BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sapiens] (1403 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ... 2784 0.0 gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ... 1171 0.0 gi|110630018 eukaryotic translation initiation factor 4 gamma, 2... 196 1e-49 gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i... 196 1e-49 gi|33386693 poly(A) binding protein interacting protein 1 isofor... 81 8e-15 gi|17511255 poly(A) binding protein interacting protein 1 isofor... 81 8e-15 gi|169212085 PREDICTED: similar to poly(A) binding protein inter... 78 7e-14 gi|239752553 PREDICTED: similar to poly(A) binding protein inter... 78 7e-14 gi|89041275 PREDICTED: similar to poly(A) binding protein intera... 78 7e-14 gi|34452730 poly(A) binding protein interacting protein 1 isofor... 77 9e-14 gi|163965366 nascent polypeptide-associated complex alpha subuni... 75 3e-13 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 1e-12 gi|116284392 mucin 2 precursor [Homo sapiens] 72 4e-12 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 4e-12 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 72 4e-12 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 5e-12 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 71 8e-12 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 71 8e-12 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 69 3e-11 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 67 9e-11 gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 67 9e-11 gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 67 9e-11 gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 67 1e-10 gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 67 1e-10 gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 67 2e-10 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 65 5e-10 >gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 197 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256 Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 257 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 317 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376 Query: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 377 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436 Query: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496 Query: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 497 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556 Query: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 557 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616 Query: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 617 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676 Query: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 677 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736 Query: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 737 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796 Query: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 797 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856 Query: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 857 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916 Query: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 917 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976 Query: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 977 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036 Query: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096 Query: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156 Query: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216 Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276 Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336 Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396 Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456 Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516 Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576 Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403 VALKSVTAFFKWLREAEEESDHN Sbjct: 1577 VALKSVTAFFKWLREAEEESDHN 1599 Score = 33.5 bits (75), Expect = 1.5 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%) Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118 P S P P+PSP L + P PG T + + + +TP R+ P R Sbjct: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 Query: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173 P P+ A + P S+ P Q P + I G S Sbjct: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113 Query: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221 + P + + P P SP P ++ G AP+P ++ P Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173 Query: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265 + +P + K++T + + PT P P A Q + + Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233 Query: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322 + +G A G E E P +P P+ S LE + +AV S+P Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292 Query: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376 +++ +E+ G+ E P + S P PESE S P +A Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349 Query: 377 TWDSKEDKIHNAENIQPGE 395 S +IH + P E Sbjct: 350 PLASHTVEIHEPNGMVPSE 368 >gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 isoform 2 [Homo sapiens] Length = 1512 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 110 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 169 Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 170 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 229 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 230 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 289 Query: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 290 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 349 Query: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 350 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 409 Query: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 410 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 469 Query: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 470 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 529 Query: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 530 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 589 Query: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 590 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649 Query: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 650 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709 Query: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 710 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 769 Query: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 770 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 829 Query: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 830 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 889 Query: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 890 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 949 Query: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 950 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1009 Query: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 1010 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1069 Query: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 1070 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1129 Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1130 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1189 Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1190 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1249 Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1250 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1309 Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1310 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1369 Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1370 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1429 Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1430 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1489 Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403 VALKSVTAFFKWLREAEEESDHN Sbjct: 1490 VALKSVTAFFKWLREAEEESDHN 1512 >gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 isoform 3 [Homo sapiens] Length = 1435 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 33 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 92 Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 93 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 152 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 153 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 212 Query: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 213 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 272 Query: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 273 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 332 Query: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 333 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 392 Query: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 393 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 452 Query: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 453 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 512 Query: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 513 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 572 Query: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 573 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 632 Query: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 633 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 692 Query: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 693 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 752 Query: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 753 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 812 Query: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 813 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 872 Query: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 873 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 932 Query: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 933 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 992 Query: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 993 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1052 Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1053 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1112 Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1113 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1172 Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1173 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1232 Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1233 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1292 Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1293 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1352 Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1353 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1412 Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403 VALKSVTAFFKWLREAEEESDHN Sbjct: 1413 VALKSVTAFFKWLREAEEESDHN 1435 >gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 isoform 1 [Homo sapiens] Length = 1599 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 197 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256 Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 257 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 317 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376 Query: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 377 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436 Query: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 437 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496 Query: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 497 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556 Query: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 557 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616 Query: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 617 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676 Query: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 677 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736 Query: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 737 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796 Query: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 797 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856 Query: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 857 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916 Query: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 917 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976 Query: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 977 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036 Query: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096 Query: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156 Query: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216 Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276 Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336 Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396 Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456 Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516 Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576 Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403 VALKSVTAFFKWLREAEEESDHN Sbjct: 1577 VALKSVTAFFKWLREAEEESDHN 1599 Score = 33.5 bits (75), Expect = 1.5 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%) Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118 P S P P+PSP L + P PG T + + + +TP R+ P R Sbjct: 5 PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57 Query: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173 P P+ A + P S+ P Q P + I G S Sbjct: 58 P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113 Query: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221 + P + + P P SP P ++ G AP+P ++ P Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173 Query: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265 + +P + K++T + + PT P P A Q + + Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233 Query: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322 + +G A G E E P +P P+ S LE + +AV S+P Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292 Query: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376 +++ +E+ G+ E P + S P PESE S P +A Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349 Query: 377 TWDSKEDKIHNAENIQPGE 395 S +IH + P E Sbjct: 350 PLASHTVEIHEPNGMVPSE 368 >gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 isoform 4 [Homo sapiens] Length = 1403 Score = 2784 bits (7218), Expect = 0.0 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%) Query: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE Sbjct: 1 MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE Sbjct: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES Sbjct: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 Query: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT Sbjct: 181 SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240 Query: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS Sbjct: 241 IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300 Query: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP Sbjct: 301 QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360 Query: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF Sbjct: 361 ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420 Query: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT Sbjct: 421 LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480 Query: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP Sbjct: 481 TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540 Query: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG Sbjct: 541 SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600 Query: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD Sbjct: 601 VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660 Query: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM Sbjct: 661 DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720 Query: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR Sbjct: 721 HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780 Query: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP Sbjct: 781 FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840 Query: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG Sbjct: 841 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900 Query: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD Sbjct: 901 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960 Query: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR Sbjct: 961 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020 Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080 Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140 Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200 Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260 Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320 Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380 Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403 VALKSVTAFFKWLREAEEESDHN Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403 >gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo sapiens] Length = 1585 Score = 1171 bits (3029), Expect = 0.0 Identities = 728/1489 (48%), Positives = 912/1489 (61%), Gaps = 166/1489 (11%) Query: 5 RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 64 R STPTPPQ L Q +P V V + A +A + E +P Sbjct: 173 RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223 Query: 65 SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 106 SPSPVL E + ++A L +P T++++ S + Sbjct: 224 PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283 Query: 107 ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 153 S + +P SP + P L S P+P +E + P Sbjct: 284 SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343 Query: 154 ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 209 PL S T I+E NG+ SE L ES E+ P + I E L Sbjct: 344 PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400 Query: 210 GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 265 P+P ++P + P T +PP P PA A + +SP+ + +EE+E Sbjct: 401 CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456 Query: 266 E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 314 E+ E E E++ EE+L ++ +P+PA Q+A++ Sbjct: 457 SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504 Query: 315 VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 370 VPK +K K+ + +E + L+ E ++ +V + G PE + S + + Sbjct: 505 VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563 Query: 371 PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 415 + +E + E + AE++ GE + +K + WKP + E KK+ Sbjct: 564 VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623 Query: 416 YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 473 YDREFLL FQF+ A +QKPEGLP ISDVVLDK N K P+R LDP L GPDFTP+ Sbjct: 624 YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680 Query: 474 FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 533 FA+ GR T RG P +G RRSQ G R+EPRKII TV + ED+ L K Sbjct: 681 FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728 Query: 534 AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 593 AE AWKPS KR D +D + KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D Sbjct: 729 AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783 Query: 594 TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 653 TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP +KP TVNFRKLLLNRCQK Sbjct: 784 TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843 Query: 654 EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 713 EFEKDK DD+VFEKKQKE++ A+ EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK Sbjct: 844 EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903 Query: 714 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 773 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+ Sbjct: 904 MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963 Query: 774 KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 833 KTSSRIRFMLQDV+DLR NWV RR DQGPKTI+QIHKEA++EE E KVQQLM K + Sbjct: 964 KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021 Query: 834 KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 893 KRR G+ VD+GGWNTV +K SR +D S+ KITKP +ID QL Sbjct: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071 Query: 894 RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 945 SWGKGSSGG+ A +D A R + S+LNRFSALQ P+ ST D+RR + Sbjct: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127 Query: 946 QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1004 R S+ RE+ +K R RGG D LD ++ EE+ RE Sbjct: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176 Query: 1005 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1060 + L + + RE+A P +S + KAALSEEELE+KSK+II+E+LH+ Sbjct: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236 Query: 1061 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1120 ND KEA+QCV+EL + LL +FVR GVESTLERS I R+HMGQLL+QL+ + LS ++ Sbjct: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296 Query: 1121 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1180 +G E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL E +KPL P+G+A LL Sbjct: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356 Query: 1181 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1237 EIL LLCK M KKVG LWREA LSWK+FLPEG+D+ F+ EQK+++ + SEA Sbjct: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416 Query: 1238 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1296 ++ L +EEL ++LEKL+ E +N +++FDW+EANL E Q+ S T +RALMTAVC +AII Sbjct: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476 Query: 1297 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1354 + + RVD AV+K R +L KYL D +KELQALYALQA +V L+QP NLLRMFFD LY Sbjct: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536 Query: 1355 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1403 DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N Sbjct: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585 >gi|110630018 eukaryotic translation initiation factor 4 gamma, 2 isoform 2 [Homo sapiens] Length = 869 Score = 196 bits (498), Expect = 1e-49 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%) Query: 511 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 567 G R P+ T +E + + A W P+ D A+ + D +FR+ Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80 Query: 568 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 627 VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139 Query: 628 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679 A P + P + FR+LL+++ Q EFE + +V++K++ + Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192 Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 733 L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+ Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247 Query: 734 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 792 E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307 Query: 793 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 843 +WVPR+ D GPKTI+QI ++A +++ I SD GP PP Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359 Score = 113 bits (282), Expect = 1e-24 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%) Query: 1032 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1090 P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + + Sbjct: 492 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551 Query: 1091 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1150 L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+ Sbjct: 552 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611 Query: 1151 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1210 + V + EL +PL G L L L L K + + L++++ ++ ++ Sbjct: 612 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666 Query: 1211 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1269 LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+ Sbjct: 667 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717 Query: 1270 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1314 N+S + V V LMT+ S+ + L + +L + + Sbjct: 718 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777 Query: 1315 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1373 +QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+ Sbjct: 778 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836 Query: 1374 AEQQGKGVALKSVTAFFKWLREAEEE 1399 E GKG AL V + WL AEEE Sbjct: 837 QEFPGKGKALFQVNQWLTWLETAEEE 862 >gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 isoform 1 [Homo sapiens] Length = 907 Score = 196 bits (498), Expect = 1e-49 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%) Query: 511 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 567 G R P+ T +E + + A W P+ D A+ + D +FR+ Sbjct: 21 GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80 Query: 568 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 627 VR ILNKLTP+ F +L ++ + ++++ LKGVI LI +KA+ EP +S YA +C L Sbjct: 81 VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139 Query: 628 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679 A P + P + FR+LL+++ Q EFE + +V++K++ + Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192 Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 733 L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+ LL+ Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247 Query: 734 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 792 E LECLC+++ T+G LD E+AK MDQYF +M ++ K+ +RIRF+LQD ++LR Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307 Query: 793 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 843 +WVPR+ D GPKTI+QI ++A +++ I SD GP PP Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359 Score = 113 bits (282), Expect = 1e-24 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%) Query: 1032 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1090 P + K S+EEL K ++ ++ EYL+ + EAV V+E+ +P L + + + Sbjct: 530 PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589 Query: 1091 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1150 L+RS +E L+ L G ++ + Q +L+ +E+DIP V YLA+ Sbjct: 590 LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649 Query: 1151 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1210 + V + EL +PL G L L L L K + + L++++ ++ ++ Sbjct: 650 AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704 Query: 1211 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1269 LPE +Q + L E E G L P +L ++L K +K S Q ++ WI+ Sbjct: 705 LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755 Query: 1270 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1314 N+S + V V LMT+ S+ + L + +L + + Sbjct: 756 DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815 Query: 1315 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1373 +QK+L D ++ ALYALQ P +L FF YD ++++E+AF +W+ Sbjct: 816 MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874 Query: 1374 AEQQGKGVALKSVTAFFKWLREAEEE 1399 E GKG AL V + WL AEEE Sbjct: 875 QEFPGKGKALFQVNQWLTWLETAEEE 900 >gi|33386693 poly(A) binding protein interacting protein 1 isoform 2 [Homo sapiens] Length = 400 Score = 80.9 bits (198), Expect = 8e-15 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%) Query: 505 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 564 P+++ + +P+ ++A VLM++ + +N E S + G ED L Sbjct: 26 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79 Query: 565 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 619 V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS Sbjct: 80 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139 Query: 620 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679 A +C L + + NFR+LLL RC+ E+E Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172 Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 727 +K++ + ++ R+R + F+GEL+ L++ + + + + + L Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228 Query: 728 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 784 N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288 Query: 785 DVLDLRGSNW 794 +++LR SNW Sbjct: 289 KLVELRSSNW 298 >gi|17511255 poly(A) binding protein interacting protein 1 isoform 1 [Homo sapiens] Length = 479 Score = 80.9 bits (198), Expect = 8e-15 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%) Query: 505 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 564 P+++ + +P+ ++A VLM++ + +N E S + G ED L Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158 Query: 565 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 619 V+ LN LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218 Query: 620 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679 A +C L + + NFR+LLL RC+ E+E Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251 Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 727 +K++ + ++ R+R + F+GEL+ L++ + + + + + L Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307 Query: 728 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 784 N +++L C +LL G L+ EK K M++ ++E ++ + S ++ ML Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367 Query: 785 DVLDLRGSNW 794 +++LR SNW Sbjct: 368 KLVELRSSNW 377 Score = 31.6 bits (70), Expect = 5.6 Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%) Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207 PNG P+E L+P P PPP E P P P A PE+ Sbjct: 32 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91 Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 264 P + D P E + +AP + + P PS S + E E+ Sbjct: 92 RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151 Query: 265 EEE 267 E+ Sbjct: 152 CED 154 >gi|169212085 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 516 Score = 77.8 bits (190), Expect = 7e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173 Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228 Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284 Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317 Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377 Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414 Score = 30.8 bits (68), Expect = 9.6 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%) Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207 PNG P+E L+P P PPP E P P P A PE+ Sbjct: 69 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 128 Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262 + P + D P E + +AP + P PS S + E E Sbjct: 129 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 186 >gi|239752553 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 457 Score = 77.8 bits (190), Expect = 7e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 56 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114 Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169 Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225 Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258 Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318 Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355 Score = 30.8 bits (68), Expect = 9.6 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%) Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207 PNG P+E L+P P PPP E P P P A PE+ Sbjct: 10 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 69 Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262 + P + D P E + +AP + P PS S + E E Sbjct: 70 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 127 >gi|89041275 PREDICTED: similar to poly(A) binding protein interacting protein 1 [Homo sapiens] Length = 488 Score = 77.8 bits (190), Expect = 7e-14 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%) Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537 P R P G LP L P+++ + +P+ ++A VL ++ + +N E Sbjct: 87 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145 Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592 S + G ED V+ LN LT P F+ ++Q + + Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200 Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652 T++ L+ + +LI+++A S PNFS A +C L + + NFR+LLL RC+ Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256 Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711 E+E +K++ + ++ R+R + F+GEL+ Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289 Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757 L++ + + + + + L N +++L C +LL G L+ EK K Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349 Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794 M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386 Score = 30.8 bits (68), Expect = 9.6 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%) Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207 PNG P+E L+P P PPP E P P P A PE+ Sbjct: 41 PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 100 Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262 + P + D P E + +AP + P PS S + E E Sbjct: 101 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 158 >gi|34452730 poly(A) binding protein interacting protein 1 isoform 3 [Homo sapiens] Length = 367 Score = 77.4 bits (189), Expect = 9e-14 Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%) Query: 515 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 574 +P+ ++A VLM++ + +N E S + G ED L V+ LN Sbjct: 3 KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56 Query: 575 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 629 LT P F+ ++Q + + T++ L+ +++LI+++A S PNFS A +C L Sbjct: 57 LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116 Query: 630 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 689 + + NFR+LLL RC+ E+E +K++ Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145 Query: 690 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 737 + ++ R+R + F+GEL+ L++ + + + + + L N +++L Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205 Query: 738 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794 C +LL G L+ EK K M++ ++E ++ + S ++ ML +++LR SNW Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 75.5 bits (184), Expect = 3e-13 Identities = 97/390 (24%), Positives = 140/390 (35%), Gaps = 83/390 (21%) Query: 3 GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62 GA T TPP GGL + P AV+ P + GP SP + Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG------------GPATSPPKGA 1309 Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122 P+ P+ TP PSP PG+ P + P T P+ Sbjct: 1310 PTPPAATP-PSPKGSPGTPPPKGAPTPPAVT--------------------------PPS 1342 Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P P L SK P + S + PTP A+ P M P P + P Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGGP-AMTP-----PSPKRGP 1393 Query: 183 ELAPPPACP-SESPVPIAPTAQPEELL--NGAPSPPAVDLSPVSEPEEQAKEVTASMAP- 238 + P P S + +P++P P + GA +P DL+P + K+ A+ AP Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453 Query: 239 --PTIPSAT-PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL---LPPES 292 P PS+ T P+ T P+ +E ++ +A + G L +P Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513 Query: 293 TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQP 352 +PA S + A T +S ++ L KEA+ P Sbjct: 1514 KEVPATPSSRRDPIAPTATLLS----KKTPATLAPKEAL-------------------IP 1550 Query: 353 PAGSNPGPESEGSGVPPRPEEADETWDSKE 382 PA + P P+ + P P+EA T SKE Sbjct: 1551 PAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578 Score = 65.5 bits (158), Expect = 4e-10 Identities = 96/404 (23%), Positives = 137/404 (33%), Gaps = 63/404 (15%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAII-----ADRPGLPGPEHSPSE 60 T +PTPP G P A V + P + +++ + P P P+ +P+ Sbjct: 852 TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911 Query: 61 SQ-----------------PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103 S P+SPSP +P+P P P + Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSPKWAPTPPA 967 Query: 104 STPISRETGEPYRLSPE--PTPLAEPILEVEVTLSKPVPE-SEFSSSPLQAPTPLASHTV 160 +TP S + G P SP+ PTP A + P P+ + SP APTP A V Sbjct: 968 ATPPSPK-GGPATPSPKGAPTPPA---------ATPPSPKGGPATPSPKGAPTPPA---V 1014 Query: 161 EIHEPNGMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELL---NGAPSP 214 P G P+ P+ S+P A PP+ P+ +P+P P L G P+ Sbjct: 1015 TPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073 Query: 215 PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 274 P++ P A + P PS A P A +P + + Sbjct: 1074 PSLK----GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129 Query: 275 AGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGD 333 A S KGG PP+ P PA + + AT PK G Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT----PPPKGAPTTPAATPPSPKGG 1185 Query: 334 LLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 372 L + P P P G P +G + PP P+ Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229 Score = 62.8 bits (151), Expect = 2e-09 Identities = 100/447 (22%), Positives = 155/447 (34%), Gaps = 78/447 (17%) Query: 3 GARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPDDRSQGAIIADRP----GLPGPEHS 57 G T TP GG P + G TP A P + A+ P +P P+ Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PSHKGGPAMTPPSPKRGPAIPSPKGD 1401 Query: 58 PSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP-----ISRE 110 P+ P SP P+ E + P+ L+ P T +++ + S P Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461 Query: 111 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT----------------- 153 G+P + P EP +V S ++ + +P+ APT Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521 Query: 154 ----PLASHTVEIHE--PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEE- 206 P+A + + P + P E L P + P PA P+ P P+++ Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581 Query: 207 -------LLNGAPSPPAVDLSP-VSEPEEQAKEVTASMAPPTIPS--ATPATAPSATSPA 256 GAPSP + + P V+ P + ++ PP+ ATPA + TSP Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641 Query: 257 QEEEMEEEEEEEEGE--------AGEAGEAESEKGGEELL-------PPESTPI---PAN 298 ++ +A + K G L PESTPI P Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701 Query: 299 LSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGDLLDAFKEAN-PAVPEVENQPPAGS 356 + ++AT + P + K A LL K+++ A + + P G Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761 Query: 357 NPGPESEGS---------GVPPRPEEA 374 PES+ S V P+PE A Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESA 1788 Score = 60.5 bits (145), Expect = 1e-08 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 36/378 (9%) Query: 3 GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62 GA T TPP GG + P + P + A P P+ + + Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA------ATPFPKGASTPPA 1037 Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES-TPISRETGEPYRLSPEP 121 + PSP SP+ P P ++P S++ + TP + P P Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097 Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQ-APTPLASHTVEIHEPNGMVPSEDLEPEVES 180 +P P + + P P+ ++ P + APT A+ P G + + P+ Sbjct: 1098 SPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATP--PPKGAP 1149 Query: 181 SPELAPPP------ACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEEQAKEV 232 + A PP A P P P A P G PSP +P + P Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---- 1205 Query: 233 TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 292 +A P+ P P T P+AT P+ + + + A S KGG PP+ Sbjct: 1206 KGGLATPS-PKGAP-TTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262 Query: 293 TPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 351 P PA +L+ AT P + G + + P P Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPATSPPKGAPTPPAATPP 1318 Query: 352 PPAGSNPGPESEGSGVPP 369 P GS P +G+ PP Sbjct: 1319 SPKGSPGTPPPKGAPTPP 1336 Score = 60.1 bits (144), Expect = 1e-08 Identities = 90/379 (23%), Positives = 119/379 (31%), Gaps = 61/379 (16%) Query: 3 GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62 GA T TPP GG + P P + P P P+ +P+ Sbjct: 938 GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-------PATPSPKGAPTPPA 990 Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122 + PSP P+ G+ AV TP SP+ + Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAV------------------TP----------PSPKGS 1022 Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P A P + T P S SP P P + T P +PS P S Sbjct: 1023 PAATPFPKGASTPPAATPPSP-KGSPAATPLPKGAPTT----PAATLPSPKGGPATPSLK 1077 Query: 183 ELAPPPACPSESPVPIAPTAQPEELLNGAPSPP-AVDLSP---VSEPEEQAKEVTASMAP 238 PPA SP T P+ GAP PP A SP ++ P + T + P Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPK----GAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133 Query: 239 P-------TIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPE 291 P T P T P+AT P+ + + + A S KGG P+ Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPSPK 1192 Query: 292 STP-IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVEN 350 P PA + + AT PK G L + P P Sbjct: 1193 GAPTTPAATPPSPKGGLAT----PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248 Query: 351 QPPAGSNPGPESEGSGVPP 369 P G P +G+ PP Sbjct: 1249 PSPKGGPATPPPKGAPTPP 1267 Score = 58.9 bits (141), Expect = 3e-08 Identities = 88/361 (24%), Positives = 124/361 (34%), Gaps = 67/361 (18%) Query: 52 PGPEHSPSESQPSSPSPTPSPSPV---------LEPGSEPNLAVLSIPGDTMTTIQMSVE 102 P HSP+ P SP P+PS V L P P +V+++P + + Sbjct: 850 PATTHSPT---PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906 Query: 103 ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 162 ++ +S + P + P P P S SP APTP A+ T Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPA----------------SPSPKGAPTPPAA-TPPS 949 Query: 163 HEPNGMVPSEDLEPEVES----SPELAPPPACPSESPVPIAPT--------AQPEELLNG 210 + PS P + SP+ P P +P P A T A P G Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KG 1007 Query: 211 APSPPAVDL-----SPVSEPEEQAKEVTASMAPPT---IPSATP-----ATAPSATSPAQ 257 AP+PPAV SP + P + + PP+ P+ATP T P+AT P+ Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067 Query: 258 EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVP 316 + + A S KGG P+ P+ PA + + AT P Sbjct: 1068 KGG-PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126 Query: 317 KRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRP 371 K G L + P P P G P +G + PP P Sbjct: 1127 TTPAATPPSPK----GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182 Query: 372 E 372 + Sbjct: 1183 K 1183 Score = 43.1 bits (100), Expect = 0.002 Identities = 55/248 (22%), Positives = 96/248 (38%), Gaps = 29/248 (11%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 61 S +T + PTP + + P V S ++ P + P SP E+ Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP-PAVTSP--SPKEA 1613 Query: 62 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121 P+ P+ TP PSP P + + P T ++++ S ++ + G + + Sbjct: 1614 -PTPPAVTP-PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671 Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181 P + ++ L P PE S+ + APT T + +S Sbjct: 1672 LPAKKGPTALKEVLVAPAPE---STPIITAPTRKGPQT---------------KKSSATS 1713 Query: 182 PELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTI 241 P + P P+ + S P++ T P LL P D S ++ ++ + +APP Sbjct: 1714 PPICPDPSAKNGSKGPLS-TVAPAPLL-----PVQKDSSKTAKGKDASHSPKGPLAPPES 1767 Query: 242 PSATPATA 249 ++TP TA Sbjct: 1768 KASTPLTA 1775 Score = 41.2 bits (95), Expect = 0.007 Identities = 87/364 (23%), Positives = 134/364 (36%), Gaps = 89/364 (24%) Query: 46 ADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQM--SVEE 103 AD G+ + + ++ SP + L P + P + T+TT+ + + E Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP------VKEGTLTTLPLVPTASE 706 Query: 104 STPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSP-----------LQ 150 + P++ SP+ T PLA +L E+ S P P + +P Sbjct: 707 NCPVAP--------SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758 Query: 151 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ----PEE 206 A P+AS E P+ED +S + S SP+ ++ + Q P + Sbjct: 759 ALAPVASSPKEC-------PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811 Query: 207 LLNGAPSPPAVDLS-PVSEPE-----------EQAKEVTASMAPPTIPSATPATAPSATS 254 + P P +LS PVS E + +K+ A+ PT PS A PSA + Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871 Query: 255 PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPA--NLSQNLEAAAATQVA 312 P S KG LPP+ TP P+ NL E A Sbjct: 872 PL-----------------------SPKG--VTLPPKETPTPSVVNLPFPKEGP-----A 901 Query: 313 VSVPKRRRKIKELNKKEAVGDLLDAFK--EANPAVPEVENQPPAGSNPGPESEGSGVPPR 370 PK+ + + A K A+P+ P+ PPA + P P +G P Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSP--KGGPATPS 958 Query: 371 PEEA 374 P+ A Sbjct: 959 PKWA 962 Score = 32.3 bits (72), Expect = 3.3 Identities = 56/223 (25%), Positives = 78/223 (34%), Gaps = 51/223 (22%) Query: 21 PQANGETPQVA-----VIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV 75 P++ TP A V+ +P+ S A SP S P +PSP P+ P Sbjct: 1765 PESKASTPLTAAAFEKVLPKPESASVSAA-----------PSPPVSLPLAPSPVPTLPPK 1813 Query: 76 LE-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT 134 + S P L VL P + +E P+ + PEP P V V Sbjct: 1814 QQFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQSVLVN 1861 Query: 135 LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES 194 + P S+ + PTP A V + S+ ES PEL E Sbjct: 1862 MPTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL--------EE 1903 Query: 195 PVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 237 T Q +L A +D PVS+ ++ E A A Sbjct: 1904 QDSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 73.6 bits (179), Expect = 1e-12 Identities = 70/253 (27%), Positives = 101/253 (39%), Gaps = 18/253 (7%) Query: 12 PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP- 70 P +T L P + +TP ++ P + P +P P P+P P Sbjct: 511 PLETQSSLAPPSL-QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569 Query: 71 --SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI 128 PSP+ P E ++ + P + S P+ P P P A P Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALA-----SPPLQGLPSPPLSPLATPPPQAPPX 624 Query: 129 LEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH---EPNGMVPSEDLEPEVESSPELA 185 L + + P P + SPL P+P A + + +H P PS ++ SP A Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPP-A 681 Query: 186 PPPACPSESPVPIAPTAQPEELLNGAPSPPAVD-LSPVSEPEEQAKEVTAS--MAPPTIP 242 PP PS +P AP + L PSPPA +SP + P QA A+ + P P Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741 Query: 243 SATPATAPSATSP 255 A+P +PSAT P Sbjct: 742 PASPPMSPSATPP 754 Score = 72.0 bits (175), Expect = 4e-12 Identities = 75/252 (29%), Positives = 104/252 (41%), Gaps = 28/252 (11%) Query: 8 STPTPPQTGGGLEPQANG-ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSP 66 +TP P P G +P ++ + P ++ + P L P SP S P SP Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL--PPLQAPP-SPPASPPLSP 644 Query: 67 SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAE 126 TPSP A S P S S P+S P S P LA Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAA 701 Query: 127 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP 186 P L+V + P S ++ P QAP PLA+ +++ PS P + SP P Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP------PSPPASPPM--SPSATP 753 Query: 187 PPACPSESPVPIAPTAQPEELLNGAPSPPA-VDLSPVSEPEEQAKEVTAS---MAPPTIP 242 PP P P+ AP Q PSPPA + +SP+++P QA A+ A P+ P Sbjct: 754 PPRVP---PLLAAPPLQVP------PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804 Query: 243 SATPATAPSATS 254 ++ P AP + S Sbjct: 805 ASFPGQAPFSPS 816 Score = 64.7 bits (156), Expect = 6e-10 Identities = 69/251 (27%), Positives = 92/251 (36%), Gaps = 43/251 (17%) Query: 48 RPGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIPGDTMTTIQMS 100 RP P+ P + S P+SP S SP + P S P L LS +S Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505 Query: 101 VEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPESEFSSSPLQA 151 P+ ++ P L P L P LE +L S P+ + P A Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565 Query: 152 PTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVPIAPTAQPEEL 207 P PL + + P PS P ++ P LA PP P SP+ P P L Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 208 ----LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTASMAPPTIPSA 244 L PSPPA LSP++ P QA V A +PP P Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685 Query: 245 TPATAPSATSP 255 +P+ P + +P Sbjct: 686 SPSATPPSQAP 696 Score = 60.8 bits (146), Expect = 9e-09 Identities = 64/221 (28%), Positives = 89/221 (40%), Gaps = 27/221 (12%) Query: 58 PSESQPS--SPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 115 P E+Q S PS P+ + P E ++ P T + + TP P Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP---PCPAPC 567 Query: 116 RLSPEPTPLAEPILEVEVTLSKPVPESE--FSSSPLQA-PTPLASHTVEIHEPNGMVPSE 172 L P+PL P E +++ P P++ +S PLQ P+P S + P P Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS---PLATPPPQAPPX 624 Query: 173 DLEPEVESSPEL-APPPACPSESPVPIAPTAQPEELLNGA----PSPPA-VDLSPVSEPE 226 P +++ P A PP P +P P AP A LL PSPP SP + P Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684 Query: 227 EQAKEVTASMAPPTI----------PSATPATAPSATSPAQ 257 S APP++ P A+P +PSAT P Q Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725 Score = 52.0 bits (123), Expect = 4e-06 Identities = 68/282 (24%), Positives = 98/282 (34%), Gaps = 57/282 (20%) Query: 1 MSGARTASTPTP-------PQTGGGLEPQANGETPQVAVIVRPDDRS--QGAIIADRPGL 51 +S A ST P P GGGL+ RP RS A P Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQ--------------RPASRSLSSSATPLSSPAR 254 Query: 52 PGPEHSPSESQPSSPS-PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 110 GP + P+ PS P P L P P + P + S+P++ Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRP---PQVT----PPRKDAAPALGPLSSSPLATP 307 Query: 111 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP 170 + + P P P + P+P + S PL P PLA + +P Sbjct: 308 SPSGTKARPVPPP---------DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358 Query: 171 SEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL----LNGAPSPPAVD----LSPV 222 S P ++ P + PP S I P P L L PSP A+ + + Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 223 SEPEEQA---------KEVTASMAPPTIPSATPATAPSATSP 255 P QA ++ AS+ P+ P++TP +P +P Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460 Score = 44.3 bits (103), Expect = 8e-04 Identities = 72/300 (24%), Positives = 94/300 (31%), Gaps = 54/300 (18%) Query: 57 SPSESQPSSPSPTPSP-----------------------SPVLEPGSEPNLAVLSIPGDT 93 SP S P SPS TP P SP+ +P + A+ + P Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799 Query: 94 MTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP- 152 + + S P S P P P A P+L + VP S +S LQAP Sbjct: 800 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPR 856 Query: 153 -TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 208 P + P + P P S L+ P S + T+ PEE L Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-L 911 Query: 209 NGAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEE 260 G S P SP + E A A P P A P P AT P + Sbjct: 912 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971 Query: 261 MEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320 + E E E+ + G P P A A + PK+ R Sbjct: 972 LCTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021 Score = 42.4 bits (98), Expect = 0.003 Identities = 71/302 (23%), Positives = 112/302 (37%), Gaps = 56/302 (18%) Query: 7 ASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ-PSS 65 +S+ TP + P A G A +P + A+ + P + +P+ SS Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302 Query: 66 PSPTPSPSPV-LEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR---ETGEPYRLSPEP 121 P TPSPS P P+ A +P T+ S +TP+ P L P Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPA----TLPPSPPLATPLPLAPPSPSAPPSLQTLP 358 Query: 122 TPLAEPILEVEVTLSKP---------------VPESEFSSSPLQAPTPLASHTVE----- 161 +P A P + +++ P VP S S S P+PLA +++ Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 162 -------IHEPNGMVPSE-DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS 213 H M P + S P PP + P ++P+ + + + L+ A S Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478 Query: 214 P--------PAVDLSPVSEPEEQAK---------EVTASMAPPTI--PSATPATAPSATS 254 P P LS ++ QA E +S+APP++ P A+ T P Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538 Query: 255 PA 256 P+ Sbjct: 539 PS 540 Score = 31.6 bits (70), Expect = 5.6 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 14/151 (9%) Query: 10 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLP-GPEHSPSESQPSSPSP 68 P+PP + G P + + ++ + P ++ + A +P P SP+ P P P Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP-P 859 Query: 69 TPSPSP---------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR-ETGEPYRLS 118 TP P L PG P + P T++ ++ S+ S E Y Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPS--RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917 Query: 119 PEPTPLAEPILEVEVTLSKPVPESEFSSSPL 149 PE A P + E+ P S + PL Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPL 948 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 72.0 bits (175), Expect = 4e-12 Identities = 60/257 (23%), Positives = 92/257 (35%), Gaps = 17/257 (6%) Query: 8 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67 +TP+PP T P +P ++ P + + P P SP + ++P Sbjct: 1436 TTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495 Query: 68 PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP---TPL 124 PT +PSP P ++ P T TT+ + S P + T P +P P TP+ Sbjct: 1496 PTTTPSP-------PTTTPITPPAST-TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547 Query: 125 AEPILEVEV---TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181 P + T P P + + P P+P + T P P ++ Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607 Query: 182 PELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 238 PPP P PI P L PSPP + + T + +P Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667 Query: 239 PTIPSATPATAPSATSP 255 P + TP + +SP Sbjct: 1668 PITTTTTPPPTTTPSSP 1684 Score = 69.3 bits (168), Expect = 2e-11 Identities = 64/246 (26%), Positives = 85/246 (34%), Gaps = 34/246 (13%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65 T +T TPP T P TP + P P SP + ++ Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1571 Query: 66 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125 P PT +PSP P S P T TT + S P + T P +P P P Sbjct: 1572 PPPTTTPSP-------PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTT 1623 Query: 126 EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185 PI T + P P + S P TP + T P P + Sbjct: 1624 TPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPS--------PPTTTTPSPPITTTTT 1674 Query: 186 PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT 245 PPP SP+ P+ P PSP SP++ + T S P T+ + + Sbjct: 1675 PPPTTTPSSPITTTPS--PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732 Query: 246 PATAPS 251 P T PS Sbjct: 1733 PTTTPS 1738 Score = 62.4 bits (150), Expect = 3e-09 Identities = 65/260 (25%), Positives = 87/260 (33%), Gaps = 19/260 (7%) Query: 44 IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103 I P P P+ + P+ TPSP P + P S P T TT + Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454 Query: 104 STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 163 S PIS T P +P P P + P P + +++P TP T I Sbjct: 1455 SPPISTTTTPPPTTTPSP-----PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509 Query: 164 EPNGMVPSEDLEPEVESSP----ELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPA 216 P + L P SP PPP P PI P L PSPP Sbjct: 1510 PP---ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566 Query: 217 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 276 + + T + +PPTI + TP P T+P+ + Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPPTTTTTTPPPTTTPSPPTT 1623 Query: 277 EAESEKGGEELLPPESTPIP 296 + LPP +TP P Sbjct: 1624 TPITPPTSTTTLPPTTTPSP 1643 Score = 55.1 bits (131), Expect = 5e-07 Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 20/218 (9%) Query: 8 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67 +TP+PP T P +P P I P SP + ++P Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITTTTPPPTTTPSPPTTTTTTPP 1613 Query: 68 PTPSPSP-----VLEPGSE---PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 119 PT +PSP + P S P S P T TT + S P + P + Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673 Query: 120 EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 179 P P P + T P P + ++P TP + T + PS Sbjct: 1674 TPPPTTTPSSPITTT---PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730 Query: 180 SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 217 SP P P + + +P T+ P L P PP++ Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSP---LTTTPLPPSI 1765 Score = 51.2 bits (121), Expect = 7e-06 Identities = 67/268 (25%), Positives = 95/268 (35%), Gaps = 43/268 (16%) Query: 6 TASTPTPPQTGGGLEPQANGETP-QVAVIVRPDDRSQGA-------IIADRPGLPGPEHS 57 T TPTP TG Q TP V P G I P P + Sbjct: 4067 TTVTPTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122 Query: 58 PSESQPSSP-------SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 110 +++ ++P +PTP+P+ P + P ++ T T +TPI+ Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTT 4181 Query: 111 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP 170 T ++P PTP T + P+ E S+ P ++ TP S + Sbjct: 4182 T----TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS--------- 4228 Query: 171 SEDLEPEVESSPELAP-PPACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEE 227 P ES+ L+ PPA S P + P G PP+ SP P Sbjct: 4229 ----SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284 Query: 228 QAKEVTASMAPPTIPSATPATAPSATSP 255 T S + PT PS T SA +P Sbjct: 4285 GT--TTGSSSAPT-PSTVQTTTTSAWTP 4309 Score = 50.4 bits (119), Expect = 1e-05 Identities = 57/214 (26%), Positives = 74/214 (34%), Gaps = 34/214 (15%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65 T +T TPP T P TP + P P SP + ++ Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1650 Query: 66 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125 P PT +PSP P S P T TT + S+PI+ P P+P Sbjct: 1651 PPPTTTPSP-------PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703 Query: 126 EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185 P + T + P S + SP S T P + + L P SSP L Sbjct: 1704 TPSSPITTTTT---PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT--LPPTTTSSP-LT 1757 Query: 186 PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219 P PS +P PT P P+ P V L Sbjct: 1758 TTPLPPSITP----PTFSP--FSTTTPTTPCVPL 1785 Score = 35.0 bits (79), Expect = 0.51 Identities = 62/280 (22%), Positives = 94/280 (33%), Gaps = 54/280 (19%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65 T TPTP TG P + T +A + + P PE S ++ S+ Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN--------------PPPESSTPQTSRST 4227 Query: 66 PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125 SP + +L P MT+ + P + G + LSP P+ Sbjct: 4228 SSPLTESTTLLSTLP---------PAIEMTSTAPPSTPTAPTTTSGG--HTLSPPPSTTT 4276 Query: 126 EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185 P P + SS P+ + + T P P+ P + + L Sbjct: 4277 SPP-------GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT---PTPLSTPSIIRTTGLR 4326 Query: 186 PPPA----CPSESPVPIAPTAQPEELLNGAPSPPAV----DLSPVSE------PEEQAKE 231 P P+ C + AP EE+ NG LS E P + Sbjct: 4327 PYPSSVLICCVLNDTYYAPG---EEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 4383 Query: 232 VTASMAPPTI--PSATPATAPSATSPAQEEEMEEEEEEEE 269 T S + PT PS+TP+ T P + + + +E E Sbjct: 4384 PTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENE 4423 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 72.0 bits (175), Expect = 4e-12 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%) Query: 27 TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 86 +P ++ + P ++ A+ P L P SP S P SP TPSP A Sbjct: 383 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 439 Query: 87 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 146 S P S S P+S P S P LA P L+V + P S ++ Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 496 Query: 147 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 200 P QAP PLA+ +++ +P P P +++ P +PP + P ++P +P++P Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 554 Query: 201 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 241 A P LL PSPPA +P + +T ++A PP Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614 Query: 242 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 297 PS +P++ S A EE G +GG PP + PA Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 669 Query: 298 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 355 S+ A + A P + + + + + A PA ++ P G Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729 Query: 356 SNPGPESEGSG 366 ++ G + G+G Sbjct: 730 TSGGKAAAGAG 740 Score = 51.2 bits (121), Expect = 7e-06 Identities = 66/272 (24%), Positives = 91/272 (33%), Gaps = 33/272 (12%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS---PSESQ 62 T TP+P P+ A RP RP GP S SE Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARP-----------RPPTEGPRKSVSSASEHS 216 Query: 63 PSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121 + PSP P G + P LS +++ S + R P + P+ Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276 Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP-SEDLEPEVES 180 P SSSPL P+P A+ + P S L ++ + Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336 Query: 181 SPELAPPP--ACPSESPVPIAPTAQPEELLNGAPSP---------PAVDLSPVSEPEEQA 229 LAPP A PS +P P P + SP P+ LSP++ P QA Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396 Query: 230 KE------VTASMAPPTIPSATPATAPSATSP 255 + A +PP P +P PS +P Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAP 428 Score = 47.8 bits (112), Expect = 8e-05 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%) Query: 8 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67 S P P P A+ P V+ P ++ ++ A P L P SP S P SPS Sbjct: 441 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 494 Query: 68 PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 117 TP +P P + +P + A+ + P + + S P S P Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554 Query: 118 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 172 P P A P+L + VP S +S LQAP P + P + P Sbjct: 555 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611 Query: 173 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 230 P S L+ P S + T+ PEE L G S P SP + E A Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 666 Query: 231 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 284 A P P A P P AT P + + E E E+ + G Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 725 Query: 285 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320 P P A A + PK+ R Sbjct: 726 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 752 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 72.0 bits (175), Expect = 4e-12 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%) Query: 27 TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 86 +P ++ + P ++ A+ P L P SP S P SP TPSP A Sbjct: 344 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 400 Query: 87 LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 146 S P S S P+S P S P LA P L+V + P S ++ Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 457 Query: 147 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 200 P QAP PLA+ +++ +P P P +++ P +PP + P ++P +P++P Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 515 Query: 201 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 241 A P LL PSPPA +P + +T ++A PP Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 Query: 242 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 297 PS +P++ S A EE G +GG PP + PA Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 630 Query: 298 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 355 S+ A + A P + + + + + A PA ++ P G Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690 Query: 356 SNPGPESEGSG 366 ++ G + G+G Sbjct: 691 TSGGKAAAGAG 701 Score = 51.2 bits (121), Expect = 7e-06 Identities = 65/261 (24%), Positives = 90/261 (34%), Gaps = 41/261 (15%) Query: 6 TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS---PSESQ 62 T TP+P P+ A RP RP GP S SE Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARP-----------RPPTEGPRKSVSSASEHS 207 Query: 63 PSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121 + PSP P G + P LS +++ S + R P + P+ Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267 Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181 P SSSPL P+P A PS P +++ Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP------------PSPSAPPSLQTL 315 Query: 182 PELAPPPACPSESPVPI-APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE------VTA 234 P +PP PS++ + +PT Q PSPP LSP++ P QA + A Sbjct: 316 P--SPPATPPSQATTSLGSPTLQATHSF--LPSPP---LSPLATPPPQAPPALALPPLQA 368 Query: 235 SMAPPTIPSATPATAPSATSP 255 +PP P +P PS +P Sbjct: 369 PPSPPASPPLSPLATPSPQAP 389 Score = 47.8 bits (112), Expect = 8e-05 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%) Query: 8 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67 S P P P A+ P V+ P ++ ++ A P L P SP S P SPS Sbjct: 402 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 455 Query: 68 PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 117 TP +P P + +P + A+ + P + + S P S P Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515 Query: 118 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 172 P P A P+L + VP S +S LQAP P + P + P Sbjct: 516 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 Query: 173 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 230 P S L+ P S + T+ PEE L G S P SP + E A Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 627 Query: 231 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 284 A P P A P P AT P + + E E E+ + G Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 686 Query: 285 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320 P P A A + PK+ R Sbjct: 687 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 713 Score = 40.8 bits (94), Expect = 0.009 Identities = 63/264 (23%), Positives = 93/264 (35%), Gaps = 53/264 (20%) Query: 42 GAIIADRPGLPGPEHSP-----SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT-MT 95 GA I + GP + + + P+ SP PV PG + PG Sbjct: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT---TRPGPLGQK 123 Query: 96 TIQMSVEESTPISRETGEPYRLSPE---------PTP-LAEPILE-------VEVTLSKP 138 +++S EE+ + T P R + PTP P + EV L +P Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183 Query: 139 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV--------------ESSPEL 184 P + P + P S E H P+ P ++P Sbjct: 184 APSAR-PRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241 Query: 185 APPPACPSESPVPIAPT--AQP-----EELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 237 +P + PS P AP +QP + L +PP D +P P + T S + Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 Query: 238 PPTIPSATPA----TAPSATSPAQ 257 P PSA P+ +P AT P+Q Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQ 325 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 71.6 bits (174), Expect = 5e-12 Identities = 99/383 (25%), Positives = 140/383 (36%), Gaps = 69/383 (18%) Query: 11 TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGP---EHSPS-----ESQ 62 +PP+ G + P + G + + +P PGP E P + + Sbjct: 373 SPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427 Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122 P +P P+L P P + LS P E +P S E RLSP P Sbjct: 428 PQLEAPLNEEMPLLPP---PEESPLSPP-----------PEESPTSPPP-EASRLSPPPE 472 Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTVEIHEPNGMVPSEDLEPEVES 180 L L + LS+P+ ES S P ++P P S E + + P E+ P Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532 Query: 181 SPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 239 L+PPP A P P +P + P E L +P P A LSP PEE + M+PP Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP--PPEE------SPMSPP 584 Query: 240 TIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 295 P +P + P S P +E + EE S PPE +P+ Sbjct: 585 --PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP-------PPEDSPM 635 Query: 296 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQP--- 352 + + +S P ++ L V L E +P P E P Sbjct: 636 ---------SPPPEESPMSPPPEVSRLSPL----PVVSRLSPPPEESPLSPPPEESPTSP 682 Query: 353 -PAGSNPGPESEGSGVPPRPEEA 374 P S P E S P PE++ Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDS 705 Score = 70.5 bits (171), Expect = 1e-11 Identities = 80/345 (23%), Positives = 128/345 (37%), Gaps = 37/345 (10%) Query: 55 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT--TIQMSVEESTPISRETG 112 +H+P S+ S P P +P+ EP+ ++ G M +E P+ E Sbjct: 364 QHTPVCSRFSPPEPGDTPT------DEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK 417 Query: 113 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 172 + + P E L E+ L P ES S P ++PT + P +P+ Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477 Query: 173 DL---------------EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 217 L P E SP L+PPP SP+ +P + PEE +P PA+ Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESP-LSPPPESSPFSPLEESPLSPPEE----SPPSPAL 532 Query: 218 DLSPVSEPEEQA------KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271 + +P+S P E + +E S P +P++ P A + P +E M EE Sbjct: 533 E-TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591 Query: 272 AGEAGEAESEKGGEELL--PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKE 329 E L PPE +P+ + + +S P + + Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651 Query: 330 AVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEA 374 + L + + P + PP S P E S + P PE++ Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696 Score = 69.7 bits (169), Expect = 2e-11 Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%) Query: 9 TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 64 T P+ G L+ +A P V+ + + + + + P LP PE S P E P+ Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458 Query: 65 SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 113 SP P SP P P S P LS P + E ES+P S Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518 Query: 114 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 166 P LSP P LE ++ LS P ES S P + PT + P Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576 Query: 167 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 224 P + P E SP PP A P +P + P E +P P A LSP E Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633 Query: 225 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 282 P E + PP + +P S SP EE EE EA Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691 Query: 283 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 342 PPE +P + + +S+P + L ++ + + + Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744 Query: 343 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 373 P E P P + P++E + P+PEE Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776 Score = 65.5 bits (158), Expect = 4e-10 Identities = 87/304 (28%), Positives = 118/304 (38%), Gaps = 33/304 (10%) Query: 9 TPTPPQTGGGLEPQANGETPQVAVIVRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSP 66 +P P L E+P + + P RS+G ++ RP P P E S Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764 Query: 67 SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP------ISRETGEPYRLSPE 120 + P SP E EP L ++P + + Q +P +S +T EP+ LSP Sbjct: 765 AEEPHLSPQPE---EPCLC--AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPV 818 Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180 P EP L + S P+SE P +P P SH E + P + PE Sbjct: 819 PE---EPCLSPQPEESHLSPQSE---EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872 Query: 181 ---SPE---LAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTA 234 +PE L PPP PS SP+ P +P P + LSP EP + + Sbjct: 873 QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP 932 Query: 235 SMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 294 PP + A AP A SP E E G G++ + ES L P S P Sbjct: 933 DPLPPPLSPIITAAAPPALSPLGELEY------PFGAKGDS-DPESPLAAPILETPISPP 985 Query: 295 IPAN 298 AN Sbjct: 986 PEAN 989 Score = 63.5 bits (153), Expect = 1e-09 Identities = 68/298 (22%), Positives = 108/298 (36%), Gaps = 31/298 (10%) Query: 96 TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPL 155 TI+ E+ TP+ P P TP EP +P S P + P PL Sbjct: 357 TIRSVAEQHTPVCSRFSPP---EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKE-PGPL 412 Query: 156 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 215 + + + + P E P L PP P P +PT+ P E +P P Sbjct: 413 QCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE 472 Query: 216 AVDLSPVSEPEEQAKEVTAS-MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 274 + SP+ E ++ + S ++PP P +P + P +SP E EE Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPP--PEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530 Query: 275 AGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI------------ 322 A E PPE++P+ ++ + ++ S P ++ Sbjct: 531 ALETPLSP------PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584 Query: 323 ---KELNKKEAVGDLLDAFKEANPAVPEVE---NQPPAGSNPGPESEGSGVPPRPEEA 374 ++ L F+E+ + P E + PP S P E S + P PEE+ Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642 Score = 55.8 bits (133), Expect = 3e-07 Identities = 100/401 (24%), Positives = 142/401 (35%), Gaps = 52/401 (12%) Query: 9 TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP---------- 58 +P P ++ P+++ +P + P + S + + P P PE SP Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554 Query: 59 ---SESQPSSP-------SPTP-----SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103 E P+SP SP P SP P P S P A P + + EE Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614 Query: 104 STPISRETGEPYRLSPEP--TPLAEPILEVEVTLSKPVPESEFSSSPLQA---PTPLASH 158 S P+S E RLSP P +P++ P E +S P S S P+ + P P S Sbjct: 615 S-PLSPPP-EASRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670 Query: 159 TVEIHEPNGMVPSED---LEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 215 E + P + L P E SP PP P+ P PE+ L P Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--------PEDSLMSLPLEE 722 Query: 216 AVDLSPVSEPEEQAKEVTASMAP-PTIPSATPATAPSATSPAQEEEMEEEEEEEE--GEA 272 + L EP+ + ++P P P +P SP EE + EE Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782 Query: 273 GEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 332 E + G L P P +LS E + V + + ++ Sbjct: 783 PEEPHLSPQAEGPHLSP---QPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE 839 Query: 333 DLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 373 L E + PE+E +PP P E G P PEE Sbjct: 840 PCLSPRPEESHLSPELE-KPPLSPRPEKPPEEPGQCPAPEE 879 Score = 48.1 bits (113), Expect = 6e-05 Identities = 60/266 (22%), Positives = 92/266 (34%), Gaps = 37/266 (13%) Query: 6 TASTPTPPQTGGGLEPQANG-----ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60 TA + Q G G +A+ P V++ +P +Q + +P L P + + Sbjct: 4110 TAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTG 4169 Query: 61 SQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 119 QP P P PVL+ G P + ++ G +Q + ++ + LSP Sbjct: 4170 PQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR-------HLSP 4216 Query: 120 EPTPLAEPIL-------EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP-NGMVPS 171 + + +L V + P E +SPLQ P G + Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276 Query: 172 EDLEPEVESSPELAPPPACPSESPV--PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 229 P + P L PP S PV P+ PT PS P P P + Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--------PPSSPQEPKRPSQLPSPSS 4328 Query: 230 KEVTASMAPPTIPSATPATAPSATSP 255 + T + PPT P P+ P Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPP 4354 Score = 45.1 bits (105), Expect = 5e-04 Identities = 101/416 (24%), Positives = 135/416 (32%), Gaps = 108/416 (25%) Query: 10 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69 P P TG +P P + RP G PG P QPS+P P Sbjct: 2198 PYPSPTGAPAQP------PMLGASSRPGAGQPGEFHTTPPGTP-------RHQPSTPDPF 2244 Query: 70 PSPS-PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI 128 P P L+ NLAV PG + EP LSP P + Sbjct: 2245 LKPRCPSLD-----NLAVPESPGVG--------------GGKASEPL-LSPPPFGESRKA 2284 Query: 129 LEV---EVTLSKP---VPESEFSSSP----------LQAP-------TPLASHTVEIHEP 165 LEV E+ S P P F SP L+ P TP AS VE P Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ-VEPQSP 2343 Query: 166 N-GMVPSED-----LEPEVESSPEL----------APPPACPSESPVP------IAPTAQ 203 G+ P E L P S P++ A PP P P P + P + Sbjct: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL 2403 Query: 204 PEELLNGAPSPP---AVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-- 258 P + + P+ P + SP++ A+ S P S P + P + +++ Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463 Query: 259 ----EEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES------TPIPANLSQNLEAAAA 308 + + E +AG GG P +P+ N + Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG 2523 Query: 309 TQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSN----PGP 360 T V P R +AVG+ P VP+ PP G N PGP Sbjct: 2524 TGAFVGTPSPMR----FTFPQAVGE-----PSLKPPVPQPGLPPPHGINSHFGPGP 2570 Score = 42.0 bits (97), Expect = 0.004 Identities = 81/343 (23%), Positives = 119/343 (34%), Gaps = 59/343 (17%) Query: 3 GARTASTPTPPQTGGGLE------PQANGETPQVA--VIVRPDDRS-----QGAIIADRP 49 GA+ S P P LE P+AN P+ +I+ P S ++ P Sbjct: 962 GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021 Query: 50 GLPGP--EHS--PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST 105 P +HS P S PS SP P V P S P V+ + D +M E+ + Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS-PIGKVVGV-SDEAELHEMETEKVS 1079 Query: 106 PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP 165 EP SP P+P+ + + P P + S + PL +P Sbjct: 1080 EPECPALEPSATSPLPSPMGD----LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP 1135 Query: 166 NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA------------QPEELLNGAPS 213 L E++ SP L P +P+ + P Q E AP+ Sbjct: 1136 EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPT 1195 Query: 214 PPAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAPSAT---------SPAQEE- 259 PP + S + + AS + P + S P S + SPA++E Sbjct: 1196 PPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEG 1255 Query: 260 ----------EMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 292 E ++ + G A G+AE EKG P S Sbjct: 1256 SLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARS 1298 Score = 38.9 bits (89), Expect = 0.035 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 21/85 (24%) Query: 185 APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV-TASMAPPTIPS 243 APPP PS P P+AP SP S P E E+ T +A P +PS Sbjct: 4908 APPPEEPSPPPSPLAP-------------------SPASPPTEPLVELPTEPLAEPPVPS 4948 Query: 244 ATP-ATAPSATSPAQEEEMEEEEEE 267 P A++P + P EE E+ Sbjct: 4949 PLPLASSPESARPKPRARPPEEGED 4973 Score = 37.7 bits (86), Expect = 0.078 Identities = 95/415 (22%), Positives = 137/415 (33%), Gaps = 86/415 (20%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 60 SG T STPT P T G + +G + + R + D G + P L + P+ Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031 Query: 61 SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 105 Q P S P +P L+ + A Q++ + Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091 Query: 106 PISRETGEP---YRLSPEPTPLAEPILEVEVTL------------------------SKP 138 I+R+T P R+ P+P L P T+ S P Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP 2151 Query: 139 VPESE---FSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP 195 P+S F P Q P + S +P G+ P+ LEP ++P PP P+ +P Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQ-----DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206 Query: 196 VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255 AQP L GA S P +P E T P TP PS P Sbjct: 2207 ------AQPPML--GASSRPG-----AGQPGEF----------HTTPPGTPRHQPSTPDP 2243 Query: 256 AQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSV 315 + + E+ G K E LL +P P S+ ++ S Sbjct: 2244 FLKPRCPSLDNLAVPESPGVG---GGKASEPLL----SPPPFGESRKALEVKKEELGASS 2296 Query: 316 PKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 370 P + G L + P V + P A S P+S G G+ P+ Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350 Score = 36.2 bits (82), Expect = 0.23 Identities = 67/307 (21%), Positives = 100/307 (32%), Gaps = 59/307 (19%) Query: 10 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG-AIIADRPGLPGPEHSPSESQPSSPSP 68 P PP++ L P++ P V P +S + + RP L PS P SP Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSP 2447 Query: 69 TPSPSPVLEPGSEPNLAVL------------------------------SIPGDTMTTIQ 98 P P P S A L ++P + Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507 Query: 99 MSVEESTPIS--RETGE-PYRLSPEPTPLAEPILEVEVTLSKPVPE----------SEFS 145 V P + R G + +P P P E +L PVP+ S F Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567 Query: 146 SSPLQAPTPLASHTVEI--HEPNG--MVPSEDLEPEVESSPELAPPPACPSESPVPIAPT 201 P ++TV P+G + PS E L PP P P AP Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP-----PPAPD 2622 Query: 202 AQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEM 261 L +GA + SPV + E+ + +S+A +P T S + E+ Sbjct: 2623 GSLPYLSHGASQRSGIT-SPVEKREDPGTGMGSSLATAELPG----TQDPGMSGLSQTEL 2677 Query: 262 EEEEEEE 268 E++ + + Sbjct: 2678 EKQRQRQ 2684 Score = 35.8 bits (81), Expect = 0.30 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%) Query: 50 GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 109 G PGP+ P + + P P P PG+ VL Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303 Query: 110 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 169 P +P P+ EP P Q P+P + E P Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337 Query: 170 PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 229 P+ P+ + P L PPP S + +A T + L P P +L+ +PE+ Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391 Query: 230 KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 264 +S+ P + P A+ + ++E EE Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422 Score = 34.3 bits (77), Expect = 0.86 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 14/100 (14%) Query: 151 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPE---LAPPPACPSESP---VPIAPTAQP 204 AP P H+ + N V P E SP LAP PA P P +P P A+P Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944 Query: 205 EELLNGAPSPPAVDLSPVS---EPEEQAKEVTASMAPPTI 241 PSP + SP S +P + E PP + Sbjct: 4945 P-----VPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979 Score = 32.7 bits (73), Expect = 2.5 Identities = 93/419 (22%), Positives = 145/419 (34%), Gaps = 72/419 (17%) Query: 8 STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67 S+P Q G P A G + +++ P + G I+ GP PS+ + S P Sbjct: 2725 SSPAFEQLSRGQTPFA-GTQDKSSLVGLPPSKLSGPIL-------GPGSFPSDDRLSRPP 2776 Query: 68 PTPSPSPV------LEPGSEPNLAVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSPE 120 P +PS + L GS+ PG + Q + + + T + +S Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSAR 2836 Query: 121 ----PTP------LAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE-PNGMV 169 P P L P+ + L P P+ P A H G+ Sbjct: 2837 FPSTPGPELGRQALGSPLAGISTRLPGP-------GEPVPGPAGPAQFIELRHNVQKGLG 2889 Query: 170 PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-----SPPAVDLSPVSE 224 P P P P SE P +AP ++G P +PPA +L+ Sbjct: 2890 PGG--TPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLH 2947 Query: 225 PEEQAKEVTASMAPPTI---PSAT------PATAPSATSPAQEEEMEEE-------EEEE 268 P K T + PS+T P + P ++ E++++ E++E Sbjct: 2948 PTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDE 3007 Query: 269 E----GEAGEAGEAESEKGGEELLPPESTPIPANLS-QNLEAAAATQVAVSVPKRR---- 319 E G + + + E G E L + L+ + A T + ++ Sbjct: 3008 ELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFN 3067 Query: 320 ---RKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA--GSNPGPESEGSGVPPRPEE 373 R ++ N+K LL E P PE E PPA S P S V P+ EE Sbjct: 3068 EHLRLVESANEKAEREALLRGV-EPGPLGPE-ERPPPAADASEPRLASVLPEVKPKVEE 3124 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 70.9 bits (172), Expect = 8e-12 Identities = 95/390 (24%), Positives = 133/390 (34%), Gaps = 63/390 (16%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRP--------GLPG 53 + A STP P + P T A + P++ + A P +P Sbjct: 989 TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPT 1048 Query: 54 PEHS-------PSESQPSSPS---PTP----SPSPVLEPGSEPNLAVLSIPGDTMTTIQM 99 PE P+ +P+SP+ PTP SP+ + EP ++P T Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT--- 1105 Query: 100 SVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159 S + P E P P P A P V P PE +P PTP S + Sbjct: 1106 SPAAAVPTPEEPASPAAAVPTPEEPASPAAAV------PTPEEPAFPAP-AVPTPEESAS 1158 Query: 160 VEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 218 + P PE +SP A P PA + +A +P P+P A+ Sbjct: 1159 AAVAVPT---------PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM- 1208 Query: 219 LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEA 278 ++ + E A V S P ++ +A + TSPA + EE A Sbjct: 1209 VATLEEFTSPAASVPTSEEPASLAAAV-SNPEEPTSPA--AAVPTLEEPTSSAAAVLTPE 1265 Query: 279 ESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 338 E + PE PA NLE A+ AV P+ + A Sbjct: 1266 ELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE-----------------VAAI 1308 Query: 339 KEANPAVPEVENQPPAGSNPGPESEGSGVP 368 A+ PEV P A P E GVP Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338 Score = 60.8 bits (146), Expect = 9e-09 Identities = 86/333 (25%), Positives = 110/333 (33%), Gaps = 38/333 (11%) Query: 58 PSESQPSSPSPTPSPSPVLEPGSEPNLAVL--SIPGDTMTTIQMSVEESTPISRETGEPY 115 P + +P +P+ + EP+ A + S P + + P S P Sbjct: 963 PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT 1022 Query: 116 RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTVEIHEPNGMVPSEDL 174 P A P E + + VP E +SP A PTP E P VP+ Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVPT--- 1074 Query: 175 EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGA-----PSPPAVDLSPVSEPEEQA 229 PE +SP A P P E P A PEE + A P PA + V PEE A Sbjct: 1075 -PEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131 Query: 230 KEVTASMAP--PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKG---- 283 A P P P+ T + S A EE E+ S Sbjct: 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT 1191 Query: 284 -GEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI----------KELNKKEAVG 332 E P S P PA + LE T A SVP + + AV Sbjct: 1192 LEEPTSPAASVPTPAAMVATLE--EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249 Query: 333 DLLDAFKEANPAVPEVENQPPAGSNPGPESEGS 365 L + A + E PA S P PE S Sbjct: 1250 TLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282 Score = 53.9 bits (128), Expect = 1e-06 Identities = 64/290 (22%), Positives = 103/290 (35%), Gaps = 27/290 (9%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS--PS 59 S A TP P + P T A + P++ + A P P + P+ Sbjct: 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126 Query: 60 ESQPSSPS---PTPS----PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETG 112 +P+SP+ PTP P+P + E A +++P + + + S Sbjct: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186 Query: 113 EPYRLSPEPTPLAEPI---------LEVEVTLSKPVPESEFSSSPLQA------PTPLAS 157 EPT A + LE + + VP SE +S A PT A+ Sbjct: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA 1246 Query: 158 HTVEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPA 216 + EP + L PE SSP + P P P+ ++ +P P+P Sbjct: 1247 AVPTLEEPTSSAAAV-LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305 Query: 217 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 266 + S P + + A+ PP + +P P A + + EE Sbjct: 1306 AAIPAASVPTPEVPAIPAAAVPP-MEEVSPIGVPFLGVSAHTDSVPISEE 1354 Score = 52.4 bits (124), Expect = 3e-06 Identities = 95/375 (25%), Positives = 124/375 (33%), Gaps = 63/375 (16%) Query: 30 VAVIVRPDDRSQGAIIADR--PGLPGPEHSPSESQPSSPSPT-------PSPSPVLEPGS 80 + V+ RP + + D LP PE S + +P T P P + S Sbjct: 828 IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887 Query: 81 EPNL-------AVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSP--------EPTPL 124 +L A +S P T+ + +SV E T P +P E Sbjct: 888 IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947 Query: 125 AEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPEL 184 L+ VP +E +P TP TV E PE +SP Sbjct: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPAT--TVHAPEEPDTAAVRVSTPEEPASPAA 1005 Query: 185 APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSA 244 A P P E P A PEE P+ PA + P EP A V + PT P+A Sbjct: 1006 AVP--TPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEEPTSPAAAV-PTPEEPTSPAA 1057 Query: 245 TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLE 304 T TSPA + EE A E + PE PA E Sbjct: 1058 AVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115 Query: 305 AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANP--AVPEVENQP-PAGSNPGPE 361 A+ AV P+ + A+P AVP E PA + P PE Sbjct: 1116 EPASPAAAVPTPE---------------------EPASPAAAVPTPEEPAFPAPAVPTPE 1154 Query: 362 SEGSG--VPPRPEEA 374 S P PEE+ Sbjct: 1155 ESASAAVAVPTPEES 1169 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 70.9 bits (172), Expect = 8e-12 Identities = 109/487 (22%), Positives = 187/487 (38%), Gaps = 34/487 (6%) Query: 213 SPPAVDL-SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271 SPPA + SP E + KE S A P A +P+ ++ + +EE + Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562 Query: 272 AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAV 331 ++ E E K E+ PE PA E A + A S K + +KE K A Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAK-----EEAKSPAEAKSPEKAKSPVKEEAKSPA- 616 Query: 332 GDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENI 391 + KE + EV++ A S E++ PE+ + K AE Sbjct: 617 -EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675 Query: 392 QPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKT 451 P + K K++ P E+ K +E + + +++ P + + + KT Sbjct: 676 SPEKAKSPVKAEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732 Query: 452 PLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQG 511 P + P + + + +P A TL + P P E R PA P +++ Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAK----TLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788 Query: 512 PRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 568 ++E P K A + ED K + E K K ++++ +E K ++ ++ Sbjct: 789 VKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE----VKVKEPPKKA 842 Query: 569 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 628 TP+ ++ K + +E K ++ E A+ +P S A Sbjct: 843 EEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900 Query: 629 LKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD-------EVFEKKQKEMDEAATAEE 680 KVPT EK V ++ + + E K + DD + EKK+ ++ T EE Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960 Query: 681 RGRLKEE 687 + + EE Sbjct: 961 KAKKPEE 967 Score = 67.4 bits (163), Expect = 9e-11 Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 39/364 (10%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 PE + S + + SP + SPV P A + + + + +P+ E Sbjct: 649 PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP----EKAKSPVKEEAKS 704 Query: 114 PYRL-------SPEPTPLAEPILEVEVTLSKPV-PESEFSSSPLQAPTPLASHTVEIHEP 165 P + + P P+ E T K P E + SP +A +P + T+++ P Sbjct: 705 PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764 Query: 166 NGMVPS-EDLEPEVESSPELAPPPA-----CPSESPVPIAPTAQ-PEELL---NGAPSPP 215 P+ E+ + PE A P P ++ P+ A+ PE+ + SP Sbjct: 765 EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824 Query: 216 AVDLSP----VSEPEEQAKEVTASMAPPTIPSATP----ATAPSATSPAQEEEMEEEEEE 267 + P V EP ++A+E A P T A A P EE+ E E+ Sbjct: 825 KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884 Query: 268 EEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVP---KRRRKIKE 324 + EA + E+E + P + P + ++ + T+VA P K + K Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944 Query: 325 LNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPE----EADETWDS 380 KKEA + D KE PE + + A + ++ S P +P+ E + D Sbjct: 945 AEKKEAAPEKKDT-KEEKAKKPEEKPKTEAKAKEDDKTL-SKEPSKPKAEKAEKSSSTDQ 1002 Query: 381 KEDK 384 K+ K Sbjct: 1003 KDSK 1006 Score = 61.6 bits (148), Expect = 5e-09 Identities = 99/425 (23%), Positives = 160/425 (37%), Gaps = 45/425 (10%) Query: 17 GGLEPQANG-----ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 71 GG E +A G ++P P+ ++ + + P SP + + SP+ S Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSPAEVKS 546 Query: 72 P----SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE--STPISRETGEPYRL-SPE--PT 122 P SP E P A + + ++ E +P E P SPE + Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606 Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P+ E E + P E + SP + +P + + E ++ E E SP Sbjct: 607 PVKE---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663 Query: 183 ELAPPPA-----CPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP-EEQAKEVTASM 236 E A P P ++ P+ A+ E A P +E+AK + Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723 Query: 237 APPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG----EAGEAESEKGGEELLPPES 292 +P + TP A SP +EE E+ + +A ++ EA++ E P + Sbjct: 724 SPVKEEAKTP---EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780 Query: 293 TPIPANLSQNLEAAAATQVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPEVEN 350 P A S E + + A S K K KE+ KKE V +P E + Sbjct: 781 FPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV---------KSPVKEEEKP 830 Query: 351 QPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPG-EQKYEYKSDQWKPLN 409 Q P ++E P P + +E DSK+++ E +P E+K E ++ K Sbjct: 831 QEVKVKEPPKKAEEEKAPATP-KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889 Query: 410 LEEKK 414 +E KK Sbjct: 890 VEAKK 894 Score = 54.3 bits (129), Expect = 8e-07 Identities = 85/367 (23%), Positives = 134/367 (36%), Gaps = 28/367 (7%) Query: 61 SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120 S P PS S ++ SE + V+ ++ EE+ T E + + E Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480 Query: 121 PTPLAEPILEVEVTL-----SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 175 E E E +K P E +S +A +P+ E E Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540 Query: 176 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-SPPAVDLSPVSEPEE---QAKE 231 P SPE A PA P A + + EE + A P SP E + +AK Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600 Query: 232 VTASMAPPTIPSATPATAPS-----ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 286 + +P + +PA A S A SPA+ + E+ + + EA +A+S + EE Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEE 659 Query: 287 LLPPESTPIPANLSQNLEAAAATQV---AVSVPKRRRKIKELNK-----KEAVGDLLDAF 338 PE P A + V A S K + +KE K K V + + Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 719 Query: 339 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKY 398 ++A V E P +P E S PE+A +K + + E P +++ Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKS-----PEKAKSPEKAKTLDVKSPEAKTPAKEEA 774 Query: 399 EYKSDQW 405 +D++ Sbjct: 775 RSPADKF 781 Score = 53.5 bits (127), Expect = 1e-06 Identities = 132/625 (21%), Positives = 214/625 (34%), Gaps = 90/625 (14%) Query: 72 PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 131 P P P P + +S T I++ EE + ++ + + E T + EV Sbjct: 417 PIPFSLPEGLPKIPSVS------THIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470 Query: 132 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPAC 190 K E E E P P+E+ PE E+ + Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP----PAEEAASPEKEAKSPVKEEAKS 526 Query: 191 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATA 249 P+E+ P A+ P E+ + + S PE ++ E + +P + S A + Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586 Query: 250 PS---ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAA 306 P+ A SPA+ + E+ + + EA EA+S E P E S E A Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646 Query: 307 AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 366 + + A S K K E K +A PE P PE S Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV---------KAEAKSPEKAKSPVKAEAKSPEKAKS- 696 Query: 367 VPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQF 426 P EEA +K A++ P + K K + P EK + Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKS--PEKAKSPVKEEAKTP----EKAK----------- 737 Query: 427 IFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRG 486 S K E K+P + P + + TL + Sbjct: 738 ---SPVKEEA-------------KSPEKAKSPEKAK------------------TLDVKS 763 Query: 487 PPRGGPGGELPRGPAGLGPRRSQQGPRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSK 543 P P E R PA P +++ ++E P K A + ED K + E K K Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVK 821 Query: 544 RTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVID 603 ++++ +E K ++ ++ TP+ ++ K + +E K ++ Sbjct: 822 SPVKEEEKPQE----VKVKEPPKKAEEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVE 875 Query: 604 LIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD 662 E A+ +P S A KVPT EK V ++ + + E K + DD Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935 Query: 663 EVFEKKQKEMDEAATAEERGRLKEE 687 ++ K ++ A E+ KEE Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEE 960 Score = 32.3 bits (72), Expect = 3.3 Identities = 39/208 (18%), Positives = 68/208 (32%), Gaps = 28/208 (13%) Query: 21 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS 80 P E PQ + P +++ P + S E P +P P EP Sbjct: 823 PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP-- 880 Query: 81 EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 140 ++ E +E E + P P A +EV+ +KP Sbjct: 881 ---------------AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED-AKPKE 924 Query: 141 ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 200 ++E + + EP+ ++ PE + + E P E P A Sbjct: 925 KTEVAKK--------EPDDAKAKEPSKPAEKKEAAPEKKDTKE--EKAKKPEEKPKTEAK 974 Query: 201 TAQPEELLNGAPSPPAVDLSPVSEPEEQ 228 + ++ L+ PS P + + S +Q Sbjct: 975 AKEDDKTLSKEPSKPKAEKAEKSSSTDQ 1002 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 68.9 bits (167), Expect = 3e-11 Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P P S PS P PS P + N LS+PG ++ + + Sbjct: 678 PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737 Query: 114 PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 167 P L+P TP P + + T VP F +S ++ S + P G Sbjct: 738 PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794 Query: 168 MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 221 + P P + P +AP P+ SP P+ +PEEL L P PP P Sbjct: 795 LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852 Query: 222 VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 279 V+ P Q + PP + +++ +EEE EEEEEEEE E E E Sbjct: 853 VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912 Query: 280 SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 339 E+ EE E + E + + +EL + E + + A Sbjct: 913 EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970 Query: 340 EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 393 E P PPA P PES P P PE E +E +E A + P Sbjct: 971 EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028 Score = 68.9 bits (167), Expect = 3e-11 Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 28/312 (8%) Query: 10 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69 P PP +G P A P + V + + + P PGP P P P P Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----ELPAAPGPLPPPPPPPPPVPGPV 853 Query: 70 PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EESTPISRETGEPYRLSPEPTPLAE 126 P P L P P + +T I ++ EE E E E E Sbjct: 854 TLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913 Query: 127 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--HEPNGMVPSEDLE-----PEVE 179 E E + E EF + L E E + EDLE EVE Sbjct: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973 Query: 180 SSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAVDLSPVSEP---EEQAKEVTAS 235 PPP P P P +P QPE P P L V EP EE+ + + Sbjct: 974 EGAP--PPPTLPPALPPPESPPKVQPE------PEPEPGLLLEVEEPGTEEERGADTAPT 1025 Query: 236 MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 295 +AP +PS SPA +E EEE E E+E G +++ PP TP Sbjct: 1026 LAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084 Query: 296 PANLSQNLEAAA 307 + EA A Sbjct: 1085 EEEMETETEAEA 1096 Score = 45.8 bits (107), Expect = 3e-04 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%) Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P P+ + T P P P +AP+P + H P M P V S P Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678 Query: 183 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 238 P P+ PS PVP A P + G P V + P P + ++ P Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738 Query: 239 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 291 PS TP P T + ++EE + + E++S+ E LPP Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798 Query: 292 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 351 P P+ + A A + + +EL A L P VP Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855 Query: 352 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 401 PP P + G G PP EE +DE + +E++ E + E+ +E + Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914 Query: 402 --SDQWKPLNLEEKKRYDREF 420 +++ EE++ ++ EF Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935 Score = 31.6 bits (70), Expect = 5.6 Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%) Query: 652 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 690 +++FE++++D+E + E++++E E EE G L+EE EE Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 67.4 bits (163), Expect = 9e-11 Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 44/250 (17%) Query: 3 GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62 GA A PPQ G + E+P+ P P P P +P Sbjct: 4 GAAAAQGTAPPQDG-----EQPAESPEPPPPWPPP-----------PPPPAPPPAPPLLS 47 Query: 63 PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122 +SP P P P P L PG P S T + + E +T + E P P Sbjct: 48 EASPEPIPEPCPELAPGPCPEATSESA---TELYTEPTPEPATEPASEPAPEPATEPAPE 104 Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P EP E P PE S+P P P E P+ +L PEV +P Sbjct: 105 PATEPAPE-------PAPEPATESAPEPTPEPALESVPE--------PAPELTPEV--AP 147 Query: 183 ELAPPPACPSESPVPIAPTAQPEELLNGAPSP-PAVDLSPVSEPEEQAKEVTASMAPPTI 241 ELAP P E +AP PE PSP P + PV E K +P Sbjct: 148 ELAPEPT--PEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK-----TSPSPS 200 Query: 242 PSATPATAPS 251 PS +P T S Sbjct: 201 PSPSPRTPMS 210 Score = 44.7 bits (104), Expect = 6e-04 Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 19/159 (11%) Query: 110 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 169 + GE SPEP P P P SE S P+ P P + G Sbjct: 15 QDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP--------GPC 66 Query: 170 PSEDLEPEVESSPELAPPPAC-PSESPVPIAPTAQ-PEELLNGAPSP---PAVDLSPVSE 224 P E E E P PA P+ P P T PE AP P PA + +P Sbjct: 67 PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPT 126 Query: 225 PEEQAKEVTASMAPPTIPSATPATAPS-ATSPAQEEEME 262 PE + V P P TP AP A P E E Sbjct: 127 PEPALESV-----PEPAPELTPEVAPELAPEPTPEPVTE 160 Score = 43.9 bits (102), Expect = 0.001 Identities = 44/141 (31%), Positives = 52/141 (36%), Gaps = 20/141 (14%) Query: 167 GMVPSEDLEPEVESS----------PELAPPPACPSESPVPIAPTAQPEELLNGAPSPPA 216 G P +D E ES P APPPA P S P +P L P P A Sbjct: 10 GTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69 Query: 217 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 276 S E E P T P++ PA P AT PA E E E A E+ Sbjct: 70 TSESATELYTEPTPE------PATEPASEPAPEP-ATEPAPEPATEPAPEPAPEPATESA 122 Query: 277 EAESEKGGEELLP---PESTP 294 + + E +P PE TP Sbjct: 123 PEPTPEPALESVPEPAPELTP 143 >gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] Length = 1120 Score = 67.4 bits (163), Expect = 9e-11 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%) Query: 3 GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 58 G TA G L P+ G P+ + SQ +I A G + P Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 633 Query: 59 SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 114 + QPS P+P L G+E P S+PG + +P S G P Sbjct: 634 AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 692 Query: 115 -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 166 Y P TP P + +LS+P P + + P + L S+ P Sbjct: 693 PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 752 Query: 167 GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 215 V +SP + P PA + A P P + L+ +P PP Sbjct: 753 RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 805 Query: 216 AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271 +D SP P+E A + + A P+ P PA A A+ +EE E G Sbjct: 806 PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 863 Query: 272 AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 323 +GE G +E+G + PP TP+P L NL + KRR K + Sbjct: 864 SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 915 Query: 324 ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 368 E +E + L AF A+ PA P PPA S P PE GVP Sbjct: 916 E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 968 Score = 42.4 bits (98), Expect = 0.003 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%) Query: 4 ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 54 AR P PP +G EP E+P + A R S+ A ++ PG P P Sbjct: 781 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 840 Query: 55 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114 S+++ P P +P P + L + TI+ + + P RET P Sbjct: 841 AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 895 Query: 115 ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159 + L+ T PL +L V + P P ++PL +PTP S Sbjct: 896 PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 948 Query: 160 VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219 P S P+ P P P+AP+ + + P P ++ Sbjct: 949 ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 991 Query: 220 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256 S S + + A A +P A TAP S A Sbjct: 992 SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1026 Score = 32.7 bits (73), Expect = 2.5 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 54 +G TP PP L +T + R + Q A++A P P P Sbjct: 885 AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 941 Query: 55 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114 +P ES P+S P P PS + G LA + ES+ SR GE Sbjct: 942 SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1000 Query: 115 YRLSPEPTPLAEPILEVEVTLSKPVPES 142 EP +L+V + P P S Sbjct: 1001 ----TEPPAAPAALLKVPGAGTAPKPVS 1024 >gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] Length = 1202 Score = 67.4 bits (163), Expect = 9e-11 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%) Query: 3 GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 58 G TA G L P+ G P+ + SQ +I A G + P Sbjct: 656 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 715 Query: 59 SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 114 + QPS P+P L G+E P S+PG + +P S G P Sbjct: 716 AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 774 Query: 115 -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 166 Y P TP P + +LS+P P + + P + L S+ P Sbjct: 775 PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 834 Query: 167 GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 215 V +SP + P PA + A P P + L+ +P PP Sbjct: 835 RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 887 Query: 216 AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271 +D SP P+E A + + A P+ P PA A A+ +EE E G Sbjct: 888 PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 945 Query: 272 AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 323 +GE G +E+G + PP TP+P L NL + KRR K + Sbjct: 946 SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 997 Query: 324 ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 368 E +E + L AF A+ PA P PPA S P PE GVP Sbjct: 998 E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 1050 Score = 42.4 bits (98), Expect = 0.003 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%) Query: 4 ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 54 AR P PP +G EP E+P + A R S+ A ++ PG P P Sbjct: 863 ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 922 Query: 55 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114 S+++ P P +P P + L + TI+ + + P RET P Sbjct: 923 AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 977 Query: 115 ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159 + L+ T PL +L V + P P ++PL +PTP S Sbjct: 978 PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 1030 Query: 160 VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219 P S P+ P P P+AP+ + + P P ++ Sbjct: 1031 ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 1073 Query: 220 SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256 S S + + A A +P A TAP S A Sbjct: 1074 SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1108 Score = 32.7 bits (73), Expect = 2.5 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%) Query: 2 SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 54 +G TP PP L +T + R + Q A++A P P P Sbjct: 967 AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 1023 Query: 55 EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114 +P ES P+S P P PS + G LA + ES+ SR GE Sbjct: 1024 SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1082 Query: 115 YRLSPEPTPLAEPILEVEVTLSKPVPES 142 EP +L+V + P P S Sbjct: 1083 ----TEPPAAPAALLKVPGAGTAPKPVS 1106 >gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 67.0 bits (162), Expect = 1e-10 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P ++P+ + S P+ TPS +P L P S+P L S P T ++ +TP + Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63 Query: 114 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173 P L+P TP P +T P P SS+P TP + T+ + PS Sbjct: 64 P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117 Query: 174 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 227 ++P L P P PS +P + P+++P +L + +P L+P S P Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171 Query: 228 QAKEVTASMAPPTIPSATPATAPSAT 253 +T S P PS+TP PS+T Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197 Score = 60.8 bits (146), Expect = 9e-09 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%) Query: 11 TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 70 TP T TP + P Q + P P+ + ++P+ TP Sbjct: 55 TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114 Query: 71 SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 130 S +P L P + P L S P T ++ S PI + +P TP + PIL Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169 Query: 131 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 187 T + P S + +P PT S T + PS S+P L P P Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222 Query: 188 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 247 PS +P + P+++P +L + +P S + +T S P PS TP Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279 Query: 248 TAPSAT 253 PS+T Sbjct: 280 LTPSST 285 Score = 37.0 bits (84), Expect = 0.13 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P P ++ S+P+ TPS +P L P + P L P +T T + TP S T Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287 Query: 114 PYRLSPEPTPLAEP 127 L+P TP P Sbjct: 288 ---LTPSSTPTLTP 298 Score = 32.7 bits (73), Expect = 2.5 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 97 P ++P+ + ++P+ TPS +P L P S P L S P T +++ Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301 Score = 31.6 bits (70), Expect = 5.6 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%) Query: 140 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 199 P + + +P PT S T + + + + P + S +PP PS +P + Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59 Query: 200 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255 P+ P + P+ L+P S P + + + PT+ ++P T + +P Sbjct: 60 PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110 >gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 67.0 bits (162), Expect = 1e-10 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P ++P+ + S P+ TPS +P L P S+P L S P T ++ +TP + Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63 Query: 114 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173 P L+P TP P +T P P SS+P TP + T+ + PS Sbjct: 64 P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117 Query: 174 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 227 ++P L P P PS +P + P+++P +L + +P L+P S P Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171 Query: 228 QAKEVTASMAPPTIPSATPATAPSAT 253 +T S P PS+TP PS+T Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197 Score = 60.8 bits (146), Expect = 9e-09 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%) Query: 11 TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 70 TP T TP + P Q + P P+ + ++P+ TP Sbjct: 55 TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114 Query: 71 SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 130 S +P L P + P L S P T ++ S PI + +P TP + PIL Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169 Query: 131 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 187 T + P S + +P PT S T + PS S+P L P P Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222 Query: 188 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 247 PS +P + P+++P +L + +P S + +T S P PS TP Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279 Query: 248 TAPSAT 253 PS+T Sbjct: 280 LTPSST 285 Score = 37.0 bits (84), Expect = 0.13 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P P ++ S+P+ TPS +P L P + P L P +T T + TP S T Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287 Query: 114 PYRLSPEPTPLAEP 127 L+P TP P Sbjct: 288 ---LTPSSTPTLTP 298 Score = 32.7 bits (73), Expect = 2.5 Identities = 15/44 (34%), Positives = 26/44 (59%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 97 P ++P+ + ++P+ TPS +P L P S P L S P T +++ Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301 Score = 31.6 bits (70), Expect = 5.6 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%) Query: 140 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 199 P + + +P PT S T + + + + P + S +PP PS +P + Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59 Query: 200 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255 P+ P + P+ L+P S P + + + PT+ ++P T + +P Sbjct: 60 PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110 >gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] Length = 280 Score = 66.6 bits (161), Expect = 2e-10 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 20/230 (8%) Query: 36 PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 95 P + + P P ++P+ + S+P+ TP +P L P + P L S P T + Sbjct: 46 PREMGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPS 105 Query: 96 TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--- 152 + STP + P L+P TP P +T S P SS+P P Sbjct: 106 STPTLTPSSTPTLTPSSTP-TLTPSSTPTLTPSSTPTLTRSS-TPTLTPSSTPTLTPSST 163 Query: 153 ---TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---PPACPSESPVPIAPTAQPEE 206 TP ++ T+ + PS S+P L P P PS +P + P+ P Sbjct: 164 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPT-LTPSNTPTL 222 Query: 207 LLNGAPSPPAVDLSPVSEP---EEQAKEVTASMAPPTIPSATPATAPSAT 253 + + P+ L+P S P +T S P PS+TP PS+T Sbjct: 223 IPSSTPT-----LTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSST 267 Score = 36.2 bits (82), Expect = 0.23 Identities = 19/53 (35%), Positives = 27/53 (50%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP 106 P ++P+ S+P+ TPS +P L P S P L S P T ++ STP Sbjct: 216 PSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSSTP 268 Score = 35.0 bits (79), Expect = 0.51 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 9/74 (12%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113 P +P+ + ++P+ PS +P L P S P L S P T ++ STP Sbjct: 208 PSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTP------- 260 Query: 114 PYRLSPEPTPLAEP 127 L+P TP P Sbjct: 261 --TLTPSSTPTLTP 272 Score = 31.6 bits (70), Expect = 5.6 Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 54 PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSI 89 P P+ ++ S+P+ TPS +P L P S P L S+ Sbjct: 240 PSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSL 275 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 65.1 bits (157), Expect = 5e-10 Identities = 71/312 (22%), Positives = 106/312 (33%), Gaps = 52/312 (16%) Query: 10 PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69 P PP G P P++A+ VRP + +I A P P +P+ + P P Sbjct: 853 PAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPV 912 Query: 70 PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPIL 129 P P P+ P + P A IP + + P R+ P+P P + Sbjct: 913 PPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP---------RIGPQPQPHPQ--- 960 Query: 130 EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP- 188 P P F P Q P PL + + G++P + P L PP Sbjct: 961 --------PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPP 1012 Query: 189 -------ACPSESPVPI----------APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 231 P++ P+P P P L P+P + P + P Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGP 1072 Query: 232 VTASMAPPT---IPSATPATAPSATSPAQEEEMEEEEEEEEGEA----------GEAGEA 278 +A + P+ +PS P+ P P + E G A + G Sbjct: 1073 SSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGT 1131 Query: 279 ESEKGGEELLPP 290 +S GG+ LL P Sbjct: 1132 QSPGGGQPLLQP 1143 Score = 40.4 bits (93), Expect = 0.012 Identities = 68/282 (24%), Positives = 94/282 (33%), Gaps = 50/282 (17%) Query: 21 PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS-PSPTPSPSPVLEPG 79 P + G P P G +P PGP P P+ P+P +P L P Sbjct: 777 PSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPR 836 Query: 80 SEPNLAVLSI-------------------PGDTMTTIQMSVEEST--------PISRETG 112 S P V+S P + + M+V +T PI T Sbjct: 837 SSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTA 896 Query: 113 EPYRLSPEPTPLAEPI-----LEVEVT----LSKPVPESEFSSSPLQA--PTPLASHTVE 161 +P P P P+ L T +P+P SS + A P P + Sbjct: 897 PRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQ 956 Query: 162 IH-EPN---GMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELLNGAPSP 214 H +P+ P +P P L PP A P +SP P AP QP L G P P Sbjct: 957 PHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAP--QPGVL--GQPPP 1012 Query: 215 PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256 P ++ + ++ P+ P P A PA Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPA 1054 Score = 32.3 bits (72), Expect = 3.3 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%) Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182 P +P+ ++ +P+ L P++S I + + + P LE V S P Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521 Query: 183 ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 242 A PP P P + PE + SPP P+S P +A + P P Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568 Query: 243 SATPATA 249 S+ P ++ Sbjct: 1569 SSGPPSS 1575 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.130 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,805,254 Number of Sequences: 37866 Number of extensions: 3811416 Number of successful extensions: 49199 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 468 Number of HSP's successfully gapped in prelim test: 1910 Number of HSP's that attempted gapping in prelim test: 26012 Number of HSP's gapped (non-prelim): 15885 length of query: 1403 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1288 effective length of database: 13,892,928 effective search space: 17894091264 effective search space used: 17894091264 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.