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Search of human proteins with 38045948
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa... 2046 0.0
gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens] 862 0.0
gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens] 862 0.0
gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens] 583 e-166
gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens] 131 4e-30
gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo s... 111 4e-24
gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo s... 111 4e-24
gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 111 4e-24
gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo sap... 111 4e-24
gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens] 106 1e-22
gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens] 106 1e-22
gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo ... 73 1e-12
gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens] 71 4e-12
gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo... 60 1e-08
gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens] 50 8e-06
gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens] 50 8e-06
gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens] 37 0.12
gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens] 37 0.12
gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens] 37 0.12
gi|56711322 ring finger protein 43 [Homo sapiens] 33 1.8
gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo... 32 2.3
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 32 3.0
gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens] 31 5.2
gi|195963410 MEF2 activating motif and SAP domain containing tra... 31 6.7
gi|32698970 MEF2 activating motif and SAP domain containing tran... 31 6.7
gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapi... 31 6.7
gi|116174754 phospholipase A2, group IVD [Homo sapiens] 30 8.8
gi|239755087 PREDICTED: similar to zinc finger protein 598 [Homo... 30 8.8
gi|239749606 PREDICTED: similar to zinc finger protein 598 [Homo... 30 8.8
gi|239743874 PREDICTED: similar to zinc finger protein 598 [Homo... 30 8.8
>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
sapiens]
Length = 1012
Score = 2046 bits (5302), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT 60
MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT
Sbjct: 1 MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLT 60
Query: 61 LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ 120
LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ
Sbjct: 61 LHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQ 120
Query: 121 VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA 180
VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA
Sbjct: 121 VVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAA 180
Query: 181 IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD 240
IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD
Sbjct: 181 IQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGD 240
Query: 241 TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF 300
TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF
Sbjct: 241 TTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKF 300
Query: 301 QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM 360
QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM
Sbjct: 301 QHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPM 360
Query: 361 VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA 420
VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA
Sbjct: 361 VAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIA 420
Query: 421 VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ 480
VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ
Sbjct: 421 VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ 480
Query: 481 FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD 540
FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD
Sbjct: 481 FLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALD 540
Query: 541 SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT 600
SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT
Sbjct: 541 SFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCT 600
Query: 601 VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR 660
VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR
Sbjct: 601 VRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLR 660
Query: 661 VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN 720
VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN
Sbjct: 661 VRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTN 720
Query: 721 QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA 780
QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA
Sbjct: 721 QDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLELASASA 780
Query: 781 EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA 840
EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA
Sbjct: 781 EFGPEQQKELNKALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRA 840
Query: 841 QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA 900
QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA
Sbjct: 841 QSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFA 900
Query: 901 PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP 960
PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP
Sbjct: 901 PAIQTFHHLKWTSWDRLKVPAGQPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSP 960
Query: 961 EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 1012
EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL
Sbjct: 961 EKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTAFPPLHYEL 1012
>gi|23510338 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 862 bits (2228), Expect = 0.0
Identities = 474/1018 (46%), Positives = 644/1018 (63%), Gaps = 25/1018 (2%)
Query: 10 LDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCW 69
+DE LYSRQLYVLG AM+R+Q + VLVSGL+GLG E+AKN++L GV ++TLHD W
Sbjct: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
Query: 70 SDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKL 129
+DL++QF L E+D+ ++RAE SQ LA+LN V V +TG + ED L FQVVVLT L
Sbjct: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPL 169
Query: 130 EEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSP 189
E+QL+VG CH G+ + ADTRGL GQLFCDFGE+ + D +PL+A + +++ +P
Sbjct: 170 EDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNP 229
Query: 190 GILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLR 249
G++T A H F GD V+FS ++GMVELN P I V + I DT+ FS Y+R
Sbjct: 230 GVVTCLDEAR-HGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIR 288
Query: 250 GGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQ 309
GG +++VK PK + KSL +L +P V + LH F ALH+F HGRPP+
Sbjct: 289 GGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPR 348
Query: 310 PWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAA 369
P + DA +V LA+ + R + LDE L+R +A +AG L+P+ A +G +AA
Sbjct: 349 PRNEEDAAELVALAQAVN--ARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAA 406
Query: 370 QEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEK 429
QEV+KA S KFMP+ QWLYFDAL+CLPED E+L + + C R +RYDGQ+AVFG+ QEK
Sbjct: 407 QEVMKACSGKFMPIMQWLYFDALECLPEDKEVL-TEDKCLQRQNRYDGQVAVFGSDLQEK 465
Query: 430 LRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVG 489
L +Q Y LVGAGAIGCELLK FA++GLG G G + V DMD IE+SNL+RQFLFR DV
Sbjct: 466 LGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVT 525
Query: 490 RPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVA 549
+ K++ AAAA R +NP ++V + P TE IY D+FF +DGVA ALD+ AR Y+
Sbjct: 526 KLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMD 585
Query: 550 ARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAP---YPVCTVRYFPS 606
RC +Y KPLLE+GT GT G+ V +P +TE+Y ++S+D P P+CT++ FP+
Sbjct: 586 RRCVYYRKPLLESGTLGTKGNVQVVIPFLTESY------SSSQDPPEKSIPICTLKNFPN 639
Query: 607 TAEHTLQWARHEFEELFRLSAETINHH---QQAHTSLADMDEPQTLTLLKPV-LGVLRVR 662
EHTLQWAR EFE LF+ AE +N + + + Q L +L+ V ++ R
Sbjct: 640 AIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQR 699
Query: 663 PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQD 722
PQ W DCV WA HW + I+QLL +FPP+++ G PFWSGPK+CP PL FD N
Sbjct: 700 PQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNP 759
Query: 723 THLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPD--PQQMAPIFASNLELASASA 780
HL YV+AAANL+AQ +GL GSQD A+ L+ + P+ P+ I S+ EL SA+A
Sbjct: 760 LHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANA 819
Query: 781 EFGPEQQKELNKALEVWSVGPPLK--PLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVN 838
+ +EL L P K P+ FEKDDDSNFH+DF+VAA++LR +NY IP +
Sbjct: 820 SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSAD 879
Query: 839 RAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMP 898
R +SK I G+IIPAIATTTAAV GL+ LELYKVV G R ++++ +L+LA + P
Sbjct: 880 RHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEP 939
Query: 899 FAPAIQTFHHLKWTSWDRLKVPAGQP---ERTLESLLAHLQEQHGLRVRILLHGSALLYA 955
A +++ +WT WDR +V QP E TL+ L + + +H L + +L G ++LY+
Sbjct: 940 LAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYS 999
Query: 956 AGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDD-EDTAFPPLHYEL 1012
K + L +TE+V +++ + R LVLEL C + ED P + Y +
Sbjct: 1000 FFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057
>gi|23510340 ubiquitin-activating enzyme E1 [Homo sapiens]
Length = 1058
Score = 862 bits (2228), Expect = 0.0
Identities = 474/1018 (46%), Positives = 644/1018 (63%), Gaps = 25/1018 (2%)
Query: 10 LDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCW 69
+DE LYSRQLYVLG AM+R+Q + VLVSGL+GLG E+AKN++L GV ++TLHD W
Sbjct: 50 IDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQW 109
Query: 70 SDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKL 129
+DL++QF L E+D+ ++RAE SQ LA+LN V V +TG + ED L FQVVVLT L
Sbjct: 110 ADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNTPL 169
Query: 130 EEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSP 189
E+QL+VG CH G+ + ADTRGL GQLFCDFGE+ + D +PL+A + +++ +P
Sbjct: 170 EDQLRVGEFCHNRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSAMVSMVTKDNP 229
Query: 190 GILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLR 249
G++T A H F GD V+FS ++GMVELN P I V + I DT+ FS Y+R
Sbjct: 230 GVVTCLDEAR-HGFESGDFVSFSEVQGMVELNGNQPMEIKVLGPYTFSICDTSNFSDYIR 288
Query: 250 GGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQ 309
GG +++VK PK + KSL +L +P V + LH F ALH+F HGRPP+
Sbjct: 289 GGIVSQVKVPKKISFKSLVASLAEPDFVVTDFAKFSRPAQLHIGFQALHQFCAQHGRPPR 348
Query: 310 PWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAA 369
P + DA +V LA+ + R + LDE L+R +A +AG L+P+ A +G +AA
Sbjct: 349 PRNEEDAAELVALAQAVN--ARALPAVQQNNLDEDLIRKLAYVAAGDLAPINAFIGGLAA 406
Query: 370 QEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEK 429
QEV+KA S KFMP+ QWLYFDAL+CLPED E+L + + C R +RYDGQ+AVFG+ QEK
Sbjct: 407 QEVMKACSGKFMPIMQWLYFDALECLPEDKEVL-TEDKCLQRQNRYDGQVAVFGSDLQEK 465
Query: 430 LRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVG 489
L +Q Y LVGAGAIGCELLK FA++GLG G G + V DMD IE+SNL+RQFLFR DV
Sbjct: 466 LGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEIIVTDMDTIEKSNLNRQFLFRPWDVT 525
Query: 490 RPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVA 549
+ K++ AAAA R +NP ++V + P TE IY D+FF +DGVA ALD+ AR Y+
Sbjct: 526 KLKSDTAAAAVRQMNPHIRVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMD 585
Query: 550 ARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAP---YPVCTVRYFPS 606
RC +Y KPLLE+GT GT G+ V +P +TE+Y ++S+D P P+CT++ FP+
Sbjct: 586 RRCVYYRKPLLESGTLGTKGNVQVVIPFLTESY------SSSQDPPEKSIPICTLKNFPN 639
Query: 607 TAEHTLQWARHEFEELFRLSAETINHH---QQAHTSLADMDEPQTLTLLKPV-LGVLRVR 662
EHTLQWAR EFE LF+ AE +N + + + Q L +L+ V ++ R
Sbjct: 640 AIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQR 699
Query: 663 PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQD 722
PQ W DCV WA HW + I+QLL +FPP+++ G PFWSGPK+CP PL FD N
Sbjct: 700 PQTWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNP 759
Query: 723 THLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPD--PQQMAPIFASNLELASASA 780
HL YV+AAANL+AQ +GL GSQD A+ L+ + P+ P+ I S+ EL SA+A
Sbjct: 760 LHLDYVMAAANLFAQTYGLTGSQDRAAVATFLQSVQVPEFTPKSGVKIHVSDQELQSANA 819
Query: 781 EFGPEQQKELNKALEVWSVGPPLK--PLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVN 838
+ +EL L P K P+ FEKDDDSNFH+DF+VAA++LR +NY IP +
Sbjct: 820 SVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPSAD 879
Query: 839 RAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMP 898
R +SK I G+IIPAIATTTAAV GL+ LELYKVV G R ++++ +L+LA + P
Sbjct: 880 RHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRQLDSYKNGFLNLALPFFGFSEP 939
Query: 899 FAPAIQTFHHLKWTSWDRLKVPAGQP---ERTLESLLAHLQEQHGLRVRILLHGSALLYA 955
A +++ +WT WDR +V QP E TL+ L + + +H L + +L G ++LY+
Sbjct: 940 LAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYS 999
Query: 956 AGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCEGDD-EDTAFPPLHYEL 1012
K + L +TE+V +++ + R LVLEL C + ED P + Y +
Sbjct: 1000 FFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTI 1057
>gi|150417996 ubiquitin-activating enzyme E1-like 2 [Homo sapiens]
Length = 1052
Score = 583 bits (1503), Expect = e-166
Identities = 385/1037 (37%), Positives = 565/1037 (54%), Gaps = 58/1037 (5%)
Query: 6 ASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPH 65
AS +D+ LYSRQ YVLG AMQ++ + V +SG+ GLG E+AKNLVL G+ ++T+HD
Sbjct: 35 ASVEIDDALYSRQRYVLGDTAMQKMAKSHVFLSGMGGLGLEIAKNLVLAGIKAVTIHDTE 94
Query: 66 PTCWSDLAAQFLLSEQDL--ERSRAEASQELLAQLNRAVQVV---VHTGDITEDLLLD-F 119
DL F LSE D+ +R+RAEA + +A+LN V V V + T+ LD +
Sbjct: 95 KCQAWDLGTNFFLSEDDVVNKRNRAEAVLKHIAELNPYVHVTSSSVPFNETTDLSFLDKY 154
Query: 120 QVVVLTAAKLEEQLKVGTLCHKH--GVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPL 177
Q VVLT KL Q K+ C + F++AD G+ +LFCDFG++F V D T EP
Sbjct: 155 QCVVLTEMKLPLQKKINDFCRSQCPPIKFISADVHGIWSRLFCDFGDEFEVLDTTGEEPK 214
Query: 178 TAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLE 237
I +I+Q +PGI+T + + H G +TF I GM LN + I V S
Sbjct: 215 EIFISNITQANPGIVTCLEN-HPHKLETGQFLTFREINGMTGLNG-SIQQITVISPFSFS 272
Query: 238 IGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCAL 297
IGDTT YL GG +VK PKTV +SL+ L P + +H A AL
Sbjct: 273 IGDTTELEPYLHGGIAVQVKTPKTVFFESLERQLKHPKCLIVDFSNPEAPLEIHTAMLAL 332
Query: 298 HKFQHLHGRPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVL 357
+FQ + R P D+E ++ LA + + EE+P ++ +V ++ ++ G L
Sbjct: 333 DQFQEKYSRKPNVGCQQDSEELLKLATSIS--ETLEEKP---DVNADIVHWLSWTAQGFL 387
Query: 358 SPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDG 417
SP+ A +G VA+QEVLKA++ KF PL QWLY +A D + G+ P E+ RG RYD
Sbjct: 388 SPLAAAVGGVASQEVLKAVTGKFSPLCQWLYLEAADIVESLGK--PECEEFLPRGDRYDA 445
Query: 418 QIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGL-TVVDMDHIERSN 476
A G +KL+ + LVG GAIGCE+LK FAL+G+G G+ TV D D IE+SN
Sbjct: 446 LRACIGDTLCQKLQNLNIFLVGCGAIGCEMLKNFALLGVGTSKEKGMITVTDPDLIEKSN 505
Query: 477 LSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVA 536
L+RQFLFR + +PK+ AA A +N +++ + PTTE IY D F+++ D +
Sbjct: 506 LNRQFLFRPHHIQKPKSYTAADATLKINSQIKIDAHLNKVCPTTETIYNDEFYTKQDVII 565
Query: 537 AALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPY 596
ALD+ +ARRYV +RC L+PLL++GT GT G V +PH+TE+Y + E
Sbjct: 566 TALDNVEARRYVDSRCLANLRPLLDSGTMGTKGHTEVIVPHLTESYNSHRDPPEEE---I 622
Query: 597 PVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQAHTS----LADMDEPQTLTLL 652
P CT++ FP+ EHT+QWAR +FE F N Q ++S L + +L
Sbjct: 623 PFCTLKSFPAAIEHTIQWARDKFESSFSHKPSLFNKFWQTYSSAEEVLQKIQSGHSLEGC 682
Query: 653 KPVLGVLRVRPQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCP 712
V+ +L RP+NW CV A ++ F++ QLL FP + L+DG+ FW PK+ P
Sbjct: 683 FQVIKLLSRRPRNWSQCVELARLKFEKYFNHKALQLLHCFPLDIRLKDGSLFWQSPKRPP 742
Query: 713 QPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPI---- 768
P++FD N+ HL ++ AA LYA ++ +P +++ + LL +L + Q+ P
Sbjct: 743 SPIKFDLNEPLHLSFLQNAAKLYATVYCIPFAEEDLSADALLNILSEVKIQEFKPSNKVV 802
Query: 769 ----FASNLELASASAEFGPEQQKELNKAL---EVWSVGPPLKPLMFEKDDDSNFHVDFV 821
A + S+E +L KA+ E + L FEKDDD N H+DF+
Sbjct: 803 QTDETARKPDHVPISSEDERNAIFQLEKAILSNEATKSDLQMAVLSFEKDDDHNGHIDFI 862
Query: 822 VAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAF 881
AA++LR + Y I P +R ++KRI G+IIPAIATTTA V+GL+ LE+ KV G P A+
Sbjct: 863 TAASNLRAKMYSIEPADRFKTKRIAGKIIPAIATTTATVSGLVALEMIKVTGG-YPFEAY 921
Query: 882 RHSYLHLAENYLIRYMPFAPAIQT-----FHHLKWTSWDRLKVPAGQPERTLESLLAHLQ 936
++ +L+LA I + F + + + +T WDR V G+ + TL + ++
Sbjct: 922 KNCFLNLA----IPIVVFTETTEVRKTKIRNGISFTIWDRWTV-HGKEDFTLLDFINAVK 976
Query: 937 EQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSC 996
E++G+ +++ G +LY A+ L L + +LV+ P ++ + L +S
Sbjct: 977 EKYGIEPTMVVQGVKMLYVP--VMPGHAKRLKLTMHKLVK------PTTEKKYVDLTVSF 1028
Query: 997 EGD---DEDTAFPPLHY 1010
D DED PP+ Y
Sbjct: 1029 APDIDGDEDLPGPPVRY 1045
>gi|4885649 SUMO-1 activating enzyme subunit 2 [Homo sapiens]
Length = 640
Score = 131 bits (329), Expect = 4e-30
Identities = 131/443 (29%), Positives = 189/443 (42%), Gaps = 59/443 (13%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEV 495
L+VGAG IGCELLK L G + ++D+D I+ SNL+RQFLF+ + VGR KA+V
Sbjct: 21 LVVGAGGIGCELLKNLVLTGFSH-----IDLIDLDTIDVSNLNRQFLFQKKHVGRSKAQV 75
Query: 496 AAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHY 555
A + P ++ D Y FF + V ALD+ AR +V C
Sbjct: 76 AKESVLQFYPKANIVAYH---DSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAA 132
Query: 556 LKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWA 615
PL+E+GT+G G T VTE Y +P CT+R PS H + WA
Sbjct: 133 DVPLIESGTAGYLGQVTTIKKGVTECYECHPKPT---QRTFPGCTIRNTPSEPIHCIVWA 189
Query: 616 RHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQ-DCVAWAL 674
++ LF + Q+ AD + +P R R N D +
Sbjct: 190 KY----LFNQLFGEEDADQEVSPDRADPE-----AAWEPTEAEARARASNEDGDIKRIST 240
Query: 675 GHWKLCFHYG-IKQLLRHFPPN-KVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAA 732
W Y +K + F + + L W K P PL++ A
Sbjct: 241 KEWAKSTGYDPVKLFTKLFKDDIRYLLTMDKLWRKRKP-PVPLDW--------------A 285
Query: 733 NLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLE-LASASAEFGPEQQKELN 791
+ +Q S + LK D + A +F+ ++E L AE G +
Sbjct: 286 EVQSQGEETNASDQQNEPQLGLKDQQVLDVKSYARLFSKSIETLRVHLAEKGDGAE---- 341
Query: 792 KALEVWSVGPPLKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIP 851
L+++KDD S +DFV +AA+LR + + +R K + G IIP
Sbjct: 342 --------------LIWDKDDPSA--MDFVTSAANLRMHIFSMNMKSRFDIKSMAGNIIP 385
Query: 852 AIATTTAAVAGLLGLELYKVVSG 874
AIATT A +AGL+ LE K++SG
Sbjct: 386 AIATTNAVIAGLIVLEGLKILSG 408
Score = 55.5 bits (132), Expect = 3e-07
Identities = 38/136 (27%), Positives = 63/136 (46%), Gaps = 5/136 (3%)
Query: 28 QRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSR 87
+ + G RVLV G G+G E+ KNLVL G + L D S+L QFL ++ + RS+
Sbjct: 13 EAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQKKHVGRSK 72
Query: 88 AEASQELLAQLNRAVQVVVH-----TGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKH 142
A+ ++E + Q +V + D + F +V+ + V +C
Sbjct: 73 AQVAKESVLQFYPKANIVAYHDSIMNPDYNVEFFRQFILVMNALDNRAARNHVNRMCLAA 132
Query: 143 GVCFLAADTRGLVGQL 158
V + + T G +GQ+
Sbjct: 133 DVPLIESGTAGYLGQV 148
>gi|225543288 SUMO1 activating enzyme subunit 1 isoform c [Homo
sapiens]
Length = 266
Score = 111 bits (277), Expect = 4e-24
Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)
Query: 15 YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74
Y RQ+ + G A +R++ +RVL+ GL+GLGAE+AKNL+L GV LT+ D D A
Sbjct: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
Query: 75 QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131
QFL+ + R+RAEAS E LN V V V T DI E F V LT +
Sbjct: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182
+KV +CHK+ + F D G G F + GE V++ T+ ++ ++
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189
Score = 63.9 bits (154), Expect = 7e-10
Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472
++YD QI ++G Q++LR LLVG +G E+ K L G+ GLT++D + +
Sbjct: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
Query: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532
+ QFL R+ VGR +AE + A+ LNP + V T ++ E +FF++
Sbjct: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
Query: 533 DGV 535
D V
Sbjct: 127 DAV 129
>gi|225543285 SUMO1 activating enzyme subunit 1 isoform b [Homo
sapiens]
Length = 299
Score = 111 bits (277), Expect = 4e-24
Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)
Query: 15 YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74
Y RQ+ + G A +R++ +RVL+ GL+GLGAE+AKNL+L GV LT+ D D A
Sbjct: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
Query: 75 QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131
QFL+ + R+RAEAS E LN V V V T DI E F V LT +
Sbjct: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182
+KV +CHK+ + F D G G F + GE V++ T+ ++ ++
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189
Score = 63.9 bits (154), Expect = 7e-10
Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472
++YD QI ++G Q++LR LLVG +G E+ K L G+ GLT++D + +
Sbjct: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
Query: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532
+ QFL R+ VGR +AE + A+ LNP + V T ++ E +FF++
Sbjct: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
Query: 533 DGV 535
D V
Sbjct: 127 DAV 129
>gi|4885585 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 111 bits (277), Expect = 4e-24
Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)
Query: 15 YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74
Y RQ+ + G A +R++ +RVL+ GL+GLGAE+AKNL+L GV LT+ D D A
Sbjct: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
Query: 75 QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131
QFL+ + R+RAEAS E LN V V V T DI E F V LT +
Sbjct: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182
+KV +CHK+ + F D G G F + GE V++ T+ ++ ++
Sbjct: 139 IVKVDQICHKNSIKFFTGDVFGYHGYTFANLGEHEFVEEKTKVAKVSQGVE 189
Score = 63.9 bits (154), Expect = 7e-10
Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472
++YD QI ++G Q++LR LLVG +G E+ K L G+ GLT++D + +
Sbjct: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
Query: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532
+ QFL R+ VGR +AE + A+ LNP + V T ++ E +FF++
Sbjct: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
Query: 533 DGV 535
D V
Sbjct: 127 DAV 129
Score = 34.7 bits (78), Expect = 0.47
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 357 LSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDAL 392
++P+ A++G + AQE++KA+S++ P + + +FD +
Sbjct: 299 MAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|7705473 SUMO1 activating enzyme subunit 1 isoform a [Homo
sapiens]
Length = 346
Score = 111 bits (277), Expect = 4e-24
Identities = 65/171 (38%), Positives = 92/171 (53%), Gaps = 3/171 (1%)
Query: 15 YSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAA 74
Y RQ+ + G A +R++ +RVL+ GL+GLGAE+AKNL+L GV LT+ D D A
Sbjct: 19 YDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVKGLTMLDHEQVTPEDPGA 78
Query: 75 QFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDI---TEDLLLDFQVVVLTAAKLEE 131
QFL+ + R+RAEAS E LN V V V T DI E F V LT +
Sbjct: 79 QFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPESFFTQFDAVCLTCCSRDV 138
Query: 132 QLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQ 182
+KV +CHK+ + F D G G F + GE V++ T+ ++ ++
Sbjct: 139 IVKVDQICHKNSIKFFTGDAFGYHGYTFANLGEHEFVEEETDVAKVSHGVE 189
Score = 63.9 bits (154), Expect = 7e-10
Identities = 41/123 (33%), Positives = 65/123 (52%), Gaps = 10/123 (8%)
Query: 413 SRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHI 472
++YD QI ++G Q++LR LLVG +G E+ K L G+ GLT++D + +
Sbjct: 17 AQYDRQIRLWGLEAQKRLRASRVLLVGLKGLGAEIAKNLILAGVK-----GLTMLDHEQV 71
Query: 473 ERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRV 532
+ QFL R+ VGR +AE + A+ LNP + V T ++ E +FF++
Sbjct: 72 TPEDPGAQFLIRTGSVGRNRAEASLERAQNLNPMVDVKVDTEDIEKKPE-----SFFTQF 126
Query: 533 DGV 535
D V
Sbjct: 127 DAV 129
Score = 34.7 bits (78), Expect = 0.47
Identities = 12/36 (33%), Positives = 27/36 (75%)
Query: 357 LSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDAL 392
++P+ A++G + AQE++KA+S++ P + + +FD +
Sbjct: 299 MAPVCAVVGGILAQEIVKALSQRDPPHNNFFFFDGM 334
>gi|38045944 ubiquitin-activating enzyme 3 isoform 2 [Homo sapiens]
Length = 449
Score = 106 bits (265), Expect = 1e-22
Identities = 66/193 (34%), Positives = 96/193 (49%), Gaps = 23/193 (11%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEV 495
L++GAG +GCELLK AL G + V+DMD I+ SNL+RQFLFR +D+GRPKAEV
Sbjct: 59 LVIGAGGLGCELLKNLALSGFRQ-----IHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEV 113
Query: 496 AAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHY 555
AA P+ V+P + + D F+ + + LDS ARR++
Sbjct: 114 AAEFLNDRVPNCNVVPHFNKIQD-----FNDTFYRQFHIIVCGLDSIIARRWINGMLISL 168
Query: 556 LK------------PLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRY 603
L PL++ GT G G+A V +P +T + +P+CT+
Sbjct: 169 LNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQ-VNFPMCTIAS 227
Query: 604 FPSTAEHTLQWAR 616
P EH +++ R
Sbjct: 228 MPRLPEHCIEYVR 240
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 34 RVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQE 93
+VLV G GLG E+ KNL L G + + D S+L QFL +D+ R +AE + E
Sbjct: 57 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAE 116
Query: 94 LLAQLNRAVQVVVHTG---DITEDLLLDFQVVV 123
L VV H D + F ++V
Sbjct: 117 FLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 149
Score = 39.7 bits (91), Expect = 0.014
Identities = 18/63 (28%), Positives = 34/63 (53%)
Query: 811 DDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYK 870
D D H+ ++ + R Y I V ++ +V +IIPA+A+T A +A + E++K
Sbjct: 257 DGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFK 316
Query: 871 VVS 873
+ +
Sbjct: 317 IAT 319
>gi|38045942 ubiquitin-activating enzyme 3 isoform 1 [Homo sapiens]
Length = 463
Score = 106 bits (265), Expect = 1e-22
Identities = 66/193 (34%), Positives = 96/193 (49%), Gaps = 23/193 (11%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEV 495
L++GAG +GCELLK AL G + V+DMD I+ SNL+RQFLFR +D+GRPKAEV
Sbjct: 73 LVIGAGGLGCELLKNLALSGFRQ-----IHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEV 127
Query: 496 AAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHY 555
AA P+ V+P + + D F+ + + LDS ARR++
Sbjct: 128 AAEFLNDRVPNCNVVPHFNKIQD-----FNDTFYRQFHIIVCGLDSIIARRWINGMLISL 182
Query: 556 LK------------PLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRY 603
L PL++ GT G G+A V +P +T + +P+CT+
Sbjct: 183 LNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQ-VNFPMCTIAS 241
Query: 604 FPSTAEHTLQWAR 616
P EH +++ R
Sbjct: 242 MPRLPEHCIEYVR 254
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 3/93 (3%)
Query: 34 RVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQE 93
+VLV G GLG E+ KNL L G + + D S+L QFL +D+ R +AE + E
Sbjct: 71 KVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDIGRPKAEVAAE 130
Query: 94 LLAQLNRAVQVVVHTG---DITEDLLLDFQVVV 123
L VV H D + F ++V
Sbjct: 131 FLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIV 163
Score = 39.7 bits (91), Expect = 0.014
Identities = 18/63 (28%), Positives = 34/63 (53%)
Query: 811 DDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYK 870
D D H+ ++ + R Y I V ++ +V +IIPA+A+T A +A + E++K
Sbjct: 271 DGDDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPAVASTNAVIAAVCATEVFK 330
Query: 871 VVS 873
+ +
Sbjct: 331 IAT 333
>gi|4502169 NEDD8 activating enzyme E1 subunit 1 isoform a [Homo
sapiens]
Length = 534
Score = 73.2 bits (178), Expect = 1e-12
Identities = 52/162 (32%), Positives = 74/162 (45%), Gaps = 16/162 (9%)
Query: 8 KLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPT 67
KLL E+ Y RQL + G + ++ A V + G E+ KNLVL G+GS T+ D +
Sbjct: 6 KLLKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQV 65
Query: 68 CWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDL---LLD------ 118
D F L + ++RAEA+ E L +LN V +G E+ LLD
Sbjct: 66 SGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFF 120
Query: 119 --FQVVVLTAAKLEEQLKVGTLCHKHGVCFLAADTRGLVGQL 158
F VVV T L++ + + L T GLVG +
Sbjct: 121 CRFTVVVATQLPESTSLRLADVLWNSQIPLLICRTYGLVGYM 162
Score = 53.9 bits (128), Expect = 7e-07
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 5/98 (5%)
Query: 410 LRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDM 469
L+ +YD Q+ ++G QE L H L+ A A G E+LK L G+G+ T++D
Sbjct: 8 LKEQKYDRQLRLWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGS-----FTIIDG 62
Query: 470 DHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDL 507
+ + + F + +G+ +AE A + LN D+
Sbjct: 63 NQVSGEDAGNNFFLQRSSIGKNRAEAAMEFLQELNSDV 100
>gi|7657339 molybdenum cofactor synthesis 3 [Homo sapiens]
Length = 460
Score = 71.2 bits (173), Expect = 4e-12
Identities = 59/177 (33%), Positives = 79/177 (44%), Gaps = 14/177 (7%)
Query: 403 PSPEDCALRGS---RYDGQIAV--FGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLG 457
P P AL RY Q+ + G Q +L L+VG G +GC L + A G+G
Sbjct: 48 PLPPKAALSRDEILRYSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVG 107
Query: 458 AGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQVIPLTYPLD 517
L +VD D +E SNL+RQ L G+ KA AAA+ R LN ++ +P T L
Sbjct: 108 R-----LGLVDYDVVEMSNLARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALT 162
Query: 518 PTTEHIYGDNFFSRVDGVAAALDSFQARRYVAARCTHYLKPLLEAGTSGTWGSATVF 574
P T + R D VA D+ R V C +PL+ A G TV+
Sbjct: 163 PAT----ALDLVRRYDVVADCSDNVPTRYLVNDACVLAGRPLVSASALRFEGQITVY 215
Score = 53.5 bits (127), Expect = 1e-06
Identities = 48/150 (32%), Positives = 71/150 (47%), Gaps = 6/150 (4%)
Query: 15 YSRQLYV--LGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDL 72
YSRQL + LG R+ A VL+ G GLG +A+ L GVG L L D S+L
Sbjct: 63 YSRQLVLPELGVHGQLRLGTACVLIVGCGGLGCPLAQYLAAAGVGRLGLVDYDVVEMSNL 122
Query: 73 AAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITE----DLLLDFQVVVLTAAK 128
A Q L E +++A ++ L +LN AV+ V +T +T DL+ + VV +
Sbjct: 123 ARQVLHGEALAGQAKAFSAAASLRRLNSAVECVPYTQALTPATALDLVRRYDVVADCSDN 182
Query: 129 LEEQLKVGTLCHKHGVCFLAADTRGLVGQL 158
+ + V C G ++A GQ+
Sbjct: 183 VPTRYLVNDACVLAGRPLVSASALRFEGQI 212
>gi|66363686 NEDD8 activating enzyme E1 subunit 1 isoform b [Homo
sapiens]
Length = 528
Score = 59.7 bits (143), Expect = 1e-08
Identities = 44/147 (29%), Positives = 64/147 (43%), Gaps = 16/147 (10%)
Query: 23 GSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQD 82
G + ++ A V + G E+ KNLVL G+GS T+ D + D F L
Sbjct: 15 GDHGQEALESAHVCLINATATGTEILKNLVLPGIGSFTIIDGNQVSGEDAGNNFFLQRSS 74
Query: 83 LERSRAEASQELLAQLNRAVQVVVHTGDITEDL---LLD--------FQVVVLTAAKLEE 131
+ ++RAEA+ E L +LN V +G E+ LLD F VVV T
Sbjct: 75 IGKNRAEAAMEFLQELNSDV-----SGSFVEESPENLLDNDPSFFCRFTVVVATQLPEST 129
Query: 132 QLKVGTLCHKHGVCFLAADTRGLVGQL 158
L++ + + L T GLVG +
Sbjct: 130 SLRLADVLWNSQIPLLICRTYGLVGYM 156
Score = 45.1 bits (105), Expect = 3e-04
Identities = 25/87 (28%), Positives = 42/87 (48%), Gaps = 5/87 (5%)
Query: 421 VFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQ 480
++G QE L H L+ A A G E+LK L G+G+ T++D + + +
Sbjct: 13 LWGDHGQEALESAHVCLINATATGTEILKNLVLPGIGS-----FTIIDGNQVSGEDAGNN 67
Query: 481 FLFRSQDVGRPKAEVAAAAARGLNPDL 507
F + +G+ +AE A + LN D+
Sbjct: 68 FFLQRSSIGKNRAEAAMEFLQELNSDV 94
>gi|38327032 ubiquitin-activating enzyme 5 isoform 2 [Homo sapiens]
Length = 348
Score = 50.4 bits (119), Expect = 8e-06
Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 428 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD 487
EK+R +VG G +G ++ G+G L + D D +E +N++R F F+
Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGK-----LLLFDYDKVELANMNRLF-FQPHQ 66
Query: 488 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSR-----------VDGVA 536
G K + A R +NPD+ Y + T E+ +F R VD V
Sbjct: 67 AGLSKVQAAEHTLRNINPDVLFEVHNYNIT-TVENF--QHFMDRISNGGLEEGKPVDLVL 123
Query: 537 AALDSFQARRYVAARCTHYLKPLLEAGTS 565
+ +D+F+AR + C + +E+G S
Sbjct: 124 SCVDNFEARMTINTACNELGQTWMESGVS 152
Score = 33.1 bits (74), Expect = 1.4
Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 28 QRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSR 87
++I+ V + G+ G+G+ A+ L G+G L L D +++ F Q S+
Sbjct: 13 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPHQ-AGLSK 71
Query: 88 AEASQELLAQLNRAVQVVVHTGDIT 112
+A++ L +N V VH +IT
Sbjct: 72 VQAAEHTLRNINPDVLFEVHNYNIT 96
>gi|13376212 ubiquitin-activating enzyme 5 isoform 1 [Homo sapiens]
Length = 404
Score = 50.4 bits (119), Expect = 8e-06
Identities = 40/149 (26%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 428 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQD 487
EK+R +VG G +G ++ G+G L + D D +E +N++R F F+
Sbjct: 69 EKIRTFAVAIVGVGGVGSVTAEMLTRCGIGK-----LLLFDYDKVELANMNRLF-FQPHQ 122
Query: 488 VGRPKAEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSR-----------VDGVA 536
G K + A R +NPD+ Y + T E+ +F R VD V
Sbjct: 123 AGLSKVQAAEHTLRNINPDVLFEVHNYNIT-TVENF--QHFMDRISNGGLEEGKPVDLVL 179
Query: 537 AALDSFQARRYVAARCTHYLKPLLEAGTS 565
+ +D+F+AR + C + +E+G S
Sbjct: 180 SCVDNFEARMTINTACNELGQTWMESGVS 208
Score = 35.0 bits (79), Expect = 0.36
Identities = 28/110 (25%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 6 ASKLLDEELYSRQLYVLGSPAM---QRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLH 62
+S+++D YSR + + + ++I+ V + G+ G+G+ A+ L G+G L L
Sbjct: 44 SSEVVDSNPYSRLMALKRMGIVSDYEKIRTFAVAIVGVGGVGSVTAEMLTRCGIGKLLLF 103
Query: 63 DPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDIT 112
D +++ F Q S+ +A++ L +N V VH +IT
Sbjct: 104 DYDKVELANMNRLFFQPHQ-AGLSKVQAAEHTLRNINPDVLFEVHNYNIT 152
>gi|222144229 APG7 autophagy 7-like isoform c [Homo sapiens]
Length = 623
Score = 36.6 bits (83), Expect = 0.12
Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDV---GRPK 492
LL+GAG +GC + + L+G G + +T VD I SN RQ L+ +D G+PK
Sbjct: 320 LLLGAGTLGCNVAR--TLMGWGVRH---ITFVDNAKISYSNPVRQPLYEFEDCLGGGKPK 374
Query: 493 AEVAAAAARGLNP 505
A AA + + P
Sbjct: 375 ALAAADRLQKIFP 387
>gi|222144227 APG7 autophagy 7-like isoform b [Homo sapiens]
Length = 676
Score = 36.6 bits (83), Expect = 0.12
Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDV---GRPK 492
LL+GAG +GC + + L+G G + +T VD I SN RQ L+ +D G+PK
Sbjct: 359 LLLGAGTLGCNVAR--TLMGWGVRH---ITFVDNAKISYSNPVRQPLYEFEDCLGGGKPK 413
Query: 493 AEVAAAAARGLNP 505
A AA + + P
Sbjct: 414 ALAAADRLQKIFP 426
>gi|5453668 APG7 autophagy 7-like isoform a [Homo sapiens]
Length = 703
Score = 36.6 bits (83), Expect = 0.12
Identities = 27/73 (36%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 436 LLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDV---GRPK 492
LL+GAG +GC + + L+G G + +T VD I SN RQ L+ +D G+PK
Sbjct: 359 LLLGAGTLGCNVAR--TLMGWGVRH---ITFVDNAKISYSNPVRQPLYEFEDCLGGGKPK 413
Query: 493 AEVAAAAARGLNP 505
A AA + + P
Sbjct: 414 ALAAADRLQKIFP 426
>gi|56711322 ring finger protein 43 [Homo sapiens]
Length = 783
Score = 32.7 bits (73), Expect = 1.8
Identities = 30/98 (30%), Positives = 47/98 (47%), Gaps = 13/98 (13%)
Query: 261 TVRHKSLDTALLQPHVVAQSSQEVHHAHCLHQAFCALHKFQHLHGRPPQPWDPVDAETVV 320
T R +SLD+ + P Q S VH+ H + +FQ HGR P P ET
Sbjct: 527 TSRPRSLDSVV--PTGETQVSSHVHYHRHRHHHY--KKRFQW-HGRKPGP------ET-- 573
Query: 321 GLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLS 358
G+ + P+ RT+ +P D+ + R+ + + +G LS
Sbjct: 574 GVPQSRPPIPRTQPQPEPPSPDQQVTRSNSAAPSGRLS 611
>gi|145312265 endoplasmic reticulum to nucleus signalling 2 [Homo
sapiens]
Length = 974
Score = 32.3 bits (72), Expect = 2.3
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 722 DTHLLYVLAAANLYAQMH-GLPGSQDWTALRELLKLLPQPDPQQMAPIFASN----LELA 776
D L L A +H G+PG++ W A ELL+LLP P IF++ L+
Sbjct: 708 DFGLCKKLPAGRCSFSLHSGIPGTEGWMA-PELLQLLPPDSPTSAVDIFSAGCVFYYVLS 766
Query: 777 SASAEFGPEQQKELN 791
S FG ++ N
Sbjct: 767 GGSHPFGDSLYRQAN 781
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 32.0 bits (71), Expect = 3.0
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 748 TALRELLKLLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPLKPLM 807
T EL+ P D +AP+F LE A F ++ + L E+W G P+ P M
Sbjct: 180 TPTPELISKKPPDDTTALAPLFGPPLESA-----FDEQKTEVLLDQPEIWGSGQPINPSM 234
>gi|40217823 SLIT and NTRK-like family, member 5 [Homo sapiens]
Length = 958
Score = 31.2 bits (69), Expect = 5.2
Identities = 34/120 (28%), Positives = 50/120 (41%), Gaps = 20/120 (16%)
Query: 94 LLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAKLEEQLKVGTLCHKHGVC-----FLA 148
+L QL +Q+ +H D D D + L EQLKVG L + +C F
Sbjct: 548 VLDQLKSLIQIDLH--DNPWDCTCDIVGMKLWV----EQLKVGVLVDEV-ICKAPKKFAE 600
Query: 149 ADTRGLVGQLFCDFGEDFTVQDPTEAE--------PLTAAIQHISQGSPGILTLRKGANT 200
D R + +L C D V PT + +T A++ S G+P L GA++
Sbjct: 601 TDMRSIKSELLCPDYSDVVVSTPTPSSIQVPARTSAVTPAVRLNSTGAPASLGAGGGASS 660
>gi|195963410 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 1 [Homo sapiens]
Length = 415
Score = 30.8 bits (68), Expect = 6.7
Identities = 16/48 (33%), Positives = 25/48 (52%)
Query: 756 LLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPL 803
L P PD + ++ +F+S+L + S+ P + LE S GPPL
Sbjct: 338 LSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPL 385
>gi|32698970 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 2 [Homo sapiens]
Length = 312
Score = 30.8 bits (68), Expect = 6.7
Identities = 16/48 (33%), Positives = 25/48 (52%)
Query: 756 LLPQPDPQQMAPIFASNLELASASAEFGPEQQKELNKALEVWSVGPPL 803
L P PD + ++ +F+S+L + S+ P + LE S GPPL
Sbjct: 235 LSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSGGPPL 282
>gi|148727368 bromodomain and PHD finger containing, 3 [Homo sapiens]
Length = 1205
Score = 30.8 bits (68), Expect = 6.7
Identities = 34/127 (26%), Positives = 53/127 (41%), Gaps = 16/127 (12%)
Query: 896 YMPFAPAIQTFHHLKWTSWDRLKVPAGQ----PERTLESLLAHLQEQHGL--------RV 943
++P +P ++ F+ W D + +P + PE L+ LL L + RV
Sbjct: 709 HLPESPKLEDFYRFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGARTRRV 768
Query: 944 RILLHG-SALLYAAGWSPEKQAQHLPLRVT--ELVQQLTGQAPAPGQRVLVLELSCEGDD 1000
R+L +AL P Q L V+ EL G A A ++ L E +GD
Sbjct: 769 RLLRREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDA-AVLEQALQEEPEDDGDR 827
Query: 1001 EDTAFPP 1007
+D+ PP
Sbjct: 828 DDSKLPP 834
>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
Length = 818
Score = 30.4 bits (67), Expect = 8.8
Identities = 17/50 (34%), Positives = 27/50 (54%), Gaps = 2/50 (4%)
Query: 957 GWSPEKQAQHL--PLRVTELVQQLTGQAPAPGQRVLVLELSCEGDDEDTA 1004
GW+ + A +L PLR + +++T PAP + L+L EG E+ A
Sbjct: 230 GWNGDNSAGYLTVPLRPLTIGKEVTMDVPAPNAPGVRLQLKAEGCPEELA 279
>gi|239755087 PREDICTED: similar to zinc finger protein 598 [Homo
sapiens]
Length = 159
Score = 30.4 bits (67), Expect = 8.8
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 13/86 (15%)
Query: 716 EFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLEL 775
EF ++ +++AA Y GL G ELL LLP QQ E+
Sbjct: 32 EFKSHSGEFRQGLISAAQYYKSCRGLLGENFQKVFNELLVLLPDTAKQQ---------EI 82
Query: 776 ASASAEFGPEQQ----KELNKALEVW 797
SA +FG ++ K N W
Sbjct: 83 LSAHTDFGNREKTLSTKSKNNKKSAW 108
>gi|239749606 PREDICTED: similar to zinc finger protein 598 [Homo
sapiens]
Length = 159
Score = 30.4 bits (67), Expect = 8.8
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 13/86 (15%)
Query: 716 EFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLEL 775
EF ++ +++AA Y GL G ELL LLP QQ E+
Sbjct: 32 EFKSHSGEFRQGLISAAQYYKSCRGLLGENFQKVFNELLVLLPDTAKQQ---------EI 82
Query: 776 ASASAEFGPEQQ----KELNKALEVW 797
SA +FG ++ K N W
Sbjct: 83 LSAHTDFGNREKTLSTKSKNNKKSAW 108
>gi|239743874 PREDICTED: similar to zinc finger protein 598 [Homo
sapiens]
Length = 186
Score = 30.4 bits (67), Expect = 8.8
Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 13/86 (15%)
Query: 716 EFDTNQDTHLLYVLAAANLYAQMHGLPGSQDWTALRELLKLLPQPDPQQMAPIFASNLEL 775
EF ++ +++AA Y GL G ELL LLP QQ E+
Sbjct: 59 EFKSHSGEFRQGLISAAQYYKSCRGLLGENFQKVFNELLVLLPDTAKQQ---------EI 109
Query: 776 ASASAEFGPEQQ----KELNKALEVW 797
SA +FG ++ K N W
Sbjct: 110 LSAHTDFGNREKTLSTKSKNNKKSAW 135
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,157,418
Number of Sequences: 37866
Number of extensions: 1959100
Number of successful extensions: 4911
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 4804
Number of HSP's gapped (non-prelim): 51
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.