Guide to the Human Genome
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Name: POLE4 Sequence: fasta or formatted (117aa) NCBI GI: 38455394
Description:

DNA-directed DNA polymerase epsilon 4

Referenced in:

DNA Polymerases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            22.2         26           6
 C cysteine            1.7          2           2
 D aspartate           6.0          7           1
 E glutamate           8.5         10           3
 F phenylalanine       3.4          4           1
 G glycine             6.8          8           1
 H histidine           0.0          0           0
 I isoleucine          3.4          4           1
 K lysine              4.3          5           1
 L leucine             9.4         11           1
 M methionine          0.9          1           1
 N asparagine          0.9          1           1
 P proline             6.0          7           1
 Q glutamine           5.1          6           2
 R arginine            6.8          8           2
 S serine              3.4          4           1
 T threonine           5.1          6           1
 V valine              5.1          6           1
 W tryptophan          0.0          0           0
 Y tyrosine            0.9          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA-directed DNA polymerase epsilon 4 
NFYC                  0.193   nuclear transcription factor Y, gamma isoform 5 [Ho...
NFYC                  0.193   nuclear transcription factor Y, gamma isoform 1 [Ho...
NFYC                  0.193   nuclear transcription factor Y, gamma isoform 3 [Ho...
NFYC                  0.193   nuclear transcription factor Y, gamma isoform 2 [Hom...
CHRAC1                0.158   chromatin accessibility complex 1 
DRAP1                 0.099   DR1-associated protein 1 
POLE3                 0.054   DNA-directed DNA polymerase epsilon 3 
HIF1AN                0.035   hypoxia-inducible factor 1, alpha subunit inhibitor...
CC2D1A                0.030   coiled-coil and C2 domain containing 1A 
SOX12                 0.030   SRY (sex determining region Y)-box 12 
YRDC                  0.030   ischemia/reperfusion inducible protein 
CDC42BPB              0.030   CDC42-binding protein kinase beta 
TRIM24                0.030   transcriptional intermediary factor 1 alpha isoform ...
TRIM24                0.030   transcriptional intermediary factor 1 alpha isoform ...
KIAA1305              0.025   hypothetical protein LOC57523 
BSN                   0.025   bassoon protein 
MAZ                   0.025   MYC-associated zinc finger protein isoform 2 
MAZ                   0.025   MYC-associated zinc finger protein isoform 1 
MARCKS                0.025   myristoylated alanine-rich protein kinase C substra...
ALPK3                 0.025   alpha-kinase 3 
ARX                   0.020   aristaless related homeobox 
FLG                   0.020   filaggrin 
TRIM28                0.020   tripartite motif-containing 28 protein 
SCARA3                0.020   scavenger receptor class A, member 3 isoform 1 [Homo...
KIAA1409              0.020   hypothetical protein LOC57578 
EID2B                 0.020   EP300 interacting inhibitor of differentiation 2B [H...
LOC391769             0.015   PREDICTED: similar to HIStone family member (his-72...
LOC391769             0.015   PREDICTED: similar to HIStone family member (his-72)...
LOC391769             0.015   PREDICTED: similar to HIStone family member (his-72)...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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