BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|39930571 leucine rich repeat containing 56 [Homo sapiens] (542 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|39930571 leucine rich repeat containing 56 [Homo sapiens] 1114 0.0 gi|218931217 leucine rich repeat containing 61 [Homo sapiens] 58 2e-08 gi|13027616 leucine rich repeat containing 61 [Homo sapiens] 58 2e-08 gi|117414162 sodium channel associated protein 2 isoform a [Homo... 52 1e-06 gi|4826651 hypothetical protein LOC755 [Homo sapiens] 52 2e-06 gi|164607156 axonemal dynein light chain 1 [Homo sapiens] 51 2e-06 gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 50 7e-06 gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 50 7e-06 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 47 6e-05 gi|21389483 leucine-rich repeats and guanylate kinase domain con... 46 1e-04 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 46 1e-04 gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 45 1e-04 gi|190684671 mitogen-activated protein kinase binding protein 1 ... 45 1e-04 gi|190684677 mitogen-activated protein kinase binding protein 1 ... 45 1e-04 gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap... 45 2e-04 gi|40556370 PHD finger protein 15 [Homo sapiens] 44 3e-04 gi|116268109 nucleotide-binding oligomerization domains 27 [Homo... 44 3e-04 gi|223718151 leucine rich transmembrane and 0-methyltransferase ... 44 4e-04 gi|21687175 leucine rich transmembrane and 0-methyltransferase d... 44 4e-04 gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 44 4e-04 gi|24308207 leucine rich repeat containing 47 [Homo sapiens] 44 4e-04 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 44 4e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 5e-04 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 44 5e-04 gi|238859651 pleckstrin homology domain containing family A memb... 43 8e-04 gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo... 43 8e-04 gi|117414154 sodium channel associated protein 2 isoform b [Homo... 43 8e-04 gi|171543895 ataxin 2 [Homo sapiens] 42 0.001 gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 42 0.001 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 42 0.001 >gi|39930571 leucine rich repeat containing 56 [Homo sapiens] Length = 542 Score = 1114 bits (2882), Expect = 0.0 Identities = 542/542 (100%), Positives = 542/542 (100%) Query: 1 MDLGWDRSRGPRRSTSSVRVRELSWQGLHNPCPQSKGPGSQRDRLGEQLVEEYLSPARLQ 60 MDLGWDRSRGPRRSTSSVRVRELSWQGLHNPCPQSKGPGSQRDRLGEQLVEEYLSPARLQ Sbjct: 1 MDLGWDRSRGPRRSTSSVRVRELSWQGLHNPCPQSKGPGSQRDRLGEQLVEEYLSPARLQ 60 Query: 61 ALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQV 120 ALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQV Sbjct: 61 ALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQV 120 Query: 121 LWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQVRY 180 LWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQVRY Sbjct: 121 LWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQVRY 180 Query: 181 LQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPP 240 LQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPP Sbjct: 181 LQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPP 240 Query: 241 APPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVR 300 APPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVR Sbjct: 241 APPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVR 300 Query: 301 GGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPG 360 GGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPG Sbjct: 301 GGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPG 360 Query: 361 DPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEE 420 DPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEE Sbjct: 361 DPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEE 420 Query: 421 QVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLR 480 QVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLR Sbjct: 421 QVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLR 480 Query: 481 VLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSHPSPV 540 VLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSHPSPV Sbjct: 481 VLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSHPSPV 540 Query: 541 PT 542 PT Sbjct: 541 PT 542 >gi|218931217 leucine rich repeat containing 61 [Homo sapiens] Length = 259 Score = 58.2 bits (139), Expect = 2e-08 Identities = 49/133 (36%), Positives = 66/133 (49%), Gaps = 7/133 (5%) Query: 98 LKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLC 157 LKL G L L LG LG L+ L L+ L L +ASL L L S N ++ L PL Sbjct: 36 LKLRGLGLADLGCLGECLG-LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLA 94 Query: 158 LLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRA 217 E L+ L+ GN + GQ++ L P L L L L L +N + +Y A Sbjct: 95 TCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARL------SNPLCANPSYWA 148 Query: 218 EVRKLIPQLQVLD 230 VR+L+P L+V+D Sbjct: 149 AVRELLPGLKVID 161 >gi|13027616 leucine rich repeat containing 61 [Homo sapiens] Length = 259 Score = 58.2 bits (139), Expect = 2e-08 Identities = 49/133 (36%), Positives = 66/133 (49%), Gaps = 7/133 (5%) Query: 98 LKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLC 157 LKL G L L LG LG L+ L L+ L L +ASL L L S N ++ L PL Sbjct: 36 LKLRGLGLADLGCLGECLG-LEWLDLSGNALTHLGPLASLRQLAVLNVSNNRLTGLEPLA 94 Query: 158 LLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRA 217 E L+ L+ GN + GQ++ L P L L L L L +N + +Y A Sbjct: 95 TCENLQSLNAAGNLLATPGQLQCLAGLPCLEYLRLRDPLARL------SNPLCANPSYWA 148 Query: 218 EVRKLIPQLQVLD 230 VR+L+P L+V+D Sbjct: 149 AVRELLPGLKVID 161 >gi|117414162 sodium channel associated protein 2 isoform a [Homo sapiens] Length = 1032 Score = 52.4 bits (124), Expect = 1e-06 Identities = 47/144 (32%), Positives = 71/144 (49%), Gaps = 12/144 (8%) Query: 91 HLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNI 150 H+ NL L L+ + + + L T L L L L+ + ++G+ L L L SYN+I Sbjct: 63 HIWNLQHLDLSSNQISRIEGLNT-LTKLCTLNLSCNLITKVEGLEELINLTRLNVSYNHI 121 Query: 151 SDLSPLCLLE----QLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPT 206 DLS L L +L +DL N ++ + + LQ L LT NL+ + G Sbjct: 122 DDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHL--LQCMVGLHFLT---NLILEKD--GDD 174 Query: 207 NKVPRGYNYRAEVRKLIPQLQVLD 230 N V R YRA + + +PQL++LD Sbjct: 175 NPVCRLPGYRAVILQTLPQLRILD 198 >gi|4826651 hypothetical protein LOC755 [Homo sapiens] Length = 256 Score = 51.6 bits (122), Expect = 2e-06 Identities = 40/140 (28%), Positives = 62/140 (44%), Gaps = 10/140 (7%) Query: 128 LADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRL 187 L D+ +P+L+ + S N+IS L P+ ++L L L N + L ++ YL+ PRL Sbjct: 30 LTDISICQEMPSLEVITLSVNSISTLEPVSRCQRLSELYLRRNRIPSLAELFYLKGLPRL 89 Query: 188 AMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPPAPPRLSQ 247 +L L N C +P + YR V + +P+LQ LD + Sbjct: 90 RVLWLAEN-PCCGTSP---------HRYRMTVLRTLPRLQKLDNQAVTEEELSRALSEGE 139 Query: 248 DWLAVKEAIKKGNGLPPLDC 267 + A E G+G P L C Sbjct: 140 EITAAPEREGTGHGGPKLCC 159 >gi|164607156 axonemal dynein light chain 1 [Homo sapiens] Length = 190 Score = 51.2 bits (121), Expect = 2e-06 Identities = 40/143 (27%), Positives = 73/143 (51%), Gaps = 10/143 (6%) Query: 92 LPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASL-PALKELYASYNNI 150 L N ++L L+ + + + +L L +L++L L R + +L+G+ ++ L+EL+ SYN I Sbjct: 47 LANCEKLSLSTNCIEKIANLN-GLKNLRILSLGRNNIKNLNGLEAVGDTLEELWISYNFI 105 Query: 151 SDLSPLCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVP 210 L + ++++L++L + N V+D + L P L L GN + K Sbjct: 106 EKLKGIHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPL--------EEKHS 157 Query: 211 RGYNYRAEVRKLIPQLQVLDEVP 233 N+ E K +P+L+ LD P Sbjct: 158 AENNWIEEATKRVPKLKKLDGTP 180 >gi|206725447 leucine rich repeat containing 23 isoform a [Homo sapiens] Length = 343 Score = 49.7 bits (117), Expect = 7e-06 Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 15/141 (10%) Query: 92 LPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNIS 151 L +L ++L G+ L S LG +L L+ L+LA+ L ++G+ L L L+ N I Sbjct: 178 LISLHTVELRGNQLEST--LGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQID 235 Query: 152 DLSPLCL-LEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVP 210 LS ++ L+ L+L GN V +LG++ L+ P+L L L N P T Sbjct: 236 TLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDN-----PCTDET---- 286 Query: 211 RGYNYRAEVRKLIPQLQVLDE 231 +YR E +P L+ LD+ Sbjct: 287 ---SYRQEALVQMPYLERLDK 304 Score = 35.0 bits (79), Expect = 0.17 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 18/111 (16%) Query: 105 LGSLRDLGTSLGHLQV-LWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLE 163 L L G L H V L + L D+ + S L+ + S N+++DLSPL L L Sbjct: 57 LSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLL 116 Query: 164 VLDLEGNSVE--DLGQVRYLQLC---------------PRLAMLTLEGNLV 197 L +GN + + ++ YLQ+ PRL L L+GN + Sbjct: 117 WLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSI 167 >gi|42542396 leucine rich repeat containing 23 isoform a [Homo sapiens] Length = 343 Score = 49.7 bits (117), Expect = 7e-06 Identities = 45/141 (31%), Positives = 70/141 (49%), Gaps = 15/141 (10%) Query: 92 LPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNIS 151 L +L ++L G+ L S LG +L L+ L+LA+ L ++G+ L L L+ N I Sbjct: 178 LISLHTVELRGNQLEST--LGINLPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQID 235 Query: 152 DLSPLCL-LEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVP 210 LS ++ L+ L+L GN V +LG++ L+ P+L L L N P T Sbjct: 236 TLSGFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDN-----PCTDET---- 286 Query: 211 RGYNYRAEVRKLIPQLQVLDE 231 +YR E +P L+ LD+ Sbjct: 287 ---SYRQEALVQMPYLERLDK 304 Score = 35.0 bits (79), Expect = 0.17 Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 18/111 (16%) Query: 105 LGSLRDLGTSLGHLQV-LWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLE 163 L L G L H V L + L D+ + S L+ + S N+++DLSPL L L Sbjct: 57 LSLLCKTGNGLAHAYVKLEVKERDLTDIYLLRSYIHLRYVDISENHLTDLSPLNYLTHLL 116 Query: 164 VLDLEGNSVE--DLGQVRYLQLC---------------PRLAMLTLEGNLV 197 L +GN + + ++ YLQ+ PRL L L+GN + Sbjct: 117 WLKADGNRLRSAQMNELPYLQIASFAYNQITDTEGISHPRLETLNLKGNSI 167 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 46.6 bits (109), Expect = 6e-05 Identities = 58/210 (27%), Positives = 77/210 (36%), Gaps = 22/210 (10%) Query: 350 PPEQLPQHRPGDPAASTSTPEPDPADSSDFL-ALAGLRAWREHGVRPLPYRHPESQ--QE 406 PPE+ P P P AS +P P+ +S AL R E + P P P S + Sbjct: 452 PPEESPTSPP--PEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPES 509 Query: 407 GAVAPW--GPRRVPEEQVHQAEPKTPSSPPSLAS--------EPSGTSSQHLVPSPPKH- 455 +P P PEE +TP SPP AS P + L SPP Sbjct: 510 SPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA 569 Query: 456 ----PRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPR 511 P P +S S P + + R+ + L ASRLSP Sbjct: 570 SRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPP 629 Query: 512 AQGCPGPKPAPDAAARPPRAAELSHPSPVP 541 + P P ++ PP E+S SP+P Sbjct: 630 PEDSPMSPPPEESPMSPP--PEVSRLSPLP 657 Score = 42.7 bits (99), Expect = 8e-04 Identities = 79/296 (26%), Positives = 99/296 (33%), Gaps = 67/296 (22%) Query: 263 PPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVRGGPLPEGL-----LSED-LAPE 316 PP + P P PE S ASR P + PLPE L L E L+P Sbjct: 443 PPEESPLSPP-----PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP 497 Query: 317 DNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADS 376 S L+ +P L E PPE+ P P+ + TP P ++ Sbjct: 498 PEESPLSPPPES----SPFSPLEE-----SPLSPPEESP------PSPALETPLSPPPEA 542 Query: 377 SDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPK-TPSSPPS 435 S + E + P P P S A P PEE P+ +P SPP Sbjct: 543 SPLSP-----PFEESPLSPPPEELPTSPPPEASRLSPP---PEESPMSPPPEESPMSPPP 594 Query: 436 LASE--------PSGTSSQHLVPSPPKH-----PRPRDSGSSSPRWSTDLQSRGRRLRVL 482 AS P + SPP P P DS S P + + R Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR-- 652 Query: 483 GSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCP-GPKPAPDAAARPPRAAELSHP 537 L L V SRLSP + P P P + PP A+ LS P Sbjct: 653 ----------------LSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692 Score = 37.0 bits (84), Expect = 0.046 Identities = 52/201 (25%), Positives = 69/201 (34%), Gaps = 14/201 (6%) Query: 351 PEQLPQHRPGDPAASTS--TPEPDPADSSDFLALAGLRAWREHGVRPLPY-----RHPES 403 PE+LP G+P+ S P+P P S + A A G P+ PES Sbjct: 912 PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPES 971 Query: 404 QQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGS 463 + PE EP P P P G +S L+ P P S Sbjct: 972 PLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHS 1031 Query: 464 SSPRWSTDLQSR--GRRLRVLGSWGP-GLGDGVAAVPVLRALEVASRLSPRAQGCPGPKP 520 P+ S Q L V P G GV+ L +E P CP +P Sbjct: 1032 LVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE---CPALEP 1088 Query: 521 APDAAARPPRAAELSHPSPVP 541 + + P +LS P+P P Sbjct: 1089 SA-TSPLPSPMGDLSCPAPSP 1108 Score = 33.1 bits (74), Expect = 0.66 Identities = 69/254 (27%), Positives = 85/254 (33%), Gaps = 48/254 (18%) Query: 236 HTGPPAPPRL--------------SQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELS 281 HT PP PR S D LAV E+ G G P L Sbjct: 2227 HTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALE 2286 Query: 282 LPETQSRASRP--WPFSLLVRGGPLPEGLLS--EDLAPEDNTSSLTHGAGQVLCGNPTKG 337 + + + AS P P +L P L E P+ + LT A QV +P G Sbjct: 2287 VKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLG 2346 Query: 338 LRERRH---QCQAREPPEQLPQHRPG---DPAASTS-TPEPDPADSSDFLALAGLRAWRE 390 LR + Q A PP RPG DP A TP P P AL Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP------ 2400 Query: 391 HGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVP 450 R LP P S+ + P+ Q P TP + A PS + + P Sbjct: 2401 ---RSLP-SDPFSRVPAS---------PQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP 2447 Query: 451 S----PPKHPRPRD 460 PP P+ RD Sbjct: 2448 DPYSRPPSRPQSRD 2461 >gi|21389483 leucine-rich repeats and guanylate kinase domain containing [Homo sapiens] Length = 825 Score = 45.8 bits (107), Expect = 1e-04 Identities = 31/102 (30%), Positives = 54/102 (52%), Gaps = 2/102 (1%) Query: 94 NLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDL 153 NL L L + + ++ L +++L L+ + + G+ L AL+ L S+N IS L Sbjct: 238 NLIHLSLANNKITTINGLNKL--PIKILCLSNNQIEMITGLEDLKALQNLDLSHNQISSL 295 Query: 154 SPLCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGN 195 L + LEV++LE N + +L ++ Y++ P L +L L N Sbjct: 296 QGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLEN 337 Score = 37.0 bits (84), Expect = 0.046 Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 25/103 (24%) Query: 117 HLQVLWLARCGLADLDGIASLPALKELYASYNN----------------------ISDLS 154 HLQ L L+ + DL ++ +P L EL AS NN IS++ Sbjct: 150 HLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEIC 209 Query: 155 PLCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLV 197 L L L L+GN +E++ L++C L L+L N + Sbjct: 210 DLSAYHALTKLILDGNEIEEISG---LEMCNNLIHLSLANNKI 249 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 45.8 bits (107), Expect = 1e-04 Identities = 58/204 (28%), Positives = 78/204 (38%), Gaps = 21/204 (10%) Query: 350 PPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAV 409 PP P + P P T +P+ + + ++ P P PE +Q+ ++ Sbjct: 730 PPSPPPSYHPPPPP----TKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE-EQDLSM 784 Query: 410 APWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLV--------PSPPKHPRPRDS 461 A + P V EP PS P L S P+ +SS P PP P Sbjct: 785 ADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 Query: 462 GSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPG--PK 519 SS+P L + + GP D V A V +L RL R+ G PG P Sbjct: 845 ASSAPGHVAKLPQK-EPVGCSKGGGPPRED-VGAPLVTPSLLQMVRL--RSVGAPGGAPT 900 Query: 520 PA--PDAAARPPRAAELSHPSPVP 541 PA P A +P R A SPVP Sbjct: 901 PALGPSAPQKPLRRALSGRASPVP 924 Score = 42.7 bits (99), Expect = 8e-04 Identities = 70/293 (23%), Positives = 105/293 (35%), Gaps = 65/293 (22%) Query: 201 PAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPPAPPRLSQDWLAVKEAIKKGN 260 PAP P + P V KL PQ + P + PPR V ++ + Sbjct: 840 PAPAPASSAP------GHVAKL-PQKE-----PVGCSKGGGPPREDVGAPLVTPSLLQMV 887 Query: 261 GLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTS 320 L + P GAP L P S +P +L R P+P Sbjct: 888 RLRSVGAPGGAPTPALGP--------SAPQKPLRRALSGRASPVPA-------------- 925 Query: 321 SLTHGAGQVLCGNPTKGLRER-RHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDF 379 P+ GL R + + E L +P P + P PA ++ F Sbjct: 926 -------------PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASF 972 Query: 380 LALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASE 439 + G R + RP+ Q VA R + E++ QA K+P +PP +A + Sbjct: 973 IFSKGSRKLQLE--RPVSPETQADLQRNLVAEL--RSISEQRPPQAPKKSPKAPPPVARK 1028 Query: 440 PS-GTSSQHLVPSPPKHPR------PRDSG--SSSPRWSTDLQSRGRRLRVLG 483 PS G P+ P +PR P +G + R +L G L+++G Sbjct: 1029 PSVGVPP----PASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENGGVLQLVG 1077 Score = 36.6 bits (83), Expect = 0.060 Identities = 50/199 (25%), Positives = 72/199 (36%), Gaps = 57/199 (28%) Query: 350 PPEQLPQHRPGDPAASTSTPEPDPADSSDFLAL--AGLRAWREHGVR------PLPYRHP 401 PP Q R ST A++SD L++ +G + R +R P P R Sbjct: 453 PPPQGGSGRGSPSGGST-------AEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTH 505 Query: 402 ESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDS 461 Q G P GP +P + + +P+ P P + SE +G + P PP Sbjct: 506 SLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAA-----PCPP-------- 552 Query: 462 GSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVL---RALEVASRLSPRA------ 512 SW PGL G + P R L +S S ++ Sbjct: 553 ------------------NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLP 594 Query: 513 -QGCPGPKPAPDAAARPPR 530 +G GP PA A+PP+ Sbjct: 595 PKGLAGP-PASPGKAQPPK 612 Score = 33.9 bits (76), Expect = 0.39 Identities = 52/207 (25%), Positives = 70/207 (33%), Gaps = 37/207 (17%) Query: 340 ERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYR 399 ER+ Q Q PP G A + P+PA+S W G+ P R Sbjct: 526 ERKQQPQLPRPPTT-----GGSEGAGAAPCPPNPANS-----------WVP-GLSPGGSR 568 Query: 400 HPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPR 459 P E ++P + ++ TP+ PP + P + + P P + R Sbjct: 569 RPPRSPERTLSP--------SSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLR 620 Query: 460 DSGSSSPRWSTDLQSRGRRLRVLGSWGP----GLGDGVAAVPVLRALEVASRLSPRAQGC 515 G+S T L S GP LGD P +V + SP Sbjct: 621 SPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPP---HPKVPAPFSP----- 672 Query: 516 PGPKPAPDAAARPPRAAELSHPSPVPT 542 P KP A P AA P PV T Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVST 699 >gi|237757312 synaptojanin 1 isoform c [Homo sapiens] Length = 1295 Score = 45.4 bits (106), Expect = 1e-04 Identities = 57/236 (24%), Positives = 79/236 (33%), Gaps = 36/236 (15%) Query: 311 EDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREP-----PEQLPQHRPGDPAAS 365 E+L P+ S + G G +P + + P P + P PG P+A Sbjct: 1023 EELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQ 1082 Query: 366 TSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQA 425 +S + PA PLP + P E P P R A Sbjct: 1083 SSPIDAQPAT-------------------PLPQKDPAQPLEPKRPP--PPRPVAPPTRPA 1121 Query: 426 EPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSW 485 P+ P PPS A P+ T + P P R + G S P L G Sbjct: 1122 PPQRPP-PPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP 1180 Query: 486 GPGLGDGVAAVPVLRALEVASRLSPRAQGCPG---------PKPAPDAAARPPRAA 532 GV + P A A RL+P +Q P+P AA PP+++ Sbjct: 1181 TIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSS 1236 Score = 31.2 bits (69), Expect = 2.5 Identities = 60/264 (22%), Positives = 85/264 (32%), Gaps = 37/264 (14%) Query: 214 NYRAEVRKLIPQLQVLDEVPAAHTGPPAPPRLSQDW-------------LAVKEAIKKGN 260 +Y AEV +L+PQ T P + PR S + A + Sbjct: 1017 DYSAEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTP 1076 Query: 261 GLP-----PLDCPRGAPIRRLDPELSLPETQSRASRPWPFSLLVRGGPLPEGLLSEDLAP 315 G P P+D P+ + DP + P R P P + R P P+ P Sbjct: 1077 GPPSAQSSPIDAQPATPLPQKDP--AQPLEPKRPPPPRPVAPPTRPAP-PQ-------RP 1126 Query: 316 EDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPAD 375 + + + + G P R+ +P Q PG ST+ P P Sbjct: 1127 PPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPR- 1185 Query: 376 SSDFLALAG-LRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPP 434 AG + A + H PESQ + + G +PE QA SS P Sbjct: 1186 -------AGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLP 1238 Query: 435 SLASEPSGTSSQHLVPSPPKHPRP 458 A P P P+P Sbjct: 1239 PPAQRLQEPLVPVAAPMPQSGPQP 1262 >gi|190684671 mitogen-activated protein kinase binding protein 1 isoform a [Homo sapiens] Length = 1508 Score = 45.4 bits (106), Expect = 1e-04 Identities = 92/393 (23%), Positives = 144/393 (36%), Gaps = 65/393 (16%) Query: 166 DLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQ 225 D EG ED G L P LA T + L P P +PR ++ E+ + Sbjct: 782 DKEG---EDEGTEEELPALPVLAKSTKKA----LASVPSPA--LPRSLSHW-EMSRAQES 831 Query: 226 LQVLDEVPAAHTGPPAPPRLSQDWLAVK----------EAIKKGNGLPPLDC-------P 268 + LD PAA+ GP R Q + + E + P D P Sbjct: 832 VGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGP 891 Query: 269 RGAPIRRLDPELSLPETQS---RASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHG 325 R L+ L+ + +AS+P + ++R EG+ ++DL P + + Sbjct: 892 RKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYP 951 Query: 326 AGQVLCGNPTKGLRERRHQCQAR------EPPEQLPQHRPGDPAAST-------STPE-- 370 NPT E + Q AR P + + D A S S+PE Sbjct: 952 EPS---DNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHP 1008 Query: 371 PDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTP 430 + ++S++ L++ G+ + E P E ++EG + P+G + + P+TP Sbjct: 1009 TEDSESTEPLSVDGISSDLE---EPAEGDEEEEEEEGGMGPYG--------LQEGSPQTP 1057 Query: 431 SSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLG 490 L +S +P + P +S S S R+ +Q+R R S L Sbjct: 1058 DQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALM 1117 Query: 491 DGVAAVPVLRALEVASRLSPRAQGCPGPKPAPD 523 A VP AS PR G P P+ Sbjct: 1118 SRPAQVP------QASGEQPRGNGANPPGAPPE 1144 >gi|190684677 mitogen-activated protein kinase binding protein 1 isoform b [Homo sapiens] Length = 1514 Score = 45.4 bits (106), Expect = 1e-04 Identities = 92/393 (23%), Positives = 144/393 (36%), Gaps = 65/393 (16%) Query: 166 DLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQ 225 D EG ED G L P LA T + L P P +PR ++ E+ + Sbjct: 788 DKEG---EDEGTEEELPALPVLAKSTKKA----LASVPSPA--LPRSLSHW-EMSRAQES 837 Query: 226 LQVLDEVPAAHTGPPAPPRLSQDWLAVK----------EAIKKGNGLPPLDC-------P 268 + LD PAA+ GP R Q + + E + P D P Sbjct: 838 VGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGP 897 Query: 269 RGAPIRRLDPELSLPETQS---RASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHG 325 R L+ L+ + +AS+P + ++R EG+ ++DL P + + Sbjct: 898 RKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYP 957 Query: 326 AGQVLCGNPTKGLRERRHQCQAR------EPPEQLPQHRPGDPAAST-------STPE-- 370 NPT E + Q AR P + + D A S S+PE Sbjct: 958 EPS---DNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHP 1014 Query: 371 PDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTP 430 + ++S++ L++ G+ + E P E ++EG + P+G + + P+TP Sbjct: 1015 TEDSESTEPLSVDGISSDLE---EPAEGDEEEEEEEGGMGPYG--------LQEGSPQTP 1063 Query: 431 SSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLG 490 L +S +P + P +S S S R+ +Q+R R S L Sbjct: 1064 DQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALM 1123 Query: 491 DGVAAVPVLRALEVASRLSPRAQGCPGPKPAPD 523 A VP AS PR G P P+ Sbjct: 1124 SRPAQVP------QASGEQPRGNGANPPGAPPE 1150 >gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sapiens] Length = 735 Score = 44.7 bits (104), Expect = 2e-04 Identities = 61/210 (29%), Positives = 77/210 (36%), Gaps = 18/210 (8%) Query: 339 RERRHQCQAREP--PEQLPQHRPGDPAASTSTPEPD----PADSSDFLALA-GLRAWREH 391 +ER H Q EP PE PQ G A + P+ PA + +L R W Sbjct: 27 KERGHPAQRPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLG 86 Query: 392 GVRPLPYRHPESQQEGAVAPWGP---RRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHL 448 G +P G P G +PEE P+ P P ++E G + Q Sbjct: 87 GAKPAEDTSLGPGVPGTGEPAGEIWYNPIPEEDPRPPAPEPPGPQPG-SAESEGLAPQGA 145 Query: 449 VP-SPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLG-DGVAAVPVLRALEVAS 506 P SPP S + R S ++ R L GP G + A P A V S Sbjct: 146 APASPPTKASRTKSPGPARRLSIKMKKLPELRRRLSLRGPRAGRERERAAP---AGSVIS 202 Query: 507 RLS-PRAQGCPGPKPAPDAAARPPRAAELS 535 R + G PGP P R PRA LS Sbjct: 203 RYHLDSSVGGPGPAAGP-GGTRSPRAGYLS 231 Score = 31.6 bits (70), Expect = 1.9 Identities = 38/139 (27%), Positives = 52/139 (37%), Gaps = 21/139 (15%) Query: 419 EEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGS-------SSPRWSTD 471 +E+ H A+ PS P P G+ + PS P+ R G+ SS RW Sbjct: 27 KERGHPAQRPEPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSSRRWVLG 86 Query: 472 LQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKP--------APD 523 ++ LG PG G+ + E R P A PGP+P AP Sbjct: 87 -GAKPAEDTSLGPGVPGTGEPAGEIWYNPIPEEDPR--PPAPEPPGPQPGSAESEGLAPQ 143 Query: 524 AAA---RPPRAAELSHPSP 539 AA P +A+ P P Sbjct: 144 GAAPASPPTKASRTKSPGP 162 >gi|40556370 PHD finger protein 15 [Homo sapiens] Length = 790 Score = 44.3 bits (103), Expect = 3e-04 Identities = 46/173 (26%), Positives = 68/173 (39%), Gaps = 11/173 (6%) Query: 286 QSRASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQC 345 ++ A WP + R P P GLLSE+L ++ T + G+P + R R Sbjct: 543 ENMAMSEWPLNNGHREDPAP-GLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLP 601 Query: 346 QAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQ 405 ++PP PQ PG S +TP+ P + A +G + + R P R Sbjct: 602 AKKKPPPPPPQDGPG----SRTTPDKAPKKTWGQDAGSG-KGGQGPPTRKPPRRTSSHLP 656 Query: 406 EGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRP 458 A P E P+TP S+A++ S VP P P+P Sbjct: 657 SSPAAGDCPILATPESPPPLAPETPDEAASVAAD-----SDVQVPGPAASPKP 704 Score = 29.3 bits (64), Expect = 9.6 Identities = 34/149 (22%), Positives = 49/149 (32%), Gaps = 22/149 (14%) Query: 405 QEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSS 464 ++ ++ P P R + K P PP G S+ PK +D+GS Sbjct: 581 RDPSLRPGDPARKARGRTRLPAKKKPPPPPP----QDGPGSRTTPDKAPKKTWGQDAGSG 636 Query: 465 SPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQG---------- 514 + RR P GD P+L E L+P Sbjct: 637 KGGQGPPTRKPPRRTSSHLPSSPAAGD----CPILATPESPPPLAPETPDEAASVAADSD 692 Query: 515 --CPGP--KPAPDAAARPPRAAELSHPSP 539 PGP P P RPPR ++++ P Sbjct: 693 VQVPGPAASPKPLGRLRPPRESKVTRRLP 721 >gi|116268109 nucleotide-binding oligomerization domains 27 [Homo sapiens] Length = 1866 Score = 44.3 bits (103), Expect = 3e-04 Identities = 50/169 (29%), Positives = 73/169 (43%), Gaps = 29/169 (17%) Query: 94 NLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADL------DGIASLPALKELYASY 147 +L L LN S L L + + LQ L L R + D+ + + + +L+EL S+ Sbjct: 1556 DLSHLLLNSSTLALLTHRLSQMTCLQSLRLNRNSIGDVGCCHLSEALRAATSLEELDLSH 1615 Query: 148 NNISDLSPLCL------LEQLEVLDLEGNSVEDLGQVRY---LQLCPRLAMLTLEGNLVC 198 N I D L L +L +DL GNS+ G V+ L LC RL L L N + Sbjct: 1616 NQIGDAGVQHLATILPGLPELRKIDLSGNSISSAGGVQLAESLVLCRRLEELMLGCNALG 1675 Query: 199 LQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLDEVPAAHTGPPAPPRLSQ 247 A G ++P+ L+VL +P +H GP L+Q Sbjct: 1676 DPTALGLAQELPQ-------------HLRVL-HLPFSHLGPGGALSLAQ 1710 >gi|223718151 leucine rich transmembrane and 0-methyltransferase domain containing isoform 2 [Homo sapiens] Length = 158 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 9/86 (10%) Query: 119 QVLWLARCGLADLDGIASLPA--------LKELYASYNNISDLSP-LCLLEQLEVLDLEG 169 Q LWL L DL + + L + S+N+++ + P L L VL L G Sbjct: 52 QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111 Query: 170 NSVEDLGQVRYLQLCPRLAMLTLEGN 195 NS++ LG+V L + PRL LTL GN Sbjct: 112 NSIQRLGEVNKLAVLPRLRSLTLHGN 137 >gi|21687175 leucine rich transmembrane and 0-methyltransferase domain containing isoform 1 [Homo sapiens] Length = 192 Score = 43.9 bits (102), Expect = 4e-04 Identities = 31/86 (36%), Positives = 43/86 (50%), Gaps = 9/86 (10%) Query: 119 QVLWLARCGLADLDGIASLPA--------LKELYASYNNISDLSP-LCLLEQLEVLDLEG 169 Q LWL L DL + + L + S+N+++ + P L L VL L G Sbjct: 52 QSLWLNNNVLNDLRDFNQVASQLLEHPENLAWIDLSFNDLTSIDPVLTTFFNLSVLYLHG 111 Query: 170 NSVEDLGQVRYLQLCPRLAMLTLEGN 195 NS++ LG+V L + PRL LTL GN Sbjct: 112 NSIQRLGEVNKLAVLPRLRSLTLHGN 137 >gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family, member B [Homo sapiens] Length = 251 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/138 (31%), Positives = 59/138 (42%), Gaps = 17/138 (12%) Query: 95 LDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNI-SDL 153 LD K N G + L +L+ L L GL + + LP LK+L S N I L Sbjct: 24 LDNCKSND---GKIEGLTAEFVNLEFLSLINVGLISVSNLPKLPKLKKLELSENRIFGGL 80 Query: 154 SPLC-LLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGNLVCLQPAPGPTNKVPRG 212 L L L L+L GN ++D+ + L+ L CL+ +V Sbjct: 81 DMLAEKLPNLTHLNLSGNKLKDISTLEPLK------------KLECLKSLDLFNCEVTNL 128 Query: 213 YNYRAEVRKLIPQLQVLD 230 +YR V KL+PQL LD Sbjct: 129 NDYRESVFKLLPQLTYLD 146 Score = 30.0 bits (66), Expect = 5.6 Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 8/118 (6%) Query: 80 TREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGL-ADLDGIAS-L 137 + +G + NL+ L L L S+ +L L L+ L L+ + LD +A L Sbjct: 29 SNDGKIEGLTAEFVNLEFLSLINVGLISVSNL-PKLPKLKKLELSENRIFGGLDMLAEKL 87 Query: 138 PALKELYASYNNISDLS---PLCLLEQLEVLDLEGNSVEDLGQVR--YLQLCPRLAML 190 P L L S N + D+S PL LE L+ LDL V +L R +L P+L L Sbjct: 88 PNLTHLNLSGNKLKDISTLEPLKKLECLKSLDLFNCEVTNLNDYRESVFKLLPQLTYL 145 >gi|24308207 leucine rich repeat containing 47 [Homo sapiens] Length = 583 Score = 43.9 bits (102), Expect = 4e-04 Identities = 39/110 (35%), Positives = 53/110 (48%), Gaps = 8/110 (7%) Query: 92 LPNLDQLKLNGSHLGSL-RDLGTSLGHLQVLWLARCGL----ADLDGIASLPALKELYAS 146 LP L L L+G+ L L DL LQ L L L A+L +LP L EL A+ Sbjct: 128 LPQLQSLNLSGNRLRELPADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSELAAA 187 Query: 147 YNNISDLSP-LCLLEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEGN 195 N + +LSP + L L+ LDL N + ++ L CP+L + GN Sbjct: 188 DNCLRELSPDIAHLASLKTLDLSNNQLSEI--PAELADCPKLKEINFRGN 235 Score = 30.8 bits (68), Expect = 3.3 Identities = 51/170 (30%), Positives = 65/170 (38%), Gaps = 49/170 (28%) Query: 92 LPNLDQLKLNGSHLGSLRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNIS 151 LP L L+++G GSLR G L LP L L N + Sbjct: 49 LPLLHYLEVSGC--GSLRAPGPGLAQ------------------GLPQLHSLVLRRNALG 88 Query: 152 D-LSP-LCLLEQLEVLDLEGNSVEDLGQVRYLQLC-----PRLAMLTLEGNLVCLQPAPG 204 LSP L L L VLDL GN++E L + L P+L L L GN + P Sbjct: 89 PGLSPELGPLPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRLRELP--- 145 Query: 205 PTNKVPRGYNYRAEVRKLIPQLQ-------VLDEVPAAHTGPPAPPRLSQ 247 A++ + P+LQ LD PA P A P LS+ Sbjct: 146 ------------ADLARCAPRLQSLNLTGNCLDSFPAELFRPGALPLLSE 183 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 43.9 bits (102), Expect = 4e-04 Identities = 58/182 (31%), Positives = 71/182 (39%), Gaps = 31/182 (17%) Query: 363 AASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAP-WGPRRVPEEQ 421 AA+T+ P P PA G RA R PL P AVAP GPRR P Sbjct: 154 AAATAPPSPGPAQP-------GPRAQR---AAPLAAPPPAPAAPPAVAPPAGPRRAPPPA 203 Query: 422 VHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRV 481 V EP P PP + P Q P PP+ P + G+ + S +R Sbjct: 204 VAAREPPLP-PPPQPPAPP-----QQQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRY 257 Query: 482 L-GSWGPG-----------LGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPP 529 L GS G G L + AA L + + PR PG P P A+ARP Sbjct: 258 LGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDR-PGRAP-PAASARPS 315 Query: 530 RA 531 R+ Sbjct: 316 RS 317 Score = 32.0 bits (71), Expect = 1.5 Identities = 33/132 (25%), Positives = 44/132 (33%), Gaps = 11/132 (8%) Query: 411 PWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWST 470 P PR P A P TP+ PP A + +P + PR + +++P Sbjct: 112 PRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAA--------APARAPRAAAAAATAPPSPG 163 Query: 471 DLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGC-PGPKPAPDAAARPP 529 Q R R P AA P + R P A P P P PP Sbjct: 164 PAQPGPRAQRAAPLAAP--PPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPP 221 Query: 530 RAAELSHPSPVP 541 + + P P P Sbjct: 222 QQQQPPPPQPQP 233 Score = 30.4 bits (67), Expect = 4.3 Identities = 29/118 (24%), Positives = 38/118 (32%), Gaps = 8/118 (6%) Query: 427 PKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWG 486 P+ ++PP+ P G + +PP P P + + R Sbjct: 102 PRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPS 161 Query: 487 PGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAAR---PPRAAELSHPSPVP 541 PG A P RA A +P P AP A R PP A P P P Sbjct: 162 PG-----PAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.5 bits (101), Expect = 5e-04 Identities = 84/323 (26%), Positives = 108/323 (33%), Gaps = 63/323 (19%) Query: 224 PQLQVLDEVPAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLP 283 P LQ L PA PP+ S + +A PPL P P + P L+LP Sbjct: 349 PSLQTLPSPPAT---PPSQATTSLGSPTL-QATHSFLPSPPLS-PLATPPPQAPPALALP 403 Query: 284 ETQSRASRPW--PFSLLVRGGPLPEGLLSEDL--APEDNTSSLTHGAGQVLCGNPTKGLR 339 Q+ S P P S L P L+ L AP S Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS------------------ 445 Query: 340 ERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYR 399 PP Q P P P S S P A S LA L+ V P P Sbjct: 446 ----------PPVQAPFSPPASPPVSPSATPPSQAPPS--LAAPPLQ------VPPSPPA 487 Query: 400 HPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPR 459 P P P + + A+P P +PP+LA+ P +PSPP Sbjct: 488 SPPMSPSATPPPQAPPPLAAPPLQLAKP-PPQAPPALATPP-----LQALPSPP------ 535 Query: 460 DSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQG-CPGP 518 +S P + S + L + P V A P+L+ + + SP Q P Sbjct: 536 ---ASFPGQAPFSPSASLPMSPLAT-PPPQAPPVLAAPLLQ-VPPSPPASPTLQAPRRPP 590 Query: 519 KPAPDAAARPPRAAELSHPSPVP 541 P PD + PR P P P Sbjct: 591 TPGPDTSVSGPRLTLALAPGPPP 613 Score = 37.7 bits (86), Expect = 0.027 Identities = 58/203 (28%), Positives = 76/203 (37%), Gaps = 40/203 (19%) Query: 348 REPPEQLPQHRP-GDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQE 406 R PP + P P ++ T P P L GLR E V + E+ + Sbjct: 102 RAPPAKNTSPGPVSSPGRASGTTRPGP------LGQKGLRISAEETVAR--GKATEAPKR 153 Query: 407 GAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPR-----PRDS 461 A++ G RR P TPS + S +GT P+P PR PR S Sbjct: 154 SALSA-GARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208 Query: 462 GSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVA-------SRLSPRAQG 514 SS+ ST S R R P G G+ P R+L + +R P A+G Sbjct: 209 VSSASEHSTTEPSPAARRR------PSAGGGLQR-PASRSLSSSATPLSSPARSGPSARG 261 Query: 515 CP-------GPKPAPDAAARPPR 530 P PKP A RPP+ Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQ 284 Score = 37.7 bits (86), Expect = 0.027 Identities = 56/220 (25%), Positives = 74/220 (33%), Gaps = 50/220 (22%) Query: 233 PAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRP 292 P A P APP L+ L V + P L PR P D +S P Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPAS---PTLQAPRRPPTPGPDTSVSGPR-------- 602 Query: 293 WPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPE 352 +L + GP P P + SS G L G H A PE Sbjct: 603 --LTLALAPGPPPP--------PSRSPSSTLSGPD--LAG----------HSSSATSTPE 640 Query: 353 QLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPW 412 +L + G + ++P PD LA AW PL +R GA PW Sbjct: 641 ELRGYDSGPEGGAAASPPPDAE-----LAACHPAAWSRGPAPPLAFR----GAPGAPLPW 691 Query: 413 GPRRVPEE-----QVHQAEPKTPSSPPSLASEPS---GTS 444 P P +++ E ++P A +P GTS Sbjct: 692 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731 Score = 33.1 bits (74), Expect = 0.66 Identities = 80/322 (24%), Positives = 102/322 (31%), Gaps = 56/322 (17%) Query: 269 RGAPIRRLDP-ELSLPETQSRASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAG 327 R P + P +S P S +RP P E + S+L+ GA Sbjct: 102 RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR 161 Query: 328 QVLCGNPTKGLRE----RRHQCQAREP--PEQLPQHRPGDP----------AASTSTPEP 371 + G PT G RR + E P P RP P A+ ST EP Sbjct: 162 RDTSG-PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220 Query: 372 DPADSSDFLALAGLR--AWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEEQVHQAEPKT 429 PA A GL+ A R P P A R P H ++PK Sbjct: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA------RGTPRAPAHPSQPKP 274 Query: 430 PS---------SPPS---------LASEPSGTSSQHLV---PSPPKHPRPRDSGSSSPRW 468 +PP L+S P T S +PP P S S + + Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334 Query: 469 STDLQ------SRGRRLRVLGS---WGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPK 519 +T L S L+ L S P P L+A P + P Sbjct: 335 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394 Query: 520 PAPDAAARPPRAAELSHPSPVP 541 AP A A PP A S P+ P Sbjct: 395 QAPPALALPPLQAPPSPPASPP 416 Score = 30.0 bits (66), Expect = 5.6 Identities = 62/263 (23%), Positives = 87/263 (33%), Gaps = 74/263 (28%) Query: 280 LSLPETQSRASRPWPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLR 339 L P ++S +S P S R GP G P KGL Sbjct: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP---------------KGL- 277 Query: 340 ERRHQCQAREPPEQLPQHRPGDPAAS--TSTPEPDPADSSDFLALAGLRAWREHGVRPLP 397 QA PP+ P + PA +S+P P+ S A L++ + P Sbjct: 278 ------QALRPPQVTPPRKDAAPALGPLSSSPLATPSPS------AALQSQAPPTLPATP 325 Query: 398 YRHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPR 457 + + Q P P +PS+PPSL + +PSPP P Sbjct: 326 HSSSLTCQLATPLPLAP-------------PSPSAPPSLQT----------LPSPPATPP 362 Query: 458 PRDSGS-SSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCP 516 + + S SP L+ S+ P P L L +P A P Sbjct: 363 SQATTSLGSP-----------TLQATHSFLPS--------PPLSPLATPPPQAPPALALP 403 Query: 517 GPKPAPDAAARPPRAAELSHPSP 539 P AP + P + L+ PSP Sbjct: 404 -PLQAPPSPPASPPLSPLATPSP 425 Score = 29.3 bits (64), Expect = 9.6 Identities = 35/117 (29%), Positives = 44/117 (37%), Gaps = 29/117 (24%) Query: 437 ASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGP--------- 487 A P+ + L P PP PRP + + LRVLG+ G Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPA------------ALRVLGAAGAVGRKPLAER 61 Query: 488 GLGDGVAAVPVLRALEVASRLSP-RAQGCPGPKPA--PDAAARPPRAAELSHPSPVP 541 G G A +P E A R P R+ G PA P A+ R RA + SP P Sbjct: 62 AGGIGGATIP-----ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 43.5 bits (101), Expect = 5e-04 Identities = 84/323 (26%), Positives = 108/323 (33%), Gaps = 63/323 (19%) Query: 224 PQLQVLDEVPAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLP 283 P LQ L PA PP+ S + +A PPL P P + P L+LP Sbjct: 310 PSLQTLPSPPAT---PPSQATTSLGSPTL-QATHSFLPSPPLS-PLATPPPQAPPALALP 364 Query: 284 ETQSRASRPW--PFSLLVRGGPLPEGLLSEDL--APEDNTSSLTHGAGQVLCGNPTKGLR 339 Q+ S P P S L P L+ L AP S Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS------------------ 406 Query: 340 ERRHQCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYR 399 PP Q P P P S S P A S LA L+ V P P Sbjct: 407 ----------PPVQAPFSPPASPPVSPSATPPSQAPPS--LAAPPLQ------VPPSPPA 448 Query: 400 HPESQQEGAVAPWGPRRVPEEQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPR 459 P P P + + A+P P +PP+LA+ P +PSPP Sbjct: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKP-PPQAPPALATPP-----LQALPSPP------ 496 Query: 460 DSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQG-CPGP 518 +S P + S + L + P V A P+L+ + + SP Q P Sbjct: 497 ---ASFPGQAPFSPSASLPMSPLAT-PPPQAPPVLAAPLLQ-VPPSPPASPTLQAPRRPP 551 Query: 519 KPAPDAAARPPRAAELSHPSPVP 541 P PD + PR P P P Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPP 574 Score = 38.9 bits (89), Expect = 0.012 Identities = 82/335 (24%), Positives = 104/335 (31%), Gaps = 56/335 (16%) Query: 237 TGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRPWPFS 296 T P + PR + A +G PP P+ S P S +RP P Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPV-------SSPGRASGTTRPGPLG 121 Query: 297 LLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRE----RRHQCQAREP-- 350 E + S+L+ GA + G PT G RR + E Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTEVGL 180 Query: 351 PEQLPQHRPGDP----------AASTSTPEPDPADSSDFLALAGLR--AWREHGVRPLPY 398 P P RP P A+ ST EP PA A GL+ A R P Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 Query: 399 RHPESQQEGAVAPWGPRRVPEEQVHQAEPKTPS---------SPPSLASEPSG---TSSQ 446 P A R P H ++PK +PP + P+ +SS Sbjct: 241 SSPARSGPSA------RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294 Query: 447 HLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVAS 506 PSP P P S S + LGS P L+A Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS------------PTLQATHSFL 342 Query: 507 RLSPRAQGCPGPKPAPDAAARPPRAAELSHPSPVP 541 P + P AP A A PP A S P+ P Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 377 Score = 37.7 bits (86), Expect = 0.027 Identities = 56/220 (25%), Positives = 74/220 (33%), Gaps = 50/220 (22%) Query: 233 PAAHTGPPAPPRLSQDWLAVKEAIKKGNGLPPLDCPRGAPIRRLDPELSLPETQSRASRP 292 P A P APP L+ L V + P L PR P D +S P Sbjct: 515 PLATPPPQAPPVLAAPLLQVPPSPPAS---PTLQAPRRPPTPGPDTSVSGPR-------- 563 Query: 293 WPFSLLVRGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPE 352 +L + GP P P + SS G L G H A PE Sbjct: 564 --LTLALAPGPPPP--------PSRSPSSTLSGPD--LAG----------HSSSATSTPE 601 Query: 353 QLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPW 412 +L + G + ++P PD LA AW PL +R GA PW Sbjct: 602 ELRGYDSGPEGGAAASPPPDAE-----LAACHPAAWSRGPAPPLAFR----GAPGAPLPW 652 Query: 413 GPRRVPEE-----QVHQAEPKTPSSPPSLASEPS---GTS 444 P P +++ E ++P A +P GTS Sbjct: 653 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 692 Score = 30.0 bits (66), Expect = 5.6 Identities = 47/181 (25%), Positives = 63/181 (34%), Gaps = 47/181 (25%) Query: 360 GDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPE 419 G P A +P P GL+A R V P P A+ P P Sbjct: 252 GTPRAPAHPSQPKPK---------GLQALRPPQVTP-----PRKDAAPALGPLSSS--PL 295 Query: 420 EQVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGS-SSPRWSTDLQSRGRR 478 + P +PS+PPSL + +PSPP P + + S SP Sbjct: 296 ATPSPSAPPSPSAPPSLQT----------LPSPPATPPSQATTSLGSP-----------T 334 Query: 479 LRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSHPS 538 L+ S+ P P L L +P A P P AP + P + L+ PS Sbjct: 335 LQATHSFLPS--------PPLSPLATPPPQAPPALALP-PLQAPPSPPASPPLSPLATPS 385 Query: 539 P 539 P Sbjct: 386 P 386 >gi|238859651 pleckstrin homology domain containing family A member 4 isoform 1 [Homo sapiens] Length = 779 Score = 42.7 bits (99), Expect = 8e-04 Identities = 51/175 (29%), Positives = 66/175 (37%), Gaps = 36/175 (20%) Query: 306 EGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRHQCQAREPPEQLPQHRPGDPAAS 365 EG +SE +PE S G ++L +PT L +AR P P RP P Sbjct: 188 EGRISE--SPEVTRLSRGRGRPRLLTPSPTTDLHSGLQMRRARSPDLFTPLSRPPSPL-- 243 Query: 366 TSTPEP-------DPADSSDF---------LALAGLRAWREHGVR-------PLPYRHPE 402 S P P PA S D L+ +R + G + P P R P Sbjct: 244 -SLPRPRSAPARRPPAPSGDTAPPARPHTPLSRIDVRPPLDWGPQRQTLSRPPTPRRGPP 302 Query: 403 SQQEGAVAPWGPR---RVPEEQVHQAEPKTPSSPPSLASEPSGT-SSQHLVPSPP 453 S+ G P P+ + P Q H P PP P GT +S L+P PP Sbjct: 303 SEAGGGKPPRSPQHWSQEPRTQAHSGSPTYLQLPP----RPPGTRASMVLLPGPP 353 >gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo sapiens] Length = 757 Score = 42.7 bits (99), Expect = 8e-04 Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 6/109 (5%) Query: 91 HLPNLDQLKLNGSHLGSLRDLG-TSLGHLQVLWLARCGLADL--DGIASLPALKELYASY 147 H+P L L L G+H+ +LR+L S +L VL + + + L + A L L EL Sbjct: 245 HMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGS 304 Query: 148 NNISDLSPLCL--LEQLEVLDLEGNSVEDLGQVRYLQLCPRLAMLTLEG 194 N I +L PL L++L L+L N ++ + Q +L L+LEG Sbjct: 305 NKIENLPPLIFKDLKELSQLNLSYNPIQKI-QANQFDYLVKLKSLSLEG 352 >gi|117414154 sodium channel associated protein 2 isoform b [Homo sapiens] Length = 939 Score = 42.7 bits (99), Expect = 8e-04 Identities = 36/102 (35%), Positives = 51/102 (50%), Gaps = 11/102 (10%) Query: 133 GIASLPALKELYASYNNISDLSPLCLLE----QLEVLDLEGNSVEDLGQVRYLQLCPRLA 188 G+ L L L SYN+I DLS L L +L +DL N ++ + + LQ L Sbjct: 11 GLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHL--LQCMVGLH 68 Query: 189 MLTLEGNLVCLQPAPGPTNKVPRGYNYRAEVRKLIPQLQVLD 230 LT NL+ + G N V R YRA + + +PQL++LD Sbjct: 69 FLT---NLILEKD--GDDNPVCRLPGYRAVILQTLPQLRILD 105 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 42.4 bits (98), Expect = 0.001 Identities = 49/176 (27%), Positives = 64/176 (36%), Gaps = 13/176 (7%) Query: 362 PAASTS-TPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPESQQEGAVAPWGPRRVPEE 420 P+ STS T + +P SD + G W P P P S+ + GP +P Sbjct: 525 PSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPC--PSPSSRPPSRYQS-----GPNSLPPR 577 Query: 421 QVHQAEPKTPSSPPSLASEPSGTSSQHLVPSPPKHPRPRDSGSSSPRWSTDLQSRGRRLR 480 P PS PPS S P S H P+P R S PR S Q R R Sbjct: 578 AATPTRP--PSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGPPRMSPKAQRHPRNHR 635 Query: 481 VLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQGCPGPKPAPDAAARPPRAAELSH 536 V G + G+ V E A+ P A+ P + PR + +H Sbjct: 636 VSAGRG-SISSGLEFVSHNPPSEAAT--PPVARTSPSGGTWSSVVSGVPRLSPKTH 688 >gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sapiens] Length = 360 Score = 42.4 bits (98), Expect = 0.001 Identities = 34/134 (25%), Positives = 70/134 (52%), Gaps = 3/134 (2%) Query: 48 QLVEEYLSPARLQALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGS 107 +L + +L ++ + + +L ++ LE+ R ++ N L NL+ L L + + Sbjct: 165 RLKKLFLVNNKISKIENLSNLHQLQMLELG-SNRIRAIENIDT-LTNLESLFLGKNKITK 222 Query: 108 LRDLGTSLGHLQVLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDL 167 L++L +L +L VL + L ++G+ +L L+ELY S+N I + L +L +LD+ Sbjct: 223 LQNLD-ALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDI 281 Query: 168 EGNSVEDLGQVRYL 181 N ++ + + +L Sbjct: 282 ASNRIKKIENISHL 295 Score = 42.0 bits (97), Expect = 0.001 Identities = 31/119 (26%), Positives = 60/119 (50%), Gaps = 9/119 (7%) Query: 60 QALARVDDLRLVRTLEMCVDTREGSLGNFGVHLPNLDQLKLNGSHLGSLRDLGTSLGHLQ 119 + L +V L L + L C++ E L +L +L L + + + +L +L L+ Sbjct: 95 EVLKKVKTLCLRQNLIKCIENLE--------ELQSLRELDLYDNQIKKIENL-EALTELE 145 Query: 120 VLWLARCGLADLDGIASLPALKELYASYNNISDLSPLCLLEQLEVLDLEGNSVEDLGQV 178 +L ++ L +++G+ L LK+L+ N IS + L L QL++L+L N + + + Sbjct: 146 ILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENI 204 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 42.4 bits (98), Expect = 0.001 Identities = 91/389 (23%), Positives = 138/389 (35%), Gaps = 72/389 (18%) Query: 201 PAPGPTNKVPRGYNYRA-----EVRKLIP-------QLQVLDEVPAAHTGP--------- 239 P GP++ P G E R IP +LQ L PA P Sbjct: 253 PGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASEST 312 Query: 240 -PAPPR------LSQDWLAVKEAIKKG--NGLP---PLDCPRGAPIRRLDPELSLPETQS 287 PAPP L Q+ L V++A NG P+ PRG P P P Sbjct: 313 TPAPPTPRPRSSLQQENL-VEQAGSSSLVNGRLHELPVPKPRGTP----KPSEGTPAP-- 365 Query: 288 RASRPWPFSLLV----RGGPLPEGLLSEDLAPEDNTSSLTHGAGQVLCGNPTKGLRERRH 343 R PW + + PLP S +D+ G +V +PT L + + Sbjct: 366 RKDPPWITLVQAEPKKKPAPLPPSS-SPGPPSQDSRQVENGGTEEVAQPSPTASLESKPY 424 Query: 344 QCQAREPPEQLPQHRPGDPAASTSTPEPDPADSSDFLALAGLRAWREHGVRPLPYRHPES 403 E E + P P+ +TS P + L W +G+ P + Sbjct: 425 N-PFEEEEEDKEEEAPAAPSLATSPALGHPESTPK-----SLHPW--YGITPTSSPKTKK 476 Query: 404 QQEGAVAPWGPRRVPEEQVHQAEPKTPSSPP-----SLASEPSGTSSQHLVPSPPKHPR- 457 + P + ++ +EP + + P SL+SE + ++ + PP P+ Sbjct: 477 RPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKS 536 Query: 458 ---PRDSGSSSPRWSTDLQSRGRRLRVLGSWGPGLGDGVAAVPVLRALEVASRLSPRAQG 514 P +P L + L S G + V +P + + L+PR +G Sbjct: 537 SSEPAVHAPGTPGNPVSLSTNSS----LASSGELVEPRVEQMP-----QASPGLAPRTRG 587 Query: 515 CPGPKPA-PDAAARPPRAAELSHPSPVPT 542 GP+PA P + A P + SPVP+ Sbjct: 588 SSGPQPAKPCSGATPTPLLLVGDRSPVPS 616 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.135 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,030,307 Number of Sequences: 37866 Number of extensions: 1745223 Number of successful extensions: 10694 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 104 Number of HSP's successfully gapped in prelim test: 717 Number of HSP's that attempted gapping in prelim test: 8510 Number of HSP's gapped (non-prelim): 2451 length of query: 542 length of database: 18,247,518 effective HSP length: 107 effective length of query: 435 effective length of database: 14,195,856 effective search space: 6175197360 effective search space used: 6175197360 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.