Guide to the Human Genome
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Search of human proteins with 38201625

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
isoform 3 [Homo sapiens]
         (1435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...  2849   0.0  
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...  2849   0.0  
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...  2849   0.0  
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...  2849   0.0  
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...  1214   0.0  
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2...   196   1e-49
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i...   196   1e-49
gi|33386693 poly(A) binding protein interacting protein 1 isofor...    81   8e-15
gi|17511255 poly(A) binding protein interacting protein 1 isofor...    81   8e-15
gi|169212085 PREDICTED: similar to poly(A) binding protein inter...    78   7e-14
gi|239752553 PREDICTED: similar to poly(A) binding protein inter...    78   7e-14
gi|89041275 PREDICTED: similar to poly(A) binding protein intera...    78   7e-14
gi|34452730 poly(A) binding protein interacting protein 1 isofor...    77   9e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni...    76   3e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    75   3e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   1e-12
gi|116284392 mucin 2 precursor [Homo sapiens]                          72   4e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    72   4e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    72   4e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     71   9e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             69   2e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    69   3e-11
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 67   9e-11
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       67   9e-11
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       67   9e-11
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    67   1e-10
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    67   1e-10
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    65   4e-10

>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 2849 bits (7386), Expect = 0.0
 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)

Query: 1    MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
            MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 165  MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 224

Query: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
            QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 225  QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 284

Query: 121  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
            IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 285  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 344

Query: 181  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
            LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 345  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 404

Query: 241  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
            NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 405  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 464

Query: 301  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
            EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 465  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524

Query: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
            EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 525  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 584

Query: 421  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
            ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 585  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 644

Query: 481  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
            NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 645  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 704

Query: 541  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
            QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 705  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 764

Query: 601  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
            RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 765  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 824

Query: 661  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
            LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 825  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 884

Query: 721  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
            EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 885  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 944

Query: 781  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
            DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 945  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 1004

Query: 841  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
            IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 1005 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 1064

Query: 901  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
            DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 1065 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1124

Query: 961  ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
            ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 1125 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1184

Query: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
            SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1185 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1244

Query: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
            KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1245 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1304

Query: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
            LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1305 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1364

Query: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
            PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1365 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1424

Query: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
            TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1425 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1484

Query: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
            AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1485 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1544

Query: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
            FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1545 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)

Query: 95  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 150
           P S  P P+PSP L   + P       PG T   +     + + +TP   R+   P R  
Sbjct: 5   PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57

Query: 151 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205
           P P+  A  +         P        S+    P Q   P +     I    G   S  
Sbjct: 58  P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113

Query: 206 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 253
           + P  +   +   P   P  SP           P    ++   G AP+P  ++  P    
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173

Query: 254 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 297
                   + +P +  K++T  +       + PT P       P A     Q   +   +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233

Query: 298 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 354
           +  +G   A   G    E    E  P   +P P+  S  LE  +   +AV S+P      
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292

Query: 355 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 408
            +++ +E+       G+      E  P    +       S P PESE S     P +A  
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349

Query: 409 TWDSKEDKIHNAENIQPGE 427
              S   +IH    + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
            isoform 2 [Homo sapiens]
          Length = 1512

 Score = 2849 bits (7386), Expect = 0.0
 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)

Query: 1    MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
            MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 78   MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 137

Query: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
            QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 138  QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 197

Query: 121  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
            IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 198  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 257

Query: 181  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
            LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 258  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 317

Query: 241  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
            NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 318  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 377

Query: 301  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
            EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 378  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 437

Query: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
            EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 438  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 497

Query: 421  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
            ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 498  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 557

Query: 481  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
            NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 558  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 617

Query: 541  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
            QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 618  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 677

Query: 601  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
            RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 678  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 737

Query: 661  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
            LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 738  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 797

Query: 721  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
            EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 798  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 857

Query: 781  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
            DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 858  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 917

Query: 841  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
            IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 918  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 977

Query: 901  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
            DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 978  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1037

Query: 961  ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
            ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 1038 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1097

Query: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
            SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1098 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1157

Query: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
            KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1158 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1217

Query: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
            LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1218 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1277

Query: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
            PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1278 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1337

Query: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
            TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1338 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1397

Query: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
            AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1398 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1457

Query: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
            FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1458 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1512


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
            isoform 3 [Homo sapiens]
          Length = 1435

 Score = 2849 bits (7386), Expect = 0.0
 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)

Query: 1    MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
            MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 1    MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60

Query: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
            QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120

Query: 121  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
            IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 121  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180

Query: 181  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
            LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 181  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240

Query: 241  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
            NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 241  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300

Query: 301  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
            EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 301  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360

Query: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
            EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420

Query: 421  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
            ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 421  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480

Query: 481  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
            NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 481  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540

Query: 541  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
            QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 541  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600

Query: 601  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
            RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 601  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660

Query: 661  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
            LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 661  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720

Query: 721  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
            EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 721  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780

Query: 781  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
            DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 781  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840

Query: 841  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
            IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 841  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900

Query: 901  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
            DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 901  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960

Query: 961  ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
            ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 961  ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020

Query: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
            SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080

Query: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
            KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140

Query: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
            LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200

Query: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
            PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260

Query: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
            TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320

Query: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
            AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380

Query: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
            FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 2849 bits (7386), Expect = 0.0
 Identities = 1435/1435 (100%), Positives = 1435/1435 (100%)

Query: 1    MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 60
            MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP
Sbjct: 165  MNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETP 224

Query: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
            QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS
Sbjct: 225  QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 284

Query: 121  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 180
            IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP
Sbjct: 285  IPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSP 344

Query: 181  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
            LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL
Sbjct: 345  LQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 404

Query: 241  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 300
            NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE
Sbjct: 405  NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEE 464

Query: 301  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 360
            EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK
Sbjct: 465  EGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKK 524

Query: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 420
            EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA
Sbjct: 525  EAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNA 584

Query: 421  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 480
            ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA
Sbjct: 585  ENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKA 644

Query: 481  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 540
            NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS
Sbjct: 645  NKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRS 704

Query: 541  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
            QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV
Sbjct: 705  QQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 764

Query: 601  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
            RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA
Sbjct: 765  RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 824

Query: 661  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 720
            LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL
Sbjct: 825  LKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEEL 884

Query: 721  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 780
            EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK
Sbjct: 885  EEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGK 944

Query: 781  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 840
            DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ
Sbjct: 945  DLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQ 1004

Query: 841  IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 900
            IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI
Sbjct: 1005 IHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPI 1064

Query: 901  DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 960
            DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS
Sbjct: 1065 DTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFS 1124

Query: 961  ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1020
            ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR
Sbjct: 1125 ALQQAVPTESTDNRRVVQRSSLSRERGEKAGDRGDRLERSERGGDRGDRLDRARTPATKR 1184

Query: 1021 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1080
            SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK
Sbjct: 1185 SFSKEVEERSRERPSQPEGLRKAASLTEDRDRGRDAVKREAALPPVSPLKAALSEEELEK 1244

Query: 1081 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1140
            KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL
Sbjct: 1245 KSKAIIEEYLHLNDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQL 1304

Query: 1141 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1200
            LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK
Sbjct: 1305 LCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITK 1364

Query: 1201 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1260
            PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY
Sbjct: 1365 PLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEY 1424

Query: 1261 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1320
            TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT
Sbjct: 1425 TLGEESEAPGQRALPSEELNRQLEKLLKEGSSNQRVFDWIEANLSEQQIVSNTLVRALMT 1484

Query: 1321 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1380
            AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM
Sbjct: 1485 AVCYSAIIFETPLRVDVAVLKARAKLLQKYLCDEQKELQALYALQALVVTLEQPPNLLRM 1544

Query: 1381 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
            FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN
Sbjct: 1545 FFDALYDEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1599



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)

Query: 95  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 150
           P S  P P+PSP L   + P       PG T   +     + + +TP   R+   P R  
Sbjct: 5   PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57

Query: 151 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205
           P P+  A  +         P        S+    P Q   P +     I    G   S  
Sbjct: 58  P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113

Query: 206 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 253
           + P  +   +   P   P  SP           P    ++   G AP+P  ++  P    
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173

Query: 254 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 297
                   + +P +  K++T  +       + PT P       P A     Q   +   +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233

Query: 298 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 354
           +  +G   A   G    E    E  P   +P P+  S  LE  +   +AV S+P      
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292

Query: 355 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 408
            +++ +E+       G+      E  P    +       S P PESE S     P +A  
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349

Query: 409 TWDSKEDKIHNAENIQPGE 427
              S   +IH    + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
            isoform 4 [Homo sapiens]
          Length = 1403

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 33   MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 92
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60

Query: 93   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 152
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120

Query: 153  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 212
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180

Query: 213  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 272
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240

Query: 273  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 332
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300

Query: 333  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 392
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360

Query: 393  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 452
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420

Query: 453  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 512
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480

Query: 513  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 572
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540

Query: 573  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 632
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600

Query: 633  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 692
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660

Query: 693  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 752
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720

Query: 753  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 812
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780

Query: 813  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 872
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840

Query: 873  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 932
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900

Query: 933  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 992
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960

Query: 993  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1052
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020

Query: 1053 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1112
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080

Query: 1113 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1172
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140

Query: 1173 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1232
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200

Query: 1233 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1292
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260

Query: 1293 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1352
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320

Query: 1353 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1412
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380

Query: 1413 VALKSVTAFFKWLREAEEESDHN 1435
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
            sapiens]
          Length = 1585

 Score = 1214 bits (3142), Expect = 0.0
 Identities = 756/1533 (49%), Positives = 941/1533 (61%), Gaps = 178/1533 (11%)

Query: 3    QPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGA----------RTASTPTPPQTGGGLE 52
            QPP    KRE+KTIRIRDPNQGGKDITEEIMSG           R  STPTPPQ    L 
Sbjct: 131  QPPPA--KREKKTIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQ---LP 185

Query: 53   PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVL---- 108
             Q    +P V   V      + A +A    +        E +P       SPSPVL    
Sbjct: 186  SQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPKPDPVLKSPSPVLRLVL 239

Query: 109  ------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTPISRETGEPYRL----- 149
                        E  +  ++A L +P    T++++  S   +   S  + +P        
Sbjct: 240  SGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDD 299

Query: 150  -----SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT-------PLASHTVEIHEP 197
                 SP    +  P L      S P+P +E      + P        PL S T  I+E 
Sbjct: 300  RCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEI 359

Query: 198  NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP 257
            NG+  SE L    ES  E+      P    + I      E  L   P+P    ++P + P
Sbjct: 360  NGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLECIPAP----ITPSTVP 412

Query: 258  EEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEEE------EEEGEAGEA 307
                   T   +PP  P   PA A + +SP+     +  +EE+E       E+  E    
Sbjct: 413  SFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNK 472

Query: 308  GEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNK--K 360
             E E++   EE+L  ++     +P+PA            Q+A++VPK  +K K+  +  +
Sbjct: 473  IEVEADGQTEEILDSQNLNSRRSPVPA------------QIAITVPKTWKKPKDRTRTTE 520

Query: 361  EAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPRPEEADETWDSKEDKIH 418
            E +   L+   E   ++ +V        + G  PE + S +  + +  +E  +  E   +
Sbjct: 521  EMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-KVKAVEENGEEAEPVRN 579

Query: 419  NAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASM 463
             AE++  GE                 + +K + WKP + E KK+YDREFLL FQF+ A +
Sbjct: 580  GAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACI 639

Query: 464  QKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPR 521
            QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+FA+ GR T   RG P 
Sbjct: 640  QKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPAFADFGRQTPGGRGVPL 696

Query: 522  GGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADK 581
                         +G RRSQ G R+EPRKII TV + ED+ L KAE AWKPS KR     
Sbjct: 697  -----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKKAENAWKPSQKR----- 739

Query: 582  DRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKA 641
            D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +DTEERLKGVIDL+FEKA
Sbjct: 740  DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVDTEERLKGVIDLVFEKA 799

Query: 642  ISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQ 701
            I EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQKEFEKDK DD+VFEKKQ
Sbjct: 800  IDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQ 859

Query: 702  KEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLK 761
            KE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLKMLTEAIMHDCVVKLLK
Sbjct: 860  KELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLK 919

Query: 762  NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDL 821
            NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+KTSSRIRFMLQDV+DL
Sbjct: 920  NHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKERKTSSRIRFMLQDVIDL 979

Query: 822  RGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPPISRGLP 881
            R  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +KRR          G+ 
Sbjct: 980  RLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--EKRR---------PGVQ 1028

Query: 882  LVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKGSSGGSGAKP 941
             VD+GGWNTV  +K SR +D S+  KITKP +ID   QL       SWGKGSSGG+ A  
Sbjct: 1029 RVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQLGSWGKGSSGGAKASE 1087

Query: 942  SDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VVQRSSLSRERGEK-AGD 992
            +D    A R + S+LNRFSALQ   P+ ST       D+RR +  R S+ RE+ +K    
Sbjct: 1088 TD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPS 1143

Query: 993  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1052
               R     RGG   D LD           ++  EE+ RE     + L     +  +   
Sbjct: 1144 ATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLETVKQLTGGVDVERNSTE 1192

Query: 1053 GRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASP 1108
                  RE+A P +S +    KAALSEEELE+KSK+II+E+LH+ND KEA+QCV+EL + 
Sbjct: 1193 AERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQ 1252

Query: 1109 SLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEID 1168
             LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   +++G  E LELA+DM ID
Sbjct: 1253 GLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAID 1312

Query: 1169 IPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKV 1228
            IPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL EIL LLCK M  KKV
Sbjct: 1313 IPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKV 1372

Query: 1229 GTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAPGQRALPSEELNRQLEK 1285
            G LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA  ++ L +EEL ++LEK
Sbjct: 1373 GALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEALSKKELSAEELYKRLEK 1432

Query: 1286 LLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFE-TPLRVDVAVLKAR 1343
            L+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII + +  RVD AV+K R
Sbjct: 1433 LIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQR 1492

Query: 1344 AKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESS 1402
              +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LYDE+V+ EDAFY WESS
Sbjct: 1493 VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESS 1552

Query: 1403 KDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1435
            KDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1553 KDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
           isoform 2 [Homo sapiens]
          Length = 869

 Score =  196 bits (498), Expect = 1e-49
 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)

Query: 543 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 599
           G R  P+    T   +E +     + A  W P+      D       A+  +  D +FR+
Sbjct: 21  GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80

Query: 600 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 659
           VR ILNKLTP+ F +L  ++  + ++++  LKGVI LI +KA+ EP +S  YA +C  L 
Sbjct: 81  VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139

Query: 660 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 711
           A   P  + P          +  FR+LL+++ Q EFE    + +V++K++  +       
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192

Query: 712 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 765
               L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+  LL+          
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247

Query: 766 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 824
            E LECLC+++ T+G  LD E+AK  MDQYF +M  ++  K+  +RIRF+LQD ++LR  
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307

Query: 825 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 875
           +WVPR+   D GPKTI+QI ++A +++    I         SD    GP  PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359



 Score =  113 bits (282), Expect = 2e-24
 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)

Query: 1064 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1122
            P  +  K   S+EEL K ++ ++ EYL+  +  EAV  V+E+ +P   L   +   +  +
Sbjct: 492  PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551

Query: 1123 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1182
            L+RS   +E    L+  L   G  ++  + Q    +L+    +E+DIP V  YLA+    
Sbjct: 552  LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611

Query: 1183 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1242
             +    V + EL     +PL   G    L L  L  L K    + +  L++++ ++ ++ 
Sbjct: 612  AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666

Query: 1243 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1301
            LPE         +Q  +  L E  E  G   L P  +L ++L K +K   S Q ++ WI+
Sbjct: 667  LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717

Query: 1302 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1346
             N+S +  V    V  LMT+                  S+   +  L  +  +L +   +
Sbjct: 718  DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777

Query: 1347 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1405
            +QK+L D    ++ ALYALQ        P  +L  FF   YD ++++E+AF +W+     
Sbjct: 778  MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836

Query: 1406 AEQQGKGVALKSVTAFFKWLREAEEE 1431
             E  GKG AL  V  +  WL  AEEE
Sbjct: 837  QEFPGKGKALFQVNQWLTWLETAEEE 862


>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
           isoform 1 [Homo sapiens]
          Length = 907

 Score =  196 bits (498), Expect = 1e-49
 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)

Query: 543 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 599
           G R  P+    T   +E +     + A  W P+      D       A+  +  D +FR+
Sbjct: 21  GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80

Query: 600 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 659
           VR ILNKLTP+ F +L  ++  + ++++  LKGVI LI +KA+ EP +S  YA +C  L 
Sbjct: 81  VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139

Query: 660 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 711
           A   P  + P          +  FR+LL+++ Q EFE    + +V++K++  +       
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192

Query: 712 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 765
               L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+  LL+          
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247

Query: 766 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 824
            E LECLC+++ T+G  LD E+AK  MDQYF +M  ++  K+  +RIRF+LQD ++LR  
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307

Query: 825 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 875
           +WVPR+   D GPKTI+QI ++A +++    I         SD    GP  PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359



 Score =  113 bits (282), Expect = 2e-24
 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)

Query: 1064 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1122
            P  +  K   S+EEL K ++ ++ EYL+  +  EAV  V+E+ +P   L   +   +  +
Sbjct: 530  PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589

Query: 1123 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1182
            L+RS   +E    L+  L   G  ++  + Q    +L+    +E+DIP V  YLA+    
Sbjct: 590  LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649

Query: 1183 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1242
             +    V + EL     +PL   G    L L  L  L K    + +  L++++ ++ ++ 
Sbjct: 650  AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704

Query: 1243 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1301
            LPE         +Q  +  L E  E  G   L P  +L ++L K +K   S Q ++ WI+
Sbjct: 705  LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755

Query: 1302 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1346
             N+S +  V    V  LMT+                  S+   +  L  +  +L +   +
Sbjct: 756  DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815

Query: 1347 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1405
            +QK+L D    ++ ALYALQ        P  +L  FF   YD ++++E+AF +W+     
Sbjct: 816  MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874

Query: 1406 AEQQGKGVALKSVTAFFKWLREAEEE 1431
             E  GKG AL  V  +  WL  AEEE
Sbjct: 875  QEFPGKGKALFQVNQWLTWLETAEEE 900


>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
           [Homo sapiens]
          Length = 400

 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)

Query: 537 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 596
           P+++ +    +P+ ++A VLM++ + +N  E      S       + G ED        L
Sbjct: 26  PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79

Query: 597 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 651
              V+  LN LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   
Sbjct: 80  SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139

Query: 652 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 711
           A +C  L      + +      NFR+LLL RC+ E+E                       
Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172

Query: 712 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 759
               +K++  +  ++ R+R    + F+GEL+  L++           + +  + + +  L
Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228

Query: 760 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 816
             N  +++L C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML 
Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288

Query: 817 DVLDLRGSNW 826
            +++LR SNW
Sbjct: 289 KLVELRSSNW 298


>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
           [Homo sapiens]
          Length = 479

 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)

Query: 537 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 596
           P+++ +    +P+ ++A VLM++ + +N  E      S       + G ED        L
Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158

Query: 597 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 651
              V+  LN LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   
Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218

Query: 652 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 711
           A +C  L      + +      NFR+LLL RC+ E+E                       
Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251

Query: 712 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 759
               +K++  +  ++ R+R    + F+GEL+  L++           + +  + + +  L
Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307

Query: 760 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 816
             N  +++L C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML 
Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367

Query: 817 DVLDLRGSNW 826
            +++LR SNW
Sbjct: 368 KLVELRSSNW 377



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%)

Query: 197 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 239
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 32  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91

Query: 240 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 296
                 P + D  P    E    +    +AP  +   +   P   PS  S +  E  E+ 
Sbjct: 92  RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151

Query: 297 EEE 299
            E+
Sbjct: 152 CED 154


>gi|169212085 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 516

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 519 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 569
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173

Query: 570 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 624
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228

Query: 625 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 684
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284

Query: 685 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 743
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317

Query: 744 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 789
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377

Query: 790 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 826
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 197 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 239
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 69  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 128

Query: 240 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 294
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 129 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 186


>gi|239752553 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 457

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 519 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 569
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 56  PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114

Query: 570 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 624
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169

Query: 625 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 684
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225

Query: 685 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 743
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258

Query: 744 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 789
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318

Query: 790 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 826
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 197 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 239
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 10  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 69

Query: 240 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 294
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 70  RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 127


>gi|89041275 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 488

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 519 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 569
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 87  PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145

Query: 570 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 624
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200

Query: 625 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 684
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256

Query: 685 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 743
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289

Query: 744 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 789
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349

Query: 790 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 826
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386



 Score = 30.8 bits (68), Expect = 9.8
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 197 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 239
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 41  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 100

Query: 240 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 294
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 101 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 158


>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
           [Homo sapiens]
          Length = 367

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%)

Query: 547 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 606
           +P+ ++A VLM++ + +N  E      S       + G ED        L   V+  LN 
Sbjct: 3   KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56

Query: 607 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 661
           LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   A +C  L   
Sbjct: 57  LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116

Query: 662 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 721
              + +      NFR+LLL RC+ E+E                           +K++  
Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145

Query: 722 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 769
           +  ++ R+R    + F+GEL+  L++           + +  + + +  L  N  +++L 
Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205

Query: 770 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 826
           C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 103/417 (24%), Positives = 148/417 (35%), Gaps = 84/417 (20%)

Query: 8    APKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVR 67
            +PK    T     P+  G   T     GA T    TPP   GGL    +   P  AV+  
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPP-PKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294

Query: 68   PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 127
            P  +             GP  SP +  P+ P+ TP PSP   PG+ P     + P  T  
Sbjct: 1295 PSPKG------------GPATSPPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVT-- 1339

Query: 128  TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPL 187
                                     P+P   P L      SK  P +  S    + PTP 
Sbjct: 1340 ------------------------PPSPKGTPTLPATTPSSKGGPTTPSSK---EGPTPP 1372

Query: 188  ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACP-SESPVPIAPTAQPEELL--NGAP 244
            A+       P  M P     P  +  P +  P   P S + +P++P   P   +   GA 
Sbjct: 1373 AATPSHKGGP-AMTP-----PSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAA 1426

Query: 245  SPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSAT-PATAPSATSPAQEEEMEEEEEEE 300
            +P   DL+P +      K+  A+ AP   P  PS+    T P+ T P+ +E    ++   
Sbjct: 1427 TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 301  EGEAGEAGEAESEKGGEEL---LPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKEL 357
                 +A    +  G   L   +P     +PA  S   +  A T   +S    ++    L
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLS----KKTPATL 1542

Query: 358  NKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKE 414
              KEA+                    PPA + P P+   +   P P+EA  T  SKE
Sbjct: 1543 APKEAL-------------------IPPAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578



 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 102/412 (24%), Positives = 138/412 (33%), Gaps = 56/412 (13%)

Query: 23   QGGKDI-------TEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGA 75
            QG KD        T     GA T S  TP    G   P     TP V  +  P +     
Sbjct: 844  QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 76   IIADRPGLPGPEHSPSESQ--------PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 127
                 P L     SP +++        P+SPSP  +P+P       P       P     
Sbjct: 904  APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSP 959

Query: 128  TIQMSVEESTPISRETGEPYRLSPE--PTPLAEPILEVEVTLSKPVPE-SEFSSSPLQAP 184
                +   +TP S + G P   SP+  PTP A          + P P+    + SP  AP
Sbjct: 960  KWAPTPPAATPPSPK-GGPATPSPKGAPTPPA---------ATPPSPKGGPATPSPKGAP 1009

Query: 185  TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELL- 240
            TP A   V    P G  P+    P+  S+P  A PP+    P+ +P+P      P   L 
Sbjct: 1010 TPPA---VTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP 1065

Query: 241  --NGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 298
               G P+ P++       P   A    +    P  PS   A  P A +P   +       
Sbjct: 1066 SPKGGPATPSLK----GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP 1121

Query: 299  EEEGEAGEAGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRKIKEL 357
             +      A    S KGG    PP+  P  PA    + +   AT      PK        
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT----PPPKGAPTTPAA 1177

Query: 358  NKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 404
                  G L     +  P  P      P G    P  +G     +  PP P+
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 101/454 (22%), Positives = 157/454 (34%), Gaps = 78/454 (17%)

Query: 28   ITEEIMSGARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPDDRSQGAIIADRP----G 82
            +T     G  T    TP   GG   P +  G TP  A    P  +   A+    P     
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PSHKGGPAMTPPSPKRGPA 1394

Query: 83   LPGPEHSPSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP-- 138
            +P P+  P+     P SP   P+     E  + P+   L+ P  T  +++ +   S P  
Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG 1454

Query: 139  ---ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT---------- 185
                    G+P   +  P    EP    +V  S    ++  + +P+ APT          
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPK 1514

Query: 186  -----------PLASHTVEIHE--PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 232
                       P+A     + +  P  + P E L P   + P     PA P+    P  P
Sbjct: 1515 EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATP 1574

Query: 233  TAQPEE--------LLNGAPSPPAVDLSP-VSEPEEQAKEVTASMAPPTIPS--ATPATA 281
            +++              GAPSP  + + P V+ P  +      ++ PP+     ATPA  
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634

Query: 282  PSATSPAQEEEMEEEEEEEEGE--------AGEAGEAESEKGGEELL-------PPESTP 326
             + TSP       ++                 +A +    K G   L        PESTP
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTP 1694

Query: 327  I---PANLSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGDLLDAFKEAN-PAVPEVE 381
            I   P       + ++AT   +   P  +   K      A   LL   K+++  A  +  
Sbjct: 1695 IITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA 1754

Query: 382  NQPPAGSNPGPESEGS---------GVPPRPEEA 406
            +  P G    PES+ S          V P+PE A
Sbjct: 1755 SHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 36/378 (9%)

Query: 35   GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 94
            GA T    TPP   GG    +    P    +  P  +   A        P P+ + +   
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA------ATPFPKGASTPPA 1037

Query: 95   PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES-TPISRETGEPYRLSPEP 153
             + PSP  SP+    P   P     ++P         S++ + TP +     P      P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 154  TPLAEPILEVEVTLSKPVPESEFSSSPLQ-APTPLASHTVEIHEPNGMVPSEDLEPEVES 212
            +P   P   +    + P P+   ++ P + APT  A+       P G + +    P+   
Sbjct: 1098 SPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATP--PPKGAP 1149

Query: 213  SPELAPPP------ACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEEQAKEV 264
            +   A PP      A P     P  P A P     G   PSP     +P + P       
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---- 1205

Query: 265  TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 324
               +A P+ P   P T P+AT P+ +  +      +      A    S KGG    PP+ 
Sbjct: 1206 KGGLATPS-PKGAP-TTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 325  TPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 383
             P  PA    +L+   AT      P        +      G    +  +  P  P     
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 384  PPAGSNPGPESEGSGVPP 401
             P GS   P  +G+  PP
Sbjct: 1319 SPKGSPGTPPPKGAPTPP 1336



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 90/379 (23%), Positives = 119/379 (31%), Gaps = 61/379 (16%)

Query: 35   GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 94
            GA T    TPP   GG    +    P       P  +         P  P P+ +P+   
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-------PATPSPKGAPTPPA 990

Query: 95   PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 154
             + PSP   P+     G+    AV                  TP           SP+ +
Sbjct: 991  ATPPSPKGGPATPSPKGAPTPPAV------------------TP----------PSPKGS 1022

Query: 155  PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 214
            P A P  +   T     P S    SP   P P  + T     P   +PS    P   S  
Sbjct: 1023 PAATPFPKGASTPPAATPPSP-KGSPAATPLPKGAPTT----PAATLPSPKGGPATPSLK 1077

Query: 215  ELAPPPACPSESPVPIAPTAQPEELLNGAPSPP-AVDLSP---VSEPEEQAKEVTASMAP 270
                PPA    SP     T  P+    GAP PP A   SP   ++ P  +    T +  P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPK----GAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 271  P-------TIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPE 323
            P       T P     T P+AT P+ +  +      +      A    S KGG     P+
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPSPK 1192

Query: 324  STP-IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVEN 382
              P  PA    + +   AT      PK              G L     +  P  P    
Sbjct: 1193 GAPTTPAATPPSPKGGLAT----PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 383  QPPAGSNPGPESEGSGVPP 401
              P G    P  +G+  PP
Sbjct: 1249 PSPKGGPATPPPKGAPTPP 1267



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 94/442 (21%), Positives = 140/442 (31%), Gaps = 49/442 (11%)

Query: 4    PPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGG--GLEPQANG-ETP 60
            P   +PK       +  P+  G         GA T    TPP   G     P   G  T 
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059

Query: 61   QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLS 120
              A +  P        +   P  P       +  P++PSP  +P P       P   + +
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119

Query: 121  IPGDTMTTIQMSVEESTPISRETG--EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 178
             P     T       +TP S + G   P       TP A P          P P+   ++
Sbjct: 1120 PPHKGAPT----TPAATPPSPKGGLATPPPKGAPTTPAATP----------PSPKGGLAT 1165

Query: 179  SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP-----ACPSESPVPIAPT 233
             P +      + T    +     PS    P   ++P   PP      A PS    P  P 
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAP---TTPAATPPSPKGGLATPSPKGAPTTPA 1222

Query: 234  AQPEELLNG--APSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATP---------- 278
            A P     G   PSP     +P + P    K   A+  P   PT P+ATP          
Sbjct: 1223 ATPPSPKGGLATPSPKGAPTTPAATP-PSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281

Query: 279  ----ATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQN 334
                A  P+  +P   +        +      A    S KG     PP+  P P  ++  
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341

Query: 335  LEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAV--PEVENQPPAGSNPGP 392
                  T  A +   +       +K+           +  PA+  P  +  P   S  G 
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401

Query: 393  ESEGSGVPPRPEEADETWDSKE 414
             +  + +P  P++A  T  ++E
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTRE 1423



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 87/364 (23%), Positives = 134/364 (36%), Gaps = 89/364 (24%)

Query: 78  ADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQM--SVEE 135
           AD  G+       + +  ++ SP    +  L P + P      +   T+TT+ +  +  E
Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP------VKEGTLTTLPLVPTASE 706

Query: 136 STPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSP-----------LQ 182
           + P++         SP+ T  PLA  +L  E+  S P P    + +P             
Sbjct: 707 NCPVAP--------SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758

Query: 183 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ----PEE 238
           A  P+AS   E        P+ED      +S +        S SP+ ++ + Q    P +
Sbjct: 759 ALAPVASSPKEC-------PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811

Query: 239 LLNGAPSPPAVDLS-PVSEPE-----------EQAKEVTASMAPPTIPSATPATAPSATS 286
             +  P  P  +LS PVS  E           + +K+  A+   PT PS   A  PSA +
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871

Query: 287 PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPA--NLSQNLEAAAATQVA 344
           P                        S KG    LPP+ TP P+  NL    E       A
Sbjct: 872 PL-----------------------SPKG--VTLPPKETPTPSVVNLPFPKEGP-----A 901

Query: 345 VSVPKRRRKIKELNKKEAVGDLLDAFK--EANPAVPEVENQPPAGSNPGPESEGSGVPPR 402
              PK+   +   +          A K   A+P+ P+    PPA + P P  +G    P 
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSP--KGGPATPS 958

Query: 403 PEEA 406
           P+ A
Sbjct: 959 PKWA 962



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 56/223 (25%), Positives = 78/223 (34%), Gaps = 51/223 (22%)

Query: 53   PQANGETPQVA-----VIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV 107
            P++   TP  A     V+ +P+  S  A             SP  S P +PSP P+  P 
Sbjct: 1765 PESKASTPLTAAAFEKVLPKPESASVSAA-----------PSPPVSLPLAPSPVPTLPPK 1813

Query: 108  LE-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT 166
             +   S P L VL  P   +       +E  P+         + PEP     P   V V 
Sbjct: 1814 QQFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQSVLVN 1861

Query: 167  LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES 226
            +  P       S+ +  PTP A   V  +       S+      ES PEL        E 
Sbjct: 1862 MPTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL--------EE 1903

Query: 227  PVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 269
                  T Q  +L   A     +D  PVS+ ++   E  A  A
Sbjct: 1904 QDSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 104/403 (25%), Positives = 146/403 (36%), Gaps = 69/403 (17%)

Query: 23  QGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPG 82
           QGG+ I           S  +PP+ G         + P    +        G + + +P 
Sbjct: 353 QGGQTIRSVAEQHTPVCSRFSPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPK 407

Query: 83  LPGP---EHSPS-----ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVE 134
            PGP   E  P      + +P   +P     P+L P   P  + LS P            
Sbjct: 408 EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPP---PEESPLSPP-----------P 453

Query: 135 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTV 192
           E +P S    E  RLSP P  L    L   + LS+P+ ES  S  P ++P   P  S   
Sbjct: 454 EESPTSPPP-EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512

Query: 193 EIHEPNGMVPSEDLEPEVESSPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDL 251
              E + + P E+  P       L+PPP A P   P   +P + P E L  +P P A  L
Sbjct: 513 SPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRL 572

Query: 252 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEA 307
           SP   PEE      + M+PP  P  +P + P   S    P +E  +    EE        
Sbjct: 573 SP--PPEE------SPMSPP--PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE 622

Query: 308 GEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLL 367
               S        PPE +P+         +    +  +S P    ++  L     V   L
Sbjct: 623 ASRLSP-------PPEDSPM---------SPPPEESPMSPPPEVSRLSPL----PVVSRL 662

Query: 368 DAFKEANPAVPEVENQP----PAGSNPGPESEGSGVPPRPEEA 406
               E +P  P  E  P    P  S   P  E S   P PE++
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%)

Query: 41  TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 96
           T   P+  G L+ +A    P     V+ + + +  +  + P LP PE S    P E  P+
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458

Query: 97  SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 145
           SP P     SP P   P S  P    LS P +         E       ES+P S     
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518

Query: 146 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 198
           P  LSP       P LE  ++       LS P  ES  S  P + PT        +  P 
Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576

Query: 199 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 256
              P   + P  E SP   PP A     P   +P + P E    +P P A  LSP  E  
Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633

Query: 257 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 314
           P     E +    PP +   +P    S  SP  EE       EE       EA       
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691

Query: 315 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 374
                 PPE +P       +  +       +S+P     +  L ++  +    +     +
Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744

Query: 375 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 405
           P   E    P P   +  P++E   + P+PEE
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 87/304 (28%), Positives = 118/304 (38%), Gaps = 33/304 (10%)

Query: 41  TPTPPQTGGGLEPQANGETPQVAVIVRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSP 98
           +P  P     L      E+P + +   P    RS+G  ++ RP  P     P E   S  
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764

Query: 99  SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP------ISRETGEPYRLSPE 152
           +  P  SP  E   EP L   ++P +   + Q      +P      +S +T EP+ LSP 
Sbjct: 765 AEEPHLSPQPE---EPCLC--AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPV 818

Query: 153 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 212
           P    EP L  +   S   P+SE    P  +P P  SH     E   + P  +  PE   
Sbjct: 819 PE---EPCLSPQPEESHLSPQSE---EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872

Query: 213 ---SPE---LAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTA 266
              +PE   L PPP  PS SP+   P          +P P  + LSP  EP    + +  
Sbjct: 873 QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP 932

Query: 267 SMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 326
              PP +     A AP A SP  E E         G  G++ + ES      L  P S P
Sbjct: 933 DPLPPPLSPIITAAAPPALSPLGELEY------PFGAKGDS-DPESPLAAPILETPISPP 985

Query: 327 IPAN 330
             AN
Sbjct: 986 PEAN 989



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 100/401 (24%), Positives = 142/401 (35%), Gaps = 52/401 (12%)

Query: 41  TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP---------- 90
           +P P ++     P+++  +P     + P + S  +   + P  P PE SP          
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554

Query: 91  ---SESQPSSP-------SPTP-----SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 135
               E  P+SP       SP P     SP P   P S P  A    P    + +    EE
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614

Query: 136 STPISRETGEPYRLSPEP--TPLAEPILEVEVTLSKPVPESEFSSSPLQA---PTPLASH 190
           S P+S    E  RLSP P  +P++ P    E  +S P   S  S  P+ +   P P  S 
Sbjct: 615 S-PLSPPP-EASRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670

Query: 191 TVEIHEPNGMVPSED---LEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 247
                E +   P  +   L P  E SP   PP   P+  P        PE+ L   P   
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--------PEDSLMSLPLEE 722

Query: 248 AVDLSPVSEPEEQAKEVTASMAP-PTIPSATPATAPSATSPAQEEEMEEEEEEEE--GEA 304
           +  L    EP+   +     ++P P  P  +P       SP  EE     + EE      
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782

Query: 305 GEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 364
            E      +  G  L P    P   +LS   E    + V        +  +     ++  
Sbjct: 783 PEEPHLSPQAEGPHLSP---QPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE 839

Query: 365 DLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 405
             L    E +   PE+E +PP    P    E  G  P PEE
Sbjct: 840 PCLSPRPEESHLSPELE-KPPLSPRPEKPPEEPGQCPAPEE 879



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 67/299 (22%), Positives = 104/299 (34%), Gaps = 42/299 (14%)

Query: 5    PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANG-----ET 59
            PQ  P   +    +R P Q      ++ +S   TA   +  Q G G   +A+        
Sbjct: 4082 PQPQPSSLQLQPPLRLPGQ-----QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136

Query: 60   PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSE-PNLAV 118
            P V++  +P   +Q  +   +P L  P  + +  QP      P P PVL+ G   P + +
Sbjct: 4137 PSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQP------PKPGPVLQSGQGLPGVGI 4190

Query: 119  LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPIL-------EVEVTLSKPV 171
            +   G     +Q  + ++  +         LSP+     + +L          V  + P 
Sbjct: 4191 MPTVGQLRAQLQGVLAKNPQLR-------HLSPQQQQQLQALLMQRQLQQSQAVRQTPPY 4243

Query: 172  PESEFSSSPLQAPTPLASHTVEIHEP-NGMVPSEDLEPEVESSPELAPPPACPSESPV-- 228
             E    +SPLQ              P  G +      P  +  P L  PP   S  PV  
Sbjct: 4244 QEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG 4303

Query: 229  PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 287
            P+ PT          PS P     P   P   ++  T +  PPT P       P+   P
Sbjct: 4304 PVHPTP--------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 116/494 (23%), Positives = 158/494 (31%), Gaps = 124/494 (25%)

Query: 7    IAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPT----PPQTGGGLEPQANGETPQV 62
            IA K +R  + +R P Q G       +     A+ PT     P T  GL   A+G     
Sbjct: 2093 IARKTDRPALHLRIPPQPGA------LGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146

Query: 63   AVIVRPDDRSQGAIIADRPGLPG--PEHSPSESQPSSP--------SPT--PSPSPVLEP 110
            A  V   D      +   P +P   P   P    P+ P         PT  P PSP   P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206

Query: 111  GSEPNLAVLS-----IPGDTMTT-----------------------IQMSVEESTPISRE 142
               P L   S      PG+  TT                         ++V ES  +   
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266

Query: 143  TGEPYRLSPEPTPLAEPILEV---EVTLSKP---VPESEFSSSP----------LQAP-- 184
                  LSP P   +   LEV   E+  S P    P   F  SP          L+ P  
Sbjct: 2267 KASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV 2326

Query: 185  -----TPLASHTVEIHEPN-GMVPSED-----LEPEVESSPEL----------APPPACP 223
                 TP AS  VE   P  G+ P E      L P   S P++          A PP  P
Sbjct: 2327 FKAPLTPRASQ-VEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTP 2385

Query: 224  SESPVP------IAPTAQPEELLNGAPSPP---AVDLSPVSEPEEQAKEVTASMAPPTIP 274
               P P      + P + P +  +  P+ P   +   SP++     A+    S   P   
Sbjct: 2386 RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQ 2445

Query: 275  SATPATAPSATSPAQE------EEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES---- 324
            S  P + P +   +++      +    +  E   +AG         GG     P      
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGE 2505

Query: 325  --TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVEN 382
                +P+    N   +  T   V  P   R        +AVG+         P VP+   
Sbjct: 2506 LHAKVPSGQPPNFVRSPGTGAFVGTPSPMR----FTFPQAVGE-----PSLKPPVPQPGL 2556

Query: 383  QPPAGSN----PGP 392
             PP G N    PGP
Sbjct: 2557 PPPHGINSHFGPGP 2570



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 81/343 (23%), Positives = 119/343 (34%), Gaps = 59/343 (17%)

Query: 35   GARTASTPTPPQTGGGLE------PQANGETPQVA--VIVRPDDRS-----QGAIIADRP 81
            GA+  S P  P     LE      P+AN   P+    +I+ P   S        ++   P
Sbjct: 962  GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021

Query: 82   GLPGP--EHS--PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST 137
                P  +HS  P  S PS  SP   P  V  P S P   V+ +  D     +M  E+ +
Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS-PIGKVVGV-SDEAELHEMETEKVS 1079

Query: 138  PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP 197
                   EP   SP P+P+ +    +      P P  +  S   +   PL        +P
Sbjct: 1080 EPECPALEPSATSPLPSPMGD----LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP 1135

Query: 198  NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA------------QPEELLNGAPS 245
                    L  E++ SP L  P      +P+ + P              Q E     AP+
Sbjct: 1136 EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPT 1195

Query: 246  PPAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAPSAT---------SPAQEE- 291
            PP +  S +        +  AS     + P + S  P    S +         SPA++E 
Sbjct: 1196 PPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEG 1255

Query: 292  ----------EMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 324
                      E ++    + G A   G+AE EKG     P  S
Sbjct: 1256 SLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARS 1298



 Score = 38.9 bits (89), Expect = 0.036
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 21/85 (24%)

Query: 217  APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV-TASMAPPTIPS 275
            APPP  PS  P P+AP                   SP S P E   E+ T  +A P +PS
Sbjct: 4908 APPPEEPSPPPSPLAP-------------------SPASPPTEPLVELPTEPLAEPPVPS 4948

Query: 276  ATP-ATAPSATSPAQEEEMEEEEEE 299
              P A++P +  P       EE E+
Sbjct: 4949 PLPLASSPESARPKPRARPPEEGED 4973



 Score = 37.7 bits (86), Expect = 0.080
 Identities = 95/415 (22%), Positives = 137/415 (33%), Gaps = 86/415 (20%)

Query: 34   SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 92
            SG  T STPT P T G    + +G +     + R + D   G +    P L    + P+ 
Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031

Query: 93   SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 137
             Q  P   S            P    +P L+   +   A            Q++ +    
Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091

Query: 138  PISRETGEP---YRLSPEPTPLAEPILEVEVTL------------------------SKP 170
             I+R+T  P    R+ P+P  L  P      T+                        S P
Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP 2151

Query: 171  VPESE---FSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP 227
             P+S    F   P Q P  + S      +P G+ P+  LEP   ++P   PP   P+ +P
Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQ-----DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206

Query: 228  VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 287
                  AQP  L  GA S P        +P E            T P  TP   PS   P
Sbjct: 2207 ------AQPPML--GASSRPG-----AGQPGEF----------HTTPPGTPRHQPSTPDP 2243

Query: 288  AQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSV 347
              +      +     E+   G     K  E LL    +P P   S+        ++  S 
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVG---GGKASEPLL----SPPPFGESRKALEVKKEELGASS 2296

Query: 348  PKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 402
            P             + G  L   +   P V +    P A S   P+S G G+ P+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 67/307 (21%), Positives = 100/307 (32%), Gaps = 59/307 (19%)

Query: 42   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG-AIIADRPGLPGPEHSPSESQPSSPSP 100
            P PP++   L P++    P   V   P  +S   + +  RP L      PS   P   SP
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSP 2447

Query: 101  TPSPSPVLEPGSEPNLAVL------------------------------SIPGDTMTTIQ 130
             P   P   P S    A L                              ++P      + 
Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507

Query: 131  MSVEESTPIS--RETGE-PYRLSPEPTPLAEPILEVEVTLSKPVPE----------SEFS 177
              V    P +  R  G   +  +P P     P    E +L  PVP+          S F 
Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567

Query: 178  SSPLQAPTPLASHTVEI--HEPNG--MVPSEDLEPEVESSPELAPPPACPSESPVPIAPT 233
              P        ++TV      P+G  + PS     E      L PP   P     P AP 
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP-----PPAPD 2622

Query: 234  AQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEM 293
                 L +GA     +  SPV + E+    + +S+A   +P     T     S   + E+
Sbjct: 2623 GSLPYLSHGASQRSGIT-SPVEKREDPGTGMGSSLATAELPG----TQDPGMSGLSQTEL 2677

Query: 294  EEEEEEE 300
            E++ + +
Sbjct: 2678 EKQRQRQ 2684



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%)

Query: 82   GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 141
            G PGP+  P +   + P P   P     PG+     VL                      
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303

Query: 142  ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 201
                P   +P P+   EP                    P Q P+P +    E   P    
Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337

Query: 202  PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 261
            P+    P+ +  P L PPP   S +   +A T   + L    P  P  +L+   +PE+  
Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391

Query: 262  KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 296
                +S+ P  +        P A+  + ++E  EE
Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422



 Score = 34.7 bits (78), Expect = 0.68
 Identities = 102/468 (21%), Positives = 165/468 (35%), Gaps = 87/468 (18%)

Query: 6    QIAPKRERKTIR---IRDPNQGGKDITEEIMSGARTASTPTPPQTGGG------LEPQAN 56
            ++  +R+R+ +R   IR   Q    + +E  + A  A    PP + G        E  + 
Sbjct: 2676 ELEKQRQRQRLRELLIRQQIQRNT-LRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSR 2734

Query: 57   GETP------QVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV--- 107
            G+TP      + +++  P  +  G I+       GP   PS+ + S P P  +PS +   
Sbjct: 2735 GQTPFAGTQDKSSLVGLPPSKLSGPIL-------GPGSFPSDDRLSRPPPPATPSSMDVN 2787

Query: 108  ---LEPGSEPNLAVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSPE----PTP---- 155
               L  GS+        PG   +   Q  + +    +  T   + +S      P P    
Sbjct: 2788 SRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGR 2847

Query: 156  --LAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE-PNGMVPSEDLEPEVES 212
              L  P+  +   L  P         P+  P   A      H    G+ P     P    
Sbjct: 2848 QALGSPLAGISTRLPGP-------GEPVPGPAGPAQFIELRHNVQKGLGPGG--TPFPGQ 2898

Query: 213  SPELAPPPACPSESPVPIAPTAQPEELLNGAP-----SPPAVDLSPVSEPEEQAKEVTAS 267
             P   P     SE P  +AP       ++G P     +PPA +L+    P    K  T  
Sbjct: 2899 GPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958

Query: 268  MAPPTI---PSAT------PATAPSATSPAQEEEMEEE-------EEEEE----GEAGEA 307
                 +   PS+T      P    +   P ++ E++++       E++EE    G   + 
Sbjct: 2959 TGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDEELAHLGLGVDV 3018

Query: 308  GEAESEKGGEELLPPESTPIPANLS-QNLEAAAATQVAVSVPKRR-------RKIKELNK 359
             + + E G  E L      +   L+    +  A T   +    ++       R ++  N+
Sbjct: 3019 AKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANE 3078

Query: 360  KEAVGDLLDAFKEANPAVPEVENQPPA--GSNPGPESEGSGVPPRPEE 405
            K     LL    E  P  PE E  PPA   S P   S    V P+ EE
Sbjct: 3079 KAEREALLRGV-EPGPLGPE-ERPPPAADASEPRLASVLPEVKPKVEE 3124



 Score = 34.3 bits (77), Expect = 0.89
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 14/100 (14%)

Query: 183  APTPLASHTVEIHEPNGMVPSEDLEPEVESSPE---LAPPPACPSESP---VPIAPTAQP 236
            AP P   H+   +  N  V      P  E SP    LAP PA P   P   +P  P A+P
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944

Query: 237  EELLNGAPSPPAVDLSPVS---EPEEQAKEVTASMAPPTI 273
                   PSP  +  SP S   +P  +  E      PP +
Sbjct: 4945 P-----VPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 76/292 (26%), Positives = 112/292 (38%), Gaps = 21/292 (7%)

Query: 5   PQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAV 64
           P ++P     TI    P Q    +         ++    P +T   L P +  +TP  ++
Sbjct: 475 PAVSPLSSPLTIH---PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL-QTPPASL 530

Query: 65  IVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP---SPSPVLEPGSEPNLAVLSI 121
              P +               P  +P    P  P+P P    PSP+  P  E   ++ + 
Sbjct: 531 TTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590

Query: 122 PGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPL 181
           P      +      S P+      P      P P A P L +    + P P +    SPL
Sbjct: 591 PPQAPPALA-----SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 182 QAPTPLASHTVEIH---EPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEE 238
             P+P A + + +H    P    PS  ++     SP  A PP  PS +P   AP +    
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPP-ASPPVSPSATPPSQAPPSLAAP 702

Query: 239 LLNGAPSPPAVD-LSPVSEPEEQAKEVTAS--MAPPTIPSATPATAPSATSP 287
            L   PSPPA   +SP + P  QA    A+  +  P  P A+P  +PSAT P
Sbjct: 703 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 75/252 (29%), Positives = 104/252 (41%), Gaps = 28/252 (11%)

Query: 40  STPTPPQTGGGLEPQANG-ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSP 98
           +TP P        P   G  +P ++ +  P  ++   +    P L  P  SP  S P SP
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL--PPLQAPP-SPPASPPLSP 644

Query: 99  SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAE 158
             TPSP            A  S P         S   S P+S     P   S  P  LA 
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAA 701

Query: 159 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP 218
           P L+V  +     P S  ++ P QAP PLA+  +++       PS    P +  SP   P
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP------PSPPASPPM--SPSATP 753

Query: 219 PPACPSESPVPIAPTAQPEELLNGAPSPPA-VDLSPVSEPEEQAKEVTAS---MAPPTIP 274
           PP  P   P+  AP  Q        PSPPA + +SP+++P  QA    A+    A P+ P
Sbjct: 754 PPRVP---PLLAAPPLQVP------PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 275 SATPATAPSATS 286
           ++ P  AP + S
Sbjct: 805 ASFPGQAPFSPS 816



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 69/251 (27%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 80  RPGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIPGDTMTTIQMS 132
           RP    P+  P +   S P+SP    S SP + P S P     L  LS          +S
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505

Query: 133 VEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPESEFSSSPLQA 183
                P+  ++   P  L   P  L  P LE   +L        S P+      + P  A
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565

Query: 184 PTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVPIAPTAQPEEL 239
           P PL +    +  P    PS    P  ++ P LA PP      P  SP+   P   P  L
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 240 ----LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTASMAPPTIPSA 276
               L   PSPPA   LSP++ P  QA                    V A  +PP  P  
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 277 TPATAPSATSP 287
           +P+  P + +P
Sbjct: 686 SPSATPPSQAP 696



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 64/221 (28%), Positives = 89/221 (40%), Gaps = 27/221 (12%)

Query: 90  PSESQPS--SPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 147
           P E+Q S   PS    P+ +  P  E   ++   P  T +    +    TP       P 
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP---PCPAPC 567

Query: 148 RLSPEPTPLAEPILEVEVTLSKPVPESE--FSSSPLQA-PTPLASHTVEIHEPNGMVPSE 204
            L   P+PL  P  E   +++ P P++    +S PLQ  P+P  S    +  P    P  
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS---PLATPPPQAPPX 624

Query: 205 DLEPEVESSPEL-APPPACPSESPVPIAPTAQPEELLNGA----PSPPA-VDLSPVSEPE 258
              P +++ P   A PP  P  +P P AP A    LL       PSPP     SP + P 
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 259 EQAKEVTASMAPPTI----------PSATPATAPSATSPAQ 289
                   S APP++          P A+P  +PSAT P Q
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 70/305 (22%), Positives = 106/305 (34%), Gaps = 53/305 (17%)

Query: 6   QIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTP---PQTGGGLEPQANGETPQV 62
           ++   R   + R R P +G +         + T  +P     P  GGGL+          
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ---------- 235

Query: 63  AVIVRPDDRS--QGAIIADRPGLPGPEHSPSESQPSSPS-PTPSPSPVLEPGSEPNLAVL 119
               RP  RS    A     P   GP    +   P+ PS P P     L P   P +   
Sbjct: 236 ----RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP---PQVT-- 286

Query: 120 SIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSS 179
             P        +    S+P++  +    +  P P P            + P+P +   S 
Sbjct: 287 --PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP---------DNAATPLPATLPPSP 335

Query: 180 PLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL 239
           PL  P PLA  +         +PS    P  ++ P +  PP     S   I P   P  L
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395

Query: 240 ----LNGAPSPPAVD----LSPVSEPEEQA---------KEVTASMAPPTIPSATPATAP 282
               L   PSP A+      + +  P  QA         ++  AS+  P+ P++TP  +P
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455

Query: 283 SATSP 287
              +P
Sbjct: 456 PLQAP 460



 Score = 44.3 bits (103), Expect = 9e-04
 Identities = 72/300 (24%), Positives = 94/300 (31%), Gaps = 54/300 (18%)

Query: 89   SPSESQPSSPSPTPSP-----------------------SPVLEPGSEPNLAVLSIPGDT 125
            SP  S P SPS TP P                       SP+ +P  +   A+ + P   
Sbjct: 740  SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 126  MTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP- 184
            + +   S     P S     P      P P A P+L   +     VP S  +S  LQAP 
Sbjct: 800  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPR 856

Query: 185  -TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 240
              P       +  P     + P     P    S  L+ P      S    + T+ PEE L
Sbjct: 857  RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-L 911

Query: 241  NGAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEE 292
             G  S P      SP  + E  A    A    P  P A       P   P AT P   + 
Sbjct: 912  RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971

Query: 293  MEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 352
            +    E E  E+        + G          P P        A A    +   PK+ R
Sbjct: 972  LCTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 60/257 (23%), Positives = 92/257 (35%), Gaps = 17/257 (6%)

Query: 40   STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 99
            +TP+PP T     P     +P ++    P   +  +     P  P    SP  +  ++P 
Sbjct: 1436 TTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495

Query: 100  PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP---TPL 156
            PT +PSP       P    ++ P  T TT+  +   S P +  T  P   +P P   TP+
Sbjct: 1496 PTTTPSP-------PTTTPITPPAST-TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547

Query: 157  AEPILEVEV---TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 213
              P     +   T   P P +  +  P   P+P  + T          P     P   ++
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607

Query: 214  PELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 270
                PPP      P   PI P      L     PSPP    +        +   T + +P
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667

Query: 271  PTIPSATPATAPSATSP 287
            P   + TP    + +SP
Sbjct: 1668 PITTTTTPPPTTTPSSP 1684



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 64/246 (26%), Positives = 85/246 (34%), Gaps = 34/246 (13%)

Query: 38   TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 97
            T +T TPP T     P     TP  +    P               P    SP  +  ++
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1571

Query: 98   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 157
            P PT +PSP       P     S P  T TT   +   S P +  T  P   +P P P  
Sbjct: 1572 PPPTTTPSP-------PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTT 1623

Query: 158  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 217
             PI     T + P P +  S  P    TP  + T          P     P    +    
Sbjct: 1624 TPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPS--------PPTTTTPSPPITTTTT 1674

Query: 218  PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT 277
            PPP     SP+   P+  P       PSP     SP++     +   T S  P T+ + +
Sbjct: 1675 PPPTTTPSSPITTTPS--PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 278  PATAPS 283
            P T PS
Sbjct: 1733 PTTTPS 1738



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 65/260 (25%), Positives = 87/260 (33%), Gaps = 19/260 (7%)

Query: 76   IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 135
            I    P    P   P+ +    P+ TPSP P     + P     S P  T TT   +   
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 136  STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 195
            S PIS  T  P   +P P     P        + P P +  +++P    TP    T  I 
Sbjct: 1455 SPPISTTTTPPPTTTPSP-----PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509

Query: 196  EPNGMVPSEDLEPEVESSP----ELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPA 248
             P     +  L P    SP       PPP      P   PI P      L     PSPP 
Sbjct: 1510 PP---ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566

Query: 249  VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 308
               +        +   T + +PPTI + TP   P  T+P+               +    
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPPTTTTTTPPPTTTPSPPTT 1623

Query: 309  EAESEKGGEELLPPESTPIP 328
               +       LPP +TP P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSP 1643



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 20/218 (9%)

Query: 40   STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 99
            +TP+PP T     P     +P       P        I      P    SP  +  ++P 
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITTTTPPPTTTPSPPTTTTTTPP 1613

Query: 100  PTPSPSP-----VLEPGSE---PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 151
            PT +PSP     +  P S    P     S P  T TT   +   S P +     P   + 
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673

Query: 152  EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 211
             P P   P   +  T   P P +   ++P    TP +  T      +   PS        
Sbjct: 1674 TPPPTTTPSSPITTT---PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730

Query: 212  SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 249
             SP   P P   + + +P   T+ P   L   P PP++
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSP---LTTTPLPPSI 1765



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 67/268 (25%), Positives = 95/268 (35%), Gaps = 43/268 (16%)

Query: 38   TASTPTPPQTGGGLEPQANGETP-QVAVIVRPDDRSQGA-------IIADRPGLPGPEHS 89
            T  TPTP  TG     Q    TP      V P     G        I       P P  +
Sbjct: 4067 TTVTPTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122

Query: 90   PSESQPSSP-------SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 142
             +++  ++P       +PTP+P+    P + P     ++   T T        +TPI+  
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTT 4181

Query: 143  TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP 202
            T     ++P PTP          T + P+ E   S+ P ++ TP  S +           
Sbjct: 4182 T----TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS--------- 4228

Query: 203  SEDLEPEVESSPELAP-PPACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEE 259
                 P  ES+  L+  PPA    S  P +    P     G     PP+   SP   P  
Sbjct: 4229 ----SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284

Query: 260  QAKEVTASMAPPTIPSATPATAPSATSP 287
                 T S + PT PS    T  SA +P
Sbjct: 4285 GT--TTGSSSAPT-PSTVQTTTTSAWTP 4309



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 57/214 (26%), Positives = 74/214 (34%), Gaps = 34/214 (15%)

Query: 38   TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 97
            T +T TPP T     P     TP  +    P               P    SP  +  ++
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1650

Query: 98   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 157
            P PT +PSP       P     S P  T TT   +   S+PI+     P      P+P  
Sbjct: 1651 PPPTTTPSP-------PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703

Query: 158  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 217
             P   +  T +   P S  + SP        S T     P   + +  L P   SSP L 
Sbjct: 1704 TPSSPITTTTT---PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT--LPPTTTSSP-LT 1757

Query: 218  PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 251
              P  PS +P    PT  P       P+ P V L
Sbjct: 1758 TTPLPPSITP----PTFSP--FSTTTPTTPCVPL 1785



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 62/280 (22%), Positives = 94/280 (33%), Gaps = 54/280 (19%)

Query: 38   TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 97
            T  TPTP  TG    P  +  T  +A +   +              P PE S  ++  S+
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN--------------PPPESSTPQTSRST 4227

Query: 98   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 157
             SP    + +L             P   MT+       + P +   G  + LSP P+   
Sbjct: 4228 SSPLTESTTLLSTLP---------PAIEMTSTAPPSTPTAPTTTSGG--HTLSPPPSTTT 4276

Query: 158  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 217
             P          P   +   SS    P+ + + T     P    P+    P +  +  L 
Sbjct: 4277 SPP-------GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT---PTPLSTPSIIRTTGLR 4326

Query: 218  PPPA----CPSESPVPIAPTAQPEELLNGAPSPPAV----DLSPVSE------PEEQAKE 263
            P P+    C   +    AP    EE+ NG            LS   E      P   +  
Sbjct: 4327 PYPSSVLICCVLNDTYYAPG---EEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 4383

Query: 264  VTASMAPPTI--PSATPATAPSATSPAQEEEMEEEEEEEE 301
             T S + PT   PS+TP+     T P +  + +   +E E
Sbjct: 4384 PTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENE 4423


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)

Query: 59  TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 118
           +P ++ +  P  ++  A+    P L  P  SP  S P SP  TPSP            A 
Sbjct: 383 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 439

Query: 119 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 178
            S P         S   S P+S     P   S  P  LA P L+V  +     P S  ++
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 496

Query: 179 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 232
            P QAP PLA+  +++ +P    P     P +++ P  +PP + P ++P      +P++P
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 554

Query: 233 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 273
            A P           LL   PSPPA           +P  +       +T ++A  PP  
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614

Query: 274 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 329
           PS +P++  S    A          EE       G     +GG    PP    +    PA
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 669

Query: 330 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 387
             S+      A + A   P            + +  + +    + A PA   ++  P  G
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729

Query: 388 SNPGPESEGSG 398
           ++ G  + G+G
Sbjct: 730 TSGGKAAAGAG 740



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 75/316 (23%), Positives = 108/316 (34%), Gaps = 33/316 (10%)

Query: 5   PQIAPKRERKTIRIRDPNQGGKDIT-EEIMSGARTASTPTPPQTGGGLEPQANGETPQV- 62
           P  +P R   T R     Q G  I+ EE ++  +    P       G     +G TP   
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172

Query: 63  AVIVRPDDRSQGAIIA---------DRPGLPGPEHS---PSESQPSSPSPTPSPSPVLEP 110
           +  +    R+ G  +           RP   GP  S    SE   + PSP     P    
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 111 GSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSK 169
           G + P    LS     +++   S   +    R    P +  P+      P          
Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 170 PVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP-SEDLEPEVESSPELAPPP--ACPSES 226
                  SSSPL  P+P A+   +        P S  L  ++ +   LAPP   A PS  
Sbjct: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352

Query: 227 PVPIAPTAQPEELLNGAPSP---------PAVDLSPVSEPEEQAKE------VTASMAPP 271
            +P  P   P +      SP         P+  LSP++ P  QA        + A  +PP
Sbjct: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412

Query: 272 TIPSATPATAPSATSP 287
             P  +P   PS  +P
Sbjct: 413 ASPPLSPLATPSPQAP 428



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%)

Query: 40  STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 99
           S P  P       P A+   P V+    P  ++  ++ A  P L  P  SP  S P SPS
Sbjct: 441 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 494

Query: 100 PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 149
            TP   +P P       + +P  +   A+ + P   + +   S     P S     P   
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 150 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 204
              P P A P+L   +     VP S  +S  LQAP   P       +  P     + P  
Sbjct: 555 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611

Query: 205 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 262
              P    S  L+ P      S    + T+ PEE L G  S P      SP  + E  A 
Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 666

Query: 263 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 316
              A    P  P A       P   P AT P   + +    E E  E+        + G 
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 725

Query: 317 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 352
                    P P        A A    +   PK+ R
Sbjct: 726 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 752


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)

Query: 59  TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 118
           +P ++ +  P  ++  A+    P L  P  SP  S P SP  TPSP            A 
Sbjct: 344 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 400

Query: 119 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 178
            S P         S   S P+S     P   S  P  LA P L+V  +     P S  ++
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 457

Query: 179 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 232
            P QAP PLA+  +++ +P    P     P +++ P  +PP + P ++P      +P++P
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 515

Query: 233 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 273
            A P           LL   PSPPA           +P  +       +T ++A  PP  
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 274 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 329
           PS +P++  S    A          EE       G     +GG    PP    +    PA
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 630

Query: 330 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 387
             S+      A + A   P            + +  + +    + A PA   ++  P  G
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690

Query: 388 SNPGPESEGSG 398
           ++ G  + G+G
Sbjct: 691 TSGGKAAAGAG 701



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 74/305 (24%), Positives = 107/305 (35%), Gaps = 41/305 (13%)

Query: 5   PQIAPKRERKTIRIRDPNQGGKDIT-EEIMSGARTASTPTPPQTGGGLEPQANGETPQV- 62
           P  +P R   T R     Q G  I+ EE ++  +    P       G     +G TP   
Sbjct: 104 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 163

Query: 63  AVIVRPDDRSQGAIIA---------DRPGLPGPEHS---PSESQPSSPSPTPSPSPVLEP 110
           +  +    R+ G  +           RP   GP  S    SE   + PSP     P    
Sbjct: 164 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 223

Query: 111 GSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSK 169
           G + P    LS     +++   S   +    R    P +  P+      P          
Sbjct: 224 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 283

Query: 170 PVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVP 229
                  SSSPL  P+P A             PS    P +++ P  +PP   PS++   
Sbjct: 284 APALGPLSSSPLATPSPSAP------------PSPSAPPSLQTLP--SPPATPPSQATTS 329

Query: 230 I-APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE------VTASMAPPTIPSATPATAP 282
           + +PT Q        PSPP   LSP++ P  QA        + A  +PP  P  +P   P
Sbjct: 330 LGSPTLQATHSF--LPSPP---LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384

Query: 283 SATSP 287
           S  +P
Sbjct: 385 SPQAP 389



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%)

Query: 40  STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 99
           S P  P       P A+   P V+    P  ++  ++ A  P L  P  SP  S P SPS
Sbjct: 402 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 455

Query: 100 PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 149
            TP   +P P       + +P  +   A+ + P   + +   S     P S     P   
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515

Query: 150 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 204
              P P A P+L   +     VP S  +S  LQAP   P       +  P     + P  
Sbjct: 516 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 205 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 262
              P    S  L+ P      S    + T+ PEE L G  S P      SP  + E  A 
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 627

Query: 263 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 316
              A    P  P A       P   P AT P   + +    E E  E+        + G 
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 686

Query: 317 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 352
                    P P        A A    +   PK+ R
Sbjct: 687 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 713



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 63/264 (23%), Positives = 93/264 (35%), Gaps = 53/264 (20%)

Query: 74  GAIIADRPGLPGPEHSP-----SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT-MT 127
           GA I +     GP  +         + + P+   SP PV  PG        + PG     
Sbjct: 67  GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT---TRPGPLGQK 123

Query: 128 TIQMSVEESTPISRETGEPYRLSPE---------PTP-LAEPILE-------VEVTLSKP 170
            +++S EE+    + T  P R +           PTP    P +         EV L +P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183

Query: 171 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV--------------ESSPEL 216
            P +     P + P    S   E H      P+    P                 ++P  
Sbjct: 184 APSAR-PRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 217 APPPACPSESPVPIAPT--AQP-----EELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 269
           +P  + PS    P AP   +QP     + L     +PP  D +P   P   +   T S +
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 270 PPTIPSATPA----TAPSATSPAQ 289
            P  PSA P+     +P AT P+Q
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQ 325


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 70.9 bits (172), Expect = 9e-12
 Identities = 109/487 (22%), Positives = 187/487 (38%), Gaps = 34/487 (6%)

Query: 245 SPPAVDL-SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 303
           SPPA +  SP  E +   KE   S A    P    A +P+     ++ +   +EE +   
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562

Query: 304 AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAV 363
             ++ E E  K   E+  PE    PA      E A +   A S  K +  +KE  K  A 
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAK-----EEAKSPAEAKSPEKAKSPVKEEAKSPA- 616

Query: 364 GDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENI 423
            +     KE   +  EV++   A S    E++       PE+ +     K      AE  
Sbjct: 617 -EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675

Query: 424 QPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKT 483
            P + K   K++   P   E+ K   +E     +   + +++    P  +   + +  KT
Sbjct: 676 SPEKAKSPVKAEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732

Query: 484 PLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQG 543
           P +   P + +  +     +P  A     TL  + P    P  E  R PA   P +++  
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAK----TLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788

Query: 544 PRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 600
            ++E   P K  A   + ED K  + E   K   K    ++++ +E     K ++  ++ 
Sbjct: 789 VKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE----VKVKEPPKKA 842

Query: 601 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 660
                  TP+  ++  K   +     +E  K  ++   E A+ +P  S   A        
Sbjct: 843 EEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900

Query: 661 LKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD-------EVFEKKQKEMDEAATAEE 712
            KVPT EK     V  ++    + + E  K + DD       +  EKK+   ++  T EE
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960

Query: 713 RGRLKEE 719
           + +  EE
Sbjct: 961 KAKKPEE 967



 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 98/452 (21%), Positives = 168/452 (37%), Gaps = 45/452 (9%)

Query: 4    PPQI-APKRE--RKTIRIRDPNQGGKDITEEIMSGARTAS---TPTPPQTGGGLEPQANG 57
            PP+  +P++E  +    ++ P +      EE  S A   S     +P +       +A  
Sbjct: 561  PPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKS 620

Query: 58   ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLA 117
               + A         + A    +     PE + S  +  + SP  + SPV      P  A
Sbjct: 621  PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680

Query: 118  VLSIPGDTMTTIQMSVEESTPISRETGEPYRL-------SPEPTPLAEPILEVEVTLSKP 170
               +  +  +      +  +P+  E   P +        +  P     P+ E   T  K 
Sbjct: 681  KSPVKAEAKSP----EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736

Query: 171  V-PESEFSSSPLQAPTPLASHTVEIHEPNGMVPS-EDLEPEVESSPELAPPPA-----CP 223
              P  E + SP +A +P  + T+++  P    P+ E+     +  PE A  P       P
Sbjct: 737  KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSP 796

Query: 224  SESPVPIAPTAQ-PEELL---NGAPSPPAVDLSP----VSEPEEQAKEVTASMAPPTIPS 275
             ++  P+   A+ PE+ +       SP   +  P    V EP ++A+E  A   P T   
Sbjct: 797  EKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856

Query: 276  ATP----ATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANL 331
                   A    A  P  EE+ E   E+ +    EA + E+E   +   P +  P    +
Sbjct: 857  KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV 916

Query: 332  SQNLEAAAATQVAVSVP---KRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGS 388
             ++ +    T+VA   P   K +   K   KKEA  +  D  KE     PE + +  A +
Sbjct: 917  KEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDT-KEEKAKKPEEKPKTEAKA 975

Query: 389  NPGPESEGSGVPPRPE----EADETWDSKEDK 416
                ++  S  P +P+    E   + D K+ K
Sbjct: 976  KEDDKTL-SKEPSKPKAEKAEKSSSTDQKDSK 1006



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 106/469 (22%), Positives = 180/469 (38%), Gaps = 47/469 (10%)

Query: 6   QIAPKRERKTIRIRDPNQGGKDITEEIMSGA-RTASTPTPPQTGGGLEPQANG-----ET 59
           ++  K E++T+ + +  +  + +TEE+     + A      +  GG E +A G     ++
Sbjct: 445 KVVEKSEKETVIVEEQTEETQ-VTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKS 503

Query: 60  PQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP----SPVLEPGSEPN 115
           P       P+  ++  +  +    P    SP + +  SP+   SP    SP  E    P 
Sbjct: 504 PPAEEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562

Query: 116 LAVLSIPGDTMTTIQMSVEE--STPISRETGEPYRL-SPE--PTPLAEPILEVEVTLSKP 170
            A      +  +  ++   E   +P   E   P    SPE   +P+ E   E +      
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE---EAKSPAEAK 619

Query: 171 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA-----CPSE 225
            P  E + SP +  +P  + +    E      ++  E E   SPE A  P       P +
Sbjct: 620 SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK 679

Query: 226 SPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP-EEQAKEVTASMAPPTIPSATPATAPSA 284
           +  P+   A+  E         A        P +E+AK    + +P    + TP     A
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTP---EKA 736

Query: 285 TSPAQEEEMEEEEEEEEGEAG----EAGEAESEKGGEELLPPESTPIPANLSQNLEAAAA 340
            SP +EE    E+ +   +A     ++ EA++    E   P +  P  A  S   E   +
Sbjct: 737 KSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAK-SPVKEEVKS 795

Query: 341 TQVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 398
            + A S  K   K   KE+ KKE V          +P   E + Q      P  ++E   
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEV---------KSPVKEEEKPQEVKVKEPPKKAEEEK 846

Query: 399 VPPRPEEADETWDSKEDKIHNAENIQPG-EQKYEYKSDQWKPLNLEEKK 446
            P  P + +E  DSK+++    E  +P  E+K E   ++ K   +E KK
Sbjct: 847 APATP-KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKK 894



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 85/367 (23%), Positives = 134/367 (36%), Gaps = 28/367 (7%)

Query: 93  SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 152
           S P      PS S  ++  SE  + V+         ++   EE+      T E  + + E
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480

Query: 153 PTPLAEPILEVEVTL-----SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 207
                E   E E        +K  P  E +S   +A +P+        E       E   
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540

Query: 208 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-SPPAVDLSPVSEPEE---QAKE 263
           P    SPE A  PA       P A + + EE  + A    P    SP  E  +   +AK 
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600

Query: 264 VTASMAPPTIPSATPATAPS-----ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 318
              + +P    + +PA A S     A SPA+ +  E+ +   + EA    +A+S +  EE
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEE 659

Query: 319 LLPPESTPIPANLSQNLEAAAATQV---AVSVPKRRRKIKELNK-----KEAVGDLLDAF 370
              PE    P          A + V   A S  K +  +KE  K     K  V +   + 
Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 719

Query: 371 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKY 430
           ++A   V E    P    +P  E   S     PE+A     +K   + + E   P +++ 
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKS-----PEKAKSPEKAKTLDVKSPEAKTPAKEEA 774

Query: 431 EYKSDQW 437
              +D++
Sbjct: 775 RSPADKF 781



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 132/625 (21%), Positives = 214/625 (34%), Gaps = 90/625 (14%)

Query: 104 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 163
           P P   P   P +  +S      T I++  EE   +  ++ +   +  E T   +   EV
Sbjct: 417 PIPFSLPEGLPKIPSVS------THIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470

Query: 164 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPAC 222
                K   E E                 E   P    P+E+   PE E+   +      
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP----PAEEAASPEKEAKSPVKEEAKS 526

Query: 223 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATA 281
           P+E+  P    A+ P E+ +   +         S PE ++ E   + +P  + S   A +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586

Query: 282 PS---ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAA 338
           P+   A SPA+ +  E+ +   + EA    EA+S    E   P E        S   E A
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646

Query: 339 AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 398
            + + A S  K   K  E  K            +A    PE    P       PE   S 
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV---------KAEAKSPEKAKSPVKAEAKSPEKAKS- 696

Query: 399 VPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQF 458
             P  EEA     +K      A++  P + K   K +   P    EK +           
Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKS--PEKAKSPVKEEAKTP----EKAK----------- 737

Query: 459 IFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRG 518
              S  K E              K+P +   P + +                  TL  + 
Sbjct: 738 ---SPVKEEA-------------KSPEKAKSPEKAK------------------TLDVKS 763

Query: 519 PPRGGPGGELPRGPAGLGPRRSQQGPRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSK 575
           P    P  E  R PA   P +++   ++E   P K  A   + ED K  + E   K   K
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVK 821

Query: 576 RTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVID 635
               ++++ +E     K ++  ++        TP+  ++  K   +     +E  K  ++
Sbjct: 822 SPVKEEEKPQE----VKVKEPPKKAEEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVE 875

Query: 636 LIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD 694
              E A+ +P  S   A         KVPT EK     V  ++    + + E  K + DD
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935

Query: 695 EVFEKKQKEMDEAATAEERGRLKEE 719
              ++  K  ++   A E+   KEE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEE 960


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 92/383 (24%), Positives = 123/383 (32%), Gaps = 67/383 (17%)

Query: 30   EEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS 89
            EE  S A    TP  P +     P     T   A +  P++ +  A     P  P    S
Sbjct: 1011 EEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT---S 1067

Query: 90   PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 149
            P+ + P+   PT SP+  +    EP     ++P     T   S   + P   E   P   
Sbjct: 1068 PAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPT---SPAAAVPTPEEPASPAAA 1123

Query: 150  SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPE 209
             P P   A P   V      P PE     +P   PTP  S +  +  P          PE
Sbjct: 1124 VPTPEEPASPAAAV------PTPEEPAFPAPA-VPTPEESASAAVAVPT---------PE 1167

Query: 210  VESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLS-----------PVSEP 257
              +SP  A P PA  +     +A   +P       P+P A+  +           P SE 
Sbjct: 1168 ESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE 1227

Query: 258  EEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGE 317
                    ++   PT P+A   T    TS A               A      E      
Sbjct: 1228 PASLAAAVSNPEEPTSPAAAVPTLEEPTSSA---------------AAVLTPEELSSPAA 1272

Query: 318  ELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAV 377
             +  PE    PA    NLE  A+   AV  P+                 + A   A+   
Sbjct: 1273 SVPTPEEPASPAAAVSNLEEPASPAAAVPTPE-----------------VAAIPAASVPT 1315

Query: 378  PEVENQPPAGSNPGPESEGSGVP 400
            PEV   P A   P  E    GVP
Sbjct: 1316 PEVPAIPAAAVPPMEEVSPIGVP 1338



 Score = 61.2 bits (147), Expect = 7e-09
 Identities = 97/402 (24%), Positives = 132/402 (32%), Gaps = 43/402 (10%)

Query: 26   KDITEEIMSGARTASTP----TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRP 81
            +D+T   +S    A+ P    + P+    +   ++ E    AV          A+    P
Sbjct: 894  EDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953

Query: 82   GLPGPEHS-PSESQPSSPSPTPSPSPVLEPGSEPNLAVL--SIPGDTMTTIQMSVEESTP 138
                   + P   +  +P    +P+  +    EP+ A +  S P +  +          P
Sbjct: 954  EWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013

Query: 139  ISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTVEIHEP 197
             S     P    P     A P  E   + +  VP  E  +SP  A PTP      E   P
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSP 1068

Query: 198  NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGA-----PSPPAVDLS 252
               VP+    PE  +SP  A P   P E   P A    PEE  + A     P  PA   +
Sbjct: 1069 AAAVPT----PEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122

Query: 253  PVSEPEEQAKEVTASMAP--PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEA 310
             V  PEE A    A   P  P  P+    T   + S A      EE            E+
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182

Query: 311  ESEKG-----GEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI----------K 355
             S         E   P  S P PA +   LE    T  A SVP                +
Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLE--EFTSPAASVPTSEEPASLAAAVSNPEE 1240

Query: 356  ELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGS 397
              +   AV  L +    A   +   E   PA S P PE   S
Sbjct: 1241 PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 66/294 (22%), Positives = 105/294 (35%), Gaps = 27/294 (9%)

Query: 30   EEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS 89
            EE  S A    TP  P +     P     T   A +  P++ +  A     P  P    +
Sbjct: 1063 EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAA 1122

Query: 90   --PSESQPSSPS---PTPS----PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPIS 140
              P+  +P+SP+   PTP     P+P +    E   A +++P    +    +   +   S
Sbjct: 1123 AVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES 1182

Query: 141  RETGEPYRLSPEPTPLAEPI---------LEVEVTLSKPVPESEFSSSPLQA------PT 185
                       EPT  A  +         LE   + +  VP SE  +S   A      PT
Sbjct: 1183 ASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242

Query: 186  PLASHTVEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAP 244
              A+    + EP     +  L PE  SSP  + P P  P+     ++   +P       P
Sbjct: 1243 SPAAAVPTLEEPTSSAAAV-LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP 1301

Query: 245  SPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 298
            +P    +   S P  +   + A+  PP +   +P   P     A  + +   EE
Sbjct: 1302 TPEVAAIPAASVPTPEVPAIPAAAVPP-MEEVSPIGVPFLGVSAHTDSVPISEE 1354



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 95/375 (25%), Positives = 124/375 (33%), Gaps = 63/375 (16%)

Query: 62   VAVIVRPDDRSQGAIIADR--PGLPGPEHSPSESQPSSPSPT-------PSPSPVLEPGS 112
            + V+ RP   +    + D     LP PE   S +   +P  T       P P   +   S
Sbjct: 828  IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887

Query: 113  EPNL-------AVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSP--------EPTPL 156
              +L       A +S P   T+  + +SV E T        P   +P        E    
Sbjct: 888  IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947

Query: 157  AEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPEL 216
                      L+  VP +E   +P    TP    TV   E           PE  +SP  
Sbjct: 948  VAGFSPEWAALAITVPITEEDGTPEGPVTPAT--TVHAPEEPDTAAVRVSTPEEPASPAA 1005

Query: 217  APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSA 276
            A P   P E   P A    PEE     P+ PA  + P  EP   A  V  +   PT P+A
Sbjct: 1006 AVP--TPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEEPTSPAAAV-PTPEEPTSPAA 1057

Query: 277  TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLE 336
               T    TSPA    +   EE     A      E       +  PE    PA      E
Sbjct: 1058 AVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115

Query: 337  AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANP--AVPEVENQP-PAGSNPGPE 393
              A+   AV  P+                     + A+P  AVP  E    PA + P PE
Sbjct: 1116 EPASPAAAVPTPE---------------------EPASPAAAVPTPEEPAFPAPAVPTPE 1154

Query: 394  SEGSG--VPPRPEEA 406
               S     P PEE+
Sbjct: 1155 ESASAAVAVPTPEES 1169



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 15/174 (8%)

Query: 29   TEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLP-GPE 87
            +EE  S A   S P  P +     P     T   A ++ P++ S  A     P  P  P 
Sbjct: 1225 SEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPA 1284

Query: 88   HSPSE-SQPSSPS---PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP---IS 140
             + S   +P+SP+   PTP  +  +   S P   V +IP   +  ++       P   +S
Sbjct: 1285 AAVSNLEEPASPAAAVPTPEVA-AIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVS 1343

Query: 141  RETGEPYRLSPEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLAS 189
              T +   +S E TP+ E      + + + +        E +S+ L    PLA+
Sbjct: 1344 AHT-DSVPISEEGTPVLEEASSTGMWIKEDLDSLVFGIKEVTSTVLHGKVPLAA 1396


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%)

Query: 86   PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
            P   P  S    PS  P PS    P +  N   LS+PG      ++        +    +
Sbjct: 678  PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737

Query: 146  PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 199
            P  L+P  TP   P +  + T    VP   F       +S ++      S    +  P G
Sbjct: 738  PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794

Query: 200  MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 253
            + P     P   + P +AP    P+ SP P+    +PEEL      L   P PP     P
Sbjct: 795  LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852

Query: 254  VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 311
            V+ P  Q   +       PP +         +++   +EEE EEEEEEEE E  E    E
Sbjct: 853  VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912

Query: 312  SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 371
             E+  EE    E         +  E            +   + +EL + E + +   A  
Sbjct: 913  EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970

Query: 372  EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 425
            E     P     PPA   P PES     P P PE     E +E    +E     A  + P
Sbjct: 971  EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 28/312 (8%)

Query: 42   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 101
            P PP +G    P A    P  +  V   +  +     + P  PGP   P    P  P P 
Sbjct: 799  PPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----ELPAAPGPLPPPPPPPPPVPGPV 853

Query: 102  PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EESTPISRETGEPYRLSPEPTPLAE 158
              P P L P   P         + +T I ++    EE      E  E      E     E
Sbjct: 854  TLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913

Query: 159  PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--HEPNGMVPSEDLE-----PEVE 211
               E E    +   E EF     +    L     E    E   +   EDLE      EVE
Sbjct: 914  EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973

Query: 212  SSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAVDLSPVSEP---EEQAKEVTAS 267
                  PPP  P   P P +P   QPE      P P    L  V EP   EE+  +   +
Sbjct: 974  EGAP--PPPTLPPALPPPESPPKVQPE------PEPEPGLLLEVEEPGTEEERGADTAPT 1025

Query: 268  MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 327
            +AP  +PS          SPA     +E  EEE        E E+E G +++ PP  TP 
Sbjct: 1026 LAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084

Query: 328  PANLSQNLEAAA 339
               +    EA A
Sbjct: 1085 EEEMETETEAEA 1096



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%)

Query: 155 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 214
           P   P+  +  T   P P       P +AP+P  +     H P  M       P V S P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678

Query: 215 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 270
              P P+    PS  PVP A    P    + G   P  V + P   P  +     ++  P
Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738

Query: 271 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 323
              PS TP     P  T   +         ++EE  +   + E++S+       E LPP 
Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798

Query: 324 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 383
             P P+  +    A      A      + + +EL    A    L       P VP     
Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855

Query: 384 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 433
           PP    P   + G G PP  EE         +DE  + +E++    E  +  E+ +E + 
Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914

Query: 434 --SDQWKPLNLEEKKRYDREF 452
              +++     EE++ ++ EF
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%)

Query: 684 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 722
           +++FE++++D+E +   E++++E  E    EE G L+EE EE
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 44/250 (17%)

Query: 35  GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 94
           GA  A    PPQ G     +   E+P+      P            P  P P  +P    
Sbjct: 4   GAAAAQGTAPPQDG-----EQPAESPEPPPPWPPP-----------PPPPAPPPAPPLLS 47

Query: 95  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 154
            +SP P P P P L PG  P     S    T    + + E +T  + E        P P 
Sbjct: 48  EASPEPIPEPCPELAPGPCPEATSESA---TELYTEPTPEPATEPASEPAPEPATEPAPE 104

Query: 155 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 214
           P  EP  E       P PE    S+P   P P      E        P+ +L PEV  +P
Sbjct: 105 PATEPAPE-------PAPEPATESAPEPTPEPALESVPE--------PAPELTPEV--AP 147

Query: 215 ELAPPPACPSESPVPIAPTAQPEELLNGAPSP-PAVDLSPVSEPEEQAKEVTASMAPPTI 273
           ELAP P    E    +AP   PE      PSP P +   PV   E   K      +P   
Sbjct: 148 ELAPEPT--PEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK-----TSPSPS 200

Query: 274 PSATPATAPS 283
           PS +P T  S
Sbjct: 201 PSPSPRTPMS 210



 Score = 44.7 bits (104), Expect = 7e-04
 Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 19/159 (11%)

Query: 142 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 201
           + GE    SPEP P   P          P   SE S  P+  P P  +         G  
Sbjct: 15  QDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP--------GPC 66

Query: 202 PSEDLEPEVESSPELAPPPAC-PSESPVPIAPTAQ-PEELLNGAPSP---PAVDLSPVSE 256
           P    E   E   E  P PA  P+  P P   T   PE     AP P   PA + +P   
Sbjct: 67  PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPT 126

Query: 257 PEEQAKEVTASMAPPTIPSATPATAPS-ATSPAQEEEME 294
           PE   + V     P   P  TP  AP  A  P  E   E
Sbjct: 127 PEPALESV-----PEPAPELTPEVAPELAPEPTPEPVTE 160



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 44/141 (31%), Positives = 52/141 (36%), Gaps = 20/141 (14%)

Query: 199 GMVPSEDLEPEVESS----------PELAPPPACPSESPVPIAPTAQPEELLNGAPSPPA 248
           G  P +D E   ES           P  APPPA P  S     P  +P   L   P P A
Sbjct: 10  GTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69

Query: 249 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 308
              S      E   E      P T P++ PA  P AT PA E   E   E     A E+ 
Sbjct: 70  TSESATELYTEPTPE------PATEPASEPAPEP-ATEPAPEPATEPAPEPAPEPATESA 122

Query: 309 EAESEKGGEELLP---PESTP 326
              + +   E +P   PE TP
Sbjct: 123 PEPTPEPALESVPEPAPELTP 143


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%)

Query: 35  GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 90
           G  TA        G  L P+      G  P+   +      SQ +I A   G    +  P
Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 633

Query: 91  SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 146
           +  QPS   P+P     L  G+E P     S+PG           + +P S   G P   
Sbjct: 634 AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 692

Query: 147 -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 198
                Y   P  TP   P  +    +LS+P P    +    + P  + L S+      P 
Sbjct: 693 PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 752

Query: 199 GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 247
                      V +SP + P PA  +      A       P   P + L+     +P PP
Sbjct: 753 RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 805

Query: 248 AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 303
            +D SP   P+E A    +   +  A P+ P   PA A  A+   +EE   E      G 
Sbjct: 806 PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 863

Query: 304 AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 355
           +GE G   +E+G   +         PP  TP+P  L  NL  +          KRR K +
Sbjct: 864 SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 915

Query: 356 ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 400
           E   +E +   L AF  A+    PA     P     PPA S P PE       GVP
Sbjct: 916 E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 968



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 79/329 (24%), Positives = 117/329 (35%), Gaps = 54/329 (16%)

Query: 37   RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 96
            R    P PP+    +    +G +P+   +       +GA    R  L  P        P 
Sbjct: 783  RKGPPPPPPKRLSSV----SGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPP 838

Query: 97   SPSPTPSPSPVLEPGSEPNLAVLSIPGDTM-------TTIQMSVEESTPISRETGEP--- 146
            +P+   S +   EPG E         G+ +        TI+   + + P  RET  P   
Sbjct: 839  APAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGL 898

Query: 147  -YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS---HT 191
             + L+   T           PL   +L   V  + P P     ++PL +PTP  S    +
Sbjct: 899  DFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGESPPASS 953

Query: 192  VEIHEPNGMVPSEDLEPEVESSPELAPP-PACPSESPVPIA---------PTAQPEELLN 241
            +   EP+ + P++ +   +  SP + PP P CP       A         P A P  LL 
Sbjct: 954  LPQPEPSSL-PAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLK 1012

Query: 242  --GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSAT---SPAQEEEMEEE 296
              GA + P     PVS    Q       +AP   P   P   P +T    P Q ++  E+
Sbjct: 1013 VPGAGTAP----KPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQ 1068

Query: 297  EEEEEGEAGEAGEAESEKGGEELLPPEST 325
                   A  A E       +E  P  ST
Sbjct: 1069 TSSSLAAALRAAEKSIGTKEQEGTPSAST 1097



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%)

Query: 36   ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 86
            AR    P PP       +G   EP    E+P   + A   R    S+ A  ++ PG P P
Sbjct: 781  ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 840

Query: 87   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 146
                S+++   P P  +P     P    +   L    +   TI+   + + P  RET  P
Sbjct: 841  AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 895

Query: 147  ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 191
                + L+   T           PL   +L   V  + P P     ++PL +PTP  S  
Sbjct: 896  PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 948

Query: 192  VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 251
                            P   S P+  P        P P+AP+   +  +   P  P ++ 
Sbjct: 949  ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 991

Query: 252  SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 288
            S  S    + +   A  A   +P A   TAP   S A
Sbjct: 992  SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1026



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%)

Query: 34   SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 86
            +G     TP PP     L      +T +     R  +  Q A++A         P  P P
Sbjct: 885  AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 941

Query: 87   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 146
              +P ES P+S  P P PS +   G    LA        +        ES+  SR  GE 
Sbjct: 942  SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1000

Query: 147  YRLSPEPTPLAEPILEVEVTLSKPVPES 174
                 EP      +L+V    + P P S
Sbjct: 1001 ----TEPPAAPAALLKVPGAGTAPKPVS 1024


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%)

Query: 35   GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 90
            G  TA        G  L P+      G  P+   +      SQ +I A   G    +  P
Sbjct: 656  GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 715

Query: 91   SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 146
            +  QPS   P+P     L  G+E P     S+PG           + +P S   G P   
Sbjct: 716  AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 774

Query: 147  -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 198
                 Y   P  TP   P  +    +LS+P P    +    + P  + L S+      P 
Sbjct: 775  PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 834

Query: 199  GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 247
                       V +SP + P PA  +      A       P   P + L+     +P PP
Sbjct: 835  RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 887

Query: 248  AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 303
             +D SP   P+E A    +   +  A P+ P   PA A  A+   +EE   E      G 
Sbjct: 888  PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 945

Query: 304  AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 355
            +GE G   +E+G   +         PP  TP+P  L  NL  +          KRR K +
Sbjct: 946  SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 997

Query: 356  ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 400
            E   +E +   L AF  A+    PA     P     PPA S P PE       GVP
Sbjct: 998  E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 1050



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 79/329 (24%), Positives = 117/329 (35%), Gaps = 54/329 (16%)

Query: 37   RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 96
            R    P PP+    +    +G +P+   +       +GA    R  L  P        P 
Sbjct: 865  RKGPPPPPPKRLSSV----SGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPP 920

Query: 97   SPSPTPSPSPVLEPGSEPNLAVLSIPGDTM-------TTIQMSVEESTPISRETGEP--- 146
            +P+   S +   EPG E         G+ +        TI+   + + P  RET  P   
Sbjct: 921  APAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGL 980

Query: 147  -YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLAS---HT 191
             + L+   T           PL   +L   V  + P P     ++PL +PTP  S    +
Sbjct: 981  DFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGESPPASS 1035

Query: 192  VEIHEPNGMVPSEDLEPEVESSPELAPP-PACPSESPVPIA---------PTAQPEELLN 241
            +   EP+ + P++ +   +  SP + PP P CP       A         P A P  LL 
Sbjct: 1036 LPQPEPSSL-PAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAALLK 1094

Query: 242  --GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSAT---SPAQEEEMEEE 296
              GA + P     PVS    Q       +AP   P   P   P +T    P Q ++  E+
Sbjct: 1095 VPGAGTAP----KPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQAQQRLEQ 1150

Query: 297  EEEEEGEAGEAGEAESEKGGEELLPPEST 325
                   A  A E       +E  P  ST
Sbjct: 1151 TSSSLAAALRAAEKSIGTKEQEGTPSAST 1179



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%)

Query: 36   ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 86
            AR    P PP       +G   EP    E+P   + A   R    S+ A  ++ PG P P
Sbjct: 863  ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 922

Query: 87   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 146
                S+++   P P  +P     P    +   L    +   TI+   + + P  RET  P
Sbjct: 923  AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 977

Query: 147  ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 191
                + L+   T           PL   +L   V  + P P     ++PL +PTP  S  
Sbjct: 978  PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 1030

Query: 192  VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 251
                            P   S P+  P        P P+AP+   +  +   P  P ++ 
Sbjct: 1031 ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 1073

Query: 252  SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 288
            S  S    + +   A  A   +P A   TAP   S A
Sbjct: 1074 SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1108



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%)

Query: 34   SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 86
            +G     TP PP     L      +T +     R  +  Q A++A         P  P P
Sbjct: 967  AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 1023

Query: 87   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 146
              +P ES P+S  P P PS +   G    LA        +        ES+  SR  GE 
Sbjct: 1024 SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1082

Query: 147  YRLSPEPTPLAEPILEVEVTLSKPVPES 174
                 EP      +L+V    + P P S
Sbjct: 1083 ----TEPPAAPAALLKVPGAGTAPKPVS 1106


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
           P ++P+ +  S P+ TPS +P L P S+P L   S P  T ++       +TP    +  
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 146 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205
           P  L+P  TP   P     +T   P P    SS+P    TP +  T+       + PS  
Sbjct: 64  P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117

Query: 206 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 259
                 ++P L P   P   PS +P  + P+++P  +L  + +P    L+P S P     
Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171

Query: 260 QAKEVTASMAPPTIPSATPATAPSAT 285
               +T S  P   PS+TP   PS+T
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%)

Query: 43  TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 102
           TP  T           TP +     P    Q  +         P   P+ +  ++P+ TP
Sbjct: 55  TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114

Query: 103 SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 162
           S +P L P + P L   S P  T ++       S PI   +      +P  TP + PIL 
Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169

Query: 163 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 219
              T +   P S  + +P   PT   S T        + PS        S+P L P   P
Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222

Query: 220 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 279
              PS +P  + P+++P  +L  + +P     S  +        +T S  P   PS TP 
Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 280 TAPSAT 285
             PS+T
Sbjct: 280 LTPSST 285



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
           P   P  ++ S+P+ TPS +P L P + P L     P +T T    +    TP S  T  
Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287

Query: 146 PYRLSPEPTPLAEP 159
              L+P  TP   P
Sbjct: 288 ---LTPSSTPTLTP 298



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 129
           P ++P+ +  ++P+ TPS +P L P S P L   S P  T +++
Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 172 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 231
           P +  + +P   PT   S T  +   +  + +    P +  S   +PP   PS +P  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59

Query: 232 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 287
           P+  P    +  P+     L+P S P    + +    + PT+  ++P T   + +P
Sbjct: 60  PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
           P ++P+ +  S P+ TPS +P L P S+P L   S P  T ++       +TP    +  
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 146 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 205
           P  L+P  TP   P     +T   P P    SS+P    TP +  T+       + PS  
Sbjct: 64  P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117

Query: 206 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 259
                 ++P L P   P   PS +P  + P+++P  +L  + +P    L+P S P     
Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171

Query: 260 QAKEVTASMAPPTIPSATPATAPSAT 285
               +T S  P   PS+TP   PS+T
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%)

Query: 43  TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 102
           TP  T           TP +     P    Q  +         P   P+ +  ++P+ TP
Sbjct: 55  TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114

Query: 103 SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 162
           S +P L P + P L   S P  T ++       S PI   +      +P  TP + PIL 
Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169

Query: 163 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 219
              T +   P S  + +P   PT   S T        + PS        S+P L P   P
Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222

Query: 220 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 279
              PS +P  + P+++P  +L  + +P     S  +        +T S  P   PS TP 
Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 280 TAPSAT 285
             PS+T
Sbjct: 280 LTPSST 285



 Score = 37.0 bits (84), Expect = 0.14
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
           P   P  ++ S+P+ TPS +P L P + P L     P +T T    +    TP S  T  
Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287

Query: 146 PYRLSPEPTPLAEP 159
              L+P  TP   P
Sbjct: 288 ---LTPSSTPTLTP 298



 Score = 32.7 bits (73), Expect = 2.6
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 129
           P ++P+ +  ++P+ TPS +P L P S P L   S P  T +++
Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 172 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 231
           P +  + +P   PT   S T  +   +  + +    P +  S   +PP   PS +P  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59

Query: 232 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 287
           P+  P    +  P+     L+P S P    + +    + PT+  ++P T   + +P
Sbjct: 60  PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 20/230 (8%)

Query: 68  PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 127
           P +     +    P    P ++P+ +  S+P+ TP  +P L P + P L   S P  T +
Sbjct: 46  PREMGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPS 105

Query: 128 TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--- 184
           +       STP    +  P  L+P  TP   P     +T S   P    SS+P   P   
Sbjct: 106 STPTLTPSSTPTLTPSSTP-TLTPSSTPTLTPSSTPTLTRSS-TPTLTPSSTPTLTPSST 163

Query: 185 ---TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---PPACPSESPVPIAPTAQPEE 238
              TP ++ T+       + PS        S+P L P   P   PS +P  + P+  P  
Sbjct: 164 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPT-LTPSNTPTL 222

Query: 239 LLNGAPSPPAVDLSPVSEP---EEQAKEVTASMAPPTIPSATPATAPSAT 285
           + +  P+     L+P S P         +T S  P   PS+TP   PS+T
Sbjct: 223 IPSSTPT-----LTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSST 267



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 19/53 (35%), Positives = 27/53 (50%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP 138
           P ++P+    S+P+ TPS +P L P S P L   S P  T ++       STP
Sbjct: 216 PSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSSTP 268



 Score = 35.0 bits (79), Expect = 0.52
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 9/74 (12%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 145
           P  +P+ +  ++P+  PS +P L P S P L   S P  T ++       STP       
Sbjct: 208 PSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTP------- 260

Query: 146 PYRLSPEPTPLAEP 159
              L+P  TP   P
Sbjct: 261 --TLTPSSTPTLTP 272



 Score = 31.6 bits (70), Expect = 5.7
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 86  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSI 121
           P   P+ ++ S+P+ TPS +P L P S P L   S+
Sbjct: 240 PSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSL 275


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 72/322 (22%), Positives = 109/322 (33%), Gaps = 52/322 (16%)

Query: 32   IMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPS 91
            ++S       P PP  G    P      P++A+ VRP   +  +I A  P    P  +P+
Sbjct: 843  VVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPT 902

Query: 92   ESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 151
             + P    P P P P+  P + P  A   IP     +  +      P         R+ P
Sbjct: 903  PAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP---------RIGP 953

Query: 152  EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 211
            +P P  +           P P   F   P Q P PL    +   +  G++P +   P   
Sbjct: 954  QPQPHPQ-----------PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAP 1002

Query: 212  SSPELAPPP--------ACPSESPVPI----------APTAQPEELLNGAPSPPAVDLSP 253
                L  PP          P++ P+P            P   P   L   P+P    + P
Sbjct: 1003 QPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGP 1062

Query: 254  VSEPEEQAKEVTASMAPPT---IPSATPATAPSATSPAQEEEMEEEEEEEEGEA------ 304
             + P       +A  + P+   +PS  P+  P    P +    E       G A      
Sbjct: 1063 QAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAEPPPCLRRGAAAADLLS 1121

Query: 305  ----GEAGEAESEKGGEELLPP 322
                 + G  +S  GG+ LL P
Sbjct: 1122 SSPESQHGGTQSPGGGQPLLQP 1143



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 79/336 (23%), Positives = 116/336 (34%), Gaps = 55/336 (16%)

Query: 4    PPQIAPKRER-KTIRIRDPNQGGKDITEEIMSGARTAST----PTPPQTGGGLEPQANGE 58
            P  + P+RE  + +   DP +  + +  ++++G R   T     TP        P + G 
Sbjct: 723  PKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGP 782

Query: 59   TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS-PSPTPSPSPVLEPGSEPNLA 117
             P       P     G     +P  PGP   P    P+  P+P  +P   L P S P   
Sbjct: 783  GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHG 842

Query: 118  VLSI-------------------PGDTMTTIQMSVEEST--------PISRETGEPYRLS 150
            V+S                    P  +   + M+V  +T        PI   T      +
Sbjct: 843  VVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPT 902

Query: 151  PEPTPLAEPI-----LEVEVT----LSKPVPESEFSSSPLQA--PTPLASHTVEIH-EPN 198
            P P P   P+     L    T      +P+P     SS + A  P P      + H +P+
Sbjct: 903  PAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPH 962

Query: 199  ---GMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELLNGAPSPPAVDLS 252
                  P    +P     P L PP A    P +SP P AP  QP  L  G P PP     
Sbjct: 963  PSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAP--QPGVL--GQPPPPLHTQL 1018

Query: 253  PVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 288
                 ++     + ++  P+     P   P A  PA
Sbjct: 1019 YPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPA 1054



 Score = 32.3 bits (72), Expect = 3.4
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%)

Query: 155  PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 214
            P  +P+    ++    +P+       L    P++S    I + + + P   LE  V S P
Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521

Query: 215  ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 274
              A PP  P        P + PE     + SPP     P+S P  +A +       P  P
Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568

Query: 275  SATPATA 281
            S+ P ++
Sbjct: 1569 SSGPPSS 1575


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,342,562
Number of Sequences: 37866
Number of extensions: 3906331
Number of successful extensions: 49492
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 468
Number of HSP's successfully gapped in prelim test: 1936
Number of HSP's that attempted gapping in prelim test: 26120
Number of HSP's gapped (non-prelim): 15962
length of query: 1435
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1320
effective length of database: 13,892,928
effective search space: 18338664960
effective search space used: 18338664960
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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