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Search of human proteins with 40255101
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40255101 solute carrier family 39 (zinc transporter), member
13 isoform b [Homo sapiens]
(364 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40255101 solute carrier family 39 (zinc transporter), member ... 724 0.0
gi|190014617 solute carrier family 39 (zinc transporter), member... 717 0.0
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 189 3e-48
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 189 3e-48
gi|115430259 solute carrier family 39 (zinc transporter), member... 116 3e-26
gi|115430255 solute carrier family 39 (zinc transporter), member... 116 3e-26
gi|223633937 solute carrier family 39 (zinc transporter), member... 103 2e-22
gi|206597541 solute carrier family 39 (metal ion transporter), m... 103 2e-22
gi|206597539 solute carrier family 39 (metal ion transporter), m... 103 2e-22
gi|223633939 solute carrier family 39 (zinc transporter), member... 100 3e-21
gi|187936949 solute carrier family 39 (zinc transporter), member... 87 3e-17
gi|55741750 solute carrier family 39 (zinc transporter), member ... 87 3e-17
gi|190358541 solute carrier family 39 (zinc transporter), member... 85 9e-17
gi|205830424 solute carrier family 39 (zinc transporter), member... 84 2e-16
gi|190360568 solute carrier family 39 (zinc transporter), member... 84 2e-16
gi|153252201 solute carrier family 39 (zinc transporter), member... 81 2e-15
gi|205830426 solute carrier family 39 (zinc transporter), member... 76 4e-14
gi|153252214 solute carrier family 39 (zinc transporter), member... 74 2e-13
gi|24586665 solute carrier family 39 (zinc transporter), member ... 74 2e-13
gi|205830407 solute carrier family 39 (zinc transporter), member... 74 2e-13
gi|205830405 solute carrier family 39 (zinc transporter), member... 74 2e-13
gi|205830403 solute carrier family 39 (zinc transporter), member... 74 2e-13
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 43 5e-04
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 42 9e-04
gi|40254928 solute carrier family 39 (zinc transporter), member ... 42 9e-04
gi|21361423 solute carrier family 39 (zinc transporter), member ... 41 0.001
gi|32490561 solute carrier family 39 (zinc transporter), member ... 41 0.002
gi|169163921 PREDICTED: hypothetical protein isoform 1 [Homo sap... 34 0.18
gi|88954747 PREDICTED: hypothetical protein isoform 7 [Homo sapi... 34 0.18
gi|41190403 PREDICTED: hypothetical protein isoform 1 [Homo sapi... 34 0.18
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 724 bits (1868), Expect = 0.0
Identities = 364/364 (100%), Positives = 364/364 (100%)
Query: 1 MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL 60
MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL
Sbjct: 1 MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL 60
Query: 61 SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN 120
SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN
Sbjct: 61 SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN 120
Query: 121 VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA 180
VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA
Sbjct: 121 VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA 180
Query: 181 PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF 240
PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF
Sbjct: 181 PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF 240
Query: 241 LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT 300
LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT
Sbjct: 241 LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT 300
Query: 301 QSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360
QSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS
Sbjct: 301 QSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360
Query: 361 LFVD 364
LFVD
Sbjct: 361 LFVD 364
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 717 bits (1850), Expect = 0.0
Identities = 364/371 (98%), Positives = 364/371 (98%), Gaps = 7/371 (1%)
Query: 1 MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL 60
MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL
Sbjct: 1 MPGCPCPGCGMAGPRLLFLTALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALL 60
Query: 61 SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN 120
SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN
Sbjct: 61 SGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGN 120
Query: 121 VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA 180
VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA
Sbjct: 121 VFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTSQA 180
Query: 181 PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF 240
PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF
Sbjct: 181 PNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASF 240
Query: 241 LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT 300
LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT
Sbjct: 241 LVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICT 300
Query: 301 QSPKGV-------EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGI 353
QSPKGV EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGI
Sbjct: 301 QSPKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGI 360
Query: 354 VVMVLFSLFVD 364
VVMVLFSLFVD
Sbjct: 361 VVMVLFSLFVD 371
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 189 bits (480), Expect = 3e-48
Identities = 129/359 (35%), Positives = 186/359 (51%), Gaps = 61/359 (16%)
Query: 52 ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111
ES + G + + W +L ++++ + F L +IP+E + L+ LLS
Sbjct: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
Query: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162
FA GGLLG+ FLHL+P A ++ PG G+G L +GLWV++GI+ F
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
Query: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192
L +EK +KE+ +S+ K+
Sbjct: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
Query: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246
G G Q A E G ++VSGYLNL A+ NFT GLA+ ASF + +
Sbjct: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
Query: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306
G+LTTM +LLHE+PHEVGDFAIL+++G + A +LQL TA+G L G A+ T+
Sbjct: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVG 407
Query: 307 EETA-----AWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360
E A WVLPFT+GGF+Y+A V+VLP+LL E P +SL ++L L G+++MVL +
Sbjct: 408 SEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIA 466
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 189 bits (480), Expect = 3e-48
Identities = 129/359 (35%), Positives = 186/359 (51%), Gaps = 61/359 (16%)
Query: 52 ESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLS 111
ES + G + + W +L ++++ + F L +IP+E + L+ LLS
Sbjct: 119 ESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSL----LQILLS 174
Query: 112 FALGGLLGNVFLHLLPEAW---AYTCSASPG------GEGQSLQQQQQLGLWVIAGILTF 162
FA GGLLG+ FLHL+P A ++ PG G+G L +GLWV++GI+ F
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILS----VGLWVLSGIVAF 230
Query: 163 LALEKMFL------------------------------DSKEEGTSQAPNKDPTAAAAAL 192
L +EK +KE+ +S+ K+
Sbjct: 231 LVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRR 290
Query: 193 NG------GHCLAQPAAEPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLVSKKI 246
G G Q A E G ++VSGYLNL A+ NFT GLA+ ASF + +
Sbjct: 291 GGSTVPKDGPVRPQNAEEEKRGL---DLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGL 347
Query: 247 GLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGV 306
G+LTTM +LLHE+PHEVGDFAIL+++G + A +LQL TA+G L G A+ T+
Sbjct: 348 GILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVG 407
Query: 307 EETA-----AWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLLLCAGIVVMVLFS 360
E A WVLPFT+GGF+Y+A V+VLP+LL E P +SL ++L L G+++MVL +
Sbjct: 408 SEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIA 466
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 116 bits (291), Expect = 3e-26
Identities = 113/366 (30%), Positives = 165/366 (45%), Gaps = 56/366 (15%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 273 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 325
Query: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 326 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 380
Query: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 381 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 436
Query: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 437 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 496
Query: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 497 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAV-- 554
Query: 303 PKGV-EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAGIVVMVL 358
GV EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G V++L
Sbjct: 555 --GVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLL 612
Query: 359 FSLFVD 364
SL+ D
Sbjct: 613 LSLYED 618
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 116 bits (291), Expect = 3e-26
Identities = 113/366 (30%), Positives = 165/366 (45%), Gaps = 56/366 (15%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 298 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 350
Query: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 351 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 405
Query: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 406 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 461
Query: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521
Query: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAV-- 579
Query: 303 PKGV-EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAGIVVMVL 358
GV EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G V++L
Sbjct: 580 --GVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLL 637
Query: 359 FSLFVD 364
SL+ D
Sbjct: 638 LSLYED 643
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 103 bits (258), Expect = 2e-22
Identities = 77/268 (28%), Positives = 134/268 (50%), Gaps = 31/268 (11%)
Query: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
Query: 164 ALEKMFLDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRSIKVSGYLNLL 223
+EK F+ ++P AAE +G++ S + ++LL
Sbjct: 460 LIEKCFILLVSPNDKKSPEDSQ----------------AAEMPIGSMTASNRKCKAISLL 503
Query: 224 A------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
A +++ NF GLA+ A+F S + G+ TT+AIL HEIPHE+GDFA+LL +G
Sbjct: 504 AIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMK 563
Query: 278 SAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDL--LE 335
+A + ++L +G + + V++ W+ T+G FLY++LV +LP++ ++
Sbjct: 564 TAILMNFISSLTAFMGLYIGLSVSADPCVQD---WIFTVTAGMFLYLSLVEMLPEMTHVQ 620
Query: 336 EEDPWRS-LQQLLLLCAGIVVMVLFSLF 362
+ PW L Q L G + ++L +++
Sbjct: 621 TQRPWMMFLLQNFGLILGWLSLLLLAIY 648
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 103 bits (257), Expect = 2e-22
Identities = 101/326 (30%), Positives = 145/326 (44%), Gaps = 47/326 (14%)
Query: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127
LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP
Sbjct: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
Query: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178
A A PGG + + GL V+ G+ LE M + G
Sbjct: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
Query: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219
+ N DP + AL +P A+ P L G+
Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
Query: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
+ LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G
Sbjct: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
Query: 278 SAAKLQLSTALGGLLGAGFAIC-TQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEE 336
S +L L + + G LG G A+ G WV T+G FLY+ALV++LP LL
Sbjct: 441 SFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRP 500
Query: 337 EDPWRS----LQQLLLLCAGIVVMVL 358
+P + LQ L LL G +++ +
Sbjct: 501 PEPLPTPHVLLQGLGLLLGGGLMLAI 526
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 103 bits (257), Expect = 2e-22
Identities = 101/326 (30%), Positives = 145/326 (44%), Gaps = 47/326 (14%)
Query: 72 LLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSF----ALGGLLGNVFLHLLP 127
LL +L+ V LL +P + +L G L+ LL F A+G L G+ LHLLP
Sbjct: 209 LLSALLQSALAVL-LLSLPSPLSLLLLRLLGPRLLRPLLGFLGALAVGTLCGDALLHLLP 267
Query: 128 EAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALEKMFLDSKEEGTS--------- 178
A A PGG + + GL V+ G+ LE M + G
Sbjct: 268 HAQEGR-HAGPGGLPE---KDLGPGLSVLGGLFLLFVLENMLGLLRHRGLRPRCCRRKRR 323
Query: 179 --QAPNKDP-TAAAAALNGGHCLAQPAAE----------PGLGAVVRSIKVSGY------ 219
+ N DP + AL +P A+ P L G+
Sbjct: 324 NLETRNLDPENGSGMALQPLQAAPEPGAQGQREKNSQHPPALAPPGHQGHSHGHQGGTDI 383
Query: 220 --LNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRW 277
+ LL + + N T GLA+ A+F GL TT+A+ HE+PHE+GDFA+LL++G
Sbjct: 384 TWMVLLGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGL--- 440
Query: 278 SAAKLQLSTALGGLLGAGFAIC-TQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEE 336
S +L L + + G LG G A+ G WV T+G FLY+ALV++LP LL
Sbjct: 441 SFRRLLLLSLVSGALGLGGAVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRP 500
Query: 337 EDPWRS----LQQLLLLCAGIVVMVL 358
+P + LQ L LL G +++ +
Sbjct: 501 PEPLPTPHVLLQGLGLLLGGGLMLAI 526
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 99.8 bits (247), Expect = 3e-21
Identities = 83/289 (28%), Positives = 142/289 (49%), Gaps = 36/289 (12%)
Query: 106 LKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP--GGEGQSLQQQQQLGLWVIAGILTFL 163
L+ + A+G L G+ LHL+P+ +P G +S +L + +I GI F
Sbjct: 401 LQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIWKL-MGLIGGIHGFF 459
Query: 164 ALEKMFL----DSKEEGTSQAPNKDPTAAAAALNGGHC-------------LAQP----A 202
+EK F+ + ++G S + ALN L P A
Sbjct: 460 LIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSASTIQLKSPEDSQA 519
Query: 203 AEPGLGAVVRSIKVSGYLNLLA------NTIDNFTHGLAVAASFLVSKKIGLLTTMAILL 256
AE +G++ S + ++LLA +++ NF GLA+ A+F S + G+ TT+AIL
Sbjct: 520 AEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSSSSESGVTTTIAILC 579
Query: 257 HEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPF 316
HEIPHE+GDFA+LL +G +A + ++L +G + + V++ W+
Sbjct: 580 HEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSADPCVQD---WIFTV 636
Query: 317 TSGGFLYIALVNVLPDL--LEEEDPWRS-LQQLLLLCAGIVVMVLFSLF 362
T+G FLY++LV +LP++ ++ + PW L Q L G + ++L +++
Sbjct: 637 TAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 685
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 86.7 bits (213), Expect = 3e-17
Identities = 51/155 (32%), Positives = 86/155 (55%), Gaps = 11/155 (7%)
Query: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
++ ++ + I NF+ GLA+ A+F G+ T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 671 WMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQ 730
Query: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLL---- 334
A L +A+ + G I T + W+ T+G FLY+ALV++LP++L
Sbjct: 731 AIVYNLLSAMMAYI--GMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDG 788
Query: 335 -EEEDPWRSLQQLLL----LCAGIVVMVLFSLFVD 364
EE + + Q +L L G +M++ +L+ D
Sbjct: 789 DNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 20/127 (15%)
Query: 68 WICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLP 127
WIC ++ ++ L + ++++P+ + + L L++ A+G + G+ LHLLP
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-----INQGCFKFLLTFLVALAVGTMSGDALLHLLP 461
Query: 128 EA---------WAYTCSASPGGEGQSLQQQQQL---GLWVIAGILTFLALE---KMFLDS 172
+ A+ S G E ++ GL + GI +E +MF
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHY 521
Query: 173 KEEGTSQ 179
K++ Q
Sbjct: 522 KQQRGKQ 528
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 86.7 bits (213), Expect = 3e-17
Identities = 51/155 (32%), Positives = 86/155 (55%), Gaps = 11/155 (7%)
Query: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
++ ++ + I NF+ GLA+ A+F G+ T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 671 WMVIMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQ 730
Query: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLL---- 334
A L +A+ + G I T + W+ T+G FLY+ALV++LP++L
Sbjct: 731 AIVYNLLSAMMAYI--GMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDG 788
Query: 335 -EEEDPWRSLQQLLL----LCAGIVVMVLFSLFVD 364
EE + + Q +L L G +M++ +L+ D
Sbjct: 789 DNEEHGFCPVGQFILQNLGLLFGFAIMLVIALYED 823
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/127 (22%), Positives = 54/127 (42%), Gaps = 20/127 (15%)
Query: 68 WICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLP 127
WIC ++ ++ L + ++++P+ + + L L++ A+G + G+ LHLLP
Sbjct: 407 WICGIISITVISLLSLLGVILVPI-----INQGCFKFLLTFLVALAVGTMSGDALLHLLP 461
Query: 128 EA---------WAYTCSASPGGEGQSLQQQQQL---GLWVIAGILTFLALE---KMFLDS 172
+ A+ S G E ++ GL + GI +E +MF
Sbjct: 462 HSQGGHDHSHQHAHGHGHSHGHESNKFLEEYDAVLKGLVALGGIYLLFIIEHCIRMFKHY 521
Query: 173 KEEGTSQ 179
K++ Q
Sbjct: 522 KQQRGKQ 528
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 85.1 bits (209), Expect = 9e-17
Identities = 97/385 (25%), Positives = 148/385 (38%), Gaps = 75/385 (19%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
P + + + AC +N+E+E G ++ W L ++ L+ + +LV+P
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCT 178
Query: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
L ++ ++G LL N L+PEA+ G
Sbjct: 179 EKAFFSRV-----LTYFIALSIGTLLSNALFQLIPEAF---------GFNPLEDYYVSKS 224
Query: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
V G F EK+ L SK EEG +
Sbjct: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
Query: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
AP D +L+ A +A L V S I ++ L++
Sbjct: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
Query: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
Query: 286 TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLE--EEDPWRS- 342
+A LG F I G +A W+ G FLYI+L ++ P++ E +ED +
Sbjct: 405 SACCCYLGLAFGILA----GSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGS 460
Query: 343 -----LQQLLLLCAGIVVMVLFSLF 362
+ Q L L G +MV+ +++
Sbjct: 461 ILIPFIIQNLGLLTGFTIMVVLTMY 485
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 84.0 bits (206), Expect = 2e-16
Identities = 98/385 (25%), Positives = 147/385 (38%), Gaps = 75/385 (19%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
P + + + AC +N+E+E G ++ W LL ++ L + V+P
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
T + L ++ A+G L N L+PEA+ G
Sbjct: 179 KKTFYKR-----LLLYFIALAIGTLYSNALFQLIPEAF---------GFNPLEDYYVSKS 224
Query: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
V G F EK+ L SK EEG +
Sbjct: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
Query: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
AP D +L+ A +A L V S I ++ L++
Sbjct: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
Query: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
Query: 286 TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLE--EEDPWRS- 342
+A LG F I G +A W+ G FLYI+L ++ P++ E +ED +
Sbjct: 405 SACCCYLGLAFGILA----GSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGS 460
Query: 343 -----LQQLLLLCAGIVVMVLFSLF 362
+ Q L L G +MV+ +++
Sbjct: 461 ILIPFIIQNLGLLTGFTIMVVLTMY 485
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 84.0 bits (206), Expect = 2e-16
Identities = 98/385 (25%), Positives = 147/385 (38%), Gaps = 75/385 (19%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
P + + + AC +N+E+E G ++ W LL ++ L + V+P
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
T + L ++ A+G L N L+PEA+ G
Sbjct: 179 KKTFYKR-----LLLYFIALAIGTLYSNALFQLIPEAF---------GFNPLEDYYVSKS 224
Query: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
V G F EK+ L SK EEG +
Sbjct: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
Query: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
AP D +L+ A +A L V S I ++ L++
Sbjct: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
Query: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
Query: 286 TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLE--EEDPWRS- 342
+A LG F I G +A W+ G FLYI+L ++ P++ E +ED +
Sbjct: 405 SACCCYLGLAFGILA----GSHFSANWIFALAGGMFLYISLADMFPEMNEVCQEDERKGS 460
Query: 343 -----LQQLLLLCAGIVVMVLFSLF 362
+ Q L L G +MV+ +++
Sbjct: 461 ILIPFIIQNLGLLTGFTIMVVLTMY 485
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 80.9 bits (198), Expect = 2e-15
Identities = 40/119 (33%), Positives = 69/119 (57%), Gaps = 2/119 (1%)
Query: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
++ ++ + + NF+ GLA+ A+F GL T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 597 WMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQ 656
Query: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPDLLEEE 337
A +A+ LG I E + W+ T+G F+Y+ALV+++P++L +
Sbjct: 657 AVLYNALSAMLAYLGMATGIFI--GHYAENVSMWIFALTAGLFMYVALVDMVPEMLHND 713
Score = 32.3 bits (72), Expect = 0.68
Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
PA+ ++ A +C + E ++ + W+ + ++ + ++++PL
Sbjct: 292 PAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNR 351
Query: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWA 131
+ + L L++ A+G L G+ FLHLLP + A
Sbjct: 352 VFFK-----FLLSFLVALAVGTLSGDAFLHLLPHSHA 383
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 76.3 bits (186), Expect = 4e-14
Identities = 95/378 (25%), Positives = 139/378 (36%), Gaps = 69/378 (18%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGE--RLDTWICSLLGSLMVGLSGVFPLLVIPLE 92
P + + + AC +N+E+E G ++ W LL ++ L + V+P
Sbjct: 119 PTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFM 178
Query: 93 MGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLG 152
T + L ++ A+G L N L+PEA+ G
Sbjct: 179 KKTFYKR-----LLLYFIALAIGTLYSNALFQLIPEAF---------GFNPLEDYYVSKS 224
Query: 153 LWVIAGILTFLALEKMF---------------------LDSK---EEGTSQ--------- 179
V G F EK+ L SK EEG +
Sbjct: 225 AVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDH 284
Query: 180 -------------APNKDPTAAAAALNGGHCLAQPAAEPGLGAVVRS-IKVSGYLNLLAN 225
AP D +L+ A +A L V S I ++ L++
Sbjct: 285 MIPQHCSSELDGKAPMVDEKVIVGSLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSD 344
Query: 226 TIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLS 285
+ NF GLA+ ASF VS G+ T++AIL E PHE+GDF ILL AG A
Sbjct: 345 GLHNFIDGLAIGASFTVSVFQGISTSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFL 404
Query: 286 TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLP--DLLEEEDPWRSL 343
+A LG F I G +A W+ G FLYI+L +++ + + W L
Sbjct: 405 SACCCYLGLAFGILA----GSHFSANWIFALAGGMFLYISLADMMEFCSVAQAGVQWCHL 460
Query: 344 QQLLLLCAGIVVMVLFSL 361
L L G+ + SL
Sbjct: 461 SSLQPLPLGLKRLSCLSL 478
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 74.3 bits (181), Expect = 2e-13
Identities = 38/112 (33%), Positives = 64/112 (57%), Gaps = 2/112 (1%)
Query: 219 YLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWS 278
++ ++ + + NF+ GLA+ A+F GL T++A+ HE+PHE+GDFA+LL+AG
Sbjct: 322 WMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQ 381
Query: 279 AAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVL 330
A +A+ LG I E + W+ T+G F+Y+ALV+++
Sbjct: 382 AVLYNALSAMLAYLGMATGIFI--GHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 32.3 bits (72), Expect = 0.68
Identities = 21/97 (21%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
PA+ ++ A +C + E ++ + W+ + ++ + ++++PL
Sbjct: 17 PAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNR 76
Query: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWA 131
+ + L L++ A+G L G+ FLHLLP + A
Sbjct: 77 VFFK-----FLLSFLVALAVGTLSGDAFLHLLPHSHA 108
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 73.9 bits (180), Expect = 2e-13
Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%)
Query: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 127 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 181
Query: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
+PEA+ + + + + V G E KM L + + G
Sbjct: 182 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 232
Query: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
++ T A A+NG C A PA EP +
Sbjct: 233 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 292
Query: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 293 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 352
Query: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326
ILL AG A +A +G F I G + G FLYI+L
Sbjct: 353 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 408
Query: 327 VNVLPDL 333
++ P++
Sbjct: 409 ADMFPEM 415
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 73.9 bits (180), Expect = 2e-13
Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%)
Query: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 60 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 114
Query: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
+PEA+ + + + + V G E KM L + + G
Sbjct: 115 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 165
Query: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
++ T A A+NG C A PA EP +
Sbjct: 166 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 225
Query: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 226 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 285
Query: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326
ILL AG A +A +G F I G + G FLYI+L
Sbjct: 286 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 341
Query: 327 VNVLPDL 333
++ P++
Sbjct: 342 ADMFPEM 348
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 73.9 bits (180), Expect = 2e-13
Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%)
Query: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 127 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 181
Query: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
+PEA+ + + + + V G E KM L + + G
Sbjct: 182 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 232
Query: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
++ T A A+NG C A PA EP +
Sbjct: 233 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 292
Query: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 293 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 352
Query: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326
ILL AG A +A +G F I G + G FLYI+L
Sbjct: 353 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 408
Query: 327 VNVLPDL 333
++ P++
Sbjct: 409 ADMFPEM 415
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 73.9 bits (180), Expect = 2e-13
Identities = 75/307 (24%), Positives = 117/307 (38%), Gaps = 57/307 (18%)
Query: 66 DTWICSLLGSLMVGLSGVFPLLVIPLEMGTMLRSEAGAWRLKQLLSFALGGLLGNVFLHL 125
+ W L ++ L+ + L++ PL ++ L + A+G L N L
Sbjct: 127 EVWGYGFLSVTIINLASLLGLILTPL-----IKKSYFPKILTFFVGLAIGTLFSNAIFQL 181
Query: 126 LPEAWAYTCSASPGGEGQSLQQQQQLGLWVIAGILTFLALE---KMFLDSKEE------G 176
+PEA+ + + + + V G E KM L + + G
Sbjct: 182 IPEAFGFD---------PKVDSYVEKAVAVFGGFYLLFFFERMLKMLLKTYGQNGHTHFG 232
Query: 177 TSQAPNKDPT---AAAAALNGGHCLAQPAA----------------------EPGLGAVV 211
++ T A A+NG C A PA EP +
Sbjct: 233 NDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCL 292
Query: 212 RSIKVS-----GYLNLLANTIDNFTHGLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDF 266
+ K+S ++ L + + NF GLA+ AS +S GL T++AIL E PHE+GDF
Sbjct: 293 KGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGDF 352
Query: 267 AILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIAL 326
ILL AG A +A +G F I G + G FLYI+L
Sbjct: 353 VILLNAGMSTRQALLFNFLSACSCYVGLAFGILV----GNNFAPNIIFALAGGMFLYISL 408
Query: 327 VNVLPDL 333
++ P++
Sbjct: 409 ADMFPEM 415
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 42.7 bits (99), Expect = 5e-04
Identities = 52/178 (29%), Positives = 74/178 (41%), Gaps = 29/178 (16%)
Query: 170 LDSKEEGTSQAPNKDPTAAAAALNGGHCLAQPA----AEPGLGAVVRSIKVSGYLNLLAN 225
+D E G + K AAA L G + P+ A+PG G+ R I L +LA
Sbjct: 143 IDKSENGEAYQRKK---AAATGLPEGPAVPVPSRGNLAQPG-GSSWRRIA----LLILAI 194
Query: 226 TIDNFTHGLAVAASFLVSKKIGLLT-------TMAILLHEIPHEVGDFAILLRAGFDRWS 278
TI N GLAV F +K T + I + P + L AGF W
Sbjct: 195 TIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWR 254
Query: 279 AAKL-QLS---TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPD 332
A QLS L G+ GA FA+ P + L F +G +Y+ + +++P+
Sbjct: 255 AFWYGQLSGMVEPLAGVFGA-FAVVLAEP-----ILPYALAFAAGAMVYVVMDDIIPE 306
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 42.0 bits (97), Expect = 9e-04
Identities = 52/177 (29%), Positives = 73/177 (41%), Gaps = 29/177 (16%)
Query: 171 DSKEEGTSQAPNKDPTAAAAALNGGHCLAQPA----AEPGLGAVVRSIKVSGYLNLLANT 226
D E G + K AAA L G + P+ A+PG G+ R I L +LA T
Sbjct: 151 DKSENGEAYQRKK---AAATGLPEGPAVPVPSRGNLAQPG-GSSWRRIA----LLILAIT 202
Query: 227 IDNFTHGLAVAASFLVSKKIGLLT-------TMAILLHEIPHEVGDFAILLRAGFDRWSA 279
I N GLAV F +K T + I + P + L AGF W A
Sbjct: 203 IHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGAGFSTWRA 262
Query: 280 AKL-QLS---TALGGLLGAGFAICTQSPKGVEETAAWVLPFTSGGFLYIALVNVLPD 332
QLS L G+ GA FA+ P + L F +G +Y+ + +++P+
Sbjct: 263 FWYGQLSGMVEPLAGVFGA-FAVVLAEP-----ILPYALAFAAGAMVYVVMDDIIPE 313
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 42.0 bits (97), Expect = 9e-04
Identities = 32/107 (29%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 233 GLAVAASFLVSK-KIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGG- 290
G+A+ A+ S+ + L+ +AI+LH+ P G + L+ AG +R K L AL
Sbjct: 160 GVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIRKHLLVFALAAP 219
Query: 291 --LLGAGFAICTQSPKGVEETAAW--VLPFTSGGFLYIALVNVLPDL 333
+ + S + + E A + F++G FLY+A V+VLP++
Sbjct: 220 VMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLPEV 266
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 41.2 bits (95), Expect = 0.001
Identities = 62/253 (24%), Positives = 105/253 (41%), Gaps = 19/253 (7%)
Query: 112 FALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLWVIA-GILTFLALEKMFL 170
FA G L L LLP+ Y + + Q L +++A G L +E++ L
Sbjct: 75 FAGGVFLATCLLDLLPD---YLAAIDEALAALHVTLQFPLQEFILAMGFFLVLVMEQITL 131
Query: 171 DSKEEGTSQAPNKDPTAAAAALNGG--HCLAQPAAEPGLGAVVRSIKVSGYLNLLANTID 228
KE+ + +P ++ A +NGG H P GA + + + + +
Sbjct: 132 AYKEQ-SGPSPLEETRALLGTVNGGPQHWHDGPGVPQASGAPATPSALRACVLVFSLALH 190
Query: 229 NFTHGLAVAASFLVSKKIGLLTTMAILLHE----IPHEVGDFAILLRAGFDRWSAAKLQL 284
+ GLAV ++ + L +A+LLH+ + + LRA
Sbjct: 191 SVFEGLAVGLQRDRARAMELC--LALLLHKGILAVSLSLRLLQSHLRAQVVAGCGILFSC 248
Query: 285 STALGGLLGAGFAICTQSPKGVEETAAWVLP-FTSGGFLYIALVNVLPDLLEEEDPWRSL 343
T LG LGA A +S + + A VL +G FLYI + +LP L + + +
Sbjct: 249 MTPLGIGLGAALA---ESAGPLHQLAQSVLEGMAAGTFLYITFLEILPQELASSE--QRI 303
Query: 344 QQLLLLCAGIVVM 356
+++LL AG ++
Sbjct: 304 LKVILLLAGFALL 316
>gi|32490561 solute carrier family 39 (zinc transporter), member 3
isoform a [Homo sapiens]
Length = 314
Score = 40.8 bits (94), Expect = 0.002
Identities = 52/206 (25%), Positives = 82/206 (39%), Gaps = 12/206 (5%)
Query: 159 ILTFLALEKMFLDSKEEGTSQAPNKDPTAAAAALNG--GHCLAQPAAEPGLGAVVRSIKV 216
ILTF + F+D + D + + G GH L G V+ +
Sbjct: 105 ILTFRKEKPSFIDLETFNAGSDVGSDSEYESPFMGGARGHALYVEPHGHGPSLSVQGLSR 164
Query: 217 SGYLNLLANTIDNFTH----GLAVAASFLVSKKIGLLTTMAILLHEIPHEVGDFAILLRA 272
+ + LL+ H GLA+ K + L +A+ HE V + R+
Sbjct: 165 ASPVRLLSLAFALSAHSVFEGLALGLQEEGEKVVSLFVGVAV--HETLVAVALGISMARS 222
Query: 273 GFDRWSAAKLQLSTALGGLLGAGFAICTQSPKGVEETAAWVL--PFTSGGFLYIALVNVL 330
AAKL ++ + LG G + +S +GV + A VL G FL+I + +L
Sbjct: 223 AMPLRDAAKLAVTVSAMIPLGIGLGLGIESAQGVPGSVASVLLQGLAGGTFLFITFLEIL 282
Query: 331 PDLLEEEDPWRSLQQLLLLCAGIVVM 356
LEE+ L ++L L G V+
Sbjct: 283 AKELEEKSD--RLLKVLFLVLGYTVL 306
>gi|169163921 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 127
Score = 34.3 bits (77), Expect = 0.18
Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 18/131 (13%)
Query: 20 TALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVG 79
T L L++ G Q L R T TA R ++ S RL W+C G
Sbjct: 6 TFLPLKVQEERGNPQVELTMR-TVTALRGKSRNQPSSFLYQEDWRLQPWLC--------G 56
Query: 80 LSGVFPLLVIPLEMGTMLRSEA-GAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP 138
S L + + T L+ G+WR K L + GN P+ + CS+SP
Sbjct: 57 AS-----LALSSDCPTWLQVRVRGSWRWKMQLGELTRQVSGNSLNKRTPD---HACSSSP 108
Query: 139 GGEGQSLQQQQ 149
G SL +Q
Sbjct: 109 GATSTSLSMEQ 119
>gi|88954747 PREDICTED: hypothetical protein isoform 7 [Homo
sapiens]
Length = 127
Score = 34.3 bits (77), Expect = 0.18
Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 18/131 (13%)
Query: 20 TALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVG 79
T L L++ G Q L R T TA R ++ S RL W+C G
Sbjct: 6 TFLPLKVQEERGNPQVELTMR-TVTALRGKSRNQPSSFLYQEDWRLQPWLC--------G 56
Query: 80 LSGVFPLLVIPLEMGTMLRSEA-GAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP 138
S L + + T L+ G+WR K L + GN P+ + CS+SP
Sbjct: 57 AS-----LALSSDCPTWLQVRVRGSWRWKMQLGELTRQVSGNSLNKRTPD---HACSSSP 108
Query: 139 GGEGQSLQQQQ 149
G SL +Q
Sbjct: 109 GATSTSLSMEQ 119
>gi|41190403 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 127
Score = 34.3 bits (77), Expect = 0.18
Identities = 37/131 (28%), Positives = 51/131 (38%), Gaps = 18/131 (13%)
Query: 20 TALALELLGRAGGSQPALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVG 79
T L L++ G Q L R T TA R ++ S RL W+C G
Sbjct: 6 TFLPLKVQEERGNPQVELTMR-TVTALRGKSRNQPSSFLYQEDWRLQPWLC--------G 56
Query: 80 LSGVFPLLVIPLEMGTMLRSEA-GAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASP 138
S L + + T L+ G+WR K L + GN P+ + CS+SP
Sbjct: 57 AS-----LALSSDCPTWLQVRVRGSWRWKMQLGELTRQVSGNSLNKRTPD---HACSSSP 108
Query: 139 GGEGQSLQQQQ 149
G SL +Q
Sbjct: 109 GATSTSLSMEQ 119
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,403,350
Number of Sequences: 37866
Number of extensions: 629991
Number of successful extensions: 1817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1747
Number of HSP's gapped (non-prelim): 65
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.