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Search of human proteins with 40353734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
(265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens] 535 e-152
gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens] 520 e-148
gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens] 442 e-124
gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 352 2e-97
gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 352 2e-97
gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens] 352 2e-97
gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens] 106 2e-23
gi|33391150 nucleoplasmin 2 [Homo sapiens] 85 6e-17
gi|55956788 nucleolin [Homo sapiens] 74 1e-13
gi|115529449 upstream binding transcription factor, RNA polymera... 55 5e-08
gi|115529451 upstream binding transcription factor, RNA polymera... 55 5e-08
gi|7657671 upstream binding transcription factor, RNA polymerase... 55 5e-08
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 52 5e-07
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 52 7e-07
gi|42740903 MTERF domain containing 2 [Homo sapiens] 51 9e-07
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 50 2e-06
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 50 3e-06
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 49 3e-06
gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens] 49 6e-06
gi|21735415 centromere protein B [Homo sapiens] 48 8e-06
gi|153791492 eukaryotic translation initiation factor 3, subunit... 48 1e-05
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 48 1e-05
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 48 1e-05
gi|18093112 ABT1-associated protein [Homo sapiens] 48 1e-05
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens] 47 1e-05
gi|56806673 high-mobility group box 1-like 1 [Homo sapiens] 47 2e-05
gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens] 47 2e-05
gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens] 46 4e-05
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 46 4e-05
gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens] 45 5e-05
>gi|40353734 nucleophosmin 1 isoform 2 [Homo sapiens]
Length = 265
Score = 535 bits (1379), Expect = e-152
Identities = 265/265 (100%), Positives = 265/265 (100%)
Query: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
Query: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
Query: 181 FDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFI 240
FDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFI
Sbjct: 181 FDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAKFI 240
Query: 241 NYVKNCFRMTDQEAIQDLWQWRKSL 265
NYVKNCFRMTDQEAIQDLWQWRKSL
Sbjct: 241 NYVKNCFRMTDQEAIQDLWQWRKSL 265
>gi|10835063 nucleophosmin 1 isoform 1 [Homo sapiens]
Length = 294
Score = 520 bits (1339), Expect = e-148
Identities = 265/294 (90%), Positives = 265/294 (90%), Gaps = 29/294 (9%)
Query: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
Query: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
Query: 181 FDDEEAEEKAPVK-----------------------------KGQESFKKQEKTPKTPKG 211
FDDEEAEEKAPVK KGQESFKKQEKTPKTPKG
Sbjct: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
Query: 212 PSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL 265
PSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL
Sbjct: 241 PSSVEDIKAKMQASIEKGGSLPKVEAKFINYVKNCFRMTDQEAIQDLWQWRKSL 294
>gi|83641870 nucleophosmin 1 isoform 3 [Homo sapiens]
Length = 259
Score = 442 bits (1137), Expect = e-124
Identities = 228/257 (88%), Positives = 228/257 (88%), Gaps = 29/257 (11%)
Query: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV
Sbjct: 1 MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIV 60
Query: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE
Sbjct: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD
Sbjct: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
Query: 181 FDDEEAEEKAPVK-----------------------------KGQESFKKQEKTPKTPKG 211
FDDEEAEEKAPVK KGQESFKKQEKTPKTPKG
Sbjct: 181 FDDEEAEEKAPVKKSIRDTPAKNAQKSNQNGKDSKPSSTPRSKGQESFKKQEKTPKTPKG 240
Query: 212 PSSVEDIKAKMQASIEK 228
PSSVEDIKAKMQASIEK
Sbjct: 241 PSSVEDIKAKMQASIEK 257
>gi|169161779 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 352 bits (902), Expect = 2e-97
Identities = 177/190 (93%), Positives = 178/190 (93%), Gaps = 6/190 (3%)
Query: 5 MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1 MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60
Query: 65 MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61 MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120
Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174
Query: 185 EAEEKAPVKK 194
EAEEK PVKK
Sbjct: 175 EAEEKVPVKK 184
>gi|169161624 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 352 bits (902), Expect = 2e-97
Identities = 177/190 (93%), Positives = 178/190 (93%), Gaps = 6/190 (3%)
Query: 5 MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1 MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60
Query: 65 MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61 MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120
Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174
Query: 185 EAEEKAPVKK 194
EAEEK PVKK
Sbjct: 175 EAEEKVPVKK 184
>gi|169162829 PREDICTED: similar to nucleophosmin 1 [Homo sapiens]
Length = 186
Score = 352 bits (902), Expect = 2e-97
Identities = 177/190 (93%), Positives = 178/190 (93%), Gaps = 6/190 (3%)
Query: 5 MDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEA 64
MDMDMSPLRPQNYLFGCELKADKD HFKVDNDENEHQLSLRTVSLGAG KDELHIVEAEA
Sbjct: 1 MDMDMSPLRPQNYLFGCELKADKDDHFKVDNDENEHQLSLRTVSLGAGTKDELHIVEAEA 60
Query: 65 MNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAE 124
MNY+GSPIKVTLATLKMS QPTVSLGGFEITPPVVLR KCGSGPVHISGQHLVAVEEDAE
Sbjct: 61 MNYKGSPIKVTLATLKMSAQPTVSLGGFEITPPVVLRFKCGSGPVHISGQHLVAVEEDAE 120
Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLA DEDDDDDD DDDDDDFDDE
Sbjct: 121 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAVDEDDDDDD------DDDDDDFDDE 174
Query: 185 EAEEKAPVKK 194
EAEEK PVKK
Sbjct: 175 EAEEKVPVKK 184
>gi|6857818 nucleophosmin/nucleoplasmin 3 [Homo sapiens]
Length = 178
Score = 106 bits (265), Expect = 2e-23
Identities = 58/139 (41%), Positives = 84/139 (60%), Gaps = 10/139 (7%)
Query: 10 SPLRPQNYLFGCELKAD-KDYHFKVDN-DENEHQLSLRTVSLGAGAKDELHIVEAEAMNY 67
+P+ ++ FGCEL + + FKV+ D+ EH L+L + L GAKDE ++VE A N+
Sbjct: 30 APVTMDSFFFGCELSGHTRSFTFKVEEEDDAEHVLALTMLCLTEGAKDECNVVEVVARNH 89
Query: 68 EGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAV-------- 119
+ I V +A LK+S QP +SL F++ PPV RLK GSGPV I+G+H +
Sbjct: 90 DHQEIAVPVANLKLSCQPMLSLDDFQLQPPVTFRLKSGSGPVRITGRHQIVTMSNDVSEE 149
Query: 120 EEDAESEDEEEEDVKLLSI 138
E + E ED +EE+V+L I
Sbjct: 150 ESEEEEEDSDEEEVELCPI 168
>gi|33391150 nucleoplasmin 2 [Homo sapiens]
Length = 214
Score = 85.1 bits (209), Expect = 6e-17
Identities = 64/211 (30%), Positives = 106/211 (50%), Gaps = 40/211 (18%)
Query: 18 LFGCELKADK-DYHFKVDNDENEH-QLSLRTVSLGAGAKDELHIVEA-EAMNYEGSPIK- 73
L+GCEL ++ + F+ + + +L L T+ LG AK+E+H VE N E ++
Sbjct: 18 LWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQP 77
Query: 74 VTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDV 133
VT+A+L+ SV P VS+ G +++PPV +L+ GSGPV +SGQ + E+EEEE
Sbjct: 78 VTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEE-- 135
Query: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
+E+++++D+ED+D D EE++PVK
Sbjct: 136 -------------------------GEEEEEEEEDDEDEDA--------DISLEEQSPVK 162
Query: 194 KGQESF-KKQEKTPKTPKGPSSVEDIKAKMQ 223
+ + +KQ K K E+I+A ++
Sbjct: 163 QVKRLVPQKQASVAKKKKLEKEEEEIRASVR 193
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 73.9 bits (180), Expect = 1e-13
Identities = 38/98 (38%), Positives = 60/98 (61%), Gaps = 7/98 (7%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSA---PGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
++D E +D EEE ++ GK++A P V + + + DED+DDDD+EDD++DD
Sbjct: 198 DDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDEDDD 257
Query: 177 DDDDFDDEEAEEKAPVK----KGQESFKKQEKTPKTPK 210
D+DD ++EE EE+ PVK K ++ KQ+ P+ K
Sbjct: 258 DEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAKK 295
Score = 62.0 bits (149), Expect = 5e-10
Identities = 28/74 (37%), Positives = 47/74 (63%), Gaps = 13/74 (17%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
EED E EDE+E++++ ++ +AP A++++DD+DDE+D+D+DDD++
Sbjct: 157 EEDDEDEDEDEDEIEPAAMKAAAAAP-------------ASEDEDDEDDEDDEDDDDDEE 203
Query: 180 DFDDEEAEEKAPVK 193
D +EEA E P K
Sbjct: 204 DDSEEEAMETTPAK 217
Score = 48.5 bits (114), Expect = 6e-06
Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 26/119 (21%)
Query: 135 LLSISGKRSA--PGGGSKVPQKKVKLAADEDDDDDDEEDDDED----------------- 175
L++ GK+ A P G+K + K +DE++DDD EED+++D
Sbjct: 118 LVATPGKKGAAIPAKGAKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKA 177
Query: 176 -------DDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIE 227
+D+DD DDE+ E+ ++ + E TP K + V +KAK A E
Sbjct: 178 AAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDE 236
Score = 32.3 bits (72), Expect = 0.44
Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 15/67 (22%)
Query: 134 KLLSISGKRSAPGG----------GSKVPQKKVKLAADEDDDDDDEEDDDEDDD--DDDF 181
K ++ GK+ A G G+ +P K K + +D DEE EDDD +D+
Sbjct: 102 KAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSDEE---EDDDSEEDEE 158
Query: 182 DDEEAEE 188
DDE+ +E
Sbjct: 159 DDEDEDE 165
Score = 30.0 bits (66), Expect = 2.2
Identities = 16/55 (29%), Positives = 30/55 (54%), Gaps = 3/55 (5%)
Query: 144 APGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQES 198
A G ++ KK+ E ++D ++E+ ED++DD +E P KKG+++
Sbjct: 5 AKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVV---IPQKKGKKA 56
Score = 29.6 bits (65), Expect = 2.8
Identities = 16/66 (24%), Positives = 30/66 (45%)
Query: 141 KRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFK 200
K + G P+K + ++D +DEE ++++DD ++ +K K S K
Sbjct: 3 KLAKAGKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAK 62
Query: 201 KQEKTP 206
K +P
Sbjct: 63 KVVVSP 68
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.5 bits (132), Expect = 5e-08
Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 5/68 (7%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
+ED E EDEEEED + +G S GG S + + + D D++++D+ED+D+D+DDD
Sbjct: 647 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 701
Query: 180 DFDDEEAE 187
+ +D E+E
Sbjct: 702 EDEDNESE 709
Score = 42.4 bits (98), Expect = 4e-04
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 18/160 (11%)
Query: 62 AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
++ M ++G P K + + Q +S G P ++ GS IS +H
Sbjct: 521 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 580
Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
+ E+ + + + D VK LS IS KR + G + + + E
Sbjct: 581 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 640
Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQE 203
++DD+E++DDED+D+++ DDE + ES + E
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE 680
Score = 37.4 bits (85), Expect = 0.014
Identities = 17/71 (23%), Positives = 34/71 (47%)
Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKA 220
DEDD+D+DEE++D+++ D D ++ E + + ++ + +E ED
Sbjct: 647 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDN 706
Query: 221 KMQASIEKGGS 231
+ + S S
Sbjct: 707 ESEGSSSSSSS 717
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 55.5 bits (132), Expect = 5e-08
Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 5/68 (7%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
+ED E EDEEEED + +G S GG S + + + D D++++D+ED+D+D+DDD
Sbjct: 647 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 701
Query: 180 DFDDEEAE 187
+ +D E+E
Sbjct: 702 EDEDNESE 709
Score = 42.4 bits (98), Expect = 4e-04
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 18/160 (11%)
Query: 62 AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
++ M ++G P K + + Q +S G P ++ GS IS +H
Sbjct: 521 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 580
Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
+ E+ + + + D VK LS IS KR + G + + + E
Sbjct: 581 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 640
Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQE 203
++DD+E++DDED+D+++ DDE + ES + E
Sbjct: 641 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE 680
Score = 37.4 bits (85), Expect = 0.014
Identities = 17/71 (23%), Positives = 34/71 (47%)
Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKA 220
DEDD+D+DEE++D+++ D D ++ E + + ++ + +E ED
Sbjct: 647 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDN 706
Query: 221 KMQASIEKGGS 231
+ + S S
Sbjct: 707 ESEGSSSSSSS 717
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 55.5 bits (132), Expect = 5e-08
Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 5/68 (7%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
+ED E EDEEEED + +G S GG S + + + D D++++D+ED+D+D+DDD
Sbjct: 684 DEDDEDEDEEEEDDE----NGDSSEDGGDSSESSSEDE-SEDGDENEEDDEDEDDDEDDD 738
Query: 180 DFDDEEAE 187
+ +D E+E
Sbjct: 739 EDEDNESE 746
Score = 42.4 bits (98), Expect = 4e-04
Identities = 39/160 (24%), Positives = 69/160 (43%), Gaps = 18/160 (11%)
Query: 62 AEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISG---QHLVA 118
++ M ++G P K + + Q +S G P ++ GS IS +H
Sbjct: 558 SKKMKFQGEPKKPPMNGYQKFSQELLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKK 617
Query: 119 VEEDAESEDEEEED--VKLLS----------ISGKRSAPG---GGSKVPQKKVKLAADED 163
+ E+ + + + D VK LS IS KR + G + + + E
Sbjct: 618 LAEEQQKQYKVHLDLWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSES 677
Query: 164 DDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQE 203
++DD+E++DDED+D+++ DDE + ES + E
Sbjct: 678 EEDDEEDEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDE 717
Score = 37.4 bits (85), Expect = 0.014
Identities = 17/71 (23%), Positives = 34/71 (47%)
Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKA 220
DEDD+D+DEE++D+++ D D ++ E + + ++ + +E ED
Sbjct: 684 DEDDEDEDEEEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDEDDDEDDDEDEDN 743
Query: 221 KMQASIEKGGS 231
+ + S S
Sbjct: 744 ESEGSSSSSSS 754
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 52.0 bits (123), Expect = 5e-07
Identities = 25/79 (31%), Positives = 45/79 (56%), Gaps = 1/79 (1%)
Query: 146 GGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKT 205
G S +P K ++ED+++DDEE+D+EDD+DD+ DD ++E + + E ++++
Sbjct: 593 GTDSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDESDDSQSESDSNSESDTEGSEEEDDD 652
Query: 206 PK-TPKGPSSVEDIKAKMQ 223
K + S E K M+
Sbjct: 653 DKDQDESDSDTEGEKTSMK 671
Score = 45.4 bits (106), Expect = 5e-05
Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 11/62 (17%)
Query: 139 SGKRSAPGG----------GSKVP-QKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187
+GKR GG G+ P +K+ + D D DDDD++D D+ D+DD D+E+ E
Sbjct: 1263 TGKRDTSGGIDLGEEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKE 1322
Query: 188 EK 189
+K
Sbjct: 1323 DK 1324
Score = 38.9 bits (89), Expect = 0.005
Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 22/94 (23%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
EED E EDEE+++ S S S + + ++E+DDD+D D+
Sbjct: 612 EEDDEEEDEEDDEDDESDDSQSESDSNSES------------DTEGSEEEDDDDKDQDES 659
Query: 180 DFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPS 213
D D E G+++ K KT + K PS
Sbjct: 660 DSDTE----------GEKTSMKLNKTTSSVKSPS 683
Score = 36.2 bits (82), Expect = 0.030
Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 134 KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVK 193
K + S + G S + ++D DD ++DEE++D+ ++ + DD ++E +A K
Sbjct: 237 KAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDSESEAQHK 296
Query: 194 KGQESFKKQEKTPKTPKGPSSVEDIKAK 221
+ PK G + E + K
Sbjct: 297 SNNQVLLHGISDPKA-DGQKATEKAQEK 323
Score = 35.0 bits (79), Expect = 0.068
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 4/81 (4%)
Query: 128 EEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDED----DDDDDFDD 183
EE+ + + KR GG S + D+ D+DD++E+D ED D D+
Sbjct: 1276 EEQHPLGTPTPGRKRRRKGGDSDYDDDDDDDSDDQGDEDDEDEEDKEDKKGKKTDICEDE 1335
Query: 184 EEAEEKAPVKKGQESFKKQEK 204
+E ++ A V++ ++ +K K
Sbjct: 1336 DEGDQAASVEELEKQIEKLSK 1356
Score = 34.7 bits (78), Expect = 0.088
Identities = 26/99 (26%), Positives = 46/99 (46%), Gaps = 15/99 (15%)
Query: 126 EDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDD---DEDDDDDDFD 182
+D++ + S S S G S + + + +D ++D+EE+D +E +DDD
Sbjct: 230 KDKKPRKKAMESSSNSDSDSGTSSDTSSEGISSSDSDDLEEDEEEEDQSIEESEDDDSDS 289
Query: 183 DEEAEEKA-----------PVKKGQESFKK-QEKTPKTP 209
+ EA+ K+ P GQ++ +K QEK P
Sbjct: 290 ESEAQHKSNNQVLLHGISDPKADGQKATEKAQEKRIHQP 328
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 51.6 bits (122), Expect = 7e-07
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 27/87 (31%)
Query: 118 AVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDD 177
+VE E ED+E ED ED+DD+D++DDD+DDD
Sbjct: 241 SVESSEEGEDQEHED---------------------------DGEDEDDEDDDDDDDDDD 273
Query: 178 DDDFDDEEAEEKAPVKKGQESFKKQEK 204
DDD +D+E EE + + + +Q K
Sbjct: 274 DDDDEDDEDEEDGEEENQKRYYLRQRK 300
Score = 34.7 bits (78), Expect = 0.088
Identities = 12/49 (24%), Positives = 31/49 (63%)
Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPK 207
+++E +D + E+D +++DD+DD DD++ ++ + ++ +E+ K
Sbjct: 244 SSEEGEDQEHEDDGEDEDDEDDDDDDDDDDDDDDEDDEDEEDGEEENQK 292
Score = 29.3 bits (64), Expect = 3.7
Identities = 14/54 (25%), Positives = 28/54 (51%)
Query: 161 DEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSS 214
D+DD+DD++E+D E+++ + + + + E + Q K GP+S
Sbjct: 274 DDDDEDDEDEEDGEEENQKRYYLRQRKATVYYQAPLEKPRHQRKPNIFYSGPAS 327
>gi|42740903 MTERF domain containing 2 [Homo sapiens]
Length = 381
Score = 51.2 bits (121), Expect = 9e-07
Identities = 23/35 (65%), Positives = 29/35 (82%), Gaps = 3/35 (8%)
Query: 157 KLAADEDDDDDDEEDDDEDD---DDDDFDDEEAEE 188
+ + DED+DDDDEED+DEDD DDDD DD+EAE+
Sbjct: 336 RASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAED 370
Score = 44.3 bits (103), Expect = 1e-04
Identities = 21/59 (35%), Positives = 35/59 (59%)
Query: 129 EEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAE 187
EEE+ + + KR++ ++ D D+DDDDE+DD+ +D+D+D DD+E E
Sbjct: 323 EEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/47 (36%), Positives = 34/47 (72%)
Query: 157 KLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQE 203
K A+ ++D+DDD+E+D+++DD+D+ DD+E +++A E ++E
Sbjct: 335 KRASLDEDEDDDDEEDNDEDDNDEDDDDEDDDEAEDNDEDEDDDEEE 381
Score = 29.6 bits (65), Expect = 2.8
Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 155 KVKLAADEDDDDDDEEDD-------DEDDDDDDFDDEEAEEK 189
K LA +E++ + DD DEDDDD++ +DE+ ++
Sbjct: 317 KKLLAREEEESESSTSDDKRASLDEDEDDDDEEDNDEDDNDE 358
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 50.1 bits (118), Expect = 2e-06
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 22/82 (26%)
Query: 113 GQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDD 172
G A S+++EEE+++L P+++ A D++D+DDDE+DD
Sbjct: 1662 GAAAAAAAAGESSQEDEEEELEL----------------PEEE---AEDDEDEDDDEDDD 1702
Query: 173 DEDDDDDDFDDE---EAEEKAP 191
DEDDD+DD D++ ++EE P
Sbjct: 1703 DEDDDEDDDDEDLRTDSEESLP 1724
Score = 44.3 bits (103), Expect = 1e-04
Identities = 19/56 (33%), Positives = 36/56 (64%)
Query: 143 SAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQES 198
+A G S ++ +L E++ +DDE++DD++DDDD+ DDE+ +++ +ES
Sbjct: 1667 AAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDDDEDLRTDSEES 1722
Score = 30.4 bits (67), Expect = 1.7
Identities = 18/90 (20%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 140 GKRSAPGGGSKVPQKKVKLAADEDDDDDDEED-----DDEDDDDDDFDDEEAEEKAPVKK 194
G A G + AA E +D+EE+ ++ +DD+D+ DDE+ +++ +
Sbjct: 1650 GPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDED 1709
Query: 195 GQESFKKQEKTPKTPKGPSSVEDIKAKMQA 224
+ + + P+ + A+ A
Sbjct: 1710 DDDEDLRTDSEESLPEAAAEAAGAGARTPA 1739
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 49.7 bits (117), Expect = 3e-06
Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 4/114 (3%)
Query: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182
A ++D+ ++ + +I ++S + +KK + D +++++D++DDD+D++D FD
Sbjct: 189 AVAKDKYKDTQSVSAIGEEKSHESKHQESVKKKGREEEDMEEEENDDDDDDDDEEDGVFD 248
Query: 183 DEEAEEKAPVKKGQESFKKQEKTPKTP----KGPSSVEDIKAKMQASIEKGGSL 232
DE+ EE+ K + + Q++ K P S ED + SI+ G L
Sbjct: 249 DEDEEEENIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDDGEEL 302
Score = 37.0 bits (84), Expect = 0.018
Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 6/90 (6%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADED---DDDDDEEDDDEDD 176
EED +DE+EE+ +I K + P K K+ A D +D D EE D DD
Sbjct: 242 EEDGVFDDEDEEEE---NIESKVTKPVQIQKRAVKRPAPAKSSDHSEEDSDLEESDSIDD 298
Query: 177 DDDDFDDEEAEEKAPVKKGQESFKKQEKTP 206
++ + + E+ K Q S KK+ K P
Sbjct: 299 GEELAQSDTSTEEQEDKAVQVSNKKKRKLP 328
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 49.3 bits (116), Expect = 3e-06
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 10/128 (7%)
Query: 118 AVEEDAESEDEEEEDV-----KLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDD 172
A D+E EEEE+V K ++ KR G + +++E DDDDEED
Sbjct: 82 ASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQ 141
Query: 173 DEDDDDDDFDDEEAEEKAPVKKGQES-----FKKQEKTPKTPKGPSSVEDIKAKMQASIE 227
+ + KAP KK + S +++ PK K + +KA+ +A +
Sbjct: 142 KKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK 201
Query: 228 KGGSLPKV 235
+ PK+
Sbjct: 202 PARAAPKI 209
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/180 (20%), Positives = 71/180 (39%), Gaps = 16/180 (8%)
Query: 61 EAEAMNYEGSPIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVE 120
++++ + +P K T S +P V+ + P + G G ++ + +
Sbjct: 367 DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSS 426
Query: 121 EDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDD 180
E+ S EEE+ K+++ + ++ +P K+ + + D D +E
Sbjct: 427 EEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEE------ 480
Query: 181 FDDEEAEEKAPVKKGQESFKKQEKTP--KTPKGPSSVEDIKAKMQASIEKGGSLPKVEAK 238
+EE K+ VK KK +K P P+S + KA+ S S + E K
Sbjct: 481 --EEEKTSKSAVK------KKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEK 532
Score = 39.3 bits (90), Expect = 0.004
Identities = 24/115 (20%), Positives = 44/115 (38%), Gaps = 1/115 (0%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
+ D+ S +EEEE ++ K GG+ P K + + + DD ++++
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGA-APSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 180 DFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPK 234
+ + + K + + K K E+ K K + K GSL K
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKK 585
Score = 37.4 bits (85), Expect = 0.014
Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 2/114 (1%)
Query: 121 EDAESEDEEEEDVKLLSISGKRSA-PGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
ED+ S++EEE+ + + G S+ P + P+K + + + + + +D D
Sbjct: 268 EDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSD 327
Query: 180 DFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLP 233
+ D EEK P K S K K P K S D + ++ S P
Sbjct: 328 ESDSSSEEEKKPPTKAVVS-KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP 380
Score = 33.1 bits (74), Expect = 0.26
Identities = 31/135 (22%), Positives = 48/135 (35%), Gaps = 26/135 (19%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
E D+ SE+E++ K + P P KK ++ + D D EDD+
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPP------PAKKAAESSSDSSDSDSSEDDEAPSKPA 381
Query: 180 DFDDEE----------------AEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQ 223
A K PV GQ+ ++ + + + SS E+ K K
Sbjct: 382 GTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKM 441
Query: 224 ASIEKGGSLPKVEAK 238
+ K PK AK
Sbjct: 442 VATTK----PKATAK 452
>gi|239744307 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 486
Score = 48.5 bits (114), Expect = 6e-06
Identities = 29/128 (22%), Positives = 59/128 (46%), Gaps = 4/128 (3%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
+ A+ +++ E+D+ GK A G K K +E++++D+E++++E D+D+
Sbjct: 282 KRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEDE 341
Query: 180 DFDDEEAEEKAPVKKGQESF----KKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKV 235
D +D+E EE ++ +++ P+ P++ I K S L
Sbjct: 342 DEEDDEDEEDGDDEQSHWQLFLACCPEDQRRLVPQCPANARAIACKTPVSFPPLSFLSAK 401
Query: 236 EAKFINYV 243
E +N V
Sbjct: 402 EGSDLNAV 409
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 48.1 bits (113), Expect = 8e-06
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 15/87 (17%)
Query: 117 VAVEEDAESEDEEEEDVKLLS--------ISGKRSAPGG-GSKVPQKKVK------LAAD 161
V E D +S++EEEED + S G A G G+ Q++ + L
Sbjct: 448 VEEEGDVDSDEEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGG 507
Query: 162 EDDDDDDEEDDDEDDDDDDFDDEEAEE 188
ED D D EE+DDE++DD+D DD++ EE
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEE 534
Score = 37.0 bits (84), Expect = 0.018
Identities = 32/129 (24%), Positives = 59/129 (45%), Gaps = 34/129 (26%)
Query: 105 GSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDD 164
G GP L + E+ E E+EEEE+ + G G +E++
Sbjct: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEE-----------GEG------------EEEE 426
Query: 165 DDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAK--M 222
++ +EE+++ + ++ ++EE EE+ V +E + +E SS E ++A+
Sbjct: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE---------SSSEGLEAEDWA 477
Query: 223 QASIEKGGS 231
Q +E GGS
Sbjct: 478 QGVVEAGGS 486
Score = 35.4 bits (80), Expect = 0.052
Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 28/65 (43%)
Query: 115 HLVAVEEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDE 174
H + ED++S+ EEE+D +E+DD+D+++DDDE
Sbjct: 502 HFLEGGEDSDSDSEEEDD----------------------------EEEDDEDEDDDDDE 533
Query: 175 DDDDD 179
+D D+
Sbjct: 534 EDGDE 538
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 17/112 (15%)
Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
EED+E EDE+E+ V + K+S AP G S+ KK+ DD+D++ +D ED
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKM-------DDEDEDSEDSED 227
Query: 176 DDDDDF------DDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAK 221
D+D D D E EE KK T + K + KAK
Sbjct: 228 DEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAK 279
Score = 30.0 bits (66), Expect = 2.2
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEA------EEKAPVKKGQESFKKQEKTPKTPKGP 212
+ADED + ++E+ + D+D+D D A + +AP + ++ KK + + +
Sbjct: 166 SADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDS 225
Query: 213 SSVED 217
ED
Sbjct: 226 EDDED 230
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 17/112 (15%)
Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
EED+E EDE+E+ V + K+S AP G S+ KK+ DD+D++ +D ED
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKM-------DDEDEDSEDSED 227
Query: 176 DDDDDF------DDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAK 221
D+D D D E EE KK T + K + KAK
Sbjct: 228 DEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAK 279
Score = 30.0 bits (66), Expect = 2.2
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEA------EEKAPVKKGQESFKKQEKTPKTPKGP 212
+ADED + ++E+ + D+D+D D A + +AP + ++ KK + + +
Sbjct: 166 SADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDS 225
Query: 213 SSVED 217
ED
Sbjct: 226 EDDED 230
Score = 28.5 bits (62), Expect = 6.3
Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 118 AVEEDAESEDEEEEDVKLLS-ISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
+ D++SE+EE + L S K K +KK + A + D + D+E++
Sbjct: 235 STSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294
Query: 177 DDDDFDDEEAEEKAP-VKKGQESFKK 201
D++ + E P VK+ + F K
Sbjct: 295 DNEGGEWERVRGGVPLVKEKPKMFAK 320
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 47.8 bits (112), Expect = 1e-05
Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 17/112 (15%)
Query: 120 EEDAES---EDEEEEDVKLLSISGKRS-APGGGSKVPQKKVKLAADEDDDDDDEEDDDED 175
EED+E EDE+E+ V + K+S AP G S+ KK+ DD+D++ +D ED
Sbjct: 175 EEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKM-------DDEDEDSEDSED 227
Query: 176 DDDDDF------DDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAK 221
D+D D D E EE KK T + K + KAK
Sbjct: 228 DEDWDTGSTSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAK 279
Score = 30.0 bits (66), Expect = 2.2
Identities = 16/65 (24%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 159 AADEDDDDDDEEDDDEDDDDDDFDDEEA------EEKAPVKKGQESFKKQEKTPKTPKGP 212
+ADED + ++E+ + D+D+D D A + +AP + ++ KK + + +
Sbjct: 166 SADEDAEKNEEDSEGSSDEDEDEDGVSAATFLKKKSEAPSGESRKFLKKMDDEDEDSEDS 225
Query: 213 SSVED 217
ED
Sbjct: 226 EDDED 230
Score = 28.5 bits (62), Expect = 6.3
Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 118 AVEEDAESEDEEEEDVKLLS-ISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD 176
+ D++SE+EE + L S K K +KK + A + D + D+E++
Sbjct: 235 STSSDSDSEEEEGKQTALASRFLKKAPTTDEDKKAAEKKREDKAKKKHDRKSKRLDEEEE 294
Query: 177 DDDDFDDEEAEEKAP-VKKGQESFKK 201
D++ + E P VK+ + F K
Sbjct: 295 DNEGGEWERVRGGVPLVKEKPKMFAK 320
>gi|18093112 ABT1-associated protein [Homo sapiens]
Length = 851
Score = 47.8 bits (112), Expect = 1e-05
Identities = 27/69 (39%), Positives = 40/69 (57%), Gaps = 12/69 (17%)
Query: 118 AVEEDAESEDE---EEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDE 174
A+EED+ES E +EE ++ G+ S GS+ DE++D+D+EED+DE
Sbjct: 238 ALEEDSESVSEIGSDEESENEITSVGRASGDDDGSE---------DDEEEDEDEEEDEDE 288
Query: 175 DDDDDDFDD 183
D +DDD D
Sbjct: 289 DSEDDDKSD 297
Score = 37.0 bits (84), Expect = 0.018
Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 9/92 (9%)
Query: 125 SEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDE 184
S D E D L + + G + + ++ DDD EDD+E+D+D++ D++
Sbjct: 228 STDGEMCDKDALEEDSESVSEIGSDEESENEITSVGRASGDDDGSEDDEEEDEDEEEDED 287
Query: 185 EAEEKAPVKKGQESFKKQEKTPKTPKGPSSVE 216
E E K + P +G ++E
Sbjct: 288 E---------DSEDDDKSDSGPDLARGKGNIE 310
>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
Length = 224
Score = 47.4 bits (111), Expect = 1e-05
Identities = 26/72 (36%), Positives = 45/72 (62%), Gaps = 11/72 (15%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
E D SE EEEE+ + + S S+P S V + DDD++DEE+++E+++++
Sbjct: 10 EFDTISELEEEEEEEAATSS---SSPSSSSSV--------SGPDDDEEDEEEEEEEEEEE 58
Query: 180 DFDDEEAEEKAP 191
+ ++EE EE+AP
Sbjct: 59 EEEEEEEEEEAP 70
>gi|56806673 high-mobility group box 1-like 1 [Homo sapiens]
Length = 211
Score = 47.0 bits (110), Expect = 2e-05
Identities = 19/63 (30%), Positives = 40/63 (63%)
Query: 123 AESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFD 182
A+ +++ E+D+ GK A G +K K +E+D++D+E++++ED++D++ D
Sbjct: 149 AKLKEKYEKDIAAYQAKGKPEAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEDEEDEEDD 208
Query: 183 DEE 185
D+E
Sbjct: 209 DDE 211
>gi|86262149 zinc finger and BTB domain containing 7C [Homo sapiens]
Length = 619
Score = 46.6 bits (109), Expect = 2e-05
Identities = 19/44 (43%), Positives = 29/44 (65%)
Query: 163 DDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKKQEKTP 206
++DD +++DDDEDDDD++ ++EE EE+ E F QE P
Sbjct: 135 EEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLP 178
Score = 42.4 bits (98), Expect = 4e-04
Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 145 PGGGSKVPQKKVKLAADEDDDD---DDEEDDDEDDDDDDFDDEEAEEKAPVKKGQESFKK 201
PGG K DEDDDD ++EE+++E+DDDDD +D +E P + +
Sbjct: 129 PGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDPQDISCHQS 188
Query: 202 QEKT 205
KT
Sbjct: 189 PSKT 192
Score = 29.3 bits (64), Expect = 3.7
Identities = 20/88 (22%), Positives = 36/88 (40%), Gaps = 28/88 (31%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
E+D + EDEEEE+ +E++DDDD+ +D D ++
Sbjct: 146 EDDDDEEDEEEEE----------------------------EEEEDDDDDTEDFADQENL 177
Query: 180 DFDDEEAEEKAPVKKGQESFKKQEKTPK 207
+ + ++P K + K TP+
Sbjct: 178 PDPQDISCHQSPSKTDHLTEKAYSDTPR 205
>gi|239749996 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 487
Score = 45.8 bits (107), Expect = 4e-05
Identities = 30/129 (23%), Positives = 60/129 (46%), Gaps = 5/129 (3%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD--D 177
+ A+ +++ E+D+ GK A G K K +E++++D+E++++E D D
Sbjct: 282 KRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEED 341
Query: 178 DDDFDDEEAEEKAPVKKGQESFK---KQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPK 234
+D+ DDE+ E+ + + F +++ P+ P++ I K S L
Sbjct: 342 EDEEDDEDEEDGDDEQSHWQLFLACCPEDQRRLVPQCPANARAIACKTPVSFPPLSFLSA 401
Query: 235 VEAKFINYV 243
E +N V
Sbjct: 402 KEGSDLNAV 410
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 45.8 bits (107), Expect = 4e-05
Identities = 32/120 (26%), Positives = 60/120 (50%), Gaps = 5/120 (4%)
Query: 121 EDAESEDEEEEDVKLLS--ISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDD 178
ED++ D E ++V +S S + P +K PQ++ ++ D EE ++E +
Sbjct: 259 EDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPE 318
Query: 179 DDFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLPKVEAK 238
+D ++EE E+KAP QE ++++ + ++ S D +A + K + PK E K
Sbjct: 319 EDKEEEE-EKKAPTP--QEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERK 375
Score = 38.9 bits (89), Expect = 0.005
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
Query: 130 EEDVKLLSISGKRSAPGGGSKVPQ--KKVKLAADEDDDDDDEEDDD---EDDDDDDFDDE 184
E+D+++ S + S GG +VP+ KK LA + DD ED DD DF+ +
Sbjct: 211 EDDLEMSSDASDASGEEGG-RVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQ 269
Query: 185 EAEEKAP-VKKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEK 228
E + + QE + + K P+ +GP V++ + S E+
Sbjct: 270 EVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEE 314
Score = 28.9 bits (63), Expect = 4.8
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 15/95 (15%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDD 179
EE ED+EEE+ K K P +KK + + E+ D +E D D +
Sbjct: 313 EEKPPEEDKEEEEEK------KAPTP------QEKKRRKDSSEESDSSEESDIDSEASSA 360
Query: 180 DFDDEEAEEKAPVKKGQESFKKQEKTPKTPKGPSS 214
F A++K P K+ ++ + P PS+
Sbjct: 361 LF---MAKKKTPPKRERKPSGGSSRGNSRPGTPSA 392
>gi|169202818 PREDICTED: similar to hCG1991922 [Homo sapiens]
Length = 488
Score = 45.4 bits (106), Expect = 5e-05
Identities = 30/130 (23%), Positives = 59/130 (45%), Gaps = 6/130 (4%)
Query: 120 EEDAESEDEEEEDVKLLSISGKRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDD--D 177
+ A+ +++ E+D+ GK A G K K +E++++D+E++++E D D
Sbjct: 282 KRSAKLKEKYEKDIAAYRAKGKHDAANNGVVKAAKSKKKKEEEENEEDEEDEEEEKDEED 341
Query: 178 DDDFDDEEAEEKAPVKKGQESF----KKQEKTPKTPKGPSSVEDIKAKMQASIEKGGSLP 233
+D+ DDE+ EE ++ +++ P+ P++ I K S L
Sbjct: 342 EDEEDDEDEEEDGDDEQSHWQLFLACCPEDQRRLVPQCPANARAIACKTPVSFPPLSFLS 401
Query: 234 KVEAKFINYV 243
E +N V
Sbjct: 402 AKEGSDLNAV 411
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.130 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,692,145
Number of Sequences: 37866
Number of extensions: 633699
Number of successful extensions: 21251
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 662
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 6237
Number of HSP's gapped (non-prelim): 6085
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.