
Sbjct: 97 EERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKES--E 154
Query: 404 SQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYG-QRPRRADGNSHEARGGSRFERSES 462
+ + E LS+ DE A Y D N ++ SR + S
Sbjct: 155 GEEEDEDEDLSKYKLDE-----DEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSS 209
Query: 463 RAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAP 522
+ S RSRSR + R + S R R S ++P
Sbjct: 210 HSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSP 269
Query: 523 -KYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQD 581
K +S S+ ER + SR S + ++ + RS S G+ +GS
Sbjct: 270 RKRSYSSSSSSPERNRK---RSRSRSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSS 326
Query: 582 DQE 584
++
Sbjct: 327 SKK 329
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 37.0 bits (84), Expect = 0.056
Identities = 62/287 (21%), Positives = 109/287 (37%), Gaps = 35/287 (12%)
Query: 354 HQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEML 413
H+ SK+ + + E + Y + V + SR S + ++R+S +H++ K M
Sbjct: 429 HKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDS-KHNRNEEK-RMR 486
Query: 414 SRKNFATGVPAVSMDELAAFADSYG---------QRPRRADGNSHEARGGSRFERSESRA 464
SR G ++ E +DS G ++ ++ + S+E S+ + + RA
Sbjct: 487 SRSK---GRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNE-HDHSKSKEKDRRA 542
Query: 465 HSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAPKY 524
S + D + + SR+RE DR RR H R + +Y
Sbjct: 543 QSRSRECDITKGKHSYNSRTRERSRSRDRS-------RRVRSRTH-----DRDRSRSKEY 590
Query: 525 DHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQE 584
H Y RE++ R G SR TP RS R + S ++D
Sbjct: 591 -HRY----REQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYR 645
Query: 585 DASDDALPPYSELELTRGPSYRGRDLPYHSNSEKKRKKEPAKKTNDF 631
+ + E + + RD H++S R+K+ + + F
Sbjct: 646 NQESKSSHRKENSESEKRMYSKSRD---HNSSNNSREKKADRDQSPF 689
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 37.0 bits (84), Expect = 0.056
Identities = 31/84 (36%), Positives = 37/84 (44%), Gaps = 7/84 (8%)
Query: 485 REPLTDADRGWAFSPAR-RRPAEDAHLPRLVSRTPGTAPKYDHSYLGSA---RERQARPE 540
REP T A RG+AF RR A+DA + G + + G R RQ P
Sbjct: 47 REPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPR 106
Query: 541 GASRGGSLETPSKRSAQLGPRSAS 564
G SRGG +RS G RS S
Sbjct: 107 GRSRGGGY---GRRSRSYGRRSRS 127
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
Query: 460 SESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPG 519
+ES + Q SL G+++ DRG + R L R +RTP
Sbjct: 1132 TESTDNRRVVQRSSLSRERGEKA--------GDRGDRLERSERGGDRGDRLDR--ARTPA 1181
Query: 520 TAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSS 579
T + +RER ++PEG + SL R R A A P KA S
Sbjct: 1182 TKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREA---ALPPVSPLKAALS 1238
Query: 580 QDDQEDASDDALPPYSEL 597
+++ E S + Y L
Sbjct: 1239 EEELEKKSKAIIEEYLHL 1256
>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
isoform 2 [Homo sapiens]
Length = 1512
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
Query: 460 SESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPG 519
+ES + Q SL G+++ DRG + R L R +RTP
Sbjct: 1045 TESTDNRRVVQRSSLSRERGEKA--------GDRGDRLERSERGGDRGDRLDR--ARTPA 1094
Query: 520 TAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSS 579
T + +RER ++PEG + SL R R A A P KA S
Sbjct: 1095 TKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREA---ALPPVSPLKAALS 1151
Query: 580 QDDQEDASDDALPPYSEL 597
+++ E S + Y L
Sbjct: 1152 EEELEKKSKAIIEEYLHL 1169
>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
Length = 1435
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
Query: 460 SESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPG 519
+ES + Q SL G+++ DRG + R L R +RTP
Sbjct: 968 TESTDNRRVVQRSSLSRERGEKA--------GDRGDRLERSERGGDRGDRLDR--ARTPA 1017
Query: 520 TAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSS 579
T + +RER ++PEG + SL R R A A P KA S
Sbjct: 1018 TKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREA---ALPPVSPLKAALS 1074
Query: 580 QDDQEDASDDALPPYSEL 597
+++ E S + Y L
Sbjct: 1075 EEELEKKSKAIIEEYLHL 1092
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
Query: 460 SESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPG 519
+ES + Q SL G+++ DRG + R L R +RTP
Sbjct: 1132 TESTDNRRVVQRSSLSRERGEKA--------GDRGDRLERSERGGDRGDRLDR--ARTPA 1181
Query: 520 TAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSS 579
T + +RER ++PEG + SL R R A A P KA S
Sbjct: 1182 TKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREA---ALPPVSPLKAALS 1238
Query: 580 QDDQEDASDDALPPYSEL 597
+++ E S + Y L
Sbjct: 1239 EEELEKKSKAIIEEYLHL 1256
>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
Length = 1403
Score = 36.2 bits (82), Expect = 0.095
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 13/138 (9%)
Query: 460 SESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPG 519
+ES + Q SL G+++ DRG + R L R +RTP
Sbjct: 936 TESTDNRRVVQRSSLSRERGEKA--------GDRGDRLERSERGGDRGDRLDR--ARTPA 985
Query: 520 TAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSS 579
T + +RER ++PEG + SL R R A A P KA S
Sbjct: 986 TKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREA---ALPPVSPLKAALS 1042
Query: 580 QDDQEDASDDALPPYSEL 597
+++ E S + Y L
Sbjct: 1043 EEELEKKSKAIIEEYLHL 1060
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 36.2 bits (82), Expect = 0.095
Identities = 61/272 (22%), Positives = 99/272 (36%), Gaps = 33/272 (12%)
Query: 364 SGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVP 423
+G +P SG G+ R P + R RH + R R++ G
Sbjct: 174 TGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHR-------RRDGQRGGS 226
Query: 424 AVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSR 483
S + + S +R A S + GG R S + + S +D + + +
Sbjct: 227 EASKSR-SRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKS 285
Query: 484 SREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAP--KYDHSYLG--SARERQARP 539
S+EP + A+ + ED P+ R +P D S + +++ ++R
Sbjct: 286 SKEPPS------AYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRK 339
Query: 540 EGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDD---------A 590
+ GG S+R PRS S Y+ +Y SS + D S +
Sbjct: 340 SPSPAGGGSSPYSRRL----PRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRS 395
Query: 591 LPPYSELELTRGPSYRGRDLPYHSNSEKKRKK 622
PYS + L R R R PY S + R +
Sbjct: 396 RSPYSPV-LRRSGKSRSRS-PYSSRHSRSRSR 425
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 36.2 bits (82), Expect = 0.095
Identities = 61/272 (22%), Positives = 99/272 (36%), Gaps = 33/272 (12%)
Query: 364 SGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVP 423
+G +P SG G+ R P + R RH + R R++ G
Sbjct: 174 TGGSGGSPASSSGTQRRGEGSERRPRRDRRSSSGRSKERHREHR-------RRDGQRGGS 226
Query: 424 AVSMDELAAFADSYGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSR 483
S + + S +R A S + GG R S + + S +D + + +
Sbjct: 227 EASKSR-SRHSHSGEERAEVAKSGSSSSSGGRRKSASATSSSSSSRKDRDSKAHRSRTKS 285
Query: 484 SREPLTDADRGWAFSPARRRPAEDAHLPRLVSRTPGTAP--KYDHSYLG--SARERQARP 539
S+EP + A+ + ED P+ R +P D S + +++ ++R
Sbjct: 286 SKEPPS------AYKEPPKAYREDKTEPKAYRRRRSLSPLGGRDDSPVSHRASQSLRSRK 339
Query: 540 EGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQEDASDD---------A 590
+ GG S+R PRS S Y+ +Y SS + D S +
Sbjct: 340 SPSPAGGGSSPYSRRL----PRSPSPYSRRRSPSYSRHSSYERGGDVSPSPYSSSSWRRS 395
Query: 591 LPPYSELELTRGPSYRGRDLPYHSNSEKKRKK 622
PYS + L R R R PY S + R +
Sbjct: 396 RSPYSPV-LRRSGKSRSRS-PYSSRHSRSRSR 425
>gi|153945755 zinc finger protein 608 [Homo sapiens]
Length = 1512
Score = 35.8 bits (81), Expect = 0.12
Identities = 67/308 (21%), Positives = 111/308 (36%), Gaps = 61/308 (19%)
Query: 260 PSVPL-----GGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYY 314
P PL GA SS P ++ + GGS S +G R +A D +
Sbjct: 915 PMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDIISSKDS 974
Query: 315 VEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYW 374
V K +++T ++ S L E S + S+ S + +P
Sbjct: 975 VVK-------------GHSSTTAQSSQLKESHSPYYHSYDPYYSPSY-------MHPGQV 1014
Query: 375 SGVMGGSSGASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRK----NFATGVP---AVSM 427
G+SG+++G + ++ED E + K+E L K N A+ P +V
Sbjct: 1015 GAPAAGNSGSTQGMKIKKESEEDAEK------KDKAEQLDSKKVDHNSASLQPQHQSVIT 1068
Query: 428 DELAAFADS--YGQRPRRADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSR 485
A A S YGQ G ++ A S Y+ E+YY + +
Sbjct: 1069 QRHPALAQSLYYGQYAY-----------GLYMDQKSLMATSPAYR-QQYEKYYEDQRLAE 1116
Query: 486 EPLTDADRG-------WAFSPARRRPAEDAHLP-RLVSRTPGT-APKYDHSYLGSARERQ 536
+ + RG + + ++P +S+ P T P +HS LG + +
Sbjct: 1117 QKMAQTGRGDCERKSELPLKELGKEETKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNK 1176
Query: 537 ARPEGASR 544
G S+
Sbjct: 1177 TEETGKSQ 1184
>gi|38026934 Rho guanine nucleotide exchange factor (GEF) 11 isoform
2 [Homo sapiens]
Length = 1562
Score = 35.4 bits (80), Expect = 0.16
Identities = 42/163 (25%), Positives = 61/163 (37%), Gaps = 23/163 (14%)
Query: 245 GYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTGGSHSVRKGYRIQADK 304
G PS G+ G PS P G + ++ P PPPL P G ++ +Q
Sbjct: 121 GSSPSSMGISGLQQDPS-PAGAPRITSVIPSPPPPPPLPPPQRITGPKPLQDP-EVQKHA 178
Query: 305 ERDSMKVLYYVEKELAQFDPARRMRGRYNNTISELSSLHEEDSNFRQSFHQMRSKQ---- 360
+ +L EKEL +R+ Y+ + L E + R + Q++ +Q
Sbjct: 179 TQILRNMLRQEEKEL------QRICEVYSRNPASLLEEQIEGARRRVTQLQLKIQQETGG 232
Query: 361 ----FPVSGDLESNP-------DYWSGVMGGSSGASRGPSAME 392
P+ GD P D G G SG R PS E
Sbjct: 233 SVDILPLYGDTSQRPSEGRLSLDSQEGDSGLDSGTERFPSLSE 275
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 35.4 bits (80), Expect = 0.16
Identities = 55/216 (25%), Positives = 79/216 (36%), Gaps = 42/216 (19%)
Query: 384 ASRGPSAMEYNKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELAAFADSYGQRPRR 443
A+ GP + ++ +R+ R + + + S A PA D S R R
Sbjct: 509 AAAGPPTRKKSRRERK--RSGEAKEAASSSSGTQPAPPAPASPWD-------SKKHRSRD 559
Query: 444 ADGNSHEARGGSRFERSESRAHSGFYQDDSLEEYYG--QRSRSREPLTDADRGWAFSPAR 501
SH + R RS SR+ S + S + G +RSRSRE R
Sbjct: 560 RKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSRE-------------KR 606
Query: 502 RRPAEDAHLPRLVSRTPGTAPKYDHSYLGSARERQARPEGASR-GGSLETPSKRSAQLGP 560
RR A P P T+ S+ R+ R G R GG + KRS G
Sbjct: 607 RRRRRSASPP------PATS--------SSSSSRRERHRGKHRDGGGSKKKKKRSRSRGE 652
Query: 561 R---SASYYAWSPPGTYKAGSSQDDQEDASDDALPP 593
+ S A +P +S D++ A+PP
Sbjct: 653 KRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPP 688
>gi|239756792 PREDICTED: hypothetical protein [Homo sapiens]
Length = 188
Score = 35.0 bits (79), Expect = 0.21
Identities = 13/22 (59%), Positives = 13/22 (59%), Gaps = 3/22 (13%)
Query: 211 CCPHSCCCYVRCPCCPDSCCCP 232
CC SCCC PCC SCC P
Sbjct: 167 CCRPSCCC---SPCCVSSCCQP 185
Score = 32.3 bits (72), Expect = 1.4
Identities = 13/24 (54%), Positives = 14/24 (58%), Gaps = 4/24 (16%)
Query: 211 CCPHSCC---CYVRCPCCPDSCCC 231
CC +CC CY R CC SCCC
Sbjct: 152 CCRPTCCQTTCY-RTTCCRPSCCC 174
Score = 30.4 bits (67), Expect = 5.2
Identities = 14/42 (33%), Positives = 15/42 (35%), Gaps = 16/42 (38%)
Query: 207 CWCQCCPHSCC----CYVRC------------PCCPDSCCCP 232
C CC +CC C C PCC SCC P
Sbjct: 4 CCSPCCQPTCCRTTCCRTTCWKPTTVTTCSSTPCCQPSCCVP 45
Score = 30.4 bits (67), Expect = 5.2
Identities = 13/28 (46%), Positives = 13/28 (46%), Gaps = 1/28 (3%)
Query: 207 CWCQCCPHSCCCYVRC-PCCPDSCCCPQ 233
C CC SCC C P C S CC Q
Sbjct: 71 CVASCCQPSCCSTPCCQPTCCGSSCCGQ 98
Score = 30.0 bits (66), Expect = 6.8
Identities = 11/21 (52%), Positives = 12/21 (57%), Gaps = 1/21 (4%)
Query: 211 CCPHSCCCYVRC-PCCPDSCC 230
CC SCC C PCC +CC
Sbjct: 37 CCQPSCCVPSCCQPCCHPTCC 57
Score = 30.0 bits (66), Expect = 6.8
Identities = 13/32 (40%), Positives = 15/32 (46%), Gaps = 6/32 (18%)
Query: 207 CWCQCCPHSC---CCYVRC---PCCPDSCCCP 232
C CC SC CC+ C CC +CC P
Sbjct: 38 CQPSCCVPSCCQPCCHPTCCQNTCCRTTCCQP 69
Score = 30.0 bits (66), Expect = 6.8
Identities = 12/27 (44%), Positives = 14/27 (51%), Gaps = 1/27 (3%)
Query: 207 CWCQCCPHSCCCYVRC-PCCPDSCCCP 232
C CC ++CC C P C SCC P
Sbjct: 52 CHPTCCQNTCCRTTCCQPTCVASCCQP 78
Score = 30.0 bits (66), Expect = 6.8
Identities = 12/30 (40%), Positives = 14/30 (46%), Gaps = 6/30 (20%)
Query: 207 CWCQCCPHSC---CCYVRC---PCCPDSCC 230
C CC +C CC C PCC +CC
Sbjct: 62 CRTTCCQPTCVASCCQPSCCSTPCCQPTCC 91
Score = 30.0 bits (66), Expect = 6.8
Identities = 13/32 (40%), Positives = 13/32 (40%), Gaps = 6/32 (18%)
Query: 207 CWCQCCPHSCCCYVRC------PCCPDSCCCP 232
C CC SCC C P C SCC P
Sbjct: 86 CQPTCCGSSCCGQTSCGSSCCQPICGSSCCQP 117
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,538,093
Number of Sequences: 37866
Number of extensions: 1441520
Number of successful extensions: 8574
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 211
Number of HSP's that attempted gapping in prelim test: 7293
Number of HSP's gapped (non-prelim): 1181
length of query: 639
length of database: 18,247,518
effective HSP length: 109
effective length of query: 530
effective length of database: 14,120,124
effective search space: 7483665720
effective search space used: 7483665720
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.