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Search of human proteins with 39930343
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|39930343 transmembrane and coiled-coil domain family 1
isoform b [Homo sapiens]
(329 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|39930343 transmembrane and coiled-coil domain family 1 isofor... 637 0.0
gi|190014612 transmembrane and coiled-coil domain family 1 isofo... 637 0.0
gi|190014610 transmembrane and coiled-coil domain family 1 isofo... 637 0.0
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 391 e-109
gi|188497714 transmembrane and coiled-coil domain family 3 [Homo... 286 2e-77
gi|4503177 testis expressed 28 [Homo sapiens] 122 3e-28
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 47 2e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 46 4e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 46 4e-05
gi|53729363 leucine rich repeat and sterile alpha motif containi... 46 5e-05
gi|53729361 leucine rich repeat and sterile alpha motif containi... 46 5e-05
gi|53729359 leucine rich repeat and sterile alpha motif containi... 46 5e-05
gi|219555718 synaptonemal complex central element protein 1 isof... 44 2e-04
gi|219555716 synaptonemal complex central element protein 1 isof... 44 2e-04
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 44 2e-04
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 44 2e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 44 3e-04
gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 44 3e-04
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 44 3e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 43 3e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 43 4e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 42 0.001
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 42 0.001
gi|81295809 pericentrin [Homo sapiens] 42 0.001
gi|187761324 shootin1 isoform a [Homo sapiens] 42 0.001
gi|50511340 shootin1 isoform b [Homo sapiens] 42 0.001
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 42 0.001
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 41 0.001
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 41 0.001
gi|18640754 synaptonemal complex central element protein 1 isofo... 41 0.001
>gi|39930343 transmembrane and coiled-coil domain family 1 isoform b
[Homo sapiens]
Length = 329
Score = 637 bits (1643), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD
Sbjct: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
Query: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA
Sbjct: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
Query: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR
Sbjct: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
Query: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL
Sbjct: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
Query: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST
Sbjct: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
Query: 301 LFLVVFIAFLWKHWDALFSYVERFFSSPR 329
LFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 301 LFLVVFIAFLWKHWDALFSYVERFFSSPR 329
>gi|190014612 transmembrane and coiled-coil domain family 1 isoform
c [Homo sapiens]
Length = 539
Score = 637 bits (1643), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD
Sbjct: 211 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 270
Query: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA
Sbjct: 271 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 330
Query: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR
Sbjct: 331 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 390
Query: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL
Sbjct: 391 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
Query: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST
Sbjct: 451 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 510
Query: 301 LFLVVFIAFLWKHWDALFSYVERFFSSPR 329
LFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 511 LFLVVFIAFLWKHWDALFSYVERFFSSPR 539
>gi|190014610 transmembrane and coiled-coil domain family 1 isoform
a [Homo sapiens]
Length = 653
Score = 637 bits (1643), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD
Sbjct: 325 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 384
Query: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA
Sbjct: 385 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 444
Query: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR
Sbjct: 445 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 504
Query: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL
Sbjct: 505 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 564
Query: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST
Sbjct: 565 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 624
Query: 301 LFLVVFIAFLWKHWDALFSYVERFFSSPR 329
LFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 625 LFLVVFIAFLWKHWDALFSYVERFFSSPR 653
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 391 bits (1004), Expect = e-109
Identities = 210/327 (64%), Positives = 250/327 (76%), Gaps = 8/327 (2%)
Query: 1 MHQGLKDVGAKV----TGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKF 56
M QGLKDVGA V +GF GVV+ VKG S SQATH+A VVSKPRE ASLIRNKF
Sbjct: 380 MQQGLKDVGANVRAGISGFGGGVVEGVKGSLSGLSQATHTA---VVSKPREFASLIRNKF 436
Query: 57 GSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGI 116
GSADNI +LKD LE+G ++A +AL + SSPKYGS+++CSSA++ S GA S +G
Sbjct: 437 GSADNIAHLKDPLEDGPPEEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAG 496
Query: 117 AVGA-SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQ 175
GA S K+N L DALL E++EI+E Q+ LE+S E LK QRDY+ + Q LQ
Sbjct: 497 PGGALGSPKSNALYGAPGNLDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQ 556
Query: 176 EERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRI 235
EERYR ERLEEQLNDLTELHQNE+ NLKQELASMEEK+AYQSYERARDIQEA+E+C TR+
Sbjct: 557 EERYRYERLEEQLNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRV 616
Query: 236 SKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRN 295
+K+ELQQQQQQVVQLEG+ENA AR LLGK IN++LA+MAVLLVFVST+AN + PLMKTR
Sbjct: 617 TKLELQQQQQQVVQLEGVENANARALLGKFINVILALMAVLLVFVSTIANFITPLMKTRL 676
Query: 296 RTFSTLFLVVFIAFLWKHWDALFSYVE 322
R ST LV+ + LWKHWD+L +E
Sbjct: 677 RITSTTLLVLVLFLLWKHWDSLTYLLE 703
>gi|188497714 transmembrane and coiled-coil domain family 3 [Homo
sapiens]
Length = 477
Score = 286 bits (731), Expect = 2e-77
Identities = 161/323 (49%), Positives = 216/323 (66%), Gaps = 13/323 (4%)
Query: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
+H+ LKD K + + ++S K G S + V +K RE A+LIRNKFGSAD
Sbjct: 163 IHRSLKDAHVK-SRTAPHCMESSKSGMPGVSL---TPPVFVFNKSREFANLIRNKFGSAD 218
Query: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
NI +LK+SLEE + + + +A G + + PKYGS+++CSS TSGS +N A GA
Sbjct: 219 NIAHLKNSLEEFRPEASARAYGGSATIVNKPKYGSDDECSSGTSGSADSNGNQSFGAGGA 278
Query: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
S TLD Q +L E++EI++TQA+L E E LK ++R+Y I QTLQEERYR
Sbjct: 279 S-----TLDSQGK-LAVILEELREIKDTQAQLAEDIEALKVQFKREYGFISQTLQEERYR 332
Query: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
ERLE+QL+DLT+LHQ+E NLKQELAS+EEK+AYQ+YER+RDIQEALE+CQTRISK+EL
Sbjct: 333 YERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRDIQEALESCQTRISKLEL 392
Query: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
QQ+QQ +Q + A+ LLG+ IN++LA M V+LV VST+A V P+MK+R T
Sbjct: 393 HQQEQQALQ---TDTVNAKVLLGRCINVILAFMTVILVCVSTIAKFVSPMMKSRCHILGT 449
Query: 301 LFLVVFIAFLWKHWDALFSYVER 323
F V +A K+WD + +ER
Sbjct: 450 FFAVTLLAIFCKNWDHILCAIER 472
>gi|4503177 testis expressed 28 [Homo sapiens]
Length = 410
Score = 122 bits (307), Expect = 3e-28
Identities = 72/179 (40%), Positives = 108/179 (60%), Gaps = 5/179 (2%)
Query: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL 200
E++E + L+ES+ +LKE D L++++LQEE+ R +EEQ+N + NEI
Sbjct: 208 ELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIY 267
Query: 201 NLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATAR- 259
NLK LA EE++AY SYERA++I E E ++RISK+E+ QQV QLE E+ +R
Sbjct: 268 NLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQVTQLEAAEHLQSRP 324
Query: 260 -NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDAL 317
+L K ++ L++ VLLVFVST+ C L+ +R T + L L+ W+ W A+
Sbjct: 325 PQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAI 383
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.4 bits (111), Expect = 2e-05
Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 19/134 (14%)
Query: 137 ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER------------- 183
A E+++ T + EE+ LK I +T +EER ++
Sbjct: 411 AAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 470
Query: 184 ---LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
EEQ+ L +LH+ E+ +QEL +K+ + E ++ ALE Q+ K+
Sbjct: 471 KKSSEEQIAKLQKLHEKELARKEQELT---KKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 241 QQQQQQVVQLEGLE 254
+++QQ+ + LE LE
Sbjct: 528 EKEQQESLALEELE 541
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/171 (23%), Positives = 78/171 (45%), Gaps = 39/171 (22%)
Query: 128 LDMQSSGFDALLHEIQEIRETQARLEESFETLKE------------------HYQRDYSL 169
LD++ + ++L E+ E+ + + +LEE LK+ H+Q+
Sbjct: 679 LDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDS 738
Query: 170 IMQTLQEERYRCER-LEEQLNDLTEL----------HQNEILNLKQELASMEEKIAYQSY 218
I++ + R E+ L++Q+N L L HQ + NL+ ++ E ++ Q
Sbjct: 739 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGEL--QQA 796
Query: 219 ERARDIQEALEAC---QTRISKMELQQQQQQVVQLEGLENATARNLLGKLI 266
D+ ++ ++ QT+ + +L Q QQ+++ LE T R LL K +
Sbjct: 797 SAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLE-----TERILLTKQV 842
Score = 38.5 bits (88), Expect = 0.008
Identities = 49/226 (21%), Positives = 90/226 (39%), Gaps = 20/226 (8%)
Query: 44 KPREIASL---IRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCS 100
K EIA L I+ + + K+ E ++ KAL + + + E
Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDE 439
Query: 101 SATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQ-ARLEESFETL 159
+ + + S K +D+ + + ++Q++ E + AR E+
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK 499
Query: 160 KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYE 219
+ +R++ M+ E+ E L E Q E L L +EL ++ I +S
Sbjct: 500 LQTREREFQEQMKVALEKSQ-----SEYLKISQEKEQQESLAL-EELELQKKAILTESEN 553
Query: 220 RARDIQEALEACQTRISKME------LQQQQQQ----VVQLEGLEN 255
+ RD+Q+ E +TRI ++E LQ+ + Q V LE +N
Sbjct: 554 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKN 599
Score = 37.4 bits (85), Expect = 0.019
Identities = 48/206 (23%), Positives = 84/206 (40%), Gaps = 25/206 (12%)
Query: 66 KDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKT 125
K++L+E Q+D+ + L I + + K A + G +
Sbjct: 316 KEALQE-QLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH 374
Query: 126 NTLDMQSSGFDALLHEIQEI----RETQARLEESFETLKEHYQRDYSLIMQTLQEERYRC 181
TL+M+ L I+++ E + + E+S E ++ S +T + R
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLK 434
Query: 182 ERLEEQLNDLTELHQNEILNLKQELA------------SMEEKIA----YQSYERARDIQ 225
++EQ+ + + + E ++L+QEL+ S EE+IA E AR Q
Sbjct: 435 AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ 494
Query: 226 EALEACQTRISKMELQQQQQQVVQLE 251
E + QTR E + Q+Q V LE
Sbjct: 495 ELTKKLQTR----EREFQEQMKVALE 516
Score = 37.0 bits (84), Expect = 0.024
Identities = 27/125 (21%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 126 NTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLE 185
N L+ + +G + E Q++ + RL++ L++ +Q++ ++ + +ER E+++
Sbjct: 1926 NDLEFKLAGAE---REKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQERE--EKIK 1980
Query: 186 EQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQ 245
++ DL H + LKQ + ++A + E I+E + Q + L+ Q+
Sbjct: 1981 QEQEDLELKHNS---TLKQLMREFNTQLAQKEQELEMTIKETINKAQ-EVEAELLESHQE 2036
Query: 246 QVVQL 250
+ QL
Sbjct: 2037 ETNQL 2041
Score = 35.4 bits (80), Expect = 0.070
Identities = 31/132 (23%), Positives = 65/132 (49%), Gaps = 19/132 (14%)
Query: 128 LDMQSSGFDALLHEIQE-----IRETQARLE----ESFETLKEHYQRDYSLIMQTLQEER 178
L + F+A + E+ + I + +RLE E E+L E ++R+ + ++ ++
Sbjct: 992 LSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEK-- 1049
Query: 179 YRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEAL----EACQTR 234
+L +Q +L E+H+ ++ +QE+A +++KI E+ +E E +
Sbjct: 1050 ----KLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQD 1105
Query: 235 ISKMELQQQQQQ 246
+ ELQ+Q +Q
Sbjct: 1106 TTLNELQEQLKQ 1117
Score = 33.5 bits (75), Expect = 0.27
Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 15/155 (9%)
Query: 116 IAVGASSSKTNTLDMQSSGFDALLHEIQEI-RETQARLEESFETLK---EHYQRDYSLIM 171
+ V SS+ +Q L + QE+ ++ Q R E E +K E Q +Y I
Sbjct: 467 VDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIS 526
Query: 172 QTL-QEERYRCERLEEQLNDLTELHQNEILNLKQE----------LASMEEKIAYQSYER 220
Q Q+E E LE Q + +N++ +L+QE L S EK ++ +
Sbjct: 527 QEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 586
Query: 221 ARDIQEALEACQTRISKMELQQQQQQVVQLEGLEN 255
++D+ LEA + + +K ++ +LE L++
Sbjct: 587 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKH 621
Score = 33.1 bits (74), Expect = 0.35
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 160 KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE--LHQNEILNLK-QELASMEEKI-AY 215
K++ + + + +TLQE+ C+ LE+++ +L + Q E+ ++ +EL S EK+ A
Sbjct: 1828 KQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1887
Query: 216 QSYERARDIQEALEACQTRISKMELQQ 242
Q + E LE SK L Q
Sbjct: 1888 QQMDGRNKPTELLEENTEEKSKSHLVQ 1914
Score = 32.3 bits (72), Expect = 0.60
Identities = 22/119 (18%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 128 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 187
LD Q+ FD L E+++ + + E + ET + + + ++ E L E
Sbjct: 1488 LDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEV 1547
Query: 188 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQ 246
L + + E L Q+L +E + + R ++ +E + + ++ M+ + + ++
Sbjct: 1548 LKNYNQQKDIEHKELVQKLQHFQE-LGEEKDNRVKEAEEKILTLENQVYSMKAELETKK 1605
Score = 30.0 bits (66), Expect = 3.0
Identities = 24/125 (19%), Positives = 57/125 (45%), Gaps = 11/125 (8%)
Query: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL 200
EI+ + + + E+S L E Y+ + + + + E+++++ ++ E + ++L
Sbjct: 923 EIEILTQKLSAKEDSIHILNEEYETKF-------KNQEKKMEKVKQKAKEMQETLKKKLL 975
Query: 201 N----LKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENA 256
+ LK+EL + +++ + + + E +A IS + + Q Q+E L
Sbjct: 976 DQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEV 1035
Query: 257 TARNL 261
R L
Sbjct: 1036 HRREL 1040
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 46.2 bits (108), Expect = 4e-05
Identities = 38/144 (26%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 129 DMQSSGFD----ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERL 184
DM +GF +L E+Q+I +++ E S +K+ RD ++ +EE L
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL-RDLEAKVKDQEEE------L 1558
Query: 185 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQ 244
+EQ + L Q + L L+ E+ M + + + R +++EA ++CQ ++ +ME+Q ++
Sbjct: 1559 DEQAGTIQMLEQAK-LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 245 QQVVQLEGLENATARNLLGKLINI 268
+ + + L R L GKL +
Sbjct: 1618 EYEDKQKVLRE--KRELEGKLATL 1639
Score = 37.7 bits (86), Expect = 0.014
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 64 NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSS 123
+LK LEE +D AG V+S S+E A+ V V
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV---KD 1553
Query: 124 KTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER 183
+ LD Q+ IQ + + + RLE E +++ + ++ + ++E R C++
Sbjct: 1554 QEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
Query: 184 --------LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRI 235
LEE+ D ++ E L+ +LA++ +++ + +E + +++ L+ + +
Sbjct: 1607 KLKQMEVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
Query: 236 SKMEL 240
+ +L
Sbjct: 1666 ADAQL 1670
Score = 32.0 bits (71), Expect = 0.78
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 34/143 (23%)
Query: 142 IQEIRETQARLEESFETLKE--------------HYQRDYSLIMQTLQEERYRCERLEEQ 187
++E+ T+ RL++ FE E Q D + LQ+ + +C+RL +
Sbjct: 1379 VREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAE 1438
Query: 188 LNDLTELH------QNEILNLKQ-----ELA-----SMEEKIAYQSYERARD--IQEALE 229
L D T+LH +N L KQ EL+ + EK+ + +R +D + EA
Sbjct: 1439 LQD-TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 230 ACQTRISK-MELQQQQQQVVQLE 251
Q K M++ Q+VV LE
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLE 1520
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 46.2 bits (108), Expect = 4e-05
Identities = 38/144 (26%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 129 DMQSSGFD----ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERL 184
DM +GF +L E+Q+I +++ E S +K+ RD ++ +EE L
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL-RDLEAKVKDQEEE------L 1558
Query: 185 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQ 244
+EQ + L Q + L L+ E+ M + + + R +++EA ++CQ ++ +ME+Q ++
Sbjct: 1559 DEQAGTIQMLEQAK-LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 245 QQVVQLEGLENATARNLLGKLINI 268
+ + + L R L GKL +
Sbjct: 1618 EYEDKQKVLRE--KRELEGKLATL 1639
Score = 37.7 bits (86), Expect = 0.014
Identities = 38/185 (20%), Positives = 80/185 (43%), Gaps = 19/185 (10%)
Query: 64 NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSS 123
+LK LEE +D AG V+S S+E A+ V V
Sbjct: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV---KD 1553
Query: 124 KTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER 183
+ LD Q+ IQ + + + RLE E +++ + ++ + ++E R C++
Sbjct: 1554 QEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
Query: 184 --------LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRI 235
LEE+ D ++ E L+ +LA++ +++ + +E + +++ L+ + +
Sbjct: 1607 KLKQMEVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
Query: 236 SKMEL 240
+ +L
Sbjct: 1666 ADAQL 1670
Score = 32.0 bits (71), Expect = 0.78
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 34/143 (23%)
Query: 142 IQEIRETQARLEESFETLKE--------------HYQRDYSLIMQTLQEERYRCERLEEQ 187
++E+ T+ RL++ FE E Q D + LQ+ + +C+RL +
Sbjct: 1379 VREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAE 1438
Query: 188 LNDLTELH------QNEILNLKQ-----ELA-----SMEEKIAYQSYERARD--IQEALE 229
L D T+LH +N L KQ EL+ + EK+ + +R +D + EA
Sbjct: 1439 LQD-TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 230 ACQTRISK-MELQQQQQQVVQLE 251
Q K M++ Q+VV LE
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLE 1520
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 125 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 183
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 184 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 232
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 233 TRISKMELQQQQQQVVQ 249
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 125 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 183
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 184 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 232
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 233 TRISKMELQQQQQQVVQ 249
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 5e-05
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 125 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 183
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 184 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 232
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 233 TRISKMELQQQQQQVVQ 249
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 3/140 (2%)
Query: 109 ANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYS 168
A T G + + +T + ++ ++Q++ + R+E + E Q+
Sbjct: 10 AEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINE-VQQAKK 68
Query: 169 LIMQTLQEERYRCERLEEQLNDL--TELHQNEILNLKQELASMEEKIAYQSYERARDIQE 226
+ L E R CE L+++L+ L ++H EIL+ KQE + + A
Sbjct: 69 KANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHT 128
Query: 227 ALEACQTRISKMELQQQQQQ 246
L+ C+ RIS + LQ ++++
Sbjct: 129 MLQECKERISALNLQIEEEK 148
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 3/140 (2%)
Query: 109 ANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYS 168
A T G + + +T + ++ ++Q++ + R+E + E Q+
Sbjct: 10 AEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINE-VQQAKK 68
Query: 169 LIMQTLQEERYRCERLEEQLNDL--TELHQNEILNLKQELASMEEKIAYQSYERARDIQE 226
+ L E R CE L+++L+ L ++H EIL+ KQE + + A
Sbjct: 69 KANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHT 128
Query: 227 ALEACQTRISKMELQQQQQQ 246
L+ C+ RIS + LQ ++++
Sbjct: 129 MLQECKERISALNLQIEEEK 148
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 7/94 (7%)
Query: 161 EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL-NLKQELASMEEKI--AYQS 217
E Q + + ++ER RC LE ++ +L H+N+ L +L QE ++++++ QS
Sbjct: 246 EQLQEENFRLESGREDERLRCAELEREVAELQ--HRNQALTSLAQEAQALKDEMDELRQS 303
Query: 218 YERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
ERA ++ L +C+ R+ EL++ ++QV QLE
Sbjct: 304 SERAGQLEATLTSCRRRLG--ELRELRRQVRQLE 335
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 7/94 (7%)
Query: 161 EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL-NLKQELASMEEKI--AYQS 217
E Q + + ++ER RC LE ++ +L H+N+ L +L QE ++++++ QS
Sbjct: 246 EQLQEENFRLESGREDERLRCAELEREVAELQ--HRNQALTSLAQEAQALKDEMDELRQS 303
Query: 218 YERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
ERA ++ L +C+ R+ EL++ ++QV QLE
Sbjct: 304 SERAGQLEATLTSCRRRLG--ELRELRRQVRQLE 335
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 43.5 bits (101), Expect = 3e-04
Identities = 42/183 (22%), Positives = 80/183 (43%), Gaps = 12/183 (6%)
Query: 77 AGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFD 136
+G + G S + P+ + A S VGA+ G + L+ Q
Sbjct: 43 SGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQ 102
Query: 137 ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQ 196
HE ++++ Q LE L++ Q+D + LQ+E+++ +E +L +HQ
Sbjct: 103 QPQHE--QLQQPQPHLE-----LQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQ 155
Query: 197 NEILNLKQ-----ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
+ L +Q L +E++ Q + + +Q+ + Q + LQQQQ+Q+ Q +
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQ 215
Query: 252 GLE 254
L+
Sbjct: 216 LLQ 218
Score = 43.5 bits (101), Expect = 3e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 138 LLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQN 197
L+H+ Q+++ Q + ++ + +E Q + Q LQ++ E+L++Q+ + L Q
Sbjct: 152 LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQ----EQLQQQVQEQQLLQQQ 207
Query: 198 EILNLKQELASMEEKIAYQSY----ERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 253
+ +Q+L +E++ Q + E+ + Q+ L Q + +L QQQQ +Q + L
Sbjct: 208 QEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLL 267
Query: 254 ENATAR 259
E A+
Sbjct: 268 EQQQAQ 273
Score = 31.6 bits (70), Expect = 1.0
Identities = 26/120 (21%), Positives = 59/120 (49%), Gaps = 13/120 (10%)
Query: 143 QEIRETQARLEESFETLKEHYQRDYSLIMQTL--QEERYRCERLEEQLNDLTELHQNEIL 200
Q++ + Q +L++ + + Q+ L Q L Q+E+ + ++ ++Q L + Q +L
Sbjct: 185 QQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLL 244
Query: 201 N---------LKQELASMEEKIAYQSYERARD--IQEALEACQTRISKMELQQQQQQVVQ 249
L+Q+ A +++++ Q + + + + E Q + + LQQQQ+Q+ Q
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQ 304
Score = 31.6 bits (70), Expect = 1.0
Identities = 34/134 (25%), Positives = 63/134 (47%), Gaps = 11/134 (8%)
Query: 128 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQT-LQEERYRCERLEE 186
L Q + L E Q+ + Q L + E L++ Q+ Q LQ+++ + LE
Sbjct: 255 LQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEP 314
Query: 187 QLNDLTELHQNEI-LNLKQELASMEEKIA-YQSYERARD-------IQEALEACQTRISK 237
+ + EL + L +QEL +++ Q ER ++ +QE L+ + ++ +
Sbjct: 315 EEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQ 374
Query: 238 MELQQQQQQVVQLE 251
+ Q +QQ+ VQLE
Sbjct: 375 QQQQLEQQE-VQLE 387
Score = 29.6 bits (65), Expect = 3.9
Identities = 24/109 (22%), Positives = 57/109 (52%), Gaps = 12/109 (11%)
Query: 139 LHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 198
L + Q +++ + ++ F+ +E Q+ L++ LQ++ +L++QL + +
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL--LQQQG----QLQQQLLQQQQAQLQQ 264
Query: 199 ILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 247
L L+Q+ A +++++ Q E+ + Q+ Q + + + Q QQQQ+
Sbjct: 265 QL-LEQQQAQLQQQLLLQQQEQLQQQQQ-----QQLLQQQQEQLQQQQL 307
>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
Length = 790
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/241 (24%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 47 EIASLIRNKFGSADNIP---NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSA- 102
E A N G D+I N+K + EE +V+ + ++ + +SS + C A
Sbjct: 131 ECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSS-----LVVDRESS-----HDGCQDAL 180
Query: 103 --------TSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRE------- 147
TS + + + + ++ N L++ L + Q+ R
Sbjct: 181 NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFV 240
Query: 148 TQARLEESFETLKEHYQRDYSLIMQTLQEER-YRCERLEEQLNDLTELHQNEIL--NLKQ 204
TQ + + K Y+ LI L+ ER ++ E+L EQL EL Q ++L + ++
Sbjct: 241 TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300
Query: 205 ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGK 264
EL + EK+ + + +R + E L+A T + Q Q Q EG A++L+ K
Sbjct: 301 ELTQLREKLR-EGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQK 357
Query: 265 L 265
L
Sbjct: 358 L 358
>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
sapiens]
Length = 790
Score = 43.5 bits (101), Expect = 3e-04
Identities = 58/241 (24%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 47 EIASLIRNKFGSADNIP---NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSA- 102
E A N G D+I N+K + EE +V+ + ++ + +SS + C A
Sbjct: 131 ECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSS-----LVVDRESS-----HDGCQDAL 180
Query: 103 --------TSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRE------- 147
TS + + + + ++ N L++ L + Q+ R
Sbjct: 181 NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFV 240
Query: 148 TQARLEESFETLKEHYQRDYSLIMQTLQEER-YRCERLEEQLNDLTELHQNEIL--NLKQ 204
TQ + + K Y+ LI L+ ER ++ E+L EQL EL Q ++L + ++
Sbjct: 241 TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300
Query: 205 ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGK 264
EL + EK+ + + +R + E L+A T + Q Q Q EG A++L+ K
Sbjct: 301 ELTQLREKLR-EGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQK 357
Query: 265 L 265
L
Sbjct: 358 L 358
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 43.1 bits (100), Expect = 3e-04
Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 20/145 (13%)
Query: 120 ASSSKTNTLDMQSSGFDALLH----EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQ 175
A K QSSG H E+QE++ET + E ++L+ + + +TL
Sbjct: 1450 AQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVEN----LQKTLS 1505
Query: 176 EERYRCERLEEQLNDLTELHQNEILNLKQEL---ASMEEKIAYQSYERARDIQEALEACQ 232
E+ L+EQ L Q+E+ L+Q+L + EE++ Q E+ ++A+ A +
Sbjct: 1506 EKETEARNLQEQTVQL----QSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1561
Query: 233 TRIS-----KMELQQQQQQVVQLEG 252
++I+ K +L ++ +++ Q G
Sbjct: 1562 SKIAHLAGVKDQLTKENEELKQRNG 1586
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 12/140 (8%)
Query: 123 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 182
S+T T SS + L HEI +++ +LE E + + +L +Q L +R
Sbjct: 829 SETETKQRLSSQIEKLEHEISHLKK---KLENEVE---QRHTLTRNLDVQLLDTKRQLDT 882
Query: 183 RLEEQLN--DLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEA-LEACQTRISKME 239
LN +L + Q EI LKQ L++ME ++A QS +R Q + E +S +
Sbjct: 883 ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVS--Q 940
Query: 240 LQQQQQQVVQL-EGLENATA 258
L+Q ++QV L E L+ +T+
Sbjct: 941 LRQTEEQVNDLKERLKTSTS 960
Score = 32.7 bits (73), Expect = 0.46
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 20/170 (11%)
Query: 142 IQEIRETQARLEESFETLK---EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 198
++ +E +RLEE LK EH Q+ ++ L+E + + +EE+ ++ H +
Sbjct: 226 LENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAH-IK 284
Query: 199 ILNLKQELASMEE-------KIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
+ NL + A E + + ++ ++ EA +A Q + ++E + Q + LE
Sbjct: 285 LSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLE 344
Query: 252 -------GLENATARNLLGKLINILLA--VMAVLLVFVSTVANCVVPLMK 292
LENA K +L+ +A + + VA V P MK
Sbjct: 345 KIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMK 394
Score = 32.7 bits (73), Expect = 0.46
Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 31/173 (17%)
Query: 120 ASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLK------EHYQRDYSLIMQT 173
AS S T Q S + + + ++R+T+ ++ + E LK E YQ + + ++
Sbjct: 916 ASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEES 975
Query: 174 LQEERYRCE--------RLEEQLNDLTELHQN--EILNLKQELA--------SMEEKIAY 215
L +E+ E RL+E T+L + E+ KQEL SME++++
Sbjct: 976 LNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSE 1035
Query: 216 QSYERA---RDIQEALEACQTRISKMELQQ---QQQQVVQLEGLENATARNLL 262
+ ++QEAL+ T +S + + Q+Q + +E +N R L+
Sbjct: 1036 LKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEA-QNKYERELM 1087
Score = 28.5 bits (62), Expect = 8.6
Identities = 30/122 (24%), Positives = 56/122 (45%), Gaps = 13/122 (10%)
Query: 143 QEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ---LND-LTELHQNE 198
Q + ET + E K ++ ++ + + RCE LE+Q L+D + +L
Sbjct: 1111 QHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKV 1170
Query: 199 ILNLKQEL-------ASMEEKIAYQSYERARDIQEALEACQTR--ISKMELQQQQQQVVQ 249
+ ++K+ + S E K Q E R I+ E +TR ++++E + +Q+V
Sbjct: 1171 VASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVEL 1230
Query: 250 LE 251
LE
Sbjct: 1231 LE 1232
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 42.7 bits (99), Expect = 4e-04
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 14/129 (10%)
Query: 129 DMQSSGFDALLHEIQE--IRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR--CERL 184
+++++ +LL+ QE +RE + RL E E L+E +R QEER R ERL
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEER------LCEQEERLREQEERL 236
Query: 185 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKME--LQQ 242
EQ L E + + ++ L EE++ Q ER R+ +E L + R+ + E L++
Sbjct: 237 REQEERLCE-QEERLREHEERLCEQEERLCEQE-ERLREQEERLHEQEERLCEQEERLRE 294
Query: 243 QQQQVVQLE 251
Q++++ + E
Sbjct: 295 QEERLCEQE 303
Score = 39.7 bits (91), Expect = 0.004
Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 10/121 (8%)
Query: 136 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE-L 194
+ L + + +RE + RL E E L E +R + ++E CE+ EE+L + E L
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQ-EERLREQEERL 278
Query: 195 HQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKME--LQQQQQQVVQLEG 252
H+ E + L EE++ Q ER + +E L + R+ + E L++Q++++ + E
Sbjct: 279 HEQE-----ERLCEQEERLREQE-ERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332
Query: 253 L 253
L
Sbjct: 333 L 333
Score = 37.0 bits (84), Expect = 0.024
Identities = 34/139 (24%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 136 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE-L 194
+ L + + + E + RL E E L+E +R + ++E CE+ EE+L + E L
Sbjct: 269 ERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EERLREQEERL 327
Query: 195 HQNEILNLKQELASMEEKIAYQ-----SYERARDIQEALEACQTRISKMELQQQQQQVVQ 249
+ E L ++ L EK+ Q ER + + LE + + + L+QQ +++ Q
Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQ 387
Query: 250 LEGLENATARNLLGKLINI 268
E L+ L +++ +
Sbjct: 388 QETLQELERLRELERMLEL 406
Score = 33.5 bits (75), Expect = 0.27
Identities = 26/118 (22%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 136 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELH 195
+ L + + + E + RL E E L E +R + ++E CE+ EE+L +
Sbjct: 255 ERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQ-EERLRE----Q 309
Query: 196 QNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 253
+ + ++ L EE++ Q E+ + LE + + + Q++Q+++++ E L
Sbjct: 310 EERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKLLEQERRQEEQERLLERERL 365
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 13/134 (9%)
Query: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE--LHQNE 198
+I+E+ E EE ++E Q + + +QE+ + +R EE++ + E Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEE----EKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 199 ILNLKQELASMEEKIAYQS---YERARDIQEALEACQTRISKMELQQ----QQQQVVQLE 251
+L ++++ EEK+ Q +E+ +QE E Q + KM Q+ QQ++ +Q +
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 252 GLENATARNLLGKL 265
+ LGKL
Sbjct: 551 EVRLQELEERLGKL 564
Score = 38.1 bits (87), Expect = 0.011
Identities = 24/119 (20%), Positives = 64/119 (53%), Gaps = 11/119 (9%)
Query: 136 DALLHEIQEIRETQARLEESFETL--KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE 193
D + + ++IRE + ++ E E + +E R+ +Q +EE +R EE++ + E
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR---QEEKIREQEE 402
Query: 194 LHQNEILNLKQELASMEEKIA------YQSYERARDIQEALEACQTRISKMELQQQQQQ 246
Q ++ ++++ +EKI ++ E+ R+++E ++ + ++ ++E + Q+++
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 30.8 bits (68), Expect = 1.7
Identities = 20/109 (18%), Positives = 56/109 (51%), Gaps = 1/109 (0%)
Query: 143 QEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNL 202
++IRE + + +E +E R+ ++ +EE +R E +L ++ + + ++ +
Sbjct: 395 EKIREQEEKRQEKMWR-QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453
Query: 203 KQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
++++ EEK+ Q + R ++ E + + +L +Q++++ + E
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/134 (25%), Positives = 65/134 (48%), Gaps = 13/134 (9%)
Query: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE--LHQNE 198
+I+E+ E EE ++E Q + + +QE+ + +R EE++ + E Q +
Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEE----EKMQEQEEKIQRQEEKIQEQEEKTWRQEK 490
Query: 199 ILNLKQELASMEEKIAYQS---YERARDIQEALEACQTRISKMELQQ----QQQQVVQLE 251
+L ++++ EEK+ Q +E+ +QE E Q + KM Q+ QQ++ +Q +
Sbjct: 491 LLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQ 550
Query: 252 GLENATARNLLGKL 265
+ LGKL
Sbjct: 551 EVRLQELEERLGKL 564
Score = 38.1 bits (87), Expect = 0.011
Identities = 24/119 (20%), Positives = 64/119 (53%), Gaps = 11/119 (9%)
Query: 136 DALLHEIQEIRETQARLEESFETL--KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE 193
D + + ++IRE + ++ E E + +E R+ +Q +EE +R EE++ + E
Sbjct: 346 DKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWR---QEEKIREQEE 402
Query: 194 LHQNEILNLKQELASMEEKIA------YQSYERARDIQEALEACQTRISKMELQQQQQQ 246
Q ++ ++++ +EKI ++ E+ R+++E ++ + ++ ++E + Q+++
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 30.8 bits (68), Expect = 1.7
Identities = 20/109 (18%), Positives = 56/109 (51%), Gaps = 1/109 (0%)
Query: 143 QEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNL 202
++IRE + + +E +E R+ ++ +EE +R E +L ++ + + ++ +
Sbjct: 395 EKIREQEEKRQEKMWR-QEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453
Query: 203 KQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 251
++++ EEK+ Q + R ++ E + + +L +Q++++ + E
Sbjct: 454 EEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQE 502
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 41.6 bits (96), Expect = 0.001
Identities = 35/124 (28%), Positives = 64/124 (51%), Gaps = 11/124 (8%)
Query: 141 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRC-ERLEEQLNDLTELHQNEI 199
E+++I + + + E + L+ H+Q + + LQ E RC E LE + + + Q E+
Sbjct: 390 ELEKIFQDKNQAERALRNLESHHQAAIEKLREDLQSEHGRCLEDLEFKFKESEKEKQLEL 449
Query: 200 LNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVV----QLEGLEN 255
NL+ AS E+ + QS E R + L++ +T S+ EL + +Q++ ++E LE
Sbjct: 450 ENLQ---ASYED-LKAQSQEEIRRLWSQLDSART--SRQELSELHEQLLARTSRVEDLEQ 503
Query: 256 ATAR 259
R
Sbjct: 504 LKQR 507
Score = 35.0 bits (79), Expect = 0.092
Identities = 40/142 (28%), Positives = 59/142 (41%), Gaps = 30/142 (21%)
Query: 140 HEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEI 199
H++Q + Q L+E E LK + Y LQ E + LE+ ++L E HQ E+
Sbjct: 677 HKVQ-LSLLQTELKEEIELLKIENRNLYG----KLQHETRLKDDLEKVKHNLIEDHQKEL 731
Query: 200 LNLKQELASMEEKI-------AYQSYERARDIQEALEAC------------QTRISKMEL 240
N KQ+ M+++ E R+ +E L QT I+K EL
Sbjct: 732 NNAKQKTELMKQEFQRKETDWKVMKEELQREAEEKLTLMLLELREKAESEKQTIINKFEL 791
Query: 241 ------QQQQQQVVQLEGLENA 256
Q Q QQ Q+ LE +
Sbjct: 792 REAEMRQLQDQQAAQILDLERS 813
Score = 30.8 bits (68), Expect = 1.7
Identities = 27/122 (22%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
Query: 139 LHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER-LEEQLNDLTELHQN 197
L E++ ETQ +H Q + + L+ E RCE L ++ + L+EL Q
Sbjct: 2687 LEELRASLETQRAQSSRLCVALKHEQTAKDNLQKELRIEHSRCEALLAQERSQLSEL-QK 2745
Query: 198 EILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISK------MELQQQQQQVVQLE 251
++ K + E + ++ + Q EAC + ++ +L++++ +VV L+
Sbjct: 2746 DLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQDTQAHHALLQKLKEEKSRVVDLQ 2805
Query: 252 GL 253
+
Sbjct: 2806 AM 2807
Score = 30.4 bits (67), Expect = 2.3
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 21/121 (17%)
Query: 139 LHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 198
L E QE + +L + +T+ + D L E R + E+L L ++ Q E
Sbjct: 2585 LSEEQEKANSVQKLLAAEQTVVRDLKSD-------LCESRQKSEQLSRSLCEV----QQE 2633
Query: 199 ILNLKQELASMEE--KIAYQSYE----RARDIQEALEACQTRISKMELQQQQQQVVQLEG 252
+L L+ L+S E K A Q E + R +Q LE Q R LQ++ Q LE
Sbjct: 2634 VLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQLR----HLQRESQSAKALEE 2689
Query: 253 L 253
L
Sbjct: 2690 L 2690
Score = 30.0 bits (66), Expect = 3.0
Identities = 43/198 (21%), Positives = 83/198 (41%), Gaps = 23/198 (11%)
Query: 69 LEEGQVDDAGKALGVISNFQSSPKYGSEEDC---SSATSGSVGANSTTGGIAVGASSSKT 125
LE G+ D+AG QS +G E + S + + T + ++ T
Sbjct: 226 LESGREDEAGL-------HQSQAVHGLELEALRLSLSNMHTAQLELTQANLQKEKETALT 278
Query: 126 NTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLE 185
+M +S QE+ Q+R + E L+E + R+ ++ +E L+
Sbjct: 279 ELREMLNS------RRAQELALLQSRQQHELELLREQHAREKEEVVLRCGQE---AAELK 329
Query: 186 EQLNDLTELHQNEILNLKQELASMEEKIAYQSY--ERARDIQEALEACQTRISKMELQQQ 243
E+L E + + LK++ S E+ + ++ E + Q +E Q + K EL +Q
Sbjct: 330 EKLQSEMEKNAQIVKTLKEDWES-EKDLCLENLRKELSAKHQSEMEDLQNQFQK-ELAEQ 387
Query: 244 QQQVVQLEGLENATARNL 261
+ ++ ++ +N R L
Sbjct: 388 RAELEKIFQDKNQAERAL 405
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/80 (38%), Positives = 51/80 (63%), Gaps = 12/80 (15%)
Query: 170 IMQTLQEERY----RCERLEEQLNDLTELHQNEILNLKQELASMEE-----KIAYQ-SYE 219
+ Q L+EER + + LEEQL + T LH+ EI NLKQ+L +EE ++ YQ S E
Sbjct: 272 LTQQLEEERIQHQQKVKELEEQLENET-LHK-EIHNLKQQLELLEEDKKELELKYQNSEE 329
Query: 220 RARDIQEALEACQTRISKME 239
+AR+++ +++ Q R+++ E
Sbjct: 330 KARNLKHSVDELQKRVNQSE 349
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/80 (38%), Positives = 51/80 (63%), Gaps = 12/80 (15%)
Query: 170 IMQTLQEERY----RCERLEEQLNDLTELHQNEILNLKQELASMEE-----KIAYQ-SYE 219
+ Q L+EER + + LEEQL + T LH+ EI NLKQ+L +EE ++ YQ S E
Sbjct: 272 LTQQLEEERIQHQQKVKELEEQLENET-LHK-EIHNLKQQLELLEEDKKELELKYQNSEE 329
Query: 220 RARDIQEALEACQTRISKME 239
+AR+++ +++ Q R+++ E
Sbjct: 330 KARNLKHSVDELQKRVNQSE 349
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/161 (27%), Positives = 76/161 (47%), Gaps = 27/161 (16%)
Query: 118 VGASSSKTNTLDMQSSGFDALLHEI-QEIRETQARLEESFETLKEHYQRDYSLIMQTLQE 176
V S++ LD + FD +L E Q+ ETQA LE S Q++ ++L
Sbjct: 1435 VERSNAACAALDKKQRNFDKVLSEWKQKYEETQAELEAS--------QKE----SRSLST 1482
Query: 177 ERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRIS 236
E ++ + + E+ D E + E NL+QE++ + E+IA E + I E +
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA----EGGKQIHE--------LE 1530
Query: 237 KMELQQQQQQVVQLEGLENATA--RNLLGKLINILLAVMAV 275
K++ Q +Q++ LE A A + GK++ I L + V
Sbjct: 1531 KIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQV 1571
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 41.2 bits (95), Expect = 0.001
Identities = 30/133 (22%), Positives = 66/133 (49%), Gaps = 13/133 (9%)
Query: 128 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLI-------MQTLQEERYR 180
L+ + +D + QE+ E ++L++ E L+E Y R L+ + +++ +
Sbjct: 452 LENEKRKYDEHVKSNQELSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVK 511
Query: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
++++ +L + EL I + E+ ++ KI E+ + IQ+ + A Q +E
Sbjct: 512 LQKVKYRLTNEVELRDKRINQFEDEIGILQHKI-----EKEKAIQDQITA-QNDTLLLEK 565
Query: 241 QQQQQQVVQLEGL 253
++ Q+QV++ E L
Sbjct: 566 RKLQEQVIEQEQL 578
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 41.2 bits (95), Expect = 0.001
Identities = 47/207 (22%), Positives = 82/207 (39%), Gaps = 31/207 (14%)
Query: 39 GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEED 98
G V S + S+ ++ ADN+PNL D + F S+ S
Sbjct: 88 GGVPSPGASLTSMAASQNHDADNVPNLMDETK---------------TFSSTE---SLRQ 129
Query: 99 CSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFET 158
S +G V ++T ASS+ L+ S + L + T +L + E
Sbjct: 130 LSQQLNGLVCESATCVNGEGPASSANLKDLE---SRYQQLAVALDSSYVTNKQLNITIEK 186
Query: 159 LKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAY--- 215
LK+ Q I L+EE+ C + + L + ++H I L E A ++ +A+
Sbjct: 187 LKQQNQE----ITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAELQTALAHTQH 242
Query: 216 ---QSYERARDIQEALEACQTRISKME 239
Q + D+ L+ + R+ ++E
Sbjct: 243 AARQKEGESEDLASRLQYSRRRVGELE 269
Score = 33.5 bits (75), Expect = 0.27
Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Query: 144 EIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILN-- 201
E + +RL+ S + E + ++ Q + +RY E +E+ EL++N N
Sbjct: 250 ESEDLASRLQYSRRRVGELERALSAVSTQQKKADRYNKELTKERDALRLELYKNTQSNED 309
Query: 202 LKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQ 244
LKQE + +EEK+ E+A +Q LE Q ++ EL QQ
Sbjct: 310 LKQEKSELEEKLRVLVTEKA-GMQLNLEELQKKLEMTELLLQQ 351
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/111 (25%), Positives = 55/111 (49%), Gaps = 3/111 (2%)
Query: 138 LLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDL--TELH 195
++ ++Q++ + R+E + E Q+ + L E R CE L+++L+ L ++H
Sbjct: 3 MVQKLQKVGSLEPRVEVLINRINE-VQQAKKKANKDLGEARTICEALQKELDSLHGEKVH 61
Query: 196 QNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQ 246
EIL+ KQE + + A L+ C+ RIS + LQ ++++
Sbjct: 62 LKEILSKKQETLRILRLHCQEKESEAHRKHTMLQECKERISALNLQIEEEK 112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,496,512
Number of Sequences: 37866
Number of extensions: 430959
Number of successful extensions: 4828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 513
Number of HSP's that attempted gapping in prelim test: 3436
Number of HSP's gapped (non-prelim): 1642
length of query: 329
length of database: 18,247,518
effective HSP length: 103
effective length of query: 226
effective length of database: 14,347,320
effective search space: 3242494320
effective search space used: 3242494320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.