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Search of human proteins with 38788193
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
(378 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 755 0.0
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens] 382 e-106
gi|134244587 endothelial differentiation, sphingolipid G-protein... 297 9e-81
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 296 2e-80
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 249 3e-66
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 224 1e-58
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 224 1e-58
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 205 6e-53
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens] 195 6e-50
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 128 7e-30
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 128 7e-30
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 128 7e-30
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 128 7e-30
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 128 7e-30
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 128 7e-30
gi|4885295 G protein-coupled receptor 12 [Homo sapiens] 118 1e-26
gi|5174535 melanocortin 5 receptor [Homo sapiens] 115 6e-26
gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 114 2e-25
gi|119508433 melanocortin 4 receptor [Homo sapiens] 108 1e-23
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 107 2e-23
gi|170671732 melanocortin 3 receptor [Homo sapiens] 105 7e-23
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens] 102 4e-22
gi|4505127 melanocortin 2 receptor [Homo sapiens] 99 8e-21
gi|5921992 adenosine A2a receptor [Homo sapiens] 96 4e-20
gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] 93 4e-19
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 85 1e-16
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 85 1e-16
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 85 1e-16
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 85 1e-16
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 85 1e-16
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 755 bits (1950), Expect = 0.0
Identities = 378/378 (100%), Positives = 378/378 (100%)
Query: 1 MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV 60
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV
Sbjct: 1 MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMV 60
Query: 61 LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV 120
LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV
Sbjct: 61 LIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFV 120
Query: 121 ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH 180
ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH
Sbjct: 121 ALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLH 180
Query: 181 NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA 240
NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA
Sbjct: 181 NLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMA 240
Query: 241 LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL 300
LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL
Sbjct: 241 LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTL 300
Query: 301 ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP 360
ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP
Sbjct: 301 ASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAP 360
Query: 361 SSCIMDKNAALQNGIFCN 378
SSCIMDKNAALQNGIFCN
Sbjct: 361 SSCIMDKNAALQNGIFCN 378
>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
Length = 382
Score = 382 bits (981), Expect = e-106
Identities = 197/353 (55%), Positives = 254/353 (71%), Gaps = 16/353 (4%)
Query: 21 HYQYVGKLAGRLKEASEGST-LTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIG 79
HY Y GKL + E S LT+V+F++IC FI+LEN+ VL+ IWK KFH MY+FIG
Sbjct: 28 HYNYTGKL--NISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIG 85
Query: 80 NLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLT 139
NLAL DLLAG+AY N+L+SG T+ L+P WFLREGSMFVAL AS SLLAIAIER++T
Sbjct: 86 NLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYIT 145
Query: 140 MIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF 199
M+KM+ ++ + R+FLLI CW+I+ LG LPI+GWNC+ L CST+LPLY K YI F
Sbjct: 146 MLKMKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILF 205
Query: 200 CISIFTAILVTIVILYARIYFLVKSSSRKVANHNN-------SERSMALLRTVVIVVSVF 252
C ++FT +L++IVILY RIY LV++ SR++ N SE+S+ALL+TV+IV+SVF
Sbjct: 206 CTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVF 265
Query: 253 IACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRL 312
IACW+PLFIL L+DV C+V+ C ILF+A++F+VLAVLNS NP+IYTL +KEMRRAF R+
Sbjct: 266 IACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRI 325
Query: 313 V--CNC-LVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSS 362
+ C C G PI ++ SRSK S+NSSH K + D P T SS
Sbjct: 326 MSCCKCPSGDSAGKFKRPIIAGMEFSRSK---SDNSSHPQKDEGDNPETIMSS 375
>gi|134244587 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 5 [Homo sapiens]
Length = 353
Score = 297 bits (761), Expect = 9e-81
Identities = 160/336 (47%), Positives = 219/336 (65%), Gaps = 12/336 (3%)
Query: 18 LREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFF 77
++EHY Y + + S + + +++C IV+ENL+VLIA+ +N+KFH+ MY F
Sbjct: 14 VQEHYNYTKETLETQETTSR--QVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLF 71
Query: 78 IGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERH 137
+GNLA DLLAG+A+ N L+SG T L+P WF REGS F+ L AS SLLAIAIERH
Sbjct: 72 LGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERH 131
Query: 138 LTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYI 197
+ + K++ Y ++K R+ LLIG WLI+ LG LPILGWNCL +L CST+LPLY+K Y+
Sbjct: 132 VAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYV 191
Query: 198 AFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWS 257
++IF+ IL+ IV LY RIY +V+SS +A + +++ALL+TV IV+ VFI CW
Sbjct: 192 LCVVTIFSIILLAIVALYVRIYCVVRSSHADMA----APQTLALLKTVTIVLGVFIVCWL 247
Query: 258 PLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFR-LVC-- 314
P F + L+D AC V +CPIL+KA +F ++ LNS +NPVIYT S+++RR R L C
Sbjct: 248 PAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWR 307
Query: 315 -NCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSP 349
V+GR +P L P RS SSS H P
Sbjct: 308 PGVGVQGRRRGGTPGHHLL-PLRS-SSSLERGMHMP 341
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 296 bits (758), Expect = 2e-80
Identities = 155/345 (44%), Positives = 209/345 (60%), Gaps = 21/345 (6%)
Query: 9 LQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNN 68
L+P +E + HY Y GKL G + G V+ L +C+FIVLENL VL+ + ++
Sbjct: 6 LRPAPVSEVIVLHYNYTGKLRGARYQPGAGLRADAVVCLAVCAFIVLENLAVLLVLGRHP 65
Query: 69 KFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCS 128
+FH M+ +G+L L DLLAG AY NIL+SG T LSP +WF REG +FVAL AS S
Sbjct: 66 RFHAPMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLS 125
Query: 129 LLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTI 188
LLAIA+ER LTM + P + R R + W ++ LG LP LGWNCL L CST+
Sbjct: 126 LLAIALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTV 185
Query: 189 LPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKV-----------ANHNNSER 237
LPLY+K Y+ FC+ F IL I LYARIY V++++R++ R
Sbjct: 186 LPLYAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPR 245
Query: 238 SMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVI 297
S+ALLRT+ +V+ F+ACW PLF+L L+DVAC + CP+L +A F+ LA+ NS +NP+I
Sbjct: 246 SLALLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPII 305
Query: 298 YTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSS 342
YTL ++++R A RLVC C G DPS S+ S+S
Sbjct: 306 YTLTNRDLRHALLRLVC-CGRHSCGR---------DPSGSQQSAS 340
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 249 bits (636), Expect = 3e-66
Identities = 141/333 (42%), Positives = 196/333 (58%), Gaps = 5/333 (1%)
Query: 21 HYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGN 80
HY + G+LAGR G L + +VLENL+VL AI + + +Y+ + N
Sbjct: 28 HYNHSGRLAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRRWVYYCLVN 87
Query: 81 LALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTM 140
+ L DLL G AY N+L+SG +TF L+P WFLREG +F AL AST SLL A ER TM
Sbjct: 88 ITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATM 147
Query: 141 IK-MRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF 199
++ + A K RV+ IG+CWL+A LG LP+LGWNCL CS++LPLYSK+YI F
Sbjct: 148 VRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILF 207
Query: 200 CISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPL 259
C+ IF +L TI+ LY I+ LV++S +K ++ LL+TV++++ F+ CW PL
Sbjct: 208 CLVIFAGVLATIMGLYGAIFRLVQASGQKAPRPAARRKARRLLKTVLMILLAFLVCWGPL 267
Query: 260 FILFLIDV-ACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFR-LVCNCL 317
F L L DV + A L W + LAVLNSA+NP+IY+ S+E+ RA L C CL
Sbjct: 268 FGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREVCRAVLSFLCCGCL 327
Query: 318 VRGRGARASPIQPALDPSRSKSSSSNNSSHSPK 350
G + A++ +S+ +SS P+
Sbjct: 328 RLGMRGPGDCLARAVE--AHSGASTTDSSLRPR 358
>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 224 bits (571), Expect = 1e-58
Identities = 116/305 (38%), Positives = 183/305 (60%), Gaps = 9/305 (2%)
Query: 15 NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM 74
NE++ Y GK E + S L L + +C FI+L NL+V++AI+ N +FH +
Sbjct: 27 NESIAFFYNRSGKHLAT--EWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPI 84
Query: 75 YFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAI 134
Y+ + NLA D AG+AY + +G T L+ + W LR+G + +L AS +LLAIAI
Sbjct: 85 YYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAI 144
Query: 135 ERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSK 194
ERH+T+ +M+ + RV ++I + W +A +GA+P +GWNC+ ++ +CS + PLYS
Sbjct: 145 ERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSD 204
Query: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHN-----NSERSMALLRTVVIVV 249
Y+ F V +V+LYA I+ V+ + +++ H+ N + M+LL+TVVIV+
Sbjct: 205 SYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVL 264
Query: 250 SVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAF 309
FI CW+P +L L+DV C C +L ++F++LA NSAMNP+IY+ KEM F
Sbjct: 265 GAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATF 322
Query: 310 FRLVC 314
+++C
Sbjct: 323 RQILC 327
>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 224 bits (571), Expect = 1e-58
Identities = 116/305 (38%), Positives = 183/305 (60%), Gaps = 9/305 (2%)
Query: 15 NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM 74
NE++ Y GK E + S L L + +C FI+L NL+V++AI+ N +FH +
Sbjct: 27 NESIAFFYNRSGKHLAT--EWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHFPI 84
Query: 75 YFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAI 134
Y+ + NLA D AG+AY + +G T L+ + W LR+G + +L AS +LLAIAI
Sbjct: 85 YYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAI 144
Query: 135 ERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSK 194
ERH+T+ +M+ + RV ++I + W +A +GA+P +GWNC+ ++ +CS + PLYS
Sbjct: 145 ERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSD 204
Query: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHN-----NSERSMALLRTVVIVV 249
Y+ F V +V+LYA I+ V+ + +++ H+ N + M+LL+TVVIV+
Sbjct: 205 SYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVIVL 264
Query: 250 SVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAF 309
FI CW+P +L L+DV C C +L ++F++LA NSAMNP+IY+ KEM F
Sbjct: 265 GAFIICWTPGLVLLLLDVCC--PQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSATF 322
Query: 310 FRLVC 314
+++C
Sbjct: 323 RQILC 327
>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
Length = 353
Score = 205 bits (521), Expect = 6e-53
Identities = 115/313 (36%), Positives = 183/313 (58%), Gaps = 13/313 (4%)
Query: 38 GSTLTTVLFL--VICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVN 95
G+ L VL + C FI N +V+ A+ KN KFH Y+ + NLA D AGIAY
Sbjct: 27 GTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFL 86
Query: 96 ILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVF 155
+ +G + +L+ WFLR+G + +L AS +LL IA+ERH+++++MR + + RV
Sbjct: 87 MFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVT 146
Query: 156 LLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAF-CISIFTAILVTIVIL 214
LLI + W IA +GA+P LGWNCL N+ CS++ P+YS+ Y+ F +S A L+ +V++
Sbjct: 147 LLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLI-MVVV 205
Query: 215 YARIYFLVKSSSRKVANHNNSERS-----MALLRTVVIVVSVFIACWSPLFILFLID-VA 268
Y RIY VK + ++ H + S M L++TV+ V+ F+ CW+P ++ L+D +
Sbjct: 206 YLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLN 265
Query: 269 CRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPI 328
CR C + +WF++LA+LNS +NP+IY+ ++M +++C C + R
Sbjct: 266 CR--QCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMIC-CFSQENPERRPSR 322
Query: 329 QPALDPSRSKSSS 341
P+ SRS + S
Sbjct: 323 IPSTVLSRSDTGS 335
>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
Length = 351
Score = 195 bits (495), Expect = 6e-50
Identities = 109/311 (35%), Positives = 176/311 (56%), Gaps = 10/311 (3%)
Query: 15 NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM 74
NET+ Y GK + + L L + ++L NL+V+ AI N +FH +
Sbjct: 10 NETIGFFYNNSGKELSSHWRPKD--VVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPI 67
Query: 75 YFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAI 134
Y+ +GNLA DL AG+AY + +G +T LS WFLR+G + +L AS +LLAIA+
Sbjct: 68 YYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAV 127
Query: 135 ERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSK 194
ERH +++ ++ + R RV +LI W+ A LG LP W+CL L CS + PL S+
Sbjct: 128 ERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSR 187
Query: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANH-----NNSERSMALLRTVVIVV 249
Y+A + + +V +Y RI+F V+ +++A H E +++L++TVVI++
Sbjct: 188 SYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIIL 247
Query: 250 SVFIACWSPLFILFLID-VACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRA 308
F+ CW+P ++ L+D + C ++C +L ++F++LA NS +N +Y+ EMRR
Sbjct: 248 GAFVVCWTPGQVVLLLDGLGC--ESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRT 305
Query: 309 FFRLVCNCLVR 319
F RL+C +R
Sbjct: 306 FRRLLCCACLR 316
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 128 bits (322), Expect = 7e-30
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 88 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
Query: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
Query: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 265
Query: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 266 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 325
Query: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 326 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 382
Query: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
A P+ ++ S +NN++ H A SCI
Sbjct: 383 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 417
>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
Length = 334
Score = 118 bits (295), Expect = 1e-26
Identities = 83/289 (28%), Positives = 141/289 (48%), Gaps = 19/289 (6%)
Query: 47 LVICS---FIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKT 103
+V+C+ I EN +V++ I+ N M+ IG+LAL DLLAGI N + +
Sbjct: 49 IVLCTSGTLISCENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNFVFA---Y 105
Query: 104 FSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHR-VFLLIGMCW 162
S + G + + AS CSLLAI ++R+L++ Y + + ++++ M W
Sbjct: 106 LLQSEATKLVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTVTFTYVMLVMLW 165
Query: 163 LIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLV 222
+ LG LP++GWNCL + CS + PL +K A F + ++ LY +I +V
Sbjct: 166 GTSICLGLLPVMGWNCLRDESTCSVVRPL-TKNNAAILSVSFLFMFALMLQLYIQICKIV 224
Query: 223 KSSSRKVA-NHNNSERSMAL-----LRTVVIVVSVFIACWSPLFILFLIDVACRVQACPI 276
+ ++A H+ S + + T+ I++ F ACW P + LI P
Sbjct: 225 MRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLI----ADYTYPS 280
Query: 277 LFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARA 325
++ ++ A NS +NPVIY ++E+++A + C C+ RA
Sbjct: 281 IY-TYATLLPATYNSIINPVIYAFRNQEIQKALCLICCGCIPSSLAQRA 328
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 115 bits (288), Expect = 6e-26
Identities = 82/297 (27%), Positives = 148/297 (49%), Gaps = 38/297 (12%)
Query: 37 EGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIA---YK 93
E + +FL + +LEN++V+ AI KN H+ MYFF+ +LA+ D+L ++
Sbjct: 34 EDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWET 93
Query: 94 VNILMSGKKTFSLSPTVWFLR------EGSMFVALGASTCSLLAIAIERHLTMI-KMRPY 146
+ I + K ++ F+R + + +++ AS CSLLAIA++R++T+ +R +
Sbjct: 94 ITIYLLNNKHLVIADA--FVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYH 151
Query: 147 DANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKK-YIAFC-ISIF 204
R +I W AF G C + LYS+ Y+ C IS+F
Sbjct: 152 HIMTARRSGAIIAGIW--AFCTG---------------CGIVFILYSESTYVILCLISMF 194
Query: 205 TAILVTIVILYARIYFLVKSSSRKV-----ANHNNSERSMALLRTVVIVVSVFIACWSPL 259
A+L +V LY ++ L ++ +++ A+ SM TV +++ VF CW+P
Sbjct: 195 FAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPF 254
Query: 260 FILFLIDVAC--RVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVC 314
F+ + ++C + + +++L + NS M+P+IY S+EMR+ F ++C
Sbjct: 255 FLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIIC 311
>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
Length = 362
Score = 114 bits (284), Expect = 2e-25
Identities = 84/284 (29%), Positives = 137/284 (48%), Gaps = 24/284 (8%)
Query: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKT 103
VL V + I EN +V+ I M+ +G+LA DLLAG ++ + +
Sbjct: 77 VLLCVSGTVIAGENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHFVF---QY 133
Query: 104 FSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHR-VFLLIGMCW 162
S TV L G + + AS SLLAI ++R+L++ Y + + V LL+ W
Sbjct: 134 LVPSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAATW 193
Query: 163 LIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLV 222
++ LG LP+LGWNCL CS + PL ++ ++A + F + ++ LY RI +V
Sbjct: 194 TVSLGLGLLPVLGWNCLAERAACSVVRPL-ARSHVALLSAAFFMVFGIMLHLYVRICQVV 252
Query: 223 KSSSRKVA--NHNNSERSMALLR----TVVIVVSVFIACWSPLFILFLI----DVACRVQ 272
+ ++A H + +A R T+ +V+ F A W P I ++ D A
Sbjct: 253 WRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVGSHEDPAVYTY 312
Query: 273 ACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC 316
A ++ A NS +NP+IY ++E++RA + L+C C
Sbjct: 313 AT---------LLPATYNSMINPIIYAFRNQEIQRALWLLLCGC 347
>gi|119508433 melanocortin 4 receptor [Homo sapiens]
Length = 332
Score = 108 bits (269), Expect = 1e-23
Identities = 76/284 (26%), Positives = 148/284 (52%), Gaps = 29/284 (10%)
Query: 45 LFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYK----VNILMSG 100
+F+ + +LEN++V++AI KN H+ MYFFI +LA+ D+L ++ V L++
Sbjct: 50 VFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNS 109
Query: 101 KKTFSLSPTVWF--LREGSMFVALGASTCSLLAIAIERHLTMI-KMRPYDANKRHRVFLL 157
T + S TV + + + +L AS CSLL+IA++R+ T+ ++ ++ RV ++
Sbjct: 110 TDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGII 169
Query: 158 IGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYAR 217
I W G L I+ D S + I I++F +L + LY
Sbjct: 170 ISCIWAACTVSGILFII-------YSDSSAV--------IICLITMFFTMLALMASLYVH 214
Query: 218 IYFLVKSSSRKVA--NHNNSERSMALLR---TVVIVVSVFIACWSPLFILFLIDVACRVQ 272
++ + + +++A + R A ++ T+ I++ VF+ CW+P F+ + ++C
Sbjct: 215 MFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQN 274
Query: 273 ACPILFKAQW--FIVLAVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+ F + + +++L + NS ++P+IY L S+E+R+ F ++C
Sbjct: 275 PYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIIC 318
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 107 bits (267), Expect = 2e-23
Identities = 78/285 (27%), Positives = 140/285 (49%), Gaps = 29/285 (10%)
Query: 47 LVIC---SFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVN---ILMSG 100
+V+C + + EN +V+ I F M+ +G+LA+ DLLAG+ ++ + G
Sbjct: 45 VVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIG 104
Query: 101 KKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIK-MRPYDANKRHRVFLLIG 159
SL + G + +A AS SLLAI ++R+L++ + Y R ++++
Sbjct: 105 SAEMSL------VLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLA 158
Query: 160 MCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIY 219
+ W A LG LP+L WNCL L C + PL SK ++ F + ++ LYA+I
Sbjct: 159 LVWGGALGLGLLPVLAWNCLDGLTTCGVVYPL-SKNHLVVLAIAFFMVFGIMLQLYAQIC 217
Query: 220 FLVKSSSRKV--------ANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRV 271
+V ++++ A+H + R + T+ +V+ F ACW P + L+ A
Sbjct: 218 RIVCRHAQQIALQRHLLPASHYVATRKG--IATLAVVLGAFAACWLPFTVYCLLGDA--- 272
Query: 272 QACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC 316
P L+ ++ A NS +NP+IY ++++++ + + C C
Sbjct: 273 -HSPPLY-TYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCC 315
>gi|170671732 melanocortin 3 receptor [Homo sapiens]
Length = 323
Score = 105 bits (262), Expect = 7e-23
Identities = 73/289 (25%), Positives = 140/289 (48%), Gaps = 32/289 (11%)
Query: 45 LFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILM-----S 99
+FL + +LEN++V++A+ +N H+ MYFF+ +LA+ D+L ++ + +M S
Sbjct: 44 VFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHS 103
Query: 100 GKKTF--SLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMI-KMRPYDANKRHRVFL 156
TF + + + + ++L AS C+LLAIA++R++T+ +R + +
Sbjct: 104 DYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALT 163
Query: 157 LIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYA 216
LI W+ G + I+ SK I I++F A+++ + LY
Sbjct: 164 LIVAIWVCCGVCGVV---------------FIVYSESKMVIVCLITMFFAMMLLMGTLYV 208
Query: 217 RIYFLVKSSSRKVAN-------HNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVAC 269
++ + +++A M T+ I++ VFI CW+P F+ ++ + C
Sbjct: 209 HMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITC 268
Query: 270 RVQACPILFKAQW--FIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC 316
I + A + ++VL + NS ++P+IY S E+R F ++C C
Sbjct: 269 PTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGC 317
>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
Length = 360
Score = 102 bits (255), Expect = 4e-22
Identities = 81/304 (26%), Positives = 140/304 (46%), Gaps = 17/304 (5%)
Query: 40 TLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILM 98
T VL ++ LEN+ VL I +++ + Y FIG+LA D LA + + + +
Sbjct: 34 TAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVN 93
Query: 99 SGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLL 157
S V+ L+ GS+ + AS SLL AI+R+L + Y A R R +
Sbjct: 94 FHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVT 153
Query: 158 IGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYAR 217
+G+ W+++ + LP++GW C CS + PL Y+ + + I+ Y
Sbjct: 154 LGIMWVLSALVSYLPLMGWTCCPR--PCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGH 211
Query: 218 IYFLVKSSSRKVANHNNSE--------RSMALLRTVVIVVSVFIACWSPLFILFLIDVAC 269
+ + ++ H + + + L +T+ +V++V + CW P+ L +A
Sbjct: 212 VLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLAT 271
Query: 270 RVQACPILFKAQWFI-VLAVLNSAMNPVIYTLASKEMRRAFFRLVCNC--LVRGRGARAS 326
+ + KA F +L ++NS +NPVIY L S E+R + + + VRG G+ A
Sbjct: 272 TLS--DQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAK 329
Query: 327 PIQP 330
P
Sbjct: 330 EEAP 333
>gi|4505127 melanocortin 2 receptor [Homo sapiens]
Length = 297
Score = 98.6 bits (244), Expect = 8e-21
Identities = 83/282 (29%), Positives = 139/282 (49%), Gaps = 33/282 (11%)
Query: 45 LFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKV--NILMSGKK 102
+F I VLENL+VL+A++KN MYFFI +LA+ D+L G YK+ NIL+ +
Sbjct: 30 IFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDML-GSLYKILENILIILRN 88
Query: 103 TFSLSPTVWFLREG-----SMFV-ALGASTCSLLAIAIERHLTMI-KMRPYDANKRHRVF 155
L P F S+FV +L S SL IA +R++T+ +R + R
Sbjct: 89 MGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTV 148
Query: 156 LLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILY 215
+++ + W G ++ H++P T S+F +LV I+ LY
Sbjct: 149 VVLTVIWTFCTGTGITMVI---FSHHVPTVITF------------TSLFPLMLVFILCLY 193
Query: 216 ARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQ--- 272
++ L +S +RK++ + A+ T+ I++ VFI CW+P + L+ C
Sbjct: 194 VHMFLLARSHTRKISTLPRANMKGAI--TLTILLGVFIFCWAPFVLHVLLMTFCPSNPYC 251
Query: 273 ACPI-LFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLV 313
AC + LF+ +++ N+ ++P IY S E+R AF +++
Sbjct: 252 ACYMSLFQVNGMLIMC--NAVIDPFIYAFRSPELRDAFKKMI 291
>gi|5921992 adenosine A2a receptor [Homo sapiens]
Length = 412
Score = 96.3 bits (238), Expect = 4e-20
Identities = 74/313 (23%), Positives = 142/313 (45%), Gaps = 39/313 (12%)
Query: 38 GSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNIL 97
GS++ + L I +L N++V A+W N+ N +F+ +LA D+ G+
Sbjct: 5 GSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGV------- 57
Query: 98 MSGKKTFSLSPTVWFLREGSMFVA------LGASTCSLLAIAIERHLTM-IKMRPYDANK 150
++ ++S G +F+A +S SLLAIAI+R++ + I +R
Sbjct: 58 LAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVT 117
Query: 151 RHRVFLLIGMCWLIAFTLGALPILGWN--------------CLHNLPDC--STILPLYSK 194
R +I +CW+++F +G P+LGWN C C ++P+
Sbjct: 118 GTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYM 177
Query: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVAN--------HNNSERSMALLRTVV 246
Y F + +L+ + + Y RI+ + +++ + + ++ + +++
Sbjct: 178 VYFNFFACVLVPLLLMLGV-YLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLA 236
Query: 247 IVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMR 306
I+V +F CW PL I+ C + L+ IVL+ NS +NP IY +E R
Sbjct: 237 IIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFR 296
Query: 307 RAFFRLVCNCLVR 319
+ F +++ + ++R
Sbjct: 297 QTFRKIIRSHVLR 309
>gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens]
Length = 318
Score = 92.8 bits (229), Expect = 4e-19
Identities = 73/298 (24%), Positives = 144/298 (48%), Gaps = 31/298 (10%)
Query: 41 LTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSG 100
+T +F+ +C+ ++ N++V+ + N ++FI +LAL D+ G+ ++M
Sbjct: 16 ITMEIFIGLCA--IVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGV-----LVMPL 68
Query: 101 KKTFSLSPTVWF----LREGSMFVALGASTCSLLAIAIERHLTM-IKMRPYDANKRHRVF 155
SL T+ F + + AS SLLAIA++R+L + + +R R++
Sbjct: 69 AIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIW 128
Query: 156 LLIGMCWLIAFTLGALPILGWNCL------HNLPDCS----TILPLYSKKYIAFCISIFT 205
L +G+CWL++F +G P+ GWN N+ S +++ + Y +F IF
Sbjct: 129 LALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFI 188
Query: 206 AILVTIVILYARIYFLVKSS-SRKVANHNNS----ERSMALLRTVVIVVSVFIACWSPLF 260
LV + +Y I++++++ S ++N + R +++ +V+ +F W PL
Sbjct: 189 P-LVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLS 247
Query: 261 ILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
I+ I +L+ I+L+ NS MNP++Y K+ + + ++ C+V
Sbjct: 248 IINCIIYFNGEVPQLVLYMG---ILLSHANSMMNPIVYAYKIKKFKETYLLILKACVV 302
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 84.7 bits (208), Expect = 1e-16
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 57/328 (17%)
Query: 34 EASEGSTLTTVLFLVICSFI---VLENLMVLIAI-WKNNKFHNRMYFFIGNLALCDLLAG 89
E GS VL + + I +L NL+V++A+ W + +FI +LA DLL
Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL-- 68
Query: 90 IAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDA- 148
V++L+ L +W G +F + S LL A HL I + Y A
Sbjct: 69 ----VSVLVMPFGAIELVQDIWIY--GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAI 122
Query: 149 --------NKRH--RVFLLIGMCWLIAFTLGALPIL-GWNCL-----------HNLPDCS 186
NK R+ L++G CW+I + LPI+ GWN + + + +
Sbjct: 123 CCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNST 182
Query: 187 TILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKV---------------- 229
+ + +K Y C + F + +V+ Y RIY K + ++
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 242
Query: 230 ANHNNSERSMA---LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVL 286
A+ +++ R +T+ I++ F CW+P F+ ++D ++ A F+ L
Sbjct: 243 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA--FLWL 300
Query: 287 AVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+NS +NP +Y +K RRAF ++C
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILC 328
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 84.7 bits (208), Expect = 1e-16
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 57/328 (17%)
Query: 34 EASEGSTLTTVLFLVICSFI---VLENLMVLIAI-WKNNKFHNRMYFFIGNLALCDLLAG 89
E GS VL + + I +L NL+V++A+ W + +FI +LA DLL
Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL-- 68
Query: 90 IAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDA- 148
V++L+ L +W G +F + S LL A HL I + Y A
Sbjct: 69 ----VSVLVMPFGAIELVQDIWIY--GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAI 122
Query: 149 --------NKRH--RVFLLIGMCWLIAFTLGALPIL-GWNCL-----------HNLPDCS 186
NK R+ L++G CW+I + LPI+ GWN + + + +
Sbjct: 123 CCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNST 182
Query: 187 TILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKV---------------- 229
+ + +K Y C + F + +V+ Y RIY K + ++
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 242
Query: 230 ANHNNSERSMA---LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVL 286
A+ +++ R +T+ I++ F CW+P F+ ++D ++ A F+ L
Sbjct: 243 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA--FLWL 300
Query: 287 AVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+NS +NP +Y +K RRAF ++C
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILC 328
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 84.7 bits (208), Expect = 1e-16
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 57/328 (17%)
Query: 34 EASEGSTLTTVLFLVICSFI---VLENLMVLIAI-WKNNKFHNRMYFFIGNLALCDLLAG 89
E GS VL + + I +L NL+V++A+ W + +FI +LA DLL
Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL-- 68
Query: 90 IAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDA- 148
V++L+ L +W G +F + S LL A HL I + Y A
Sbjct: 69 ----VSVLVMPFGAIELVQDIWIY--GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAI 122
Query: 149 --------NKRH--RVFLLIGMCWLIAFTLGALPIL-GWNCL-----------HNLPDCS 186
NK R+ L++G CW+I + LPI+ GWN + + + +
Sbjct: 123 CCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNST 182
Query: 187 TILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKV---------------- 229
+ + +K Y C + F + +V+ Y RIY K + ++
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 242
Query: 230 ANHNNSERSMA---LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVL 286
A+ +++ R +T+ I++ F CW+P F+ ++D ++ A F+ L
Sbjct: 243 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA--FLWL 300
Query: 287 AVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+NS +NP +Y +K RRAF ++C
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILC 328
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 84.7 bits (208), Expect = 1e-16
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 57/328 (17%)
Query: 34 EASEGSTLTTVLFLVICSFI---VLENLMVLIAI-WKNNKFHNRMYFFIGNLALCDLLAG 89
E GS VL + + I +L NL+V++A+ W + +FI +LA DLL
Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL-- 68
Query: 90 IAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDA- 148
V++L+ L +W G +F + S LL A HL I + Y A
Sbjct: 69 ----VSVLVMPFGAIELVQDIWIY--GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAI 122
Query: 149 --------NKRH--RVFLLIGMCWLIAFTLGALPIL-GWNCL-----------HNLPDCS 186
NK R+ L++G CW+I + LPI+ GWN + + + +
Sbjct: 123 CCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNST 182
Query: 187 TILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKV---------------- 229
+ + +K Y C + F + +V+ Y RIY K + ++
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 242
Query: 230 ANHNNSERSMA---LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVL 286
A+ +++ R +T+ I++ F CW+P F+ ++D ++ A F+ L
Sbjct: 243 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA--FLWL 300
Query: 287 AVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+NS +NP +Y +K RRAF ++C
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILC 328
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 84.7 bits (208), Expect = 1e-16
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 57/328 (17%)
Query: 34 EASEGSTLTTVLFLVICSFI---VLENLMVLIAI-WKNNKFHNRMYFFIGNLALCDLLAG 89
E GS VL + + I +L NL+V++A+ W + +FI +LA DLL
Sbjct: 11 EEGFGSVEKVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLL-- 68
Query: 90 IAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDA- 148
V++L+ L +W G +F + S LL A HL I + Y A
Sbjct: 69 ----VSVLVMPFGAIELVQDIWIY--GEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAI 122
Query: 149 --------NKRH--RVFLLIGMCWLIAFTLGALPIL-GWNCL-----------HNLPDCS 186
NK R+ L++G CW+I + LPI+ GWN + + + +
Sbjct: 123 CCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNST 182
Query: 187 TILPLYSKKYIAFC-ISIFTAILVTIVILYARIYFLVKSSSRKV---------------- 229
+ + +K Y C + F + +V+ Y RIY K + ++
Sbjct: 183 YCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQS 242
Query: 230 ANHNNSERSMA---LLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVL 286
A+ +++ R +T+ I++ F CW+P F+ ++D ++ A F+ L
Sbjct: 243 ADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTA--FLWL 300
Query: 287 AVLNSAMNPVIYTLASKEMRRAFFRLVC 314
+NS +NP +Y +K RRAF ++C
Sbjct: 301 GYINSGLNPFLYAFLNKSFRRAFLIILC 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.138 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,082,305
Number of Sequences: 37866
Number of extensions: 521534
Number of successful extensions: 3802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 419
Number of HSP's successfully gapped in prelim test: 275
Number of HSP's that attempted gapping in prelim test: 2580
Number of HSP's gapped (non-prelim): 884
length of query: 378
length of database: 18,247,518
effective HSP length: 104
effective length of query: 274
effective length of database: 14,309,454
effective search space: 3920790396
effective search space used: 3920790396
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.