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Search of human proteins with 38605733
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38605733 nucleoporin 43kDa [Homo sapiens]
(380 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38605733 nucleoporin 43kDa [Homo sapiens] 793 0.0
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 57 2e-08
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 57 2e-08
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 57 2e-08
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 57 3e-08
gi|14149987 WD repeat domain 24 [Homo sapiens] 55 1e-07
gi|84626578 G protein beta subunit-like [Homo sapiens] 54 2e-07
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 51 2e-06
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 51 2e-06
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 51 2e-06
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 50 3e-06
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 50 3e-06
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 50 4e-06
gi|4507703 tumor suppressing subtransferable candidate 1 [Homo s... 48 1e-05
gi|58331266 WD repeat domain 59 [Homo sapiens] 48 2e-05
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 47 4e-05
gi|32483359 apoptotic peptidase activating factor 1 isoform c [H... 47 4e-05
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 47 4e-05
gi|7108333 apoptotic peptidase activating factor 1 isoform a [Ho... 47 4e-05
gi|57165359 WD repeat domain 89 [Homo sapiens] 47 4e-05
gi|18087841 WD repeat domain 89 [Homo sapiens] 47 4e-05
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 46 6e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens] 44 2e-04
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 44 2e-04
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 44 2e-04
gi|89886480 zinedin isoform 2 [Homo sapiens] 44 3e-04
gi|89886477 zinedin isoform 1 [Homo sapiens] 44 3e-04
gi|34996489 pleckstrin homology domain interacting protein [Homo... 44 3e-04
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 43 4e-04
gi|157384986 transducin-like enhancer protein 3 isoform b [Homo ... 43 5e-04
>gi|38605733 nucleoporin 43kDa [Homo sapiens]
Length = 380
Score = 793 bits (2048), Expect = 0.0
Identities = 380/380 (100%), Positives = 380/380 (100%)
Query: 1 MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGG 60
MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGG
Sbjct: 1 MEEIYAKFVSQKISKTRWRPLPPGSLQTAETFATGSWDNEENYISLWSIGDFGNLDSDGG 60
Query: 61 FEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHY 120
FEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHY
Sbjct: 61 FEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTVFLHHPNNQTLSVNQQWTTAHY 120
Query: 121 HTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTF 180
HTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTF
Sbjct: 121 HTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTF 180
Query: 181 LRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDG 240
LRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDG
Sbjct: 181 LRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDG 240
Query: 241 MLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSS 300
MLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSS
Sbjct: 241 MLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSS 300
Query: 301 LFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLG 360
LFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLG
Sbjct: 301 LFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLLPSRSLSVNTLDVLG 360
Query: 361 PCLVCGTDAEAIYVTRHLFS 380
PCLVCGTDAEAIYVTRHLFS
Sbjct: 361 PCLVCGTDAEAIYVTRHLFS 380
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 57.4 bits (137), Expect = 2e-08
Identities = 69/303 (22%), Positives = 121/303 (39%), Gaps = 35/303 (11%)
Query: 50 GDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTV----FLHHPN 105
G+FG G G ++ I H G+V ++ Q + A+ T V + HP+
Sbjct: 68 GEFGGF---GSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 124
Query: 106 NQTLSVN---QQWTTAHYHTGPG---SPSYS----SAPCTGVVCNNPEIVTVGEDGRINL 155
S H G G +P+ S SA +C +I V ++G++
Sbjct: 125 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLW-DISAVPKEGKVVD 183
Query: 156 FRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQG-NEPSQILSLT 214
+ +++ LH F +V +L IWD R ++PS S+
Sbjct: 184 AKTIFTGHTAVVEDVSWHLLHESLFG------SVADDQKLMIWDTRSNNTSKPSH--SVD 235
Query: 215 GDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNP 274
++C+ +P + ++ATG D +++WD+R + + ++H+ E+++V + P N
Sbjct: 236 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 295
Query: 275 EHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVIS--SWLS 332
L + D L WD S E+S + G H H + IS SW
Sbjct: 296 TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH------GGHTAKISDFSWNP 349
Query: 333 TDP 335
+P
Sbjct: 350 NEP 352
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 57.4 bits (137), Expect = 2e-08
Identities = 69/303 (22%), Positives = 121/303 (39%), Gaps = 35/303 (11%)
Query: 50 GDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTV----FLHHPN 105
G+FG G G ++ I H G+V ++ Q + A+ T V + HP+
Sbjct: 102 GEFGGF---GSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 158
Query: 106 NQTLSVN---QQWTTAHYHTGPG---SPSYS----SAPCTGVVCNNPEIVTVGEDGRINL 155
S H G G +P+ S SA +C +I V ++G++
Sbjct: 159 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLW-DISAVPKEGKVVD 217
Query: 156 FRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQG-NEPSQILSLT 214
+ +++ LH F +V +L IWD R ++PS S+
Sbjct: 218 AKTIFTGHTAVVEDVSWHLLHESLFG------SVADDQKLMIWDTRSNNTSKPSH--SVD 269
Query: 215 GDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNP 274
++C+ +P + ++ATG D +++WD+R + + ++H+ E+++V + P N
Sbjct: 270 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 329
Query: 275 EHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVIS--SWLS 332
L + D L WD S E+S + G H H + IS SW
Sbjct: 330 TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH------GGHTAKISDFSWNP 383
Query: 333 TDP 335
+P
Sbjct: 384 NEP 386
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 57.4 bits (137), Expect = 2e-08
Identities = 69/303 (22%), Positives = 121/303 (39%), Gaps = 35/303 (11%)
Query: 50 GDFGNLDSDGGFEGDHQLLCDIRHHGDVMDLQFFDQERIVAASSTGCVTV----FLHHPN 105
G+FG G G ++ I H G+V ++ Q + A+ T V + HP+
Sbjct: 103 GEFGGF---GSVSGKIEIEIKINHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPS 159
Query: 106 NQTLSVN---QQWTTAHYHTGPG---SPSYS----SAPCTGVVCNNPEIVTVGEDGRINL 155
S H G G +P+ S SA +C +I V ++G++
Sbjct: 160 KPDPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLW-DISAVPKEGKVVD 218
Query: 156 FRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQG-NEPSQILSLT 214
+ +++ LH F +V +L IWD R ++PS S+
Sbjct: 219 AKTIFTGHTAVVEDVSWHLLHESLFG------SVADDQKLMIWDTRSNNTSKPSH--SVD 270
Query: 215 GDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNP 274
++C+ +P + ++ATG D +++WD+R + + ++H+ E+++V + P N
Sbjct: 271 AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQVQWSPHNE 330
Query: 275 EHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSHSISNQANVHQSVIS--SWLS 332
L + D L WD S E+S + G H H + IS SW
Sbjct: 331 TILASSGTDRRLNVWDLSKIGEEQSPEDAEDGPPELLFIH------GGHTAKISDFSWNP 384
Query: 333 TDP 335
+P
Sbjct: 385 NEP 387
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/145 (26%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 194 QLKIWDFRQQG-NEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTM 252
+L IWD R ++PS ++ ++C+ +P + ++ATG D +++WD+R +
Sbjct: 250 KLMIWDTRSNTTSKPSHLVD--AHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKL 307
Query: 253 PVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFL 312
+ ++H+ E+++VH+ P N L + D L WD S E+S+ + G
Sbjct: 308 KLHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLF 367
Query: 313 SHSISNQANVHQSVIS--SWLSTDP 335
H H + IS SW +P
Sbjct: 368 IH------GGHTAKISDFSWNPNEP 386
Score = 35.8 bits (81), Expect = 0.066
Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 5/99 (5%)
Query: 197 IWDFR---QQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGT-- 251
+WD ++G TG + V H + + + D L IWD R T
Sbjct: 203 LWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTS 262
Query: 252 MPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
P L+ AH AE+ + F+P + L T S D ++ WD
Sbjct: 263 KPSHLVDAHTAEVNCLSFNPYSEFILATGSADKTVALWD 301
>gi|14149987 WD repeat domain 24 [Homo sapiens]
Length = 790
Score = 54.7 bits (130), Expect = 1e-07
Identities = 42/162 (25%), Positives = 69/162 (42%), Gaps = 14/162 (8%)
Query: 138 VCNNPE----IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSI- 192
VC +P +++ +DG + F K++V T S +R + T S
Sbjct: 126 VCFHPTEAHVLLSGSQDGFMKCFDLRRKDSVSTFSGQSESVRDVQFSIR--DYFTFASTF 183
Query: 193 --GQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQG 250
G +++WD R+ + G P+ C D HP + +ATGG+D M+ +WD+
Sbjct: 184 ENGNVQLWDIRRPDRCERMFTAHNG---PVFCCDWHPEDRGWLATGGRDKMVKVWDMTTH 240
Query: 251 TMPVSLLKAHEAEMWEVHFHPSNPEHLFTCS--EDGSLWHWD 290
A + V + P HL TCS D +++ WD
Sbjct: 241 RAKEMHCVQTIASVARVKWRPECRHHLATCSMMVDHNIYVWD 282
Score = 33.9 bits (76), Expect = 0.25
Identities = 22/108 (20%), Positives = 48/108 (44%), Gaps = 4/108 (3%)
Query: 186 ILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIW 245
+L+ + G +K +D R++ + + + +G + V A+ ++G + +W
Sbjct: 136 LLSGSQDGFMKCFDLRRKDS----VSTFSGQSESVRDVQFSIRDYFTFASTFENGNVQLW 191
Query: 246 DVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDAST 293
D+R+ + AH ++ +HP + L T D + WD +T
Sbjct: 192 DIRRPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMTT 239
Score = 30.0 bits (66), Expect = 3.6
Identities = 19/75 (25%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 220 LHCVDR--HPNQQHVVATGGQDGMLSIWDVRQGTMPVS--LLKAHEAEMWEVHFHPSNPE 275
L C D H ++++AT +G++ W++ + + L H+ + +V FHP+
Sbjct: 75 LSCADVVWHQMDENLLATAATNGVVVTWNLGRPSRNKQDQLFTEHKRTVNKVCFHPTEAH 134
Query: 276 HLFTCSEDGSLWHWD 290
L + S+DG + +D
Sbjct: 135 VLLSGSQDGFMKCFD 149
>gi|84626578 G protein beta subunit-like [Homo sapiens]
Length = 326
Score = 53.9 bits (128), Expect = 2e-07
Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 9/222 (4%)
Query: 136 GVVCNNPEIV-TVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQ 194
G V ++P I+ T G D + ++A RT+ + DS ++A+ TP+ + + G
Sbjct: 6 GTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQ-VNALEV--TPDRSMIAAAGY 62
Query: 195 LKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPV 254
I + N P+ I+S G + V H + + + TGG+D IWD+R +
Sbjct: 63 QHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMY-TGGEDCTARIWDLRSRNLQC 121
Query: 255 SLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSH 314
+ A + V HP+ E L + G++ WD TD E+ + +S +
Sbjct: 122 QRIFQVNAPINCVCLHPNQAE-LIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDP 180
Query: 315 SISNQANVHQS-VISSWLSTDPAKDRIEITSLLPSRSLSVNT 355
S A V+ + W T D E+T L+P + +T
Sbjct: 181 DASYMAAVNSTGNCYVWNLTGGIGD--EVTQLIPKTKIPAHT 220
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/154 (22%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
Query: 140 NNPEIVTVG-EDGRINLF--RADHKEAVRTIDNADSSTLHAV-TFLRTPEILTVNSIGQL 195
NN +++ G ED + ++ + ++ + H + LR + + + G +
Sbjct: 508 NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTV 567
Query: 196 KIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVS 255
+IWD+ Q + I L G P+ + + +++ +G D + +WD R+GT V
Sbjct: 568 RIWDYTQD----ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTC-VD 622
Query: 256 LLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHW 289
+ H A+++ + HPS P + +CS D ++ W
Sbjct: 623 TVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 656
Score = 35.4 bits (80), Expect = 0.086
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 224 DRHPNQQHVVATGGQDGMLSIWDVRQGT-MPVSLLKAHEAEMWEVHFHPSNPEHLFTCSE 282
D N + ++ATG +D + ++ V + P+ + H A+++ V + P L + S+
Sbjct: 504 DWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSD 563
Query: 283 DGSLWHWDASTD 294
DG++ WD + D
Sbjct: 564 DGTVRIWDYTQD 575
Score = 29.3 bits (64), Expect = 6.1
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 239 DGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDAST 293
DG + ++D+ H +++ F P +P L T S DG++ WD +T
Sbjct: 347 DGGVGLYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINT 401
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 51.2 bits (121), Expect = 2e-06
Identities = 35/154 (22%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
Query: 140 NNPEIVTVG-EDGRINLF--RADHKEAVRTIDNADSSTLHAV-TFLRTPEILTVNSIGQL 195
NN +++ G ED + ++ + ++ + H + LR + + + G +
Sbjct: 532 NNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTV 591
Query: 196 KIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVS 255
+IWD+ Q + I L G P+ + + +++ +G D + +WD R+GT V
Sbjct: 592 RIWDYTQD----ACINILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWDTREGTC-VD 646
Query: 256 LLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHW 289
+ H A+++ + HPS P + +CS D ++ W
Sbjct: 647 TVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLW 680
Score = 35.4 bits (80), Expect = 0.086
Identities = 19/72 (26%), Positives = 38/72 (52%), Gaps = 1/72 (1%)
Query: 224 DRHPNQQHVVATGGQDGMLSIWDVRQGT-MPVSLLKAHEAEMWEVHFHPSNPEHLFTCSE 282
D N + ++ATG +D + ++ V + P+ + H A+++ V + P L + S+
Sbjct: 528 DWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSD 587
Query: 283 DGSLWHWDASTD 294
DG++ WD + D
Sbjct: 588 DGTVRIWDYTQD 599
Score = 29.3 bits (64), Expect = 6.1
Identities = 15/55 (27%), Positives = 26/55 (47%)
Query: 239 DGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDAST 293
DG + ++D+ H +++ F P +P L T S DG++ WD +T
Sbjct: 371 DGGVGLYDMGAKKWDFLRDLGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINT 425
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 50.8 bits (120), Expect = 2e-06
Identities = 44/208 (21%), Positives = 80/208 (38%), Gaps = 30/208 (14%)
Query: 121 HTGPG-----SPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTL 175
H G G SP + TG N + T + G ++ + R++++ S
Sbjct: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
Query: 176 HAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVAT 235
F + ++ ++IWD R ++ + + T ++ + ++ + +
Sbjct: 273 ENTVFA------SCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVIS-WSRREPFLLS 325
Query: 236 GGQDGMLSIWDVRQ--GTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDAS- 292
GG DG L IWD+RQ PV+ K H A + V +HP + D + WD +
Sbjct: 326 GGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAV 385
Query: 293 ---------------TDVPEKSSLFHQG 305
D+P++ HQG
Sbjct: 386 ERDPEAGDVEADPGLADLPQQLLFVHQG 413
Score = 48.9 bits (115), Expect = 7e-06
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 19/145 (13%)
Query: 158 ADHKEAVRTIDNADSSTLHAVTFLRT-PEILTVNSIGQLKIWDFRQQGNEPSQILSLTGD 216
A K + T A ++ +++ R P +L+ G LKIWD RQ S + +
Sbjct: 294 APSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQF-KSGSPVATFKQH 352
Query: 217 RVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQ---------------GTMPVSLLKAH- 260
P+ V+ HP V A G D ++ WD+ +P LL H
Sbjct: 353 VAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQ 412
Query: 261 -EAEMWEVHFHPSNPEHLFTCSEDG 284
E E+ E+H+HP P L + + G
Sbjct: 413 GETELKELHWHPQCPGLLVSTALSG 437
>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit
isoform a [Homo sapiens]
Length = 353
Score = 50.1 bits (118), Expect = 3e-06
Identities = 55/216 (25%), Positives = 95/216 (43%), Gaps = 23/216 (10%)
Query: 84 DQERIVAASSTGCVTVFLHHPNNQTLSVNQQ--WTTAHYHTGPGSPSYSSAPCTGVVCNN 141
D+ RIV++S G V V+ N+ +V W A + +PS + C G+ N
Sbjct: 74 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAY----APSGCAIACGGLD-NK 128
Query: 142 PEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTP-EILTVNSIGQLKIWDF 200
+ + D N+ A+ T + L A +F + +ILT + G +WD
Sbjct: 129 CSVYPLTFDKNENMAAKKKSVAMHT------NYLSACSFTNSDMQILTASGDGTCALWDV 182
Query: 201 RQQGNEPSQIL-SLTGDRVPLHCVDRHPNQQ-HVVATGGQDGMLSIWDVRQGTMPVSLLK 258
E Q+L S G + C+D P++ + +GG D +WD+R G V +
Sbjct: 183 -----ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQC-VQAFE 236
Query: 259 AHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTD 294
HE+++ V ++PS + + S+D + +D D
Sbjct: 237 THESDINSVRYYPSG-DAFASGSDDATCRLYDLRAD 271
>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
isoform b [Homo sapiens]
Length = 395
Score = 50.1 bits (118), Expect = 3e-06
Identities = 55/216 (25%), Positives = 95/216 (43%), Gaps = 23/216 (10%)
Query: 84 DQERIVAASSTGCVTVFLHHPNNQTLSVNQQ--WTTAHYHTGPGSPSYSSAPCTGVVCNN 141
D+ RIV++S G V V+ N+ +V W A + +PS + C G+ N
Sbjct: 116 DKRRIVSSSQDGKVIVWDSFTTNKEHAVTMPCTWVMACAY----APSGCAIACGGLD-NK 170
Query: 142 PEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTP-EILTVNSIGQLKIWDF 200
+ + D N+ A+ T + L A +F + +ILT + G +WD
Sbjct: 171 CSVYPLTFDKNENMAAKKKSVAMHT------NYLSACSFTNSDMQILTASGDGTCALWDV 224
Query: 201 RQQGNEPSQIL-SLTGDRVPLHCVDRHPNQQ-HVVATGGQDGMLSIWDVRQGTMPVSLLK 258
E Q+L S G + C+D P++ + +GG D +WD+R G V +
Sbjct: 225 -----ESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQC-VQAFE 278
Query: 259 AHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTD 294
HE+++ V ++PS + + S+D + +D D
Sbjct: 279 THESDINSVRYYPSG-DAFASGSDDATCRLYDLRAD 313
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 49.7 bits (117), Expect = 4e-06
Identities = 41/150 (27%), Positives = 77/150 (51%), Gaps = 13/150 (8%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTV--NSIGQLKIWDFR 201
+ T G+D R+NL+ + + ++ +S + +V L TPE L V + G +++WD
Sbjct: 36 LATGGDDCRVNLWSINKPNCIMSL-TGHTSPVESVR-LNTPEELIVAGSQSGSIRVWDL- 92
Query: 202 QQGNEPSQIL-SLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAH 260
E ++IL +L G + + +D HP + V A+G QD + +WD+R+ V + H
Sbjct: 93 ----EAAKILRTLMGHKANICSLDFHPYGEFV-ASGSQDTNIKLWDIRRKGC-VFRYRGH 146
Query: 261 EAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
+ + F P + L + ++D ++ WD
Sbjct: 147 SQAVRCLRFSPDG-KWLASAADDHTVKLWD 175
Score = 29.3 bits (64), Expect = 6.1
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 4/60 (6%)
Query: 232 VVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTC-SEDGSLWHWD 290
++ATGG D +++W + + +S L H + + V + PE L S+ GS+ WD
Sbjct: 35 LLATGGDDCRVNLWSINKPNCIMS-LTGHTSPVESVRL--NTPEELIVAGSQSGSIRVWD 91
>gi|4507703 tumor suppressing subtransferable candidate 1 [Homo
sapiens]
Length = 387
Score = 48.1 bits (113), Expect = 1e-05
Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 6/100 (6%)
Query: 185 EILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPL-HCVDRHPNQQHVVATGGQDGMLS 243
++ T N L+ WD R SQI + L +D +PN+Q+ +A+ G D +
Sbjct: 200 QVATANDT-TLRGWDTRSM----SQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVK 254
Query: 244 IWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSED 283
WD R T PV L+ H +W V ++ S+ + + T S D
Sbjct: 255 FWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSD 294
Score = 30.8 bits (68), Expect = 2.1
Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 1/58 (1%)
Query: 233 VATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
VAT D L WD R + + AH + ++ F+P+ +L +C +D + WD
Sbjct: 201 VATAN-DTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWD 257
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 47.8 bits (112), Expect = 2e-05
Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 187 LTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWD 246
L + G ++IWD R+ + + L +H +D HP+ +H++AT QD + WD
Sbjct: 164 LATSHDGDVRIWDKRKPS---TAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWD 220
Query: 247 VRQGTMPVSLLKAHEAEMWEVHFHP 271
RQ +++L + +W+ + P
Sbjct: 221 YRQPRKYLNILPC-QVPVWKARYTP 244
Score = 45.4 bits (106), Expect = 8e-05
Identities = 31/108 (28%), Positives = 54/108 (50%), Gaps = 6/108 (5%)
Query: 184 PEILTVNSIGQ-LKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGML 242
P++L +S+ + IWD + +P+ LS + ++ N +AT DG +
Sbjct: 118 PDLLVTSSVDTYIYIWDIKDT-RKPTVALSAVAGASQVKWNKKNAN---CLATS-HDGDV 172
Query: 243 SIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
IWD R+ + V L AH +++ + +HP + L T S+D S+ WD
Sbjct: 173 RIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWD 220
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQ 203
I + G D + +F+A+ E + I + L I T + ++KIW+
Sbjct: 630 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---- 685
Query: 204 GNEPSQILSLTGDRVPLHCVDRHPNQQH-----------VVATGGQDGMLSIWDVRQGTM 252
S+TG+ V H D H Q + ++ATG D L +WD+ Q
Sbjct: 686 --------SMTGELV--HTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC 735
Query: 253 PVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKS 299
++ H + F P + + L +CS DG+L WDA++ KS
Sbjct: 736 RNTMF-GHTNSVNHCRFSPDD-KLLASCSADGTLKLWDATSANERKS 780
>gi|32483359 apoptotic peptidase activating factor 1 isoform c [Homo
sapiens]
Length = 1248
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQ 203
I + G D + +F+A+ E + I + L I T + ++KIW+
Sbjct: 630 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---- 685
Query: 204 GNEPSQILSLTGDRVPLHCVDRHPNQQH-----------VVATGGQDGMLSIWDVRQGTM 252
S+TG+ V H D H Q + ++ATG D L +WD+ Q
Sbjct: 686 --------SMTGELV--HTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC 735
Query: 253 PVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKS 299
++ H + F P + + L +CS DG+L WDA++ KS
Sbjct: 736 RNTMF-GHTNSVNHCRFSPDD-KLLASCSADGTLKLWDATSANERKS 780
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQ 203
I + G D + +F+A+ E + I + L I T + ++KIW+
Sbjct: 619 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---- 674
Query: 204 GNEPSQILSLTGDRVPLHCVDRHPNQQH-----------VVATGGQDGMLSIWDVRQGTM 252
S+TG+ V H D H Q + ++ATG D L +WD+ Q
Sbjct: 675 --------SMTGELV--HTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC 724
Query: 253 PVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKS 299
++ H + F P + + L +CS DG+L WDA++ KS
Sbjct: 725 RNTMF-GHTNSVNHCRFSPDD-KLLASCSADGTLKLWDATSANERKS 769
>gi|7108333 apoptotic peptidase activating factor 1 isoform a [Homo
sapiens]
Length = 1237
Score = 46.6 bits (109), Expect = 4e-05
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 27/167 (16%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQ 203
I + G D + +F+A+ E + I + L I T + ++KIW+
Sbjct: 619 IASCGADKTLQVFKAETGEKLLEIKAHEDEVLCCAFSTDDRFIATCSVDKKVKIWN---- 674
Query: 204 GNEPSQILSLTGDRVPLHCVDRHPNQQH-----------VVATGGQDGMLSIWDVRQGTM 252
S+TG+ V H D H Q + ++ATG D L +WD+ Q
Sbjct: 675 --------SMTGELV--HTYDEHSEQVNCCHFTNSSHHLLLATGSSDCFLKLWDLNQKEC 724
Query: 253 PVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKS 299
++ H + F P + + L +CS DG+L WDA++ KS
Sbjct: 725 RNTMF-GHTNSVNHCRFSPDD-KLLASCSADGTLKLWDATSANERKS 769
>gi|57165359 WD repeat domain 89 [Homo sapiens]
Length = 387
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 24/171 (14%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPE-ILTVNSIGQLKIWDFRQ 202
+ + +G I ++ + +R L+ V F + + + + + G +K WD R
Sbjct: 43 VAVLCSNGSIRIYDKERLNVLREFSGYPG-LLNGVRFANSCDSVYSACTDGTVKCWDARV 101
Query: 203 QGNEPSQILSLTGDRV----PLHCVDRHPNQQHVVATGGQ----DGMLSIWDVRQGTMPV 254
+P Q+ + ++C D H++ G + D +L WD R + +
Sbjct: 102 AREKPVQLFKGYPSNIFISFDINCND------HIICAGTEKVDDDALLVFWDARMNSQNL 155
Query: 255 SLLK--------AHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPE 297
S K H ++ +V FHPSNP + + S DG + +D + D E
Sbjct: 156 STTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEE 206
>gi|18087841 WD repeat domain 89 [Homo sapiens]
Length = 387
Score = 46.6 bits (109), Expect = 4e-05
Identities = 38/171 (22%), Positives = 71/171 (41%), Gaps = 24/171 (14%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPE-ILTVNSIGQLKIWDFRQ 202
+ + +G I ++ + +R L+ V F + + + + + G +K WD R
Sbjct: 43 VAVLCSNGSIRIYDKERLNVLREFSGYPG-LLNGVRFANSCDSVYSACTDGTVKCWDARV 101
Query: 203 QGNEPSQILSLTGDRV----PLHCVDRHPNQQHVVATGGQ----DGMLSIWDVRQGTMPV 254
+P Q+ + ++C D H++ G + D +L WD R + +
Sbjct: 102 AREKPVQLFKGYPSNIFISFDINCND------HIICAGTEKVDDDALLVFWDARMNSQNL 155
Query: 255 SLLK--------AHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPE 297
S K H ++ +V FHPSNP + + S DG + +D + D E
Sbjct: 156 STTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEE 206
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 45.8 bits (107), Expect = 6e-05
Identities = 41/165 (24%), Positives = 72/165 (43%), Gaps = 13/165 (7%)
Query: 134 CTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTP----EILTV 189
C V P I+T +D I L+ D K + + + T + + + P + +
Sbjct: 104 CIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQV--FEGHTHYVMQIVINPKDNNQFASA 161
Query: 190 NSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPN-QQHVVATGGQDGMLSIWDVR 248
+ +K+W Q S +L G ++C+D + + + +G D ++ IWD +
Sbjct: 162 SLDRTIKVW----QLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQ 217
Query: 249 QGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDAST 293
T V L+ H + FHP P + T SEDG++ W +ST
Sbjct: 218 NKTC-VQTLEGHAQNVSCASFHPELPI-IITGSEDGTVRIWHSST 260
Score = 31.2 bits (69), Expect = 1.6
Identities = 23/102 (22%), Positives = 45/102 (44%), Gaps = 8/102 (7%)
Query: 105 NNQTLSVNQQWTTAHYHTGPGSPSYS-SAPCTGVVC-------NNPEIVTVGEDGRINLF 156
NNQ S + T + G SP+++ GV C + P +++ +D + ++
Sbjct: 155 NNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIW 214
Query: 157 RADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIW 198
+K V+T++ + A P I+T + G ++IW
Sbjct: 215 DYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIW 256
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/148 (27%), Positives = 68/148 (45%), Gaps = 9/148 (6%)
Query: 145 VTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQ-LKIWDFRQQ 203
V+ G D L+ DH + +R I + ++ F + S + +++WD
Sbjct: 601 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLN- 658
Query: 204 GNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAE 263
GN + TG + P+H + PN + + ATG DG + +WD+ G M V LK H
Sbjct: 659 GN---CVRIFTGHKGPIHSLTFSPNGRFL-ATGATDGRVLLWDIGHGLM-VGELKGHTDT 713
Query: 264 MWEVHFHPSNPEHLFTCSEDGSLWHWDA 291
+ + F + E L + S D ++ WDA
Sbjct: 714 VCSLRF-SRDGEILASGSMDNTVRLWDA 740
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/175 (21%), Positives = 70/175 (40%), Gaps = 7/175 (4%)
Query: 116 TTAHYHTGPGSPSYSSAPCTGVVCNNPEIVTVGEDGRINLFRADHKEAVRTIDNADSSTL 175
T ++T G+ + + + + + DG + L+ D E V I+
Sbjct: 268 TLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVA 327
Query: 176 HAVTFLRTPEILTVNSIGQLKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVAT 235
+ + T ++WD Q +IL G + ++ + H + + T
Sbjct: 328 RVMWHPSGRFLGTTCYDRSWRLWDLEAQ----EEILHQEGHSMGVYDIAFHQDGS-LAGT 382
Query: 236 GGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
GG D +WD+R G + L+ H E++ ++F P N H+ T S D + WD
Sbjct: 383 GGLDAFGRVWDLRTGRC-IMFLEGHLKEIYGINFSP-NGYHIATGSGDNTCKVWD 435
Score = 42.4 bits (98), Expect = 7e-04
Identities = 31/110 (28%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 196 KIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVS 255
++WD R I+ L G ++ ++ PN H+ ATG D +WD+RQ V
Sbjct: 390 RVWDLRTG----RCIMFLEGHLKEIYGINFSPNGYHI-ATGSGDNTCKVWDLRQRRC-VY 443
Query: 256 LLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQG 305
+ AH+ + V F P + L T + D + W P K+ H+G
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEG 493
Score = 36.6 bits (83), Expect = 0.038
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 9/92 (9%)
Query: 212 SLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHP 271
S GD P+ PN + ++AT G+ +W V + + L+ H + + FHP
Sbjct: 226 SQIGDDRPISYCHFSPNSK-MLATACWSGLCKLWSVPDCNL-LHTLRGHNTNVGAIVFHP 283
Query: 272 SNPE-------HLFTCSEDGSLWHWDASTDVP 296
+ +L +C+ DGS+ W +D P
Sbjct: 284 KSTVSLDPKDVNLASCAADGSVKLWSLDSDEP 315
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 43.9 bits (102), Expect = 2e-04
Identities = 24/84 (28%), Positives = 45/84 (53%), Gaps = 2/84 (2%)
Query: 210 ILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHF 269
I+ L+G ++C HPN +A+ G D ++ +W+V + LK H + E+H+
Sbjct: 59 IMLLSGHEGEVYCCKFHPNGS-TLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHY 117
Query: 270 HPSNPEHLFTCSEDGSLWHWDAST 293
+ ++ LF+ S D ++ WD+ T
Sbjct: 118 N-TDGSMLFSASTDKTVAVWDSET 140
Score = 32.7 bits (73), Expect = 0.56
Identities = 29/161 (18%), Positives = 68/161 (42%), Gaps = 19/161 (11%)
Query: 144 IVTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRTPEILTVNSI-GQLKIWDFRQ 202
+ + D + ++ ++ E V+ + S R P+++ S G +K+WD R+
Sbjct: 124 LFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRK 183
Query: 203 QG-----NEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLL 257
+ Q+L++T + + + +GG D + +WD+RQ + + +
Sbjct: 184 KAAIQTFQNTYQVLAVTFN-----------DTSDQIISGGIDNDIKVWDLRQNKLTYT-M 231
Query: 258 KAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEK 298
+ H + + S +L + + D ++ WD P++
Sbjct: 232 RGHADSVTGLSL-SSEGSYLLSNAMDNTVRVWDVRPFAPKE 271
>gi|89886480 zinedin isoform 2 [Homo sapiens]
Length = 760
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/228 (21%), Positives = 88/228 (38%), Gaps = 32/228 (14%)
Query: 145 VTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRT-------PEILTVNSIGQLKI 197
+TV D ++ +D K+A + N + +R+ +LT + G LK+
Sbjct: 412 LTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKL 471
Query: 198 WDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVA---------TGGQDGMLSIWDVR 248
W+ ++ D P+H H VA +GG D + W +
Sbjct: 472 WNLQKAVTAKKNAAL---DVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIP 528
Query: 249 QGTMPV----------SLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEK 298
+M +L+ H +W + F P++ + L +CS DG++ WD S+ P
Sbjct: 529 DLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTS-QRLASCSADGTVRIWDPSSSSPAC 587
Query: 299 SSLFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLL 346
F S + ++ H +++S+ S D +E+ S L
Sbjct: 588 LCTFPTASEHGVPTSVAFTSTEPAH--IVASFRSGDTVLYDMEVGSAL 633
>gi|89886477 zinedin isoform 1 [Homo sapiens]
Length = 753
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/228 (21%), Positives = 88/228 (38%), Gaps = 32/228 (14%)
Query: 145 VTVGEDGRINLFRADHKEAVRTIDNADSSTLHAVTFLRT-------PEILTVNSIGQLKI 197
+TV D ++ +D K+A + N + +R+ +LT + G LK+
Sbjct: 405 LTVTNDNDLSCDLSDSKDAFKKTWNPKFTLRSHYDGIRSLAFHHSQSALLTASEDGTLKL 464
Query: 198 WDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVA---------TGGQDGMLSIWDVR 248
W+ ++ D P+H H VA +GG D + W +
Sbjct: 465 WNLQKAVTAKKNAAL---DVEPIHAFRAHRGPVLAVAMGSNSEYCYSGGADACIHSWKIP 521
Query: 249 QGTMPV----------SLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEK 298
+M +L+ H +W + F P++ + L +CS DG++ WD S+ P
Sbjct: 522 DLSMDPYDGYDPSVLSHVLEGHGDAVWGLAFSPTS-QRLASCSADGTVRIWDPSSSSPAC 580
Query: 299 SSLFHQGGRSSTFLSHSISNQANVHQSVISSWLSTDPAKDRIEITSLL 346
F S + ++ H +++S+ S D +E+ S L
Sbjct: 581 LCTFPTASEHGVPTSVAFTSTEPAH--IVASFRSGDTVLYDMEVGSAL 626
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 43.5 bits (101), Expect = 3e-04
Identities = 26/87 (29%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 213 LTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPS 272
+T +V + DRH N V T + L +W+ G + + +L HE E++ + HP
Sbjct: 422 ITKMKVTMVAWDRHDN---TVITAVNNMTLKVWNSYTGQL-IHVLMGHEDEVFVLEPHPF 477
Query: 273 NPEHLFTCSEDGSLWHWDASTDVPEKS 299
+P LF+ DG++ WD + V +S
Sbjct: 478 DPRVLFSAGHDGNVIVWDLARGVKIRS 504
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/118 (27%), Positives = 52/118 (44%), Gaps = 7/118 (5%)
Query: 196 KIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVS 255
++W F + P +I + G + CV HPN ++ ATG D + +W +QG V
Sbjct: 409 RLWSFDR--TYPLRIYA--GHLADVDCVKFHPNSNYL-ATGSTDKTVRLWSAQQGN-SVR 462
Query: 256 LLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLS 313
L H + + F P N ++L + ED L WD ++ K H +S S
Sbjct: 463 LFTGHRGPVLSLAFSP-NGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFS 519
Score = 39.3 bits (90), Expect = 0.006
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 7/96 (7%)
Query: 195 LKIWDFRQQGNEPSQILSLTGDRVPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPV 254
+++W QQGN + TG R P+ + PN +++ A+ G+D L +WD+ GT+
Sbjct: 450 VRLWS-AQQGNS---VRLFTGHRGPVLSLAFSPNGKYL-ASAGEDQRLKLWDLASGTL-Y 503
Query: 255 SLLKAHEAEMWEVHFHPSNPEHLFTCSEDGSLWHWD 290
L+ H + + F P + + + S D S+ WD
Sbjct: 504 KELRGHTDNITSLTFSPDS-GLIASASMDNSVRVWD 538
>gi|157384986 transducin-like enhancer protein 3 isoform b [Homo
sapiens]
Length = 769
Score = 42.7 bits (99), Expect = 5e-04
Identities = 37/157 (23%), Positives = 60/157 (38%), Gaps = 6/157 (3%)
Query: 160 HKEAVRTIDNADSSTLHAVTFLRTPEILTVNSIGQLKIWDFRQQGNEP--SQILSLTGDR 217
H + T+ + + + AVT + G +KIWD Q G++ SQ+ L D
Sbjct: 473 HARQINTLSHGE--VVCAVTISNPTRHVYTGGKGCVKIWDISQPGSKSPISQLDCLNRDN 530
Query: 218 VPLHCVDRHPNQQHVVATGGQDGMLSIWDVRQGTMPVSLLKAHEAEMWEVHFHPSNPEHL 277
C + +V GG+ L+IWD+ T + A + +
Sbjct: 531 YIRSCKLLPDGRTLIV--GGEASTLTIWDLASPTPRIKAELTSSAPACYALAISPDAKVC 588
Query: 278 FTCSEDGSLWHWDASTDVPEKSSLFHQGGRSSTFLSH 314
F+C DG++ WD + H G S +SH
Sbjct: 589 FSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISH 625
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,135,288
Number of Sequences: 37866
Number of extensions: 732612
Number of successful extensions: 2466
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 168
Number of HSP's that attempted gapping in prelim test: 2008
Number of HSP's gapped (non-prelim): 547
length of query: 380
length of database: 18,247,518
effective HSP length: 104
effective length of query: 276
effective length of database: 14,309,454
effective search space: 3949409304
effective search space used: 3949409304
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.