Search of human proteins with 38570121

Search of human proteins with 38570121

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38570121 ring finger protein 184 isoform 1 [Homo sapiens]
         (577 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38570121 ring finger protein 184 isoform 1 [Homo sapiens]         1169   0.0  
gi|224028284 ring finger protein 184 isoform 2 [Homo sapiens]        1012   0.0  
gi|153792110 HEG homolog 1 [Homo sapiens]                              43   7e-04
gi|210147600 tripartite motif-containing 64 [Homo sapiens]             42   0.001
gi|169202375 PREDICTED: tripartite motif-containing protein 64B-...    42   0.001
gi|91982772 mucin 17 [Homo sapiens]                                    42   0.001
gi|83367077 mucin 16 [Homo sapiens]                                    41   0.003
gi|239755486 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|239755484 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|239750044 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|239750042 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|239744355 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|239744353 PREDICTED: tripartite motif-containing protein 64C-...    41   0.003
gi|49472835 bridging integrator 2 [Homo sapiens]                       39   0.013
gi|4557841 recombination activating gene 1 [Homo sapiens]              38   0.022
gi|31982906 cingulin-like 1 [Homo sapiens]                             37   0.049
gi|40806200 metallothionein-like 5, testis-specific isoform a [H...    37   0.049
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]     36   0.084
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]     36   0.084
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]     36   0.084
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]       36   0.084
gi|24025688 ligand of numb-protein X 2 [Homo sapiens]                  36   0.11 
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    35   0.25 
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e...    35   0.25 
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    35   0.25 
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ...    35   0.25 
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ...    35   0.25 
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ...    35   0.25 
gi|151301154 mucin 6, gastric [Homo sapiens]                           35   0.25 
gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]       33   0.55 

>gi|38570121 ring finger protein 184 isoform 1 [Homo sapiens]
          Length = 577

 Score = 1169 bits (3024), Expect = 0.0
 Identities = 577/577 (100%), Positives = 577/577 (100%)

Query: 1   MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS 60
           MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS
Sbjct: 1   MNPVNATALYISASRLVLNYDPGDPKAFTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNS 60

Query: 61  TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII 120
           TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII
Sbjct: 61  TCQHYVCKTCKGKKMMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDII 120

Query: 121 EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES 180
           EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES
Sbjct: 121 EAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSES 180

Query: 181 TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD 240
           TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD
Sbjct: 181 TLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD 240

Query: 241 TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN 300
           TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN
Sbjct: 241 TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSN 300

Query: 301 GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI 360
           GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI
Sbjct: 301 GPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTI 360

Query: 361 IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH 420
           IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH
Sbjct: 361 IRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSH 420

Query: 421 SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR 480
           SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR
Sbjct: 421 SKTKPGILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQR 480

Query: 481 CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS 540
           CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS
Sbjct: 481 CPCYSNRKACLDCICRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNAS 540

Query: 541 TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC 577
           TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC
Sbjct: 541 TSTSVINVTGSPVTTFLAASTHDDKSLDEAIDMRFDC 577


>gi|224028284 ring finger protein 184 isoform 2 [Homo sapiens]
          Length = 503

 Score = 1012 bits (2616), Expect = 0.0
 Identities = 503/503 (100%), Positives = 503/503 (100%)

Query: 75  MMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLN 134
           MMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLN
Sbjct: 1   MMMKPSCSWCKDYEQFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLN 60

Query: 135 DGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGL 194
           DGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGL
Sbjct: 61  DGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGL 120

Query: 195 PTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDIC 254
           PTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDIC
Sbjct: 121 PTYNGLSIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDIC 180

Query: 255 SFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHN 314
           SFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHN
Sbjct: 181 SFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHN 240

Query: 315 VFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTV 374
           VFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTV
Sbjct: 241 VFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTV 300

Query: 375 KRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAV 434
           KRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAV
Sbjct: 301 KRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAV 360

Query: 435 KEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCI 494
           KEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCI
Sbjct: 361 KEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCI 420

Query: 495 CRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVT 554
           CRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVT
Sbjct: 421 CRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVT 480

Query: 555 TFLAASTHDDKSLDEAIDMRFDC 577
           TFLAASTHDDKSLDEAIDMRFDC
Sbjct: 481 TFLAASTHDDKSLDEAIDMRFDC 503


>gi|153792110 HEG homolog 1 [Homo sapiens]
          Length = 1381

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 45/155 (29%), Positives = 64/155 (41%), Gaps = 17/155 (10%)

Query: 299 SNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPIS 358
           S+GP L L S S SH++F S  P+      T A+  + K     S   S S    PLP+S
Sbjct: 671 SSGPPLPLPSVSQSHHLFSSILPS------TRASVHLLKSTSDASTPWSSSP--SPLPVS 722

Query: 359 TIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKK 418
                 T   SAP++V + +         +P    TP  S      T  M   H   +  
Sbjct: 723 L-----TTSTSAPLSVSQTTLPQSSSTPVLPRARETPVTSFQTSTMTSFMTMLHSSQTAD 777

Query: 419 SHSKTKPGILKKDKAVKE-KIPSHHFMPGSPTKTV 452
             S++ P    ++K + E K PS   +P   TK V
Sbjct: 778 LKSQSTP---HQEKVITESKSPSLVSLPTESTKAV 809


>gi|210147600 tripartite motif-containing 64 [Homo sapiens]
          Length = 449

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+      C H  C+ C      +G+  M  PSC    +  
Sbjct: 6   LQVFQNELICCICVNYFIDPV---TIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL      ++LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVVL-------KKL------SSLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|169202375 PREDICTED: tripartite motif-containing protein
           64B-like [Homo sapiens]
          Length = 449

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+      C H  C+ C      +G+  M  PSC    +  
Sbjct: 6   LQVFQNELICCICVNYFIDPV---TIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL      ++LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNLVL-------KKL------SSLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 87/449 (19%), Positives = 165/449 (36%), Gaps = 41/449 (9%)

Query: 146  PSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRF 205
            P  +S    L+ +P+ S S   T    S SP      SIAI S+   G      + +   
Sbjct: 1466 PVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI-STPSEGSTALTSIPVSTT 1524

Query: 206  GINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDS 265
             +        +T     +  + T   + S P   D        T +   ++SE   P  S
Sbjct: 1525 TVASSEINSLSTTPAVTSTPVTTYSQASSSPTTAD-------GTSMQTSTYSEGSTPLTS 1577

Query: 266  LLLSVEEVLRS-LETVSNTEVCCPN-LQPNLEA---TVSNGPFLQLSSQS----LSHNVF 316
            L +S   V+ S   T+S T +     +  + EA   T + G  + +S+ S    L  ++ 
Sbjct: 1578 LPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSIP 1637

Query: 317  MSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQP----LPISTIIRGPTLGASAPV 372
            +ST+P     + T +T  +   +   + +E  S         +P ST   G T   S  V
Sbjct: 1638 VSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITV 1697

Query: 373  TVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKP------- 425
                 +  ++  ++T P   +TP  + T   S+ +  +     +      T P       
Sbjct: 1698 RTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVS 1757

Query: 426  --GILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRAT--QNPSVLTCRGQRC 481
               +L  + +     P     P + +      P   +G     +T  +  + LT      
Sbjct: 1758 TTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSH 1817

Query: 482  PCYSNRKAC------LDCICRGCQNSYMANGEKKLEAFAVPEKALEQ--TRLT-LGINVT 532
               +N +A       +D       ++ +++     E  ++      +  T LT + ++ T
Sbjct: 1818 TLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTT 1877

Query: 533  SIAVRNASTSTSVINVTGSPVTTFLAAST 561
            ++A    +T ++   VT +PVTT+   S+
Sbjct: 1878 TVASSETNTLSTTPAVTSTPVTTYAQVSS 1906



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 80/448 (17%), Positives = 154/448 (34%), Gaps = 44/448 (9%)

Query: 149  SSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAI-----GSSVINGLPTYNGLSID 203
            SS    L+ +P+ ++   TT  +AS SP +    SI       G++ +  +P    L + 
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174

Query: 204  RFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPG 263
                 +      +T  V +   + T   + S PP  +  +    + G      +  +   
Sbjct: 1175 SEANTL------STTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTS-MPVR 1227

Query: 264  DSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMS----- 318
             + + S E    S   V  +     + + +   T + G  L  S+ S    +  S     
Sbjct: 1228 HTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVST 1287

Query: 319  ---TSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVK 375
               TSP    L  T    K   +      S     +   +P ST   G T   S PV   
Sbjct: 1288 TLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTT 1347

Query: 376  RESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKP---------G 426
              +  ++  ++T P   +TP  + T   S+ +  +     +      T P          
Sbjct: 1348 LVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTP 1407

Query: 427  ILKKDKAVKEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRG---QRCPC 483
            ++  + +     P     PG+ +      P   +G     +T +      +       P 
Sbjct: 1408 VVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPV 1467

Query: 484  YSNRKACLD---------CICRGCQNSYMANGEKKLEAFAVPEKALEQTRLT-LGINVTS 533
             ++  + L           +     +S     E    A + P +    T LT + ++ T+
Sbjct: 1468 ANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEG--STALTSIPVSTTT 1525

Query: 534  IAVRNASTSTSVINVTGSPVTTFLAAST 561
            +A    ++ ++   VT +PVTT+  AS+
Sbjct: 1526 VASSEINSLSTTPAVTSTPVTTYSQASS 1553



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 58/274 (21%), Positives = 104/274 (37%), Gaps = 22/274 (8%)

Query: 146  PSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRF 205
            P  SS    L+ +P+ +++  TT  +AS SP +   + + I S+   G      + +   
Sbjct: 2821 PVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPI-STASEGSTLLTSIPVSTT 2879

Query: 206  GINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDS 265
             +        +T  V  ++ + T     S P   +        T + I + SE   P  S
Sbjct: 2880 PVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAE-------GTSMPISTPSEVSTPLTS 2932

Query: 266  LLLSVEEVLRS-LETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQ--------SL 311
            +L+S   V  S   T+S T V        + + +   T + G  + +S+         S+
Sbjct: 2933 ILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSM 2992

Query: 312  SHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAP 371
            S +     S     LS T A           + S   + +   +PIST   G T   S P
Sbjct: 2993 SVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIP 3052

Query: 372  VTVKRESKISLQPIATVPNGGTTPKISKTVLLST 405
            V+    +      ++T P    +P ++ T + S+
Sbjct: 3053 VSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSS 3086



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 64/314 (20%), Positives = 116/314 (36%), Gaps = 54/314 (17%)

Query: 142  ETEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIA-IGSSVINGLPTYNGL 200
            +T  P  +S    L+ +    TS PT+ P    +P++   +S   + SS +N L T    
Sbjct: 3366 DTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLST---T 3422

Query: 201  SIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSD----------SLPPVCDTVATDLCSTG 250
             +D   +   S E S++  +     + T   S+          S  PV  + A+ L +T 
Sbjct: 3423 PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTP 3482

Query: 251  IDICSFSEDIKPGDSLLLSVEEVLRSLET------------VSNTEVCCPNLQPNLEATV 298
            +D  +      P +S   + E       T            VS T V            V
Sbjct: 3483 VDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPV 3542

Query: 299  SNGPFLQLSSQSLSH----------------------NVFMSTSPALHGLSCTAATPKIA 336
             +  F+  SSQ+ S                        + +S++      + T +TP + 
Sbjct: 3543 DSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVD 3602

Query: 337  KLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQ-----PIATVPNG 391
            +     + ++S+S    P  I+  +  P+   S P+T+   S  S+        +T+P  
Sbjct: 3603 RSTPVTTSTQSNSTPTPPEVITLPMSTPS-EVSTPLTIMPVSTTSVTISEAGTASTLPVD 3661

Query: 392  GTTPKISKTVLLST 405
             +TP I+ T + S+
Sbjct: 3662 TSTPVITSTQVSSS 3675



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 54/264 (20%), Positives = 95/264 (35%), Gaps = 12/264 (4%)

Query: 146 PSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLP-TYNGLSIDR 204
           P  SS    L+ +P+ S ++ TT  +AS SP +    S+   +      P T   +S   
Sbjct: 463 PVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMP 522

Query: 205 FGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGD 264
              +  S   +  +D    V   +E  S S  P   ++ T   S G    +   ++    
Sbjct: 523 VASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT---NMPVST 579

Query: 265 SLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQS--------LSHNVF 316
            L++S E    S     +      + + +  +T + G  +  S+ S        +S +  
Sbjct: 580 RLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTT 639

Query: 317 MSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKR 376
           +  S     LS T             + S S + +   +P ST   G T   S PV    
Sbjct: 640 LVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTL 699

Query: 377 ESKISLQPIATVPNGGTTPKISKT 400
            +      ++T P   +TP  + T
Sbjct: 700 VASSEASTLSTTPVDTSTPVTTST 723



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 60/269 (22%), Positives = 97/269 (36%), Gaps = 23/269 (8%)

Query: 146  PSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRF 205
            P  SS    L+ +P  +++  TT  +AS SP +     I I S+   G      + +   
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPI-STPSEGSTPLTSIPVSTT 3056

Query: 206  GINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDS 265
             + IP     +T  V +   + T     S P   +        T + I ++SE   P   
Sbjct: 3057 PVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAE-------GTSMPISTYSEGSTPLTG 3109

Query: 266  LLLSVEEVLRS-LETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQSLSHN--VFM 317
            + +S   V  S + T+S T V        + + +   T S G  +  S+ S       +M
Sbjct: 3110 VPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYM 3169

Query: 318  STSPAL------HGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAP 371
              S  L        LS T             + S + +E    +P ST   G T   S P
Sbjct: 3170 PVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTS-IPTSTPSEGMTPLTSVP 3228

Query: 372  VTVKRESKISLQPIATVPNGGTTPKISKT 400
            V+    +      ++T P    TP  + T
Sbjct: 3229 VSNTPVASSEASILSTTPVDSNTPLTTST 3257



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 57/261 (21%), Positives = 101/261 (38%), Gaps = 25/261 (9%)

Query: 155  LTHSPLPSTSEPTTDPQASLSPMSE-STLSIAIGSSVINGLPTYNGLSIDRFGINIPSPE 213
            L+ +P+ S ++ T   +AS S  +E S+++I+  S    G P    + +    +  P   
Sbjct: 2064 LSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSE---GSPLLTSIPLSTTPVASPEAS 2120

Query: 214  HSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEV 273
              +T  V +   + T     S P     + T+   T +   ++S+   P  S+ +S   V
Sbjct: 2121 TLSTTPVDSNSPVITSTEVSSSP-----IPTE--GTSMQTSTYSDRRTPLTSMPVSTTVV 2173

Query: 274  LRS-LETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQSLSHNVF----MSTSPAL 323
              S + T+S T V        + +     T S G  +  S+ S     F    +ST P +
Sbjct: 2174 ASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVV 2233

Query: 324  HG----LSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESK 379
                  LS T             + S   + +   +P ST+  G T   S PV+    + 
Sbjct: 2234 TSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVAN 2293

Query: 380  ISLQPIATVPNGGTTPKISKT 400
              +  ++T P    TP  + T
Sbjct: 2294 SEVSTLSTTPVDSNTPFTTST 2314



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 53/271 (19%), Positives = 103/271 (38%), Gaps = 23/271 (8%)

Query: 149  SSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGS-----SVINGLPTYNGLSID 203
            SS    L+ +P+ +++  TT  + S SP +    SI   +     + + G+P    L + 
Sbjct: 1999 SSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVS 2058

Query: 204  RFGINIPSPEHSNTIDVCNTVDIKTEDLSD------SLPPVCDTVATDLCSTGIDICSFS 257
              G  + +    +   V N+ +  +   ++      S P     + T +  +   + S  
Sbjct: 2059 SEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVAS-- 2116

Query: 258  EDIKPGDSLLLSVEEVLRSLETVSNTEVCC---PNLQPNLEATVSNGPFLQLSSQSLSHN 314
                  ++  LS   V  +   +++TEV     P    +++ +  +     L+S  +S  
Sbjct: 2117 -----PEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTT 2171

Query: 315  VFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTV 374
            V  S+  A+  LS T         N   +RS   + +   +P ST   G T   S PV+ 
Sbjct: 2172 VVASS--AISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVST 2229

Query: 375  KRESKISLQPIATVPNGGTTPKISKTVLLST 405
                      ++  P   +TP  + T   S+
Sbjct: 2230 MPVVTSEASTLSATPVDTSTPVTTSTEATSS 2260



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 58/266 (21%), Positives = 101/266 (37%), Gaps = 24/266 (9%)

Query: 155  LTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEH 214
            L+ +P+ S +  TT  +AS  P +    S+   +S     P      + R  ++      
Sbjct: 2299 LSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTP------LTRMPVSTTMVAS 2352

Query: 215  SNTIDVCNT-VDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEV 273
              T  +  T  D  T   + S      T A D   T +   ++SE   P  S+ +S   V
Sbjct: 2353 FETSTLSTTPADTSTPVTTYSQAGSSPTTADD---TSMPTSTYSEGSTPLTSVPVSTMPV 2409

Query: 274  LRS-LETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQSLSHNVF----MSTSPAL 323
            + S   T S T V        + + +   T + G  +  S  S          +ST+P +
Sbjct: 2410 VSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVV 2469

Query: 324  HGLSCTAATPKIAKLNRKRSRSESDSEKVQP----LPISTIIRGPTLGASAPVTVKRESK 379
               + T +T  +       + +E+ S         +PIST   G TL  S PV+    + 
Sbjct: 2470 SSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVAS 2529

Query: 380  ISLQPIATVPNGGTTPKISKTVLLST 405
                 ++T P    +P ++ T + S+
Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEISSS 2555



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 63/264 (23%), Positives = 102/264 (38%), Gaps = 30/264 (11%)

Query: 149  SSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGIN 208
            SS T  L+ +P  +++  TT  QAS SP       IA G+S+     +     +     +
Sbjct: 3295 SSETSTLSTTPADTSTPVTTYSQASSSP------PIADGTSMPTSTYSEGSTPLTNMSFS 3348

Query: 209  IPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVA----TDLCSTGIDICSFSEDIKPGD 264
              +P  S+     +T  + T     S P    T A    T    T I   S SE   P  
Sbjct: 3349 T-TPVVSSEASTLSTTPVDT-----STPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLA 3402

Query: 265  SLLLSVEEVLRS-LETVSNTEVCCPNL-----QPNLEATVSNGPFLQLSSQSLSHNVF-- 316
            S+ +S   V+ S + T+S T V    L     + +   T++ G  L  S+ S        
Sbjct: 3403 SMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSI 3462

Query: 317  --MSTSPALHGLSCTAATPKIAKLNRKRSRSESDSE----KVQPLPISTIIRGPTLGASA 370
              +ST+P     + T +T  +       + S ++S     +V  +P ST   G T   + 
Sbjct: 3463 MPLSTTPVASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNM 3522

Query: 371  PVTVKRESKISLQPIATVPNGGTT 394
            PV+    +      ++T P    T
Sbjct: 3523 PVSTTPVASSEASTLSTTPVDSNT 3546



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 58/280 (20%), Positives = 103/280 (36%), Gaps = 37/280 (13%)

Query: 146  PSDSSFTLCLTHSPL---PSTSEPTTDPQASLSPMSESTLSIAIGSS--VINGLPTYNGL 200
            P+D+S T   T+S     P+T++ T+ P ++ S  S    S+ + +   V +   T++  
Sbjct: 2362 PADTS-TPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTT 2420

Query: 201  SIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSD----------SLPPVCDTVATDLCSTG 250
             +D       S E S++        I T   S+          S  PV  + A  L +T 
Sbjct: 2421 PVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTP 2480

Query: 251  IDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQS 310
            +D  +         S   + E+++  + T S       ++       VS  P     + +
Sbjct: 2481 VDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIP------VSTTPVASPEAST 2534

Query: 311  LSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASA 370
            LS     S SP +     +               S + S +   +P ST   G T   S 
Sbjct: 2535 LSTTPVDSNSPVVTSTEIS---------------SSATSAEGTSMPTSTYSEGSTPLRSM 2579

Query: 371  PVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKK 410
            PV+ K  +      ++T P   + P  + T   S+ +  K
Sbjct: 2580 PVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK 2619



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 62/312 (19%), Positives = 116/312 (37%), Gaps = 19/312 (6%)

Query: 110 ITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKPSD-----SSFTLCLTHSPLPSTS 164
           +T +T    +    + +S + + L++GS     T  P       SS     +  P+ S +
Sbjct: 365 VTTSTEPSSLPTTAEATSMLTSTLSEGST--PLTNMPVSTILVASSEASTTSTIPVDSKT 422

Query: 165 EPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNTIDVCNTV 224
             TT  +AS SP +    SIA  S+   G      + +    +      + +T  V +  
Sbjct: 423 FVTTASEASSSPTTAEDTSIAT-STPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSKT 481

Query: 225 DIKTEDLSDSLPPVCD--TVATDLCSTG-IDICSFSEDIKP---GDSLLLSVEEVLRSLE 278
            + T   + S PP  +  ++ T   S G   + S S    P    ++  LS   V  S  
Sbjct: 482 QVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTP 541

Query: 279 TVSNTEVCCPNLQPNLEATVSNGPF---LQLSSQSLSHNVFMSTSPALHGLSCTAATPKI 335
             +++E    +  P   +  ++ P      L++  +S  + +S+  +    S T A    
Sbjct: 542 VTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEAST--TSTTPADSNT 599

Query: 336 AKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTP 395
                  + S S + +   +P ST     T   S  V+    +      ++T P    TP
Sbjct: 600 FVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTP 659

Query: 396 KISKTVLLSTKS 407
             + T   S+ +
Sbjct: 660 VTTSTEATSSST 671



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 56/267 (20%), Positives = 96/267 (35%), Gaps = 24/267 (8%)

Query: 149 SSFTLCLTHSPLPSTSEPTTDPQASLSPM-----SESTLSIAIGSSVINGLPTYNGLSID 203
           SS    L+ +P+ S +  TT  +A+ S       S  T +   GS+ +  +P    L   
Sbjct: 643 SSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTL--- 699

Query: 204 RFGINIPSPEHS--NTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIK 261
                + S E S  +T  V  +  + T   + S P   D  +    ST  +  +    + 
Sbjct: 700 -----VASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT-STPSEGSTPLTSMP 753

Query: 262 PGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMS--- 318
              +LL S E    S   +  +     + + +   T + G  + +S+ S    +  S   
Sbjct: 754 VSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPV 813

Query: 319 -----TSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVT 373
                TSP    LS T               S     +   +P ST   G T   S PV+
Sbjct: 814 SITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS 873

Query: 374 VKRESKISLQPIATVPNGGTTPKISKT 400
               +  ++  ++T P   +TP  + T
Sbjct: 874 TTLVATSAISTLSTTPVDTSTPVTNST 900



 Score = 32.7 bits (73), Expect = 0.93
 Identities = 55/269 (20%), Positives = 100/269 (37%), Gaps = 20/269 (7%)

Query: 145  KPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDR 204
            KP  SS    L+ +P+ ++   TT  + S SP +    S+ I +      P+    S+  
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPIST------PSEVSTSLTS 2637

Query: 205  FGINIPSPEHSNTIDVCNTVDIKTEDL-----SDSLPPVCDTVATDLCSTGIDICSFSED 259
              ++   P  S+     +T  + T  L       S  P     ++   ST  +  +   +
Sbjct: 2638 ILVST-MPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTN 2696

Query: 260  IKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSH----NV 315
            I    +LL + E    S   V  +     + + +   T + G  +++S+ S       ++
Sbjct: 2697 ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSI 2756

Query: 316  FMSTSPALHG----LSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAP 371
             +ST P        +S TA    I       + S   + +V  +P ST     T   S P
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMP 2816

Query: 372  VTVKRESKISLQPIATVPNGGTTPKISKT 400
            V     +      ++T P   +TP  + T
Sbjct: 2817 VNHTPVASSEAGTLSTTPVDTSTPVTTST 2845



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 58/288 (20%), Positives = 110/288 (38%), Gaps = 28/288 (9%)

Query: 143 TEKPSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSI 202
           T  PS+ S  L  T+ P+ +    +++   + +  ++S   +   S   +   T  G S+
Sbjct: 562 TSTPSEGSTPL--TNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSM 619

Query: 203 -----DRFGINIPSPEHSNTIDVCNTVD-IKTEDLSDSLPPVCDTVATDLCSTG----ID 252
                   G  I S   S T+   +    + T  +  + P    T AT   +T     + 
Sbjct: 620 PTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMP 679

Query: 253 ICSFSEDIKPGDSLLLSVEEVLRS-LETVSNTEV-----CCPNLQPNLEATVSNGPFLQL 306
             +++E   P  S+ ++   V  S   T+S T V        + + +   T ++G  +  
Sbjct: 680 TSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPT 739

Query: 307 SSQSLSHNVFMSTSPALHGL--SCTAATPKIAKLNRKRSRSESDSEKVQP-------LPI 357
           S+ S   +  +++ P    L  S  A+T     L+     + S      P       +PI
Sbjct: 740 STPS-EGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPI 798

Query: 358 STIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLST 405
           ST   G  L  S PV++   +      ++T P    +P  + T + S+
Sbjct: 799 STPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 59/292 (20%), Positives = 104/292 (35%), Gaps = 22/292 (7%)

Query: 146  PSDSSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRF 205
            P   S    L+ +P+ + +  TT  +AS SP +    S+ I +      P    +S+   
Sbjct: 2939 PVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPL-TSMSVSTM 2997

Query: 206  GINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDS 265
             +        +      +  + T   + S P   +        TGI I + SE   P  S
Sbjct: 2998 PVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE-------GTGIPISTPSEGSTPLTS 3050

Query: 266  LLLSVEEV-LRSLETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQSLSHN----V 315
            + +S   V +    T+S T V        + + +   T + G  + +S+ S        V
Sbjct: 3051 IPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGV 3110

Query: 316  FMSTSP----ALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAP 371
             +ST+P    A+  LS T             + S   + +   +P ST   G T     P
Sbjct: 3111 PVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMP 3170

Query: 372  VTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKT 423
            V+           ++  P   +TP  + T   S+ + + +    S  S   T
Sbjct: 3171 VSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMT 3222



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 65/303 (21%), Positives = 115/303 (37%), Gaps = 30/303 (9%)

Query: 114  TLARDIIEAVDCSSDILALLNDGSLFCEETEKPSDSSFTLCLTHSPLPSTSEPTTDPQAS 173
            T A  I+  +  +S+   LL   S+    T   S  + TL  T  P+ ++   TT  + S
Sbjct: 2852 TTAEGIVVPISTASEGSTLLT--SIPVSTTPVASSEASTLSTT--PVDTSIPVTTSTEGS 2907

Query: 174  LSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHS--NTIDVCNTVDIKTEDL 231
             SP +    S+ I +      P     SI    + +   E S  +T  V     + T   
Sbjct: 2908 SSPTTAEGTSMPISTPSEVSTPL---TSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAE 2964

Query: 232  SDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRS-LETVSNTEV----- 285
            + S P   +        T + I +  E   P  S+ +S   V  S   T+S T       
Sbjct: 2965 ASSSPTTAE-------GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTP 3017

Query: 286  CCPNLQPNLEATVSNGPFLQLSSQSLSH----NVFMSTSPALHGLSCTAATPKIAKLNRK 341
               + + +   T + G  + +S+ S       ++ +ST+P     + T +T  +   +  
Sbjct: 3018 VTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPV 3077

Query: 342  RSRSESDSEKVQP----LPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKI 397
             + +E  S         +PIST   G T     PV+    +  ++  ++T P   +TP  
Sbjct: 3078 VTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT 3137

Query: 398  SKT 400
            + T
Sbjct: 3138 TST 3140



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 49/247 (19%), Positives = 88/247 (35%), Gaps = 23/247 (9%)

Query: 161  PSTSEPTTDPQAS-------LSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPE 213
            P+TSE T+ P ++       L+ M +ST  +     V +   T +   +D       S E
Sbjct: 906  PTTSEGTSMPTSTPGEGSTPLTSMPDSTTPV-----VSSEARTLSATPVDTSTPVTTSTE 960

Query: 214  HSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLSVEEV 273
             +++        I T   S+   P+  T  +       +  + S      ++ L +  E 
Sbjct: 961  ATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEA 1020

Query: 274  LRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATP 333
                 T   T +  P   P+  +T      +  +  + S    +ST+PA        +TP
Sbjct: 1021 SSPPPTAEGTSM--PTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPA------DTSTP 1072

Query: 334  KIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGT 393
                     S + +D      +P ST   G T   S PV+ +         ++T P   +
Sbjct: 1073 VTTYSQASSSSTTADGTS---MPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTS 1129

Query: 394  TPKISKT 400
             P  + T
Sbjct: 1130 IPVTTST 1136



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 78/427 (18%), Positives = 143/427 (33%), Gaps = 41/427 (9%)

Query: 149  SSFTLCLTHSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGIN 208
            SS    L+ +P+ +++  TT  +AS SP +      A G+S+    P+     +    ++
Sbjct: 702  SSEASTLSTTPVDTSTPVTTSTEASSSPTT------ADGASMPTSTPSEGSTPLTSMPVS 755

Query: 209  IPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLL 268
                  S    +  T    +  ++ S    C    T+   T + I + SE      S+ +
Sbjct: 756  KTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTE--GTSMPISTPSEGSPLLTSIPV 813

Query: 269  SVEEVLR-SLETVSNTEV-----CCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMS---- 318
            S+  V      T+S T V        + + +   T + G  +  S+ S       S    
Sbjct: 814  SITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVS 873

Query: 319  ----TSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTV 374
                 + A+  LS T         N   +RS   + +   +P ST   G T   S P + 
Sbjct: 874  TTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPDST 933

Query: 375  KRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAV 434
                    + ++  P   +TP  + T   S+ +  +     +      T P        +
Sbjct: 934  TPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTP--------L 985

Query: 435  KEKIPSHHFMPGSPTKTVYKKPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLDCI 494
                 SH  +  S   T+   P +           +    T  G   P  +  +      
Sbjct: 986  TSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLT 1045

Query: 495  CRGCQNSYMANGEKKLEAFAVPEKALEQTRLTLGINVTSIAVRNASTSTSVINVTGSPVT 554
                  + +A+ E            L  T       VT+ +   AS+S++  + T  P +
Sbjct: 1046 RMPVSTTMVASSE---------TSTLSTTPADTSTPVTTYS--QASSSSTTADGTSMPTS 1094

Query: 555  TFLAAST 561
            T+   ST
Sbjct: 1095 TYSEGST 1101


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 65/265 (24%), Positives = 108/265 (40%), Gaps = 28/265 (10%)

Query: 152  TLCLTHSPLPSTSEPTTD---PQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGIN 208
            TL    +P P+TS   ++   P  S  P S +T SI +G+   +  P+   + +    + 
Sbjct: 1216 TLVPLDTPSPATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPST--IKLTMASVV 1273

Query: 209  IPSPEHSNTIDVCNT-VDIKTEDLSDSLPPVCDTVATDLCSTGI--DICSFSEDIKPGD- 264
             P      T     T + + T  ++ S     +  A    +TG   D  ++     P D 
Sbjct: 1274 KPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNTGSTWDPTTYITTTDPKDT 1333

Query: 265  -SLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPAL 323
             S  +S    +R+L T  N     P  +    A  S  P +  SS +L       TSPA 
Sbjct: 1334 SSAQVSTPHSVRTLRTTENH----PKTESATPAAYSGSPKIS-SSPNL-------TSPAT 1381

Query: 324  HGLSCTAATPKIAKLNRKRSRSESDSEKVQ--PLPISTII-RGPTLGASAPVTVKRESKI 380
               + T  T    +L+  +   +S   + Q  P P+S +I   PT+G+S   T++  S +
Sbjct: 1382 KAWTITDTTEHSTQLHYTKLAEKSSGFETQSAPGPVSVVIPTSPTIGSS---TLELTSDV 1438

Query: 381  SLQPIATVPNGGTTPKISKTVLLST 405
              +P+   P+  TT  +     LST
Sbjct: 1439 PGEPLVLAPSEQTTITLPMATWLST 1463



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 58/268 (21%), Positives = 97/268 (36%), Gaps = 39/268 (14%)

Query: 158  SPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHSNT 217
            S LP T   T  P  SL   S    +  +G+S     PT +             P  S+T
Sbjct: 6818 STLPKTIHTTPSPMTSLLTPSLVMTTDTLGTSPE---PTTSS-----------PPNLSST 6863

Query: 218  IDVCNTVDIKTEDLSDSLPPVCDTVATDLCST----GIDICSFSEDIKPGDSLLLSVEEV 273
                 T D  T  + +++ P   T AT++ +T    G      ++  K   +  +     
Sbjct: 6864 SHEILTTDEDTTAI-EAMHPSTSTAATNVETTSSGHGSQSSVLADSEKTKATAPMDTTST 6922

Query: 274  LRSLETVSNTEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMSTSPAL------HGLS 327
            +      ++  V     +   E+T S  P L+    S+S N   ST  ++       G +
Sbjct: 6923 MGHTTVSTSMSVSSETTKIKRESTYSLTPGLR--ETSISQNASFSTDTSIVLSEVPTGTT 6980

Query: 328  CTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIR---GPTLGASAPVTVKRESKISLQP 384
               +  ++    R      S S  +  +   T+ R    PT+  SA +T+         P
Sbjct: 6981 AEVSRTEVTSSGRTSIPGPSQSTVLPEISTRTMTRLFASPTMTESAEMTI---------P 7031

Query: 385  IATVPNGGTTPKISKTVLLSTKSMKKSH 412
              T P+G T+         +TKS  K+H
Sbjct: 7032 TQTGPSGSTSQDTLTLDTSTTKSQAKTH 7059



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 64/303 (21%), Positives = 105/303 (34%), Gaps = 53/303 (17%)

Query: 146   PSDSSFTLCLT-----HSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGL 200
             P++SS TL  T     HS L +     T P+A  S    +T+S  I   V+  L T +G 
Sbjct: 11270 PAESSSTLPRTTSRFSHSELDTMPSTVTSPEAESSSAISTTISPGI-PGVLTSLVTSSGR 11328

Query: 201   SIDRFGINIPSPEHSNTID---------VCNTVDIKTEDLSDSLPPVCDTVATD---LCS 248
              I      +P   H +               TV   T + S S P    ++AT      +
Sbjct: 11329 DISATFPTVPESPHESEATASWVTHPAVTSTTVPRTTPNYSHSEPDTTPSIATSPGAEAT 11388

Query: 249   TGIDICSFSEDIK------------------PGDSLLLSVEEVLRSLETVSNTEV--CCP 288
             +     + S D+                   P  +L     E   S  T S T      P
Sbjct: 11389 SDFPTITVSPDVPDMVTSQVTSSGTDTSITIPTLTLSSGEPETTTSFITYSETHTSSAIP 11448

Query: 289   NLQPNLEAT-------VSNGPFLQLSSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRK 341
              L  +  A+       +S+G     +  +L+   +   + A+  +        + +   K
Sbjct: 11449 TLPVSPGASKMLTSLVISSGTDSTTTFPTLTETPYEPETTAIQLIHPAETNTMVPRTTPK 11508

Query: 342   RSRSESDSEKVQPLPISTIIRGPTLGASAPVTV----KRESKISLQPIATVPNGGTTPKI 397
              S S+SD+     LP++    GP   ++   T       +   SL P +      T P +
Sbjct: 11509 FSHSKSDT----TLPVAITSPGPEASSAVSTTTISPDMSDLVTSLVPSSGTDTSTTFPTL 11564

Query: 398   SKT 400
             S+T
Sbjct: 11565 SET 11567


>gi|239755486 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|239755484 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|239750044 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 447

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|239750042 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 450

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|239744355 PREDICTED: tripartite motif-containing protein
           64C-like isoform 1 [Homo sapiens]
          Length = 447

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|239744353 PREDICTED: tripartite motif-containing protein
           64C-like isoform 2 [Homo sapiens]
          Length = 450

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 29/144 (20%)

Query: 35  LPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC------KGKKMMMKPSCSWCKDYE 88
           L  F+  L CC+C +   DP+    + C H  C+ C      +G+  M  P C    +  
Sbjct: 6   LRVFQNELICCICVNYFIDPV---TTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKP 62

Query: 89  QFEENKQLSILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGS--LFCEETEK- 145
            F  N  L       KKL       +LAR        SSD + +L++ +  LFCE  ++ 
Sbjct: 63  NFNTNVAL-------KKL------ASLARQTRPQNINSSDNICVLHEETKELFCEADKRL 109

Query: 146 ----PSDSSFTLCLTHSPLPSTSE 165
                S+S   +  +HSP+   +E
Sbjct: 110 LCGPCSESPEHMAHSHSPIGWAAE 133


>gi|49472835 bridging integrator 2 [Homo sapiens]
          Length = 565

 Score = 38.9 bits (89), Expect = 0.013
 Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 14/141 (9%)

Query: 341 KRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTT------ 394
           K     S SE+ +PLP      GP     +P T + +S+  + P +T P+ G        
Sbjct: 323 KEGSEASSSEEDEPLPACN---GPAQAQPSPTTERAKSQEEVLPSSTTPSPGGALSPSGQ 379

Query: 395 PKISKT-VLLSTKSMKKSHEHGSKKS---HSKTKPGILKKDKAVKEKIPSHHFMPGSPTK 450
           P  S T V+L T++  +  E   K++    +   P      +A     PS   +P SPT 
Sbjct: 380 PSSSATEVVLRTRTASEGSEQPKKRASIQRTSAPPSRPPPPRATASPRPSSGNIPSSPTA 439

Query: 451 TVYKKPQEKKGCKCGRATQNP 471
           +    P   +    G  T +P
Sbjct: 440 SGGGSPTSPR-ASLGTGTASP 459


>gi|4557841 recombination activating gene 1 [Homo sapiens]
          Length = 1043

 Score = 38.1 bits (87), Expect = 0.022
 Identities = 30/110 (27%), Positives = 48/110 (43%), Gaps = 13/110 (11%)

Query: 37  YFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTC--KGKKMMMK--PSCSW-CKDYEQFE 91
           +F +S+SC +C H+L DP+    + C+H  C+ C  +  K+M    PSC + C   +   
Sbjct: 286 HFVKSISCQICEHILADPV---ETNCKHVFCRVCILRCLKVMGSYCPSCRYPCFPTDLES 342

Query: 92  ENKQL-----SILVNCYKKLCEYITQTTLARDIIEAVDCSSDILALLNDG 136
             K       S++V C  K C            I +   S +I   +N G
Sbjct: 343 PVKSFLSVLNSLMVKCPAKECNEEVSLEKYNHHISSHKESKEIFVHINKG 392


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 37.0 bits (84), Expect = 0.049
 Identities = 29/110 (26%), Positives = 46/110 (41%), Gaps = 25/110 (22%)

Query: 316 FMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVK 375
           F     A HG SC  + P    ++ K   +E   E       ST+IR P+LGA +    K
Sbjct: 444 FAKLQGAAHGASCAHSRPPQPNIDGKVLETEGSQE-------STVIRAPSLGAQS----K 492

Query: 376 RESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKP 425
           +E ++                 + T++L  ++   S + G+KK   KT P
Sbjct: 493 KEEEVK--------------TATATLMLQNRATATSPDSGAKKISVKTFP 528


>gi|40806200 metallothionein-like 5, testis-specific isoform a [Homo
           sapiens]
          Length = 508

 Score = 37.0 bits (84), Expect = 0.049
 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 9/56 (16%)

Query: 455 KPQEKKGCKCGRATQNPSVLTCRGQRCPCYSNRKACLD-CICRGCQNSYMANGEKK 509
           KPQ  KGC C R+        C    C CY  +  C   C C GC+N Y  + E+K
Sbjct: 363 KPQHNKGCNCRRS-------GCLKNYCECYEAQIMCSSICKCIGCKN-YEESPERK 410


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 30  EINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMK--PS-CSWCKD 86
           E+  ++   ++ L C +C  L+++P++   + C H  CK C  K +  K  PS C  CK+
Sbjct: 10  EVQNVINAMQKILECPICLELIKEPVS---TKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66

Query: 87  ---YEQFEENKQLSILV-NCYKKLCEYITQTTL 115
                  +E+ + S LV    K +C +   T L
Sbjct: 67  DITKRSLQESTRFSQLVEELLKIICAFQLDTGL 99


>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
          Length = 699

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 30  EINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMK--PS-CSWCKD 86
           E+  ++   ++ L C +C  L+++P++   + C H  CK C  K +  K  PS C  CK+
Sbjct: 10  EVQNVINAMQKILECPICLELIKEPVS---TKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66

Query: 87  ---YEQFEENKQLSILV-NCYKKLCEYITQTTL 115
                  +E+ + S LV    K +C +   T L
Sbjct: 67  DITKRSLQESTRFSQLVEELLKIICAFQLDTGL 99


>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
          Length = 759

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 30  EINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMK--PS-CSWCKD 86
           E+  ++   ++ L C +C  L+++P++   + C H  CK C  K +  K  PS C  CK+
Sbjct: 10  EVQNVINAMQKILECPICLELIKEPVS---TKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66

Query: 87  ---YEQFEENKQLSILV-NCYKKLCEYITQTTL 115
                  +E+ + S LV    K +C +   T L
Sbjct: 67  DITKRSLQESTRFSQLVEELLKIICAFQLDTGL 99


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 36.2 bits (82), Expect = 0.084
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 30  EINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMK--PS-CSWCKD 86
           E+  ++   ++ L C +C  L+++P++   + C H  CK C  K +  K  PS C  CK+
Sbjct: 10  EVQNVINAMQKILECPICLELIKEPVS---TKCDHIFCKFCMLKLLNQKKGPSQCPLCKN 66

Query: 87  ---YEQFEENKQLSILV-NCYKKLCEYITQTTL 115
                  +E+ + S LV    K +C +   T L
Sbjct: 67  DITKRSLQESTRFSQLVEELLKIICAFQLDTGL 99


>gi|24025688 ligand of numb-protein X 2 [Homo sapiens]
          Length = 690

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 36/154 (23%), Positives = 63/154 (40%), Gaps = 7/154 (4%)

Query: 28  FTEINRLLPYFRQSLSCCVCGHLLQDPIAPTNSTCQHYVCKTCKGKKMMMKPSCSWCKDY 87
           +T  N L  Y  +     VC   LQ  + P ++ C H  C  C    +  K  C   +  
Sbjct: 31  WTRENHLYNYQNEVDDDLVCHICLQPLLQPLDTPCGHTFCYKCLRNFLQEKDFCPLDRKR 90

Query: 88  EQFEENKQLSILVN-CYKKLCEYITQTTLARDIIEAVDCSSDILALLNDGSLFCEETEKP 146
             F+  K+ SILV+    KL      +++ +D+++  D  + +       S      E+ 
Sbjct: 91  LHFKLCKKSSILVHKLLDKLLVLCPFSSVCKDVMQRCDLEAHLKNRCPGASHRRVALERR 150

Query: 147 SDSSFTLCLTHSPLPSTSEPT-TDPQASLSPMSE 179
             S      T + + + + PT  DP  +LSP ++
Sbjct: 151 KTSR-----TQAEIENENGPTLLDPAGTLSPEAD 179


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
           [Homo sapiens]
          Length = 1412

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
           [Homo sapiens]
          Length = 1451

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
           [Homo sapiens]
          Length = 1488

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
           [Homo sapiens]
          Length = 1411

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
           [Homo sapiens]
          Length = 1450

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
           [Homo sapiens]
          Length = 958

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 2/87 (2%)

Query: 329 TAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKRESKISLQPIATV 388
           T  +  I+         E+++E  +  P         LGA  P ++K ++K   +     
Sbjct: 76  TRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKT 135

Query: 389 PNGGTTPKISKTV--LLSTKSMKKSHE 413
            N    P   KTV  LLS KS +KS E
Sbjct: 136 GNSMPHPATGKTVANLLSGKSPRKSAE 162


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 34.7 bits (78), Expect = 0.25
 Identities = 68/324 (20%), Positives = 116/324 (35%), Gaps = 48/324 (14%)

Query: 156  THSPLPSTSEPTTDPQASLSPMSESTLSIAIGSSVINGLPTYNGLSIDRFGINIPSPEHS 215
            THSP P+ S P +      +   ++T +    S     LPT+    +  F  ++ +P  +
Sbjct: 1575 THSP-PTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTH----VPPFSTSLVTPS-T 1628

Query: 216  NTIDVCNTVDIKTEDLSDSLPPVCDTVATDLCSTGIDICSFSEDIKPGDSLLLS-VEEVL 274
            +T+       + T     S+P       T L +TG      S    P  +L  S   + L
Sbjct: 1629 HTVITPTHAQMATSASIHSMPTGTIPPPTTLKATG------STHTAPTMTLTTSGTSQAL 1682

Query: 275  RSLETVSN----------------TEVCCPNLQPNLEATVSNGPFLQLSSQSLSHNVFMS 318
             SL T                   T     N+ PN  +T +    +  S  S S + F +
Sbjct: 1683 SSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFST 1742

Query: 319  --TSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQPLPISTIIRGPTLGASAPVTVKR 376
              TS +LH  + +   P++         + + +  + P   ST  R P    ++  + + 
Sbjct: 1743 AKTSTSLHSHTSSTHHPEV---------TSTSTTSITPNHTSTGTRTPVAHTTSATSSRL 1793

Query: 377  ESKISLQ--PIATVPNGGTTPKISKTVLLSTKSMKKSHEHGSKKSHSKTKPGILKKDKAV 434
             +  +    P  T P   T P  + +   +T     SH H +  +H  +    L      
Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853

Query: 435  KEKIPSHHFMPGS------PTKTV 452
               IP+H  M  S      PT T+
Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTI 1877


>gi|239758058 PREDICTED: similar to mucin, partial [Homo sapiens]
          Length = 967

 Score = 33.5 bits (75), Expect = 0.55
 Identities = 68/308 (22%), Positives = 115/308 (37%), Gaps = 38/308 (12%)

Query: 137 SLFCEETEKPSDSSFTLCLTHSPLPSTSEP-------TTDPQASLSPMSESTLSIAIGSS 189
           S+   ET   +  SFT  +T +   S S P       TT+ ++   P+  S+++    +S
Sbjct: 177 SIATSETPSHTVPSFTSLITTTESTSHSNPSLTSAITTTETRSHSPPIFTSSITTIETTS 236

Query: 190 VINGLPTYNGL---------SIDRFGINIPSPEHSNTIDVCNTVDIKTEDLSDSLPPVCD 240
             +  P++  L         S   F  +I + E ++      T  I T +     PP   
Sbjct: 237 --HSTPSFTSLMTTTETTSLSPPAFTFSISTTETNSHSPPSFTSSIATTETPSHSPPSFT 294

Query: 241 TVATDLCSTGIDICSFSEDIKPGDSLLLSVEEVLRSLETVSNTEVCCPNLQPNLEATV-- 298
           ++ T   ST     SF+  I   +S   S      S+ T   T    P+    +  T   
Sbjct: 295 SLITTTESTSHSPLSFTSVITTTESTSHSTPSFTSSIATTETTSHTPPSFTSLITTTETP 354

Query: 299 --SNGPFLQL--SSQSLSHNVFMSTSPALHGLSCTAATPKIAKLNRKRSRSESDSEKVQP 354
             SN  F  L  +++S SH+    TS     ++ T  T     +      +   +    P
Sbjct: 355 SHSNPSFTSLITATESTSHSPPSFTS----AIATTGITSHSTPIFTSLIATTDSTSHSTP 410

Query: 355 LPISTIIRGPTLGASAPVTVKRESKISLQPIATVPNGGTTPKISKTVLLSTKSMKKSHEH 414
              S+I    T+  S P         S    AT     +TP ++ +++ +TKS    H  
Sbjct: 411 SFTSSITSTETISHSTP-------SFSSLITATKTTSHSTPSLT-SLITTTKS--TPHNA 460

Query: 415 GSKKSHSK 422
            S  S+S+
Sbjct: 461 SSFTSYSQ 468


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.129    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,031,930
Number of Sequences: 37866
Number of extensions: 1090347
Number of successful extensions: 4388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 4206
Number of HSP's gapped (non-prelim): 267
length of query: 577
length of database: 18,247,518
effective HSP length: 108
effective length of query: 469
effective length of database: 14,157,990
effective search space: 6640097310
effective search space used: 6640097310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.