Guide to the Human Genome
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Search of human proteins with 38201619

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
isoform 4 [Homo sapiens]
         (1403 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|38201627 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|38201625 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|38201619 eukaryotic translation initiation factor 4 gamma, 1 ...  2784   0.0  
gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 ...  1171   0.0  
gi|110630018 eukaryotic translation initiation factor 4 gamma, 2...   196   1e-49
gi|4503539 eukaryotic translation initiation factor 4 gamma, 2 i...   196   1e-49
gi|33386693 poly(A) binding protein interacting protein 1 isofor...    81   8e-15
gi|17511255 poly(A) binding protein interacting protein 1 isofor...    81   8e-15
gi|169212085 PREDICTED: similar to poly(A) binding protein inter...    78   7e-14
gi|239752553 PREDICTED: similar to poly(A) binding protein inter...    78   7e-14
gi|89041275 PREDICTED: similar to poly(A) binding protein intera...    78   7e-14
gi|34452730 poly(A) binding protein interacting protein 1 isofor...    77   9e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   3e-13
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    74   1e-12
gi|116284392 mucin 2 precursor [Homo sapiens]                          72   4e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    72   4e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    72   4e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    72   5e-12
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             71   8e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     71   8e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    69   3e-11
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 67   9e-11
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       67   9e-11
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       67   9e-11
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi...    67   1e-10
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi...    67   1e-10
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            67   2e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    65   5e-10

>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 197  MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256

Query: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 257  SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316

Query: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 317  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376

Query: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 377  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436

Query: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 437  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496

Query: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 497  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556

Query: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 557  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616

Query: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 617  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676

Query: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 677  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736

Query: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 737  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796

Query: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 797  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856

Query: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 857  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916

Query: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 917  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976

Query: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 977  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036

Query: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096

Query: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156

Query: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216

Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276

Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336

Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396

Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456

Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516

Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576

Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1577 VALKSVTAFFKWLREAEEESDHN 1599



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)

Query: 63  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118
           P S  P P+PSP L   + P       PG T   +     + + +TP   R+   P R  
Sbjct: 5   PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57

Query: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173
           P P+  A  +         P        S+    P Q   P +     I    G   S  
Sbjct: 58  P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113

Query: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221
           + P  +   +   P   P  SP           P    ++   G AP+P  ++  P    
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173

Query: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265
                   + +P +  K++T  +       + PT P       P A     Q   +   +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233

Query: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322
           +  +G   A   G    E    E  P   +P P+  S  LE  +   +AV S+P      
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292

Query: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376
            +++ +E+       G+      E  P    +       S P PESE S     P +A  
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349

Query: 377 TWDSKEDKIHNAENIQPGE 395
              S   +IH    + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368


>gi|38201627 eukaryotic translation initiation factor 4 gamma, 1
            isoform 2 [Homo sapiens]
          Length = 1512

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 110  MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 169

Query: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 170  SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 229

Query: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 230  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 289

Query: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 290  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 349

Query: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 350  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 409

Query: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 410  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 469

Query: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 470  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 529

Query: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 530  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 589

Query: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 590  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 649

Query: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 650  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 709

Query: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 710  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 769

Query: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 770  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 829

Query: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 830  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 889

Query: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 890  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 949

Query: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 950  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1009

Query: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 1010 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1069

Query: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 1070 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1129

Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1130 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1189

Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1190 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1249

Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1250 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1309

Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1310 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1369

Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1370 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1429

Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1430 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1489

Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1490 VALKSVTAFFKWLREAEEESDHN 1512


>gi|38201625 eukaryotic translation initiation factor 4 gamma, 1
            isoform 3 [Homo sapiens]
          Length = 1435

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 33   MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 92

Query: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 93   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 152

Query: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 153  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 212

Query: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 213  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 272

Query: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 273  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 332

Query: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 333  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 392

Query: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 393  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 452

Query: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 453  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 512

Query: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 513  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 572

Query: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 573  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 632

Query: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 633  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 692

Query: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 693  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 752

Query: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 753  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 812

Query: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 813  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 872

Query: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 873  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 932

Query: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 933  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 992

Query: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 993  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1052

Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1053 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1112

Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1113 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1172

Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1173 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1232

Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1233 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1292

Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1293 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1352

Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1353 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1412

Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1413 VALKSVTAFFKWLREAEEESDHN 1435


>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
            isoform 1 [Homo sapiens]
          Length = 1599

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 197  MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 256

Query: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 257  SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 316

Query: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 317  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 376

Query: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 377  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 436

Query: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 437  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 496

Query: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 497  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 556

Query: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 557  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 616

Query: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 617  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 676

Query: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 677  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 736

Query: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 737  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 796

Query: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 797  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 856

Query: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 857  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 916

Query: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 917  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 976

Query: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 977  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 1036

Query: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 1037 GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 1096

Query: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 1097 SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 1156

Query: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 1157 RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1216

Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1217 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1276

Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1277 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1336

Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1337 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1396

Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1397 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1456

Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1457 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1516

Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1517 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1576

Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1577 VALKSVTAFFKWLREAEEESDHN 1599



 Score = 33.5 bits (75), Expect = 1.5
 Identities = 81/379 (21%), Positives = 126/379 (33%), Gaps = 61/379 (16%)

Query: 63  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI---QMSVEESTPIS-RETGEPYRLS 118
           P S  P P+PSP L   + P       PG T   +     + + +TP   R+   P R  
Sbjct: 5   PQSTGPPPAPSPGLPQPAFP-------PGQTAPVVFSTPQATQMNTPSQPRQHFYPSRAQ 57

Query: 119 PEPTPLAEPILEVEVTLSKPVPE-----SEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173
           P P+  A  +         P        S+    P Q   P +     I    G   S  
Sbjct: 58  P-PSSAASRVQSAAPARPGPAAHVYPAGSQVMMIPSQISYPASQGAYYI---PGQGRSTY 113

Query: 174 LEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG-APSPPAVDLSP---- 221
           + P  +   +   P   P  SP           P    ++   G AP+P  ++  P    
Sbjct: 114 VVPTQQYPVQPGAPGFYPGASPTEFGTYAGAYYPAQGVQQFPTGVAPAPVLMNQPPQIAP 173

Query: 222 --------VSEPEEQAKEVTASM-------APPTIPSATPATAPSATSPA-QEEEMEEEE 265
                   + +P +  K++T  +       + PT P       P A     Q   +   +
Sbjct: 174 KRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD 233

Query: 266 EEEEGE--AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAV-SVPKRRRKI 322
           +  +G   A   G    E    E  P   +P P+  S  LE  +   +AV S+P      
Sbjct: 234 DRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSP-SPVLEPGSEPNLAVLSIPGDTMTT 292

Query: 323 KELNKKEA------VGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADE 376
            +++ +E+       G+      E  P    +       S P PESE S     P +A  
Sbjct: 293 IQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS---SPLQAPT 349

Query: 377 TWDSKEDKIHNAENIQPGE 395
              S   +IH    + P E
Sbjct: 350 PLASHTVEIHEPNGMVPSE 368


>gi|38201619 eukaryotic translation initiation factor 4 gamma, 1
            isoform 4 [Homo sapiens]
          Length = 1403

 Score = 2784 bits (7218), Expect = 0.0
 Identities = 1403/1403 (100%), Positives = 1403/1403 (100%)

Query: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE
Sbjct: 1    MSGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60

Query: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
            SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE
Sbjct: 61   SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120

Query: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES
Sbjct: 121  PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180

Query: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240
            SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT
Sbjct: 181  SPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPT 240

Query: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300
            IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS
Sbjct: 241  IPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLS 300

Query: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360
            QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP
Sbjct: 301  QNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGP 360

Query: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420
            ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF
Sbjct: 361  ESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREF 420

Query: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480
            LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT
Sbjct: 421  LLGFQFIFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRT 480

Query: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540
            TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP
Sbjct: 481  TLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKP 540

Query: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600
            SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG
Sbjct: 541  SSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKG 600

Query: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660
            VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD
Sbjct: 601  VIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKD 660

Query: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720
            DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM
Sbjct: 661  DDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIM 720

Query: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780
            HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR
Sbjct: 721  HDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIR 780

Query: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840
            FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP
Sbjct: 781  FMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPP 840

Query: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900
            GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG
Sbjct: 841  GPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGGRLSWGKG 900

Query: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960
            SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD
Sbjct: 901  SSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTESTDNRRVVQRSSLSRERGEKAGD 960

Query: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020
            RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR
Sbjct: 961  RGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQPEGLRKAASLTEDRDR 1020

Query: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080
            GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF
Sbjct: 1021 GRDAVKREAALPPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPSLLF 1080

Query: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140
            IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV
Sbjct: 1081 IFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHV 1140

Query: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200
            WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW
Sbjct: 1141 WLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLW 1200

Query: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260
            REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS
Sbjct: 1201 REAGLSWKEFLPEGQDIGAFVAEQKVEYTLGEESEAPGQRALPSEELNRQLEKLLKEGSS 1260

Query: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320
            NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC
Sbjct: 1261 NQRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAIIFETPLRVDVAVLKARAKLLQKYLC 1320

Query: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380
            DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG
Sbjct: 1321 DEQKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDPAEQQGKG 1380

Query: 1381 VALKSVTAFFKWLREAEEESDHN 1403
            VALKSVTAFFKWLREAEEESDHN
Sbjct: 1381 VALKSVTAFFKWLREAEEESDHN 1403


>gi|10092601 eukaryotic translation initiation factor 4 gamma, 3 [Homo
            sapiens]
          Length = 1585

 Score = 1171 bits (3029), Expect = 0.0
 Identities = 728/1489 (48%), Positives = 912/1489 (61%), Gaps = 166/1489 (11%)

Query: 5    RTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPS 64
            R  STPTPPQ    L  Q    +P V   V      + A +A    +        E +P 
Sbjct: 173  RPTSTPTPPQQ---LPSQVPEHSPVVYGTV------ESAHLAASTPVTAASDQKQEEKPK 223

Query: 65   SPSPTPSPSPVL----------------EPGSEPNLAVLSIPGD--TMTTIQMSVEESTP 106
                  SPSPVL                E  +  ++A L +P    T++++  S   +  
Sbjct: 224  PDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPT 283

Query: 107  ISRETGEPYRL----------SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT--- 153
             S  + +P             SP    +  P L      S P+P +E      + P    
Sbjct: 284  SSALSSQPIFTTAIDDRCELSSPREDTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVA 343

Query: 154  ----PLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLN 209
                PL S T  I+E NG+  SE L    ES  E+      P    + I      E  L 
Sbjct: 344  PNDIPLVSSTNLINEINGV--SEKLSA-TESIVEIVKQEVLPLTLELEILENPPEEMKLE 400

Query: 210  GAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQ----EEEMEEEE 265
              P+P    ++P + P       T   +PP  P   PA A + +SP+     +  +EE+E
Sbjct: 401  CIPAP----ITPSTVPSFPPTPPTPPASPPHTPVIVPAAATTVSSPSAAITVQRVLEEDE 456

Query: 266  E------EEEGEAGEAGEAESEKGGEELLPPES-----TPIPANLSQNLEAAAATQVAVS 314
                   E+  E     E E++   EE+L  ++     +P+PA            Q+A++
Sbjct: 457  SIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPA------------QIAIT 504

Query: 315  VPKRRRKIKELNK--KEAVGDLLDAFKEANPAVPEVENQPPAGSNPG--PESEGSGVPPR 370
            VPK  +K K+  +  +E +   L+   E   ++ +V        + G  PE + S +  +
Sbjct: 505  VPKTWKKPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMSQGFHPERDPSDLK-K 563

Query: 371  PEEADETWDSKEDKIHNAENIQPGEQ---------------KYEYKSDQWKPLNLEEKKR 415
             +  +E  +  E   + AE++  GE                 + +K + WKP + E KK+
Sbjct: 564  VKAVEENGEEAEPVRNGAESVSEGEGIDANSGSTDSSGDGVTFPFKPESWKPTDTEGKKQ 623

Query: 416  YDREFLLGFQFIFASMQKPEGLPHISDVVLDKAN--KTPLRPLDPTRLQGINCGPDFTPS 473
            YDREFLL FQF+ A +QKPEGLP ISDVVLDK N  K P+R LDP  L     GPDFTP+
Sbjct: 624  YDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPR---GPDFTPA 680

Query: 474  FANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQGPRKEPRKIIATVLMTEDIKLNK 533
            FA+ GR T   RG P              +G RRSQ G R+EPRKII TV + ED+ L K
Sbjct: 681  FADFGRQTPGGRGVPL-----------LNVGSRRSQPGQRREPRKII-TVSVKEDVHLKK 728

Query: 534  AEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAID 593
            AE AWKPS KR     D   +D +  KTQ+LFR+VRSILNKLTPQMF QLMKQV+ L +D
Sbjct: 729  AENAWKPSQKR-----DSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLTVD 783

Query: 594  TEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQK 653
            TEERLKGVIDL+FEKAI EP+FSVAYANMCRCL+ LKVP  +KP  TVNFRKLLLNRCQK
Sbjct: 784  TEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMADKPGNTVNFRKLLLNRCQK 843

Query: 654  EFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELFKLK 713
            EFEKDK DD+VFEKKQKE++ A+  EER RL +ELEEA+D ARRRS+GNIKFIGELFKLK
Sbjct: 844  EFEKDKADDDVFEKKQKELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLK 903

Query: 714  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEK 773
            MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKI+KE+
Sbjct: 904  MLTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIVKER 963

Query: 774  KTSSRIRFMLQDVLDLRGSNWVPRRGDQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSD 833
            KTSSRIRFMLQDV+DLR  NWV RR DQGPKTI+QIHKEA++EE  E  KVQQLM K  +
Sbjct: 964  KTSSRIRFMLQDVIDLRLCNWVSRRADQGPKTIEQIHKEAKIEEQEEQRKVQQLMTK--E 1021

Query: 834  KRRGGPPGPPISRGLPLVDDGGWNTVPISKGSRPIDTSRLTKITKPGSIDSNNQLFAPGG 893
            KRR          G+  VD+GGWNTV  +K SR +D S+  KITKP +ID   QL     
Sbjct: 1022 KRR---------PGVQRVDEGGWNTVQGAKNSRVLDPSKFLKITKP-TIDEKIQLVPKAQ 1071

Query: 894  RLSWGKGSSGGSGAKPSDAASEAARPATSTLNRFSALQQAVPTEST-------DNRR-VV 945
              SWGKGSSGG+ A  +D    A R + S+LNRFSALQ   P+ ST       D+RR + 
Sbjct: 1072 LGSWGKGSSGGAKASETD----ALRSSASSLNRFSALQPPAPSGSTPSTPVEFDSRRTLT 1127

Query: 946  QRSSLSRERGEK-AGDRGDRLERSERGGDRGDRLDRARTPATKRSFSKEVEERSRERPSQ 1004
             R S+ RE+ +K       R     RGG   D LD           ++  EE+ RE    
Sbjct: 1128 SRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLD-----------NQSQEEQRREMLET 1176

Query: 1005 PEGLRKAASLTEDRDRGRDAVKREAALPPVSPL----KAALSEEELEKKSKAIIEEYLHL 1060
             + L     +  +         RE+A P +S +    KAALSEEELE+KSK+II+E+LH+
Sbjct: 1177 VKQLTGGVDVERNSTEAERNKTRESAKPEISAMSAHDKAALSEEELERKSKSIIDEFLHI 1236

Query: 1061 NDMKEAVQCVQELASPSLLFIFVRHGVESTLERSAIAREHMGQLLHQLLCAGHLSTAQYY 1120
            ND KEA+QCV+EL +  LL +FVR GVESTLERS I R+HMGQLL+QL+ +  LS   ++
Sbjct: 1237 NDFKEAMQCVEELNAQGLLHVFVRVGVESTLERSQITRDHMGQLLYQLVQSEKLSKQDFF 1296

Query: 1121 QGLYEILELAEDMEIDIPHVWLYLAELVTPILQEGGVPMGELFREITKPLRPLGKAASLL 1180
            +G  E LELA+DM IDIPH+WLYLAELVTP+L+EGG+ M EL  E +KPL P+G+A  LL
Sbjct: 1297 KGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLL 1356

Query: 1181 LEILGLLCKSMGPKKVGTLWREAGLSWKEFLPEGQDIGAFVAEQKVEYTLGE---ESEAP 1237
             EIL LLCK M  KKVG LWREA LSWK+FLPEG+D+  F+ EQK+++   +    SEA 
Sbjct: 1357 SEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDSPCSSEAL 1416

Query: 1238 GQRALPSEELNRQLEKLLKEGSSN-QRVFDWIEANLSEQQIVSNTLVRALMTAVCYSAII 1296
             ++ L +EEL ++LEKL+ E  +N +++FDW+EANL E Q+ S T +RALMTAVC +AII
Sbjct: 1417 SKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAII 1476

Query: 1297 FE-TPLRVDVAVLKARAKLLQKYL-CDEQKELQALYALQALVVTLEQPPNLLRMFFDALY 1354
             + +  RVD AV+K R  +L KYL  D +KELQALYALQA +V L+QP NLLRMFFD LY
Sbjct: 1477 ADSSTFRVDTAVIKQRVPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLY 1536

Query: 1355 DEDVVKEDAFYSWESSKDPAEQQGKGVALKSVTAFFKWLREAEEESDHN 1403
            DE+V+ EDAFY WESSKDPAEQ GKGVALKSVTAFF WLREAEEES+ N
Sbjct: 1537 DEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN 1585


>gi|110630018 eukaryotic translation initiation factor 4 gamma, 2
           isoform 2 [Homo sapiens]
          Length = 869

 Score =  196 bits (498), Expect = 1e-49
 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)

Query: 511 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 567
           G R  P+    T   +E +     + A  W P+      D       A+  +  D +FR+
Sbjct: 21  GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80

Query: 568 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 627
           VR ILNKLTP+ F +L  ++  + ++++  LKGVI LI +KA+ EP +S  YA +C  L 
Sbjct: 81  VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139

Query: 628 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679
           A   P  + P          +  FR+LL+++ Q EFE    + +V++K++  +       
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192

Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 733
               L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+  LL+          
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247

Query: 734 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 792
            E LECLC+++ T+G  LD E+AK  MDQYF +M  ++  K+  +RIRF+LQD ++LR  
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307

Query: 793 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 843
           +WVPR+   D GPKTI+QI ++A +++    I         SD    GP  PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359



 Score =  113 bits (282), Expect = 1e-24
 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)

Query: 1032 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1090
            P  +  K   S+EEL K ++ ++ EYL+  +  EAV  V+E+ +P   L   +   +  +
Sbjct: 492  PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 551

Query: 1091 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1150
            L+RS   +E    L+  L   G  ++  + Q    +L+    +E+DIP V  YLA+    
Sbjct: 552  LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 611

Query: 1151 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1210
             +    V + EL     +PL   G    L L  L  L K    + +  L++++ ++ ++ 
Sbjct: 612  AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 666

Query: 1211 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1269
            LPE         +Q  +  L E  E  G   L P  +L ++L K +K   S Q ++ WI+
Sbjct: 667  LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 717

Query: 1270 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1314
             N+S +  V    V  LMT+                  S+   +  L  +  +L +   +
Sbjct: 718  DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 777

Query: 1315 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1373
            +QK+L D    ++ ALYALQ        P  +L  FF   YD ++++E+AF +W+     
Sbjct: 778  MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 836

Query: 1374 AEQQGKGVALKSVTAFFKWLREAEEE 1399
             E  GKG AL  V  +  WL  AEEE
Sbjct: 837  QEFPGKGKALFQVNQWLTWLETAEEE 862


>gi|4503539 eukaryotic translation initiation factor 4 gamma, 2
           isoform 1 [Homo sapiens]
          Length = 907

 Score =  196 bits (498), Expect = 1e-49
 Identities = 128/353 (36%), Positives = 192/353 (54%), Gaps = 34/353 (9%)

Query: 511 GPRKEPRKIIATVLMTEDIKLNKAEKA--WKPSSKRTAADKDRGEEDADGSKTQD-LFRR 567
           G R  P+    T   +E +     + A  W P+      D       A+  +  D +FR+
Sbjct: 21  GSRGAPQHYPKTAGNSEFLGKTPGQNAQKWIPARSTRRDDNSAANNSANEKERHDAIFRK 80

Query: 568 VRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLM 627
           VR ILNKLTP+ F +L  ++  + ++++  LKGVI LI +KA+ EP +S  YA +C  L 
Sbjct: 81  VRGILNKLTPEKFDKLCLELLNVGVESKLILKGVILLIVDKALEEPKYSSLYAQLCLRL- 139

Query: 628 ALKVPTTEKPTV--------TVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679
           A   P  + P          +  FR+LL+++ Q EFE    + +V++K++  +       
Sbjct: 140 AEDAPNFDGPAAEGQPGQKQSTTFRRLLISKLQDEFENRTRNVDVYDKRENPL------- 192

Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHDE------ 733
               L EE EE R IA+ + LGNIKFIGEL KL ++ E+I+H C+  LL+          
Sbjct: 193 ----LPEE-EEQRAIAKIKMLGNIKFIGELGKLDLIHESILHKCIKTLLEKKKRVQLKDM 247

Query: 734 -ESLECLCRLLTTIGKDLDFEKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGS 792
            E LECLC+++ T+G  LD E+AK  MDQYF +M  ++  K+  +RIRF+LQD ++LR  
Sbjct: 248 GEDLECLCQIMRTVGPRLDHERAKSLMDQYFARMCSLMLSKELPARIRFLLQDTVELREH 307

Query: 793 NWVPRRG--DQGPKTIDQIHKEAEMEEHREHIKVQQLMAKGSDKRRGGPPGPP 843
           +WVPR+   D GPKTI+QI ++A +++    I         SD    GP  PP
Sbjct: 308 HWVPRKAFLDNGPKTINQIRQDA-VKDLGVFIPAPMAQGMRSDFFLEGPFMPP 359



 Score =  113 bits (282), Expect = 1e-24
 Identities = 107/386 (27%), Positives = 176/386 (45%), Gaps = 33/386 (8%)

Query: 1032 PPVSPLKAALSEEELEKKSKAIIEEYLHLNDMKEAVQCVQELASPS-LLFIFVRHGVEST 1090
            P  +  K   S+EEL K ++ ++ EYL+  +  EAV  V+E+ +P   L   +   +  +
Sbjct: 530  PAKTSKKPPPSKEELLKLTETVVTEYLNSGNANEAVNGVREMRAPKHFLPEMLSKVIILS 589

Query: 1091 LERSAIAREHMGQLLHQLLCAGHLSTAQYYQGLYEILELAEDMEIDIPHVWLYLAELVTP 1150
            L+RS   +E    L+  L   G  ++  + Q    +L+    +E+DIP V  YLA+    
Sbjct: 590  LDRSDEDKEKASSLISLLKQEGIATSDNFMQAFLNVLDQCPKLEVDIPLVKSYLAQFAAR 649

Query: 1151 ILQEGGVPMGELFREITKPLRPLGKAASLLLEILGLLCKSMGPKKVGTLWREAGLSWKEF 1210
             +    V + EL     +PL   G    L L  L  L K    + +  L++++ ++ ++ 
Sbjct: 650  AIISELVSISEL----AQPLES-GTHFPLFLLCLQQLAKLQDREWLTELFQQSKVNMQKM 704

Query: 1211 LPEGQDIGAFVAEQKVEYTLGEESEAPGQRAL-PSEELNRQLEKLLKEGSSNQRVFDWIE 1269
            LPE         +Q  +  L E  E  G   L P  +L ++L K +K   S Q ++ WI+
Sbjct: 705  LPE--------IDQNKDRML-EILEGKGLSFLFPLLKLEKELLKQIKLDPSPQTIYKWIK 755

Query: 1270 ANLSEQQIVSNTLVRALMTAVCY---------------SAIIFETPLRVDVAVLKARAKL 1314
             N+S +  V    V  LMT+                  S+   +  L  +  +L +   +
Sbjct: 756  DNISPKLHVDKGFVNILMTSFLQYISSEVNPPSDETDSSSAPSKEQLEQEKQLLLSFKPV 815

Query: 1315 LQKYLCDE-QKELQALYALQALVVTLEQPPNLLRMFFDALYDEDVVKEDAFYSWESSKDP 1373
            +QK+L D    ++ ALYALQ        P  +L  FF   YD ++++E+AF +W+     
Sbjct: 816  MQKFLHDHVDLQVSALYALQVHCYNSNFPKGMLLRFFVHFYDMEIIEEEAFLAWKED-IT 874

Query: 1374 AEQQGKGVALKSVTAFFKWLREAEEE 1399
             E  GKG AL  V  +  WL  AEEE
Sbjct: 875  QEFPGKGKALFQVNQWLTWLETAEEE 900


>gi|33386693 poly(A) binding protein interacting protein 1 isoform 2
           [Homo sapiens]
          Length = 400

 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)

Query: 505 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 564
           P+++ +    +P+ ++A VLM++ + +N  E      S       + G ED        L
Sbjct: 26  PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 79

Query: 565 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 619
              V+  LN LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   
Sbjct: 80  SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 139

Query: 620 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679
           A +C  L      + +      NFR+LLL RC+ E+E                       
Sbjct: 140 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 172

Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 727
               +K++  +  ++ R+R    + F+GEL+  L++           + +  + + +  L
Sbjct: 173 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 228

Query: 728 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 784
             N  +++L C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML 
Sbjct: 229 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 288

Query: 785 DVLDLRGSNW 794
            +++LR SNW
Sbjct: 289 KLVELRSSNW 298


>gi|17511255 poly(A) binding protein interacting protein 1 isoform 1
           [Homo sapiens]
          Length = 479

 Score = 80.9 bits (198), Expect = 8e-15
 Identities = 73/310 (23%), Positives = 141/310 (45%), Gaps = 57/310 (18%)

Query: 505 PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDL 564
           P+++ +    +P+ ++A VLM++ + +N  E      S       + G ED        L
Sbjct: 105 PQQNSESAMAKPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TL 158

Query: 565 FRRVRSILNKLT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAY 619
              V+  LN LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   
Sbjct: 159 SEYVQDFLNHLTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMG 218

Query: 620 ANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAE 679
           A +C  L      + +      NFR+LLL RC+ E+E                       
Sbjct: 219 ARLCNYLSHHLTISPQSG----NFRQLLLQRCRTEYE----------------------- 251

Query: 680 ERGRLKEELEEARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKL 727
               +K++  +  ++ R+R    + F+GEL+  L++           + +  + + +  L
Sbjct: 252 ----VKDQAAKGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNAL 307

Query: 728 LKNHDEESLECLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQ 784
             N  +++L C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML 
Sbjct: 308 FSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLL 367

Query: 785 DVLDLRGSNW 794
            +++LR SNW
Sbjct: 368 KLVELRSSNW 377



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 31/123 (25%), Positives = 42/123 (34%), Gaps = 20/123 (16%)

Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 32  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSRPGALPEQT 91

Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT---PATAPSATSPAQEEEMEEE 264
                 P + D  P    E    +    +AP  +   +   P   PS  S +  E  E+ 
Sbjct: 92  RPLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLMSKLSVNAPEFYPSGYSSSYTESYEDG 151

Query: 265 EEE 267
            E+
Sbjct: 152 CED 154


>gi|169212085 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 516

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 115 PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 173

Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 174 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 228

Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 229 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 284

Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 285 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 317

Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 318 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 377

Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 378 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 414



 Score = 30.8 bits (68), Expect = 9.6
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 69  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 128

Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 129 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 186


>gi|239752553 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 457

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 56  PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 114

Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 115 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 169

Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 170 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 225

Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 226 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 258

Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 259 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 318

Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 319 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 355



 Score = 30.8 bits (68), Expect = 9.6
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 10  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 69

Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 70  RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 127


>gi|89041275 PREDICTED: similar to poly(A) binding protein
           interacting protein 1 [Homo sapiens]
          Length = 488

 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 78/337 (23%), Positives = 145/337 (43%), Gaps = 66/337 (19%)

Query: 487 PPRGGPGGELPRGPAGLG---------PRRSQQGPRKEPRKIIATVLMTEDIKLNKAEKA 537
           P R  P G LP     L          P+++ +    +P+ ++A VL ++ + +N  E  
Sbjct: 87  PQRPSPPGALPEQTRSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSK-LSVNAPEFY 145

Query: 538 WKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNKLT--PQMFQQLMKQVTQL---AI 592
               S       + G ED            V+  LN LT  P  F+  ++Q  +     +
Sbjct: 146 PSGYSSSYTESYEVGCEDYPTPSEY-----VQDFLNHLTEQPGSFETEIEQFAETLNGCV 200

Query: 593 DTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPTVTVNFRKLLLNRCQ 652
            T++ L+ + +LI+++A S PNFS   A +C  L      + +      NFR+LLL RC+
Sbjct: 201 TTDDALQELAELIYQQATSIPNFSYMGARLCNYLSHHLTISPQSG----NFRQLLLQRCR 256

Query: 653 KEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELEEARDIARRRSLGNIKFIGELF-K 711
            E+E                           +K++  +  ++ R+R    + F+GEL+  
Sbjct: 257 TEYE---------------------------VKDQAAKGDEVTRKRFHAFVFFLGELYLN 289

Query: 712 LKM-----------LTEAIMHDCVVKLLKNHDEESLECLCRLLTTIGKDLDF---EKAKP 757
           L++           + +  + + +  L  N  +++L C  +LL   G  L+    EK K 
Sbjct: 290 LEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLICAVKLLKLTGSVLEDAWKEKGKM 349

Query: 758 RMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794
            M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 350 DMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 386



 Score = 30.8 bits (68), Expect = 9.6
 Identities = 30/118 (25%), Positives = 39/118 (33%), Gaps = 20/118 (16%)

Query: 165 PNGMVPSED-------------LEPEVESSPELAPPPACPSESPV----PIAPTAQPEEL 207
           PNG  P+E              L+P     P   PPP    E P     P  P A PE+ 
Sbjct: 41  PNGAGPAERARHQPPQPKAPGFLQPPPLRQPRTTPPPGAQCEVPASPQRPSPPGALPEQT 100

Query: 208 LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP---PTIPSATPATAPSATSPAQEEEME 262
            +    P + D  P    E    +    +AP     +    P   PS  S +  E  E
Sbjct: 101 RSLRAPPSSQDKIPQQNSESAMAKPQVVVAPVLRSKLSVNAPEFYPSGYSSSYTESYE 158


>gi|34452730 poly(A) binding protein interacting protein 1 isoform 3
           [Homo sapiens]
          Length = 367

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 72/300 (24%), Positives = 136/300 (45%), Gaps = 57/300 (19%)

Query: 515 EPRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRVRSILNK 574
           +P+ ++A VLM++ + +N  E      S       + G ED        L   V+  LN 
Sbjct: 3   KPQVVVAPVLMSK-LSVNAPEFYPSGYSSSYTESYEDGCEDYP-----TLSEYVQDFLNH 56

Query: 575 LT--PQMFQQLMKQVTQL---AIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMAL 629
           LT  P  F+  ++Q  +     + T++ L+ +++LI+++A S PNFS   A +C  L   
Sbjct: 57  LTEQPGSFETEIEQFAETLNGCVTTDDALQELVELIYQQATSIPNFSYMGARLCNYLSHH 116

Query: 630 KVPTTEKPTVTVNFRKLLLNRCQKEFEKDKDDDEVFEKKQKEMDEAATAEERGRLKEELE 689
              + +      NFR+LLL RC+ E+E                           +K++  
Sbjct: 117 LTISPQSG----NFRQLLLQRCRTEYE---------------------------VKDQAA 145

Query: 690 EARDIARRRSLGNIKFIGELF-KLKM-----------LTEAIMHDCVVKLLKNHDEESLE 737
           +  ++ R+R    + F+GEL+  L++           + +  + + +  L  N  +++L 
Sbjct: 146 KGDEVTRKRFHAFVLFLGELYLNLEIKGTNGQVTRADILQVGLRELLNALFSNPMDDNLI 205

Query: 738 CLCRLLTTIGKDLDF---EKAKPRMDQYFNQMEKIIKEKKTSSRIRFMLQDVLDLRGSNW 794
           C  +LL   G  L+    EK K  M++   ++E ++ +   S  ++ ML  +++LR SNW
Sbjct: 206 CAVKLLKLTGSVLEDAWKEKGKMDMEEIIQRIENVVLDANCSRDVKQMLLKLVELRSSNW 265


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 97/390 (24%), Positives = 140/390 (35%), Gaps = 83/390 (21%)

Query: 3    GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62
            GA T    TPP   GGL    +   P  AV+  P  +             GP  SP +  
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG------------GPATSPPKGA 1309

Query: 63   PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122
            P+ P+ TP PSP   PG+ P     + P  T                           P+
Sbjct: 1310 PTPPAATP-PSPKGSPGTPPPKGAPTPPAVT--------------------------PPS 1342

Query: 123  PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
            P   P L      SK  P +  S    + PTP A+       P  M P     P  +  P
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSK---EGPTPPAATPSHKGGP-AMTP-----PSPKRGP 1393

Query: 183  ELAPPPACP-SESPVPIAPTAQPEELL--NGAPSPPAVDLSPVSEPEEQAKEVTASMAP- 238
             +  P   P S + +P++P   P   +   GA +P   DL+P +      K+  A+ AP 
Sbjct: 1394 AIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPK 1453

Query: 239  --PTIPSAT-PATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEEL---LPPES 292
              P  PS+    T P+ T P+ +E    ++        +A    +  G   L   +P   
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSP 1513

Query: 293  TPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQP 352
              +PA  S   +  A T   +S    ++    L  KEA+                    P
Sbjct: 1514 KEVPATPSSRRDPIAPTATLLS----KKTPATLAPKEAL-------------------IP 1550

Query: 353  PAGSNPGPESEGSGVPPRPEEADETWDSKE 382
            PA + P P+   +   P P+EA  T  SKE
Sbjct: 1551 PAMTVPSPKK--TPAIPTPKEAPATPSSKE 1578



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 96/404 (23%), Positives = 137/404 (33%), Gaps = 63/404 (15%)

Query: 6    TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAII-----ADRPGLPGPEHSPSE 60
            T  +PTPP   G   P A        V + P +    +++      + P  P P+ +P+ 
Sbjct: 852  TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911

Query: 61   SQ-----------------PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103
            S                  P+SPSP  +P+P       P       P         +   
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPK----GGPATPSPKWAPTPPA 967

Query: 104  STPISRETGEPYRLSPE--PTPLAEPILEVEVTLSKPVPE-SEFSSSPLQAPTPLASHTV 160
            +TP S + G P   SP+  PTP A          + P P+    + SP  APTP A   V
Sbjct: 968  ATPPSPK-GGPATPSPKGAPTPPA---------ATPPSPKGGPATPSPKGAPTPPA---V 1014

Query: 161  EIHEPNGMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELL---NGAPSP 214
                P G  P+    P+  S+P  A PP+    P+ +P+P      P   L    G P+ 
Sbjct: 1015 TPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT 1073

Query: 215  PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 274
            P++       P   A    +    P  PS   A  P A +P   +        +      
Sbjct: 1074 PSLK----GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129

Query: 275  AGEAESEKGGEELLPPESTP-IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGD 333
            A    S KGG    PP+  P  PA    + +   AT      PK              G 
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT----PPPKGAPTTPAATPPSPKGG 1185

Query: 334  LLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRPE 372
            L     +  P  P      P G    P  +G     +  PP P+
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1229



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 100/447 (22%), Positives = 155/447 (34%), Gaps = 78/447 (17%)

Query: 3    GARTASTPTPPQTGGGLEPQAN-GETPQVAVIVRPDDRSQGAIIADRP----GLPGPEHS 57
            G  T    TP   GG   P +  G TP  A    P  +   A+    P     +P P+  
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAAT---PSHKGGPAMTPPSPKRGPAIPSPKGD 1401

Query: 58   PSESQ--PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP-----ISRE 110
            P+     P SP   P+     E  + P+   L+ P  T  +++ +   S P         
Sbjct: 1402 PTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461

Query: 111  TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPT----------------- 153
             G+P   +  P    EP    +V  S    ++  + +P+ APT                 
Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS 1521

Query: 154  ----PLASHTVEIHE--PNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEE- 206
                P+A     + +  P  + P E L P   + P     PA P+    P  P+++    
Sbjct: 1522 SRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581

Query: 207  -------LLNGAPSPPAVDLSP-VSEPEEQAKEVTASMAPPTIPS--ATPATAPSATSPA 256
                      GAPSP  + + P V+ P  +      ++ PP+     ATPA   + TSP 
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641

Query: 257  QEEEMEEEEEEEEGE--------AGEAGEAESEKGGEELL-------PPESTPI---PAN 298
                  ++                 +A +    K G   L        PESTPI   P  
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701

Query: 299  LSQNLEAAAATQVAVSV-PKRRRKIKELNKKEAVGDLLDAFKEAN-PAVPEVENQPPAGS 356
                 + ++AT   +   P  +   K      A   LL   K+++  A  +  +  P G 
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761

Query: 357  NPGPESEGS---------GVPPRPEEA 374
               PES+ S          V P+PE A
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESA 1788



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 86/378 (22%), Positives = 129/378 (34%), Gaps = 36/378 (9%)

Query: 3    GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62
            GA T    TPP   GG    +    P    +  P  +   A        P P+ + +   
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA------ATPFPKGASTPPA 1037

Query: 63   PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEES-TPISRETGEPYRLSPEP 121
             + PSP  SP+    P   P     ++P         S++ + TP +     P      P
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097

Query: 122  TPLAEPILEVEVTLSKPVPESEFSSSPLQ-APTPLASHTVEIHEPNGMVPSEDLEPEVES 180
            +P   P   +    + P P+   ++ P + APT  A+       P G + +    P+   
Sbjct: 1098 SPKGAP---MPPAATPPSPKGGLATPPHKGAPTTPAATP---PSPKGGLATP--PPKGAP 1149

Query: 181  SPELAPPP------ACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEEQAKEV 232
            +   A PP      A P     P  P A P     G   PSP     +P + P       
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---- 1205

Query: 233  TASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 292
               +A P+ P   P T P+AT P+ +  +      +      A    S KGG    PP+ 
Sbjct: 1206 KGGLATPS-PKGAP-TTPAATPPSPKGGL-ATPSPKGAPTTPAATPPSPKGGPATPPPKG 1262

Query: 293  TPI-PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 351
             P  PA    +L+   AT      P        +      G    +  +  P  P     
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNP----AVVTPPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 352  PPAGSNPGPESEGSGVPP 369
             P GS   P  +G+  PP
Sbjct: 1319 SPKGSPGTPPPKGAPTPP 1336



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 90/379 (23%), Positives = 119/379 (31%), Gaps = 61/379 (16%)

Query: 3    GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62
            GA T    TPP   GG    +    P       P  +         P  P P+ +P+   
Sbjct: 938  GAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGG-------PATPSPKGAPTPPA 990

Query: 63   PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122
             + PSP   P+     G+    AV                  TP           SP+ +
Sbjct: 991  ATPPSPKGGPATPSPKGAPTPPAV------------------TP----------PSPKGS 1022

Query: 123  PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
            P A P  +   T     P S    SP   P P  + T     P   +PS    P   S  
Sbjct: 1023 PAATPFPKGASTPPAATPPSP-KGSPAATPLPKGAPTT----PAATLPSPKGGPATPSLK 1077

Query: 183  ELAPPPACPSESPVPIAPTAQPEELLNGAPSPP-AVDLSP---VSEPEEQAKEVTASMAP 238
                PPA    SP     T  P+    GAP PP A   SP   ++ P  +    T +  P
Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPK----GAPMPPAATPPSPKGGLATPPHKGAPTTPAATP 1133

Query: 239  P-------TIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPE 291
            P       T P     T P+AT P+ +  +      +      A    S KGG     P+
Sbjct: 1134 PSPKGGLATPPPKGAPTTPAATPPSPKGGL-ATPPPKGAPTTPAATPPSPKGGLATPSPK 1192

Query: 292  STP-IPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVEN 350
              P  PA    + +   AT      PK              G L     +  P  P    
Sbjct: 1193 GAPTTPAATPPSPKGGLAT----PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 351  QPPAGSNPGPESEGSGVPP 369
              P G    P  +G+  PP
Sbjct: 1249 PSPKGGPATPPPKGAPTPP 1267



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 88/361 (24%), Positives = 124/361 (34%), Gaps = 67/361 (18%)

Query: 52   PGPEHSPSESQPSSPSPTPSPSPV---------LEPGSEPNLAVLSIPGDTMTTIQMSVE 102
            P   HSP+   P SP   P+PS V         L P   P  +V+++P         + +
Sbjct: 850  PATTHSPT---PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906

Query: 103  ESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI 162
            ++  +S  +  P +    P P   P                 S SP  APTP A+ T   
Sbjct: 907  QAPALSMTSSSPKKARATPAPKGIPA----------------SPSPKGAPTPPAA-TPPS 949

Query: 163  HEPNGMVPSEDLEPEVES----SPELAPPPACPSESPVPIAPT--------AQPEELLNG 210
             +     PS    P   +    SP+  P    P  +P P A T        A P     G
Sbjct: 950  PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP--KG 1007

Query: 211  APSPPAVDL-----SPVSEPEEQAKEVTASMAPPT---IPSATP-----ATAPSATSPAQ 257
            AP+PPAV       SP + P  +      +  PP+    P+ATP      T P+AT P+ 
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 258  EEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI-PANLSQNLEAAAATQVAVSVP 316
            +         +      A    S KGG     P+  P+ PA    + +   AT      P
Sbjct: 1068 KGG-PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 317  KRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEG-----SGVPPRP 371
                      K    G L     +  P  P      P G    P  +G     +  PP P
Sbjct: 1127 TTPAATPPSPK----GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182

Query: 372  E 372
            +
Sbjct: 1183 K 1183



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 55/248 (22%), Positives = 96/248 (38%), Gaps = 29/248 (11%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSES 61
            S  +T + PTP +       +     P V         S   ++   P +  P  SP E+
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP-PAVTSP--SPKEA 1613

Query: 62   QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121
             P+ P+ TP PSP   P +       + P  T ++++ S      ++ + G     + + 
Sbjct: 1614 -PTPPAVTP-PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKG 1671

Query: 122  TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181
             P  +    ++  L  P PE   S+  + APT     T               +    +S
Sbjct: 1672 LPAKKGPTALKEVLVAPAPE---STPIITAPTRKGPQT---------------KKSSATS 1713

Query: 182  PELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTI 241
            P + P P+  + S  P++ T  P  LL     P   D S  ++ ++ +      +APP  
Sbjct: 1714 PPICPDPSAKNGSKGPLS-TVAPAPLL-----PVQKDSSKTAKGKDASHSPKGPLAPPES 1767

Query: 242  PSATPATA 249
             ++TP TA
Sbjct: 1768 KASTPLTA 1775



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 87/364 (23%), Positives = 134/364 (36%), Gaps = 89/364 (24%)

Query: 46  ADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQM--SVEE 103
           AD  G+       + +  ++ SP    +  L P + P      +   T+TT+ +  +  E
Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHP------VKEGTLTTLPLVPTASE 706

Query: 104 STPISRETGEPYRLSPEPT--PLAEPILEVEVTLSKPVPESEFSSSP-----------LQ 150
           + P++         SP+ T  PLA  +L  E+  S P P    + +P             
Sbjct: 707 NCPVAP--------SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTS 758

Query: 151 APTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQ----PEE 206
           A  P+AS   E        P+ED      +S +        S SP+ ++ + Q    P +
Sbjct: 759 ALAPVASSPKEC-------PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTK 811

Query: 207 LLNGAPSPPAVDLS-PVSEPE-----------EQAKEVTASMAPPTIPSATPATAPSATS 254
             +  P  P  +LS PVS  E           + +K+  A+   PT PS   A  PSA +
Sbjct: 812 KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT 871

Query: 255 PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPA--NLSQNLEAAAATQVA 312
           P                        S KG    LPP+ TP P+  NL    E       A
Sbjct: 872 PL-----------------------SPKG--VTLPPKETPTPSVVNLPFPKEGP-----A 901

Query: 313 VSVPKRRRKIKELNKKEAVGDLLDAFK--EANPAVPEVENQPPAGSNPGPESEGSGVPPR 370
              PK+   +   +          A K   A+P+ P+    PPA + P P  +G    P 
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSP--KGGPATPS 958

Query: 371 PEEA 374
           P+ A
Sbjct: 959 PKWA 962



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 56/223 (25%), Positives = 78/223 (34%), Gaps = 51/223 (22%)

Query: 21   PQANGETPQVA-----VIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPV 75
            P++   TP  A     V+ +P+  S  A             SP  S P +PSP P+  P 
Sbjct: 1765 PESKASTPLTAAAFEKVLPKPESASVSAA-----------PSPPVSLPLAPSPVPTLPPK 1813

Query: 76   LE-PGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVT 134
             +   S P L VL  P   +       +E  P+         + PEP     P   V V 
Sbjct: 1814 QQFLPSSPGL-VLESPSKPLA--PADEDELLPL---------IPPEPISGGVPFQSVLVN 1861

Query: 135  LSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSES 194
            +  P       S+ +  PTP A   V  +       S+      ES PEL        E 
Sbjct: 1862 MPTP------KSAGIPVPTPSAKQPVTKNNKGSGTESD----SDESVPEL--------EE 1903

Query: 195  PVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 237
                  T Q  +L   A     +D  PVS+ ++   E  A  A
Sbjct: 1904 QDSTQATTQQAQLAAAA----EIDEEPVSKAKQSRSEKKARKA 1942


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 70/253 (27%), Positives = 101/253 (39%), Gaps = 18/253 (7%)

Query: 12  PPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP- 70
           P +T   L P +  +TP  ++   P +               P  +P    P  P+P P 
Sbjct: 511 PLETQSSLAPPSL-QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 71  --SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI 128
              PSP+  P  E   ++ + P      +      S P+      P      P P A P 
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALA-----SPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 129 LEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH---EPNGMVPSEDLEPEVESSPELA 185
           L +    + P P +    SPL  P+P A + + +H    P    PS  ++     SP  A
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF--SPP-A 681

Query: 186 PPPACPSESPVPIAPTAQPEELLNGAPSPPAVD-LSPVSEPEEQAKEVTAS--MAPPTIP 242
            PP  PS +P   AP +     L   PSPPA   +SP + P  QA    A+  +  P  P
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 243 SATPATAPSATSP 255
            A+P  +PSAT P
Sbjct: 742 PASPPMSPSATPP 754



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 75/252 (29%), Positives = 104/252 (41%), Gaps = 28/252 (11%)

Query: 8   STPTPPQTGGGLEPQANG-ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSP 66
           +TP P        P   G  +P ++ +  P  ++   +    P L  P  SP  S P SP
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL--PPLQAPP-SPPASPPLSP 644

Query: 67  SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAE 126
             TPSP            A  S P         S   S P+S     P   S  P  LA 
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAA 701

Query: 127 PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP 186
           P L+V  +     P S  ++ P QAP PLA+  +++       PS    P +  SP   P
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP------PSPPASPPM--SPSATP 753

Query: 187 PPACPSESPVPIAPTAQPEELLNGAPSPPA-VDLSPVSEPEEQAKEVTAS---MAPPTIP 242
           PP  P   P+  AP  Q        PSPPA + +SP+++P  QA    A+    A P+ P
Sbjct: 754 PPRVP---PLLAAPPLQVP------PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804

Query: 243 SATPATAPSATS 254
           ++ P  AP + S
Sbjct: 805 ASFPGQAPFSPS 816



 Score = 64.7 bits (156), Expect = 6e-10
 Identities = 69/251 (27%), Positives = 92/251 (36%), Gaps = 43/251 (17%)

Query: 48  RPGLPGPEHSPSE---SQPSSPSPTPSPSPVLEPGSEP----NLAVLSIPGDTMTTIQMS 100
           RP    P+  P +   S P+SP    S SP + P S P     L  LS          +S
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505

Query: 101 VEESTPISRETG-EPYRLSPEPTPLAEPILEVEVTL--------SKPVPESEFSSSPLQA 151
                P+  ++   P  L   P  L  P LE   +L        S P+      + P  A
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPA 565

Query: 152 PTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPA----CPSESPVPIAPTAQPEEL 207
           P PL +    +  P    PS    P  ++ P LA PP      P  SP+   P   P  L
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 208 ----LNGAPSPPAVD-LSPVSEPEEQAKE------------------VTASMAPPTIPSA 244
               L   PSPPA   LSP++ P  QA                    V A  +PP  P  
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685

Query: 245 TPATAPSATSP 255
           +P+  P + +P
Sbjct: 686 SPSATPPSQAP 696



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 64/221 (28%), Positives = 89/221 (40%), Gaps = 27/221 (12%)

Query: 58  PSESQPS--SPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPY 115
           P E+Q S   PS    P+ +  P  E   ++   P  T +    +    TP       P 
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP---PCPAPC 567

Query: 116 RLSPEPTPLAEPILEVEVTLSKPVPESE--FSSSPLQA-PTPLASHTVEIHEPNGMVPSE 172
            L   P+PL  P  E   +++ P P++    +S PLQ  P+P  S    +  P    P  
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS---PLATPPPQAPPX 624

Query: 173 DLEPEVESSPEL-APPPACPSESPVPIAPTAQPEELLNGA----PSPPA-VDLSPVSEPE 226
              P +++ P   A PP  P  +P P AP A    LL       PSPP     SP + P 
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 227 EQAKEVTASMAPPTI----------PSATPATAPSATSPAQ 257
                   S APP++          P A+P  +PSAT P Q
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 68/282 (24%), Positives = 98/282 (34%), Gaps = 57/282 (20%)

Query: 1   MSGARTASTPTP-------PQTGGGLEPQANGETPQVAVIVRPDDRS--QGAIIADRPGL 51
           +S A   ST  P       P  GGGL+              RP  RS    A     P  
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQ--------------RPASRSLSSSATPLSSPAR 254

Query: 52  PGPEHSPSESQPSSPS-PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 110
            GP    +   P+ PS P P     L P   P +     P        +    S+P++  
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRP---PQVT----PPRKDAAPALGPLSSSPLATP 307

Query: 111 TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP 170
           +    +  P P P            + P+P +   S PL  P PLA  +         +P
Sbjct: 308 SPSGTKARPVPPP---------DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358

Query: 171 SEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL----LNGAPSPPAVD----LSPV 222
           S    P  ++ P +  PP     S   I P   P  L    L   PSP A+      + +
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 223 SEPEEQA---------KEVTASMAPPTIPSATPATAPSATSP 255
             P  QA         ++  AS+  P+ P++TP  +P   +P
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 72/300 (24%), Positives = 94/300 (31%), Gaps = 54/300 (18%)

Query: 57   SPSESQPSSPSPTPSP-----------------------SPVLEPGSEPNLAVLSIPGDT 93
            SP  S P SPS TP P                       SP+ +P  +   A+ + P   
Sbjct: 740  SPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQA 799

Query: 94   MTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP- 152
            + +   S     P S     P      P P A P+L   +     VP S  +S  LQAP 
Sbjct: 800  LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPR 856

Query: 153  -TPLASHTVEIHEPN---GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELL 208
              P       +  P     + P     P    S  L+ P      S    + T+ PEE L
Sbjct: 857  RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-L 911

Query: 209  NGAPSPP--AVDLSPVSEPEEQAKEVTASMAPPTIPSA------TPATAPSATSPAQEEE 260
             G  S P      SP  + E  A    A    P  P A       P   P AT P   + 
Sbjct: 912  RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 971

Query: 261  MEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320
            +    E E  E+        + G          P P        A A    +   PK+ R
Sbjct: 972  LCTIYETEGPESATPAPGALDPG----------PSPGTSGGKAAAGAGAGASSRSPKQAR 1021



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 71/302 (23%), Positives = 112/302 (37%), Gaps = 56/302 (18%)

Query: 7   ASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ-PSS 65
           +S+ TP  +     P A G     A   +P  +   A+   +   P  + +P+     SS
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302

Query: 66  PSPTPSPSPV-LEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR---ETGEPYRLSPEP 121
           P  TPSPS     P   P+ A   +P     T+  S   +TP+         P  L   P
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPA----TLPPSPPLATPLPLAPPSPSAPPSLQTLP 358

Query: 122 TPLAEPILEVEVTLSKP---------------VPESEFSSSPLQAPTPLASHTVE----- 161
           +P A P  +   +++ P               VP S  S S    P+PLA  +++     
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 162 -------IHEPNGMVPSE-DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPS 213
                   H    M P +        S P   PP + P ++P+ +  +   +  L+ A S
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478

Query: 214 P--------PAVDLSPVSEPEEQAK---------EVTASMAPPTI--PSATPATAPSATS 254
           P        P   LS ++    QA          E  +S+APP++  P A+  T P    
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENL 538

Query: 255 PA 256
           P+
Sbjct: 539 PS 540



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 36/151 (23%), Positives = 57/151 (37%), Gaps = 14/151 (9%)

Query: 10  PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLP-GPEHSPSESQPSSPSP 68
           P+PP +  G  P +   +  ++ +  P  ++   + A    +P  P  SP+   P  P P
Sbjct: 801 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP-P 859

Query: 69  TPSPSP---------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR-ETGEPYRLS 118
           TP P            L PG  P  +    P  T++   ++   S+  S  E    Y   
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPS--RSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 917

Query: 119 PEPTPLAEPILEVEVTLSKPVPESEFSSSPL 149
           PE    A P  + E+    P   S   + PL
Sbjct: 918 PEGGAAASPPPDAELAACHPAAWSRGPAPPL 948


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 60/257 (23%), Positives = 92/257 (35%), Gaps = 17/257 (6%)

Query: 8    STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67
            +TP+PP T     P     +P ++    P   +  +     P  P    SP  +  ++P 
Sbjct: 1436 TTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495

Query: 68   PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP---TPL 124
            PT +PSP       P    ++ P  T TT+  +   S P +  T  P   +P P   TP+
Sbjct: 1496 PTTTPSP-------PTTTPITPPAST-TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547

Query: 125  AEPILEVEV---TLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181
              P     +   T   P P +  +  P   P+P  + T          P     P   ++
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT 1607

Query: 182  PELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPAVDLSPVSEPEEQAKEVTASMAP 238
                PPP      P   PI P      L     PSPP    +        +   T + +P
Sbjct: 1608 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSP 1667

Query: 239  PTIPSATPATAPSATSP 255
            P   + TP    + +SP
Sbjct: 1668 PITTTTTPPPTTTPSSP 1684



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 64/246 (26%), Positives = 85/246 (34%), Gaps = 34/246 (13%)

Query: 6    TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65
            T +T TPP T     P     TP  +    P               P    SP  +  ++
Sbjct: 1527 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1571

Query: 66   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125
            P PT +PSP       P     S P  T TT   +   S P +  T  P   +P P P  
Sbjct: 1572 PPPTTTPSP-------PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTT 1623

Query: 126  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185
             PI     T + P P +  S  P    TP  + T          P     P    +    
Sbjct: 1624 TPITPPTSTTTLP-PTTTPSPPPTTTTTPPPTTTPS--------PPTTTTPSPPITTTTT 1674

Query: 186  PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSAT 245
            PPP     SP+   P+  P       PSP     SP++     +   T S  P T+ + +
Sbjct: 1675 PPPTTTPSSPITTTPS--PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPS 1732

Query: 246  PATAPS 251
            P T PS
Sbjct: 1733 PTTTPS 1738



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 65/260 (25%), Positives = 87/260 (33%), Gaps = 19/260 (7%)

Query: 44   IIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103
            I    P    P   P+ +    P+ TPSP P     + P     S P  T TT   +   
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSP-PTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 104  STPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIH 163
            S PIS  T  P   +P P     P        + P P +  +++P    TP    T  I 
Sbjct: 1455 SPPISTTTTPPPTTTPSP-----PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509

Query: 164  EPNGMVPSEDLEPEVESSP----ELAPPPACPSESP--VPIAPTAQPEEL-LNGAPSPPA 216
             P     +  L P    SP       PPP      P   PI P      L     PSPP 
Sbjct: 1510 PP---ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1566

Query: 217  VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 276
               +        +   T + +PPTI + TP   P  T+P+               +    
Sbjct: 1567 TTTTTPPPTTTPSPPTTTTPSPPTITTTTP---PPTTTPSPPTTTTTTPPPTTTPSPPTT 1623

Query: 277  EAESEKGGEELLPPESTPIP 296
               +       LPP +TP P
Sbjct: 1624 TPITPPTSTTTLPPTTTPSP 1643



 Score = 55.1 bits (131), Expect = 5e-07
 Identities = 52/218 (23%), Positives = 75/218 (34%), Gaps = 20/218 (9%)

Query: 8    STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67
            +TP+PP T     P     +P       P        I      P    SP  +  ++P 
Sbjct: 1560 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPT------ITTTTPPPTTTPSPPTTTTTTPP 1613

Query: 68   PTPSPSP-----VLEPGSE---PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 119
            PT +PSP     +  P S    P     S P  T TT   +   S P +     P   + 
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673

Query: 120  EPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVE 179
             P P   P   +  T   P P +   ++P    TP +  T      +   PS        
Sbjct: 1674 TPPPTTTPSSPITTT---PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT 1730

Query: 180  SSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 217
             SP   P P   + + +P   T+ P   L   P PP++
Sbjct: 1731 PSPTTTPSPPTTTMTTLPPTTTSSP---LTTTPLPPSI 1765



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 67/268 (25%), Positives = 95/268 (35%), Gaps = 43/268 (16%)

Query: 6    TASTPTPPQTGGGLEPQANGETP-QVAVIVRPDDRSQGA-------IIADRPGLPGPEHS 57
            T  TPTP  TG     Q    TP      V P     G        I       P P  +
Sbjct: 4067 TTVTPTPTPTG----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4122

Query: 58   PSESQPSSP-------SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRE 110
             +++  ++P       +PTP+P+    P + P     ++   T T        +TPI+  
Sbjct: 4123 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTT 4181

Query: 111  TGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP 170
            T     ++P PTP          T + P+ E   S+ P ++ TP  S +           
Sbjct: 4182 T----TVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS--------- 4228

Query: 171  SEDLEPEVESSPELAP-PPACPSESPVPIAPTAQPEELLNG--APSPPAVDLSPVSEPEE 227
                 P  ES+  L+  PPA    S  P +    P     G     PP+   SP   P  
Sbjct: 4229 ----SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR 4284

Query: 228  QAKEVTASMAPPTIPSATPATAPSATSP 255
                 T S + PT PS    T  SA +P
Sbjct: 4285 GT--TTGSSSAPT-PSTVQTTTTSAWTP 4309



 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 57/214 (26%), Positives = 74/214 (34%), Gaps = 34/214 (15%)

Query: 6    TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65
            T +T TPP T     P     TP  +    P               P    SP  +  ++
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLP---------------PTTTPSPPPTTTTT 1650

Query: 66   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125
            P PT +PSP       P     S P  T TT   +   S+PI+     P      P+P  
Sbjct: 1651 PPPTTTPSP-------PTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703

Query: 126  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185
             P   +  T +   P S  + SP        S T     P   + +  L P   SSP L 
Sbjct: 1704 TPSSPITTTTT---PSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTT--LPPTTTSSP-LT 1757

Query: 186  PPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219
              P  PS +P    PT  P       P+ P V L
Sbjct: 1758 TTPLPPSITP----PTFSP--FSTTTPTTPCVPL 1785



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 62/280 (22%), Positives = 94/280 (33%), Gaps = 54/280 (19%)

Query: 6    TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS 65
            T  TPTP  TG    P  +  T  +A +   +              P PE S  ++  S+
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN--------------PPPESSTPQTSRST 4227

Query: 66   PSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLA 125
             SP    + +L             P   MT+       + P +   G  + LSP P+   
Sbjct: 4228 SSPLTESTTLLSTLP---------PAIEMTSTAPPSTPTAPTTTSGG--HTLSPPPSTTT 4276

Query: 126  EPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELA 185
             P          P   +   SS    P+ + + T     P    P+    P +  +  L 
Sbjct: 4277 SPP-------GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPT---PTPLSTPSIIRTTGLR 4326

Query: 186  PPPA----CPSESPVPIAPTAQPEELLNGAPSPPAV----DLSPVSE------PEEQAKE 231
            P P+    C   +    AP    EE+ NG            LS   E      P   +  
Sbjct: 4327 PYPSSVLICCVLNDTYYAPG---EEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPT 4383

Query: 232  VTASMAPPTI--PSATPATAPSATSPAQEEEMEEEEEEEE 269
             T S + PT   PS+TP+     T P +  + +   +E E
Sbjct: 4384 PTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENE 4423


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)

Query: 27  TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 86
           +P ++ +  P  ++  A+    P L  P  SP  S P SP  TPSP            A 
Sbjct: 383 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 439

Query: 87  LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 146
            S P         S   S P+S     P   S  P  LA P L+V  +     P S  ++
Sbjct: 440 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 496

Query: 147 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 200
            P QAP PLA+  +++ +P    P     P +++ P  +PP + P ++P      +P++P
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 554

Query: 201 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 241
            A P           LL   PSPPA           +P  +       +T ++A  PP  
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614

Query: 242 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 297
           PS +P++  S    A          EE       G     +GG    PP    +    PA
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 669

Query: 298 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 355
             S+      A + A   P            + +  + +    + A PA   ++  P  G
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729

Query: 356 SNPGPESEGSG 366
           ++ G  + G+G
Sbjct: 730 TSGGKAAAGAG 740



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 66/272 (24%), Positives = 91/272 (33%), Gaps = 33/272 (12%)

Query: 6   TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS---PSESQ 62
           T  TP+P               P+ A   RP           RP   GP  S    SE  
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARP-----------RPPTEGPRKSVSSASEHS 216

Query: 63  PSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121
            + PSP     P    G + P    LS     +++   S   +    R    P +  P+ 
Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 276

Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVP-SEDLEPEVES 180
                P                 SSSPL  P+P A+   +        P S  L  ++ +
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336

Query: 181 SPELAPPP--ACPSESPVPIAPTAQPEELLNGAPSP---------PAVDLSPVSEPEEQA 229
              LAPP   A PS   +P  P   P +      SP         P+  LSP++ P  QA
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 230 KE------VTASMAPPTIPSATPATAPSATSP 255
                   + A  +PP  P  +P   PS  +P
Sbjct: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAP 428



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%)

Query: 8   STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67
           S P  P       P A+   P V+    P  ++  ++ A  P L  P  SP  S P SPS
Sbjct: 441 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 494

Query: 68  PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 117
            TP   +P P       + +P  +   A+ + P   + +   S     P S     P   
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554

Query: 118 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 172
              P P A P+L   +     VP S  +S  LQAP   P       +  P     + P  
Sbjct: 555 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611

Query: 173 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 230
              P    S  L+ P      S    + T+ PEE L G  S P      SP  + E  A 
Sbjct: 612 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 666

Query: 231 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 284
              A    P  P A       P   P AT P   + +    E E  E+        + G 
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 725

Query: 285 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320
                    P P        A A    +   PK+ R
Sbjct: 726 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 752


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 90/371 (24%), Positives = 140/371 (37%), Gaps = 44/371 (11%)

Query: 27  TPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAV 86
           +P ++ +  P  ++  A+    P L  P  SP  S P SP  TPSP            A 
Sbjct: 344 SPPLSPLATPPPQAPPALAL--PPLQAPP-SPPASPPLSPLATPSPQAPNALAVHLLQAP 400

Query: 87  LSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSS 146
            S P         S   S P+S     P   S  P  LA P L+V  +     P S  ++
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPASPPMSPSAT 457

Query: 147 SPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP------VPIAP 200
            P QAP PLA+  +++ +P    P     P +++ P  +PP + P ++P      +P++P
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP--SPPASFPGQAPFSPSASLPMSP 515

Query: 201 TAQP---------EELLNGAPSPPAVDL--------SPVSEPEEQAKEVTASMA--PPTI 241
            A P           LL   PSPPA           +P  +       +T ++A  PP  
Sbjct: 516 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 242 PSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI----PA 297
           PS +P++  S    A          EE       G     +GG    PP    +    PA
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPPPDAELAACHPA 630

Query: 298 NLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF--KEANPAVPEVENQPPAG 355
             S+      A + A   P            + +  + +    + A PA   ++  P  G
Sbjct: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690

Query: 356 SNPGPESEGSG 366
           ++ G  + G+G
Sbjct: 691 TSGGKAAAGAG 701



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 65/261 (24%), Positives = 90/261 (34%), Gaps = 41/261 (15%)

Query: 6   TASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS---PSESQ 62
           T  TP+P               P+ A   RP           RP   GP  S    SE  
Sbjct: 159 TPGTPSPAMARRSRAAGTEVGLPRPAPSARP-----------RPPTEGPRKSVSSASEHS 207

Query: 63  PSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 121
            + PSP     P    G + P    LS     +++   S   +    R    P +  P+ 
Sbjct: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267

Query: 122 TPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESS 181
                P                 SSSPL  P+P A             PS    P +++ 
Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP------------PSPSAPPSLQTL 315

Query: 182 PELAPPPACPSESPVPI-APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE------VTA 234
           P  +PP   PS++   + +PT Q        PSPP   LSP++ P  QA        + A
Sbjct: 316 P--SPPATPPSQATTSLGSPTLQATHSF--LPSPP---LSPLATPPPQAPPALALPPLQA 368

Query: 235 SMAPPTIPSATPATAPSATSP 255
             +PP  P  +P   PS  +P
Sbjct: 369 PPSPPASPPLSPLATPSPQAP 389



 Score = 47.8 bits (112), Expect = 8e-05
 Identities = 83/336 (24%), Positives = 112/336 (33%), Gaps = 47/336 (13%)

Query: 8   STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67
           S P  P       P A+   P V+    P  ++  ++ A  P L  P  SP  S P SPS
Sbjct: 402 SPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPSLAA--PPLQVPP-SPPASPPMSPS 455

Query: 68  PTP---SPSP-------VLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRL 117
            TP   +P P       + +P  +   A+ + P   + +   S     P S     P   
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515

Query: 118 SPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN---GMVPSE 172
              P P A P+L   +     VP S  +S  LQAP   P       +  P     + P  
Sbjct: 516 LATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572

Query: 173 DLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP--AVDLSPVSEPEEQAK 230
              P    S  L+ P      S    + T+ PEE L G  S P      SP  + E  A 
Sbjct: 573 PPPPSRSPSSTLSGPDLAGHSS----SATSTPEE-LRGYDSGPEGGAAASPPPDAELAAC 627

Query: 231 EVTASMAPPTIPSA------TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGG 284
              A    P  P A       P   P AT P   + +    E E  E+        + G 
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG- 686

Query: 285 EELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRR 320
                    P P        A A    +   PK+ R
Sbjct: 687 ---------PSPGTSGGKAAAGAGAGASSRSPKQAR 713



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 63/264 (23%), Positives = 93/264 (35%), Gaps = 53/264 (20%)

Query: 42  GAIIADRPGLPGPEHSP-----SESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDT-MT 95
           GA I +     GP  +         + + P+   SP PV  PG        + PG     
Sbjct: 67  GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGT---TRPGPLGQK 123

Query: 96  TIQMSVEESTPISRETGEPYRLSPE---------PTP-LAEPILE-------VEVTLSKP 138
            +++S EE+    + T  P R +           PTP    P +         EV L +P
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183

Query: 139 VPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEV--------------ESSPEL 184
            P +     P + P    S   E H      P+    P                 ++P  
Sbjct: 184 APSAR-PRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241

Query: 185 APPPACPSESPVPIAPT--AQP-----EELLNGAPSPPAVDLSPVSEPEEQAKEVTASMA 237
           +P  + PS    P AP   +QP     + L     +PP  D +P   P   +   T S +
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301

Query: 238 PPTIPSATPA----TAPSATSPAQ 257
            P  PSA P+     +P AT P+Q
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQ 325


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 71.6 bits (174), Expect = 5e-12
 Identities = 99/383 (25%), Positives = 140/383 (36%), Gaps = 69/383 (18%)

Query: 11  TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGP---EHSPS-----ESQ 62
           +PP+ G         + P    +        G + + +P  PGP   E  P      + +
Sbjct: 373 SPPEPG-----DTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLE 427

Query: 63  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122
           P   +P     P+L P   P  + LS P            E +P S    E  RLSP P 
Sbjct: 428 PQLEAPLNEEMPLLPP---PEESPLSPP-----------PEESPTSPPP-EASRLSPPPE 472

Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPT--PLASHTVEIHEPNGMVPSEDLEPEVES 180
            L    L   + LS+P+ ES  S  P ++P   P  S      E + + P E+  P    
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532

Query: 181 SPELAPPP-ACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPP 239
              L+PPP A P   P   +P + P E L  +P P A  LSP   PEE      + M+PP
Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP--PPEE------SPMSPP 584

Query: 240 TIPSATPATAPSATS----PAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 295
             P  +P + P   S    P +E  +    EE            S        PPE +P+
Sbjct: 585 --PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSP-------PPEDSPM 635

Query: 296 PANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQP--- 352
                    +    +  +S P    ++  L     V   L    E +P  P  E  P   
Sbjct: 636 ---------SPPPEESPMSPPPEVSRLSPL----PVVSRLSPPPEESPLSPPPEESPTSP 682

Query: 353 -PAGSNPGPESEGSGVPPRPEEA 374
            P  S   P  E S   P PE++
Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDS 705



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 80/345 (23%), Positives = 128/345 (37%), Gaps = 37/345 (10%)

Query: 55  EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT--TIQMSVEESTPISRETG 112
           +H+P  S+ S P P  +P+       EP+   ++  G         M  +E  P+  E  
Sbjct: 364 QHTPVCSRFSPPEPGDTPT------DEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK 417

Query: 113 EPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSE 172
              +   +  P  E  L  E+ L  P  ES  S  P ++PT        +  P   +P+ 
Sbjct: 418 PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPAS 477

Query: 173 DL---------------EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAV 217
            L                P  E SP L+PPP     SP+  +P + PEE    +P  PA+
Sbjct: 478 PLPEALHLSRPLEESPLSPPPEESP-LSPPPESSPFSPLEESPLSPPEE----SPPSPAL 532

Query: 218 DLSPVSEPEEQA------KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271
           + +P+S P E +      +E   S  P  +P++ P  A   + P +E  M    EE    
Sbjct: 533 E-TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591

Query: 272 AGEAGEAESEKGGEELL--PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKE 329
                        E  L  PPE +P+      +  +       +S P     +    +  
Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651

Query: 330 AVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEA 374
            +  L    + + P      + PP  S   P  E S + P PE++
Sbjct: 652 RLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS 696



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 100/392 (25%), Positives = 139/392 (35%), Gaps = 44/392 (11%)

Query: 9   TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS----PSESQPS 64
           T   P+  G L+ +A    P     V+ + + +  +  + P LP PE S    P E  P+
Sbjct: 402 TSMQPKEPGPLQCEAK---PLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPT 458

Query: 65  SPSPTP---SPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVE-------ESTPISRETGE 113
           SP P     SP P   P S  P    LS P +         E       ES+P S     
Sbjct: 459 SPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEES 518

Query: 114 PYRLSPEPTPLAEPILEVEVT-------LSKPVPESEFSSSPLQAPTPLASHTVEIHEPN 166
           P  LSP       P LE  ++       LS P  ES  S  P + PT        +  P 
Sbjct: 519 P--LSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPP 576

Query: 167 GMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-- 224
              P   + P  E SP   PP A     P   +P + P E    +P P A  LSP  E  
Sbjct: 577 EESP---MSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633

Query: 225 PEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEE--MEEEEEEEEGEAGEAGEAESEK 282
           P     E +    PP +   +P    S  SP  EE       EE       EA       
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP-- 691

Query: 283 GGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEAN 342
                 PPE +P       +  +       +S+P     +  L ++  +    +     +
Sbjct: 692 ------PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLS 744

Query: 343 PAVPEVENQP-PAGSNPGPESEGSGVPPRPEE 373
           P   E    P P   +  P++E   + P+PEE
Sbjct: 745 PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEE 776



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 87/304 (28%), Positives = 118/304 (38%), Gaps = 33/304 (10%)

Query: 9   TPTPPQTGGGLEPQANGETPQVAVIVRPD--DRSQGAIIADRPGLPGPEHSPSESQPSSP 66
           +P  P     L      E+P + +   P    RS+G  ++ RP  P     P E   S  
Sbjct: 705 SPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764

Query: 67  SPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP------ISRETGEPYRLSPE 120
           +  P  SP  E   EP L   ++P +   + Q      +P      +S +T EP+ LSP 
Sbjct: 765 AEEPHLSPQPE---EPCLC--AVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH-LSPV 818

Query: 121 PTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVES 180
           P    EP L  +   S   P+SE    P  +P P  SH     E   + P  +  PE   
Sbjct: 819 PE---EPCLSPQPEESHLSPQSE---EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872

Query: 181 ---SPE---LAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTA 234
              +PE   L PPP  PS SP+   P          +P P  + LSP  EP    + +  
Sbjct: 873 QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPP 932

Query: 235 SMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTP 294
              PP +     A AP A SP  E E         G  G++ + ES      L  P S P
Sbjct: 933 DPLPPPLSPIITAAAPPALSPLGELEY------PFGAKGDS-DPESPLAAPILETPISPP 985

Query: 295 IPAN 298
             AN
Sbjct: 986 PEAN 989



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 68/298 (22%), Positives = 108/298 (36%), Gaps = 31/298 (10%)

Query: 96  TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPL 155
           TI+   E+ TP+      P    P  TP  EP         +P      S  P + P PL
Sbjct: 357 TIRSVAEQHTPVCSRFSPP---EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKE-PGPL 412

Query: 156 ASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 215
                 + +    +  +   P  E  P L PP   P   P   +PT+ P E    +P P 
Sbjct: 413 QCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPE 472

Query: 216 AVDLSPVSEPEEQAKEVTAS-MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGE 274
            +  SP+ E    ++ +  S ++PP  P  +P + P  +SP    E       EE     
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPP--PEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530

Query: 275 AGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI------------ 322
           A E           PPE++P+     ++  +    ++  S P    ++            
Sbjct: 531 ALETPLSP------PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584

Query: 323 ---KELNKKEAVGDLLDAFKEANPAVPEVE---NQPPAGSNPGPESEGSGVPPRPEEA 374
                ++       L   F+E+  + P  E   + PP  S   P  E S + P PEE+
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 100/401 (24%), Positives = 142/401 (35%), Gaps = 52/401 (12%)

Query: 9   TPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP---------- 58
           +P P ++     P+++  +P     + P + S  +   + P  P PE SP          
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPL 554

Query: 59  ---SESQPSSP-------SPTP-----SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE 103
               E  P+SP       SP P     SP P   P S P  A    P    + +    EE
Sbjct: 555 SPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEE 614

Query: 104 STPISRETGEPYRLSPEP--TPLAEPILEVEVTLSKPVPESEFSSSPLQA---PTPLASH 158
           S P+S    E  RLSP P  +P++ P    E  +S P   S  S  P+ +   P P  S 
Sbjct: 615 S-PLSPPP-EASRLSPPPEDSPMSPP--PEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670

Query: 159 TVEIHEPNGMVPSED---LEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPP 215
                E +   P  +   L P  E SP   PP   P+  P        PE+ L   P   
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPP--------PEDSLMSLPLEE 722

Query: 216 AVDLSPVSEPEEQAKEVTASMAP-PTIPSATPATAPSATSPAQEEEMEEEEEEEE--GEA 272
           +  L    EP+   +     ++P P  P  +P       SP  EE     + EE      
Sbjct: 723 SPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782

Query: 273 GEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVG 332
            E      +  G  L P    P   +LS   E    + V        +  +     ++  
Sbjct: 783 PEEPHLSPQAEGPHLSP---QPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEE 839

Query: 333 DLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEE 373
             L    E +   PE+E +PP    P    E  G  P PEE
Sbjct: 840 PCLSPRPEESHLSPELE-KPPLSPRPEKPPEEPGQCPAPEE 879



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 60/266 (22%), Positives = 92/266 (34%), Gaps = 37/266 (13%)

Query: 6    TASTPTPPQTGGGLEPQANG-----ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSE 60
            TA   +  Q G G   +A+        P V++  +P   +Q  +   +P L  P  + + 
Sbjct: 4110 TAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTG 4169

Query: 61   SQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSP 119
             QP      P P PVL+ G   P + ++   G     +Q  + ++  +         LSP
Sbjct: 4170 PQP------PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR-------HLSP 4216

Query: 120  EPTPLAEPIL-------EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP-NGMVPS 171
            +     + +L          V  + P  E    +SPLQ              P  G +  
Sbjct: 4217 QQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276

Query: 172  EDLEPEVESSPELAPPPACPSESPV--PIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 229
                P  +  P L  PP   S  PV  P+ PT          PS P     P   P   +
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTP--------PPSSPQEPKRPSQLPSPSS 4328

Query: 230  KEVTASMAPPTIPSATPATAPSATSP 255
            +  T +  PPT P       P+   P
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQGPTLEPP 4354



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 101/416 (24%), Positives = 135/416 (32%), Gaps = 108/416 (25%)

Query: 10   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69
            P P  TG   +P      P +    RP     G      PG P         QPS+P P 
Sbjct: 2198 PYPSPTGAPAQP------PMLGASSRPGAGQPGEFHTTPPGTP-------RHQPSTPDPF 2244

Query: 70   PSPS-PVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPI 128
              P  P L+     NLAV   PG                  +  EP  LSP P   +   
Sbjct: 2245 LKPRCPSLD-----NLAVPESPGVG--------------GGKASEPL-LSPPPFGESRKA 2284

Query: 129  LEV---EVTLSKP---VPESEFSSSP----------LQAP-------TPLASHTVEIHEP 165
            LEV   E+  S P    P   F  SP          L+ P       TP AS  VE   P
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ-VEPQSP 2343

Query: 166  N-GMVPSED-----LEPEVESSPEL----------APPPACPSESPVP------IAPTAQ 203
              G+ P E      L P   S P++          A PP  P   P P      + P + 
Sbjct: 2344 GLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSL 2403

Query: 204  PEELLNGAPSPP---AVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQE-- 258
            P +  +  P+ P   +   SP++     A+    S   P   S  P + P +   +++  
Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPF 2463

Query: 259  ----EEMEEEEEEEEGEAGEAGEAESEKGGEELLPPES------TPIPANLSQNLEAAAA 308
                +    +  E   +AG         GG     P          +P+    N   +  
Sbjct: 2464 APLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPG 2523

Query: 309  TQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSN----PGP 360
            T   V  P   R        +AVG+         P VP+    PP G N    PGP
Sbjct: 2524 TGAFVGTPSPMR----FTFPQAVGE-----PSLKPPVPQPGLPPPHGINSHFGPGP 2570



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 81/343 (23%), Positives = 119/343 (34%), Gaps = 59/343 (17%)

Query: 3    GARTASTPTPPQTGGGLE------PQANGETPQVA--VIVRPDDRS-----QGAIIADRP 49
            GA+  S P  P     LE      P+AN   P+    +I+ P   S        ++   P
Sbjct: 962  GAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021

Query: 50   GLPGP--EHS--PSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST 105
                P  +HS  P  S PS  SP   P  V  P S P   V+ +  D     +M  E+ +
Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLS-PIGKVVGV-SDEAELHEMETEKVS 1079

Query: 106  PISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEP 165
                   EP   SP P+P+ +    +      P P  +  S   +   PL        +P
Sbjct: 1080 EPECPALEPSATSPLPSPMGD----LSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQP 1135

Query: 166  NGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTA------------QPEELLNGAPS 213
                    L  E++ SP L  P      +P+ + P              Q E     AP+
Sbjct: 1136 EPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPT 1195

Query: 214  PPAVDLSPVSEPEEQAKEVTASM----APPTIPSATPATAPSAT---------SPAQEE- 259
            PP +  S +        +  AS     + P + S  P    S +         SPA++E 
Sbjct: 1196 PPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEG 1255

Query: 260  ----------EMEEEEEEEEGEAGEAGEAESEKGGEELLPPES 292
                      E ++    + G A   G+AE EKG     P  S
Sbjct: 1256 SLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARS 1298



 Score = 38.9 bits (89), Expect = 0.035
 Identities = 28/85 (32%), Positives = 36/85 (42%), Gaps = 21/85 (24%)

Query: 185  APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEV-TASMAPPTIPS 243
            APPP  PS  P P+AP                   SP S P E   E+ T  +A P +PS
Sbjct: 4908 APPPEEPSPPPSPLAP-------------------SPASPPTEPLVELPTEPLAEPPVPS 4948

Query: 244  ATP-ATAPSATSPAQEEEMEEEEEE 267
              P A++P +  P       EE E+
Sbjct: 4949 PLPLASSPESARPKPRARPPEEGED 4973



 Score = 37.7 bits (86), Expect = 0.078
 Identities = 95/415 (22%), Positives = 137/415 (33%), Gaps = 86/415 (20%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPD-DRSQGAIIADRPGLPGPEHSPSE 60
            SG  T STPT P T G    + +G +     + R + D   G +    P L    + P+ 
Sbjct: 1976 SGGTTPSTPTTPTTEG----EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNL 2031

Query: 61   SQ--PSSPS------------PTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEEST- 105
             Q  P   S            P    +P L+   +   A            Q++ +    
Sbjct: 2032 KQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVG 2091

Query: 106  PISRETGEP---YRLSPEPTPLAEPILEVEVTL------------------------SKP 138
             I+R+T  P    R+ P+P  L  P      T+                        S P
Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP 2151

Query: 139  VPESE---FSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESP 195
             P+S    F   P Q P  + S      +P G+ P+  LEP   ++P   PP   P+ +P
Sbjct: 2152 GPDSPGELFLKLPPQVPAQVPSQ-----DPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206

Query: 196  VPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255
                  AQP  L  GA S P        +P E            T P  TP   PS   P
Sbjct: 2207 ------AQPPML--GASSRPG-----AGQPGEF----------HTTPPGTPRHQPSTPDP 2243

Query: 256  AQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSV 315
              +      +     E+   G     K  E LL    +P P   S+        ++  S 
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVG---GGKASEPLL----SPPPFGESRKALEVKKEELGASS 2296

Query: 316  PKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPR 370
            P             + G  L   +   P V +    P A S   P+S G G+ P+
Sbjct: 2297 PSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQ 2350



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 67/307 (21%), Positives = 100/307 (32%), Gaps = 59/307 (19%)

Query: 10   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQG-AIIADRPGLPGPEHSPSESQPSSPSP 68
            P PP++   L P++    P   V   P  +S   + +  RP L      PS   P   SP
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP-LSAEAFCPSPVTPRFQSP 2447

Query: 69   TPSPSPVLEPGSEPNLAVL------------------------------SIPGDTMTTIQ 98
             P   P   P S    A L                              ++P      + 
Sbjct: 2448 DPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELH 2507

Query: 99   MSVEESTPIS--RETGE-PYRLSPEPTPLAEPILEVEVTLSKPVPE----------SEFS 145
              V    P +  R  G   +  +P P     P    E +L  PVP+          S F 
Sbjct: 2508 AKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFG 2567

Query: 146  SSPLQAPTPLASHTVEI--HEPNG--MVPSEDLEPEVESSPELAPPPACPSESPVPIAPT 201
              P        ++TV      P+G  + PS     E      L PP   P     P AP 
Sbjct: 2568 PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP-----PPAPD 2622

Query: 202  AQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEM 261
                 L +GA     +  SPV + E+    + +S+A   +P     T     S   + E+
Sbjct: 2623 GSLPYLSHGASQRSGIT-SPVEKREDPGTGMGSSLATAELPG----TQDPGMSGLSQTEL 2677

Query: 262  EEEEEEE 268
            E++ + +
Sbjct: 2678 EKQRQRQ 2684



 Score = 35.8 bits (81), Expect = 0.30
 Identities = 46/215 (21%), Positives = 71/215 (33%), Gaps = 57/215 (26%)

Query: 50   GLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISR 109
            G PGP+  P +   + P P   P     PG+     VL                      
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLG--------------------- 4303

Query: 110  ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 169
                P   +P P+   EP                    P Q P+P +    E   P    
Sbjct: 4304 ----PVHPTPPPSSPQEP------------------KRPSQLPSPSSQLPTEAQLP---- 4337

Query: 170  PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQA 229
            P+    P+ +  P L PPP   S +   +A T   + L    P  P  +L+   +PE+  
Sbjct: 4338 PTHPGTPKPQ-GPTLEPPPGRVSPAAAQLADTLFSKGL---GPWDPPDNLAETQKPEQ-- 4391

Query: 230  KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEE 264
                +S+ P  +        P A+  + ++E  EE
Sbjct: 4392 ----SSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422



 Score = 34.3 bits (77), Expect = 0.86
 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 14/100 (14%)

Query: 151  APTPLASHTVEIHEPNGMVPSEDLEPEVESSPE---LAPPPACPSESP---VPIAPTAQP 204
            AP P   H+   +  N  V      P  E SP    LAP PA P   P   +P  P A+P
Sbjct: 4885 APEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP 4944

Query: 205  EELLNGAPSPPAVDLSPVS---EPEEQAKEVTASMAPPTI 241
                   PSP  +  SP S   +P  +  E      PP +
Sbjct: 4945 P-----VPSPLPLASSPESARPKPRARPPEEGEDSRPPRL 4979



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 93/419 (22%), Positives = 145/419 (34%), Gaps = 72/419 (17%)

Query: 8    STPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPS 67
            S+P   Q   G  P A G   + +++  P  +  G I+       GP   PS+ + S P 
Sbjct: 2725 SSPAFEQLSRGQTPFA-GTQDKSSLVGLPPSKLSGPIL-------GPGSFPSDDRLSRPP 2776

Query: 68   PTPSPSPV------LEPGSEPNLAVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSPE 120
            P  +PS +      L  GS+        PG   +   Q  + +    +  T   + +S  
Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSAR 2836

Query: 121  ----PTP------LAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHE-PNGMV 169
                P P      L  P+  +   L  P         P+  P   A      H    G+ 
Sbjct: 2837 FPSTPGPELGRQALGSPLAGISTRLPGP-------GEPVPGPAGPAQFIELRHNVQKGLG 2889

Query: 170  PSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-----SPPAVDLSPVSE 224
            P     P     P   P     SE P  +AP       ++G P     +PPA +L+    
Sbjct: 2890 PGG--TPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLH 2947

Query: 225  PEEQAKEVTASMAPPTI---PSAT------PATAPSATSPAQEEEMEEE-------EEEE 268
            P    K  T       +   PS+T      P    +   P ++ E++++       E++E
Sbjct: 2948 PTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKALEDDE 3007

Query: 269  E----GEAGEAGEAESEKGGEELLPPESTPIPANLS-QNLEAAAATQVAVSVPKRR---- 319
            E    G   +  + + E G  E L      +   L+    +  A T   +    ++    
Sbjct: 3008 ELAHLGLGVDVAKGDDELGTLENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFN 3067

Query: 320  ---RKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPA--GSNPGPESEGSGVPPRPEE 373
               R ++  N+K     LL    E  P  PE E  PPA   S P   S    V P+ EE
Sbjct: 3068 EHLRLVESANEKAEREALLRGV-EPGPLGPE-ERPPPAADASEPRLASVLPEVKPKVEE 3124


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 95/390 (24%), Positives = 133/390 (34%), Gaps = 63/390 (16%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRP--------GLPG 53
            + A   STP  P +     P     T   A +  P++ +  A     P         +P 
Sbjct: 989  TAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPT 1048

Query: 54   PEHS-------PSESQPSSPS---PTP----SPSPVLEPGSEPNLAVLSIPGDTMTTIQM 99
            PE         P+  +P+SP+   PTP    SP+  +    EP     ++P     T   
Sbjct: 1049 PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPT--- 1105

Query: 100  SVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159
            S   + P   E   P    P P   A P   V      P PE     +P   PTP  S +
Sbjct: 1106 SPAAAVPTPEEPASPAAAVPTPEEPASPAAAV------PTPEEPAFPAP-AVPTPEESAS 1158

Query: 160  VEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPAVD 218
              +  P          PE  +SP  A P PA  +     +A   +P       P+P A+ 
Sbjct: 1159 AAVAVPT---------PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAM- 1208

Query: 219  LSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEA 278
            ++ + E    A  V  S  P ++ +A  +     TSPA    +   EE     A      
Sbjct: 1209 VATLEEFTSPAASVPTSEEPASLAAAV-SNPEEPTSPA--AAVPTLEEPTSSAAAVLTPE 1265

Query: 279  ESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAF 338
            E       +  PE    PA    NLE  A+   AV  P+                 + A 
Sbjct: 1266 ELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE-----------------VAAI 1308

Query: 339  KEANPAVPEVENQPPAGSNPGPESEGSGVP 368
              A+   PEV   P A   P  E    GVP
Sbjct: 1309 PAASVPTPEVPAIPAAAVPPMEEVSPIGVP 1338



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 86/333 (25%), Positives = 110/333 (33%), Gaps = 38/333 (11%)

Query: 58   PSESQPSSPSPTPSPSPVLEPGSEPNLAVL--SIPGDTMTTIQMSVEESTPISRETGEPY 115
            P   +  +P    +P+  +    EP+ A +  S P +  +          P S     P 
Sbjct: 963  PITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPT 1022

Query: 116  RLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQA-PTPLASHTVEIHEPNGMVPSEDL 174
               P     A P  E   + +  VP  E  +SP  A PTP      E   P   VP+   
Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVPT--- 1074

Query: 175  EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGA-----PSPPAVDLSPVSEPEEQA 229
             PE  +SP  A P   P E   P A    PEE  + A     P  PA   + V  PEE A
Sbjct: 1075 -PEEPTSPAAAVPT--PEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPA 1131

Query: 230  KEVTASMAP--PTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKG---- 283
                A   P  P  P+    T   + S A      EE            E+ S       
Sbjct: 1132 SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVAT 1191

Query: 284  -GEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKI----------KELNKKEAVG 332
              E   P  S P PA +   LE    T  A SVP                +  +   AV 
Sbjct: 1192 LEEPTSPAASVPTPAAMVATLE--EFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVP 1249

Query: 333  DLLDAFKEANPAVPEVENQPPAGSNPGPESEGS 365
             L +    A   +   E   PA S P PE   S
Sbjct: 1250 TLEEPTSSAAAVLTPEELSSPAASVPTPEEPAS 1282



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 64/290 (22%), Positives = 103/290 (35%), Gaps = 27/290 (9%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHS--PS 59
            S A    TP  P +     P     T   A +  P++ +  A     P  P    +  P+
Sbjct: 1067 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPT 1126

Query: 60   ESQPSSPS---PTPS----PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETG 112
              +P+SP+   PTP     P+P +    E   A +++P    +    +   +   S    
Sbjct: 1127 PEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFA 1186

Query: 113  EPYRLSPEPTPLAEPI---------LEVEVTLSKPVPESEFSSSPLQA------PTPLAS 157
                   EPT  A  +         LE   + +  VP SE  +S   A      PT  A+
Sbjct: 1187 AVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA 1246

Query: 158  HTVEIHEPNGMVPSEDLEPEVESSPELA-PPPACPSESPVPIAPTAQPEELLNGAPSPPA 216
                + EP     +  L PE  SSP  + P P  P+     ++   +P       P+P  
Sbjct: 1247 AVPTLEEPTSSAAAV-LTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEV 1305

Query: 217  VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEE 266
              +   S P  +   + A+  PP +   +P   P     A  + +   EE
Sbjct: 1306 AAIPAASVPTPEVPAIPAAAVPP-MEEVSPIGVPFLGVSAHTDSVPISEE 1354



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 95/375 (25%), Positives = 124/375 (33%), Gaps = 63/375 (16%)

Query: 30   VAVIVRPDDRSQGAIIADR--PGLPGPEHSPSESQPSSPSPT-------PSPSPVLEPGS 80
            + V+ RP   +    + D     LP PE   S +   +P  T       P P   +   S
Sbjct: 828  IPVLQRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVAS 887

Query: 81   EPNL-------AVLSIPGD-TMTTIQMSVEESTPISRETGEPYRLSP--------EPTPL 124
              +L       A +S P   T+  + +SV E T        P   +P        E    
Sbjct: 888  IVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSA 947

Query: 125  AEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPEL 184
                      L+  VP +E   +P    TP    TV   E           PE  +SP  
Sbjct: 948  VAGFSPEWAALAITVPITEEDGTPEGPVTPAT--TVHAPEEPDTAAVRVSTPEEPASPAA 1005

Query: 185  APPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSA 244
            A P   P E   P A    PEE     P+ PA  + P  EP   A  V  +   PT P+A
Sbjct: 1006 AVP--TPEEPTSPAAAVPTPEE-----PTSPAAAVPPPEEPTSPAAAV-PTPEEPTSPAA 1057

Query: 245  TPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLE 304
               T    TSPA    +   EE     A      E       +  PE    PA      E
Sbjct: 1058 AVPTPEEPTSPA--AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE 1115

Query: 305  AAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANP--AVPEVENQP-PAGSNPGPE 361
              A+   AV  P+                     + A+P  AVP  E    PA + P PE
Sbjct: 1116 EPASPAAAVPTPE---------------------EPASPAAAVPTPEEPAFPAPAVPTPE 1154

Query: 362  SEGSG--VPPRPEEA 374
               S     P PEE+
Sbjct: 1155 ESASAAVAVPTPEES 1169


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 109/487 (22%), Positives = 187/487 (38%), Gaps = 34/487 (6%)

Query: 213 SPPAVDL-SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271
           SPPA +  SP  E +   KE   S A    P    A +P+     ++ +   +EE +   
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPP 562

Query: 272 AGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAV 331
             ++ E E  K   E+  PE    PA      E A +   A S  K +  +KE  K  A 
Sbjct: 563 EAKSPEKEEAKSPAEVKSPEKAKSPAK-----EEAKSPAEAKSPEKAKSPVKEEAKSPA- 616

Query: 332 GDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENI 391
            +     KE   +  EV++   A S    E++       PE+ +     K      AE  
Sbjct: 617 -EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAK 675

Query: 392 QPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQFIFASMQKPEGLPHISDVVLDKANKT 451
            P + K   K++   P   E+ K   +E     +   + +++    P  +   + +  KT
Sbjct: 676 SPEKAKSPVKAEAKSP---EKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKT 732

Query: 452 PLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRGPPRGGPGGELPRGPAGLGPRRSQQG 511
           P +   P + +  +     +P  A     TL  + P    P  E  R PA   P +++  
Sbjct: 733 PEKAKSPVKEEAKSPEKAKSPEKAK----TLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788

Query: 512 PRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSKRTAADKDRGEEDADGSKTQDLFRRV 568
            ++E   P K  A   + ED K  + E   K   K    ++++ +E     K ++  ++ 
Sbjct: 789 VKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQE----VKVKEPPKKA 842

Query: 569 RSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVIDLIFEKAISEPNFSVAYANMCRCLMA 628
                  TP+  ++  K   +     +E  K  ++   E A+ +P  S   A        
Sbjct: 843 EEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDK 900

Query: 629 LKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD-------EVFEKKQKEMDEAATAEE 680
            KVPT EK     V  ++    + + E  K + DD       +  EKK+   ++  T EE
Sbjct: 901 KKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEE 960

Query: 681 RGRLKEE 687
           + +  EE
Sbjct: 961 KAKKPEE 967



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 84/364 (23%), Positives = 140/364 (38%), Gaps = 39/364 (10%)

Query: 54   PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
            PE + S  +  + SP  + SPV      P  A   +  +  +      +  +P+  E   
Sbjct: 649  PEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSP----EKAKSPVKEEAKS 704

Query: 114  PYRL-------SPEPTPLAEPILEVEVTLSKPV-PESEFSSSPLQAPTPLASHTVEIHEP 165
            P +        +  P     P+ E   T  K   P  E + SP +A +P  + T+++  P
Sbjct: 705  PEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSP 764

Query: 166  NGMVPS-EDLEPEVESSPELAPPPA-----CPSESPVPIAPTAQ-PEELL---NGAPSPP 215
                P+ E+     +  PE A  P       P ++  P+   A+ PE+ +       SP 
Sbjct: 765  EAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPV 824

Query: 216  AVDLSP----VSEPEEQAKEVTASMAPPTIPSATP----ATAPSATSPAQEEEMEEEEEE 267
              +  P    V EP ++A+E  A   P T          A    A  P  EE+ E   E+
Sbjct: 825  KEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884

Query: 268  EEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVP---KRRRKIKE 324
             +    EA + E+E   +   P +  P    + ++ +    T+VA   P   K +   K 
Sbjct: 885  PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944

Query: 325  LNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSGVPPRPE----EADETWDS 380
              KKEA  +  D  KE     PE + +  A +    ++  S  P +P+    E   + D 
Sbjct: 945  AEKKEAAPEKKDT-KEEKAKKPEEKPKTEAKAKEDDKTL-SKEPSKPKAEKAEKSSSTDQ 1002

Query: 381  KEDK 384
            K+ K
Sbjct: 1003 KDSK 1006



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 99/425 (23%), Positives = 160/425 (37%), Gaps = 45/425 (10%)

Query: 17  GGLEPQANG-----ETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPS 71
           GG E +A G     ++P       P+  ++  +  +    P    SP + +  SP+   S
Sbjct: 488 GGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSPAEVKS 546

Query: 72  P----SPVLEPGSEPNLAVLSIPGDTMTTIQMSVEE--STPISRETGEPYRL-SPE--PT 122
           P    SP  E    P  A      +  +  ++   E   +P   E   P    SPE   +
Sbjct: 547 PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKS 606

Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
           P+ E   E +       P  E + SP +  +P  + +    E      ++  E E   SP
Sbjct: 607 PVKE---EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP 663

Query: 183 ELAPPPA-----CPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP-EEQAKEVTASM 236
           E A  P       P ++  P+   A+  E         A        P +E+AK    + 
Sbjct: 664 EKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAK 723

Query: 237 APPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAG----EAGEAESEKGGEELLPPES 292
           +P    + TP     A SP +EE    E+ +   +A     ++ EA++    E   P + 
Sbjct: 724 SPVKEEAKTP---EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 293 TPIPANLSQNLEAAAATQVAVSVPKRRRKI--KELNKKEAVGDLLDAFKEANPAVPEVEN 350
            P  A  S   E   + + A S  K   K   KE+ KKE V          +P   E + 
Sbjct: 781 FPEKAK-SPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEV---------KSPVKEEEKP 830

Query: 351 QPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPG-EQKYEYKSDQWKPLN 409
           Q      P  ++E    P  P + +E  DSK+++    E  +P  E+K E   ++ K   
Sbjct: 831 QEVKVKEPPKKAEEEKAPATP-KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889

Query: 410 LEEKK 414
           +E KK
Sbjct: 890 VEAKK 894



 Score = 54.3 bits (129), Expect = 8e-07
 Identities = 85/367 (23%), Positives = 134/367 (36%), Gaps = 28/367 (7%)

Query: 61  SQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPE 120
           S P      PS S  ++  SE  + V+         ++   EE+      T E  + + E
Sbjct: 421 SLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480

Query: 121 PTPLAEPILEVEVTL-----SKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLE 175
                E   E E        +K  P  E +S   +A +P+        E       E   
Sbjct: 481 EEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS 540

Query: 176 PEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAP-SPPAVDLSPVSEPEE---QAKE 231
           P    SPE A  PA       P A + + EE  + A    P    SP  E  +   +AK 
Sbjct: 541 PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKS 600

Query: 232 VTASMAPPTIPSATPATAPS-----ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEE 286
              + +P    + +PA A S     A SPA+ +  E+ +   + EA    +A+S +  EE
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KEE 659

Query: 287 LLPPESTPIPANLSQNLEAAAATQV---AVSVPKRRRKIKELNK-----KEAVGDLLDAF 338
              PE    P          A + V   A S  K +  +KE  K     K  V +   + 
Sbjct: 660 AKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSP 719

Query: 339 KEANPAVPEVENQPPAGSNPGPESEGSGVPPRPEEADETWDSKEDKIHNAENIQPGEQKY 398
           ++A   V E    P    +P  E   S     PE+A     +K   + + E   P +++ 
Sbjct: 720 EKAKSPVKEEAKTPEKAKSPVKEEAKS-----PEKAKSPEKAKTLDVKSPEAKTPAKEEA 774

Query: 399 EYKSDQW 405
              +D++
Sbjct: 775 RSPADKF 781



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 132/625 (21%), Positives = 214/625 (34%), Gaps = 90/625 (14%)

Query: 72  PSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEV 131
           P P   P   P +  +S      T I++  EE   +  ++ +   +  E T   +   EV
Sbjct: 417 PIPFSLPEGLPKIPSVS------THIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEV 470

Query: 132 EVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDL-EPEVESSPELAPPPAC 190
                K   E E                 E   P    P+E+   PE E+   +      
Sbjct: 471 TEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP----PAEEAASPEKEAKSPVKEEAKS 526

Query: 191 PSESPVPIAPTAQ-PEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATA 249
           P+E+  P    A+ P E+ +   +         S PE ++ E   + +P  + S   A +
Sbjct: 527 PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKS 586

Query: 250 PS---ATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPIPANLSQNLEAA 306
           P+   A SPA+ +  E+ +   + EA    EA+S    E   P E        S   E A
Sbjct: 587 PAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEA 646

Query: 307 AATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQPPAGSNPGPESEGSG 366
            + + A S  K   K  E  K            +A    PE    P       PE   S 
Sbjct: 647 KSPEKAKSPEKEEAKSPEKAKSPV---------KAEAKSPEKAKSPVKAEAKSPEKAKS- 696

Query: 367 VPPRPEEADETWDSKEDKIHNAENIQPGEQKYEYKSDQWKPLNLEEKKRYDREFLLGFQF 426
             P  EEA     +K      A++  P + K   K +   P    EK +           
Sbjct: 697 --PVKEEAKSPEKAKSPVKEEAKS--PEKAKSPVKEEAKTP----EKAK----------- 737

Query: 427 IFASMQKPEGLPHISDVVLDKANKTPLRPLDPTRLQGINCGPDFTPSFANLGRTTLSTRG 486
              S  K E              K+P +   P + +                  TL  + 
Sbjct: 738 ---SPVKEEA-------------KSPEKAKSPEKAK------------------TLDVKS 763

Query: 487 PPRGGPGGELPRGPAGLGPRRSQQGPRKE---PRKIIATVLMTEDIKLNKAEKAWKPSSK 543
           P    P  E  R PA   P +++   ++E   P K  A   + ED K  + E   K   K
Sbjct: 764 PEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK--AKSPLKEDAKAPEKEIPKKEEVK 821

Query: 544 RTAADKDRGEEDADGSKTQDLFRRVRSILNKLTPQMFQQLMKQVTQLAIDTEERLKGVID 603
               ++++ +E     K ++  ++        TP+  ++  K   +     +E  K  ++
Sbjct: 822 SPVKEEEKPQE----VKVKEPPKKAEEEKAPATPKTEEK--KDSKKEEAPKKEAPKPKVE 875

Query: 604 LIFEKAISEPNFSVAYANMCRCLMALKVPTTEKPT-VTVNFRKLLLNRCQKEFEKDKDDD 662
              E A+ +P  S   A         KVPT EK     V  ++    + + E  K + DD
Sbjct: 876 EKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDD 935

Query: 663 EVFEKKQKEMDEAATAEERGRLKEE 687
              ++  K  ++   A E+   KEE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEE 960



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 39/208 (18%), Positives = 68/208 (32%), Gaps = 28/208 (13%)

Query: 21   PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGS 80
            P    E PQ   +  P  +++       P     + S  E  P   +P P      EP  
Sbjct: 823  PVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP-- 880

Query: 81   EPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVP 140
                            ++   E      +E  E  +  P P   A   +EV+   +KP  
Sbjct: 881  ---------------AVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKED-AKPKE 924

Query: 141  ESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAP 200
            ++E +               +  EP+     ++  PE + + E       P E P   A 
Sbjct: 925  KTEVAKK--------EPDDAKAKEPSKPAEKKEAAPEKKDTKE--EKAKKPEEKPKTEAK 974

Query: 201  TAQPEELLNGAPSPPAVDLSPVSEPEEQ 228
              + ++ L+  PS P  + +  S   +Q
Sbjct: 975  AKEDDKTLSKEPSKPKAEKAEKSSSTDQ 1002


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 92/360 (25%), Positives = 129/360 (35%), Gaps = 29/360 (8%)

Query: 54   PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
            P   P  S    PS  P PS    P +  N   LS+PG      ++        +    +
Sbjct: 678  PSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNED 737

Query: 114  PYRLSPEPTPLAEPILEVEVTLSKPVPESEF------SSSPLQAPTPLASHTVEIHEPNG 167
            P  L+P  TP   P +  + T    VP   F       +S ++      S    +  P G
Sbjct: 738  PI-LAPSGTP--PPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEG 794

Query: 168  MVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEEL------LNGAPSPPAVDLSP 221
            + P     P   + P +AP    P+ SP P+    +PEEL      L   P PP     P
Sbjct: 795  LPPLPPPPPSGATPPPIAPTGP-PTASP-PVPAKEEPEELPAAPGPLPPPPPPPPPVPGP 852

Query: 222  VSEPEEQA--KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAE 279
            V+ P  Q   +       PP +         +++   +EEE EEEEEEEE E  E    E
Sbjct: 853  VTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEE 912

Query: 280  SEKGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFK 339
             E+  EE    E         +  E            +   + +EL + E + +   A  
Sbjct: 913  EEEDEEEYFEEEEEE-EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL-EFGTAGG 970

Query: 340  EANPAVPEVENQPPAGSNPGPESEGSGVP-PRPE-----EADETWDSKEDKIHNAENIQP 393
            E     P     PPA   P PES     P P PE     E +E    +E     A  + P
Sbjct: 971  EVEEGAPPPPTLPPA--LPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 84/312 (26%), Positives = 108/312 (34%), Gaps = 28/312 (8%)

Query: 10   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69
            P PP +G    P A    P  +  V   +  +     + P  PGP   P    P  P P 
Sbjct: 799  PPPPPSGATPPPIAPTGPPTASPPVPAKEEPE-----ELPAAPGPLPPPPPPPPPVPGPV 853

Query: 70   PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSV---EESTPISRETGEPYRLSPEPTPLAE 126
              P P L P   P         + +T I ++    EE      E  E      E     E
Sbjct: 854  TLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEE 913

Query: 127  PILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEI--HEPNGMVPSEDLE-----PEVE 179
               E E    +   E EF     +    L     E    E   +   EDLE      EVE
Sbjct: 914  EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973

Query: 180  SSPELAPPPACPSESPVPIAPT-AQPEELLNGAPSPPAVDLSPVSEP---EEQAKEVTAS 235
                  PPP  P   P P +P   QPE      P P    L  V EP   EE+  +   +
Sbjct: 974  EGAP--PPPTLPPALPPPESPPKVQPE------PEPEPGLLLEVEEPGTEEERGADTAPT 1025

Query: 236  MAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESEKGGEELLPPESTPI 295
            +AP  +PS          SPA     +E  EEE        E E+E G +++ PP  TP 
Sbjct: 1026 LAPEALPSQGEVER-EGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQPPPETPA 1084

Query: 296  PANLSQNLEAAA 307
               +    EA A
Sbjct: 1085 EEEMETETEAEA 1096



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 75/321 (23%), Positives = 116/321 (36%), Gaps = 41/321 (12%)

Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
           P   P+  +  T   P P       P +AP+P  +     H P  M       P V S P
Sbjct: 633 PRVPPLQPMGPTCPTPAPVP-----PPEAPSPFRAPP--FHPPGPM-------PSVGSMP 678

Query: 183 ELAPPPAC---PSESPVPIAPTAQPEELLN-GAPSPPAVDLSPVSEPEEQAKEVTASMAP 238
              P P+    PS  PVP A    P    + G   P  V + P   P  +     ++  P
Sbjct: 679 SAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDP 738

Query: 239 PTIPSATPATA--PSATSPAQ--EEEMEEEEEEEEGEAGEAGEAESEKGG---EELLPPE 291
              PS TP     P  T   +         ++EE  +   + E++S+       E LPP 
Sbjct: 739 ILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPL 798

Query: 292 STPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKEAVGDLLDAFKEANPAVPEVENQ 351
             P P+  +    A      A      + + +EL    A    L       P VP     
Sbjct: 799 PPPPPSGATPPPIAPTGPPTASPPVPAKEEPEEL---PAAPGPLPPPPPPPPPVPGPVTL 855

Query: 352 PPAGSNPGPESEGSGVPPRPEE---------ADETWDSKEDKIHNAENIQPGEQKYEYK- 401
           PP    P   + G G PP  EE         +DE  + +E++    E  +  E+ +E + 
Sbjct: 856 PPPQLVP-EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914

Query: 402 --SDQWKPLNLEEKKRYDREF 420
              +++     EE++ ++ EF
Sbjct: 915 EDEEEYFEEEEEEEEEFEEEF 935



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 15/42 (35%), Positives = 29/42 (69%), Gaps = 3/42 (7%)

Query: 652 QKEFEKDKDDDEVF---EKKQKEMDEAATAEERGRLKEELEE 690
           +++FE++++D+E +   E++++E  E    EE G L+EE EE
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 73/250 (29%), Positives = 90/250 (36%), Gaps = 44/250 (17%)

Query: 3   GARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQ 62
           GA  A    PPQ G     +   E+P+      P            P  P P  +P    
Sbjct: 4   GAAAAQGTAPPQDG-----EQPAESPEPPPPWPPP-----------PPPPAPPPAPPLLS 47

Query: 63  PSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPT 122
            +SP P P P P L PG  P     S    T    + + E +T  + E        P P 
Sbjct: 48  EASPEPIPEPCPELAPGPCPEATSESA---TELYTEPTPEPATEPASEPAPEPATEPAPE 104

Query: 123 PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
           P  EP  E       P PE    S+P   P P      E        P+ +L PEV  +P
Sbjct: 105 PATEPAPE-------PAPEPATESAPEPTPEPALESVPE--------PAPELTPEV--AP 147

Query: 183 ELAPPPACPSESPVPIAPTAQPEELLNGAPSP-PAVDLSPVSEPEEQAKEVTASMAPPTI 241
           ELAP P    E    +AP   PE      PSP P +   PV   E   K      +P   
Sbjct: 148 ELAPEPT--PEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLK-----TSPSPS 200

Query: 242 PSATPATAPS 251
           PS +P T  S
Sbjct: 201 PSPSPRTPMS 210



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 48/159 (30%), Positives = 55/159 (34%), Gaps = 19/159 (11%)

Query: 110 ETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMV 169
           + GE    SPEP P   P          P   SE S  P+  P P  +         G  
Sbjct: 15  QDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAP--------GPC 66

Query: 170 PSEDLEPEVESSPELAPPPAC-PSESPVPIAPTAQ-PEELLNGAPSP---PAVDLSPVSE 224
           P    E   E   E  P PA  P+  P P   T   PE     AP P   PA + +P   
Sbjct: 67  PEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPT 126

Query: 225 PEEQAKEVTASMAPPTIPSATPATAPS-ATSPAQEEEME 262
           PE   + V     P   P  TP  AP  A  P  E   E
Sbjct: 127 PEPALESV-----PEPAPELTPEVAPELAPEPTPEPVTE 160



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 44/141 (31%), Positives = 52/141 (36%), Gaps = 20/141 (14%)

Query: 167 GMVPSEDLEPEVESS----------PELAPPPACPSESPVPIAPTAQPEELLNGAPSPPA 216
           G  P +D E   ES           P  APPPA P  S     P  +P   L   P P A
Sbjct: 10  GTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69

Query: 217 VDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAG 276
              S      E   E      P T P++ PA  P AT PA E   E   E     A E+ 
Sbjct: 70  TSESATELYTEPTPE------PATEPASEPAPEP-ATEPAPEPATEPAPEPAPEPATESA 122

Query: 277 EAESEKGGEELLP---PESTP 294
              + +   E +P   PE TP
Sbjct: 123 PEPTPEPALESVPEPAPELTP 143


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%)

Query: 3   GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 58
           G  TA        G  L P+      G  P+   +      SQ +I A   G    +  P
Sbjct: 574 GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 633

Query: 59  SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 114
           +  QPS   P+P     L  G+E P     S+PG           + +P S   G P   
Sbjct: 634 AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 692

Query: 115 -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 166
                Y   P  TP   P  +    +LS+P P    +    + P  + L S+      P 
Sbjct: 693 PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 752

Query: 167 GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 215
                      V +SP + P PA  +      A       P   P + L+     +P PP
Sbjct: 753 RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 805

Query: 216 AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271
            +D SP   P+E A    +   +  A P+ P   PA A  A+   +EE   E      G 
Sbjct: 806 PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 863

Query: 272 AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 323
           +GE G   +E+G   +         PP  TP+P  L  NL  +          KRR K +
Sbjct: 864 SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 915

Query: 324 ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 368
           E   +E +   L AF  A+    PA     P     PPA S P PE       GVP
Sbjct: 916 E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 968



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%)

Query: 4    ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 54
            AR    P PP       +G   EP    E+P   + A   R    S+ A  ++ PG P P
Sbjct: 781  ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 840

Query: 55   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114
                S+++   P P  +P     P    +   L    +   TI+   + + P  RET  P
Sbjct: 841  AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 895

Query: 115  ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159
                + L+   T           PL   +L   V  + P P     ++PL +PTP  S  
Sbjct: 896  PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 948

Query: 160  VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219
                            P   S P+  P        P P+AP+   +  +   P  P ++ 
Sbjct: 949  ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 991

Query: 220  SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256
            S  S    + +   A  A   +P A   TAP   S A
Sbjct: 992  SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1026



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 54
            +G     TP PP     L      +T +     R  +  Q A++A         P  P P
Sbjct: 885  AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 941

Query: 55   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114
              +P ES P+S  P P PS +   G    LA        +        ES+  SR  GE 
Sbjct: 942  SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1000

Query: 115  YRLSPEPTPLAEPILEVEVTLSKPVPES 142
                 EP      +L+V    + P P S
Sbjct: 1001 ----TEPPAAPAALLKVPGAGTAPKPVS 1024


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 109/416 (26%), Positives = 150/416 (36%), Gaps = 71/416 (17%)

Query: 3    GARTASTPTPPQTGGGLEPQAN----GETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSP 58
            G  TA        G  L P+      G  P+   +      SQ +I A   G    +  P
Sbjct: 656  GPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQP 715

Query: 59   SESQPSSPSPTPSPSPVLEPGSE-PNLAVLSIPGDTMTTIQMSVEESTPISRETGEP--- 114
            +  QPS   P+P     L  G+E P     S+PG           + +P S   G P   
Sbjct: 716  AP-QPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGA 774

Query: 115  -----YRLSPEPTPLAEPILEVEV-TLSKPVPESEFSSSPLQAP--TPLASHTVEIHEPN 166
                 Y   P  TP   P  +    +LS+P P    +    + P  + L S+      P 
Sbjct: 775  PWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPG 834

Query: 167  GMVPSEDLEPEVESSPELAPPPACPSESPVPIA-------PTAQPEELLNG----APSPP 215
                       V +SP + P PA  +      A       P   P + L+     +P PP
Sbjct: 835  RSAL-------VRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP 887

Query: 216  AVDLSPVSEPEEQA----KEVTASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGE 271
             +D SP   P+E A    +   +  A P+ P   PA A  A+   +EE   E      G 
Sbjct: 888  PLDESP--GPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGS 945

Query: 272  AGEAGEAESEKGGEELL--------PPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIK 323
            +GE G   +E+G   +         PP  TP+P  L  NL  +          KRR K +
Sbjct: 946  SGE-GLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTES-------DTVKRRPKCR 997

Query: 324  ELNKKEAVGDLLDAFKEAN----PAV----PEVENQPPAGSNPGPESE---GSGVP 368
            E   +E +   L AF  A+    PA     P     PPA S P PE       GVP
Sbjct: 998  E---REPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVP 1050



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 66/277 (23%), Positives = 98/277 (35%), Gaps = 55/277 (19%)

Query: 4    ARTASTPTPPQ------TGGGLEPQANGETP---QVAVIVRPDDRSQGAIIADRPGLPGP 54
            AR    P PP       +G   EP    E+P   + A   R    S+ A  ++ PG P P
Sbjct: 863  ARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAP 922

Query: 55   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114
                S+++   P P  +P     P    +   L    +   TI+   + + P  RET  P
Sbjct: 923  AGPASDTEEEEPGPEGTP-----PSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP 977

Query: 115  ----YRLSPEPT-----------PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHT 159
                + L+   T           PL   +L   V  + P P     ++PL +PTP  S  
Sbjct: 978  PGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP-----AAPLPSPTPGES-- 1030

Query: 160  VEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDL 219
                            P   S P+  P        P P+AP+   +  +   P  P ++ 
Sbjct: 1031 ----------------PPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPG-PGLES 1073

Query: 220  SPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256
            S  S    + +   A  A   +P A   TAP   S A
Sbjct: 1074 SAASRWNGETEPPAAPAALLKVPGA--GTAPKPVSVA 1108



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 39/148 (26%), Positives = 53/148 (35%), Gaps = 15/148 (10%)

Query: 2    SGARTASTPTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIA-------DRPGLPGP 54
            +G     TP PP     L      +T +     R  +  Q A++A         P  P P
Sbjct: 967  AGPPPRETPVPPGLDFNL---TESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLP 1023

Query: 55   EHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEP 114
              +P ES P+S  P P PS +   G    LA        +        ES+  SR  GE 
Sbjct: 1024 SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGE- 1082

Query: 115  YRLSPEPTPLAEPILEVEVTLSKPVPES 142
                 EP      +L+V    + P P S
Sbjct: 1083 ----TEPPAAPAALLKVPGAGTAPKPVS 1106


>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
           P ++P+ +  S P+ TPS +P L P S+P L   S P  T ++       +TP    +  
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 114 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173
           P  L+P  TP   P     +T   P P    SS+P    TP +  T+       + PS  
Sbjct: 64  P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117

Query: 174 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 227
                 ++P L P   P   PS +P  + P+++P  +L  + +P    L+P S P     
Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171

Query: 228 QAKEVTASMAPPTIPSATPATAPSAT 253
               +T S  P   PS+TP   PS+T
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%)

Query: 11  TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 70
           TP  T           TP +     P    Q  +         P   P+ +  ++P+ TP
Sbjct: 55  TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114

Query: 71  SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 130
           S +P L P + P L   S P  T ++       S PI   +      +P  TP + PIL 
Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169

Query: 131 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 187
              T +   P S  + +P   PT   S T        + PS        S+P L P   P
Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222

Query: 188 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 247
              PS +P  + P+++P  +L  + +P     S  +        +T S  P   PS TP 
Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 248 TAPSAT 253
             PS+T
Sbjct: 280 LTPSST 285



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
           P   P  ++ S+P+ TPS +P L P + P L     P +T T    +    TP S  T  
Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287

Query: 114 PYRLSPEPTPLAEP 127
              L+P  TP   P
Sbjct: 288 ---LTPSSTPTLTP 298



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 97
           P ++P+ +  ++P+ TPS +P L P S P L   S P  T +++
Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 140 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 199
           P +  + +P   PT   S T  +   +  + +    P +  S   +PP   PS +P  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59

Query: 200 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255
           P+  P    +  P+     L+P S P    + +    + PT+  ++P T   + +P
Sbjct: 60  PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110


>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 306

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 18/206 (8%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
           P ++P+ +  S P+ TPS +P L P S+P L   S P  T ++       +TP    +  
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63

Query: 114 PYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSED 173
           P  L+P  TP   P     +T   P P    SS+P    TP +  T+       + PS  
Sbjct: 64  P-TLTPSSTPTLTPSSTPTLT---PQPILTRSSTP--TLTPSSPPTLTPSNTPTLTPSNT 117

Query: 174 LEPEVESSPELAP---PPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEP---EE 227
                 ++P L P   P   PS +P  + P+++P  +L  + +P    L+P S P     
Sbjct: 118 PTLTPSNTPTLTPSSTPTLTPSSTPT-LTPSSRP--ILTRSSTP---TLTPSSRPILTRS 171

Query: 228 QAKEVTASMAPPTIPSATPATAPSAT 253
               +T S  P   PS+TP   PS+T
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSST 197



 Score = 60.8 bits (146), Expect = 9e-09
 Identities = 63/246 (25%), Positives = 93/246 (37%), Gaps = 18/246 (7%)

Query: 11  TPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTP 70
           TP  T           TP +     P    Q  +         P   P+ +  ++P+ TP
Sbjct: 55  TPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 114

Query: 71  SPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPILE 130
           S +P L P + P L   S P  T ++       S PI   +      +P  TP + PIL 
Sbjct: 115 SNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSS-----TPTLTPSSRPILT 169

Query: 131 VEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---P 187
              T +   P S  + +P   PT   S T        + PS        S+P L P   P
Sbjct: 170 RSSTPTL-TPSSTPTLTPSSTPTLTPSSTPT------LTPSSRPILTRSSTPTLTPSSRP 222

Query: 188 PACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPA 247
              PS +P  + P+++P  +L  + +P     S  +        +T S  P   PS TP 
Sbjct: 223 ILTPSSTPT-LTPSSRP--ILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPT 279

Query: 248 TAPSAT 253
             PS+T
Sbjct: 280 LTPSST 285



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 9/74 (12%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
           P   P  ++ S+P+ TPS +P L P + P L     P +T T    +    TP S  T  
Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLT----PSNTPTLTPSNTPTLTPSSTPT-- 287

Query: 114 PYRLSPEPTPLAEP 127
              L+P  TP   P
Sbjct: 288 ---LTPSSTPTLTP 298



 Score = 32.7 bits (73), Expect = 2.5
 Identities = 15/44 (34%), Positives = 26/44 (59%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTI 97
           P ++P+ +  ++P+ TPS +P L P S P L   S P  T +++
Sbjct: 258 PSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSL 301



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 9/116 (7%)

Query: 140 PESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPPACPSESPVPIA 199
           P +  + +P   PT   S T  +   +  + +    P +  S   +PP   PS +P  + 
Sbjct: 4   PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPS---SPPTLTPSNTPT-LT 59

Query: 200 PTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSP 255
           P+  P    +  P+     L+P S P    + +    + PT+  ++P T   + +P
Sbjct: 60  PSNTPTLTPSSTPT-----LTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTP 110


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 62/230 (26%), Positives = 93/230 (40%), Gaps = 20/230 (8%)

Query: 36  PDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMT 95
           P +     +    P    P ++P+ +  S+P+ TP  +P L P + P L   S P  T +
Sbjct: 46  PREMGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPS 105

Query: 96  TIQMSVEESTPISRETGEPYRLSPEPTPLAEPILEVEVTLSKPVPESEFSSSPLQAP--- 152
           +       STP    +  P  L+P  TP   P     +T S   P    SS+P   P   
Sbjct: 106 STPTLTPSSTPTLTPSSTP-TLTPSSTPTLTPSSTPTLTRSS-TPTLTPSSTPTLTPSST 163

Query: 153 ---TPLASHTVEIHEPNGMVPSEDLEPEVESSPELAP---PPACPSESPVPIAPTAQPEE 206
              TP ++ T+       + PS        S+P L P   P   PS +P  + P+  P  
Sbjct: 164 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPT-LTPSNTPTL 222

Query: 207 LLNGAPSPPAVDLSPVSEP---EEQAKEVTASMAPPTIPSATPATAPSAT 253
           + +  P+     L+P S P         +T S  P   PS+TP   PS+T
Sbjct: 223 IPSSTPT-----LTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSST 267



 Score = 36.2 bits (82), Expect = 0.23
 Identities = 19/53 (35%), Positives = 27/53 (50%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTP 106
           P ++P+    S+P+ TPS +P L P S P L   S P  T ++       STP
Sbjct: 216 PSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSSTP 268



 Score = 35.0 bits (79), Expect = 0.51
 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 9/74 (12%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGE 113
           P  +P+ +  ++P+  PS +P L P S P L   S P  T ++       STP       
Sbjct: 208 PSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTP------- 260

Query: 114 PYRLSPEPTPLAEP 127
              L+P  TP   P
Sbjct: 261 --TLTPSSTPTLTP 272



 Score = 31.6 bits (70), Expect = 5.6
 Identities = 14/36 (38%), Positives = 21/36 (58%)

Query: 54  PEHSPSESQPSSPSPTPSPSPVLEPGSEPNLAVLSI 89
           P   P+ ++ S+P+ TPS +P L P S P L   S+
Sbjct: 240 PSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSL 275


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 71/312 (22%), Positives = 106/312 (33%), Gaps = 52/312 (16%)

Query: 10   PTPPQTGGGLEPQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSSPSPT 69
            P PP  G    P      P++A+ VRP   +  +I A  P    P  +P+ + P    P 
Sbjct: 853  PAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPV 912

Query: 70   PSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEPTPLAEPIL 129
            P P P+  P + P  A   IP     +  +      P         R+ P+P P  +   
Sbjct: 913  PPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAP---------RIGPQPQPHPQ--- 960

Query: 130  EVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSPELAPPP- 188
                    P P   F   P Q P PL    +   +  G++P +   P       L  PP 
Sbjct: 961  --------PHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPP 1012

Query: 189  -------ACPSESPVPI----------APTAQPEELLNGAPSPPAVDLSPVSEPEEQAKE 231
                     P++ P+P            P   P   L   P+P    + P + P      
Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGP 1072

Query: 232  VTASMAPPT---IPSATPATAPSATSPAQEEEMEEEEEEEEGEA----------GEAGEA 278
             +A  + P+   +PS  P+  P    P +    E       G A           + G  
Sbjct: 1073 SSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGT 1131

Query: 279  ESEKGGEELLPP 290
            +S  GG+ LL P
Sbjct: 1132 QSPGGGQPLLQP 1143



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 68/282 (24%), Positives = 94/282 (33%), Gaps = 50/282 (17%)

Query: 21   PQANGETPQVAVIVRPDDRSQGAIIADRPGLPGPEHSPSESQPSS-PSPTPSPSPVLEPG 79
            P + G  P       P     G     +P  PGP   P    P+  P+P  +P   L P 
Sbjct: 777  PSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPR 836

Query: 80   SEPNLAVLSI-------------------PGDTMTTIQMSVEEST--------PISRETG 112
            S P   V+S                    P  +   + M+V  +T        PI   T 
Sbjct: 837  SSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTA 896

Query: 113  EPYRLSPEPTPLAEPI-----LEVEVT----LSKPVPESEFSSSPLQA--PTPLASHTVE 161
                 +P P P   P+     L    T      +P+P     SS + A  P P      +
Sbjct: 897  PRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQ 956

Query: 162  IH-EPN---GMVPSEDLEPEVESSPELAPPPA---CPSESPVPIAPTAQPEELLNGAPSP 214
             H +P+      P    +P     P L PP A    P +SP P AP  QP  L  G P P
Sbjct: 957  PHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAP--QPGVL--GQPPP 1012

Query: 215  PAVDLSPVSEPEEQAKEVTASMAPPTIPSATPATAPSATSPA 256
            P          ++     + ++  P+     P   P A  PA
Sbjct: 1013 PLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPA 1054



 Score = 32.3 bits (72), Expect = 3.3
 Identities = 31/127 (24%), Positives = 50/127 (39%), Gaps = 15/127 (11%)

Query: 123  PLAEPILEVEVTLSKPVPESEFSSSPLQAPTPLASHTVEIHEPNGMVPSEDLEPEVESSP 182
            P  +P+    ++    +P+       L    P++S    I + + + P   LE  V S P
Sbjct: 1464 PPCKPLASASISQKNHLPQDS-QDLVLGGDVPISSIQATIAKLS-IRPPGGLESPVASLP 1521

Query: 183  ELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSEPEEQAKEVTASMAPPTIP 242
              A PP  P        P + PE     + SPP     P+S P  +A +       P  P
Sbjct: 1522 GPAEPPGLP--------PASLPESTPIPSSSPP-----PLSSPLPEAPQPKEEPPVPEAP 1568

Query: 243  SATPATA 249
            S+ P ++
Sbjct: 1569 SSGPPSS 1575


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.371 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,805,254
Number of Sequences: 37866
Number of extensions: 3811416
Number of successful extensions: 49199
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 468
Number of HSP's successfully gapped in prelim test: 1910
Number of HSP's that attempted gapping in prelim test: 26012
Number of HSP's gapped (non-prelim): 15885
length of query: 1403
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1288
effective length of database: 13,892,928
effective search space: 17894091264
effective search space used: 17894091264
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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