Guide to the Human Genome
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Search of human proteins with 124107616

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124107616 claudin 23 [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|124107616 claudin 23 [Homo sapiens]                                610   e-175
gi|11141861 claudin 9 [Homo sapiens]                                   86   3e-17
gi|4502877 claudin 4 [Homo sapiens]                                    76   3e-14
gi|153792768 claudin 6 [Homo sapiens]                                  73   3e-13
gi|153792186 claudin 7 [Homo sapiens]                                  68   8e-12
gi|225703142 claudin 14 [Homo sapiens]                                 67   1e-11
gi|21536294 claudin 14 [Homo sapiens]                                  67   1e-11
gi|225703138 claudin 14 [Homo sapiens]                                 67   1e-11
gi|6912314 claudin 14 [Homo sapiens]                                   67   1e-11
gi|225703140 claudin 14 [Homo sapiens]                                 67   1e-11
gi|10863887 claudin 1 [Homo sapiens]                                   67   2e-11
gi|4502875 claudin 3 [Homo sapiens]                                    66   3e-11
gi|6912316 claudin 17 [Homo sapiens]                                   66   3e-11
gi|7656981 claudin 15 [Homo sapiens]                                   66   3e-11
gi|9966781 claudin 2 [Homo sapiens]                                    64   1e-10
gi|183979973 claudin 19 isoform a [Homo sapiens]                       61   1e-09
gi|183979975 claudin 19 isoform b [Homo sapiens]                       60   2e-09
gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]                 59   4e-09
gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]                 59   5e-09
gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]                 59   5e-09
gi|40788011 claudin 8 [Homo sapiens]                                   57   2e-08
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        56   4e-08
gi|157820127 claudin-like [Homo sapiens]                               54   1e-07
gi|162417973 claudin 22 [Homo sapiens]                                 54   2e-07
gi|195947374 claudin 5 [Homo sapiens]                                  52   5e-07
gi|195947372 claudin 5 [Homo sapiens]                                  52   5e-07
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         52   5e-07
gi|47716519 claudin 20 [Homo sapiens]                                  49   4e-06
gi|33598916 claudin 10 isoform a [Homo sapiens]                        44   2e-04
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    43   4e-04

>gi|124107616 claudin 23 [Homo sapiens]
          Length = 292

 Score =  610 bits (1574), Expect = e-175
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRE 60
           MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRE
Sbjct: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRE 60

Query: 61  RECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVV 120
           RECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVV
Sbjct: 61  RECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQDEPNFVLAGLSGVV 120

Query: 121 LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS 180
           LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS
Sbjct: 121 LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS 180

Query: 181 FAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPK 240
           FAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPK
Sbjct: 181 FAPWCDERCRRRRKGPSAGPRRSSVSTIQVEWPEPDLAPAIKYYSDGQHRPPPAQHRKPK 240

Query: 241 PKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL 292
           PKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL
Sbjct: 241 PKPKVGFPMPRPRPKAYTNSVDVLDGEGWESQDAPSCSTHPCDSSLPCDSDL 292


>gi|11141861 claudin 9 [Homo sapiens]
          Length = 217

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 74/206 (35%), Positives = 101/206 (49%), Gaps = 13/206 (6%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE--LYQGLWDMCREQSSRERECGQT 66
           LGM LA  G L  L     P W+ V  F+   + V   +++GLW  C  QS+ + +C   
Sbjct: 9   LGMTLAVLGWLGTLVSCALPLWK-VTAFIGNSIVVAQVVWEGLWMSCVVQSTGQMQCKVY 67

Query: 67  DQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW---QDE---PNFVLAGLSGVV 120
           D       Q +  ARAL V +L   +LGLL+A  G +C    +DE      VL   +GV+
Sbjct: 68  DSLLALP-QDLQAARALCVIALLLALLGLLVAITGAQCTTCVEDEGAKARIVLT--AGVI 124

Query: 121 LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS 180
           L +AG+L LIPV W  H +      P  A  +  ++  SL LG+  + LL+LGG  L  +
Sbjct: 125 LLLAGILVLIPVCWTAHAIIQDFYNPLVAEALKRELGASLYLGWAAAALLMLGGGLLCCT 184

Query: 181 FAPWCDERCRRRRKGPSAGPRRSSVS 206
             P   ER R  R G S  P RS  S
Sbjct: 185 CPPPQVERPRGPRLGYSI-PSRSGAS 209


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 59/188 (31%), Positives = 92/188 (48%), Gaps = 8/188 (4%)

Query: 6   VMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE--LYQGLWDMCREQSSREREC 63
           +  +G+ LA  G L  +     P WR V  F+   +     +++GLW  C  QS+ + +C
Sbjct: 6   LQVMGIALAVLGWLAVMLCCALPMWR-VTAFIGSNIVTSQTIWEGLWMNCVVQSTGQMQC 64

Query: 64  GQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLG---VRCWQDEPNFVLAGL-SGV 119
              D       Q +  ARAL++ S+    LG+LL+ +G     C +DE       + +GV
Sbjct: 65  KVYDSLLALP-QDLQAARALVIISIIVAALGVLLSVVGGKCTNCLEDESAKAKTMIVAGV 123

Query: 120 VLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLAL 179
           V  +AGL+ ++PVSW  H +      P  AS    ++  SL +G+  S LLLLGG  L  
Sbjct: 124 VFLLAGLMVIVPVSWTAHNIIQDFYNPLVASGQKREMGASLYVGWAASGLLLLGGGLLCC 183

Query: 180 SFAPWCDE 187
           +  P  D+
Sbjct: 184 NCPPRTDK 191


>gi|153792768 claudin 6 [Homo sapiens]
          Length = 220

 Score = 73.2 bits (178), Expect = 3e-13
 Identities = 57/180 (31%), Positives = 85/180 (47%), Gaps = 8/180 (4%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE--LYQGLWDMCREQSS 58
           M +  +  LG+VL   G +  L     P W+ V  F+   + V   +++GLW  C  QS+
Sbjct: 1   MASAGMQILGVVLTLLGWVNGLVSCALPMWK-VTAFIGNSIVVAQVVWEGLWMSCVVQST 59

Query: 59  RERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW----QDEPNFVLA 114
            + +C   D       Q +  ARAL V +L   + GLL+   G +C     + +    L 
Sbjct: 60  GQMQCKVYDSLLALP-QDLQAARALCVIALLVALFGLLVYLAGAKCTTCVEEKDSKARLV 118

Query: 115 GLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
             SG+V  ++G+L LIPV W  H +      P  A     ++  SL LG+  S LLLLGG
Sbjct: 119 LTSGIVFVISGVLTLIPVCWTAHAIIRDFYNPLVAEAQKRELGASLYLGWAASGLLLLGG 178


>gi|153792186 claudin 7 [Homo sapiens]
          Length = 211

 Score = 68.2 bits (165), Expect = 8e-12
 Identities = 49/180 (27%), Positives = 84/180 (46%), Gaps = 11/180 (6%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE-LYQGLWDMCREQSSRERECGQTD 67
           LG  +A  G +  +  T  P W++     +  +  + +Y+GLW  C  QS+    C   D
Sbjct: 9   LGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYD 68

Query: 68  QWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-------DEPNFVLAGLSGVV 120
                 A  +   RALMV SL    L + +A++G++C +        +    + G  G++
Sbjct: 69  SVLALSAA-LQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGG--GII 125

Query: 121 LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS 180
             VAGL  L+  SWY H +      P   + +  +   ++ +G+ GS L++LGG  L+ S
Sbjct: 126 FIVAGLAALVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCS 185


>gi|225703142 claudin 14 [Homo sapiens]
          Length = 239

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 13/212 (6%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGF-LNQPVDVELYQGLWDMCREQSSR 59
           M +  V  LG +L+  G++  L  T+ P WR       N    V   +GLW  C   S+ 
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 60  ERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ----DEPNFVLAG 115
             +C Q  +      Q +  ARALMV S   + +    A +G++C +           A 
Sbjct: 61  IYQC-QIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAI 119

Query: 116 LSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGF 175
           L G +  +AGLL ++ VSW  + +      P   S +  ++  +L LG++ S L L+GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 176 SLALSFAPWCDERCRRRRKGPSAGPRRSSVST 207
            L LS    C +    R   P   P R++ +T
Sbjct: 180 LLCLS----CQDEAPYR---PYQAPPRATTTT 204


>gi|21536294 claudin 14 [Homo sapiens]
          Length = 239

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 13/212 (6%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGF-LNQPVDVELYQGLWDMCREQSSR 59
           M +  V  LG +L+  G++  L  T+ P WR       N    V   +GLW  C   S+ 
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 60  ERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ----DEPNFVLAG 115
             +C Q  +      Q +  ARALMV S   + +    A +G++C +           A 
Sbjct: 61  IYQC-QIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAI 119

Query: 116 LSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGF 175
           L G +  +AGLL ++ VSW  + +      P   S +  ++  +L LG++ S L L+GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 176 SLALSFAPWCDERCRRRRKGPSAGPRRSSVST 207
            L LS    C +    R   P   P R++ +T
Sbjct: 180 LLCLS----CQDEAPYR---PYQAPPRATTTT 204


>gi|225703138 claudin 14 [Homo sapiens]
          Length = 239

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 13/212 (6%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGF-LNQPVDVELYQGLWDMCREQSSR 59
           M +  V  LG +L+  G++  L  T+ P WR       N    V   +GLW  C   S+ 
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 60  ERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ----DEPNFVLAG 115
             +C Q  +      Q +  ARALMV S   + +    A +G++C +           A 
Sbjct: 61  IYQC-QIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAI 119

Query: 116 LSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGF 175
           L G +  +AGLL ++ VSW  + +      P   S +  ++  +L LG++ S L L+GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 176 SLALSFAPWCDERCRRRRKGPSAGPRRSSVST 207
            L LS    C +    R   P   P R++ +T
Sbjct: 180 LLCLS----CQDEAPYR---PYQAPPRATTTT 204


>gi|6912314 claudin 14 [Homo sapiens]
          Length = 239

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 13/212 (6%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGF-LNQPVDVELYQGLWDMCREQSSR 59
           M +  V  LG +L+  G++  L  T+ P WR       N    V   +GLW  C   S+ 
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 60  ERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ----DEPNFVLAG 115
             +C Q  +      Q +  ARALMV S   + +    A +G++C +           A 
Sbjct: 61  IYQC-QIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAI 119

Query: 116 LSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGF 175
           L G +  +AGLL ++ VSW  + +      P   S +  ++  +L LG++ S L L+GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 176 SLALSFAPWCDERCRRRRKGPSAGPRRSSVST 207
            L LS    C +    R   P   P R++ +T
Sbjct: 180 LLCLS----CQDEAPYR---PYQAPPRATTTT 204


>gi|225703140 claudin 14 [Homo sapiens]
          Length = 239

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 60/212 (28%), Positives = 94/212 (44%), Gaps = 13/212 (6%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGF-LNQPVDVELYQGLWDMCREQSSR 59
           M +  V  LG +L+  G++  L  T+ P WR       N    V   +GLW  C   S+ 
Sbjct: 1   MASTAVQLLGFLLSFLGMVGTLITTILPHWRRTAHVGTNILTAVSYLKGLWMECVWHSTG 60

Query: 60  ERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ----DEPNFVLAG 115
             +C Q  +      Q +  ARALMV S   + +    A +G++C +           A 
Sbjct: 61  IYQC-QIYRSLLALPQDLQAARALMVISCLLSGIACACAVIGMKCTRCAKGTPAKTTFAI 119

Query: 116 LSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGF 175
           L G +  +AGLL ++ VSW  + +      P   S +  ++  +L LG++ S L L+GG 
Sbjct: 120 LGGTLFILAGLLCMVAVSWTTNDVVQNFYNPLLPSGMKFEIGQALYLGFISSSLSLIGGT 179

Query: 176 SLALSFAPWCDERCRRRRKGPSAGPRRSSVST 207
            L LS    C +    R   P   P R++ +T
Sbjct: 180 LLCLS----CQDEAPYR---PYQAPPRATTTT 204


>gi|10863887 claudin 1 [Homo sapiens]
          Length = 211

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 51/182 (28%), Positives = 87/182 (47%), Gaps = 15/182 (8%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE-LYQGLWDMCREQSSRERECGQTD 67
           LG +LA  G +  +  T  P WR+     +  V  + +Y+GLW  C  QS+ + +C   D
Sbjct: 9   LGFILAFLGWIGAIVSTALPQWRIYSYAGDNIVTAQAMYEGLWMSCVSQSTGQIQCKVFD 68

Query: 68  QWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-----DEPNFVLAGLSGVVLF 122
                 +  +   RALMV  +   V+ + +A++G++C +     +     +A + G +  
Sbjct: 69  SLLNLSST-LQATRALMVVGILLGVIAIFVATVGMKCMKCLEDDEVQKMRMAVIGGAIFL 127

Query: 123 VAGLLGLIPVSWYNHFLGDRDV--LPAPASPVTVQVSY--SLVLGYLGSCLLLLGGFSLA 178
           +AGL  L+  +WY    G+R V     P +PV  +  +  +L  G+  + L LLGG  L 
Sbjct: 128 LAGLAILVATAWY----GNRIVQEFYDPMTPVNARYEFGQALFTGWAAASLCLLGGALLC 183

Query: 179 LS 180
            S
Sbjct: 184 CS 185


>gi|4502875 claudin 3 [Homo sapiens]
          Length = 220

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 8/180 (4%)

Query: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPV--DVELYQGLWDMCREQSSRERECGQTD 67
           G  LA  G L  +     P WR V  F+   +     +++GLW  C  QS+ + +C   D
Sbjct: 9   GTALAVLGWLGTIVCCALPMWR-VSAFIGSNIITSQNIWEGLWMNCVVQSTGQMQCKVYD 67

Query: 68  QWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRC----WQDEPNFVLAGLSGVVLFV 123
                  Q +  ARAL+V ++     GLL+A +G +C      D     +  ++GV+  +
Sbjct: 68  SLLALP-QDLQAARALIVVAILLAAFGLLVALVGAQCTNCVQDDTAKAKITIVAGVLFLL 126

Query: 124 AGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSFAP 183
           A LL L+PVSW  + +      P        ++   L +G+  + L LLGG  L  S  P
Sbjct: 127 AALLTLVPVSWSANTIIRDFYNPVVPEAQKREMGAGLYVGWAAAALQLLGGALLCCSCPP 186


>gi|6912316 claudin 17 [Homo sapiens]
          Length = 224

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 58/194 (29%), Positives = 91/194 (46%), Gaps = 17/194 (8%)

Query: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDV--ELYQGLWDMCREQSSRERECGQTD 67
           G+VL   G++  L  TL P WR V  F+   + V   L++GLW  C  Q+    +C    
Sbjct: 10  GLVLGFLGMVGTLATTLLPQWR-VSAFVGSNIIVFERLWEGLWMNCIRQARVRLQCKFYS 68

Query: 68  QWGYFEAQPVL-VARALMVTSLAATVLGLLLASLGVRCWQ-----DEPNFVLAGLSGVVL 121
                   P L  ARALM  ++A +++ LL+   G++  Q     +     L G SGV+ 
Sbjct: 69  S--LLALPPALETARALMCVAVALSLIALLIGICGMKQVQCTGSNERAKAYLLGTSGVLF 126

Query: 122 FVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSF 181
            + G+  LIPVSW  + +      PA       ++  +L LG+  + +L +GG  L   F
Sbjct: 127 ILTGIFVLIPVSWTANIIIRDFYNPAIHIGQKRELGAALFLGWASAAVLFIGG-GLLCGF 185

Query: 182 APWCDERCRRRRKG 195
              C   C R+++G
Sbjct: 186 C--C---CNRKKQG 194


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 60/216 (27%), Positives = 90/216 (41%), Gaps = 26/216 (12%)

Query: 6   VMTLGMVLAPCGLLLNLTGTLAPG--WRLVKGFLNQPVDVELYQGLWDMCREQSSREREC 63
           V T G  +A  GLL+   G   P   WR+     N      +++ LW  C   S     C
Sbjct: 5   VETFGFFMATVGLLM--LGVTLPNSYWRVSTVHGNVITTNTIFENLWFSCATDSLGVYNC 62

Query: 64  GQTDQW----GYFEAQPVLVARALMVTSLAATVLGLLLASLGVRC-----WQDEPNFVLA 114
            +        GY +A      RALM+T++    LGLLL   G+RC      +      LA
Sbjct: 63  WEFPSMLALSGYIQA-----CRALMITAILLGFLGLLLGIAGLRCTNIGGLELSRKAKLA 117

Query: 115 GLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
             +G +  +AG+ G++ +SWY  F   RD           ++  +L LG+  S + +LGG
Sbjct: 118 ATAGALHILAGICGMVAISWY-AFNITRDFFDPLYPGTKYELGPALYLGWSASLISILGG 176

Query: 175 FSLALSFAPWCDERCRRRRKGPSAGPRRSSVSTIQV 210
             L       C   C    + P+A  RR   + + V
Sbjct: 177 LCL-------CSACCCGSDEDPAASARRPYQAPVSV 205


>gi|9966781 claudin 2 [Homo sapiens]
          Length = 230

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 50/180 (27%), Positives = 80/180 (44%), Gaps = 12/180 (6%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPV--DVELYQGLWDMCREQSSRERECGQT 66
           +G +L   GLL  L   L P W+    ++   +   V   +GLW  C   S+   +C   
Sbjct: 9   VGYILGLLGLLGTLVAMLLPSWK-TSSYVGASIVTAVGFSKGLWMECATHSTGITQC--- 64

Query: 67  DQWGYFEAQP--VLVARALMVTSLAATVLGLLLASLGVRCW----QDEPNFVLAGLSGVV 120
           D +      P  +  A+A+MVTS A + L  +++ +G+RC     +      +A   GV 
Sbjct: 65  DIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVF 124

Query: 121 LFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALS 180
             + GLLG IPV+W  H +      P     +  ++  +L LG + S   L+ G  L  S
Sbjct: 125 FILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFS 184


>gi|183979973 claudin 19 isoform a [Homo sapiens]
          Length = 224

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 59/210 (28%), Positives = 94/210 (44%), Gaps = 19/210 (9%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPV--DVELYQGLWDMCREQSSRERECGQT 66
           LG  LA  G +  +  T  P W+    +    +   V LY+GLW  C  QS+ + +C   
Sbjct: 9   LGYFLALGGWVGIIASTALPQWKQ-SSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLY 67

Query: 67  DQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-DEPNFVLAG---LSGVVLF 122
           D     +   +  ARALMV ++    + ++L+ +G++C +  + N +  G   ++G  LF
Sbjct: 68  DSLLALDGH-IQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126

Query: 123 V-AGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSF 181
           + AGL  L  VSWY   +      P+       +   +L +G+  + L +LGG  L  + 
Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCCT- 185

Query: 182 APWCDERCRRR------RKGPSAGPRRSSV 205
              C E  R        R GPSA  R   V
Sbjct: 186 ---CPEPERPNSSPQPYRPGPSAAAREPVV 212


>gi|183979975 claudin 19 isoform b [Homo sapiens]
          Length = 211

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 58/206 (28%), Positives = 93/206 (45%), Gaps = 19/206 (9%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPV--DVELYQGLWDMCREQSSRERECGQT 66
           LG  LA  G +  +  T  P W+    +    +   V LY+GLW  C  QS+ + +C   
Sbjct: 9   LGYFLALGGWVGIIASTALPQWKQ-SSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLY 67

Query: 67  DQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-DEPNFVLAG---LSGVVLF 122
           D     +   +  ARALMV ++    + ++L+ +G++C +  + N +  G   ++G  LF
Sbjct: 68  DSLLALDGH-IQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPIAKGRVAIAGGALF 126

Query: 123 V-AGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFSLALSF 181
           + AGL  L  VSWY   +      P+       +   +L +G+  + L +LGG  L  + 
Sbjct: 127 ILAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAVLGGSFLCCT- 185

Query: 182 APWCDERCRRR------RKGPSAGPR 201
              C E  R        R GPSA  R
Sbjct: 186 ---CPEPERPNSSPQPYRPGPSAAAR 208


>gi|169166402 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)

Query: 6   VMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQ 65
           + ++G++L+  G +L++  T  P W+ +   LN+  +  +  GLW  C  Q     +C  
Sbjct: 9   MQSVGLLLSLLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66

Query: 66  TDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW-----QDEPNFVLAGLSGVV 120
            D +    A+ + V+R LM  S     LGLL++  G+ C      Q +    L  L G++
Sbjct: 67  FDSFLALPAE-LRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125

Query: 121 LFVAGLLGLIPVSWYNH----FLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
            + +G+  L+PVSW  H       D +V   P      +   +L LG+     LLLGG
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENV---PDFVPRWEFGEALFLGWFAGLSLLLGG 180


>gi|169167239 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)

Query: 6   VMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQ 65
           + ++G++L+  G +L++  T  P W+ +   LN+  +  +  GLW  C  Q     +C  
Sbjct: 9   MQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66

Query: 66  TDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW-----QDEPNFVLAGLSGVV 120
            D +    A+ + V+R LM  S     LGLL++  G+ C      Q +    L  L G++
Sbjct: 67  FDSFLALPAE-LRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125

Query: 121 LFVAGLLGLIPVSWYNH----FLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
            + +G+  L+PVSW  H       D +V   P      +   +L LG+     LLLGG
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENV---PDFVPRWEFGEALFLGWFAGLSLLLGG 180


>gi|169166931 PREDICTED: claudin-24-like [Homo sapiens]
          Length = 220

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 50/178 (28%), Positives = 83/178 (46%), Gaps = 15/178 (8%)

Query: 6   VMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQ 65
           + ++G++L+  G +L++  T  P W+ +   LN+  +  +  GLW  C  Q     +C  
Sbjct: 9   MQSVGLLLSFLGWILSIITTYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCKD 66

Query: 66  TDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW-----QDEPNFVLAGLSGVV 120
            D +    A+ + V+R LM  S     LGLL++  G+ C      Q +    L  L G++
Sbjct: 67  FDSFLALPAE-LRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGIL 125

Query: 121 LFVAGLLGLIPVSWYNH----FLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
            + +G+  L+PVSW  H       D +V   P      +   +L LG+     LLLGG
Sbjct: 126 SWASGITALVPVSWVAHKTVQEFWDENV---PDFVPRWEFGEALFLGWFAGLSLLLGG 180


>gi|40788011 claudin 8 [Homo sapiens]
          Length = 225

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 49/197 (24%), Positives = 92/197 (46%), Gaps = 15/197 (7%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDV--ELYQGLWDMCREQSS 58
           M T  +   G+ L   G++  +  T+ P WR V  F+   + V    ++GLW  C  Q++
Sbjct: 1   MATHALEIAGLFLGGVGMVGTVAVTVMPQWR-VSAFIENNIVVFENFWEGLWMNCVRQAN 59

Query: 59  RERECGQTDQWGYFEAQPVL-VARALMVTSLAATVLGLLLASLGVRCWQ-----DEPNFV 112
              +C   D        P L  AR LM  +   + L  ++A LG++C +     ++    
Sbjct: 60  IRMQCKIYDS--LLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAH 117

Query: 113 LAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTV-QVSYSLVLGYLGSCLLL 171
           +   +G++  + G++ LIPVSW  + +  RD   +  +     ++  +L LG+  + +L+
Sbjct: 118 ILLTAGIIFIITGMVVLIPVSWVANAI-IRDFYNSIVNVAQKRELGEALYLGWTTALVLI 176

Query: 172 LGGFSLALSFAPWCDER 188
           +GG      F   C+E+
Sbjct: 177 VGGALFCCVFC--CNEK 191


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 50/192 (26%), Positives = 84/192 (43%), Gaps = 25/192 (13%)

Query: 9   LGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECGQTDQ 68
           LG V++  G+   +  T    W     + N    V  YQGLW  C  +SS   EC     
Sbjct: 9   LGFVVSLIGIAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECR---- 64

Query: 69  WGYFE--AQPVLV--ARALMVTSLAATVLGLLLASLGVRC-----WQDEPNFVLAGLSGV 119
            GYF     P ++   RALM+  +    +GLL++   ++C      +D     +   SG+
Sbjct: 65  -GYFTLLGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGI 123

Query: 120 VLFVAGLLGLIPVSWY------NHFLGDRDVLPAPASPV-TVQVSY----SLVLGYLGSC 168
           +  V+GL  +  VS +      N ++   ++       V TVQ  Y    +L +G++   
Sbjct: 124 MFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAALFVGWVAGG 183

Query: 169 LLLLGGFSLALS 180
           L L+GG  + ++
Sbjct: 184 LTLIGGVMMCIA 195


>gi|157820127 claudin-like [Homo sapiens]
          Length = 229

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 55/184 (29%), Positives = 83/184 (45%), Gaps = 23/184 (12%)

Query: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELY-QGLWDMCREQSSRERECGQTDQ 68
           G++L+  G + +   T+ P W+ +   LN+   +E +  G+W++C ++      C   + 
Sbjct: 13  GLLLSLLGWVCSCVTTILPQWKTLNLELNE---METWIMGIWEVCVDREEVATVCKAFES 69

Query: 69  WGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ-DEPNFVL---AGLSGVVLFV- 123
           +     Q + VAR LMV S    +LGLLL S G  C+Q     +V     GL G  L   
Sbjct: 70  FLSLP-QELQVARILMVASHGLGLLGLLLCSFGSECFQFHRIRWVFKRRLGLLGRTLEAS 128

Query: 124 AGLLGLIPVSWYNH-----FLGDR--DVLPAPASPVTVQVSYSLVLGYLGSCLLLLGGFS 176
           A    L+PVSW  H     F  D   D++P        +   +L LG+     L LGG  
Sbjct: 129 ASATTLLPVSWVAHATIQDFWDDSIPDIIP------RWEFGGALYLGWAAGIFLALGGLL 182

Query: 177 LALS 180
           L  S
Sbjct: 183 LIFS 186


>gi|162417973 claudin 22 [Homo sapiens]
          Length = 220

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/179 (27%), Positives = 78/179 (43%), Gaps = 15/179 (8%)

Query: 5   VVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRERECG 64
           V    G+ L+  G +L+      P W+ +   LN+  +  +  GLW  C  Q     +C 
Sbjct: 8   VAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTM--GLWQTCVIQEEVGMQCK 65

Query: 65  QTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCW-----QDEPNFVLAGLSGV 119
             D +    A+ + V+R LM  S     LGLL++  G+ C      Q +    L  L G+
Sbjct: 66  DFDSFLALPAE-LRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGI 124

Query: 120 VLFVAGLLGLIPVSWYNH----FLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
           + + +G+  L+PVSW  H       D +V   P      +   +L LG+     LLLGG
Sbjct: 125 LSWASGVTALVPVSWVAHKTVQEFWDENV---PDFVPRWEFGEALFLGWFAGLSLLLGG 180


>gi|195947374 claudin 5 [Homo sapiens]
          Length = 303

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 18/171 (10%)

Query: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE--LYQGLWDMCREQSSRERECGQTD 67
           G++LA CGL         P W+ V  FL+  +      ++GLW  C  QS+   +C   D
Sbjct: 105 GLILA-CGL---------PMWQ-VTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYD 153

Query: 68  QWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ---DEPNFVLAGLSGVVLFV- 123
                  + V  ARAL V+++    + L +   G +C       P      L+G VL++ 
Sbjct: 154 SVLALSTE-VQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLF 212

Query: 124 AGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
            GLL L+P+ W+ + +      P+       ++  +L +G+  + LL++GG
Sbjct: 213 CGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263


>gi|195947372 claudin 5 [Homo sapiens]
          Length = 303

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 46/171 (26%), Positives = 79/171 (46%), Gaps = 18/171 (10%)

Query: 10  GMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVE--LYQGLWDMCREQSSRERECGQTD 67
           G++LA CGL         P W+ V  FL+  +      ++GLW  C  QS+   +C   D
Sbjct: 105 GLILA-CGL---------PMWQ-VTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYD 153

Query: 68  QWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRCWQ---DEPNFVLAGLSGVVLFV- 123
                  + V  ARAL V+++    + L +   G +C       P      L+G VL++ 
Sbjct: 154 SVLALSTE-VQAARALTVSAVLLAFVALFVTLAGAQCTTCVAPGPAKARVALTGGVLYLF 212

Query: 124 AGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSYSLVLGYLGSCLLLLGG 174
            GLL L+P+ W+ + +      P+       ++  +L +G+  + LL++GG
Sbjct: 213 CGLLALVPLCWFANIVVREFYDPSVPVSQKYELGAALYIGWAATALLMVGG 263


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 50/200 (25%), Positives = 84/200 (42%), Gaps = 25/200 (12%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELYQGLWDMCREQSSRE 60
           M T     +  +L+  GL   +  T    W     + N    V  Y+GLW  C  QSS  
Sbjct: 1   MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVRQSSGF 60

Query: 61  RECGQTDQWGYFE--AQPVLV--ARALMVTSLAATVLGLLLASLGVRC-----WQDEPNF 111
            EC       YF     P ++   RALM+  +    +GLL++   ++C      +D    
Sbjct: 61  TECRP-----YFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKA 115

Query: 112 VLAGLSGVVLFVAGLLGLIPVSWY------NHFLGDRDVLPAPASPV-TVQVSY----SL 160
            +   SG++  V+GL  +  VS +      N ++   ++       V TVQ  Y    +L
Sbjct: 116 NMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMGGMVQTVQTRYTFGAAL 175

Query: 161 VLGYLGSCLLLLGGFSLALS 180
            +G++   L L+GG  + ++
Sbjct: 176 FVGWVAGGLTLIGGVMMCIA 195


>gi|47716519 claudin 20 [Homo sapiens]
          Length = 219

 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 58/224 (25%), Positives = 95/224 (42%), Gaps = 29/224 (12%)

Query: 1   MRTPVVMTLGMVLAPCGLLLNLTGTLAPGWRLVKGFLNQPVDVELY------QGLWDMCR 54
           M +  +  L  +LA  G+   LT TL P W++     N  VD  +        GLW  C 
Sbjct: 1   MASAGLQLLAFILALSGVSGVLTATLLPNWKV-----NVDVDSNIITAIVQLHGLWMDCT 55

Query: 55  EQSSRERECGQTDQWGYFEAQPVLV--ARALMVTSLAATVLGLLLASLGVRCWQ---DEP 109
             S+    C          + P+ V  ARA MV +   + LG+  +++G++C +   D  
Sbjct: 56  WYSTGMFSCALKHS---ILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRE 112

Query: 110 NFVLAGLSGVVLFV-AGLLGLIPVSWY-NHFLGDRDVLPAPASPVTVQVSYSLVLGYLGS 167
               A  +G V F+ AG+  LI   WY    + +   L  P S    +   ++ +G++ +
Sbjct: 113 TKSHASFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESN-KHEPGGAIYIGFISA 171

Query: 168 CLLLLGGFSLALSFAPWCDERCRRRRKGPSAGPRRSSVSTIQVE 211
            LL + G    + F   C +R    R  P   P +  +S  Q+E
Sbjct: 172 MLLFISG----MIFCTSCIKRNPEARLDP---PTQQPISNTQLE 208


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 35/147 (23%), Positives = 66/147 (44%), Gaps = 16/147 (10%)

Query: 45  LYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVA-RALMVTSLAATVLGLLLASLGVR 103
           +YQGLW  C   +     C     +  F+    + A R LM+ +++    G + A  G++
Sbjct: 43  VYQGLWMNCAGNALGSFHC--RPHFTIFKVAGYIQACRGLMIAAVSLGFFGSIFALFGMK 100

Query: 104 CWQ----DEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSY- 158
           C +    D+    +A L+G+V  ++GL  +   S Y +      +      P+ V+  Y 
Sbjct: 101 CTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYAN-----KITTEFFDPLFVEQKYE 155

Query: 159 ---SLVLGYLGSCLLLLGGFSLALSFA 182
              +L +G+ G+ L ++GG     S +
Sbjct: 156 LGAALFIGWAGASLCIIGGVIFCFSIS 182


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 33/146 (22%)

Query: 45  LYQGLWDMCREQSSRERECGQTDQWGYFEAQPVLVARALMVTSLAATVLGLLLASLGVRC 104
           +YQGLW  C                GY +A      R LM+ +++    G + A  G++C
Sbjct: 43  VYQGLWMNCA---------------GYIQA-----CRGLMIAAVSLGFFGSIFALFGMKC 82

Query: 105 WQ----DEPNFVLAGLSGVVLFVAGLLGLIPVSWYNHFLGDRDVLPAPASPVTVQVSY-- 158
            +    D+    +A L+G+V  ++GL  +   S Y +      +      P+ V+  Y  
Sbjct: 83  TKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYAN-----KITTEFFDPLFVEQKYEL 137

Query: 159 --SLVLGYLGSCLLLLGGFSLALSFA 182
             +L +G+ G+ L ++GG     S +
Sbjct: 138 GAALFIGWAGASLCIIGGVIFCFSIS 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,573,834
Number of Sequences: 37866
Number of extensions: 777179
Number of successful extensions: 3513
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 93
Number of HSP's that attempted gapping in prelim test: 3309
Number of HSP's gapped (non-prelim): 233
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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