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Search of human proteins with 40254978
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
(594 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 1228 0.0
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 1177 0.0
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 1036 0.0
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 93 6e-19
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 92 1e-18
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 87 6e-17
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 84 3e-16
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 84 4e-16
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 83 8e-16
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 82 1e-15
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 78 3e-14
gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens] 77 4e-14
gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens] 77 4e-14
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 77 6e-14
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 76 1e-13
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 75 1e-13
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 75 1e-13
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 72 1e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 71 2e-12
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 71 2e-12
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 71 3e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 70 4e-12
gi|7662018 PHD finger protein 3 [Homo sapiens] 70 4e-12
gi|146134388 YLP motif containing 1 [Homo sapiens] 68 2e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 67 6e-11
gi|52426743 cisplatin resistance-associated overexpressed protei... 67 6e-11
gi|19923485 cisplatin resistance-associated overexpressed protei... 67 6e-11
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 66 8e-11
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 66 1e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 66 1e-10
>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
Length = 594
Score = 1228 bits (3177), Expect = 0.0
Identities = 594/594 (100%), Positives = 594/594 (100%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 60
MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 60
Query: 61 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 120
PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
Sbjct: 61 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 120
Query: 121 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 180
NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
Sbjct: 121 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 180
Query: 181 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 240
NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR
Sbjct: 181 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 240
Query: 241 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 300
TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG
Sbjct: 241 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 300
Query: 301 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 360
RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF
Sbjct: 301 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 360
Query: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS 420
PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS
Sbjct: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS 420
Query: 421 ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE 480
ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE
Sbjct: 421 ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE 480
Query: 481 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 540
RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR
Sbjct: 481 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 540
Query: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
Sbjct: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
Length = 588
Score = 1177 bits (3044), Expect = 0.0
Identities = 579/603 (96%), Positives = 579/603 (96%), Gaps = 24/603 (3%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 60
MSAGEVERLVSELSGGTGGDEEEEWLYG DENEVERPEEENASANP
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP 45
Query: 61 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 120
PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
Sbjct: 46 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 105
Query: 121 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 180
NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
Sbjct: 106 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 165
Query: 181 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 240
NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR
Sbjct: 166 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 225
Query: 241 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 300
TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG
Sbjct: 226 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 285
Query: 301 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 360
RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF
Sbjct: 286 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 345
Query: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLI---------PPPGFPPPPGAPPPSLIPTIESG 411
PPGAPPTHLPPPPFLPPPPTVSTAPPLI PPPGFPPPPGAPPPSLIPTIESG
Sbjct: 346 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESG 405
Query: 412 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER 471
HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER
Sbjct: 406 HSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRER 465
Query: 472 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 531
DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER
Sbjct: 466 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 525
Query: 532 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 591
RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT
Sbjct: 526 RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 585
Query: 592 PAE 594
PAE
Sbjct: 586 PAE 588
>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
Length = 520
Score = 1036 bits (2678), Expect = 0.0
Identities = 520/594 (87%), Positives = 520/594 (87%), Gaps = 74/594 (12%)
Query: 1 MSAGEVERLVSELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANP 60
MSAGEVERLVSELSGGTGGDEEEEWLYG DENEVERPEEENASANP
Sbjct: 1 MSAGEVERLVSELSGGTGGDEEEEWLYG---------------DENEVERPEEENASANP 45
Query: 61 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 120
PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL
Sbjct: 46 PSGIEDETAENGVPKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNL 105
Query: 121 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 180
NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF
Sbjct: 106 NIKTGGRVYGTTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGF 165
Query: 181 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITAEDCTMEVTPGAEIQDGRFNLFKVQQGR 240
NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT VQQGR
Sbjct: 166 NEDTWKAYCEKQKRIRMGLEVIPVTSTTNKIT-----------------------VQQGR 202
Query: 241 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYG 300
TGNSEKETALPSTKAEFTSPPSLFKTGLPPSR
Sbjct: 203 TGNSEKETALPSTKAEFTSPPSLFKTGLPPSR---------------------------- 234
Query: 301 RAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 360
RLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF
Sbjct: 235 --------RLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDNNFSKPPPFF 286
Query: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS 420
PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS
Sbjct: 287 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRS 346
Query: 421 ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE 480
ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE
Sbjct: 347 ARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERE 406
Query: 481 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 540
RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR
Sbjct: 407 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 466
Query: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE
Sbjct: 467 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 520
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 93.2 bits (230), Expect = 6e-19
Identities = 52/119 (43%), Positives = 69/119 (57%), Gaps = 9/119 (7%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREY-AERGY 515
RE++RDR+RDR +ERDRDRDRER+R R+RER D N D R R + ER
Sbjct: 343 RERERDRDRDRTKERDRDRDRERDRDRDRERSSDR-------NKDRSRSREKSRDRERER 395
Query: 516 ERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
ER R + ER RER R RE+E R + + +R E +E D++ R K ++ R KE
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454
Score = 77.0 bits (188), Expect = 4e-14
Identities = 52/124 (41%), Positives = 72/124 (58%), Gaps = 25/124 (20%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
RE++R+RER+R+RER+R+R+RERER RERERER+ D++R R E E YE
Sbjct: 393 RERERERERERERERERERERERERERERERERE---------KDKKRDR-EEDEEDAYE 442
Query: 517 R---HRASREKEERHRER----RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
R R REKE ++ER RE+++TR E+E + RR K++K
Sbjct: 443 RRKLERKLREKEAAYQERLKNWEIRERKKTREYEK--------EAEREEERRREMAKEAK 494
Query: 570 RSKE 573
R KE
Sbjct: 495 RLKE 498
Score = 70.5 bits (171), Expect = 4e-12
Identities = 51/146 (34%), Positives = 76/146 (52%), Gaps = 20/146 (13%)
Query: 456 RREKDRDRERDRDRERDRDRD-RERERTRERERERDHSPTPSVFNSDEERYRYREYAERG 514
R+E +++R R+R+RER+R+R+ RERER RERERER+ ++ER R R ER
Sbjct: 302 RQEIEKER-RERERERERERERRERERERERERERE---------KEKERERER---ERD 348
Query: 515 YERHRASREKEERHRER---RHREKEETRHKS---SRSNSRRRHESEEGDSHRRHKHKKS 568
+R R +R RER R RE+ R+K SR SR R E + R + ++
Sbjct: 349 RDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERE 408
Query: 569 KRSKEGKEAGSEPAPEQESTEATPAE 594
+ + +E E E+E + E
Sbjct: 409 REREREREREREREREREKDKKRDRE 434
Score = 61.6 bits (148), Expect = 2e-09
Identities = 43/142 (30%), Positives = 73/142 (51%), Gaps = 6/142 (4%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ SK D + + E+++ ++ +E +++R RER RERERER+ + ER
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKER---RERERERERERERRERERERERERERE 336
Query: 506 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 564
+ +E ER ER R +ER R+R R R+++ R +SS N R E+ R +
Sbjct: 337 KEKE-RERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER 395
Query: 565 HKKSKRSKEGKEAGSEPAPEQE 586
++ +R +E +E E E+E
Sbjct: 396 ERERERERE-RERERERERERE 416
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/158 (23%), Positives = 66/158 (41%), Gaps = 22/158 (13%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
K W+ ++R + R+ ++E +R+ +R RE +E +R ++ D + YR
Sbjct: 462 KNWEI-----RERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGS 516
Query: 509 EYAERGYERHRASREKEERHRERRHREKEETRHK--------------SSRSNSRRRHES 554
+R +R + E +ER R+R E EE R + + RR +
Sbjct: 517 ALQKRLRDREK-EMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 555 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATP 592
+ + ++ K+ KE K EP E+E E P
Sbjct: 576 QIKQEPESEEEEEEKQEKEEKR--EEPMEEEEEPEQKP 611
Score = 39.3 bits (90), Expect = 0.010
Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 6/122 (4%)
Query: 472 DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER 531
+ + D+ +RE + RD +E+ R ER RE+E R RER
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERER 327
Query: 532 -----RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
R REKE+ R + R R R ++E D R + + + + + + + +E
Sbjct: 328 EREREREREKEKERER-ERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSRE 386
Query: 587 ST 588
+
Sbjct: 387 KS 388
Score = 37.0 bits (84), Expect = 0.051
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 2/38 (5%)
Query: 371 PPPFLPPPPTVSTAPPLIPPPGFP--PPPGAPPPSLIP 406
PP PP + PP IPPP FP PPP P +IP
Sbjct: 4 PPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIP 41
Score = 35.8 bits (81), Expect = 0.11
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 3/52 (5%)
Query: 357 PPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTI 408
PP P PP +PPP F PP V P+IP P P P L+PT+
Sbjct: 10 PPMGIPALPPG-IPPPQFPGFPPPVPPGTPMIPVPMSIMAPA--PTVLVPTV 58
Score = 29.6 bits (65), Expect = 8.2
Identities = 14/36 (38%), Positives = 18/36 (50%), Gaps = 1/36 (2%)
Query: 356 PPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPP 391
PPP FP G PP P P +P P ++ P + P
Sbjct: 22 PPPQFP-GFPPPVPPGTPMIPVPMSIMAPAPTVLVP 56
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 92.0 bits (227), Expect = 1e-18
Identities = 56/147 (38%), Positives = 80/147 (54%), Gaps = 15/147 (10%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D ++ + RE+ R+RER+R++ERDR+RDR+R+ RERERER+ + ++ER
Sbjct: 698 DREREKERELERERAREREREREKERDRERDRDRDHDRERERERER-------DREKERE 750
Query: 506 RYREYAERGYERHRASREKEERHRER-RHREKEETRHK------SSRSNSRRRHESEEGD 558
R RE ER ER R + ER RER R R+KE R + R + R + E D
Sbjct: 751 REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810
Query: 559 SHRRHKHKKSKRSKEGKEAGSEPAPEQ 585
+ R H + K K + GS P+P Q
Sbjct: 811 RNPRDGHDERKSKKRYRNEGS-PSPRQ 836
Score = 84.3 bits (207), Expect = 3e-16
Identities = 49/141 (34%), Positives = 78/141 (55%), Gaps = 12/141 (8%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ +++ D R+++R+RER+R+R+R+R+++RE ER R RERER+ D ER
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREK-----ERDRERD 728
Query: 506 RYREY-AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 564
R R++ ER ER R ++ ER RE R RE+E R + R E E + R K
Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERER------ERERERERERARERDK 782
Query: 565 HKKSKRSKEGKEAGSEPAPEQ 585
++ +R E K+ G + E+
Sbjct: 783 ERERQRDWEDKDKGRDDRREK 803
Score = 77.8 bits (190), Expect = 3e-14
Identities = 51/131 (38%), Positives = 69/131 (52%), Gaps = 17/131 (12%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R +R RERDR+RERDR+R+RERER R+RERE++ + ER R RE E
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKER---------ELERERARER-----E 716
Query: 517 RHRASREKEERHRERRH-REKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 575
R R ER R+R H RE+E R + R R R E R + ++ +R +E +
Sbjct: 717 REREKERDRERDRDRDHDRERERERER-DREKEREREREERERERERERERERERERE-R 774
Query: 576 EAGSEPAPEQE 586
E E E+E
Sbjct: 775 ERARERDKERE 785
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/154 (31%), Positives = 76/154 (49%), Gaps = 18/154 (11%)
Query: 452 DYYARREKDRDRERDRDRERDR-DRDRERERTRERERERDHSPTPSVFNSDEERYRYREY 510
D+ RE++R+R+R+++RER+R +R+RERER RERERER+ D+ER R R++
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERE-RERARERDKERERQRDW 790
Query: 511 AERGYERHRASREKEERHRERRHREKEETRHKSSR-----------SNSRRRHESEEGDS 559
++ R ++EE +R R+ + R R S RRR S + D+
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 560 HRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPA 593
+ K K S+ QES +P+
Sbjct: 851 YNSGDDKNEKH-----RLLSQVVRPQESRSLSPS 879
Score = 70.5 bits (171), Expect = 4e-12
Identities = 54/132 (40%), Positives = 68/132 (51%), Gaps = 21/132 (15%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
R E+ DR DR ER R+RDRERER RERERER+ ER R RE ER
Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERER-----------ERDRERE-KEREL 707
Query: 516 ERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 574
ER RA RE+E R REKE R + R + R R E D + + ++ +R +E
Sbjct: 708 ERERA-RERE------REREKERDRERDRDRDHDRERERERERDREKEREREREERERE- 759
Query: 575 KEAGSEPAPEQE 586
+E E E+E
Sbjct: 760 RERERERERERE 771
Score = 60.1 bits (144), Expect = 6e-09
Identities = 43/132 (32%), Positives = 69/132 (52%), Gaps = 8/132 (6%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
++WD A +KD R RDRDR R+R+R+RER++ R+ +RER+ + SV D +R R R
Sbjct: 1321 REWDRDA--DKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDSV-ERDRDRDRDR 1377
Query: 509 EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKS 568
+ E S ++ E E H E+ + S + + R + + G + KS
Sbjct: 1378 TFESSQIE----SVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKS 1433
Query: 569 KRSKEGKEAGSE 580
+R+ E EAG +
Sbjct: 1434 ERT-ESLEAGDD 1444
Score = 57.0 bits (136), Expect = 5e-08
Identities = 41/147 (27%), Positives = 66/147 (44%), Gaps = 15/147 (10%)
Query: 454 YARREKDRDRERDRDRERDRD---RDRERERTRERERERDHSPTPSVFNSDEERYRYREY 510
+ RR +RDR +R+R++ R + R ER+ R+ V + +ER R R+
Sbjct: 622 FERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERD- 680
Query: 511 AERGYERHRASREKEERHRER-----------RHREKEETRHKSSRSNSRRRHESEEGDS 559
ER +R R + ER RER R RE+E + + + R H+ E
Sbjct: 681 RERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERE 740
Query: 560 HRRHKHKKSKRSKEGKEAGSEPAPEQE 586
R + K+ +R +E +E E E+E
Sbjct: 741 RERDREKEREREREERERERERERERE 767
Score = 54.7 bits (130), Expect = 2e-07
Identities = 42/149 (28%), Positives = 63/149 (42%), Gaps = 50/149 (33%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERE------------------------------ 486
RE++R+RER+R+RER R+RD+ERER R+ E
Sbjct: 762 RERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERK 821
Query: 487 ------------------RERDHSPTPSVFNS-DEERYRYREYAERGYERHRASREKEER 527
R R+HSP +NS D++ ++R ++ + S
Sbjct: 822 SKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL 881
Query: 528 HRERRHREKEETRHKSSRSNSRRRHESEE 556
+R+ R KEE R K R S RR+E +E
Sbjct: 882 TEDRQGRWKEEDR-KPERKESSRRYEEQE 909
Score = 52.0 bits (123), Expect = 2e-06
Identities = 75/347 (21%), Positives = 129/347 (37%), Gaps = 41/347 (11%)
Query: 245 EKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDRYGRAES 304
+KE + +++ + PSL K+ P R S+ S S RK ++ D+ +++
Sbjct: 194 KKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKT 253
Query: 305 PDLR----RLPGAIDVIGQTITIS-----------RVEGRRRANENSNIQVLSERSATEV 349
+ R P I + I + R+E + R ++ +R +
Sbjct: 254 NQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRD- 312
Query: 350 DNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIE 409
KP P G H P + + + P P PS T+
Sbjct: 313 -----KPRSTSPAGQ---HHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLT 364
Query: 410 SGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDR 469
RSA +P +++ P S P S + + D+ R + DR +R
Sbjct: 365 PPLR-----RSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDH-ERTSQSHDRRHERRE 418
Query: 470 ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHR 529
+ RDRE++ ERE E+D S + + E R G +R R +R+ +R
Sbjct: 419 DTRGKRDREKDSREEREYEQDQSSSRDHRDDREPR--------DGRDR-RDARDTRDRRE 469
Query: 530 ERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
R R+ ++R R SR ES + R + R +EG++
Sbjct: 470 LRDSRDMRDSR--EMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRD 514
Score = 49.7 bits (117), Expect = 8e-06
Identities = 40/149 (26%), Positives = 62/149 (41%), Gaps = 7/149 (4%)
Query: 441 WPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS 500
WP D + + RE+D+ R+ DR+RER ER+R R+R+R + S SV
Sbjct: 1331 WPRNRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESV--- 1387
Query: 501 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSH 560
+R + E + SR+ +ER ++ + + S R E GD
Sbjct: 1388 --KRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLEAGDDE 1445
Query: 561 RRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ S S G+ G EP + E E
Sbjct: 1446 SKLDDAHSLGSGAGE--GYEPISDDELDE 1472
Score = 47.8 bits (112), Expect = 3e-05
Identities = 45/184 (24%), Positives = 74/184 (40%), Gaps = 26/184 (14%)
Query: 432 PHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRD-RERDRDRDRERERTRERERE-- 488
P P P P + K++ + KDR E+ RD ++R RD +R+RE+ R++ R
Sbjct: 261 PRTPSPPPPIPEDIALGKKYKE-KYKVKDRIEEKTRDGKDRGRDFERQREK-RDKPRSTS 318
Query: 489 ---RDHSPTPSVFNSDEERY-----------RYREYAERGYER------HRASREKEERH 528
+ HSP S +S + R + Y+R R++
Sbjct: 319 PAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHS 378
Query: 529 RERRHREKEETRHKSS-RSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 587
R++ RH+S R R HE RRH+ ++ R K +E S E E
Sbjct: 379 LSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQ 438
Query: 588 TEAT 591
+++
Sbjct: 439 DQSS 442
Score = 39.7 bits (91), Expect = 0.008
Identities = 42/140 (30%), Positives = 60/140 (42%), Gaps = 17/140 (12%)
Query: 452 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSD--EERYRYRE 509
D R E R DR R R + E +R+ HS + S + D +ER RY
Sbjct: 1252 DQLKRGEPSRSTSSDRQDSRSHS---SRRSSPESDRQV-HSRSGSFDSRDRLQERDRYEH 1307
Query: 510 YAERGYERHRASREKE---------ERHRER-RHREKEETRHKSSRSNSRRRHESEEGDS 559
ER ER R +R++E R+R+R R RE+E R + R + R E DS
Sbjct: 1308 DRERERER-RDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRDLDRERERLISDS 1366
Query: 560 HRRHKHKKSKRSKEGKEAGS 579
R + + R+ E + S
Sbjct: 1367 VERDRDRDRDRTFESSQIES 1386
Score = 31.6 bits (70), Expect = 2.2
Identities = 27/141 (19%), Positives = 56/141 (39%), Gaps = 15/141 (10%)
Query: 464 ERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASRE 523
E + R ++ DR ER+ + R E++ S + E+ E + + +
Sbjct: 883 EDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942
Query: 524 KEERHRERRHREKEETRHKSSRSNSRRRHE-------------SEEGD--SHRRHKHKKS 568
E+R R ++ + + K + +++ E SE+G S ++ + KKS
Sbjct: 943 SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002
Query: 569 KRSKEGKEAGSEPAPEQESTE 589
K K G ++E+ +
Sbjct: 1003 IEKKRKKSKGDSDISDEEAAQ 1023
Score = 30.4 bits (67), Expect = 4.8
Identities = 39/145 (26%), Positives = 57/145 (39%), Gaps = 19/145 (13%)
Query: 461 RDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRA 520
++ R R RE++ D +ERT E E E T + +SD Y E E R
Sbjct: 114 KESSRGRHREKE-DIKITKERTPESEEENVEWET-NRDDSDNGDINYDYVHELSLEMKRQ 171
Query: 521 SREKEERHRERRHREKEE------------TRHKSSRSNSRRRHESEEGDSHRRHKHKKS 568
++E E+ + EK E R K S S S R+ R+ K S
Sbjct: 172 KIQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSK---SPKRKSSPKSS 228
Query: 569 KRSKEGKE--AGSEPAPEQESTEAT 591
SK+ ++ A S P +Q+ T
Sbjct: 229 SASKKDRKTSAVSSPLLDQQRNSKT 253
Score = 30.0 bits (66), Expect = 6.3
Identities = 47/205 (22%), Positives = 77/205 (37%), Gaps = 37/205 (18%)
Query: 377 PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG 436
P T S L+PPP PP A ++ T+ + ++ S S A A P
Sbjct: 1090 PGSTPSPLSSLLPPP--PPVATATATTVPATLAATTAAAATSFSTSAITISTSATP---- 1143
Query: 437 SAPSWPSLVDTSKQWDYYARREKDRDRERDR------------DRERDRDRDRERERTRE 484
T+ + +A + R R R D + + D++R +
Sbjct: 1144 ----------TNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLG 1193
Query: 485 RERE-RDHSPTPSVFNSDEERYRYREYAERGYER--HRASREKEERHR-----ERRHREK 536
R R H+ S++ +R + + G +R H SR++E+ ER+ R
Sbjct: 1194 SNRSNRSHTSGRLRSPSNDSAHRSGD-DQSGRKRVLHSGSRDREKTKSLEITGERKSRID 1252
Query: 537 EETRHKSSRSNSRRRHESEEGDSHR 561
+ R + SRS S R +S S R
Sbjct: 1253 QLKRGEPSRSTSSDRQDSRSHSSRR 1277
>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
Length = 1337
Score = 86.7 bits (213), Expect = 6e-17
Identities = 79/253 (31%), Positives = 99/253 (39%), Gaps = 23/253 (9%)
Query: 357 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 415
PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171
Query: 416 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 465
Y S FP + N LP S+P + L RR +R +
Sbjct: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228
Query: 466 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521
D R RD R ER R+ RER R D S + SD +R R R YER R
Sbjct: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287
Query: 522 REKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR--RHKHKKSKRSKEGKEAGS 579
+ RHR+ R E +K S R S E R K + S GK+
Sbjct: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNY 347
Query: 580 EPAPEQESTEATP 592
E+E E P
Sbjct: 348 TSIKEKEPEETMP 360
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 84.3 bits (207), Expect = 3e-16
Identities = 44/151 (29%), Positives = 73/151 (48%), Gaps = 3/151 (1%)
Query: 447 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 506
T ++ D R +++DR R RDR R+R RDRE+ER R+ +RERD E
Sbjct: 71 TERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERE 130
Query: 507 YREYAERGYERHRASREKEERHRE---RRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 563
ERG +R + + ER R+ R R+ + R + + N ++ E E+ RR
Sbjct: 131 TEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRE 190
Query: 564 KHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ ++ ++ + ++ SE E+E T E
Sbjct: 191 RERQREKENKTEDRHSERGRERERERETETE 221
Score = 80.9 bits (198), Expect = 3e-15
Identities = 50/141 (35%), Positives = 75/141 (53%), Gaps = 17/141 (12%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHS-PTPSVFNSDEERYRYREY---AE 512
RE +R RER R+RER+R+R+R+RER RERERER+ T + ER R R+ E
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 513 RGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEE------------GDS 559
R + R R + ER RER R R+++ R + R R R +E ++
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRET 414
Query: 560 HRRHKHKKSKRSKEGKEAGSE 580
++ + +K + S+ G+E G E
Sbjct: 415 EKQREREKDRESERGRERGRE 435
Score = 80.9 bits (198), Expect = 3e-15
Identities = 52/155 (33%), Positives = 83/155 (53%), Gaps = 19/155 (12%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY- 507
+Q + RE++R RER+R+RER+R+R RE ER RE+ERER + D ER R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM---DRERNRQT 359
Query: 508 ----REYAERGYERHR-----ASREKEERHRER---RHREKEETRHK---SSRSNSRRRH 552
R AER ER R ++RE+EER R+R R +E+E K R ++R
Sbjct: 360 GREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRE 419
Query: 553 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 587
++ +S R + + + ++G+E E ++++
Sbjct: 420 REKDRESERGRERGREREKQKGRERDRERQTDRQA 454
Score = 79.3 bits (194), Expect = 9e-15
Identities = 49/139 (35%), Positives = 79/139 (56%), Gaps = 7/139 (5%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
+RE++R+RER+R+R+R+ +RDRE+ER R+R+R+ + + E R + ER
Sbjct: 316 KRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERER 375
Query: 516 ERHRAS-REKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
ER R S RE+EER R+R R R+KE R + +R E + R K ++S+R +E
Sbjct: 376 ERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQ----REREKDRESERGRE 431
Query: 574 -GKEAGSEPAPEQESTEAT 591
G+E + E++ T
Sbjct: 432 RGREREKQKGRERDRERQT 450
Score = 79.0 bits (193), Expect = 1e-14
Identities = 57/163 (34%), Positives = 82/163 (50%), Gaps = 27/163 (16%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERT----------------RERERERDHS 492
+Q D RE+ DRERDR RE++R+R +ERER RERER+RD +
Sbjct: 97 RQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRD-A 155
Query: 493 PTPSVFNSDEERYRYRE-YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRR 551
+D ER R E ++ ER + +E+ ER R+R K E RH S R R R
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRH-SERGRERER 214
Query: 552 HESEEGDSHR-------RHKHKKSKRSKEGKEAGSEPAPEQES 587
E ++ R R + +K++R +E K+A E A E+E+
Sbjct: 215 ERETETETERKRQTDRERDRQRKTERERE-KQAERERASERET 256
Score = 78.6 bits (192), Expect = 2e-14
Identities = 48/137 (35%), Positives = 73/137 (53%), Gaps = 7/137 (5%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
RR+K+R+R+ DR R+R +RDRE ER RER+RER+ N ER R R ER
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERER---NRKRERERER---ERER 327
Query: 516 ERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 574
ER R + E+ RER R R+ E R ++ ++ R ++E R + ++S R +E
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 575 KEAGSEPAPEQESTEAT 591
+E + ++E T
Sbjct: 388 RERDRDRDRQKERERQT 404
Score = 76.6 bits (187), Expect = 6e-14
Identities = 50/151 (33%), Positives = 77/151 (50%), Gaps = 12/151 (7%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSVFNSDE 502
+ KQ + E++ +R+++R+RERDRDRDR+R R +ERER+ D T ++
Sbjct: 241 EREKQAERERASERETERDKERERERDRDRDRDR-RQKERERQTDRKRQRRTERDRETER 299
Query: 503 ERYRYREYAERGYERHRASREKEERHRER-------RHREKEETRHKSSRSNSRRRHESE 555
+R R RE ER ER+R + ER RER R REKE R + ++ R +
Sbjct: 300 KRERQRE-RERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 556 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
G RR ++ +R +E + E+E
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERE 389
Score = 74.7 bits (182), Expect = 2e-13
Identities = 38/133 (28%), Positives = 67/133 (50%), Gaps = 5/133 (3%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D K+ + RE+ R ER+R +ER+R+++R+ R RER+RE+++ ER
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERE 213
Query: 506 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSS-----RSNSRRRHESEEGDSH 560
R RE + + RE++ + + R REK+ R ++S R R R + D
Sbjct: 214 RERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRD 273
Query: 561 RRHKHKKSKRSKE 573
RR K ++ + ++
Sbjct: 274 RRQKERERQTDRK 286
Score = 74.7 bits (182), Expect = 2e-13
Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 3/141 (2%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ +Q D R++ +RER++ ER+R +RE ER +ERERERD + ER
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 506 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKS-SRSNSRRRHESEEGDSHRRH 563
R+ +R ER R + K ER RER R RE+ R + R R R E D +
Sbjct: 283 TDRK-RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 564 KHKKSKRSKEGKEAGSEPAPE 584
+ K+ ++++ +E + E
Sbjct: 342 ERKRKRQTEMDRERNRQTGRE 362
Score = 73.9 bits (180), Expect = 4e-13
Identities = 45/136 (33%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
REK +RER +RE +RD++RERER R+R+R+R +D +R R R +R E
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERER--QTDRKRQR-RTERDRETE 298
Query: 517 RHRASREKEERHRER---RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
R R + + ER RER R RE+E R + + + R E E +R +R+++
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 574 GKEAGSEPAPEQESTE 589
G A + E
Sbjct: 359 TGREGRRQAERERERE 374
Score = 70.5 bits (171), Expect = 4e-12
Identities = 48/165 (29%), Positives = 80/165 (48%), Gaps = 24/165 (14%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRE-------------RERERD-- 490
+ +Q D +R+ +R+R+++R+RE++R RERER RE RERER+
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 491 -HSPTPSVFNSDEERYRYRE---YAERGYERHRASREKEERHRER-----RHREKEETRH 541
+ T +D ER R R+ E+ ER RAS + ER +ER R R+++ +
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 542 KSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
+ R R+R E D K ++ + + +E + E+E
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Score = 69.7 bits (169), Expect = 7e-12
Identities = 41/143 (28%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Query: 448 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDE---ER 504
+K D ++ R ++R+RER+ + E +R R +RER R+R+ ER+ + E ER
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 505 YRYREYAERGYERHRASREKE-ERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 563
+ RE ER +R R R+KE ER +R+ + + E ++ R R+R E + +R+
Sbjct: 259 DKERE-RERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKR 317
Query: 564 KHKKSKRSKEGKEAGSEPAPEQE 586
+ ++ + + ++ +E E+E
Sbjct: 318 ERERERERERERQRETERDREKE 340
Score = 67.8 bits (164), Expect = 3e-11
Identities = 38/127 (29%), Positives = 62/127 (48%), Gaps = 9/127 (7%)
Query: 456 RREKDRDRERDRDRERDRDRDRER--ERTRERERERDHSPTPSVFNSDEERYRYREYAER 513
+RE++R R+ +++RER DR+R+R ER R++ERER+ N E R R R+ +
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREK-------NRQERRERERQREKE 198
Query: 514 GYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
R S ER RER + E + ++ R R+R E + + + ++
Sbjct: 199 NKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETER 258
Query: 574 GKEAGSE 580
KE E
Sbjct: 259 DKERERE 265
Score = 64.7 bits (156), Expect = 2e-10
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 2/127 (1%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D K+ + +R+ + DRER+R R+ R ERER RERER+R + D +R
Sbjct: 336 DREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRD 395
Query: 506 RYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 564
R +E ER E+ R + + E+ RER + RE E R + ++ E + R
Sbjct: 396 RQKE-RERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQA 454
Query: 565 HKKSKRS 571
++ KRS
Sbjct: 455 GRQRKRS 461
Score = 64.3 bits (155), Expect = 3e-10
Identities = 44/133 (33%), Positives = 63/133 (47%), Gaps = 16/133 (12%)
Query: 457 REKDRDRERDR----DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAE 512
REK+R+R+R R DRER+R RE R ERERER+ + +R RE E
Sbjct: 337 REKERERKRKRQTEMDRERNRQTGREGRRQAERERERER---------ERDRQSAREREE 387
Query: 513 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
R +R R +++ ER E+ + ET + R R ESE G R + K+ R +
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDR---ESERGRERGREREKQKGRER 444
Query: 573 EGKEAGSEPAPEQ 585
+ + A Q
Sbjct: 445 DRERQTDRQAGRQ 457
Score = 63.2 bits (152), Expect = 7e-10
Identities = 46/154 (29%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Query: 446 DTSKQWDYYARREKDRDRERDRDR---------ERDRDRDRERERTRERERERDHSPTPS 496
+ ++Q RR+ +R+RER+R+R ER+RDRDR+R++ RER+ E+D
Sbjct: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE 413
Query: 497 VFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSN-------SR 549
ER + RE +ERG ER R +++ R R+R + + + RS
Sbjct: 414 T-EKQREREKDRE-SERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRT 471
Query: 550 RRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAP 583
R + D +R + + K S E +A S P
Sbjct: 472 ARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFP 505
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/163 (30%), Positives = 73/163 (44%), Gaps = 19/163 (11%)
Query: 434 LPGSAPSWPSL-VDTSKQWDYYARREKDRDRERDRD-----RERDRDRDRERERTRERER 487
+P +A +L V+ + D+ RR ++ R R ++ D D DRER R +ERER
Sbjct: 6 VPATADQLGTLWVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGD-DRERNRQKERER 64
Query: 488 ERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRS 546
R+ T +D +R R RE +RHR K +RHRER R REKE R
Sbjct: 65 RREKRQTER--ETDRKRERRRE-----KDRHR----KRDRHRERQRDREKERERQTDRER 113
Query: 547 NSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ +R E R ++ +R ++ + G Q E
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE 156
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 84.0 bits (206), Expect = 4e-16
Identities = 52/152 (34%), Positives = 82/152 (53%), Gaps = 10/152 (6%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSVFNSDE 502
D ++ D REK+R+R+++RDR+R R+R+ ERE R+RER+R T + D
Sbjct: 41 DRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDR 100
Query: 503 ERYRYREYAERGYERHR-ASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 561
+R R RE +R ER+R RE++++ R RE+E R + R R+R E D R
Sbjct: 101 DRERKRE-TDRNRERNRKGGRERDKQTERERDRERERQRQRE-RERQRQRERKRETDRER 158
Query: 562 RH----KHKKSKRSKEGKEAGSEPAPEQESTE 589
+ + +K +R KE K+ E E++ E
Sbjct: 159 QRWAEREERKKERKKERKKERKEKKKEEKRRE 190
Score = 75.5 bits (184), Expect = 1e-13
Identities = 48/138 (34%), Positives = 72/138 (52%), Gaps = 5/138 (3%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDR--DRDRERERTRERERERDHSPTPSVFNSDEE 503
D +Q + RE +R RER R RER R DR+R+++R RER+RE D + + E
Sbjct: 63 DRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN-RKGGRE 121
Query: 504 RYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRR 562
R + E ER ER R + + ER R+R R RE + R + + R++ +E R+
Sbjct: 122 RDKQTE-RERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 563 HKHKKSKRSKEGKEAGSE 580
K K+ KR ++ K E
Sbjct: 181 EKKKEEKRREDKKRKWGE 198
Score = 74.3 bits (181), Expect = 3e-13
Identities = 54/172 (31%), Positives = 80/172 (46%), Gaps = 29/172 (16%)
Query: 446 DTSKQWDYYARRE-----KDRDRERDRDRERDRDRDRERERTRERERERDHS---PTPSV 497
+T ++ D RE ++R R+RDR RERDR DRE+ER R++ER+R T
Sbjct: 16 ETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERE 75
Query: 498 FNSDEERYRYREY-----AERGYERHRASREKEERHRER---------------RHREKE 537
ER R RE ER +R R + + +R+RER R RE+E
Sbjct: 76 TERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERE 135
Query: 538 ETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
R + R R+R E D R+ ++ +R KE K+ + E++ E
Sbjct: 136 RQRQR-ERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEE 186
Score = 73.6 bits (179), Expect = 5e-13
Identities = 43/134 (32%), Positives = 65/134 (48%), Gaps = 8/134 (5%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R+++R RE DR +E +R+RDR+RER + ERE H D R R R+ +R E
Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTERENRHR------QRDRHRERDRQ-TDREKE 55
Query: 517 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR-RHKHKKSKRSKEGK 575
R R +R RER + E + + R R+R E D R R + +++ R++E
Sbjct: 56 RERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERN 115
Query: 576 EAGSEPAPEQESTE 589
G +Q E
Sbjct: 116 RKGGRERDKQTERE 129
Score = 65.1 bits (157), Expect = 2e-10
Identities = 45/136 (33%), Positives = 72/136 (52%), Gaps = 13/136 (9%)
Query: 456 RREKDRDRE--RDRDRERDRDRDRERE---RTRERERERDHSPTPSVFNSDEERYRYREY 510
+RE DR +E R+RDR+R+R+ ERE R R+R RERD + ++ER R +E
Sbjct: 8 KRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQT-----DREKERERQKE- 61
Query: 511 AERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKR 570
+R +R R + + ER RER+ + + + + R R R E D R +++K R
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETD-RNRERNRKGGR 120
Query: 571 SKEGKEAGSEPAPEQE 586
++ K+ E E+E
Sbjct: 121 ERD-KQTERERDRERE 135
Score = 50.8 bits (120), Expect = 3e-06
Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 20/107 (18%)
Query: 470 ERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHR 529
ER R+R RE +R +E ERERD R RE E ER R++ +RHR
Sbjct: 2 ERQRERKRETDRGKETERERD---------------RQRE-RENQTERENRHRQR-DRHR 44
Query: 530 ER---RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
ER REKE R K +R E+E +R + ++ +R ++
Sbjct: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Score = 32.3 bits (72), Expect = 1.3
Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 1/76 (1%)
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 575
ER R + + +R +E RE++ R + +++ RH + R + + K + K
Sbjct: 2 ERQRERKRETDRGKETE-RERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQK 60
Query: 576 EAGSEPAPEQESTEAT 591
E + E+E+ T
Sbjct: 61 ERDRQRQRERETERET 76
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 82.8 bits (203), Expect = 8e-16
Identities = 48/148 (32%), Positives = 81/148 (54%), Gaps = 11/148 (7%)
Query: 456 RREKDRDRERD--RDRERDRDRDRER--ERTRERERERDHSPTPSVFNSDEERYRYREYA 511
RR++DR+RE++ R R RDRD D+ER ER +ERER R+ S EE+ +
Sbjct: 349 RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKD 408
Query: 512 ERGYERHRASREKEERH-----RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 566
+R + + +KE++H RER+HR + +R+ RS SR + +S + K K
Sbjct: 409 DRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSK--HKNESKEK 466
Query: 567 KSKRSKEGKEAGSEPAPEQESTEATPAE 594
+KRS+ G + ++ + + E +P++
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSK 494
Score = 76.3 bits (186), Expect = 8e-14
Identities = 50/143 (34%), Positives = 71/143 (49%), Gaps = 15/143 (10%)
Query: 445 VDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEER 504
++ K+ R K+R++ER R R DR +R R R+RER R R S D +R
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR 354
Query: 505 YRYREY-----------AERGYERHRASREKEERHRERRHR-EKEETRHKSSRSNSRRRH 552
R +E ERG ER + ER +E+R R E EE +HK + + RRH
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDD--RRH 412
Query: 553 ESEEGDSHRRHKHKKSKRSKEGK 575
++ DS + KH +S RS+E K
Sbjct: 413 RDDKRDSKKEKKHSRS-RSRERK 434
Score = 62.0 bits (149), Expect = 1e-09
Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 29/144 (20%)
Query: 452 DYYARREKDRDRERDRDRER-----------------DRDRDRERERTRERERERDHSPT 494
DY R +R++ER+R RER D+D R R+ R+ ++E+ HS +
Sbjct: 369 DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRS 428
Query: 495 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 554
S R R R +R R S+EK +H+ E +E +K SRS S+ R +S
Sbjct: 429 RSRERKHRSRSRSRNAGKRSRSR---SKEKSSKHK----NESKEKSNKRSRSGSQGRTDS 481
Query: 555 EEGDSHRRH-----KHKKSKRSKE 573
E R H K +K RSKE
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKE 505
Score = 60.5 bits (145), Expect = 4e-09
Identities = 34/129 (26%), Positives = 60/129 (46%), Gaps = 12/129 (9%)
Query: 456 RREKDRDRERDR------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE 509
RR + R R+ DRE +R+++R+R +ERE++ + S+ E R
Sbjct: 274 RRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERR----- 328
Query: 510 YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
R ERHR+ +R +RR R++E + R ++ E G+ + + + +
Sbjct: 329 -RSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRE 387
Query: 570 RSKEGKEAG 578
RSKE + G
Sbjct: 388 RSKEQRSRG 396
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/159 (30%), Positives = 66/159 (41%), Gaps = 24/159 (15%)
Query: 459 KDRDRERDRD-RERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE-------- 509
K R R+ +D +E + DR ER R R R SP S S R +RE
Sbjct: 234 KTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRS-RSRSHHREGHGSSSFD 292
Query: 510 -YAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR------- 561
ER ER R RE +ER +ERR + + RS SR RH S R
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDR 352
Query: 562 -RHKHKKSKRSKE-----GKEAGSEPAPEQESTEATPAE 594
R + K+++R + KE G+E E+E + E
Sbjct: 353 DREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 7/118 (5%)
Query: 459 KDRDRERDRDRERDRDRDRERERT-RERERERDHSPTPSVFNSDEERYRYREYAERGYER 517
+ RD +RD +E+ R R RER R R R R+ + ++ E E+ +R
Sbjct: 411 RHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKR 470
Query: 518 HRAS----REKEERHRERRHREKEETRHKSSRSNSR--RRHESEEGDSHRRHKHKKSK 569
R+ + E+ ++R H +E K SRS R +R S+ D +H ++S+
Sbjct: 471 SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQ 528
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/122 (22%), Positives = 56/122 (45%), Gaps = 2/122 (1%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRER-ERERDHSPTPSVFNSDEERYRYREYAERG 514
+R+ ++++ R R R+R + R R R+R +R R S S + +E + + + + G
Sbjct: 416 KRDSKKEKKHSRSRSRER-KHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSG 474
Query: 515 YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 574
+ S EK ++ +EK R +S + +R H + S + + + +E
Sbjct: 475 SQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQES 534
Query: 575 KE 576
+E
Sbjct: 535 QE 536
Score = 47.4 bits (111), Expect = 4e-05
Identities = 33/141 (23%), Positives = 64/141 (45%), Gaps = 30/141 (21%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERE--------------RDHSPTPSVFNSD 501
+ ++D+D R RD +RD ++++ R+R RER+ R S S + +
Sbjct: 402 KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN 461
Query: 502 EERYRYREYAERGYE------------RHRASREKEE---RHRERRH-REKEETRHKSSR 545
E + + + + G + H S+EK R +ER H R+ +++ +S +
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521
Query: 546 SNSRRRHESEEGDSHRRHKHK 566
+ RR E+ ++HK+K
Sbjct: 522 HDRRRSQSIEQESQEKQHKNK 542
Score = 38.9 bits (89), Expect = 0.013
Identities = 21/78 (26%), Positives = 43/78 (55%), Gaps = 15/78 (19%)
Query: 462 DRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521
++ + R+ +++ R+R R++ER +RDHS + SD+ ++R R S
Sbjct: 483 EKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKD--QSDK------------HDRRR-S 527
Query: 522 REKEERHRERRHREKEET 539
+ E+ +E++H+ K+ET
Sbjct: 528 QSIEQESQEKQHKNKDET 545
Score = 33.9 bits (76), Expect = 0.43
Identities = 14/48 (29%), Positives = 27/48 (56%)
Query: 445 VDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHS 492
V+ SK+ ++ +EK R R R ++R RD ++++ + +R R S
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQS 529
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 82.0 bits (201), Expect = 1e-15
Identities = 53/156 (33%), Positives = 83/156 (53%), Gaps = 13/156 (8%)
Query: 447 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERD-HSPTPSVFNSDEERY 505
T + D ++K R+RERDR RER+RDRDRE+ER R+ E++RD T + D ER
Sbjct: 119 TEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDRERE 178
Query: 506 RYRE-YAERGYERHRASREKEERHRER-RHREKE-------ETRHKSSRSNSRRR---HE 553
+ +E ER +R R + ++ ER +R R R+++ ET + R RRR +
Sbjct: 179 KQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 554 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ G R + +K +R KE K+ + E++ E
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEE 274
Score = 75.9 bits (185), Expect = 1e-13
Identities = 48/139 (34%), Positives = 71/139 (51%), Gaps = 16/139 (11%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D Q + RE+DR+RE+ ++RE +RDRDR+R+ +ERER+ +D ER
Sbjct: 160 DRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQ-----------TDRERD 208
Query: 506 RYRE-YAERGYERHRASREKEERHRER---RHREKEETRHKSSRSNSRRRHESEEGDSHR 561
R R+ ER E R + +R RER R R KE R + R R++ +E R
Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRER-DRKEERKKERKKERKKER 267
Query: 562 RHKHKKSKRSKEGKEAGSE 580
+ K K+ KR ++ K E
Sbjct: 268 KEKKKEEKRREDKKRKWGE 286
Score = 69.3 bits (168), Expect = 9e-12
Identities = 43/134 (32%), Positives = 76/134 (56%), Gaps = 10/134 (7%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE-YAERG 514
R+EK+ +R RDR+++ + +RDRERE+ + RERERD + ER R RE ER
Sbjct: 104 RKEKETNRNRDREKQTEIERDREREKQKGRERERDR-------GRERERDRDREKERERQ 156
Query: 515 YERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
E+ R + + E RER R REK++ R ++ R R+R +E + + + ++++
Sbjct: 157 TEKDRDGQRETETERERDREREKQKER-ETERDRDRQRDTEKERERQTDRERDRQRKTQT 215
Query: 574 GKEAGSEPAPEQES 587
++ ++ E+E+
Sbjct: 216 ERQRETDREGERET 229
Score = 67.8 bits (164), Expect = 3e-11
Identities = 40/131 (30%), Positives = 66/131 (50%), Gaps = 11/131 (8%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
K+ + R++++ E +RDRER++ + RERER R RERERD D E+ R R
Sbjct: 105 KEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDR---------DREKERER 155
Query: 509 EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR-RHKHKK 567
+ E+ + R + + ER RER +++ ET R + + D R R + +
Sbjct: 156 Q-TEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
Query: 568 SKRSKEGKEAG 578
++R +E G
Sbjct: 215 TERQRETDREG 225
Score = 63.9 bits (154), Expect = 4e-10
Identities = 45/150 (30%), Positives = 75/150 (50%), Gaps = 14/150 (9%)
Query: 456 RREKDR-----DRERDRDRERDRDRDR-ERERTRERERERDHSPTPSVFNSDEERYRYRE 509
+RE+DR ++ERDRDR+RDR+R R E+E R R+RE+ T + + E+ + RE
Sbjct: 78 QRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQ---TEIERDREREKQKGRE 134
Query: 510 -YAERGYERHRASREKEERHR----ERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 564
+RG ER R ++ER R +R + + ET + R +++ E D R+
Sbjct: 135 RERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRD 194
Query: 565 HKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+K + + +E + + E T E
Sbjct: 195 TEKERERQTDRERDRQRKTQTERQRETDRE 224
Score = 63.2 bits (152), Expect = 7e-10
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 13/121 (10%)
Query: 457 REKDRDRERDR-DRERDRDRDRERERTR---ERERERDHSPTPSVFNSDEERYRYREYAE 512
R+++RDR R++ ++ERDRDR R+RER R E R RD + ER R RE +
Sbjct: 77 RQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEI-----ERDRERE-KQ 130
Query: 513 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
+G ER R + ER R+ REKE R + +R E+E R K K+ + +
Sbjct: 131 KGRERERDRGRERERDRD---REKERERQTEKDRDGQRETETERERDREREKQKERETER 187
Query: 573 E 573
+
Sbjct: 188 D 188
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 7/124 (5%)
Query: 471 RDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRE 530
+D D D +R+R R+R RE+ T + D +R R R E+ R+R REK+
Sbjct: 70 KDADGD-DRQRERDRVREK----TEKERDRDRKRDRERRRKEKETNRNR-DREKQTEIER 123
Query: 531 RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 590
R REK++ R + R R R + + R + +K + + E E E+E +
Sbjct: 124 DREREKQKGRER-ERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKE 182
Query: 591 TPAE 594
E
Sbjct: 183 RETE 186
>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
Length = 1374
Score = 77.8 bits (190), Expect = 3e-14
Identities = 68/211 (32%), Positives = 86/211 (40%), Gaps = 21/211 (9%)
Query: 357 PPFFPPGAPPTHLPPPPFLP-PPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSG 415
PP FPP PP P P +P PP T P ++PPP P PP PPP + + + G
Sbjct: 114 PPCFPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPP--PPPVMPQQVNYQYPPG 171
Query: 416 YDSRSARAFP------YGNVAFPHLP----GSAPSWPSLVDTSKQWDYYARREKDRDRER 465
Y S FP + N LP S+P + L RR +R +
Sbjct: 172 Y---SHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHY 228
Query: 466 DRDRERDRDRDR-ERERT---RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRAS 521
D R RD R ER R+ RER R D S + SD +R R R YER R
Sbjct: 229 DDHRHRDHSHGRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGR-TPSRHRSYERSRER 287
Query: 522 REKEERHRERRHREKEETRHKSSRSNSRRRH 552
+ RHR+ R E +K S R +
Sbjct: 288 ERERHRHRDNRRSPSLERSYKKEYKRSGRSY 318
>gi|197333879 genetic suppressor element 1 isoform 2 [Homo sapiens]
Length = 1113
Score = 77.0 bits (188), Expect = 4e-14
Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%)
Query: 366 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 422
P++L P PF P + + L + P +P P PG+ PP L P+ H SG R
Sbjct: 148 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 204
Query: 423 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 482
+ ++A H + L Q D RRE++R+RER+R+RE DR+R++ERER
Sbjct: 205 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 260
Query: 483 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 541
RE+ERE+ ++ER R +E RE+E ER RE+R REKE
Sbjct: 261 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 297
Query: 542 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 592
K+ + + R H +EE + + R+++ K+AG + P P Q P
Sbjct: 298 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 355
>gi|44955926 genetic suppressor element 1 isoform 1 [Homo sapiens]
Length = 1217
Score = 77.0 bits (188), Expect = 4e-14
Identities = 76/240 (31%), Positives = 114/240 (47%), Gaps = 45/240 (18%)
Query: 366 PTHLPPPPFLPPPPTVSTAPPL--IPPPGFP-PPPGAPPPSLIPTIESGHSSGYDSRSAR 422
P++L P PF P + + L + P +P P PG+ PP L P+ H SG R
Sbjct: 252 PSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPP-LHPSAMHLHLSGV--RYPP 308
Query: 423 AFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERT 482
+ ++A H + L Q D RRE++R+RER+R+RE DR+R++ERER
Sbjct: 309 ELSHSSLAALH----SERMSGLSAERLQMDEELRREREREREREREREADREREKERERE 364
Query: 483 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKE-ERHRERRHREKEETRH 541
RE+ERE+ ++ER R +E RE+E ER RE+R REKE
Sbjct: 365 REKEREQ-----------EKEREREKE------------RERELERQREQRAREKELLAA 401
Query: 542 KS--------SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE-PAPEQESTEATP 592
K+ + + R H +EE + + R+++ K+AG + P P Q P
Sbjct: 402 KALEPSFLPVAELHGLRGHATEE--RGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVP 459
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 76.6 bits (187), Expect = 6e-14
Identities = 51/128 (39%), Positives = 71/128 (55%), Gaps = 16/128 (12%)
Query: 454 YARREKDRDRE-RDRDRERDRDRDRERERT-RERERERDHSPTPSVFNSDEERYRYREYA 511
Y RE++R+RE R R+RER+R+RDRERER RERERER+H D+ER R +E
Sbjct: 401 YRERERERERENRQRERERERERDRERERRQREREREREH-------ERDKERQRRKE-- 451
Query: 512 ERGYERHRASREKEERHRERRHREKEETRHKSS---RSNSRRRHESEEGDSHRRHKHKKS 568
+ER RA R++++R R REKE + K RS ++E +
Sbjct: 452 --EWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQV 509
Query: 569 KRSKEGKE 576
KR+ E K+
Sbjct: 510 KRADEWKD 517
Score = 67.4 bits (163), Expect = 4e-11
Identities = 79/280 (28%), Positives = 111/280 (39%), Gaps = 68/280 (24%)
Query: 354 SKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIP------- 406
+K PF P GAPP L P P +P P I PP PPP P S
Sbjct: 255 TKADPFPPNGAPP--LGPHPLMPANPWGGPVVDEILPP---PPPEPPTESAWERGLRHAK 309
Query: 407 ------TIESGHSSGYDSR--------SARAFPYGNVAFPHLPGSAPSWPSLVDTSKQ-- 450
TI ++ + R F N F P + DT +
Sbjct: 310 EVLKKATIRKEQEPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPR--DVRDTVLEPY 367
Query: 451 ----WDYYARR-------EKDRDRERDRD-----RERDRDRDRE-RERTRERERERDHSP 493
+DY R E R + + + RER+R+R+RE R+R RERERERD
Sbjct: 368 ADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERERD--- 424
Query: 494 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHE 553
R RE +R ER R + ER +ER+ R++E R ++ R R+H
Sbjct: 425 ------------RERERRQRERERER----EHERDKERQRRKEEWERERAKRDEKDRQHR 468
Query: 554 SEEGDSHR-RHKHKKSKRSKEGKEAGSEPAPEQESTEATP 592
+ + R + K K RS + +EP P++E+ P
Sbjct: 469 DRDREKEREKEKGKPKPRSPQPPSRQAEP-PKKEAATTGP 507
Score = 60.1 bits (144), Expect = 6e-09
Identities = 41/141 (29%), Positives = 73/141 (51%), Gaps = 8/141 (5%)
Query: 456 RREKDRDRERDRDRER---DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAE 512
+RE++R+RERDR+RER +R+R+RE ER +ER+R ++ DE+ ++R+ +
Sbjct: 414 QRERERERERDRERERRQREREREREHERDKERQRRKEEWERERA-KRDEKDRQHRD-RD 471
Query: 513 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
R ER + + + R + R+ E + +++ + + + E D RR KS + K
Sbjct: 472 REKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRR---SKSPKKK 528
Query: 573 EGKEAGSEPAPEQESTEATPA 593
G A + T A+ A
Sbjct: 529 LGVSVSPSRARRRRKTSASSA 549
Score = 50.1 bits (118), Expect = 6e-06
Identities = 39/153 (25%), Positives = 69/153 (45%), Gaps = 25/153 (16%)
Query: 456 RREKDRDRERDRDRERDRDRDR-ERERTRERERERDH-------------------SPTP 495
+RE++R+RE +RD+ER R ++ ERER + E++R H SP P
Sbjct: 431 QREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSPQP 490
Query: 496 SVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE 555
++ + +E A G + RA K+ R + ++K S S +RRR ++
Sbjct: 491 PSRQAEPPK---KEAATTGPQVKRADEWKDPWRRSKSPKKKLGV--SVSPSRARRRRKTS 545
Query: 556 EGDSHRRHKHKKSKRSKEGKEAGSEPAPEQEST 588
+ + + S RS +GS + + S+
Sbjct: 546 ASSASASNSSRSSSRSSSYSGSGSSRSRSRSSS 578
Score = 45.4 bits (106), Expect = 1e-04
Identities = 91/439 (20%), Positives = 157/439 (35%), Gaps = 100/439 (22%)
Query: 235 KVQQGRTGNSEKETALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKANSSVGK 294
K +Q R + EKE K + SP PPSR + + + +T + + +
Sbjct: 463 KDRQHRDRDREKEREKEKGKPKPRSPQ-------PPSRQAEPPKKEAATTGPQVKRA-DE 514
Query: 295 WQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSERSATEVDN--- 351
W+D + R++SP + +G +++ SR RR+ + +S S RS++ +
Sbjct: 515 WKDPWRRSKSPKKK--------LGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSG 566
Query: 352 ----------------------------------NFSKPPPFFP--------------PG 363
+FS P P P
Sbjct: 567 SGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPA 626
Query: 364 APP-------THLPPPPFLPPPPTVSTAP-PLIPPPGFP------PPPGAPPPSLIPTIE 409
PP P PP PP T +TAP P PG P P PP
Sbjct: 627 PPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSG 686
Query: 410 SGHSSG--YDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDR 467
SG SG Y S+R+ +V+ SA S S + D YA R
Sbjct: 687 SGSGSGSSYSGSSSRSRSL-SVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSR 745
Query: 468 -----DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASR 522
+++ + ++ + +E +R+RD S P + + +++ +A
Sbjct: 746 SPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPP---KSAKPPAGGKSSQQPSTPQQAPP 802
Query: 523 EKEERHRERRHRE-KEETRHKSSRSNSRRRHESEEGDSH-----RRHKHKKSKRSKEGKE 576
+ ++ H+E K +K++ SR+R+E + D +R + S++ K
Sbjct: 803 GQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKS 862
Query: 577 AG--SEPAPEQESTEATPA 593
G P PE++ + + A
Sbjct: 863 GGRLGSPKPERQRGQNSKA 881
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 75.9 bits (185), Expect = 1e-13
Identities = 51/155 (32%), Positives = 76/155 (49%), Gaps = 21/155 (13%)
Query: 446 DTSKQWDYYARREKDRDRERD----------RDRERDRDRDRERERTRERERERD-HSPT 494
+ +Q D RE+DRDRER+ R+RERDRDR RE ER R++ERE D H+ T
Sbjct: 45 ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104
Query: 495 PSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 554
D ER + + ER ER R ++++ R + ET + R R R
Sbjct: 105 ------DRERQKQK---EREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETG 155
Query: 555 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
E + RH+ ++ +R +E +E E + T+
Sbjct: 156 RERKTEDRHRERERERKRE-RERKRETKERERHTD 189
Score = 73.2 bits (178), Expect = 6e-13
Identities = 49/152 (32%), Positives = 76/152 (50%), Gaps = 12/152 (7%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ +++ D REK DRE +R RER+RDRDR+RE RER++ER+ T +D ER
Sbjct: 53 ERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERE---TDRHTETDRERQ 109
Query: 506 RYREYA-ERGYERHRASREKEERHRER-----RHREKEETRHKSSRSNSRRRHESEEGDS 559
+ +E ER +R R +++ R R+ R RE++ R R R R +
Sbjct: 110 KQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAER---ERETGRERKTEDRHRE 166
Query: 560 HRRHKHKKSKRSKEGKEAGSEPAPEQESTEAT 591
R + ++ +R +E KE E+E T
Sbjct: 167 RERERKRERERKRETKERERHTDMERERQRET 198
Score = 72.0 bits (175), Expect = 1e-12
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 13/145 (8%)
Query: 456 RREKDRDRER-------DRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
RRE DR+R+R DR ERDR RDRER R R+R+RER+ T ER R R
Sbjct: 24 RRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDRERE-KQTDREGERQRERERDR 82
Query: 509 EYAERGYERHRASREKEERH----RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHK 564
+ +R ER R + +RH RER+ +++ E R +++ E + R
Sbjct: 83 D-RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141
Query: 565 HKKSKRSKEGKEAGSEPAPEQESTE 589
++ ++++ +E G E E E
Sbjct: 142 RERERQAERERETGRERKTEDRHRE 166
Score = 67.8 bits (164), Expect = 3e-11
Identities = 48/156 (30%), Positives = 73/156 (46%), Gaps = 32/156 (20%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERE------------------------R 481
+ KQ D R+++R+R+RDR RE +R+RD+ERE R
Sbjct: 63 EREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDR 122
Query: 482 TRERERERDHSPTPSVFNSDEERYRYRE-YAERGYERHRASREKEERHRERRHREKEETR 540
RE+++E +D E R RE AER E R R+ E+RHRE R RE++ R
Sbjct: 123 EREKQKEMGRER-----QTDRETDRERERQAERERETGR-ERKTEDRHRE-RERERKRER 175
Query: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
+ + R RH E + R K+ ++ + +E
Sbjct: 176 ERKRETKERERHTDMERERQRETDRKRDRQRESERE 211
Score = 63.2 bits (152), Expect = 7e-10
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 4/113 (3%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D +Q E+ RDRER++ +E R+R +RE RERER+ + E+R+
Sbjct: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164
Query: 506 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGD 558
R RE ER ER R++E + RER + E + ++ R R+R E D
Sbjct: 165 RERE-RERKRER---ERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
Score = 62.4 bits (150), Expect = 1e-09
Identities = 43/134 (32%), Positives = 68/134 (50%), Gaps = 17/134 (12%)
Query: 462 DRERDRDRERDRDRDRERE-----RTRERERERDHSPTPSVFNSDEERYRYRE-YAERGY 515
DR+R+R RE DR+RDR +E R ER+R+RD N + +R R RE +R
Sbjct: 18 DRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER-----NRERDRDREREKQTDREG 72
Query: 516 ERHRASREKEERHRE---RRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
ER R +R RE R +E+E RH + R R + +E + R ++ K+ +
Sbjct: 73 ERQRERERDRDRQRETERERDKERETDRHTET---DRERQKQKEREMERVRDREREKQKE 129
Query: 573 EGKEAGSEPAPEQE 586
G+E ++ ++E
Sbjct: 130 MGRERQTDRETDRE 143
Score = 30.4 bits (67), Expect = 4.8
Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 1/64 (1%)
Query: 523 EKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPA 582
E +R RERR RE + R ++ S + RH + R ++ + + K+ E
Sbjct: 15 ETMDRQRERR-RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGE 73
Query: 583 PEQE 586
++E
Sbjct: 74 RQRE 77
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 75.5 bits (184), Expect = 1e-13
Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 27/153 (17%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D ++ D +EKDR+RER+++ E+DRD+++E+E+ +E+ERE+D S DE+R
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRK 472
Query: 506 RYRE--YAERGYERHRASREKEERHRERRHREKEET-------RHKSSRSNS-------- 548
+ ++ R Y R SR R RR R + + KSSRS S
Sbjct: 473 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 532
Query: 549 -----RRRHESEEGDSHRRHKHKKSKRSKEGKE 576
R H SE + R +KS ++GKE
Sbjct: 533 KKREKERDHISERRERERSTSMRKSSNDRDGKE 565
Score = 68.2 bits (165), Expect = 2e-11
Identities = 39/143 (27%), Positives = 77/143 (53%), Gaps = 14/143 (9%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R K++DRE++R+RE++R++++ER + ++R++ER+ D ER R +E+ E+ +
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEH-EKDRD 446
Query: 517 RHRASREKEERHRER-RHREKEETRHKSSRS-------NSRRRHESEEGDSHRRHKHKKS 568
+ + + +E+ RE+ R +E +E R K +S N+ RR S + RR S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 569 KRSKEGK----EAGSEPAPEQES 587
+ + K ++ P+P +
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRN 529
Score = 67.4 bits (163), Expect = 4e-11
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 18/145 (12%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+ KDRD+ER++DRE+D+++DRERER E+E E+D D+E+ R ++ ++ E
Sbjct: 413 KNKDRDKEREKDREKDKEKDRERER--EKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDE 469
Query: 517 R-------------HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 563
+ + ASR RERR R + + +S R++ + +S S R
Sbjct: 470 KRKKDKKSRTPPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSR 528
Query: 564 KHKKSKRSKEGKEAGSEPAPEQEST 588
K KR KE ++ SE + ST
Sbjct: 529 NKKDKKREKE-RDHISERRERERST 552
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/146 (26%), Positives = 74/146 (50%), Gaps = 21/146 (14%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+EKDR++ER+R++ER+++++R + + R++ERE+D + +++R R RE +
Sbjct: 391 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-----DKEKDRERERE------K 439
Query: 517 RHRASREKEERHRERRHREKEETR----------HKSSRSNSRRRHESEEGDSHRRHKHK 566
H R+KE+ + + +E+E+ R K SR+ R + S S R + +
Sbjct: 440 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 499
Query: 567 KSKRSKEGKEAGSEPAPEQESTEATP 592
+ RS S+ + S +P
Sbjct: 500 RRSRSSSRSPRTSKTIKRKSSRSPSP 525
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/114 (31%), Positives = 68/114 (59%), Gaps = 11/114 (9%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
+R+ R++ ++++R +++DR++ERER +ERE+E++ N D ++ R ++ E+
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKD-REKDK 429
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
E+ R RE+E+ H + R +EKE+ + K R E +E +R K KKS+
Sbjct: 430 EKDR-EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE----KRKKDKKSR 478
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+ K R R +R R R +DR R + ++R + R+ + S +S ++R RE +
Sbjct: 330 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 389
Query: 517 RHRASREKEERHRERRHREKEETRHK---SSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
REKE + R +EKE ++K R R + + ++ + R +H+K + ++
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449
Query: 574 GKEAGSEPAPEQESTE 589
KE E E++ ++
Sbjct: 450 EKEQDKEKEREKDRSK 465
Score = 61.2 bits (147), Expect = 3e-09
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 30/162 (18%)
Query: 458 EKDRDRERDR--DRERDRDRDRERERTRERERERDHSPTPSVFN-------SDEERYRYR 508
EKDRD+E+++ D+E++R++DR +E +R++++ P +N S ER R R
Sbjct: 442 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 501
Query: 509 EYAE--------------------RGYERHRASREKEERH-RERRHREKEETRHKSSRSN 547
+ R + REKE H ERR RE+ + KSS
Sbjct: 502 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Query: 548 SRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ + S + +H K S KE + AP E +
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 603
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/133 (23%), Positives = 58/133 (43%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R + +DR R + + R + RER ++R R RD ++ER + ++ +
Sbjct: 342 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 401
Query: 517 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
+EKE + R +E+E+ R K + R E E + K K+ + KE ++
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461
Query: 577 AGSEPAPEQESTE 589
S+ E+ +
Sbjct: 462 DRSKEIDEKRKKD 474
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 454 YARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER 513
+ +R K R+R + R R RD+ R+ TRE+ +E++ V D E+ R RE ER
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKER-----VKEKDREKERERE-KER 405
Query: 514 GYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
E+ R + ++ RE+ R ++KE+ R + + + E+ + K ++ RSK
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465
Query: 573 E 573
E
Sbjct: 466 E 466
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 75.5 bits (184), Expect = 1e-13
Identities = 49/153 (32%), Positives = 75/153 (49%), Gaps = 27/153 (17%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D ++ D +EKDR+RER+++ E+DRD+++E+E+ +E+ERE+D S DE+R
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK-----EIDEKRK 356
Query: 506 RYRE--YAERGYERHRASREKEERHRERRHREKEET-------RHKSSRSNS-------- 548
+ ++ R Y R SR R RR R + + KSSRS S
Sbjct: 357 KDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKD 416
Query: 549 -----RRRHESEEGDSHRRHKHKKSKRSKEGKE 576
R H SE + R +KS ++GKE
Sbjct: 417 KKREKERDHISERRERERSTSMRKSSNDRDGKE 449
Score = 68.2 bits (165), Expect = 2e-11
Identities = 39/143 (27%), Positives = 77/143 (53%), Gaps = 14/143 (9%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R K++DRE++R+RE++R++++ER + ++R++ER+ D ER R +E+ E+ +
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-EKDREREREKEH-EKDRD 330
Query: 517 RHRASREKEERHRER-RHREKEETRHKSSRS-------NSRRRHESEEGDSHRRHKHKKS 568
+ + + +E+ RE+ R +E +E R K +S N+ RR S + RR S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 569 KRSKEGK----EAGSEPAPEQES 587
+ + K ++ P+P +
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRN 413
Score = 67.4 bits (163), Expect = 4e-11
Identities = 46/145 (31%), Positives = 74/145 (51%), Gaps = 18/145 (12%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+ KDRD+ER++DRE+D+++DRERER E+E E+D D+E+ R ++ ++ E
Sbjct: 297 KNKDRDKEREKDREKDKEKDRERER--EKEHEKDRDKEKEK-EQDKEKEREKDRSKEIDE 353
Query: 517 R-------------HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 563
+ + ASR RERR R + + +S R++ + +S S R
Sbjct: 354 KRKKDKKSRTPPRSYNASRRSRSSSRERR-RRRSRSSSRSPRTSKTIKRKSSRSPSPRSR 412
Query: 564 KHKKSKRSKEGKEAGSEPAPEQEST 588
K KR KE ++ SE + ST
Sbjct: 413 NKKDKKREKE-RDHISERRERERST 436
Score = 67.0 bits (162), Expect = 5e-11
Identities = 38/146 (26%), Positives = 74/146 (50%), Gaps = 21/146 (14%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+EKDR++ER+R++ER+++++R + + R++ERE+D + +++R R RE +
Sbjct: 275 KEKDREKEREREKEREKEKERGKNKDRDKEREKDREK-----DKEKDRERERE------K 323
Query: 517 RHRASREKEERHRERRHREKEETR----------HKSSRSNSRRRHESEEGDSHRRHKHK 566
H R+KE+ + + +E+E+ R K SR+ R + S S R + +
Sbjct: 324 EHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR 383
Query: 567 KSKRSKEGKEAGSEPAPEQESTEATP 592
+ RS S+ + S +P
Sbjct: 384 RRSRSSSRSPRTSKTIKRKSSRSPSP 409
Score = 65.1 bits (157), Expect = 2e-10
Identities = 36/114 (31%), Positives = 68/114 (59%), Gaps = 11/114 (9%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
+R+ R++ ++++R +++DR++ERER +ERE+E++ N D ++ R ++ E+
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGK-----NKDRDKEREKD-REKDK 313
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
E+ R RE+E+ H + R +EKE+ + K R E +E +R K KKS+
Sbjct: 314 EKDR-EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDE----KRKKDKKSR 362
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/136 (25%), Positives = 65/136 (47%), Gaps = 3/136 (2%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
+ K R R +R R R +DR R + ++R + R+ + S +S ++R RE +
Sbjct: 214 QSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKER 273
Query: 517 RHRASREKEERHRERRHREKEETRHK---SSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
REKE + R +EKE ++K R R + + ++ + R +H+K + ++
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333
Query: 574 GKEAGSEPAPEQESTE 589
KE E E++ ++
Sbjct: 334 EKEQDKEKEREKDRSK 349
Score = 61.2 bits (147), Expect = 3e-09
Identities = 43/162 (26%), Positives = 69/162 (42%), Gaps = 30/162 (18%)
Query: 458 EKDRDRERDR--DRERDRDRDRERERTRERERERDHSPTPSVFN-------SDEERYRYR 508
EKDRD+E+++ D+E++R++DR +E +R++++ P +N S ER R R
Sbjct: 326 EKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRR 385
Query: 509 EYAE--------------------RGYERHRASREKEERH-RERRHREKEETRHKSSRSN 547
+ R + REKE H ERR RE+ + KSS
Sbjct: 386 SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Query: 548 SRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ + S + +H K S KE + AP E +
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENK 487
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/133 (23%), Positives = 58/133 (43%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R + +DR R + + R + RER ++R R RD ++ER + ++ +
Sbjct: 226 RSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER 285
Query: 517 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
+EKE + R +E+E+ R K + R E E + K K+ + KE ++
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345
Query: 577 AGSEPAPEQESTE 589
S+ E+ +
Sbjct: 346 DRSKEIDEKRKKD 358
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 10/121 (8%)
Query: 454 YARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER 513
+ +R K R+R + R R RD+ R+ TRE+ +E++ V D E+ R RE ER
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDK---RKDTREKIKEKER-----VKEKDREKERERE-KER 289
Query: 514 GYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
E+ R + ++ RE+ R ++KE+ R + + + E+ + K ++ RSK
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349
Query: 573 E 573
E
Sbjct: 350 E 350
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 72.0 bits (175), Expect = 1e-12
Identities = 45/131 (34%), Positives = 71/131 (54%), Gaps = 10/131 (7%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDR------DRDRERERTRERERERDHSPTPSVFN 499
D + + RE+ RDR+R++DRER R D+DRE E ++R+RER+ T +
Sbjct: 115 DRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRD 174
Query: 500 SDEERYRYREYAERGYERHRASREKEERHRER-RHREKEETRHKSSRSNSRRRHESEEGD 558
+ ER + RE R +R R REKE+R R+R R +E+E+ R++ R R R + + +
Sbjct: 175 RERERQKQRE-TRRDRDRER-QREKEDRERDRDRQKEREKDRYR-ERETGRDRDKERDRE 231
Query: 559 SHRRHKHKKSK 569
R + K
Sbjct: 232 RQREKDRDRQK 242
Score = 71.6 bits (174), Expect = 2e-12
Identities = 44/149 (29%), Positives = 76/149 (51%), Gaps = 16/149 (10%)
Query: 446 DTSKQWDYYARREKDRDR------ERDRDRERDRDRDRERERTRERERERDHSPTPSV-- 497
D ++ D +R +DRDR +RDR+ E +R +RER+R R+RE++R+ +
Sbjct: 89 DRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGI 148
Query: 498 -----FNSDEERYRYREYAERGYERHR-ASREKEERHRERRHREKEETRHKSSRSNSRRR 551
++++R R RE E ER+R RE++++ RR R++E R K R R R
Sbjct: 149 DKDREIETEKDRDREREMGET--ERYRDRERERQKQRETRRDRDRERQREKEDRERDRDR 206
Query: 552 HESEEGDSHRRHKHKKSKRSKEGKEAGSE 580
+ E D +R + + + + +E E
Sbjct: 207 QKEREKDRYRERETGRDRDKERDRERQRE 235
Score = 69.3 bits (168), Expect = 9e-12
Identities = 43/166 (25%), Positives = 81/166 (48%), Gaps = 14/166 (8%)
Query: 434 LPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSP 493
L GS + + + +Q + +R++ ++R R++DRE ++DRDR+R+R RER+R RD
Sbjct: 47 LRGSRVAPAIIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDR 106
Query: 494 TPSVFNSDEERYRYREYAERGYERHRASREKEERHRER-------------RHREKEETR 540
+ + ER +R R + ER R+R + R++E
Sbjct: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREM 166
Query: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
++ R R R ++ ++ RR + ++ +R KE +E + E+E
Sbjct: 167 GETERYRDRERERQKQRET-RRDRDRERQREKEDRERDRDRQKERE 211
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/149 (32%), Positives = 69/149 (46%), Gaps = 24/149 (16%)
Query: 457 REKDRDRERDRDRER--------DRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
R++ RDRER R R+R DRDR+ E ER ERER+RD D ER R R
Sbjct: 90 RQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKR-----EKDRERQRQR 144
Query: 509 EY---------AERGYERHRASREKEE-RHRERRHREKEETRHKSSRSNSRRRHESEEGD 558
E E+ +R R E E R RER +++ ETR R R + + E
Sbjct: 145 EIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDR 204
Query: 559 SHRRHKHKKSKRSKE-GKEAGSEPAPEQE 586
++ + K R +E G++ E E++
Sbjct: 205 DRQKEREKDRYRERETGRDRDKERDRERQ 233
Score = 63.2 bits (152), Expect = 7e-10
Identities = 32/87 (36%), Positives = 49/87 (56%), Gaps = 1/87 (1%)
Query: 458 EKDRDRERDR-DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
EKDRDRER+ + ER RDR+RER++ RE R+RD + + +R R +E + Y
Sbjct: 157 EKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYR 216
Query: 517 RHRASREKEERHRERRHREKEETRHKS 543
R++++ R REK+ R K+
Sbjct: 217 ERETGRDRDKERDRERQREKDRDRQKA 243
Score = 62.4 bits (150), Expect = 1e-09
Identities = 41/151 (27%), Positives = 72/151 (47%), Gaps = 25/151 (16%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYRE------- 509
RE++R RER+R R+R ++R RE++R E++R+R D ER R+R+
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRK-------RDRERQRWRDRDRKRER 110
Query: 510 --------YAERGYERHRASREKEERHRERRHREK---EETRHKSSRSNSRRRHESEEGD 558
ER ER R K E+ RER+ + + ++ R + + R E E +
Sbjct: 111 WGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETE 170
Query: 559 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+R + ++ K+ + ++ E E+E E
Sbjct: 171 RYRDRERERQKQRETRRDRDRERQREKEDRE 201
Score = 47.4 bits (111), Expect = 4e-05
Identities = 23/50 (46%), Positives = 34/50 (68%), Gaps = 2/50 (4%)
Query: 446 DTSKQWDYYARREKDRDRERD--RDRERDRDRDRERERTRERERERDHSP 493
D + D REKDR RER+ RDR+++RDR+R+RE+ R+R++ D P
Sbjct: 199 DRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAIDCVP 248
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 71.2 bits (173), Expect = 2e-12
Identities = 39/154 (25%), Positives = 72/154 (46%), Gaps = 3/154 (1%)
Query: 435 PGSAPSWPSLVDTSKQWDYYARRE--KDRDRERDRDRERDRDRDRERERTRERERERDHS 492
P + P W S + ++ + R+E K+R+ ER ++R R RERE+ R+RER +
Sbjct: 28 PCTQPGWQSEI-REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 493 PTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRH 552
E + R RE + E ++KE++ R R +E +E K R R+
Sbjct: 87 KGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKE 146
Query: 553 ESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
+ + + + +K ++ +E K+ G + +E
Sbjct: 147 RERKKEEREKERERKERKKRERKQVGEKEEERKE 180
Score = 66.6 bits (161), Expect = 6e-11
Identities = 37/130 (28%), Positives = 65/130 (50%), Gaps = 9/130 (6%)
Query: 448 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY 507
+K+ + +R+K +ER R + ++R+R+ ER RE +ER+ EER +
Sbjct: 106 NKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE--------RKKEEREKE 157
Query: 508 REYAERGYERHRASREKEERHRERRHRE-KEETRHKSSRSNSRRRHESEEGDSHRRHKHK 566
RE ER + EKEE +E+ +E K+ R++ R R R E E R+ K +
Sbjct: 158 RERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEE 217
Query: 567 KSKRSKEGKE 576
+ K ++ ++
Sbjct: 218 RKKERQKDRQ 227
Score = 66.2 bits (160), Expect = 8e-11
Identities = 39/120 (32%), Positives = 63/120 (52%), Gaps = 3/120 (2%)
Query: 455 ARREKDRDRERDRDRERDRDRDRER-ERTRERER-ERDHSPTPSVFNSDEERYRYREYAE 512
++ K+R+R+ +R RE ++R+R++ ER +ERER ER V +EER
Sbjct: 127 SKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKER 186
Query: 513 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
+ ER+R R+KE +ERR R+KE + K R R++ R K ++ +R K
Sbjct: 187 KKRERNRKERKKERERKERRERKKER-KKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 63.2 bits (152), Expect = 7e-10
Identities = 38/126 (30%), Positives = 60/126 (47%), Gaps = 4/126 (3%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
++E+ R + ++RER +R RE + RER++E ER + E E
Sbjct: 120 KKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERK 179
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE-G 574
E+ R R+K ER+R+ R +E+E K R + R + EE R+ + + R KE G
Sbjct: 180 EKERKERKKRERNRKERKKERE---RKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 575 KEAGSE 580
K E
Sbjct: 237 KRERKE 242
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 12/105 (11%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ K+ + R++++R + +++ ER +ER++ +ER +ER
Sbjct: 153 EREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER-----------KKERE 201
Query: 506 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRR 550
R +E ER ER + K+ER ++R+ +E+ R K R ++
Sbjct: 202 R-KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 71.2 bits (173), Expect = 2e-12
Identities = 73/255 (28%), Positives = 100/255 (39%), Gaps = 37/255 (14%)
Query: 345 SATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPP------PG 398
SA + N P F G P + P P PL+ P PP
Sbjct: 1995 SAPFSEKNEQTPSRFHFQGQAPQVMKPGP-----------RPLLELPSHPPQHRKDRWEE 2043
Query: 399 APPPSLIPTIESGHS-------SGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQW 451
A PPS + + G + D R + Y N F ++
Sbjct: 2044 AGPPSALSSSAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEP 2103
Query: 452 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYA 511
D R +DR RER+R R R+RD +R R +R R++D S D +R R R A
Sbjct: 2104 DAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSS-------RDWDRNRERS-A 2155
Query: 512 ERGYERHRASREKEERHRER-RHREKEETRHKS-SRSNSRRRHESEEGDSHRRHKHKKSK 569
R ER ++ +R RER R+RE+E R + RS SR R + D R K
Sbjct: 2156 NRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRS 2215
Query: 570 RSKEGKEAGSEPAPE 584
+S KE+ +P PE
Sbjct: 2216 KS---KESARDPKPE 2227
Score = 64.7 bits (156), Expect = 2e-10
Identities = 38/109 (34%), Positives = 54/109 (49%), Gaps = 16/109 (14%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
D+S+ WD R +RDRER+ DR ++ DR RER R RERER+R D +R
Sbjct: 2142 DSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDR---------RRDRDRS 2192
Query: 506 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 554
R R ER R ER R+R+ R K + + + + R ++
Sbjct: 2193 RSR-------ERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDA 2234
Score = 53.1 bits (126), Expect = 7e-07
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 9/113 (7%)
Query: 449 KQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYR 508
+ WD ++ RD++ RD +R+R+R R+R RE +R ++ ++ ER R R
Sbjct: 2127 RDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKE-------WDRSRERSRNR 2179
Query: 509 EYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 561
E ER R R ER R++ R++E R + RS S+ + ++ R
Sbjct: 2180 E-RERDRRRDRDRSRSRERDRDKA-RDRERGRDRKDRSKSKESARDPKPEASR 2230
Score = 40.4 bits (93), Expect = 0.005
Identities = 45/177 (25%), Positives = 65/177 (36%), Gaps = 39/177 (22%)
Query: 361 PPGAPPTHLPPPPFLPPPP---TVSTAPPLIPPPGFPPPPGAPPPSLIPTIES------- 410
PPG+PP PPP LP PP +S+ P P P A + + S
Sbjct: 1257 PPGSPP----PPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAASSTASSASKTAS 1312
Query: 411 ----------GHSSGYDSRSARAFPYGNVAFPHLP-----GSAPSWPSLVDTSKQWDYYA 455
G +D SAR P P P P+ P L +Q+ ++
Sbjct: 1313 PLEHILQTLFGKKKSFDP-SAREPPGSTAGLPQEPKTTAEDGVPAPPLLDPIVQQFGQFS 1371
Query: 456 RREKDRDRERDRDRERDRDRDRER-------ERTRERERERDHSPTPSVFNSDEERY 505
+ + + E DR + + + D ER ER R E ER +P + +E Y
Sbjct: 1372 KDKALEEEEDDRPYDPEEEYDPERAFDTQLVERGRRHEVER--APEAAAAEREEVAY 1426
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo
sapiens]
Length = 1792
Score = 70.9 bits (172), Expect = 3e-12
Identities = 70/273 (25%), Positives = 103/273 (37%), Gaps = 47/273 (17%)
Query: 342 SERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPP--PPGA 399
SERS + P F P +PPPP PPPP PP +PPP F P PPG
Sbjct: 539 SERSQRTQGPSLPATPVFVP-------VPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQ 591
Query: 400 PPPSLIPTIESGHSSGYDSRSARAFP--YGNVAFPHLPGSAPSWPSLVDTSKQWDYYARR 457
PPP +GY S FP N++ P + + S + Q +R
Sbjct: 592 PPP-----------AGY-SVPPPGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSRE 639
Query: 458 EKDRDRERDRDRERDRDRDRE------------RERTRERERERDHSPTP---SVFNSDE 502
E R++ R ++ E+ + + E ++ +ER R S +P S ++
Sbjct: 640 EFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSS 699
Query: 503 ERY--------RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES 554
Y R R Y+ R + R + RR R K SRS+ R S
Sbjct: 700 YTYSKSRSGSTRSRSYS-RSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRS 758
Query: 555 EEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 587
R H +S ++ G+ P+ E+
Sbjct: 759 RSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGET 791
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 487 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE-TRHKSSR 545
R + HS +PSV S + R + +S E ++ ++++ +EK++ +HK +
Sbjct: 1689 RNQSHS-SPSV--SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHK 1745
Query: 546 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 590
+ + E + ++HKHKK K+SK+ K+ E + + ++
Sbjct: 1746 KHKKHAGTEVELEKSQKHKHKK-KKSKKNKDKEKEKEKDDQKVKS 1789
Score = 34.3 bits (77), Expect = 0.33
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 453 YYARREKDRDR-ERDRDRERDRDRDRERER----------TRERERERDHSPTP----SV 497
YY R RD E++R RE +R E+ R + SP ++
Sbjct: 811 YYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNI 870
Query: 498 FNSDEERYRYREYAERGYERHRA----SREKEERHRERRHREKEETRHKSSRSNSRRRHE 553
NS R R +Y G + HR+ S E+ H +K+ T+ K S E
Sbjct: 871 RNSPFTRGRREDYV--GGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKES------E 922
Query: 554 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ GD + +KHKK ++ ++G+E+ PE T E
Sbjct: 923 NAPGDG-KGNKHKKHRKRRKGEESEGFLNPELLETSRKSRE 962
Score = 33.5 bits (75), Expect = 0.57
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 21/95 (22%)
Query: 479 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE 538
R + + R HS + S S + S++K+++ +++H K+
Sbjct: 1702 RSHSPSGSQTRSHSSSASSAESQD------------------SKKKKKKKEKKKH--KKH 1741
Query: 539 TRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
+HK + ++ E E+ H +HK KKSK++K+
Sbjct: 1742 KKHKKHKKHAGTEVELEKSQKH-KHKKKKSKKNKD 1775
Score = 30.8 bits (68), Expect = 3.7
Identities = 29/154 (18%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Query: 447 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 506
T ++ D A +K+ + + + D +RER E ++ TP N+
Sbjct: 1019 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1078
Query: 507 YREYAERGYERHRASREKEERHRERRHREKEETRH------KSSRSNSRRRHESEEGDSH 560
++ G R S+ +E H+E + ++E+ + KS + ++ + + +
Sbjct: 1079 QKDEKITGTPRKAHSKSAKE-HQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN 1137
Query: 561 RRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ +K KR ++ +E G + E S + + E
Sbjct: 1138 KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLE 1171
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 70.5 bits (171), Expect = 4e-12
Identities = 46/149 (30%), Positives = 75/149 (50%), Gaps = 16/149 (10%)
Query: 456 RREKDRDRERDRDRERDRDRD-------RERERTRERERERDHSPTPSVFNSDEER---- 504
RRE+++ R+R+R++ER R+R ++RER +ERER+R ++ER
Sbjct: 40 RREREK-RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRK 98
Query: 505 --YRYREYAERGYERHRASREKEERHRERRHR--EKEETRHKSSRSNSRRRHESEEGDSH 560
+ RE +RG + +E++ER RE + R K + R K R R+R +
Sbjct: 99 KEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRER 158
Query: 561 RRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
+R K KK +R K+ + E E+E E
Sbjct: 159 KRKKRKKEEREKKRERNRKERKKERERKE 187
Score = 68.9 bits (167), Expect = 1e-11
Identities = 35/122 (28%), Positives = 65/122 (53%), Gaps = 1/122 (0%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERER-ERDHSPTPSVFNSDEERYRYREYAERG 514
RREK+R + + ++R+R + RER +++ER ER+ ++R + + ER
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERK 148
Query: 515 YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEG 574
E+ R RE++ + R++ REK+ R++ R R R E E R+ + +K K K+
Sbjct: 149 REKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Query: 575 KE 576
++
Sbjct: 209 RK 210
Score = 67.4 bits (163), Expect = 4e-11
Identities = 43/122 (35%), Positives = 66/122 (54%), Gaps = 6/122 (4%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAER-- 513
+RE +R +ER R+RE+ R R+RE+ER RER ++ + ER R +R
Sbjct: 31 QRESERKKER-REREK-RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKE 88
Query: 514 GYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
E+ R R+KE++ RER+ R + E + K R R E+++ +R K +K KR KE
Sbjct: 89 RREKERRKRKKEKKKRERKQRGRRERKKKKER--KERERENKQRRERKRKKRRKKKRRKE 146
Query: 574 GK 575
K
Sbjct: 147 RK 148
Score = 65.5 bits (158), Expect = 1e-10
Identities = 36/137 (26%), Positives = 66/137 (48%), Gaps = 4/137 (2%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
REK R R+++R + + ++RER + RER + ++ R R+ +R +
Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141
Query: 517 RHRASREKEE----RHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
+ R R++E+ R R+R+ R+KEE K R+ R+ E E + R K +K +R K
Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 573 EGKEAGSEPAPEQESTE 589
+ + Q ++
Sbjct: 202 KKERKKDRKTDRQTDSQ 218
Score = 63.9 bits (154), Expect = 4e-10
Identities = 41/125 (32%), Positives = 65/125 (52%), Gaps = 17/125 (13%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
RRE+ + +ER ++RER+ + RER+R + R+++R +ER R +E +R
Sbjct: 111 RRERKKKKER-KERERENKQRRERKRKKRRKKKRR-----------KERKREKERGKR-- 156
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 575
ER R R+KEER ++R KE K R RR +E RR K ++ K K +
Sbjct: 157 ERKRKKRKKEEREKKRERNRKE---RKKERERKERRERKKERKKERRKKKERKKDRKTDR 213
Query: 576 EAGSE 580
+ S+
Sbjct: 214 QTDSQ 218
Score = 60.8 bits (146), Expect = 3e-09
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 467 RDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEE 526
R+ ER ++R +R RERE+ER ++R R +E + ER + +E+ E
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 527 RHRERRHREKEETRHKS----SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
+ R +R +EK++ K R + R E E + RR + +K +R K+ ++
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Score = 58.2 bits (139), Expect = 2e-08
Identities = 32/120 (26%), Positives = 57/120 (47%), Gaps = 9/120 (7%)
Query: 470 ERDRDRDRE------RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASRE 523
+R+ +R +E R+R RE+ER+R+ ER + RE + E+ R R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 524 KEERHRERRHREKEETRHKSSRSNSRRRHESE---EGDSHRRHKHKKSKRSKEGKEAGSE 580
++ER + ++ ++K E + + R +++ E E R K KK ++ K KE E
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Score = 37.0 bits (84), Expect = 0.051
Identities = 16/56 (28%), Positives = 29/56 (51%)
Query: 521 SREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
++ + ER +ERR REK + + R R + E ++ R K ++ KR + K+
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Score = 32.0 bits (71), Expect = 1.7
Identities = 14/66 (21%), Positives = 30/66 (45%)
Query: 521 SREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSE 580
S+ +R ER+ +E + K R R+R ++ R+ + + +R ++ KE +
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 581 PAPEQE 586
+E
Sbjct: 86 RKERRE 91
Score = 30.4 bits (67), Expect = 4.8
Identities = 10/41 (24%), Positives = 28/41 (68%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERE 486
+ K+ + RRE+ ++R+++R ++++R +DR+ +R + +
Sbjct: 178 ERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
>gi|7662018 PHD finger protein 3 [Homo sapiens]
Length = 2039
Score = 70.5 bits (171), Expect = 4e-12
Identities = 63/222 (28%), Positives = 100/222 (45%), Gaps = 35/222 (15%)
Query: 357 PPFFPP----GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES-- 410
PP FPP G PP HLPPP LPPP P++P P PG P + P ++
Sbjct: 1820 PPNFPPQSMFGFPP-HLPPP-LLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASR 1877
Query: 411 --GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT--------SK 449
G + Y + R + P+G + P G D+ K
Sbjct: 1878 YIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK 1937
Query: 450 QWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+W+ + R + RDR +D+DR+R + +D+ER R +R D + N D++
Sbjct: 1938 EWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD 1997
Query: 506 RYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 545
+ + E E+ ER ++ + E+ R+R H++++ T R KS R
Sbjct: 1998 KPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 68.2 bits (165), Expect = 2e-11
Identities = 54/170 (31%), Positives = 81/170 (47%), Gaps = 19/170 (11%)
Query: 369 LPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGN 428
+P P LPPPP S+ PP P P PP PPP + T++ GH + PYG
Sbjct: 1602 IPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPP-VQQTVDYGHGRDISTNKVEQIPYGE 1660
Query: 429 VAFPHLPGSAPSWPSL-VDTSKQWDYYARREKDRDRERDRDRERD-----RDRDRERERT 482
P P + + + Q D Y +++RDRE DR+ + RD R+RE
Sbjct: 1661 -RITLRPDPLPERSTFETEHAGQRDRY---DRERDREPYFDRQSNVIADHRDFKRDRETH 1716
Query: 483 RERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERR 532
R+R+R+R V + D +R+ RE R +R ++ R+K++ RR
Sbjct: 1717 RDRDRDR------GVIDYDRDRFD-RERRPRD-DRAQSYRDKKDHSSSRR 1758
Score = 57.8 bits (138), Expect = 3e-08
Identities = 32/72 (44%), Positives = 37/72 (51%), Gaps = 13/72 (18%)
Query: 352 NFSKPPPFFPPGAPPTHLP--PPPFLPP---PPTVSTA-PPLIPPPGFPP-------PPG 398
N S PPPF P P LP PPP LPP PP + A P +PPPG PP P
Sbjct: 513 NMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTS 572
Query: 399 APPPSLIPTIES 410
PPP + P++ S
Sbjct: 573 VPPPGMPPSLSS 584
Score = 57.8 bits (138), Expect = 3e-08
Identities = 28/63 (44%), Positives = 32/63 (50%), Gaps = 14/63 (22%)
Query: 356 PPPFFPPGAPPTHLPP-------PPFLPPPPTVSTAPPLIPPPGFP-------PPPGAPP 401
PPP PP PP +PP PP +PPP + P +PPPG P PPP PP
Sbjct: 534 PPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPP 593
Query: 402 PSL 404
PSL
Sbjct: 594 PSL 596
Score = 55.8 bits (133), Expect = 1e-07
Identities = 44/114 (38%), Positives = 48/114 (42%), Gaps = 32/114 (28%)
Query: 354 SKPPPFFPPG----APPTHLPPP--------PFLPPPPTVSTAPPLI----------PPP 391
S PPP PP PP LPPP P LPPP STAPP + PPP
Sbjct: 572 SVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPP 631
Query: 392 GFPPP--PGAPPPSL----IPTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAP 439
G PPP P PP L +P S SS + A V+F GSAP
Sbjct: 632 GIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSF----GSAP 681
Score = 53.1 bits (126), Expect = 7e-07
Identities = 76/273 (27%), Positives = 103/273 (37%), Gaps = 92/273 (33%)
Query: 352 NFSKPPPFFPPGAPPTHLPPPPFLPPPPTVS-------------TAPPL-IPPPGFPPPP 397
N S P +PP P ++ PPPP PP ++ T PP+ IPPP PPP
Sbjct: 1498 NTSSRPGMYPP--PGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPL 1555
Query: 398 GAPPPSLIPTI---------------------ESGHSSGYDSRSARAFPYGNVAFP---- 432
PPP + P E G +S + S +A A P V P
Sbjct: 1556 PPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETA-AIPSAPVLPPPPVH 1614
Query: 433 ---HLPGSAP------SWPSLVDTSKQWDY-------------YARR------------- 457
PG P S P V + + + Y R
Sbjct: 1615 SSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQIPYGERITLRPDPLPERST 1674
Query: 458 -EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERG-- 514
E + +RDR DR+RDRE R+ DH F D E +R R+ +RG
Sbjct: 1675 FETEHAGQRDR---YDRERDREPYFDRQSNVIADHRD----FKRDRETHRDRD-RDRGVI 1726
Query: 515 -YERHRASREKEER-HRERRHREKEETRHKSSR 545
Y+R R RE+ R R + +R+K++ H SSR
Sbjct: 1727 DYDRDRFDRERRPRDDRAQSYRDKKD--HSSSR 1757
Score = 48.9 bits (115), Expect = 1e-05
Identities = 36/102 (35%), Positives = 46/102 (45%), Gaps = 19/102 (18%)
Query: 361 PPGAPPTHLPPPPFLPP-------PPTVSTAPPLIPPPGFPP--------PPGAPPPSLI 405
PPG P L PP PP PP+ S PP PPP + P PP P PS
Sbjct: 135 PPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQS 194
Query: 406 PTIES--GHSSGYDSRSARAFPYGNVAFPHLPGS--APSWPS 443
P +S + Y S S+ + Y + + +LP S +PS PS
Sbjct: 195 PPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPS 236
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 21/129 (16%)
Query: 451 WDYYARREKDRDRERDRDRERDRDRDRE----------RERTRERERERDHSPTPSVFNS 500
WD + E+D+D + D +RE +RD DR+ +R+ + E +RD+ +
Sbjct: 1265 WDDW---ERDQDMDEDYNREMERDMDRDVDRISRPMDMYDRSLDNEWDRDYG---RPLDE 1318
Query: 501 DEERYRYREYAERG-----YERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESE 555
E ++R R+ R +++R RE R+RE R R R R E
Sbjct: 1319 QESQFRERDIPSLPPLPPLPPLPPLDRYRDDRWREERNREHGYDRDFRDRGELRIREYPE 1378
Query: 556 EGDSHRRHK 564
GD+ R +
Sbjct: 1379 RGDTWREKR 1387
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/41 (51%), Positives = 24/41 (58%), Gaps = 12/41 (29%)
Query: 366 PTHLPPPPFLPPPPTVSTAPPLIPPPGF----PPPPGAPPP 402
P HLPPPP LPPPP ++P G+ PPPP PPP
Sbjct: 78 PHHLPPPP-LPPPP-------VMPGGGYGDWQPPPPPMPPP 110
Score = 38.1 bits (87), Expect = 0.023
Identities = 28/93 (30%), Positives = 32/93 (34%), Gaps = 38/93 (40%)
Query: 356 PPPFFPPGAPPTHLPPPPFLPPPPTVSTA-------------------PPLIP-----PP 391
PPP P G PPPP +PPPP + + P L+P PP
Sbjct: 88 PPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPP 147
Query: 392 GFPP--------------PPGAPPPSLIPTIES 410
PP PP PPPS P S
Sbjct: 148 ESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSS 180
Score = 37.4 bits (85), Expect = 0.039
Identities = 18/38 (47%), Positives = 19/38 (50%), Gaps = 3/38 (7%)
Query: 361 PPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPG 398
P PP LPPPP +P P PPP PPPPG
Sbjct: 78 PHHLPPPPLPPPPVMPGGGYGDWQP---PPPPMPPPPG 112
Score = 33.5 bits (75), Expect = 0.57
Identities = 18/48 (37%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 367 THLPPPPFLPPPPTVSTAPPLIPPPGF--PPPPGAPPPSLIPTIESGH 412
+H PPPP PPPP P P PG+ P AP S + H
Sbjct: 12 SHYPPPPVPPPPPV--ALPEASPGPGYSSSTTPAAPSSSGFMSFREQH 57
Score = 32.0 bits (71), Expect = 1.7
Identities = 20/51 (39%), Positives = 25/51 (49%), Gaps = 6/51 (11%)
Query: 368 HLPPPPFLPPPPTVSTAPPLIPPPGF---PPPPGAPPPSLI-PTIESGHSS 414
HLPP S+ P + PPPG PPP G PP S++ P+ SS
Sbjct: 1488 HLPPQE--SRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSS 1536
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 38/103 (36%)
Query: 356 PPPFFPPGAPPTHLPP--------PP---FLPPPPTVST--------------------A 384
PP ++PP + +LPP PP +L P P+ S+ A
Sbjct: 171 PPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQA 230
Query: 385 PPLIPPPGF-------PPPPGAPPPSLIPTIESGHSSGYDSRS 420
P P G PPPP APP + + SG ++S
Sbjct: 231 SPSRPSQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKS 273
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 66.6 bits (161), Expect = 6e-11
Identities = 43/150 (28%), Positives = 66/150 (44%), Gaps = 6/150 (4%)
Query: 446 DTSKQWDYYARREKDRDRE----RDRDRERDRDRDRERERTRERERERDHSPTPSVFNSD 501
D S+ Y R++ R R RD R R ++ R+R R+R +ERDHS S + +
Sbjct: 436 DCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSP-SKE 494
Query: 502 EERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRR-RHESEEGDSH 560
+ R R ++ R S KE HR R KE R +S N R R +S
Sbjct: 495 RDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEE 554
Query: 561 RRHKHKKSKRSKEGKEAGSEPAPEQESTEA 590
R H+ +S + + P+ E+E ++
Sbjct: 555 REHRQSRSPSKERDRRRWRSPSKERERRQS 584
Score = 59.3 bits (142), Expect = 1e-08
Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 14/172 (8%)
Query: 435 PGSAPSWPSLVDTSKQWDYYARREKDRDRE--------RDRDRERDRDRDRERERTRERE 486
P L SK+ D+ R ++R+ ++RD R R +ER+R + R
Sbjct: 479 PSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
Query: 487 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRS 546
++ + S S+E +R + +R R +ER R + EE H SRS
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRS 598
Query: 547 NSRRRHESEEGDSHRRHKHKKSKR-SKEGKEAGS-----EPAPEQESTEATP 592
+++ S S + H +S+ SKEG + S E P Q + +P
Sbjct: 599 PNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSP 650
Score = 58.9 bits (141), Expect = 1e-08
Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 6/140 (4%)
Query: 459 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTP------SVFNSDEERYRYREYAE 512
K RDR R R ++RD + ++ER+ R SP+ S +S E +R
Sbjct: 469 KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPS 528
Query: 513 RGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSK 572
+ +R ++ +ER R + EE H+ SRS S+ R + + ++S+ S
Sbjct: 529 KERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS 588
Query: 573 EGKEAGSEPAPEQESTEATP 592
E ++ +P ++S + P
Sbjct: 589 EERDHSRSRSPNKQSGYSRP 608
Score = 58.5 bits (140), Expect = 2e-08
Identities = 42/150 (28%), Positives = 65/150 (43%), Gaps = 6/150 (4%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRD----RERERTRERERERDHSPTPSVFNSD 501
D S+ Y R++ R R ++ R+ R R R+R R+R + RDHS + S N
Sbjct: 412 DRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSP-NKA 470
Query: 502 EERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHR 561
+R R R ++ S KE HR R KE +S S+ R H S
Sbjct: 471 RDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKE 530
Query: 562 RHKHKKSKRSKEGKEAGS-EPAPEQESTEA 590
R + + +KE + S P+ E+E ++
Sbjct: 531 RQRRQSRSPNKERDRSQSRSPSEEREHRQS 560
Score = 54.3 bits (129), Expect = 3e-07
Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 15/160 (9%)
Query: 448 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRY 507
+KQ D+ R + ++ RDR R R + R+R R+R + RD S + S + + +
Sbjct: 396 NKQRDH--SRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
Query: 508 REYAERGYERHRASREKEERHR------ERRHRE----KEETRHKSSRSNSRRRHESEEG 557
R + R R+ + +R R ER H + +E H+ SRS S+ R +
Sbjct: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
Query: 558 DSHRRHKHKKSKRSKEGKEAGSEPAPEQE---STEATPAE 594
S + H++S+ + ++ +P +E S +P+E
Sbjct: 514 SSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE 553
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/137 (21%), Positives = 57/137 (41%), Gaps = 14/137 (10%)
Query: 456 RREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGY 515
R+ + ++ERDR + R +RE ++R +ERD R R+R +
Sbjct: 534 RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD-------------RRRWRS-PSKER 579
Query: 516 ERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGK 575
ER ++ EER R +++ + R++S+ + S + H +S+ S +
Sbjct: 580 ERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES 639
Query: 576 EAGSEPAPEQESTEATP 592
+ P + +P
Sbjct: 640 DPSQSTVPRSPDWKRSP 656
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/169 (20%), Positives = 66/169 (39%), Gaps = 18/169 (10%)
Query: 436 GSAPSWPSLVDTSKQWDYYARREKDRD--------RERDRDRERDRDRDRERERTRERER 487
G + +W + + K+RD +E R + ++ R+ R+R +
Sbjct: 350 GRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK 409
Query: 488 ERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRER---------RHREKEE 538
RD S + S + + + R R R+ + +R R R R R +
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNK 469
Query: 539 TRHKS-SRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQE 586
R +S SRS S+ R S+ G + H++S+ + ++ + +E
Sbjct: 470 ARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKE 518
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/353 (22%), Positives = 134/353 (37%), Gaps = 33/353 (9%)
Query: 243 NSEKETALPSTKAEFTSPPS----LFKTGLPPSRNSTSSQSQTSTASRKANSSVGKWQDR 298
+S K T STK ++ PS + PSR ST ++ TS AS+ ++ + +
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTR--TSKASKASDVRCHQRRGT 117
Query: 299 YGRAESPDLRRLPGAIDVIGQTITISRVEGR-RRANENSNIQVLSERSATEVDNNFSKPP 357
+ R +P R + + T R+ R S ++ + + ++ +P
Sbjct: 118 HSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPR 177
Query: 358 PFFPP--GAPPTHLPPPPFLPPPPT-VSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSS 414
+ P +L + PP + + + L P P+ IP+ E +
Sbjct: 178 TSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAK---CQTPTGIPSKEKSDNP 234
Query: 415 GYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQWDYYARREKDRDRERDRDRERDRD 474
S S + YG + +P S+ +S+ Y + R + + R R
Sbjct: 235 S-PSSSRKVKSYGQMI---IPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRS 290
Query: 475 RDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHR 534
R ++RT R R N R R R+ RH SR H + + +
Sbjct: 291 RSGSQKRTHSRVRSHSWKR-----NHSRARSRTRKGILSQMGRHSQSRS----HSKGKSQ 341
Query: 535 EKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQES 587
+ T + RS++ R+ S+E R H H +S SKE GS +P +ES
Sbjct: 342 NQSRTPRRG-RSHNWSRNPSKE----RSHSHSRSS-SKERDHRGSS-SPRKES 387
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/112 (18%), Positives = 43/112 (38%)
Query: 481 RTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETR 540
R R R R + TPS ++D + + ++ + R + + R R + +
Sbjct: 77 RPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSP 136
Query: 541 HKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATP 592
++S R H + G + R ++ GK G +E +++ P
Sbjct: 137 SRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQP 188
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 457 REKDRDRERDR----------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 506
REK+R+RER+ +RE++R RDRER R R R R R S T SD R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT-----SDRRCSR 310
Query: 507 YREYAERGYERHRASREKEER------HRERRHREKEETRHKS-SRSNSRRRHESEEGDS 559
R++ R SR ++ R ER+HR + R +S SR +H S+ D
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDR 370
Query: 560 HRRHKHK-KSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ K K K KR + K++ + ++ +E T E
Sbjct: 371 EQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
Score = 63.9 bits (154), Expect = 4e-10
Identities = 47/132 (35%), Positives = 63/132 (47%), Gaps = 22/132 (16%)
Query: 459 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 518
+ R E DRD +++ ER +ERERER+ + ER R RE ER ER
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----------ERERKRRREEEEREKERA 284
Query: 519 RASREKEERHRER-RHREKEETR-------HKSSRSNSRRRHESEE---GDSHRRHKHKK 567
R RE+ +R R R RH + R HK SRS RRR S + SH R + K
Sbjct: 285 R-DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 568 SKRSKEGKEAGS 579
RS++ + + S
Sbjct: 344 RSRSRDRRRSKS 355
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 15/130 (11%)
Query: 452 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYA 511
D ++EK ER+++RER+R+ ERER R RE E ++ER R RE
Sbjct: 244 DERLKKEKQEREEREKERERERE---ERERKRRREEEE----------REKERARDRERR 290
Query: 512 ERGYERHRASREKEERH--RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
+R R R S +R R R H+ + SRS RRR S + + + +
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
Query: 570 RSKEGKEAGS 579
R + ++ S
Sbjct: 351 RRSKSRDRKS 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 1/134 (0%)
Query: 448 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS-DEERYR 506
S+ ++ R DR R RD +R R R+R R R+R+R R R H + S +R R
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 507 YREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 566
+ + Y+ SR++E+ + + ++ KSS + R +SE+ ++ +
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 567 KSKRSKEGKEAGSE 580
K++ + ++ SE
Sbjct: 413 KNEVNGTSEDIKSE 426
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 27/132 (20%)
Query: 458 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 517
E+ +++ R R E DRD ++E+ ERE+ ER R RE ER R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREK-------------EREREREERERKRRR 274
Query: 518 HRASREKEE-RHRERRHREKEETRHKS-------------SRSNSRRRHESEEGDSHRRH 563
REKE R RERR R + +RH S RS SR R S D R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 564 KHKKSKRSKEGK 575
H +S+R +
Sbjct: 335 SHDRSERKHRSR 346
Score = 56.2 bits (134), Expect = 8e-08
Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 26/151 (17%)
Query: 456 RREKDRDRERDRDRER---------------DRDRDRERERTRERERERDHSPTPSVFNS 500
R E++R++ER RDRER DR R R+ R R RER S +
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR-----SR 328
Query: 501 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEE-GD 558
D R R + +ER +HR SR ++ R + R R+ + R KS R R+ E E+ G
Sbjct: 329 DRRRSRSHDRSER---KHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 559 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
++ K R K+ ++ +E E
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
Score = 30.4 bits (67), Expect = 4.8
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 446 DTSKQWDYYARREKDRDRERDRD--RERDRDRDRERER-TRERERERDHSPTPSVFNSDE 502
D S++ R++ R + RDR + R + RDRE++R ++E+E+ SV +
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 503 ER 504
E+
Sbjct: 397 EK 398
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 66.6 bits (161), Expect = 6e-11
Identities = 50/156 (32%), Positives = 73/156 (46%), Gaps = 24/156 (15%)
Query: 457 REKDRDRERDR----------DRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 506
REK+R+RER+ +RE++R RDRER R R R R R S T SD R
Sbjct: 257 REKEREREREERERKRRREEEEREKERARDRER-RKRSRSRSRHSSRT-----SDRRCSR 310
Query: 507 YREYAERGYERHRASREKEER------HRERRHREKEETRHKS-SRSNSRRRHESEEGDS 559
R++ R SR ++ R ER+HR + R +S SR +H S+ D
Sbjct: 311 SRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDR 370
Query: 560 HRRHKHK-KSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ K K K KR + K++ + ++ +E T E
Sbjct: 371 EQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTE 406
Score = 63.9 bits (154), Expect = 4e-10
Identities = 47/132 (35%), Positives = 63/132 (47%), Gaps = 22/132 (16%)
Query: 459 KDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 518
+ R E DRD +++ ER +ERERER+ + ER R RE ER ER
Sbjct: 235 RKRTEEPDRDERLKKEKQEREEREKERERERE----------ERERKRRREEEEREKERA 284
Query: 519 RASREKEERHRER-RHREKEETR-------HKSSRSNSRRRHESEE---GDSHRRHKHKK 567
R RE+ +R R R RH + R HK SRS RRR S + SH R + K
Sbjct: 285 R-DRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKH 343
Query: 568 SKRSKEGKEAGS 579
RS++ + + S
Sbjct: 344 RSRSRDRRRSKS 355
Score = 61.6 bits (148), Expect = 2e-09
Identities = 39/130 (30%), Positives = 59/130 (45%), Gaps = 15/130 (11%)
Query: 452 DYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYA 511
D ++EK ER+++RER+R+ ERER R RE E ++ER R RE
Sbjct: 244 DERLKKEKQEREEREKERERERE---ERERKRRREEEE----------REKERARDRERR 290
Query: 512 ERGYERHRASREKEERH--RERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSK 569
+R R R S +R R R H+ + SRS RRR S + + + +
Sbjct: 291 KRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDR 350
Query: 570 RSKEGKEAGS 579
R + ++ S
Sbjct: 351 RRSKSRDRKS 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/134 (25%), Positives = 64/134 (47%), Gaps = 1/134 (0%)
Query: 448 SKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNS-DEERYR 506
S+ ++ R DR R RD +R R R+R R R+R+R R R H + S +R R
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRR 352
Query: 507 YREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHK 566
+ + Y+ SR++E+ + + ++ KSS + R +SE+ ++ +
Sbjct: 353 SKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNTESKESDT 412
Query: 567 KSKRSKEGKEAGSE 580
K++ + ++ SE
Sbjct: 413 KNEVNGTSEDIKSE 426
Score = 60.5 bits (145), Expect = 4e-09
Identities = 43/132 (32%), Positives = 56/132 (42%), Gaps = 27/132 (20%)
Query: 458 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 517
E+ +++ R R E DRD ++E+ ERE+ ER R RE ER R
Sbjct: 228 EELKEKLRKRTEEPDRDERLKKEKQEREEREK-------------EREREREERERKRRR 274
Query: 518 HRASREKEE-RHRERRHREKEETRHKS-------------SRSNSRRRHESEEGDSHRRH 563
REKE R RERR R + +RH S RS SR R S D R
Sbjct: 275 EEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 564 KHKKSKRSKEGK 575
H +S+R +
Sbjct: 335 SHDRSERKHRSR 346
Score = 56.2 bits (134), Expect = 8e-08
Identities = 45/151 (29%), Positives = 67/151 (44%), Gaps = 26/151 (17%)
Query: 456 RREKDRDRERDRDRER---------------DRDRDRERERTRERERERDHSPTPSVFNS 500
R E++R++ER RDRER DR R R+ R R RER S +
Sbjct: 274 REEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSR-----SR 328
Query: 501 DEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKS-SRSNSRRRHESEE-GD 558
D R R + +ER +HR SR ++ R + R R+ + R KS R R+ E E+ G
Sbjct: 329 DRRRSRSHDRSER---KHR-SRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGS 384
Query: 559 SHRRHKHKKSKRSKEGKEAGSEPAPEQESTE 589
++ K R K+ ++ +E E
Sbjct: 385 DDKKSSVKSGSREKQSEDTNTESKESDTKNE 415
Score = 30.4 bits (67), Expect = 4.8
Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Query: 446 DTSKQWDYYARREKDRDRERDRD--RERDRDRDRERER-TRERERERDHSPTPSVFNSDE 502
D S++ R++ R + RDR + R + RDRE++R ++E+E+ SV +
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSR 396
Query: 503 ER 504
E+
Sbjct: 397 EK 398
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 66.2 bits (160), Expect = 8e-11
Identities = 43/133 (32%), Positives = 68/133 (51%), Gaps = 11/133 (8%)
Query: 457 REKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYE 516
R DR+R+RDRDR+ +DR+R R+R+R R S + S S E R++E ER E
Sbjct: 24 RTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKE-RERDKE 82
Query: 517 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
R R K++R R++ +++ R +SS S R G + K + SK+ +E +
Sbjct: 83 R---DRNKKDRDRDKDGHRRDKDRKRSSLSPGR-------GKDFKSRKDRDSKKDEEDEH 132
Query: 577 AGSEPAPEQESTE 589
+P + S E
Sbjct: 133 GDKKPKAQPLSLE 145
Score = 64.3 bits (155), Expect = 3e-10
Identities = 45/143 (31%), Positives = 66/143 (46%), Gaps = 21/143 (14%)
Query: 458 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYER 517
+KDRD ++ +R R R RER+R+RD +PS D +R+R R+ RG R
Sbjct: 8 KKDRDASPSKE-----ERKRSRTPDRERDRDRDRKSSPS---KDRKRHRSRD-RRRGGSR 58
Query: 518 HRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKK--------SK 569
R+ + RERRH+E+E + + R R + D HRR K +K K
Sbjct: 59 SRSRSRSKSAERERRHKERERDKERDRNKKDRDR----DKDGHRRDKDRKRSSLSPGRGK 114
Query: 570 RSKEGKEAGSEPAPEQESTEATP 592
K K+ S+ E E + P
Sbjct: 115 DFKSRKDRDSKKDEEDEHGDKKP 137
Score = 52.4 bits (124), Expect = 1e-06
Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 13/144 (9%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDR--DRDRERERTRERERERDHSPTPSVFNSDEE 503
D + D + +DR+R R R+R R R R R R++ ERER H D+E
Sbjct: 27 DRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKER----ERDKE 82
Query: 504 RYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRH 563
R R ++ +R + HR R ++R+ R K +S R + +E D H
Sbjct: 83 RDRNKKDRDRDKDGHR-------RDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDK 135
Query: 564 KHKKSKRSKEGKEAGSEPAPEQES 587
K K S E A + E E+
Sbjct: 136 KPKAQPLSLEELLAKKKAEEEAEA 159
Score = 43.1 bits (100), Expect = 7e-04
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 35/155 (22%)
Query: 457 REKDRDRERDR---DRERDRD---RDRERERT-------------RERERERDHSPT--- 494
+E++RD+ERDR DR+RD+D RD++R+R+ ++R+ ++D
Sbjct: 75 KERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGD 134
Query: 495 --PSVFNSDEERYRYREYAERGYERHRASREKEERHRE---RRHREKEETRHKSSRSNSR 549
P E ++ AE E K ER E RR +E EE + +
Sbjct: 135 KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEEERKK 194
Query: 550 RRHESEEG--------DSHRRHKHKKSKRSKEGKE 576
R+ + G + RR + ++ +R G E
Sbjct: 195 RKQFQDLGRKMLEDPQERERRERRERMERETNGNE 229
Score = 32.3 bits (72), Expect = 1.3
Identities = 28/101 (27%), Positives = 45/101 (44%), Gaps = 16/101 (15%)
Query: 476 DRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHRE 535
+RE E + R++E + +EER + +++ + G + +E+E R ERR R
Sbjct: 168 EREAEALKRRQQEVEERQRML----EEERKKRKQFQDLGRKMLEDPQERERR--ERRERM 221
Query: 536 KEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
+ ET +E EEG R + KSK KE
Sbjct: 222 ERET----------NGNEDEEGRQKIREEKDKSKELHAIKE 252
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo
sapiens]
Length = 1758
Score = 65.9 bits (159), Expect = 1e-10
Identities = 68/251 (27%), Positives = 93/251 (37%), Gaps = 37/251 (14%)
Query: 342 SERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPP--PPGA 399
SERS + P F P +PPPP PPPP PP +PPP F P PPG
Sbjct: 539 SERSQRTQGPSLPATPVFVP-------VPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQ 591
Query: 400 PPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLPG--SAPSWPSLVDTSKQWDYYARR 457
PPP +GY P G FP P S P S V T+ +
Sbjct: 592 PPP-----------AGYS-----VPPPG---FPPAPANLSTPWVSSGVQTAHSNTIPTTQ 632
Query: 458 EKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFN-SDEERYRYREYAERGYE 516
RE E R++ R +E ++ +S + ++ S R R Y+ R +
Sbjct: 633 APPLSRE-----EFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYS-RSFS 686
Query: 517 RHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKE 576
R + RR R K SRS+ R S R H +S ++ G+
Sbjct: 687 RSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQS 746
Query: 577 AGSEPAPEQES 587
P+ E+
Sbjct: 747 PNKRNVPQGET 757
Score = 39.3 bits (90), Expect = 0.010
Identities = 25/105 (23%), Positives = 53/105 (50%), Gaps = 5/105 (4%)
Query: 487 RERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE-TRHKSSR 545
R + HS +PSV S + R + +S E ++ ++++ +EK++ +HK +
Sbjct: 1655 RNQSHS-SPSV--SPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHK 1711
Query: 546 SNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEA 590
+ + E + ++HKHKK K+SK+ K+ E + + ++
Sbjct: 1712 KHKKHAGTEVELEKSQKHKHKK-KKSKKNKDKEKEKEKDDQKVKS 1755
Score = 34.3 bits (77), Expect = 0.33
Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 28/161 (17%)
Query: 453 YYARREKDRDR-ERDRDRERDRDRDRERER----------TRERERERDHSPTP----SV 497
YY R RD E++R RE +R E+ R + SP ++
Sbjct: 777 YYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNI 836
Query: 498 FNSDEERYRYREYAERGYERHRA----SREKEERHRERRHREKEETRHKSSRSNSRRRHE 553
NS R R +Y G + HR+ S E+ H +K+ T+ K S E
Sbjct: 837 RNSPFTRGRREDYV--GGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKES------E 888
Query: 554 SEEGDSHRRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ GD + +KHKK ++ ++G+E+ PE T E
Sbjct: 889 NAPGDG-KGNKHKKHRKRRKGEESEGFLNPELLETSRKSRE 928
Score = 33.5 bits (75), Expect = 0.57
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 21/95 (22%)
Query: 479 RERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEE 538
R + + R HS + S S + S++K+++ +++H K+
Sbjct: 1668 RSHSPSGSQTRSHSSSASSAESQD------------------SKKKKKKKEKKKH--KKH 1707
Query: 539 TRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKE 573
+HK + ++ E E+ H +HK KKSK++K+
Sbjct: 1708 KKHKKHKKHAGTEVELEKSQKH-KHKKKKSKKNKD 1741
Score = 30.8 bits (68), Expect = 3.7
Identities = 29/154 (18%), Positives = 64/154 (41%), Gaps = 7/154 (4%)
Query: 447 TSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERYR 506
T ++ D A +K+ + + + D +RER E ++ TP N+
Sbjct: 985 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKSSSSS 1044
Query: 507 YREYAERGYERHRASREKEERHRERRHREKEETRH------KSSRSNSRRRHESEEGDSH 560
++ G R S+ +E H+E + ++E+ + KS + ++ + + +
Sbjct: 1045 QKDEKITGTPRKAHSKSAKE-HQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKN 1103
Query: 561 RRHKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 594
+ +K KR ++ +E G + E S + + E
Sbjct: 1104 KPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLE 1137
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.9 bits (159), Expect = 1e-10
Identities = 60/267 (22%), Positives = 110/267 (41%), Gaps = 29/267 (10%)
Query: 332 ANENSNIQVLSERSATEVDNNFSKPPPFFPPGAPPTHLPPPPFL----PPPPTVSTAPPL 387
+N S+ Q+ ++ S +V + K P F +HLPPPP L PPP P
Sbjct: 371 SNTKSSSQIPAQPSVAKVP--YGKGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGR 428
Query: 388 IPPPGFPPPPGAPPPSLIPTIESGHSSGYDS-----RSARAFPYGNVAFPHLPGSAPSWP 442
P FP I S + R R + A
Sbjct: 429 --PGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLK 486
Query: 443 SLVDTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDE 502
L + + E+ R+RER+++RER+++ ++E+E+ RE+ERE+ D
Sbjct: 487 RLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREK-----------DR 535
Query: 503 ERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRR 562
ER + E+ E + ++ E +ER+ +++E + + ++ + +E +
Sbjct: 536 ERQQ-----EKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELE 590
Query: 563 HKHKKSKRSKEGKEAGSEPAPEQESTE 589
+ +K + E +E EP E++ +E
Sbjct: 591 KEREKLEEKIEPREPNLEPMVEKQESE 617
Score = 55.1 bits (131), Expect = 2e-07
Identities = 35/141 (24%), Positives = 67/141 (47%), Gaps = 4/141 (2%)
Query: 446 DTSKQWDYYARREKDRDRERDRDRERDRDRDRERERTRERERERDHSPTPSVFNSDEERY 505
+ K+ + +E+++DRER +++E++ ++++E++R E+ER+++ E+
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKEL 577
Query: 506 RYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHES---EEGDSHRR 562
+ + E+ E + REK E E R E K NS + E DS+R
Sbjct: 578 QKMKEQEKECELEK-EREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRS 636
Query: 563 HKHKKSKRSKEGKEAGSEPAP 583
K + E+GS+P P
Sbjct: 637 EKEATPVVHETEPESGSQPRP 657
Score = 39.7 bits (91), Expect = 0.008
Identities = 61/248 (24%), Positives = 84/248 (33%), Gaps = 45/248 (18%)
Query: 375 LPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHL 434
LPPPP P I P PPP P P+ E+ + S+ P
Sbjct: 1058 LPPPPPPPQPPAPIQPQSVPPPI-QPEAEKFPSTETATLAQKPSQDTEK--------PLE 1108
Query: 435 PGSAPSWPSLVDTSKQWDYYA---RREKDRDRERDRDRERDRDRDRERERTRERE----- 486
P S V T Q A + EK ++ +D +R R R ++
Sbjct: 1109 PVSTVQVEPAVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPPR 1168
Query: 487 ------RERDHSPTPSVFNSDEERYRYREYAERG---------------YERHRASREKE 525
RERD P Y R + RG Y ++R ++ +
Sbjct: 1169 TYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRDNKPRA 1228
Query: 526 ER--HRERRHREKEETRHKSSRSN---SRRRHESEEGDSHRR-HKHKKSKRS-KEGKEAG 578
E R RE+ ETR +SS RRR E D+ H+ K S +GK
Sbjct: 1229 EHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESASDKDSLSKGKLPK 1288
Query: 579 SEPAPEQE 586
E PE +
Sbjct: 1289 REERPENK 1296
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,033,444
Number of Sequences: 37866
Number of extensions: 2064212
Number of successful extensions: 57792
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1020
Number of HSP's successfully gapped in prelim test: 1239
Number of HSP's that attempted gapping in prelim test: 17309
Number of HSP's gapped (non-prelim): 18708
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.