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Search of human proteins with 38045908
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
(1724 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens] 3467 0.0
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 3351 0.0
gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens] 3286 0.0
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 3170 0.0
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 826 0.0
gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 826 0.0
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 825 0.0
gi|21264602 laminin alpha 5 [Homo sapiens] 760 0.0
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 431 e-120
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 430 e-120
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 405 e-112
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 139 2e-32
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 134 6e-31
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 134 1e-30
gi|143770880 laminin, beta 4 [Homo sapiens] 127 7e-29
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 126 2e-28
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 122 3e-27
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 115 4e-25
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 114 6e-25
gi|93204871 netrin 4 [Homo sapiens] 105 5e-22
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 102 3e-21
gi|219842266 usherin isoform B [Homo sapiens] 97 1e-19
gi|219842259 usherin isoform A [Homo sapiens] 97 1e-19
gi|5453810 netrin 3 [Homo sapiens] 96 4e-19
gi|148613884 netrin 1 [Homo sapiens] 94 1e-18
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 88 6e-17
gi|24308065 netrin 5 [Homo sapiens] 87 1e-16
gi|58530840 desmoplakin isoform I [Homo sapiens] 86 3e-16
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 82 3e-15
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 82 3e-15
>gi|38045908 laminin alpha 3 subunit isoform 2 [Homo sapiens]
Length = 1724
Score = 3467 bits (8991), Expect = 0.0
Identities = 1724/1724 (100%), Positives = 1724/1724 (100%)
Query: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS
Sbjct: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
Query: 61 PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG 120
PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG
Sbjct: 61 PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG 120
Query: 121 SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC
Sbjct: 121 SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
Query: 181 NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG 240
NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG
Sbjct: 181 NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG 240
Query: 241 LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA 300
LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA
Sbjct: 241 LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA 300
Query: 301 QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSRE 360
QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSRE
Sbjct: 301 QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSRE 360
Query: 361 WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN 420
WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN
Sbjct: 361 WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN 420
Query: 421 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 480
EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS
Sbjct: 421 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 480
Query: 481 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL 540
SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL
Sbjct: 481 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL 540
Query: 541 QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK 600
QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK
Sbjct: 541 QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK 600
Query: 601 EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL 660
EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL
Sbjct: 601 EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL 660
Query: 661 RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK 720
RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK
Sbjct: 661 RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK 720
Query: 721 KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV 780
KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV
Sbjct: 721 KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV 780
Query: 781 PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI 840
PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI
Sbjct: 781 PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI 840
Query: 841 GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS 900
GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS
Sbjct: 841 GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS 900
Query: 901 SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE 960
SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE
Sbjct: 901 SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE 960
Query: 961 NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT 1020
NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT
Sbjct: 961 NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT 1020
Query: 1021 VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL 1080
VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL
Sbjct: 1021 VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL 1080
Query: 1081 QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR 1140
QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR
Sbjct: 1081 QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR 1140
Query: 1141 LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH 1200
LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH
Sbjct: 1141 LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH 1200
Query: 1201 QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL 1260
QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL
Sbjct: 1201 QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL 1260
Query: 1261 RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL 1320
RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL
Sbjct: 1261 RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL 1320
Query: 1321 NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF 1380
NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF
Sbjct: 1321 NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF 1380
Query: 1381 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG 1440
GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG
Sbjct: 1381 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG 1440
Query: 1441 TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG 1500
TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG
Sbjct: 1441 TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG 1500
Query: 1501 SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV 1560
SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV
Sbjct: 1501 SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV 1560
Query: 1561 LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS 1620
LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS
Sbjct: 1561 LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS 1620
Query: 1621 VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT 1680
VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT
Sbjct: 1621 VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT 1680
Query: 1681 TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 1681 TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 3351 bits (8688), Expect = 0.0
Identities = 1668/1668 (100%), Positives = 1668/1668 (100%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN
Sbjct: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 1725
Query: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ
Sbjct: 1726 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 1785
Query: 177 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 236
PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS
Sbjct: 1786 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 1845
Query: 237 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 296
QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL
Sbjct: 1846 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 1905
Query: 297 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 356
QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD
Sbjct: 1906 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 1965
Query: 357 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 416
FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR
Sbjct: 1966 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 2025
Query: 417 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 476
DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT
Sbjct: 2026 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 2085
Query: 477 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 536
TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH
Sbjct: 2086 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 2145
Query: 537 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 596
ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ
Sbjct: 2146 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 2205
Query: 597 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 656
TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN
Sbjct: 2206 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 2265
Query: 657 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 716
LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN
Sbjct: 2266 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 2325
Query: 717 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 776
EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS
Sbjct: 2326 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 2385
Query: 777 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 836
KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS
Sbjct: 2386 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 2445
Query: 837 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 896
RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK
Sbjct: 2446 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 2505
Query: 897 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 956
GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD
Sbjct: 2506 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 2565
Query: 957 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 1016
DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT
Sbjct: 2566 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 2625
Query: 1017 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1076
IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK
Sbjct: 2626 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 2685
Query: 1077 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 1136
IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS
Sbjct: 2686 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 2745
Query: 1137 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 1196
GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI
Sbjct: 2746 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 2805
Query: 1197 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 1256
LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID
Sbjct: 2806 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 2865
Query: 1257 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316
DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG
Sbjct: 2866 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 2925
Query: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 1376
GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG
Sbjct: 2926 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 2985
Query: 1377 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 1436
ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV
Sbjct: 2986 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 3045
Query: 1437 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1496
FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP
Sbjct: 3046 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3105
Query: 1497 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 1556
VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG
Sbjct: 3106 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 3165
Query: 1557 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 1616
GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG
Sbjct: 3166 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 3225
Query: 1617 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 1676
TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP
Sbjct: 3226 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 3285
Query: 1677 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 3286 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3333
Score = 97.4 bits (241), Expect = 1e-19
Identities = 61/199 (30%), Positives = 77/199 (38%), Gaps = 49/199 (24%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
C GY +R + C CNC+GH++ C G G+C+N
Sbjct: 333 CCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCIN 392
Query: 97 CQHNTAGEHCERCQEGY---YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
CQHNTAG +CE+C +GY YG V PC A GC G RC CK +
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSG--RCHCKPNFH 450
Query: 154 GTQCERCAPGYFGNP----------------QKFGGSCQPCSCNSNGQLGSCHPLTGDCI 197
G CE+CA GY+ P G + C CN G L G C+
Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
Query: 198 NQEPKDSSPAEECDDCDSC 216
P E CD+C
Sbjct: 511 ------CRPGVEGPRCDTC 523
Score = 80.9 bits (198), Expect = 1e-14
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 24/176 (13%)
Query: 42 GQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT 101
GQ Q + + R C+ G+Y RC PC+C C++ +G C C T
Sbjct: 1283 GQCPCQPNVIG-RQCTRCATGHYG------FPRCKPCSCG--RRLCEEMTGQC-RCPPRT 1332
Query: 102 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGYTGTQCE 158
CE C+ + C C C + C + G +C CK TG QC+
Sbjct: 1333 VRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG--QCRCKPRITGRQCD 1390
Query: 159 RCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
RCA G++ P+ C PC+CN +G + G C P TG C+ +E + + EC+ C
Sbjct: 1391 RCASGFYRFPE-----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGT---ECNVC 1438
Score = 71.6 bits (174), Expect = 6e-12
Identities = 55/187 (29%), Positives = 72/187 (38%), Gaps = 36/187 (19%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG---ICVNCQHNTAGEHCERCQEGYYGNAVH 119
YY K + G C CNGH+ C + CQH+T GE C+RC GY
Sbjct: 286 YYYSIKDISIGG--QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 120 GS-------CRACPC-PHTN-------------SFATGCVVNGGDVRCSCKAGYTGTQCE 158
+ C AC C H + S T + GG V +C+ G CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 159 RCAPGY---FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
+CA GY +G P C PCSC+ G C +G C P D+C+
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRC------HCKPNFHGDNCEK 456
Query: 216 CVMTLLN 222
C + N
Sbjct: 457 CAIGYYN 463
Score = 64.3 bits (155), Expect = 1e-09
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 9/114 (7%)
Query: 78 CNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC 137
CN G + D G C+ C+ G C+ C+ G+Y + C+AC C S+ C
Sbjct: 493 CNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPC 548
Query: 138 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS--CQPCSCNSNGQLGSC 189
G +C C+ G TG +C+RC G + P G S C P N LG C
Sbjct: 549 SSVTG--QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAG-TINSNLGYC 599
Score = 58.9 bits (141), Expect = 4e-08
Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 8/126 (6%)
Query: 79 NCNGHSNQCQDGSGICVN-----CQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTN 131
+C G S+ C I N C+ + G C RC+ Y+ C C C
Sbjct: 578 HCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
Query: 132 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CH 190
+ + GD C CK+ G C+ C GYF + CQ C C+ G L S C
Sbjct: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
Query: 191 PLTGDC 196
+G C
Sbjct: 698 GPSGVC 703
Score = 56.2 bits (134), Expect = 3e-07
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 14/97 (14%)
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
H C C T + C GG +C C+ G QC RCA G++G P+ C+PC
Sbjct: 1260 HKGALPCECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFPR-----CKPC 1312
Query: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
SC C +TG C P+ P +C+ C++
Sbjct: 1313 SCGRR----LCEEMTGQC-RCPPRTVRP--QCEVCET 1342
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/124 (30%), Positives = 47/124 (37%), Gaps = 15/124 (12%)
Query: 75 CVPCNCNGHSN------QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
C CNC+ +C SG C C+ G C+RC G+Y C C C
Sbjct: 1353 CEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYR---FPECVPCNCN 1408
Query: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSC-NSNGQL 186
+ C + G C CK GT+C C G F +P G C C C N Q
Sbjct: 1409 RDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKG-CTSCFCFGVNNQC 1465
Query: 187 GSCH 190
S H
Sbjct: 1466 HSSH 1469
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C GY+ K Y G C C C+ S+ C SG+C C+ + G+ C+R + YY
Sbjct: 666 CEDGYFALEKSNYFG-CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYYF 723
Query: 116 NAVH 119
+H
Sbjct: 724 PDLH 727
>gi|189217428 laminin alpha 3 subunit isoform 4 [Homo sapiens]
Length = 1668
Score = 3286 bits (8521), Expect = 0.0
Identities = 1653/1724 (95%), Positives = 1658/1724 (96%), Gaps = 56/1724 (3%)
Query: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS
Sbjct: 1 MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS 60
Query: 61 PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG 120
PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG
Sbjct: 61 PGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG 120
Query: 121 SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC
Sbjct: 121 SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
Query: 181 NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG 240
NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG
Sbjct: 181 NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQG 240
Query: 241 LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA 300
LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA
Sbjct: 241 LSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKA 300
Query: 301 QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSRE 360
QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVH+L N + R
Sbjct: 301 QVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHML-----------NRI------RT 343
Query: 361 WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLN 420
W + + E+ L N IR DSLN
Sbjct: 344 WQKTH---------------------QGENNGLANSIR------------------DSLN 364
Query: 421 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 480
EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS
Sbjct: 365 EYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADS 424
Query: 481 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL 540
SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL
Sbjct: 425 SLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL 484
Query: 541 QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK 600
QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK
Sbjct: 485 QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK 544
Query: 601 EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL 660
EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL
Sbjct: 545 EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTL 604
Query: 661 RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK 720
RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK
Sbjct: 605 RDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK 664
Query: 721 KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV 780
KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV
Sbjct: 665 KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAV 724
Query: 781 PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI 840
PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI
Sbjct: 725 PMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYI 784
Query: 841 GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS 900
GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS
Sbjct: 785 GMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS 844
Query: 901 SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE 960
SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE
Sbjct: 845 SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNE 904
Query: 961 NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT 1020
NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT
Sbjct: 905 NVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTT 964
Query: 1021 VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL 1080
VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL
Sbjct: 965 VDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL 1024
Query: 1081 QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR 1140
QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR
Sbjct: 1025 QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVR 1084
Query: 1141 LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH 1200
LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH
Sbjct: 1085 LNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDH 1144
Query: 1201 QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL 1260
QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL
Sbjct: 1145 QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL 1204
Query: 1261 RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL 1320
RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL
Sbjct: 1205 RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSL 1264
Query: 1321 NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF 1380
NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF
Sbjct: 1265 NKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQF 1324
Query: 1381 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG 1440
GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG
Sbjct: 1325 GDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLVFALG 1384
Query: 1441 TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG 1500
TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG
Sbjct: 1385 TDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAPVYLG 1444
Query: 1501 SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV 1560
SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV
Sbjct: 1445 SPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEGGHVV 1504
Query: 1561 LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS 1620
LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS
Sbjct: 1505 LAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTS 1564
Query: 1621 VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT 1680
VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT
Sbjct: 1565 VTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANLT 1624
Query: 1681 TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 1625 TLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1668
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 3170 bits (8218), Expect = 0.0
Identities = 1597/1668 (95%), Positives = 1602/1668 (96%), Gaps = 56/1668 (3%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN
Sbjct: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 1725
Query: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ
Sbjct: 1726 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 1785
Query: 177 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 236
PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS
Sbjct: 1786 PCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKS 1845
Query: 237 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 296
QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL
Sbjct: 1846 QLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 1905
Query: 297 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGD 356
QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVH+L N +
Sbjct: 1906 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHML-----------NRI---- 1950
Query: 357 FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIR 416
R W + + E+ L N IR
Sbjct: 1951 --RTWQKTH---------------------QGENNGLANSIR------------------ 1969
Query: 417 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 476
DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT
Sbjct: 1970 DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLT 2029
Query: 477 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 536
TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH
Sbjct: 2030 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 2089
Query: 537 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 596
ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ
Sbjct: 2090 ARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 2149
Query: 597 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 656
TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN
Sbjct: 2150 TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTN 2209
Query: 657 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 716
LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN
Sbjct: 2210 LTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQN 2269
Query: 717 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 776
EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS
Sbjct: 2270 EDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS 2329
Query: 777 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 836
KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS
Sbjct: 2330 KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDAS 2389
Query: 837 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 896
RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK
Sbjct: 2390 RDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTK 2449
Query: 897 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 956
GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD
Sbjct: 2450 GATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD 2509
Query: 957 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 1016
DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT
Sbjct: 2510 DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQT 2569
Query: 1017 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1076
IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK
Sbjct: 2570 IQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 2629
Query: 1077 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 1136
IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS
Sbjct: 2630 IGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS 2689
Query: 1137 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 1196
GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI
Sbjct: 2690 GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGI 2749
Query: 1197 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 1256
LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID
Sbjct: 2750 LLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLID 2809
Query: 1257 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 1316
DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG
Sbjct: 2810 DQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG 2869
Query: 1317 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 1376
GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG
Sbjct: 2870 GCSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHG 2929
Query: 1377 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 1436
ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV
Sbjct: 2930 ALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKNSFMALYLSKGRLV 2989
Query: 1437 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 1496
FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP
Sbjct: 2990 FALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRAP 3049
Query: 1497 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 1556
VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG
Sbjct: 3050 VYLGSPPSGKPKSLPTNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFSEEG 3109
Query: 1557 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 1616
GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG
Sbjct: 3110 GHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGG 3169
Query: 1617 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 1676
TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP
Sbjct: 3170 TSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAP 3229
Query: 1677 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 1724
ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ
Sbjct: 3230 ANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCPDQ 3277
Score = 97.4 bits (241), Expect = 1e-19
Identities = 61/199 (30%), Positives = 77/199 (38%), Gaps = 49/199 (24%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
C GY +R + C CNC+GH++ C G G+C+N
Sbjct: 333 CCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCIN 392
Query: 97 CQHNTAGEHCERCQEGY---YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
CQHNTAG +CE+C +GY YG V PC A GC G RC CK +
Sbjct: 393 CQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSG--RCHCKPNFH 450
Query: 154 GTQCERCAPGYFGNP----------------QKFGGSCQPCSCNSNGQLGSCHPLTGDCI 197
G CE+CA GY+ P G + C CN G L G C+
Sbjct: 451 GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCL 510
Query: 198 NQEPKDSSPAEECDDCDSC 216
P E CD+C
Sbjct: 511 ------CRPGVEGPRCDTC 523
Score = 80.9 bits (198), Expect = 1e-14
Identities = 53/176 (30%), Positives = 78/176 (44%), Gaps = 24/176 (13%)
Query: 42 GQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT 101
GQ Q + + R C+ G+Y RC PC+C C++ +G C C T
Sbjct: 1283 GQCPCQPNVIG-RQCTRCATGHYG------FPRCKPCSCG--RRLCEEMTGQC-RCPPRT 1332
Query: 102 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATG---CVVNGGDVRCSCKAGYTGTQCE 158
CE C+ + C C C + C + G +C CK TG QC+
Sbjct: 1333 VRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSG--QCRCKPRITGRQCD 1390
Query: 159 RCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
RCA G++ P+ C PC+CN +G + G C P TG C+ +E + + EC+ C
Sbjct: 1391 RCASGFYRFPE-----CVPCNCNRDGTEPGVCDPGTGACLCKENVEGT---ECNVC 1438
Score = 71.6 bits (174), Expect = 6e-12
Identities = 55/187 (29%), Positives = 72/187 (38%), Gaps = 36/187 (19%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG---ICVNCQHNTAGEHCERCQEGYYGNAVH 119
YY K + G C CNGH+ C + CQH+T GE C+RC GY
Sbjct: 286 YYYSIKDISIGG--QCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWR 343
Query: 120 GS-------CRACPC-PHTN-------------SFATGCVVNGGDVRCSCKAGYTGTQCE 158
+ C AC C H + S T + GG V +C+ G CE
Sbjct: 344 PAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCE 403
Query: 159 RCAPGY---FGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
+CA GY +G P C PCSC+ G C +G C P D+C+
Sbjct: 404 QCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG-CEQGSGRC------HCKPNFHGDNCEK 456
Query: 216 CVMTLLN 222
C + N
Sbjct: 457 CAIGYYN 463
Score = 64.3 bits (155), Expect = 1e-09
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 9/114 (7%)
Query: 78 CNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGC 137
CN G + D G C+ C+ G C+ C+ G+Y + C+AC C S+ C
Sbjct: 493 CNLEGVLPEICDAHGRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCSALGSYQMPC 548
Query: 138 VVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS--CQPCSCNSNGQLGSC 189
G +C C+ G TG +C+RC G + P G S C P N LG C
Sbjct: 549 SSVTG--QCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAG-TINSNLGYC 599
Score = 58.9 bits (141), Expect = 4e-08
Identities = 36/126 (28%), Positives = 49/126 (38%), Gaps = 8/126 (6%)
Query: 79 NCNGHSNQCQDGSGICVN-----CQHNTAGEHCERCQEGYYG--NAVHGSCRACPCPHTN 131
+C G S+ C I N C+ + G C RC+ Y+ C C C
Sbjct: 578 HCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAG 637
Query: 132 SFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CH 190
+ + GD C CK+ G C+ C GYF + CQ C C+ G L S C
Sbjct: 638 TVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCS 697
Query: 191 PLTGDC 196
+G C
Sbjct: 698 GPSGVC 703
Score = 56.2 bits (134), Expect = 3e-07
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 14/97 (14%)
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
H C C T + C GG +C C+ G QC RCA G++G P+ C+PC
Sbjct: 1260 HKGALPCECHPTGATGPHCSPEGG--QCPCQPNVIGRQCTRCATGHYGFPR-----CKPC 1312
Query: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
SC C +TG C P+ P +C+ C++
Sbjct: 1313 SCGRR----LCEEMTGQC-RCPPRTVRP--QCEVCET 1342
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/124 (30%), Positives = 47/124 (37%), Gaps = 15/124 (12%)
Query: 75 CVPCNCNGHSN------QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
C CNC+ +C SG C C+ G C+RC G+Y C C C
Sbjct: 1353 CEGCNCSRRGTIEAAMPECDRDSGQC-RCKPRITGRQCDRCASGFYR---FPECVPCNCN 1408
Query: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSC-NSNGQL 186
+ C + G C CK GT+C C G F +P G C C C N Q
Sbjct: 1409 RDGTEPGVC--DPGTGACLCKENVEGTECNVCREGSFHLDPANLKG-CTSCFCFGVNNQC 1465
Query: 187 GSCH 190
S H
Sbjct: 1466 HSSH 1469
Score = 40.8 bits (94), Expect = 0.012
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 5/64 (7%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN---GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C GY+ K Y G C C C+ S+ C SG+C C+ + G+ C+R + YY
Sbjct: 666 CEDGYFALEKSNYFG-CQGCQCDIGGALSSMCSGPSGVC-QCREHVVGKVCQRPENNYYF 723
Query: 116 NAVH 119
+H
Sbjct: 724 PDLH 727
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 826 bits (2134), Expect = 0.0
Identities = 554/1800 (30%), Positives = 887/1800 (49%), Gaps = 149/1800 (8%)
Query: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98
PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
Query: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGCVVNGGDVRCSCKAGYT 153
NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C G VRC C Y
Sbjct: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
Query: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198
G CERCAPGY+GNP G +C+ C C+ N C +TG C N
Sbjct: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
Query: 199 ----------------------QEPKDSSPAEECDD-------CDSCVMTLLNDLATMGE 229
P DS E ++ CD CV L + L
Sbjct: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAAL 282
Query: 230 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289
+ KS + +S+ A + + L+ +L + + +I E + L
Sbjct: 283 SIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
Query: 290 NQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILLKQI 342
+ E L EK SRK Q + N+ ++ + A ++ KI+ + +
Sbjct: 343 LSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY---- 398
Query: 343 SGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNRIRT 399
GE + + + S + AQ+M+ E+R+R + L + EAD E+ LL++ +
Sbjct: 399 ----GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAES 452
Query: 400 WQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQR 459
WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+ ++
Sbjct: 453 WQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEK 511
Query: 460 QVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRE 519
Q + + L+T+ SL + L ++ K + A ++ A+ EL K+
Sbjct: 512 QQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSN 571
Query: 520 LSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKA 579
LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N +
Sbjct: 572 LSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSE 629
Query: 580 AEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNL 639
A + A A + ++ V + + S+ LLN+A+ Q K + A+ +
Sbjct: 630 ANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADT 687
Query: 640 QQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNP 699
+ + +K + T L+ L +RGD + ++ + +AN T EV P
Sbjct: 688 SRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAP 747
Query: 700 IQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISD 759
+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P N+S
Sbjct: 748 MANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVSA 806
Query: 760 NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-E 818
++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R E
Sbjct: 807 SIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPE 866
Query: 819 NGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVM 878
T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A
Sbjct: 867 LTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AYF 924
Query: 879 DRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDF 938
VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P +F
Sbjct: 925 SIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNF 984
Query: 939 KLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNY 993
KLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K + +
Sbjct: 985 KLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYF 1044
Query: 994 FEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY 1049
F+G+GYA V + F ++T D GL+ NG F L + +G L V Y
Sbjct: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
Query: 1050 K---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGEV 1099
L L K + IN+ + H I I I K+M + VD ++ +D E
Sbjct: 1105 DFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEK 1158
Query: 1100 FD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTK 1149
F+ Y+GG P I + + FRGCMK KK ++ +T+GV
Sbjct: 1159 MKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGY 1218
Query: 1150 KCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQ 1208
C ED + R A F+ GQ + + D + F F+T QP+G+L + + +
Sbjct: 1219 GCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFS 1276
Query: 1209 VTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK---- 1264
++L++G + + G + + Y DGL H+V + L++D + +
Sbjct: 1277 ISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKG 1334
Query: 1265 RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGG 1317
+++ +S + GGS NF GCISN + R+ EV D + K SL
Sbjct: 1335 KIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYE 1394
Query: 1318 CSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLP 1369
C + P +L K +K K + + +D P P ++K+ + C
Sbjct: 1395 CPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSN 1454
Query: 1370 KTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFMA 1427
+A A Q+G S F+ + +SQF++ ++T SS G++F+ + N FM
Sbjct: 1455 SPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMT 1514
Query: 1428 LYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPG 1487
L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SLP
Sbjct: 1515 LFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPP 1574
Query: 1488 N-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSCL 1542
+T I+ P+YLG GK K++ NS F GCL N QL+ + + S +F V+ C
Sbjct: 1575 TEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCF 1634
Query: 1543 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1602
GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V+++
Sbjct: 1635 EGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMK 1694
Query: 1603 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1662
G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G +
Sbjct: 1695 NGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPK 1754
Query: 1663 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1722
P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N CP
Sbjct: 1755 PIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
>gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 826 bits (2134), Expect = 0.0
Identities = 554/1800 (30%), Positives = 887/1800 (49%), Gaps = 149/1800 (8%)
Query: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98
PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
Query: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGCVVNGGDVRCSCKAGYT 153
NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C G VRC C Y
Sbjct: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
Query: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ----LGSCHPLTGDCIN----------- 198
G CERCAPGY+GNP G +C+ C C+ N C +TG C N
Sbjct: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
Query: 199 ----------------------QEPKDSSPAEECDD-------CDSCVMTLLNDLATMGE 229
P DS E ++ CD CV L + L
Sbjct: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAAL 282
Query: 230 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289
+ KS + +S+ A + + L+ +L + + +I E + L
Sbjct: 283 SIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
Query: 290 NQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRNVHILLKQI 342
+ E L EK SRK Q + N+ ++ + A ++ KI+ + +
Sbjct: 343 LSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNKMLYY---- 398
Query: 343 SGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQLLLNRIRT 399
GE + + + S + AQ+M+ E+R+R + L + EAD E+ LL++ +
Sbjct: 399 ----GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAYELLSQAES 452
Query: 400 WQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQR 459
WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+ ++
Sbjct: 453 WQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATAARQRDHEK 511
Query: 460 QVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRE 519
Q + + L+T+ SL + L ++ K + A ++ A+ EL K+
Sbjct: 512 QQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKSELQVKLSN 571
Query: 520 LSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKA 579
LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YENI+N +
Sbjct: 572 LSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYENIVNYVSE 629
Query: 580 AEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNL 639
A + A A + ++ V + + S+ LLN+A+ Q K + A+ +
Sbjct: 630 ANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESSSDEAVADT 687
Query: 640 QQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNP 699
+ + +K + T L+ L +RGD + ++ + +AN T EV P
Sbjct: 688 SRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTMEVQQATAP 747
Query: 700 IQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISD 759
+ ++ + + A+ A ++V LT +P L ++ ++ Q+ P N+S
Sbjct: 748 MANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR-PASNVSA 806
Query: 760 NMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSR-E 818
++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL+++ P R E
Sbjct: 807 SIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYMKPPVKRPE 866
Query: 819 NGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVM 878
T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D S A
Sbjct: 867 LTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVSSWP--AYF 924
Query: 879 DRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDF 938
VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFYVGG P +F
Sbjct: 925 SIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFYVGGVPSNF 984
Query: 939 KLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK-----EESDKNY 993
KLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K + +
Sbjct: 985 KLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFTQSRAASYF 1044
Query: 994 FEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRY 1049
F+G+GYA V + F ++T D GL+ NG F L + +G L V Y
Sbjct: 1045 FDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMRNGYLHVFY 1104
Query: 1050 K---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNT-IIDGEV 1099
L L K + IN+ + H I I I K+M + VD ++ +D E
Sbjct: 1105 DFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRHVKSMDNEK 1158
Query: 1100 FD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRLNDTVGVTK 1149
F+ Y+GG P I + + FRGCMK KK ++ +T+GV
Sbjct: 1159 MKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGY 1218
Query: 1150 KCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQ 1208
C ED + R A F+ GQ + + D + F F+T QP+G+L + + +
Sbjct: 1219 GCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYASGSDVFS 1276
Query: 1209 VTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK---- 1264
++L++G + + G + + Y DGL H+V + L++D + +
Sbjct: 1277 ISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRVGSKNPTKG 1334
Query: 1265 RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGG 1317
+++ +S + GGS NF GCISN + R+ EV D + K SL
Sbjct: 1335 KIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTEKVHTSLYE 1394
Query: 1318 CSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ------DACSPLP 1369
C + P +L K +K K + + +D P P ++K+ + C
Sbjct: 1395 CPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPRNSHCHLSN 1454
Query: 1370 KTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTK--NSFMA 1427
+A A Q+G S F+ + +SQF++ ++T SS G++F+ + N FM
Sbjct: 1455 SPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSDQEENDFMT 1514
Query: 1428 LYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPG 1487
L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR E SLP
Sbjct: 1515 LFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLRVLEESLPP 1574
Query: 1488 N-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSSSFGVSSCL 1542
+T I+ P+YLG GK K++ NS F GCL N QL+ + + S +F V+ C
Sbjct: 1575 TEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQTFSVTPCF 1634
Query: 1543 GGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLE 1602
GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G++L V+++
Sbjct: 1635 EGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMK 1694
Query: 1603 AGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP 1662
G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++ G +
Sbjct: 1695 NGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPK 1754
Query: 1663 PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1722
P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G VS+N CP
Sbjct: 1755 PIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSGAVSINSCP 1814
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 825 bits (2130), Expect = 0.0
Identities = 554/1808 (30%), Positives = 890/1808 (49%), Gaps = 158/1808 (8%)
Query: 40 PPGQSQLQASYVEFRPS-QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQ 98
PP S+ + + P+ + C+ G++ +G CVPC+CNG+SN+C DGSG CV+CQ
Sbjct: 47 PPETSEPRVALGRLPPAAEKCNAGFFHT----LSGECVPCDCNGNSNECLDGSGYCVHCQ 102
Query: 99 HNTAGEHCERCQEGYYGNAVHGS---CRACPCP--HTNSFATGCVVNGGDVRCSCKAGYT 153
NT GEHCE+C +GY G+++ G+ C+ CPCP H +FA C G VRC C Y
Sbjct: 103 RNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYA 162
Query: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSN--------------GQL------------- 186
G CERCAPGY+GNP G +C+ C C+ N GQ
Sbjct: 163 GPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCE 222
Query: 187 -----------------------GSCHPLTGDCINQEPKDSSPAEECD--DCDSCVMTLL 221
G C +TG+C+ +E + +C CD CV L
Sbjct: 223 RCAPGYYGDARIAKNCAVCNCGGGPCDSVTGECL-EEGFEPPTGMDCPTISCDKCVWDLT 281
Query: 222 NDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG 281
+ L + KS + +S+ A + + L+ +L + + +I
Sbjct: 282 DALRLAALSIEEGKSGVLSVSSGAAAHRHVNEINATIYLLKTKLSERENQYALRKIQINN 341
Query: 282 LERELTDLNQEFETLQEKAQVNSRKAQTLN-------NNVNRATQSAKELDVKIKNVIRN 334
E + L + E L EK SRK Q + N+ ++ + A ++ KI+ +
Sbjct: 342 AENTMKSLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAHDMRDKIQEINNK 401
Query: 335 VHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRN---FGKHLREAEADKRESQ 391
+ GE + + + S + AQ+M+ E+R+R + L + EAD E+
Sbjct: 402 MLYY--------GEEHELSPKEISEKLVLAQKMLEEIRSRQPFFTQRELVDEEAD--EAY 451
Query: 392 LLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENE 451
LL++ +WQ+ H E L + + L++Y AKLSDL+ L +A + A +N+
Sbjct: 452 ELLSQAESWQRLHN-ETRTLFPVVLEQLDDYNAKLSDLQEALDQALNYVRDAEDMNRATA 510
Query: 452 RALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ 511
++Q + + L+T+ SL + L ++ K + A ++ A+
Sbjct: 511 ARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGIYAEIDGAKS 570
Query: 512 ELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYE 571
EL K+ LS + LV+EA HA+ LQ+ A +L ++ + LV+ A+DA+ YE
Sbjct: 571 ELQVKLSNLSNLSH--DLVQEAIDHAQDLQQEANELSRKLHSSDMNGLVQKALDASNVYE 628
Query: 572 NILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQE 631
NI+N + A + A A + ++ V + + S+ LLN+A+ Q K +
Sbjct: 629 NIVNYVSEANETAEFALNTTDRIYDAV--SGIDTQIIYHKDESENLLNQARELQAKAESS 686
Query: 632 VSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITD 691
A+ + + + +K + T L+ L +RGD + ++ + +AN T
Sbjct: 687 SDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRLITEEANRTTM 746
Query: 692 EVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQL 751
EV P+ ++ + + A+ A ++V LT +P L ++ ++ Q+
Sbjct: 747 EVQQATAPMANNLTNWSQNLQHFDSSAYNTAVNSARDAVRNLTEVVPQLLDQLRTVEQKR 806
Query: 752 LPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFL 811
P N+S ++ RIRELI Q R ASK+ V M F+G+S VEV ++DLK +TSLSL++
Sbjct: 807 -PASNVSASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHSRTSMDDLKAFTSLSLYM 865
Query: 812 QRPNSR-ENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTK 870
+ P R E T + F++YLG+K+A ++Y+G+A+ + L VYNLG ++ E+ +D
Sbjct: 866 KPPVKRPELTETADQFILYLGSKNAKKEYMGLAIKNDNLVYVYNLGTKDVEIPLDSKPVS 925
Query: 871 SETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFY 930
S A VK +R+ + ++ T + SS E + + ++LL+LDPE+ VFY
Sbjct: 926 SWP--AYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFSGDDSLLDLDPEDTVFY 983
Query: 931 VGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRK---- 986
VGG P +FKLP+ L+ P + GC+EL LN +V+SLYNFK +N++ + PC R K
Sbjct: 984 VGGVPSNFKLPTSLNLPGFVGCLELATLNNDVISLYNFKHIYNMDPSTSVPCARDKLAFT 1043
Query: 987 -EESDKNYFEGTGYARVPTQPH----APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIE 1041
+ +F+G+GYA V + F ++T D GL+ NG F L +
Sbjct: 1044 QSRAASYFFDGSGYAVVRDITRRGKFGQVTRFDIEVRTPADNGLILLMVNGSMFFRLEMR 1103
Query: 1042 DGKLMVRYK---------LNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQN 1092
+G L V Y L L K + IN+ + H I I I K+M + VD ++
Sbjct: 1104 NGYLHVFYDFGFSGGPVHLEDTLKKAQ-----INDAKYHEISI-IYHNDKKMILVVDRRH 1157
Query: 1093 T-IIDGEVFD--FSTYYLGGIPIAIRERFNISTPA-----FRGCMKNL---KKTSGVVRL 1141
+D E F+ Y+GG P I + + FRGCMK KK ++
Sbjct: 1158 VKSMDNEKMKIPFTDIYIGGAPPEILQSRALRAHLPLDINFRGCMKGFQFQKKDFNLLEQ 1217
Query: 1142 NDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLG-LPPTDHLQASFGFQTFQPSGILLDH 1200
+T+GV C ED + R A F+ GQ + + D + F F+T QP+G+L +
Sbjct: 1218 TETLGVGYGCPEDSLISRRAYFN--GQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYY 1275
Query: 1201 QTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL 1260
+ + ++L++G + + G + + Y DGL H+V + L++D +
Sbjct: 1276 ASGSDVFSISLDNGTVIMDVK--GIKVQSVDKQYNDGLSHFVISSVSPTRYELIVDKSRV 1333
Query: 1261 RNSK----RLKHISSSRQSLRLGGS-------NFEGCISNVFVQRLSLSPEVLDLTSNSL 1309
+ +++ +S + GGS NF GCISN + R+ EV D +
Sbjct: 1334 GSKNPTKGKIEQTQASEKKFYFGGSPISAQYANFTGCISNAYFTRVDRDVEVEDFQRYTE 1393
Query: 1310 KRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQ--LLQDTPVASPRSVKVWQ----- 1362
K SL C + P +L K +K K + + +D P P ++K+ +
Sbjct: 1394 KVHTSLYECPIESSPLFLLHKKGKNLSKPKASQNKKGGKSKDAPSWDPVALKLPERNTPR 1453
Query: 1363 -DACSPLPKTQANHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGT 1421
C +A A Q+G S F+ + +SQF++ ++T SS G++F+
Sbjct: 1454 NSHCHLSNSPRAIEHAYQYGGTANSRQEFEHLKGDFGAKSQFSIRLRTRSSHGMIFYVSD 1513
Query: 1422 K--NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLR 1479
+ N FM L+L+ GRLV+ KKL+I+S+EK NDG WH V+F + GRLV+DGLR
Sbjct: 1514 QEENDFMTLFLAHGRLVYMFNVGHKKLKIRSQEKYNDGLWHDVIFIRERSSGRLVIDGLR 1573
Query: 1480 AREGSLPGN-STISIRAPVYLGSPPSGKP-KSLPTNS---FVGCLKNFQLDSKPLYTPSS 1534
E SLP +T I+ P+YLG GK K++ NS F GCL N QL+ + + S
Sbjct: 1574 VLEESLPPTEATWKIKGPIYLGGVAPGKAVKNVQINSIYSFSGCLSNLQLNGASITSASQ 1633
Query: 1535 SFGVSSCLGGPLEKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPG 1594
+F V+ C GP+E G YFS EGG+VVL S +G +F++ F +RPRS +G L+H S G
Sbjct: 1634 TFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNG 1693
Query: 1595 KHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSY 1654
++L V+++ G+V +++G STSVTPKQSLCDG+WH + V +++ L++D++ ++
Sbjct: 1694 EYLNVHMKNGQVIVKVNNGIRDFSTSVTPKQSLCDGRWHRITVIRDSNVVQLDVDSEVNH 1753
Query: 1655 TAGQIPFPPASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQG 1714
G + P +EP+ +GG P +L T R+ K F GC+R+ ++ PV ++A V G
Sbjct: 1754 VVGPLNPKPIDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDGHPVSFSKAALVSG 1813
Query: 1715 PVSLNGCP 1722
VS+N CP
Sbjct: 1814 AVSINSCP 1821
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 760 bits (1962), Expect = 0.0
Identities = 553/1730 (31%), Positives = 846/1730 (48%), Gaps = 108/1730 (6%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ-CQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
C+PG+Y + L G C C+C + C SG C+ C+ G C+RCQEG++G
Sbjct: 2006 CAPGFYGN--ALLPGNCTRCDCTPCGTEACDPHSGHCL-CKAGVTGRRCDRCQEGHFGFD 2062
Query: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
G CR C C A G + +C C+ G G QC CAPGY+G P++ C+
Sbjct: 2063 GCGGCRPCAC---GPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLPEQ---GCRR 2116
Query: 178 CSCNSNGQLGSCHPLTGDCI----------------NQEPKDSSPAEE---CDDCDSCVM 218
C C G C P TG C +Q P P C+ CD CV+
Sbjct: 2117 CQCPG----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVV 2172
Query: 219 TLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSK 278
LL+DL G L + QL+G++AS+ ++ + DL++QL + +
Sbjct: 2173 LLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQ 2232
Query: 279 IEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHIL 338
+E LE++ T L Q+ L +A +A L AK L I+ V R + L
Sbjct: 2233 LEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSEL 2292
Query: 339 LKQISGTDGEGNNVPSGD-FSREWAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRI 397
+ Q + PSG+ R AE +R++ E+R R+ G AEA+ +Q LL R+
Sbjct: 2293 MSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARV 2352
Query: 398 RTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAI 457
+ + EN LA RD L ++EA L DLR L A ++A LN N+ L
Sbjct: 2353 QEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEA 2412
Query: 458 QRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKV 517
++ +E++ + L A +L L ++++++E E+LAASL+ AR L ++
Sbjct: 2413 LQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRM 2472
Query: 518 RELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAI 577
+ S + K LVE AE HA+ L +LA L I + + D L + A++A+ AY IL A+
Sbjct: 2473 QTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQRAIEASNAYSRILQAV 2532
Query: 578 KAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALN 637
+AAEDAA +A ++ TV+++ L +A+ L +NS L EA + +++ V AL
Sbjct: 2533 QAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANS-TALEEAMLQEQQRLGLVWAALQ 2591
Query: 638 NLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGL 697
+ L V +K+ ++ ++ + + + + I+ AK++ +A D V L
Sbjct: 2592 GARTQLRDVRAKKDQLEAHIQAAQ-AMLAMDTDETSKKIAHAKAVAAEAQDTATRVQSQL 2650
Query: 698 NPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGN- 756
+Q +VER + Y + +D +A+ DA +SV+ L LP L K+ + + + +
Sbjct: 2651 QAMQENVERWQGQYEGLRGQDLGQAVLDAGHSVSTLEKTLPQLLAKLSILENRGVHNASL 2710
Query: 757 -ISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPN 815
+S ++ R+RELI QAR AASKV VPM+FNG+SGV++R P DL DL YT+L +LQ P
Sbjct: 2711 ALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLAAYTALKFYLQGPE 2770
Query: 816 SRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDR-EAELQVDQILTKSETK 874
GTE+ FVMY+G++ A+ DY+G+++ D ++ VY LG+ A L +D+ + +
Sbjct: 2771 PEPGQGTEDRFVMYMGSRQATGDYMGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQ--- 2827
Query: 875 EAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGY 934
V R QF ++ T + ET G D + LLNL P++ VFYVGGY
Sbjct: 2828 ---FAAVSLDRTLQFGHMSVTVERQMIQ-ETKG--DTVAPGAEGLLNLRPDDFVFYVGGY 2881
Query: 935 PPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEE-----S 989
P F P L FP Y+GCIE+D LNE V+SLYNF++TF L+T PC R K +
Sbjct: 2882 PSTFTPPPLLRFPGYRGCIEMDTLNEEVVSLYNFERTFQLDTAVDRPCARSKSTGDPWLT 2941
Query: 990 DKNYFEGTGYARVPTQPH-APIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVR 1048
D +Y +GTG+AR+ + F Q ++ G+LFF + +F+ L +++G L++
Sbjct: 2942 DGSYLDGTGFARISFDSQISTTKRFEQELRLVSYSGVLFFLKQQSQFLCLAVQEGSLVLL 3001
Query: 1049 YKLNSELPKERGVGDAIN-NGRDHSIQI-KIGKLQKRMWINVD---VQNTIIDGEVFDFS 1103
Y + L K + +IQ+ +G +KR+ + V+ V + D ++
Sbjct: 3002 YDFGAGLKKAVPLQPPPPLTSASKAIQVFLLGGSRKRVLVRVERATVYSVEQDNDLELAD 3061
Query: 1104 TYYLGGI-----PIAIRERFNISTPAFRGCMKNLKKTSGVVRLN--DTVGVTKKCSEDWK 1156
YYLGG+ P ++R F + + RGC+K +K V L +T GV+ C+ D
Sbjct: 3062 AYYLGGVPPDQLPPSLRRLFP-TGGSVRGCVKGIKALGKYVDLKRLNTTGVSAGCTADLL 3120
Query: 1157 LVRSASFSRGGQLSFTDLGLPP-TDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGY 1215
+ R+ +F G L + P T ++ + FGF + Q S +L + QV+L+ G
Sbjct: 3121 VGRAMTFHGHGFLRLALSNVAPLTGNVYSGFGFHSAQDSALLYYRASPDGLCQVSLQQGR 3180
Query: 1216 IELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNS------KRLKHI 1269
+ L + K+ + DG HYV+ S+ +G+ L +DDQL + L+
Sbjct: 3181 VSLQLLRTE---VKTQAGFADGAPHYVAFYSNATGVWLYVDDQLQQMKPHRGPPPELQPQ 3237
Query: 1270 SSSRQSLRLGG-------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNK 1322
L LGG NF GCISNVFVQRL V DL N +VS GC+
Sbjct: 3238 PEGPPRLLLGGLPESGTIYNFSGCISNVFVQRLLGPQRVFDLQQNLGSVNVST-GCA--- 3293
Query: 1323 PPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGD 1382
P G T R P P AC P + + QFG
Sbjct: 3294 PALQAQTPGLGPRGLQATARKASRRSRQPARHP--------ACMLPPHLRTTRDSYQFGG 3345
Query: 1383 IPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTG---TKNSFMALYLSKGRLVFAL 1439
+SHL F + ++ + SSRGL+ T + +AL+LS G V +
Sbjct: 3346 SLSSHLEFVGILARHRNWPSLSMHVLPRSSRGLLLFTARLRPGSPSLALFLSNGHFVAQM 3405
Query: 1440 GTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRA--REGSLPGNSTISIRAPV 1497
G +LR +S+++ G+WH V + + LV DG RA +EG + P
Sbjct: 3406 EGLGTRLRAQSRQRSRPGRWHKVSVRWEKNRILLVTDGARAWSQEGPHRQHQGAEHPQPH 3465
Query: 1498 YL---GSPPSGKPKSLP-TNSFVGCLKNFQLDSKPLYTPSSSFGVSSCLGGPLEKGIYFS 1553
L G P S LP T F GC+K +L +PL P+ GV+ C+ GPLE G++F
Sbjct: 3466 TLFVGGLPASSHSSKLPVTVGFSGCVKRLRLHGRPLGAPTRMAGVTPCILGPLEAGLFFP 3525
Query: 1554 EEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIG-SQPGKHLCVYLEAGKVTASMDS 1612
GG + L P+ L +RP ++TG++ H+G ++ +L + + +V D
Sbjct: 3526 GSGGVITLDLPGATLPDVGLELEVRPLAVTGLIFHLGQARTPPYLQLQVTEKQVLLRADD 3585
Query: 1613 GAGGTSTSVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHL 1672
GAG STSVT LCDGQWH +AV ++L LE+D S++T G + A PL+L
Sbjct: 3586 GAGEFSTSVTRPSVLCDGQWHRLAVMKSGNVLRLEVDAQSNHTVGPLLAAAAGAPAPLYL 3645
Query: 1673 GGAPANLTTLRIPVWKSFFGCLRNIHVNHIPVPVTEALEVQGPVSLNGCP 1722
GG P + P ++ GC+R + VN PV +T ++EV G V +GCP
Sbjct: 3646 GGLPEPMAVQPWP--PAYCGCMRRLAVNRSPVAMTRSVEVHGAVGASGCP 3693
Score = 198 bits (503), Expect = 4e-50
Identities = 85/149 (57%), Positives = 102/149 (68%), Gaps = 9/149 (6%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Q C+PG+YRD KGL+ GRCVPC C+GHS++C GSG+CV+CQHNT G HCERCQ G+ +
Sbjct: 1843 QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCERCQAGFVSS 1902
Query: 117 AVHGS--CRACPCP---HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 171
S C +CPCP +N+FA GCV+ GG +C CK GY G CERCAPG+FGNP
Sbjct: 1903 RDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVL 1962
Query: 172 GGSCQPCSCNSNGQ----LGSCHPLTGDC 196
G SCQPC C+ NG C PLTG C
Sbjct: 1963 GSSCQPCDCSGNGDPNLLFSDCDPLTGAC 1991
Score = 98.2 bits (243), Expect = 6e-20
Identities = 57/162 (35%), Positives = 79/162 (48%), Gaps = 27/162 (16%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
C+PGY+ + C C C+ G + D +G C+ CQ AG HC+RC+ GY+G
Sbjct: 574 CAPGYF------HFPLCQLCGCSPAGTLPEGCDEAGRCL-CQPEFAGPHCDRCRPGYHG- 625
Query: 117 AVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
+C+AC C + C G C C+ GYTGT C+ C+PG+ G P SC
Sbjct: 626 --FPNCQACTCDPRGALDQLCGAGG---LCRCRPGYTGTACQECSPGFHGFP-----SCV 675
Query: 177 PCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECDDCDSCV 217
PC C++ G L +C P +G C P CD+CV
Sbjct: 676 PCHCSAEGSLHAACDPRSGQC------SCRPRVTGLRCDTCV 711
Score = 82.8 bits (203), Expect = 3e-15
Identities = 54/174 (31%), Positives = 72/174 (41%), Gaps = 29/174 (16%)
Query: 59 CSPGYYR--DHKGLYTGRCVPCNCNGH--SNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
C PG+YR +H C CNC C+D +G C C+ N +GE C+ C EG+
Sbjct: 408 CLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFT 466
Query: 115 G-----------NAVH------GSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC 157
G N G C C + C + RC CK + GT C
Sbjct: 467 GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC 526
Query: 158 ERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEEC 210
E CAPG+ +G CQPC C+S G C P TG C + + + + C
Sbjct: 527 ELCAPGF------YGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRC 574
Score = 81.6 bits (200), Expect = 6e-15
Identities = 46/152 (30%), Positives = 66/152 (43%), Gaps = 35/152 (23%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQ------------------DGSGICVN 96
C PG+ ++ C CNC GH+ C G G+C++
Sbjct: 336 CCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCID 395
Query: 97 CQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDVRCSCKAG 151
CQH+T G +CERC G+Y + H CR C C + T + G RC C+
Sbjct: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTG---RCYCRPN 452
Query: 152 YTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN 183
++G +C+ CA G+ G P SC P +SN
Sbjct: 453 FSGERCDVCAEGFTGFP-----SCYPTPSSSN 479
Score = 80.1 bits (196), Expect = 2e-14
Identities = 51/149 (34%), Positives = 68/149 (45%), Gaps = 20/149 (13%)
Query: 70 LYTGRCVPCNCNG---HSNQCQDGS--GICVNCQHNTAGEHCERCQEGYYGNAVHGSCRA 124
L G+ V C+C+ N C+ G C+ C+ N G HCE C G+YG C+
Sbjct: 486 LPAGQIVNCDCSAAGTQGNACRKDPRVGRCL-CKPNFQGTHCELCAPGFYGPG----CQP 540
Query: 125 CPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG 184
C C C + G +C C+ G+ G C+RCAPGYF P CQ C C+ G
Sbjct: 541 CQCSSPGVADDRCDPDTG--QCRCRVGFEGATCDRCAPGYFHFP-----LCQLCGCSPAG 593
Query: 185 QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
L G C+ Q P+ + P CD C
Sbjct: 594 TLPEGCDEAGRCLCQ-PEFAGP--HCDRC 619
Score = 79.3 bits (194), Expect = 3e-14
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 35/170 (20%)
Query: 73 GRCVPCNCNGHSNQCQ-----DGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCR 123
GRCV C+GH++ C D + CQHNT G C+RC G+ + A S
Sbjct: 298 GRCV---CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
Query: 124 ACPCPHTNSFATGC-----------------VVNGGDVRCSCKAGYTGTQCERCAPGYFG 166
C + AT C GG V C+ TG CERC PG++
Sbjct: 355 ECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYR 414
Query: 167 NPQKFGGS---CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
+P S C+ C+C S+ G+C LTG C + + E CD C
Sbjct: 415 SPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCY---CRPNFSGERCDVC 461
Score = 78.2 bits (191), Expect = 7e-14
Identities = 48/162 (29%), Positives = 63/162 (38%), Gaps = 16/162 (9%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSN---QCQDGSGICVNCQHNTAGEHCERCQEGY 113
Q CSPG++ CVPC+C+ + C SG C +C+ G C+ C G
Sbjct: 662 QECSPGFHGFPS------CVPCHCSAEGSLHAACDPRSGQC-SCRPRVTGLRCDTCVPGA 714
Query: 114 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 173
Y C A C + V C C+A G C+RC PG++G
Sbjct: 715 YNFPY---CEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPE 771
Query: 174 SCQPCSCNSNGQLG---SCHPLTGDCINQEPKDSSPAEECDD 212
C CSC+ G LG C P TG C + C D
Sbjct: 772 GCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKD 813
Score = 77.8 bits (190), Expect = 8e-14
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 23/182 (12%)
Query: 36 PFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICV 95
P +P G ++V R C+ GY+ C PC+C + C + +G C+
Sbjct: 1448 PTCEPFGGQCPCHAHVIGRDCSRCATGYWG------FPNCRPCDCG--ARLCDELTGQCI 1499
Query: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPC--PHTNSFATG-CVVNGGDVRCSCKAGY 152
C T C CQ +G C C C P C + G +C C+
Sbjct: 1500 -CPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG--QCKCRPNV 1556
Query: 153 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD 211
TG +C+ C+PG+ G P+ C+PC C+ G G C PLTG C K++ +CD
Sbjct: 1557 TGRRCDTCSPGFHGYPR-----CRPCDCHEAGTAPGVCDPLTGQCY---CKENVQGPKCD 1608
Query: 212 DC 213
C
Sbjct: 1609 QC 1610
Score = 69.3 bits (168), Expect = 3e-11
Identities = 46/158 (29%), Positives = 62/158 (39%), Gaps = 9/158 (5%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
C PG Y + G C P + C+ C+ + G C+RC+ G++G +
Sbjct: 710 CVPGAY-NFPYCEAGSCHPAGLAPVDPALPEAQVPCM-CRAHVEGPSCDRCKPGFWGLSP 767
Query: 119 HG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQ 176
C C C + G +C CK G C C G+FG Q C+
Sbjct: 768 SNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCR 827
Query: 177 PCSCNSNGQLG-SCHPLTGDC----INQEPKDSSPAEE 209
C C+ G LG SC P TG C Q P S PA +
Sbjct: 828 SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
Score = 61.2 bits (147), Expect = 8e-09
Identities = 34/112 (30%), Positives = 46/112 (41%), Gaps = 12/112 (10%)
Query: 75 CVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
C CNC+G Q C SG C C+ N G C+ C G++G + CR C C
Sbjct: 1525 CEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHG---YPRCRPCDCH 1580
Query: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC 180
+ C G +C CK G +C++C+ G F C C C
Sbjct: 1581 EAGTAPGVCDPLTG--QCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 53.5 bits (127), Expect = 2e-06
Identities = 28/79 (35%), Positives = 35/79 (44%), Gaps = 11/79 (13%)
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
+ R C C + C GG +C C A G C RCA GY+G P +C+PC
Sbjct: 1432 NNGARPCGCHEVGATGPTCEPFGG--QCPCHAHVIGRDCSRCATGYWGFP-----NCRPC 1484
Query: 179 SCNSNGQLGSCHPLTGDCI 197
C + C LTG CI
Sbjct: 1485 DCGAR----LCDELTGQCI 1499
Score = 49.7 bits (117), Expect = 2e-05
Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
Query: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCIN-QEPKD 203
C C A Y G C+ CAPG++ + + F G C PC C +G C P +G C++ Q +
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQC--HGHSDRCLPGSGVCVDCQHNTE 1888
Query: 204 SSPAEEC 210
+ E C
Sbjct: 1889 GAHCERC 1895
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 431 bits (1107), Expect = e-120
Identities = 459/1804 (25%), Positives = 755/1804 (41%), Gaps = 217/1804 (12%)
Query: 57 QGCSPGYYRDHK-------GLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC 109
+ C PG+YR G G CVPC CNGHS+ C + IC NCQH+TAG+ CERC
Sbjct: 1392 EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERC 1451
Query: 110 QEGYYG--NAVHGSCRACPCP---HTNSFATGCVVNG-GDVRC-SCKAGYTGTQCERCAP 162
GYYG + C+ C CP +N+F+ CV G D RC +C GY G CERCAP
Sbjct: 1452 ALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAP 1511
Query: 163 GYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC-------- 213
GY G+P GGSCQ C C+ G L C P+TG C + + +CD C
Sbjct: 1512 GYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC---TCRPGATGRKCDGCKHWHAREG 1568
Query: 214 -------DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLL 266
D C LL DLA + EQ+ + + L A +L + +M + K LL
Sbjct: 1569 WECVFCGDECTGLLLGDLARL-EQMVMSINLTGPLPAPYKMLYGLENMTQELK----HLL 1623
Query: 267 NYRSAISNHGSKIEG-LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELD 325
+ + A EG L +T++N E L +V + QT + R AK L
Sbjct: 1624 SPQRAPERLIQLAEGNLNTLVTEMN---ELLTRATKVTADGEQT-GQDAERTNTRAKSLG 1679
Query: 326 VKIKNVIRNVHILLK---QISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLRE 382
IK + R+ + + +++ T G + + E +M++ELR +N
Sbjct: 1680 EFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEI 1739
Query: 383 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQ 442
AE + ++ LL +++ +GEN + +R+ L +Y+ K+ D L+EA + ++
Sbjct: 1740 AEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIRE 1799
Query: 443 ANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKL 502
AN L N++ + A++++ + + S + L + L + N + E +
Sbjct: 1800 ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDI 1859
Query: 503 AASLNEARQELSDKVRELSRSAGKTSLVE---EAEKHARSLQELAKQLEEIKRNASGDEL 559
L +EL+DK+ +LS+ L E +AE HA L + + L+ I A +
Sbjct: 1860 QTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAK--NI 1917
Query: 560 VRCAVDAATAYENILNAIKAAEDAANRAASASESA--LQTVIKEDLPRKAKTLSSNSDKL 617
A A AY NI + I AE A A + A L T + L AK S ++
Sbjct: 1918 SFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRI 1977
Query: 618 LNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQR--GDIDAM 675
LNEAK +K E LN L+ + + + L TL D L + D A
Sbjct: 1978 LNEAKKLANDVK-ENEDHLNGLKTRIENADARNGDL---LRTLNDTLGKLSAIPNDTAAK 2033
Query: 676 ISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK-----------KALT 724
+ + K R+AND +VL + + +++ +K Y + + K K +
Sbjct: 2034 LQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIA 2093
Query: 725 DADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRF 784
DAD +V L + L K++ I + N+ N+ I+ELI QAR A+ + V +
Sbjct: 2094 DADATVKNLEQEADRLIDKLKPIKEL---EDNLKKNISEIKELINQARKQANSIKVSV-- 2148
Query: 785 NGKSGVEVRLPNDLEDLKG-YTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMA 843
SG + E KG Y ++ + ++ + + YLG+ D++ +
Sbjct: 2149 --SSGGDCIRTYKPEIKKGSYNNIVVNVKT-------AVADNLLFYLGSAKFI-DFLAIE 2198
Query: 844 VVDGQLTCVYNLGDREAELQV-DQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSK 902
+ G+++ ++++G ++ D + S V R L+ K +
Sbjct: 2199 MRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASI--- 2255
Query: 903 PETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENV 962
P + T+L++D N + +VGG K + + GC+ +
Sbjct: 2256 --VPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKP 2312
Query: 963 LSLYNFK-KTFNLNTTEVEPCRRRKEESDKN-YFEGTGYARV--PTQPHAPIPTFGQTIQ 1018
+ L+NF+ K + V P + E+S+ F+G GYA V P + + I T +
Sbjct: 2313 IGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEGYALVSRPIRWYPNISTVMFKFR 2369
Query: 1019 TTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1076
T LL + D F+S+ + DG + V Y L S G+ ++N + + K
Sbjct: 2370 TFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS------GMASVVSNQNHNDGKWK 2423
Query: 1077 ---IGKLQKRMWIN-VDVQN-------TIIDGEVFDF-----STYYLGGIPIAIRERFNI 1120
+ ++QK+ I+ VD+ T G F Y GG+P R +
Sbjct: 2424 SFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLRPEV 2483
Query: 1121 STPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLP 1177
+ + GC+K++ + ++ D VGVTK CS + V + SF + G F +L
Sbjct: 2484 NLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCS--LENVYTVSFPKPG---FVELSPV 2538
Query: 1178 PTD-HLQASFGFQTFQPSGILL-------------DHQTWTRNLQVTLEDGYIELSTSDS 1223
P D + + F T SGI+L QT + L G +E+ S
Sbjct: 2539 PIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVHLSTG 2598
Query: 1224 GSPIFK-----SPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSR----Q 1274
+ K P + DG H V V + +D+ N + +++++ + +
Sbjct: 2599 ARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDE----NRRYMQNLTVEQPIEVK 2654
Query: 1275 SLRLGGS-------------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLN 1321
L +GG+ FEGCI N+ + + +D ++ +G C+
Sbjct: 2655 KLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVP-----MDFARPVSFKNADIGRCAHQ 2709
Query: 1322 KPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPR----SVKVWQDACSPLPKTQANHGA 1377
K R ++ ++Q PV +P + + C+ + G+
Sbjct: 2710 K----------LREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPALLIGS 2759
Query: 1378 LQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKN--SFMALYLSKGRL 1435
QFG SH+ +K R ++++T + GL+F+ N F + L G
Sbjct: 2760 KQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLRNGLP 2819
Query: 1436 VFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTISIRA 1495
F+ K NDG+WH + ++G L VDG R S + +
Sbjct: 2820 YFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADILDVVG 2879
Query: 1496 PVYLGSPP---SGKPKSLPTNSFVGCLKNFQLDSKP--LYTPSSSFGVSSCLGGPLEKGI 1550
+Y+G P + + T S GC++N + P L P+SSF V +C ++G
Sbjct: 2880 MLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-AQRGT 2938
Query: 1551 YFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASM 1610
YF + G +G + + F R + TG+L+ I SQ + + + K+ +
Sbjct: 2939 YF-DGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKLMFHV 2997
Query: 1611 DSGAGGTST--SVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP---PAS 1665
D+GAG + LCDGQWH V +H +EL D + Q P P A
Sbjct: 2998 DNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKH--RIELTVDGNQVEAQSPNPASTSAD 3055
Query: 1666 TQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNH-----IPVPVTEALEVQG--PVSL 1718
T +P+ +GG P +L + F GC+R++ + + V +ALE++G PVS
Sbjct: 3056 TNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQPVS- 3114
Query: 1719 NGCP 1722
CP
Sbjct: 3115 --CP 3116
Score = 139 bits (349), Expect = 3e-32
Identities = 66/168 (39%), Positives = 94/168 (55%), Gaps = 13/168 (7%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
+ C P + R + ++ G C PC C GH+ C D +G C+NC+ +T G +C++C G+YG
Sbjct: 736 ESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGE 795
Query: 117 AVHGS---CRACPCP---HTNSFATGCVVNG--GDVRCSCKAGYTGTQCERCAPGYFGNP 168
G+ C+ C CP +N+F+ C ++ G + C GYTG +CERCA GYFG P
Sbjct: 796 PTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP 855
Query: 169 QKFGGSCQPCSCNSNGQL---GSCHPLTGDCINQEPKDSSPAEECDDC 213
GGSCQPC CN N GSC L+G C+ +P + C+ C
Sbjct: 856 SVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP--GTTGRYCELC 901
Score = 96.7 bits (239), Expect = 2e-19
Identities = 54/161 (33%), Positives = 77/161 (47%), Gaps = 14/161 (8%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQEGY 113
C+ GY+ + G C PC CN + + C SG C+ C+ T G +CE C +GY
Sbjct: 847 CAEGYF-GQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGY 905
Query: 114 YGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
+G+AV +C+ C C SF+ C G +C C+A G +C++C G FG G
Sbjct: 906 FGDAVDAKNCQPCRCNAGGSFSEVCHSQTG--QCECRANVQGQRCDKCKAGTFGLQSARG 963
Query: 173 GSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
C PC+CNS G +G C Q ++CD C
Sbjct: 964 --CVPCNCNSFGSKSFDCEESGQCWCQ---PGVTGKKCDRC 999
Score = 91.7 bits (226), Expect = 6e-18
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 17/158 (10%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNG---HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C+ GY+ D + C PC CN S C +G C C+ N G+ C++C+ G +G
Sbjct: 901 CADGYFGD--AVDAKNCQPCRCNAGGSFSEVCHSQTGQC-ECRANVQGQRCDKCKAGTFG 957
Query: 116 NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSC 175
C C C S + C +G +C C+ G TG +C+RCA GYF + G C
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDCEESG---QCWCQPGVTGKKCDRCAHGYFNFQE---GGC 1011
Query: 176 QPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
C C+ G +C P TG CI ++ E+C C
Sbjct: 1012 TACECSHLG--NNCDPKTGRCI---CPPNTIGEKCSKC 1044
Score = 90.5 bits (223), Expect = 1e-17
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 43/199 (21%)
Query: 59 CSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQD------------------GSGICVN 96
C PG++ R L C CNC+G + +C G G+C+N
Sbjct: 321 CCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN 380
Query: 97 CQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGGDVR------ 145
C NTAG +CE C +G++ C+ C C S CV + R
Sbjct: 381 CTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPG 440
Query: 146 -CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C CK G+ G C+RCA GY G P C+ C+C+ G P G CI +E +
Sbjct: 441 SCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-DPCFGPCICKENVEG 494
Query: 205 SPAEECDDCDSCVMTLLND 223
+C C S L D
Sbjct: 495 G---DCSRCKSGFFNLQED 510
Score = 84.7 bits (208), Expect = 7e-16
Identities = 47/160 (29%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
C+ GY+ +G C C C+ N C +G C+ C NT GE C +C +G+++
Sbjct: 999 CAHGYFNFQEG----GCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSI 1053
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ-----KFGG 173
C+AC C S C VN G +C+C ++G +C C+ G++ P+ F
Sbjct: 1054 TTGCKACNCSTVGSLDFQCNVNTG--QCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLP 1111
Query: 174 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
+C+S + SC TG C K + CD C
Sbjct: 1112 GTDATTCDSETKKCSCSDQTGQC---TCKVNVEGIHCDRC 1148
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/180 (26%), Positives = 62/180 (34%), Gaps = 54/180 (30%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQ----DGSGICVNCQHNTAGEHCERCQEGYYGN-- 116
YY K + G C C GH+ C C C+HNT G+ C++C G++
Sbjct: 274 YYYSVKDISVGGM--CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPW 330
Query: 117 -----AVHGSCRACPCPHTNSFATGCVVN-----------------GGDVRCSCKAGYTG 154
C AC C + A C + GG V +C G
Sbjct: 331 RAGTFLTKTECEACNC---HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 155 TQCERCAPGYF---GNPQKFGGSCQPCSCNSNGQL-----------------GSCHPLTG 194
CE C G+F G + CQPC C+ G L GSCH TG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG 447
Score = 60.1 bits (144), Expect = 2e-08
Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 146 CSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C C GYTG+ CE C P + N FGG C+PC C G SC +TG+C+N KD
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAESCDDVTGECLN--CKDH 779
Query: 205 SPAEECDDC 213
+ CD C
Sbjct: 780 TGGPYCDKC 788
Score = 51.6 bits (122), Expect = 7e-06
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 145 RCSCKAGYTGTQCERCAPGYF--------GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC 196
+C C GY+G CE C PG++ P G+C PC CN + L C P T C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSIC 1436
Query: 197 IN-QEPKDSSPAEEC------------DDCDSCVMTLLN 222
N Q E C +DC C L++
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 430 bits (1105), Expect = e-120
Identities = 459/1808 (25%), Positives = 759/1808 (41%), Gaps = 221/1808 (12%)
Query: 57 QGCSPGYYRDHK-------GLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERC 109
+ C PG+YR G G CVPC CNGHS+ C + IC NCQH+TAG+ CERC
Sbjct: 1392 EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCERC 1451
Query: 110 QEGYYG--NAVHGSCRACPCP---HTNSFATGCVVNG-GDVRC-SCKAGYTGTQCERCAP 162
GYYG + C+ C CP +N+F+ CV G D RC +C GY G CERCAP
Sbjct: 1452 ALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAP 1511
Query: 163 GYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC-------- 213
GY G+P GGSCQ C C+ G L C P+TG C + + +CD C
Sbjct: 1512 GYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC---TCRPGATGRKCDGCKHWHAREG 1568
Query: 214 -------DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLL 266
D C LL DLA + EQ+ + + L A +L + +M + K LL
Sbjct: 1569 WECVFCGDECTGLLLGDLARL-EQMVMSINLTGPLPAPYKMLYGLENMTQELK----HLL 1623
Query: 267 NYRSAISNHGSKIEG-LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELD 325
+ + A EG L +T++N E L +V + QT + R AK L
Sbjct: 1624 SPQRAPERLIQLAEGNLNTLVTEMN---ELLTRATKVTADGEQT-GQDAERTNTRAKSLG 1679
Query: 326 VKIKNVIRNVHILLK---QISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLRE 382
IK + R+ + + +++ T G + + E +M++ELR +N
Sbjct: 1680 EFIKELARDAEAVNEKAIKLNETLGTRDEAFERNLEGLQKEIDQMIKELRRKNLETQKEI 1739
Query: 383 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQ 442
AE + ++ LL +++ +GEN + +R+ L +Y+ K+ D L+EA + ++
Sbjct: 1740 AEDELVAAEALLKKVKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIRE 1799
Query: 443 ANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKL 502
AN L N++ + A++++ + + S + L + L + N + E +
Sbjct: 1800 ANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDI 1859
Query: 503 AASLNEARQELSDKVRELSRSAGKTSLVE---EAEKHARSLQELAKQLEEIKRNASGDEL 559
L +EL+DK+ +LS+ L E +AE HA L + + L+ I A +
Sbjct: 1860 QTKLPPMSEELNDKIDDLSQEIKDRKLAEKVSQAESHAAQLNDSSAVLDGILDEAK--NI 1917
Query: 560 VRCAVDAATAYENILNAIKAAEDAANRAASASESA--LQTVIKEDLPRKAKTLSSNSDKL 617
A A AY NI + I AE A A + A L T + L AK S ++
Sbjct: 1918 SFNATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDAKGCLQKSFRI 1977
Query: 618 LNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQR--GDIDAM 675
LNEAK +K E LN L+ + + + L TL D L + D A
Sbjct: 1978 LNEAKKLANDVK-ENEDHLNGLKTRIENADARNGDL---LRTLNDTLGKLSAIPNDTAAK 2033
Query: 676 ISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK-----------KALT 724
+ + K R+AND +VL + + +++ +K Y + + K K +
Sbjct: 2034 LQAVKDKARQANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIA 2093
Query: 725 DADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRF 784
DAD +V L + L K++ I + N+ N+ I+ELI QAR A+ + V +
Sbjct: 2094 DADATVKNLEQEADRLIDKLKPIKEL---EDNLKKNISEIKELINQARKQANSIKVSV-- 2148
Query: 785 NGKSGVEVRLPNDLEDLKG-YTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMA 843
SG + E KG Y ++ + ++ + + YLG+ D++ +
Sbjct: 2149 --SSGGDCIRTYKPEIKKGSYNNIVVNVKT-------AVADNLLFYLGSAKFI-DFLAIE 2198
Query: 844 VVDGQLTCVYNLGDREAELQV-DQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSK 902
+ G+++ ++++G ++ D + S V R L+ K +
Sbjct: 2199 MRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIVASRTGRNGTISVRALDGPKASI--- 2255
Query: 903 PETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENV 962
P + T+L++D N + +VGG K + + GC+ +
Sbjct: 2256 --VPSTHHSTSPPGYTILDVD-ANAMLFVGGLTGKLKKADAVRVITFTGCMGETYFDNKP 2312
Query: 963 LSLYNFK-KTFNLNTTEVEPCRRRKEESDKN-YFEGTGYARV--PTQPHAPIPTFGQTIQ 1018
+ L+NF+ K + V P + E+S+ F+G GYA V P + + I T +
Sbjct: 2313 IGLWNFREKEGDCKGCTVSP---QVEDSEGTIQFDGEGYALVSRPIRWYPNISTVMFKFR 2369
Query: 1019 TTVDRGLLFFAENGD--RFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIK 1076
T LL + D F+S+ + DG + V Y L S G+ ++N + + K
Sbjct: 2370 TFSSSALLMYLATRDLRDFMSVELTDGHIKVSYDLGS------GMASVVSNQNHNDGKWK 2423
Query: 1077 ---IGKLQKRMWIN-VDVQN-------TIIDGEVFDF-----STYYLGGIP----IAIRE 1116
+ ++QK+ I+ VD+ T G F Y GG+P ++++
Sbjct: 2424 SFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLSMKA 2483
Query: 1117 RFNISTPAFRGCMKNL---KKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTD 1173
R ++ + GC+K++ + ++ D VGVTK CS + V + SF + G F +
Sbjct: 2484 RPEVNLKKYSGCLKDIEISRTPYNILSSPDYVGVTKGCS--LENVYTVSFPKPG---FVE 2538
Query: 1174 LGLPPTD-HLQASFGFQTFQPSGILL-------------DHQTWTRNLQVTLEDGYIELS 1219
L P D + + F T SGI+L QT + L G +E+
Sbjct: 2539 LSPVPIDVGTEINLSFSTKNESGIILLGSGGTPAPPRRKRRQTGQAYYVILLNRGRLEVH 2598
Query: 1220 TSDSGSPIFK-----SPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSR- 1273
S + K P + DG H V V + +D+ N + +++++ +
Sbjct: 2599 LSTGARTMRKIVIRPEPNLFHDGREHSVHVERTRGIFTVQVDE----NRRYMQNLTVEQP 2654
Query: 1274 ---QSLRLGGS-------------NFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGG 1317
+ L +GG+ FEGCI N+ + + +D ++ +G
Sbjct: 2655 IEVKKLFVGGAPPEFQPSPLRNIPPFEGCIWNLVINSVP-----MDFARPVSFKNADIGR 2709
Query: 1318 CSLNKPPFLMLLKGSTRFNKTKTFRINQLLQDTPVASPR----SVKVWQDACSPLPKTQA 1373
C+ K R ++ ++Q PV +P + + C+ +
Sbjct: 2710 CAHQK----------LREDEDGAAPAEIVIQPEPVPTPAFPTPTPVLTHGPCAAESEPAL 2759
Query: 1374 NHGALQFGDIPTSHLLFKLPQELLKPRSQFAVDMQTTSSRGLVFHTGTKN--SFMALYLS 1431
G+ QFG SH+ +K R ++++T + GL+F+ N F + L
Sbjct: 2760 LIGSKQFGLSRNSHIAIAFDDTKVKNRLTIELEVRTEAESGLLFYMARINHADFATVQLR 2819
Query: 1432 KGRLVFALGTDGKKLRIKSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNSTI 1491
G F+ K NDG+WH + ++G L VDG R S +
Sbjct: 2820 NGLPYFSYDLGSGDTHTMIPTKINDGQWHKIKIMRSKQEGILYVDGASNRTISPKKADIL 2879
Query: 1492 SIRAPVYLGSPP---SGKPKSLPTNSFVGCLKNFQLDSKP--LYTPSSSFGVSSCLGGPL 1546
+ +Y+G P + + T S GC++N + P L P+SSF V +C
Sbjct: 2880 DVVGMLYVGGLPINYTTRRIGPVTYSIDGCVRNLHMAEAPADLEQPTSSFHVGTCFAN-A 2938
Query: 1547 EKGIYFSEEGGHVVLAHSVLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKV 1606
++G YF + G +G + + F R + TG+L+ I SQ + + + K+
Sbjct: 2939 QRGTYF-DGTGFAKAVGGFKVGLDLLVEFEFRTTTTTGVLLGISSQKMDGMGIEMIDEKL 2997
Query: 1607 TASMDSGAGGTST--SVTPKQSLCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFP-- 1662
+D+GAG + LCDGQWH V +H +EL D + Q P P
Sbjct: 2998 MFHVDNGAGRFTAVYDAGVPGHLCDGQWHKVTANKIKH--RIELTVDGNQVEAQSPNPAS 3055
Query: 1663 -PASTQEPLHLGGAPANLTTLRIPVWKSFFGCLRNIHVNH-----IPVPVTEALEVQG-- 1714
A T +P+ +GG P +L + F GC+R++ + + V +ALE++G
Sbjct: 3056 TSADTNDPVFVGGFPDDLKQFGLTTSIPFRGCIRSLKLTKGTGKPLEVNFAKALELRGVQ 3115
Query: 1715 PVSLNGCP 1722
PVS CP
Sbjct: 3116 PVS---CP 3120
Score = 139 bits (349), Expect = 3e-32
Identities = 66/168 (39%), Positives = 94/168 (55%), Gaps = 13/168 (7%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
+ C P + R + ++ G C PC C GH+ C D +G C+NC+ +T G +C++C G+YG
Sbjct: 736 ESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCDKCLPGFYGE 795
Query: 117 AVHGS---CRACPCP---HTNSFATGCVVNG--GDVRCSCKAGYTGTQCERCAPGYFGNP 168
G+ C+ C CP +N+F+ C ++ G + C GYTG +CERCA GYFG P
Sbjct: 796 PTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQP 855
Query: 169 QKFGGSCQPCSCNSNGQL---GSCHPLTGDCINQEPKDSSPAEECDDC 213
GGSCQPC CN N GSC L+G C+ +P + C+ C
Sbjct: 856 SVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKP--GTTGRYCELC 901
Score = 96.7 bits (239), Expect = 2e-19
Identities = 54/161 (33%), Positives = 77/161 (47%), Gaps = 14/161 (8%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQEGY 113
C+ GY+ + G C PC CN + + C SG C+ C+ T G +CE C +GY
Sbjct: 847 CAEGYF-GQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGY 905
Query: 114 YGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
+G+AV +C+ C C SF+ C G +C C+A G +C++C G FG G
Sbjct: 906 FGDAVDAKNCQPCRCNAGGSFSEVCHSQTG--QCECRANVQGQRCDKCKAGTFGLQSARG 963
Query: 173 GSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
C PC+CNS G +G C Q ++CD C
Sbjct: 964 --CVPCNCNSFGSKSFDCEESGQCWCQ---PGVTGKKCDRC 999
Score = 91.7 bits (226), Expect = 6e-18
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 17/158 (10%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNG---HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C+ GY+ D + C PC CN S C +G C C+ N G+ C++C+ G +G
Sbjct: 901 CADGYFGD--AVDAKNCQPCRCNAGGSFSEVCHSQTGQC-ECRANVQGQRCDKCKAGTFG 957
Query: 116 NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSC 175
C C C S + C +G +C C+ G TG +C+RCA GYF + G C
Sbjct: 958 LQSARGCVPCNCNSFGSKSFDCEESG---QCWCQPGVTGKKCDRCAHGYFNFQE---GGC 1011
Query: 176 QPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
C C+ G +C P TG CI ++ E+C C
Sbjct: 1012 TACECSHLG--NNCDPKTGRCI---CPPNTIGEKCSKC 1044
Score = 90.5 bits (223), Expect = 1e-17
Identities = 58/199 (29%), Positives = 79/199 (39%), Gaps = 43/199 (21%)
Query: 59 CSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQD------------------GSGICVN 96
C PG++ R L C CNC+G + +C G G+C+N
Sbjct: 321 CCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCIN 380
Query: 97 CQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGGDVR------ 145
C NTAG +CE C +G++ C+ C C S CV + R
Sbjct: 381 CTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPG 440
Query: 146 -CSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C CK G+ G C+RCA GY G P C+ C+C+ G P G CI +E +
Sbjct: 441 SCHCKTGFGGVSCDRCARGYTGYP-----DCKACNCSGLGSKNE-DPCFGPCICKENVEG 494
Query: 205 SPAEECDDCDSCVMTLLND 223
+C C S L D
Sbjct: 495 G---DCSRCKSGFFNLQED 510
Score = 84.7 bits (208), Expect = 7e-16
Identities = 47/160 (29%), Positives = 72/160 (45%), Gaps = 15/160 (9%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
C+ GY+ +G C C C+ N C +G C+ C NT GE C +C +G+++
Sbjct: 999 CAHGYFNFQEG----GCTACECSHLGNNCDPKTGRCI-CPPNTIGEKCSKCAPNTWGHSI 1053
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQ-----KFGG 173
C+AC C S C VN G +C+C ++G +C C+ G++ P+ F
Sbjct: 1054 TTGCKACNCSTVGSLDFQCNVNTG--QCNCHPKFSGAKCTECSRGHWNYPRCNLCDCFLP 1111
Query: 174 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
+C+S + SC TG C K + CD C
Sbjct: 1112 GTDATTCDSETKKCSCSDQTGQC---TCKVNVEGIHCDRC 1148
Score = 60.1 bits (144), Expect = 2e-08
Identities = 48/180 (26%), Positives = 62/180 (34%), Gaps = 54/180 (30%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQ----DGSGICVNCQHNTAGEHCERCQEGYYGN-- 116
YY K + G C C GH+ C C C+HNT G+ C++C G++
Sbjct: 274 YYYSVKDISVGGM--CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPW 330
Query: 117 -----AVHGSCRACPCPHTNSFATGCVVN-----------------GGDVRCSCKAGYTG 154
C AC C + A C + GG V +C G
Sbjct: 331 RAGTFLTKTECEACNC---HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 155 TQCERCAPGYF---GNPQKFGGSCQPCSCNSNGQL-----------------GSCHPLTG 194
CE C G+F G + CQPC C+ G L GSCH TG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG 447
Score = 60.1 bits (144), Expect = 2e-08
Identities = 30/69 (43%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 146 CSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C C GYTG+ CE C P + N FGG C+PC C G SC +TG+C+N KD
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQC--FGHAESCDDVTGECLN--CKDH 779
Query: 205 SPAEECDDC 213
+ CD C
Sbjct: 780 TGGPYCDKC 788
Score = 51.6 bits (122), Expect = 7e-06
Identities = 30/99 (30%), Positives = 39/99 (39%), Gaps = 23/99 (23%)
Query: 145 RCSCKAGYTGTQCERCAPGYF--------GNPQKFGGSCQPCSCNSNGQLGSCHPLTGDC 196
+C C GY+G CE C PG++ P G+C PC CN + L C P T C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL--CDPETSIC 1436
Query: 197 IN-QEPKDSSPAEEC------------DDCDSCVMTLLN 222
N Q E C +DC C L++
Sbjct: 1437 QNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLIS 1475
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 405 bits (1040), Expect = e-112
Identities = 445/1787 (24%), Positives = 753/1787 (42%), Gaps = 210/1787 (11%)
Query: 57 QGCSPGYYRDHKGLYTGR--------CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCER 108
Q C+PGY+R + R CVPC+CN HS+ C +G C+NC NTAG+HC+
Sbjct: 1374 QDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDV 1433
Query: 109 CQEGYYGNAVHGS--CRACPCPHTN--SFATGCVVNGG-DVRC-SCKAGYTGTQCERCAP 162
C GYYG + C C CPH+ SF+ CV+ G D RC +C GY G CERC+
Sbjct: 1434 CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSS 1493
Query: 163 GYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDCINQEPKDSSPAEECD--------DC 213
Y+GNPQ GGSCQ C CN +G + G C +G C+ + +EC+ DC
Sbjct: 1494 SYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHILMETDC 1553
Query: 214 ----DSCVMTLLNDLATMGEQLRLVKSQLQGL-SASAGLLEQMRHMETQAKDLRNQLLNY 268
D CV LLNDL +G+ + + L G+ G+L ++E K L+ LL
Sbjct: 1554 VSCDDECVGVLLNDLDEIGDAV--LSLNLTGIIPVPYGILS---NLENTTKYLQESLLKE 1608
Query: 269 RSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKI 328
K+EG+ +E + LQ+K Q +N R + +++L + I
Sbjct: 1609 NMQKDLGKIKLEGVA-------EETDNLQKKLTRMLASTQKVNRATERIFKESQDLAIAI 1661
Query: 329 KNVIRNVHILLKQ--ISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEAD 386
+ + ++ ++++ ++ T E +P+ ++ ++ R+F + + A +
Sbjct: 1662 ERLQMSITEIMEKTTLNQTLDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLHQNATLE 1721
Query: 387 KRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGL 446
+ ++ LL++I+ + E L + L+++ +L A ++EA A+ +++N L
Sbjct: 1722 LKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEAKMQESNHL 1781
Query: 447 N---QENERALGAIQRQVKEINSLQSDF-TKYLTTADSSLLQTNIALQLMEKSQKEYEKL 502
N R + V+E +L S+ + D++ QT+ +E + +KL
Sbjct: 1782 LLMVNANLREFSDKKLHVQEEQNLTSELIVQGRGLIDAAAAQTDAVQDALEHLEDHQDKL 1841
Query: 503 AASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRC 562
+ R + D V +S+ LV AE HA Q LA L N L
Sbjct: 1842 LLWSAKIRHHIDDLVMHMSQR-NAVDLVYRAEDHAAEFQRLADVLYSGLENIRNVSLN-- 1898
Query: 563 AVDAATAYENILNAIKAAEDAANRA-ASASESALQTVIKEDLPRKAKTLSSNSDKLLNEA 621
A AA + NI + I+ +E+ A A + +E++L + E L K S + L E
Sbjct: 1899 ATSAAYVHYNIQSLIEESEELARDAHRTVTETSL---LSESLVSNGKAAVQRSSRFLKEG 1955
Query: 622 KMTQKKLK------QEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAM 675
+KL E+ N Q+ +T Q L + G+ +
Sbjct: 1956 NNLSRKLPGIALELSELRNKTNRFQENAVEITRQTNESLLILRAIPKGIRDKGAKTKELA 2015
Query: 676 ISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTN 735
S+++S V D+ + LN + R+ T T + L D+ +
Sbjct: 2016 TSASQSAVSTLRDVAGLSQELLNT-SASLSRVNTTLRETH-----QLLQDSTMATLLAGR 2069
Query: 736 KLPDLWRKIESINQQLLPLG----NISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVE 791
K+ D+ + + +L PL N+S N+ I+ LI QAR A+ + V + + + +
Sbjct: 2070 KVKDVEIQANLLFDRLKPLKMLEENLSRNLSEIKLLISQARKQAASIKVAVSAD-RDCIR 2128
Query: 792 VRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTC 851
P +L++ Q P++ + YLG+ AS D++ + + G++
Sbjct: 2129 AYQPQISSTNYNTLTLNVKTQEPDN---------LLFYLGSSTAS-DFLAVEMRRGRVAF 2178
Query: 852 VYNLGDREAELQVDQILTKSETKEAV----MDRVKFQRIYQFARLNYTKGATSSKPETPG 907
+++LG L+ ++ + + + + + TS P T
Sbjct: 2179 LWDLGSGSTRLEFPDFPIDDNRWHSIHVARFGNIGSLSVKEMSSNQKSPTKTSKSPGTAN 2238
Query: 908 VYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYN 967
V D+ N++TL+ +VGG K + +KGC+ LN + L+N
Sbjct: 2239 VLDV---NNSTLM---------FVGGLGGQIKKSPAVKVTHFKGCLGEAFLNGKSIGLWN 2286
Query: 968 FKKTFNLNTTEVEPCRRRKEESDKNY-FEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLL 1026
+ + + C + D ++ F+G+GY+ V A + T GLL
Sbjct: 2287 YIE----REGKCRGCFGSSQNEDPSFHFDGSGYSVVEKSLPATVTQIIMLFNTFSPNGLL 2342
Query: 1027 FFAEN-GDR-FISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRM 1084
+ + G + F+S+ + G++ V L S P NNG + I + + Q +
Sbjct: 2343 LYLGSYGTKDFLSIELFRGRVKVMTDLGSG-PITLLTDRRYNNGTWYKIAFQRNRKQGVL 2401
Query: 1085 WINVDVQNT----IIDGEV---------FDFSTYYLGGIPIAIRERFNISTPAFRGCMKN 1131
+ +D NT GE D Y+GG+P + R ++T +F GC+KN
Sbjct: 2402 AV-IDAYNTSNKETKQGETPGASSDLNRLDKDPIYVGGLPRSRVVRRGVTTKSFVGCIKN 2460
Query: 1132 LK-KTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQT 1190
L+ S L ++ GV K C + +RS SF +GG + L P +F T
Sbjct: 2461 LEISRSTFDLLRNSYGVRKGCLLE--PIRSVSFLKGGYIELPPKSLSPESEWLVTFA--T 2516
Query: 1191 FQPSGILLD------------HQTWTRNLQVTLEDGYIELSTSDS-GSPIFKS-----PQ 1232
SGI+L + V L G IE+ + G+ + K+
Sbjct: 2517 TNSSGIILAALGGDVEKRGDREEAHVPFFSVMLIGGNIEVHVNPGDGTGLRKALLHAPTG 2576
Query: 1233 TYMDGLLHYVSVISDNSGLRLLIDDQLLRNSK---RLKHISSSR----QSLRLGG----- 1280
T DG H +S++ + R +I QL N+ +L + SR +L +GG
Sbjct: 2577 TCSDGQAHSISLVRN----RRIITVQLDENNPVEMKLGTLVESRTINVSNLYVGGIPEGE 2632
Query: 1281 --------SNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGS 1332
+F GCI N L + E+LD S V L C L++ P L
Sbjct: 2633 GTSLLTMRRSFHGCIKN-----LIFNLELLDFNSAVGHEQVDLDTCWLSERPKL------ 2681
Query: 1333 TRFNKTKTFRINQLLQDTPVASPRSVKVWQDACSPLPKTQANHGALQFGDIPTSHLLFKL 1392
++LL + P A P V A +P GA QFG SH +
Sbjct: 2682 -----APDAEDSKLLPE-PRAFPEQCVV-DAALEYVP------GAHQFGLTQNSHFILPF 2728
Query: 1393 PQELLKPRSQFAVDMQTTSSRGLVFHTGTKNS--FMALYLSKGRLVFALGTDGKKLRIKS 1450
Q ++ + + ++T +S GL+++ +N + L L GRL F + ++
Sbjct: 2729 NQSAVRKKLSVELSIRTFASSGLIYYMAHQNQADYAVLQLHGGRLHFMFDLGKGRTKVSH 2788
Query: 1451 KEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGNST-ISIRAPVYLGSPPS---GK 1506
+DGKWHTV + KG + VDG + ++ G+ T + + YLG PS +
Sbjct: 2789 PALLSDGKWHTVKTDYVKRKGFITVDGRESPMVTVVGDGTMLDVEGLFYLGGLPSQYQAR 2848
Query: 1507 PKSLPTNSFVGCLKNFQLDSKPL--YTPSSSFGVSSCLGGPLEKGIYFSEEGGHVVLAHS 1564
T+S C+ + ++SK L +P S+F V+ C ++G YF G ++
Sbjct: 2849 KIGNITHSIPACIGDVTVNSKQLDKDSPVSAFTVNRCY-AVAQEGTYFDGSGYAALVKEG 2907
Query: 1565 VLLGPEFKLVFSIRPRSLTGILIHIGSQPGKHLCVYLEAGKVTASMDSGAGGTSTSVTPK 1624
+ + + R S G+L+ I + + + L GKV +++GAG + + PK
Sbjct: 2908 YKVQSDVNITLEFRTSSQNGVLLGISTAKVDAIGLELVDGKVLFHVNNGAGRITAAYEPK 2967
Query: 1625 QS--LCDGQWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPAS---TQEPLHLGGAPANL 1679
+ LCDG+WH++ +H + L D + + P ++ T P+++GG PA +
Sbjct: 2968 TATVLCDGKWHTLQANKSKH--RITLIVDGNAVGAESPHTQSTSVDTNNPIYVGGYPAGV 3025
Query: 1680 TTLRIPVWKSFFGCLRNIHVNHIP----VPVTEALEVQGPVSLNGCP 1722
+ SF GCLR + + P + A E+ G V L+ CP
Sbjct: 3026 KQKCLRSQTSFRGCLRKLALIKSPQVQSFDFSRAFELHG-VFLHSCP 3071
Score = 145 bits (365), Expect = 4e-34
Identities = 72/168 (42%), Positives = 95/168 (56%), Gaps = 13/168 (7%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
+ C GYYR L+ G C PC C+GH+ +C + G+C+ C HNT G HCE+C G+YG
Sbjct: 721 ESCLSGYYRVDGILFGGICQPCECHGHAAEC-NVHGVCIACAHNTTGVHCEQCLPGFYGE 779
Query: 117 AVHGS---CRACPCPHT---NSFATGCVVNGGD-VRCS-CKAGYTGTQCERCAPGYFGNP 168
G+ C+ C CP T N+F+ C +N GD V C C GY+G CERCA GY+GNP
Sbjct: 780 PSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCERCADGYYGNP 839
Query: 169 QKFGGSCQPCSCNSN---GQLGSCHPLTGDCIN-QEPKDSSPAEECDD 212
G SC PC C+ N + G C +TG+C+ D + E C D
Sbjct: 840 TVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
Score = 108 bits (270), Expect = 4e-23
Identities = 56/149 (37%), Positives = 79/149 (53%), Gaps = 18/149 (12%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNTAGEHCERCQEGY 113
C+ GYY + + CVPC+C+G+ + C +G C+ C NT G HCERC +G+
Sbjct: 831 CADGYY-GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADGF 889
Query: 114 YGNAVHG-SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
YG+AV +CRAC C S + C + G C CK TG QC++C GY+G G
Sbjct: 890 YGDAVTAKNCRACECHVKGSHSAVCHLETG--LCDCKPNVTGQQCDQCLHGYYGLDS--G 945
Query: 173 GSCQPCSCNSNGQL-------GSCHPLTG 194
C+PC+C+ G + G CH + G
Sbjct: 946 HGCRPCNCSVAGSVSDGCTDEGQCHCVPG 974
Score = 103 bits (256), Expect = 2e-21
Identities = 53/155 (34%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNG-HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
C+ G+Y D R C+ G HS C +G+C +C+ N G+ C++C GYYG
Sbjct: 885 CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVTGQQCDQCLHGYYGLD 943
Query: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
CR C C S + GC G +C C G G +C+RCA G++ GSC P
Sbjct: 944 SGHGCRPCNCSVAGSVSDGCTDEG---QCHCVPGVAGKRCDRCAHGFYAYQD---GSCTP 997
Query: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDD 212
C C +C P TG+C+ EEC+D
Sbjct: 998 CDCPHT--QNTCDPETGECVCPPHTQGVKCEECED 1030
Score = 92.0 bits (227), Expect = 4e-18
Identities = 57/188 (30%), Positives = 77/188 (40%), Gaps = 42/188 (22%)
Query: 59 CSPGYYRD--HKGLYTG--RCVPCNCNGHSNQCQ------------------DGSGICVN 96
C PGY++ G + C CNC+ + C G G+C+N
Sbjct: 304 CCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN 363
Query: 97 CQHNTAGEHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVV--------NGGD 143
C NT G +CE C +GYY CR C C S ++ C+ NG
Sbjct: 364 CLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ 423
Query: 144 V-RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
+C CK GYTG +C+RC GY P +C C CN G S P TG C+ +E
Sbjct: 424 PGQCPCKEGYTGEKCDRCQLGYKDYP-----TCVSCGCNPVGS-ASDEPCTGPCVCKENV 477
Query: 203 DSSPAEEC 210
+ + C
Sbjct: 478 EGKACDRC 485
Score = 90.5 bits (223), Expect = 1e-17
Identities = 54/172 (31%), Positives = 76/172 (44%), Gaps = 19/172 (11%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAV 118
C+ G+Y G C PC+C N C +G CV C +T G CE C++G++G
Sbjct: 983 CAHGFY----AYQDGSCTPCDCPHTQNTCDPETGECV-CPPHTQGVKCEECEDGHWGYDA 1037
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
C+AC C S C V G C CK+ + G C++C+ GY P C PC
Sbjct: 1038 EVGCQACNCSLVGSTHHRCDVVTG--HCQCKSKFGGRACDQCSLGYRDFP-----DCVPC 1090
Query: 179 SCNSNGQLG-SCHPLTGDCINQEPKDSSPAEE------CDDCDSCVMTLLND 223
C+ G G +C+ G C E + P +E C++C L D
Sbjct: 1091 DCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRAD 1142
Score = 70.9 bits (172), Expect = 1e-11
Identities = 55/188 (29%), Positives = 71/188 (37%), Gaps = 37/188 (19%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYY----- 114
YY K + G C C GH++ C + + C+HNT GE C RC GY+
Sbjct: 257 YYYSIKDISVGGM--CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWR 314
Query: 115 -GNAVHG-SCRACPC--------------PHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
G G +C AC C S T GG V +C G CE
Sbjct: 315 PGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE 374
Query: 159 RCAPGYFGNPQKFG----GSCQPCSCNSNGQLGSC---HPLTGDCINQEPKDSSPAEE-- 209
C GY+ P K C+PC+C+ G L S L D N + P +E
Sbjct: 375 TCIDGYY-RPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGY 433
Query: 210 -CDDCDSC 216
+ CD C
Sbjct: 434 TGEKCDRC 441
Score = 54.7 bits (130), Expect = 8e-07
Identities = 38/109 (34%), Positives = 50/109 (45%), Gaps = 18/109 (16%)
Query: 131 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFG-NPQKFGGSCQPC-------SCNS 182
+S A VV C C GYTGT CE C GY+ + FGG CQPC CN
Sbjct: 694 SSNAIDLVVAADVEHCECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNV 753
Query: 183 NGQLGSC-HPLTGDCINQ-------EPKDSSPAEECDDCDSCVMTLLND 223
+G +C H TG Q EP +P +C C +C +T+ ++
Sbjct: 754 HGVCIACAHNTTGVHCEQCLPGFYGEPSRGTPG-DCQPC-ACPLTIASN 800
Score = 54.7 bits (130), Expect = 8e-07
Identities = 28/79 (35%), Positives = 37/79 (46%), Gaps = 13/79 (16%)
Query: 146 CSCKAGYTGTQCERCAPGYFGN---------PQKFGGSCQPCSCNSNGQLGSCHPLTGDC 196
C C G G C+ CAPGY P+ C PCSCN++ +C P TG C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSD--TCDPNTGKC 1419
Query: 197 INQEPKDSSPAEECDDCDS 215
+N D++ + CD C S
Sbjct: 1420 LN--CGDNTAGDHCDVCTS 1436
Score = 36.2 bits (82), Expect = 0.28
Identities = 26/86 (30%), Positives = 33/86 (38%), Gaps = 19/86 (22%)
Query: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCN--GHSNQ----------CQDGSGICVNCQHNT 101
R CS GY RD CVPC+C+ G S C + +G C C+ N
Sbjct: 1072 RACDQCSLGY-RDFPD-----CVPCDCDLRGTSGDACNLEQGLCGCVEETGACP-CKENV 1124
Query: 102 AGEHCERCQEGYYGNAVHGSCRACPC 127
G C C+EG + PC
Sbjct: 1125 FGPQCNECREGTFALRADNPLGCSPC 1150
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 139 bits (350), Expect = 2e-32
Identities = 65/129 (50%), Positives = 76/129 (58%), Gaps = 8/129 (6%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Q C+PGY R GLY G C C CNGHS+ C +G C CQHN AGE CE C GYYG+
Sbjct: 1542 QDCAPGYTRTGSGLYLGHCELCECNGHSDLCHPETGACSQCQHNAAGEFCELCAPGYYGD 1601
Query: 117 AVHGS---CRACPCPHT---NSFATGC-VVNGGDVRC-SCKAGYTGTQCERCAPGYFGNP 168
A G+ C+ C CP T N F+ C + G RC +C+ GYTG CE+C PGY GNP
Sbjct: 1602 ATAGTPEDCQPCACPLTNPENMFSRTCESLGAGGYRCTACEPGYTGQYCEQCGPGYVGNP 1661
Query: 169 QKFGGSCQP 177
GG C P
Sbjct: 1662 SVQGGQCLP 1670
Score = 130 bits (328), Expect = 8e-30
Identities = 65/157 (41%), Positives = 84/157 (53%), Gaps = 18/157 (11%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
Q C GY R GLY G C C+C+GHS C+ +G C CQH+T G CE+CQ GYYG+
Sbjct: 1138 QDCDTGYTRTPSGLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGD 1197
Query: 117 AVHGS---CRACPC---PHTNSFATGCVVN-GGDVRC-SCKAGYTGTQCERCAPGYFGNP 168
A G+ C+ CPC P A C ++ G C +C G++G CERCAPGY+GNP
Sbjct: 1198 AQRGTPQDCQLCPCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNP 1257
Query: 169 QKFGGSCQ---------PCSCNSNGQLGSCHPLTGDC 196
+ G CQ C+C+ G + S G C
Sbjct: 1258 SQ-GQPCQRDSQVPGPIGCNCDPQGSVSSQCDAAGQC 1293
Score = 130 bits (327), Expect = 1e-29
Identities = 60/145 (41%), Positives = 85/145 (58%), Gaps = 13/145 (8%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
+ C + R G Y G C CNCNGH++ C G C+NCQHNT G C +C+ G++G+
Sbjct: 743 ESCDAHFTRVPGGPYLGTCSGCNCNGHASSCDPVYGHCLNCQHNTEGPQCNKCKAGFFGD 802
Query: 117 AVHG---SCRACPCPHTNS---FATGCVVN-GGDVRC-SCKAGYTGTQCERCAPGYFGNP 168
A+ SCR CPCP+ ++ F+ C ++ G C +C GYTG +CE CAPGY GNP
Sbjct: 803 AMKATATSCRPCPCPYIDASRRFSDTCFLDTDGQATCDACAPGYTGRRCESCAPGYEGNP 862
Query: 169 QKFGGSCQPCS-----CNSNGQLGS 188
+ GG C+P + C+ G +G+
Sbjct: 863 IQPGGKCRPVNQEIVRCDERGSMGT 887
Score = 76.3 bits (186), Expect = 2e-13
Identities = 54/181 (29%), Positives = 63/181 (34%), Gaps = 22/181 (12%)
Query: 19 GAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPC 78
G LG C S G Q + E + C PGYY D + C C
Sbjct: 1150 GLYLGTCERCSCHGHSEACEPETGACQGCQHHTEGPRCEQCQPGYYGDAQRGTPQDCQLC 1209
Query: 79 NCNGHSNQCQ---------DGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS-CR----- 123
C G Q DG C C +G HCERC GYYGN G C+
Sbjct: 1210 PCYGDPAAGQAAHTCFLDTDGHPTCDACSPGHSGRHCERCAPGYYGNPSQGQPCQRDSQV 1269
Query: 124 ----ACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCS 179
C C S ++ C G +C CKA G C C P +F C PC
Sbjct: 1270 PGPIGCNCDPQGSVSSQCDAAG---QCQCKAQVEGLTCSHCRPHHFHLSASNPDGCLPCF 1326
Query: 180 C 180
C
Sbjct: 1327 C 1327
Score = 61.6 bits (148), Expect = 6e-09
Identities = 38/132 (28%), Positives = 65/132 (49%), Gaps = 10/132 (7%)
Query: 1405 VDMQTTSSRGLVFHTGTK-------NSFMALYLSKGRLVFALGTDGKKLRIKSKEKCNDG 1457
++++T+++ GL+ G + F++L L G LVF + R+ S++ NDG
Sbjct: 4232 LEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDG 4291
Query: 1458 KWHTVVFGHDGEKGRLVVDGLRAREGSLPG-NSTISIRAPVYLGSPP--SGKPKSLPTNS 1514
+WH V +G +G + VDG G PG N ++ + VY+G P + ++
Sbjct: 4292 EWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSG 4351
Query: 1515 FVGCLKNFQLDS 1526
GC+KN L S
Sbjct: 4352 ITGCVKNLVLHS 4363
Score = 53.1 bits (126), Expect = 2e-06
Identities = 26/69 (37%), Positives = 35/69 (50%), Gaps = 5/69 (7%)
Query: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C C GY G C+ CAPGY + G C+ C CN + L CHP TG C + + +
Sbjct: 1530 CRCPPGYIGLSCQDCAPGYTRTGSGLYLGHCELCECNGHSDL--CHPETGAC--SQCQHN 1585
Query: 205 SPAEECDDC 213
+ E C+ C
Sbjct: 1586 AAGEFCELC 1594
Score = 51.2 bits (121), Expect = 9e-06
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 145 RCSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 203
+CSC GY G C+ C GY P + G+C+ CSC+ + + +C P TG C +
Sbjct: 1125 QCSCPPGYRGPSCQDCDTGYTRTPSGLYLGTCERCSCHGHSE--ACEPETGACQGCQHHT 1182
Query: 204 SSPAEECDDC 213
P C+ C
Sbjct: 1183 EGP--RCEQC 1190
Score = 50.4 bits (119), Expect = 1e-05
Identities = 24/69 (34%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 146 CSCKAGYTGTQCERCAPGYFGNPQ-KFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDS 204
C C GY+G CE C + P + G+C C+CN G SC P+ G C+N +
Sbjct: 731 CRCPIGYSGLSCESCDAHFTRVPGGPYLGTCSGCNCN--GHASSCDPVYGHCLNCQHNTE 788
Query: 205 SPAEECDDC 213
P +C+ C
Sbjct: 789 GP--QCNKC 795
Score = 43.1 bits (100), Expect = 0.002
Identities = 40/148 (27%), Positives = 64/148 (43%), Gaps = 11/148 (7%)
Query: 1405 VDMQTTSSRGLVFHTGTKNS----FMALYLSKGRLVFALGTDGKKLRIKSKEKCNDGKWH 1460
V+ + + G++ +G K+ F++L + G L F ++S E G+WH
Sbjct: 3955 VEFKPLAPDGVLLFSGGKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGRWH 4014
Query: 1461 TVVFGHDGEKGRLVVDGLRAREGSLPGNST-ISIRAPVYLGSPPSGKPKSLPTN---SFV 1516
V + G L V+G R S PG S +++ +YLG P S TN F
Sbjct: 4015 RVSAERLNKDGSLRVNGGRPVLRSSPGKSQGLNLHTLLYLGGVEPSVPLSPATNMSAHFR 4074
Query: 1517 GCLKNFQLDSKPL---YTPSSSFGVSSC 1541
GC+ ++ K L Y+ S G+ C
Sbjct: 4075 GCVGEVSVNGKRLDLTYSFLGSQGIGQC 4102
Score = 39.7 bits (91), Expect = 0.026
Identities = 45/163 (27%), Positives = 66/163 (40%), Gaps = 31/163 (19%)
Query: 993 YFEGTGYARVP------TQPHAPIPTFGQTIQTTVDRGLLFF-------AENGDRFISLN 1039
YF G+ P + P P T ++T+ GLL + A G FISL
Sbjct: 4205 YFHDDGFLAFPGHVFSRSLPEVP-ETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLG 4263
Query: 1040 IEDGKLMVRYKLNS---ELPKERGVGD-------AINNGRDHSIQIKIGKLQKRMWINVD 1089
++DG L+ RY+L S L E + D A+ GR SIQ+ +L V
Sbjct: 4264 LQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEEL-------VS 4316
Query: 1090 VQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNL 1132
++ + V + Y+GG P + GC+KNL
Sbjct: 4317 GRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNL 4359
Score = 35.8 bits (81), Expect = 0.37
Identities = 32/159 (20%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 1402 QFAVDMQTTSSRGLVFHTGTKN-------------SFMALYLSKGRLVFALGTDGKKLRI 1448
+ + + S+ G++ + G K F++ L GR F I
Sbjct: 3687 EIKITFRPDSADGMLLYNGQKRVPGSPTNLANRQPDFISFGLVGGRPEFRFDAGSGMATI 3746
Query: 1449 KSKEKCNDGKWHTVVFGHDGEKGRLVVDGLRAREGSLPGN-STISIRAPVYLGSPP--SG 1505
+ G +HTV +G L+V L G+ G + + +YLG P
Sbjct: 3747 RHPTPLALGHFHTVTLLRSLTQGSLIVGDLAPVNGTSQGKFQGLDLNEELYLGGYPDYGA 3806
Query: 1506 KPKSLPTNSFVGCLKNFQLDSKPLYTPS---SSFGVSSC 1541
PK+ ++ F+GC++ ++ + + ++ G+S C
Sbjct: 3807 IPKAGLSSGFIGCVRELRIQGEEIVFHDLNLTAHGISHC 3845
Score = 33.9 bits (76), Expect = 1.4
Identities = 27/89 (30%), Positives = 34/89 (38%), Gaps = 15/89 (16%)
Query: 72 TGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTN 131
T R PC G + + S +CV C G CE Q A+H AC T
Sbjct: 3847 TCRDRPCQNGGQCHDSESSSYVCV-CPAGFTGSRCEHSQ------ALHCHPEACGPDAT- 3898
Query: 132 SFATGCV--VNGGDVRCSCKAGYTGTQCE 158
CV +G C C G +G +CE
Sbjct: 3899 -----CVNRPDGRGYTCRCHLGRSGLRCE 3922
Score = 32.7 bits (73), Expect = 3.1
Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 20/158 (12%)
Query: 831 GNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFA 890
G D++ +A+V G L Y LG A L+ + L RV +R+ +
Sbjct: 3971 GKSGPVEDFVSLAMVGGHLEFRYELGSGLAVLRSAEPLALGR-----WHRVSAERLNKDG 4025
Query: 891 RLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKL-PSRLSFPPY 949
L G + +PG G N +TLL Y+GG P L P+ +
Sbjct: 4026 SLRVNGGRPVLR-SSPG--KSQGLNLHTLL---------YLGGVEPSVPLSPATNMSAHF 4073
Query: 950 KGCIELDDLNENVLSL-YNFKKTFNLNTT-EVEPCRRR 985
+GC+ +N L L Y+F + + + PC R+
Sbjct: 4074 RGCVGEVSVNGKRLDLTYSFLGSQGIGQCYDSSPCERQ 4111
Score = 31.6 bits (70), Expect = 7.0
Identities = 19/60 (31%), Positives = 24/60 (40%), Gaps = 4/60 (6%)
Query: 122 CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA-PGYFGNPQKFGGSCQPCSC 180
C PC H AT + +C C+ G+ G CE P P GG+CQ C
Sbjct: 4108 CERQPCQHG---ATCMPAGEYEFQCLCRDGFKGDLCEHEENPCQLREPCLHGGTCQGTRC 4164
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 134 bits (338), Expect = 6e-31
Identities = 60/135 (44%), Positives = 80/135 (59%), Gaps = 12/135 (8%)
Query: 75 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA---VHGSCRACPCPH-- 129
C PC CNGH+++C +G C+ C+ +T GEHCERC G++G+ G CR CPCP
Sbjct: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
Query: 130 --TNSFATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSN-- 183
FAT C + + C C+AGYTG +CE CAPG+FG+P + GG CQ C C+ N
Sbjct: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
Query: 184 -GQLGSCHPLTGDCI 197
+C P TG C+
Sbjct: 994 PMDPDACDPHTGQCL 1008
Score = 99.0 bits (245), Expect = 4e-20
Identities = 55/162 (33%), Positives = 79/162 (48%), Gaps = 17/162 (10%)
Query: 55 PSQGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQE 111
PS+ C+P +Y G +PC CN S++C G C+ C+ G C+ C
Sbjct: 761 PSEACAPLLISLSTLIYNG-ALPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAP 818
Query: 112 GYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKF 171
GYYG G C+AC C H + ++ C G +C C+ G G +C+RC G +G P
Sbjct: 819 GYYGFGPTG-CQACQCSHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP--- 872
Query: 172 GGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
SC+PC C NG C+ TG C+ +D + E C+ C
Sbjct: 873 --SCRPCVC--NGHADECNTHTGACLG--CRDHTGGEHCERC 908
Score = 99.0 bits (245), Expect = 4e-20
Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 16/178 (8%)
Query: 47 QASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQHNT 101
+A Y R + C+PG++ D GRC C C+G+ + C +G C+ C H+T
Sbjct: 957 RAGYTGLR-CEACAPGHFGD-PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHT 1014
Query: 102 AGEHCERCQEGYYGNAVHGSCRACPC------PHTNSFATGCVVNGGDVRCSCKAGYTGT 155
G HC C+ G++G A SC C C P C + +C C G
Sbjct: 1015 EGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
Query: 156 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDD 212
C+RCAP ++ G CQPC+C+ + G +C+ TG C + EC +
Sbjct: 1075 SCDRCAPNFWNLTS--GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQE 1130
Score = 87.0 bits (214), Expect = 1e-16
Identities = 56/207 (27%), Positives = 88/207 (42%), Gaps = 35/207 (16%)
Query: 25 CLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCS----PGYYRD-----HKGLYTGRC 75
C G++S+ P + + + + ++G + +YRD + ++ C
Sbjct: 285 CYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHAC 344
Query: 76 VPCNCNGHSNQCQD-----------GSGICVNCQHNTAGEHCERCQEGYYGNAVH----- 119
C C+GH++ C G+C CQHNTAG HCE C+ +Y +
Sbjct: 345 RKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDP 404
Query: 120 GSCRACPCPHTNSFATGCVVNGGDV-------RCSCKAGYTGTQCERCAPGYFGNPQKFG 172
CR+C C S G + D +C CK GT+C++C G+FG
Sbjct: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR 464
Query: 173 GSCQPCSCNSNGQL-GS--CHPLTGDC 196
C+ C CN+ G + GS C P +G C
Sbjct: 465 LGCRRCQCNARGTVPGSTPCDPNSGSC 491
Score = 75.5 bits (184), Expect = 4e-13
Identities = 49/157 (31%), Positives = 69/157 (43%), Gaps = 23/157 (14%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG--------------SGICVNCQHNTAGE 104
C P +YRD V +C+ QDG SG C C+ + G
Sbjct: 389 CRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGT 447
Query: 105 HCERCQEGYYGNAVHG--SCRACPCPHTNSF--ATGCVVNGGDVRCSCKAGYTGTQCERC 160
C++C++G++G ++ CR C C + +T C N G C CK TG C+RC
Sbjct: 448 RCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRC 505
Query: 161 APGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC 196
PG++G G C+PC C+ G L C TG C
Sbjct: 506 LPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQC 541
Score = 61.2 bits (147), Expect = 8e-09
Identities = 53/190 (27%), Positives = 80/190 (42%), Gaps = 46/190 (24%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAGEHCERCQE 111
YY ++ + G C C GH+++C G C+ C+HNT G +CE+CQ+
Sbjct: 271 YYALYELVVRGNCF---CYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD 326
Query: 112 GY----YGNAVHG---SCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 155
Y + A G +CR C C HT+S A+G V G V C+ G
Sbjct: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV--SGGVCDGCQHNTAGR 384
Query: 156 QCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL--GSCHP--------LTGDCINQEPK 202
CE C P ++ +P K C+ C C+ G G C ++G C +E
Sbjct: 385 HCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHV 444
Query: 203 DSSPAEECDD 212
+ ++C D
Sbjct: 445 VGTRCQQCRD 454
Score = 56.2 bits (134), Expect = 3e-07
Identities = 32/98 (32%), Positives = 43/98 (43%), Gaps = 11/98 (11%)
Query: 75 CVPCNCNGH-----SNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPC 127
C C CN S C SG C C+ G C+RC G++G + H CR C C
Sbjct: 467 CRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
Query: 128 PHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 165
+ C + G +C C+ G +CE+ PGYF
Sbjct: 525 DVGGALDPQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 134 bits (336), Expect = 1e-30
Identities = 67/156 (42%), Positives = 86/156 (55%), Gaps = 18/156 (11%)
Query: 54 RPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGY 113
R C PG H G + C PC CNGH++ C +G C+NCQ T G +CERC GY
Sbjct: 849 RQCDRCLPG----HWGFPS--CQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGY 902
Query: 114 YGNAVHGS---CRACPCP----HTNSFATGCVVNGGDVR--CSCKAGYTGTQCERCAPGY 164
YG+ + GS CR CPCP FA C + ++ C C GY G++C+ CA GY
Sbjct: 903 YGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962
Query: 165 FGNPQKFGGSCQPCSCNSN---GQLGSCHPLTGDCI 197
FGNP + GGSCQPC C++N +C TG C+
Sbjct: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCL 998
Score = 115 bits (288), Expect = 4e-25
Identities = 158/792 (19%), Positives = 299/792 (37%), Gaps = 113/792 (14%)
Query: 50 YVEFRPSQGCSPGYYRDHKGLYTGRCVPCN--------CNGHSNQCQDGSGICVNCQHNT 101
+ E Q C GYY D +CV CN CNG QC +G C+ C N
Sbjct: 1003 HTEGEHCQFCRFGYYGDALQQDCRKCV-CNYLGTVQEHCNGSDCQCDKATGQCL-CLPNV 1060
Query: 102 AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 161
G++C+RC + A C C C +SF C N +C C G+ G C C
Sbjct: 1061 IGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSC--NEFTGQCQCMPGFGGRTCSECQ 1118
Query: 162 PGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEEC--------DD 212
++G+P C+ C C+ G + C TG C+ E + ++C D
Sbjct: 1119 ELFWGDPDV---ECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPD 1175
Query: 213 CDSCVM------TLLNDLATMGEQLRLVKSQLQGLSASAG-LLEQMRHMETQAKDLRNQL 265
C C ++ +L + L K++ +S G E + +E + ++++ L
Sbjct: 1176 CTPCHQCFALWDVIIAELTNRTHRF-LEKAKALKISGVIGPYRETVDSVERKVSEIKDIL 1234
Query: 266 LNYRSA--ISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKE 323
+A + N G+ E E+ + D+ + ++ K L++ +++ +AKE
Sbjct: 1235 AQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVK----------LSDTTSQSNSTAKE 1284
Query: 324 LD------VKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFG 377
LD + N ++ + L+ I +D G + + EA+ +
Sbjct: 1285 LDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNS 1344
Query: 378 KHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEY--------------- 422
+ A R +++ R + K Q E L + + L
Sbjct: 1345 TVEQSALMRDRVEDVMMER-ESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPG 1403
Query: 423 ----EAKLSDLRARLQEAAAQA----------------KQANGLNQENERALGAIQRQVK 462
E + R E + ++A L+Q+ AL +++ K
Sbjct: 1404 ASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSK 1463
Query: 463 EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSR 522
++ + + +A+ LL+TN + M+KS +E L + + S + +
Sbjct: 1464 MVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEA 1523
Query: 523 SAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAED 582
A + L E + LQ L + + E + S E++ ++ I AE
Sbjct: 1524 VANEV-LKMEMPSTPQQLQNLTEDIRERVESLSQVEVI---------LQHSAADIARAEM 1573
Query: 583 AANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQT 642
A AS+SA + D+ ++A L EA+ Q ++ + A ++Q T
Sbjct: 1574 LLEEAKRASKSATDVKVTADMVKEA----------LEEAEKAQVAAEKAIKQADEDIQGT 1623
Query: 643 LNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQT 702
N++T + + TL + I +++ + K + + + + + ++
Sbjct: 1624 QNLLTSIESETAASEETLFNASQRI--SELERNVEELKRKAAQNSGEAEYIEKVVYTVKQ 1681
Query: 703 DVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESI-NQQLLPLGNISDNM 761
E +K T +E +KK +N + K T + D RK E + N+ L + +
Sbjct: 1682 SAEDVKKTLDGELDEKYKK----VENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKL 1737
Query: 762 DRIRELIQQARD 773
+++L ++ D
Sbjct: 1738 QLLKDLERKYED 1749
Score = 88.6 bits (218), Expect = 5e-17
Identities = 51/143 (35%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Query: 72 TGRCVPCNCNGH-SNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHT 130
TG C+ G S+ C G C C+ N G C RC G +G G C+ C C
Sbjct: 769 TGLACECDPQGSLSSVCDPNGGQC-QCRPNVVGRTCNRCAPGTFGFGPSG-CKPCECHLQ 826
Query: 131 NSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCH 190
S C N +C C G QC+RC PG++G P SCQPC C NG C
Sbjct: 827 GSVNAFC--NPVTGQCHCFQGVYARQCDRCLPGHWGFP-----SCQPCQC--NGHADDCD 877
Query: 191 PLTGDCINQEPKDSSPAEECDDC 213
P+TG+C+N + D + C+ C
Sbjct: 878 PVTGECLNCQ--DYTMGHNCERC 898
Score = 84.0 bits (206), Expect = 1e-15
Identities = 51/188 (27%), Positives = 74/188 (39%), Gaps = 31/188 (16%)
Query: 64 YRDHKGLYTGRCVPCNCNGHSNQCQD-----------GSGICVNCQHNTAGEHCERCQEG 112
+R +G + C CNCN HS C G+C +CQHNT G +CE+C+
Sbjct: 321 WRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPF 380
Query: 113 YYGNAVH-----GSCRACPCPHTNS-----------FATGCVVNGGDVRCSCKAGYTGTQ 156
YY + C C C S F+TG + +C CK G
Sbjct: 381 YYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAG----QCRCKLNVEGEH 436
Query: 157 CERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSC 216
C+ C G++ + C+ C+CN G + +P + + K + CD C
Sbjct: 437 CDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPE 496
Query: 217 VMTLLNDL 224
L NDL
Sbjct: 497 HWGLSNDL 504
Score = 74.3 bits (181), Expect = 9e-13
Identities = 48/164 (29%), Positives = 68/164 (41%), Gaps = 27/164 (16%)
Query: 54 RPSQGCSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGIC--------------V 95
R + C P YY RD + C C C+ +Q GIC
Sbjct: 372 RNCEQCKPFYYQHPERDIRD--PNFCERCTCDPAGSQ---NEGICDSYTDFSTGLIAGQC 426
Query: 96 NCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 153
C+ N GEHC+ C+EG+Y + C++C C + G + C CK T
Sbjct: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVT 486
Query: 154 GTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GSCHPLTGDC 196
G C++C P ++G G C+PC C+ G L SC +G C
Sbjct: 487 GQHCDQCLPEHWGLSNDLDG-CRPCDCDLGGALNNSCFAESGQC 529
Score = 67.4 bits (163), Expect = 1e-10
Identities = 37/98 (37%), Positives = 50/98 (51%), Gaps = 11/98 (11%)
Query: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGS-CQ 176
+H + AC C S ++ C NGG +C C+ G C RCAPG FG FG S C+
Sbjct: 766 LHQTGLACECDPQGSLSSVCDPNGG--QCQCRPNVVGRTCNRCAPGTFG----FGPSGCK 819
Query: 177 PCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
PC C+ G + + C+P+TG C A +CD C
Sbjct: 820 PCECHLQGSVNAFCNPVTGQC---HCFQGVYARQCDRC 854
Score = 60.1 bits (144), Expect = 2e-08
Identities = 34/113 (30%), Positives = 48/113 (42%), Gaps = 10/113 (8%)
Query: 59 CSPGYY----RDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYY 114
C G+Y D G + C P N C +G C C+ G+HC++C ++
Sbjct: 440 CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY-CKRLVTGQHCDQCLPEHW 498
Query: 115 G--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF 165
G N + G CR C C + C G +CSC+ G QC PGY+
Sbjct: 499 GLSNDLDG-CRPCDCDLGGALNNSCFAESG--QCSCRPHMIGRQCNEVEPGYY 548
Score = 58.2 bits (139), Expect = 7e-08
Identities = 54/191 (28%), Positives = 77/191 (40%), Gaps = 49/191 (25%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQ--DG---------SGICVNCQHNTAGEHCERCQE 111
YY + + G C C GH+++C DG G C+ C+HNT G +CE C +
Sbjct: 259 YYAVYDMVVRGNCF---CYGHASECAPVDGFNEEVEGMVHGHCM-CRHNTKGLNCELCMD 314
Query: 112 GYYG-------NAVHGSCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 155
Y+ +C+ C C H+ S ATG V G V C+ G
Sbjct: 315 FYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNV--SGGVCDDCQHNTMGR 372
Query: 156 QCERCAPGYFGNPQ---KFGGSCQPCSCNSNGQL--GSCHPLT--------GDCINQEPK 202
CE+C P Y+ +P+ + C+ C+C+ G G C T G C K
Sbjct: 373 NCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC---RCK 429
Query: 203 DSSPAEECDDC 213
+ E CD C
Sbjct: 430 LNVEGEHCDVC 440
Score = 40.8 bits (94), Expect = 0.012
Identities = 64/343 (18%), Positives = 143/343 (41%), Gaps = 49/343 (14%)
Query: 212 DCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAG--LLEQ---MRHMETQAKDLRNQLL 266
D D V++ L ++ + + + K + SA LL+ M+ ++LRN +
Sbjct: 1446 DLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIK 1505
Query: 267 NYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDV 326
R+ ++ + ++ +E E L+ + ++ Q L ++ +S +++V
Sbjct: 1506 QIRNFLTQDSADLDSIEAVAN------EVLKMEMPSTPQQLQNLTEDIRERVESLSQVEV 1559
Query: 327 KIKNV---IRNVHILLKQISGTDGEGNNVP-SGDFSREWAEAQRMMRELRNRNFGKHLRE 382
+++ I +LL++ +V + D +E E + K +++
Sbjct: 1560 ILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAE----KAIKQ 1615
Query: 383 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA-- 440
A+ D + +Q LL I + +T E S R ++E E + +L+ + + + +A
Sbjct: 1616 ADEDIQGTQNLLTSIES--ETAASEETLFNASQR--ISELERNVEELKRKAAQNSGEAEY 1671
Query: 441 ----------------KQANG-LNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLL 483
K +G L+++ ++ I ++ +E + A + L
Sbjct: 1672 IEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLA 1731
Query: 484 QTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGK 526
Q N LQL++ +++YE + ++ L DK +EL+R G+
Sbjct: 1732 QANSKLQLLKDLERKYE-------DNQRYLEDKAQELARLEGE 1767
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 127 bits (320), Expect = 7e-29
Identities = 61/133 (45%), Positives = 76/133 (57%), Gaps = 10/133 (7%)
Query: 75 CVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGS-CRACPCPHTNS- 132
C PC CN + C +G C NC T G +CERC +GYYGN G CR C CP S
Sbjct: 860 CHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSS 919
Query: 133 ---FATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL- 186
FA C N DV C+C GYTGTQC C+ G++GNP+ G CQPC+CN+N +
Sbjct: 920 NQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVT 979
Query: 187 --GSCHPLTGDCI 197
SC +TG+C+
Sbjct: 980 DPESCSRVTGECL 992
Score = 97.4 bits (241), Expect = 1e-19
Identities = 53/167 (31%), Positives = 75/167 (44%), Gaps = 16/167 (9%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQEGY 113
CS G+Y + + + C PC CN + + C +G C+ C HNT G +C+ C+ G+
Sbjct: 952 CSTGFYGNPR-ISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGH 1010
Query: 114 YGNAVHGSCRACPCPHTNSFATGCVVNGGDV-------RCSCKAGYTGTQCERCAPGYFG 166
YG+A++ +CR C C + C GG C C TG C+RCA GY+
Sbjct: 1011 YGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWN 1070
Query: 167 NPQKFGGSCQPCSCN-SNGQLGSCHPLTGDCINQEPKDSSPAEECDD 212
G CQ C C+ Q C LTG C + EC +
Sbjct: 1071 LVP--GRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQE 1115
Score = 96.7 bits (239), Expect = 2e-19
Identities = 61/223 (27%), Positives = 89/223 (39%), Gaps = 37/223 (16%)
Query: 25 CLGYSS-----QQQRVPFLQPPGQSQLQASYVEFRPSQGCS-------PGYYRDHKGLYT 72
C G++S Q+ R PPG Q C +R L
Sbjct: 267 CNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQD 326
Query: 73 GRCVPCNCNGHSNQCQD-----------GSGICVNCQHNTAGEHCERCQEGYYGNAVHG- 120
C C+CN HS++C G+C +CQHNT G+HC+RC+ +Y + +
Sbjct: 327 NACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTI 386
Query: 121 ----SCRACPCPHTNSFATGCVVNGGDV-------RCSCKAGYTGTQCERCAPGYFGNPQ 169
+C C C + + G V+ D +C CK G +C++C P ++G
Sbjct: 387 SDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSA 446
Query: 170 KFGGSCQPCSCNSNGQLG--SCHPLTGDCINQEPKDSSPAEEC 210
CQPC CN G L +C TG C+ + EEC
Sbjct: 447 TDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEEC 489
Score = 94.7 bits (234), Expect = 7e-19
Identities = 79/294 (26%), Positives = 118/294 (40%), Gaps = 44/294 (14%)
Query: 57 QGCSPGYYRDHKGLYTGRCVPCNCNGHSN-QCQDGSGICV--------NCQHNTAGEHCE 107
Q C PG+Y RC C+ +G S +C G G C+ C N G C+
Sbjct: 1004 QLCKPGHYGSALNQTCRRC-SCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD 1062
Query: 108 RCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGN 167
RC +GY+ C++C C S ++ C G +C CK GY G +C C Y+G+
Sbjct: 1063 RCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTG--QCPCKLGYGGKRCSECQENYYGD 1120
Query: 168 PQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEEC-----DDCDSCVMTLL 221
P G C PC CN G Q C P TG C +E + C + +C+ L
Sbjct: 1121 PP---GRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHL 1177
Query: 222 NDLATMGEQLRLVKSQLQGLSASAGLLEQMRH----METQAKDLR------NQLLNYRSA 271
+ + +QGL A +E R E KDLR ++L +
Sbjct: 1178 -CFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVF 1236
Query: 272 ISNHGSKI----EGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSA 321
S K+ + + R++ LN++ + + E Q L + + RA A
Sbjct: 1237 PSGKFLKVKDYHDSVRRQIMQLNEQLKAVYE--------FQDLKDTIERAKNEA 1282
Score = 78.6 bits (192), Expect = 5e-14
Identities = 49/132 (37%), Positives = 57/132 (43%), Gaps = 13/132 (9%)
Query: 67 HKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACP 126
H G +C P G S C G C C+ G C+RC G Y HG C C
Sbjct: 763 HDGAVACKCHPQGSVGSS--CSRLGGQC-QCKPLVVGRCCDRCSTGSYDLGHHG-CHPCH 818
Query: 127 CPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL 186
C S T C G +C C +G +C+RC GYFG P SC PC CN +L
Sbjct: 819 CHPQGSKDTVCDQVTG--QCPCHGEVSGRRCDRCLAGYFGFP-----SCHPCPCNRFAEL 871
Query: 187 GSCHPLTGDCIN 198
C P TG C N
Sbjct: 872 --CDPETGSCFN 881
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/192 (26%), Positives = 83/192 (43%), Gaps = 51/192 (26%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGS--------------GICVNCQHNTAGEHCER 108
YY ++ + G C CNGH+++C+ G CV CQHNT G +CER
Sbjct: 253 YYALYEMIVRGSCF---CNGHASECRPMQKMRGDVFSPPGMVHGQCV-CQHNTDGPNCER 308
Query: 109 CQEGYY-------GNAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAG 151
C++ + + +CR+C C NS ++ C + G V C+
Sbjct: 309 CKDFFQDAPWRPAADLQDNACRSCSC---NSHSSRCHFDMTTYLASGGLSGGVCEDCQHN 365
Query: 152 YTGTQCERCAPGYFGNPQKFGG---SCQPCSCNSNGQL--GSC--------HPLTGDCIN 198
G C+RC P ++ +P K +C PC C+ +G + G C + G C+
Sbjct: 366 TEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLC 425
Query: 199 QEPKDSSPAEEC 210
+E + + ++C
Sbjct: 426 KENVEGAKCDQC 437
Score = 68.9 bits (167), Expect = 4e-11
Identities = 43/127 (33%), Positives = 55/127 (43%), Gaps = 11/127 (8%)
Query: 51 VEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSN----QCQDGSGICVNCQHNTAGEHC 106
VE C P +Y G C PC+CN + C +G C+ C G HC
Sbjct: 429 VEGAKCDQCKPNHYGLSATDPLG-CQPCDCNPLGSLPFLTCDVDTGQCL-CLSYVTGAHC 486
Query: 107 ERCQEGYYG--NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164
E C GY+G N +HG C C C +++ C G +C C+ TG C APGY
Sbjct: 487 EECTVGYWGLGNHLHG-CSPCDCDIGGAYSNVCSPKNG--QCECRPHVTGRSCSEPAPGY 543
Query: 165 FGNPQKF 171
F P F
Sbjct: 544 FFAPLNF 550
Score = 46.6 bits (109), Expect = 2e-04
Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 6/80 (7%)
Query: 118 VHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQP 177
+H AC C S + C GG +C CK G C+RC+ G + C P
Sbjct: 762 LHDGAVACKCHPQGSVGSSCSRLGG--QCQCKPLVVGRCCDRCSTGSYDLGHH---GCHP 816
Query: 178 CSCNSNGQLGS-CHPLTGDC 196
C C+ G + C +TG C
Sbjct: 817 CHCHPQGSKDTVCDQVTGQC 836
Score = 35.4 bits (80), Expect = 0.48
Identities = 25/113 (22%), Positives = 55/113 (48%), Gaps = 1/113 (0%)
Query: 230 QLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDL 289
Q R +KS+L+ +GL + + ++T+ + ++ +N + + + LE+E +L
Sbjct: 1610 QTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVEL 1669
Query: 290 NQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQI 342
+++ LQ K +TL V + +A++L + IR + L ++I
Sbjct: 1670 KKQYAILQRKTSTTGLTKETL-GKVKQLKDAAEKLAGDTEAKIRRITDLERKI 1721
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 126 bits (317), Expect = 2e-28
Identities = 174/779 (22%), Positives = 319/779 (40%), Gaps = 103/779 (13%)
Query: 25 CLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHS 84
C Y + +Q+ GQ + +V + C PG+Y G RC C+ G +
Sbjct: 886 CNLYGTMKQQSSCNPVTGQCEC-LPHVTGQDCGACDPGFYNLQSGQGCERC-DCHALGST 943
Query: 85 N-QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGD 143
N QC +G C CQ G+HCERC+ ++G G C+ C C S + C +G
Sbjct: 944 NGQCDIRTGQC-ECQPGITGQHCERCEVNHFGFGPEG-CKPCDCHPEGSLSLQCKDDG-- 999
Query: 144 VRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 203
RC C+ G+ G +C++C YF N G CQ C +C+ L D K
Sbjct: 1000 -RCECREGFVGNRCDQCEENYFYNRSWPG--CQECP--------ACYRLVKD------KV 1042
Query: 204 SSPAEECDDCDSCVMTLLNDLATMGEQL---RLVKSQLQGLSASAGLLEQMRHMETQAKD 260
+ + + +S + L + +Q RL +++ + + LL + + ++ ++
Sbjct: 1043 ADHRVKLQELESLIANLGTGDEMVTDQAFEDRLKEAEREVMD----LLREAQDVKDVDQN 1098
Query: 261 LRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQS 320
L ++L + +S+ S+++ + + +E L E+A+ + + L +R +
Sbjct: 1099 LMDRLQRVNNTLSSQISRLQNIRNTI----EETGNLAEQARAHVENTERLIEIASRELEK 1154
Query: 321 AKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHL 380
AK + ++ + Q T G+ NN+ AE R + E + +
Sbjct: 1155 AK---------VAAANVSVTQPEST-GDPNNMTL------LAEEARKLAERHKQEADDIV 1198
Query: 381 REAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA 440
R A+ S N + +T GEN A I + +YE + ++ L+
Sbjct: 1199 RVAKTANDTSTEAYNLL---LRTLAGENQ-TAFEIEELNRKYE-QAKNISQDLE------ 1247
Query: 441 KQANGLNQENERA---LGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQK 497
KQA +++E +RA I V +++ L S+ + A++ ++ QL+++ K
Sbjct: 1248 KQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLE--NEANNIKMEAENLEQLIDQKLK 1305
Query: 498 EYEKLAASLNEARQELSDKVRE-----------LSRSAGKTSLVEEAEKHAR-SLQELAK 545
+YE L + E+ + + + L+R+ +L EEA K R +LQE
Sbjct: 1306 DYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLARADAAKALAEEAAKKGRDTLQEAND 1365
Query: 546 QLEEIKRNASGDELVRCAVDAATAYENILNAIKA-----------AEDAANRAASASESA 594
L +K + R D TA E L I A +A SA+ A
Sbjct: 1366 ILNNLK------DFDRRVNDNKTAAEEALRKIPAINQTITEANEKTREAQQALGSAAADA 1419
Query: 595 LQTVIK-EDLPRKAKTLSSNSDKLLNEAKMTQKK---LKQEVSPALNNLQQTLNIVTVQK 650
+ K + R A + N+ EA+ T + L EV+ L LQ+ + ++
Sbjct: 1420 TEAKNKAHEAERIASAVQKNATSTKAEAERTFAEVTDLDNEVNNMLKQLQEAEKELKRKQ 1479
Query: 651 EVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQT-DVERIKD 709
+ D ++ Q +I+A AK+ V I +++L+ L + T D+ ++ +
Sbjct: 1480 DDADQDMMMAGMASQAAQEAEINA--RKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNE 1537
Query: 710 TYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELI 768
G + ++D D V+ L N+ I N+ + + N++ IR+ +
Sbjct: 1538 IEGTLNKAKDEMKVSDLDRKVSDLENEAKKQEAAIMDYNRDIEEIMKDIRNLEDIRKTL 1596
Score = 123 bits (309), Expect = 1e-27
Identities = 69/185 (37%), Positives = 95/185 (51%), Gaps = 32/185 (17%)
Query: 59 CSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA 117
C GY R+ L CV C CNGHS C +G+C NC+ NTAG HCE+C +GYYG++
Sbjct: 704 CLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAGPHCEKCSDGYYGDS 762
Query: 118 VHGS---CRACPCPHTNSFATGCVVNGGDVRC-SCKAGYTGTQCERCAPGYFGNPQKFGG 173
G+ C+ CPCP +S A V +V C +C G TG +CE C GYFG+P G
Sbjct: 763 TAGTSSDCQPCPCPGGSSCAV--VPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNG 820
Query: 174 S---CQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAEE 209
C+ C C+ N +G+C+ LTG+C+ P +PA++
Sbjct: 821 PVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADK 880
Query: 210 CDDCD 214
C C+
Sbjct: 881 CKACN 885
Score = 117 bits (292), Expect = 1e-25
Identities = 53/145 (36%), Positives = 76/145 (52%), Gaps = 15/145 (10%)
Query: 75 CVPCNCNGHSNQCQ---------DGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRAC 125
C+PC+CNG S +C G C NCQ NT G HCERC+E ++ + +C +C
Sbjct: 339 CLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSC 398
Query: 126 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ 185
C S +T C G RCSCK G G +C+RC PG+ + C+PCSC+ +G
Sbjct: 399 HCSPVGSLSTQCDSYG---RCSCKPGVMGDKCDRCQPGFHSLTE---AGCRPCSCDPSGS 452
Query: 186 LGSCHPLTGDCINQEPKDSSPAEEC 210
+ C+ TG C+ ++ + E C
Sbjct: 453 IDECNIETGRCVCKDNVEGFNCERC 477
Score = 46.2 bits (108), Expect = 3e-04
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 146 CSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 203
C+C GY G CE C GY G C C+CN + + +C P TG C ++
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSE--TCDPETGVCNCRDNTA 747
Query: 204 SSPAEECDD 212
E+C D
Sbjct: 748 GPHCEKCSD 756
Score = 32.0 bits (71), Expect = 5.3
Identities = 14/37 (37%), Positives = 18/37 (48%), Gaps = 1/37 (2%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICV 95
C PG++ G C PC C GHS+ C + G V
Sbjct: 477 CKPGFFNLESSNPRG-CTPCFCFGHSSVCTNAVGYSV 512
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 122 bits (306), Expect = 3e-27
Identities = 187/815 (22%), Positives = 329/815 (40%), Gaps = 138/815 (16%)
Query: 57 QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Q C+ GY RD L G C+PCNC G C +G C + N E C C G+Y
Sbjct: 394 QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
Query: 116 NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172
N H SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P
Sbjct: 451 NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
Query: 173 G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208
G CQPC CN+N G+C LTG C+ +P +PA+
Sbjct: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
Query: 209 ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268
+C C +C + + + K G + G Q K +Q +
Sbjct: 569 KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
Query: 269 RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN-------- 311
+ SK +G LE + Q + + AQ++ +++L
Sbjct: 627 LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
Query: 312 ---------NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD 356
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 687 QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASD 746
Query: 357 -------FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGE 407
F EA R+ N + RE E +++ L+ + H+G
Sbjct: 747 HYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGV 801
Query: 408 NNGLAN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVK 462
+G + ++ L E K L +L A QA+ +A+ Q + R L ++ R Q
Sbjct: 802 GSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGV 861
Query: 463 EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------EL 513
S Q + K + SL +++ + M++ ++ + L EA+Q E
Sbjct: 862 SDQSFQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
Query: 514 SDKV---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR--- 561
SD++ L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 920 SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLS 977
Query: 562 ----CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKL 617
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++
Sbjct: 978 YISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVT 1035
Query: 618 LNEAKMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDID 673
+ A +K LK E+ L+ +KE+ DTN+ ++ + Q+ +D
Sbjct: 1036 ADGALAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQK--VD 1085
Query: 674 AMISSAKSMVRKANDITDEVLDGLN-PIQTDVERI-----KDTYGRTQ-NEDFKKALTDA 726
+A ++ + D +L ++ P+ D E + K + +TQ N + +++
Sbjct: 1086 TRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQINSQLRPMMSEL 1145
Query: 727 DNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNM 761
+ + L L I+ I + L NI DN+
Sbjct: 1146 EERARQQRGHLHLLETSIDGILADVKNLENIRDNL 1180
Score = 98.6 bits (244), Expect = 5e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 72 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
Query: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
Query: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
C C+ G G C G C+ K + E CD C S
Sbjct: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
Score = 59.3 bits (142), Expect = 3e-08
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
+C C GY G C+ CA GY + + G G+C PC+C G+C P TGDC +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
Query: 203 DSSPAEECDDC 213
D +P EC DC
Sbjct: 435 DENPDIECADC 445
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 115 bits (288), Expect = 4e-25
Identities = 63/168 (37%), Positives = 88/168 (52%), Gaps = 17/168 (10%)
Query: 57 QGCSPGYYRDH-KGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
+ C+PGY R+ +G CVPC CN H C +GICV C H+T G CERC G+YG
Sbjct: 685 ESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEGPSCERCLPGFYG 742
Query: 116 NAVHG---SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKF 171
N G C+ CPCP ++ T + +V C+ C G G +CE C G+FG+P
Sbjct: 743 NPFAGQADDCQPCPCPGQSACTT--IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGL 800
Query: 172 GGSCQP---CSCNSN---GQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
G QP C C+ N +G+C PL+G C+ ++ + C+ C
Sbjct: 801 FGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL--RCLHNTTGDHCEHC 846
Score = 110 bits (274), Expect = 2e-23
Identities = 52/145 (35%), Positives = 73/145 (50%), Gaps = 15/145 (10%)
Query: 75 CVPCNCNGHSNQCQ---------DGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRAC 125
C+PCNC+G S +C G C +C+ +TAG HCERCQE +Y C+ C
Sbjct: 324 CLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPC 383
Query: 126 PCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQ 185
C S C G C+CK TG +C+RC PG+ + G C+PC+CN G
Sbjct: 384 DCQSAGSLHLQCDDTG---TCACKPTVTGWKCDRCLPGFHSLSE---GGCRPCTCNPAGS 437
Query: 186 LGSCHPLTGDCINQEPKDSSPAEEC 210
L +C P +G C +E + + + C
Sbjct: 438 LDTCDPRSGRCPCKENVEGNLCDRC 462
Score = 104 bits (260), Expect = 6e-22
Identities = 62/186 (33%), Positives = 83/186 (44%), Gaps = 25/186 (13%)
Query: 40 PPGQSQLQASYVEFRPSQGCSPGYYRDHKGLY--TGRCVPCNCNGHSN-----QCQDGSG 92
PPGQ R + C G++ D GL+ C C C+G+ + C SG
Sbjct: 778 PPGQRG--------RRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSG 829
Query: 93 ICVNCQHNTAGEHCERCQEGYYGNAV----HGSCRACPCPHTNSFATGCVVNGGDVRCSC 148
C+ C HNT G+HCE CQEG+YG+A+ C C C S + + +CSC
Sbjct: 830 HCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSC 889
Query: 149 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPA 207
T C RC PG+F + G C+ C C+ G Q CHP TG C +
Sbjct: 890 LPHVTARDCSRCYPGFF--DLQPGRGCRSCKCHPLGSQEDQCHPKTGQC---TCRPGVTG 944
Query: 208 EECDDC 213
+ CD C
Sbjct: 945 QACDRC 950
Score = 92.4 bits (228), Expect = 3e-18
Identities = 136/654 (20%), Positives = 241/654 (36%), Gaps = 108/654 (16%)
Query: 74 RCVPCNCNGHSN-----QCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCP 128
+C+PC+C+ + C +G C H TA + C RC G++ CR+C C
Sbjct: 862 KCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARD-CSRCYPGFFDLQPGRGCRSCKCH 920
Query: 129 HTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS 188
S C G +C+C+ G TG C+RC G+FG K C+ C C+ G +
Sbjct: 921 PLGSQEDQCHPKTG--QCTCRPGVTGQACDRCQLGFFGFSIK---GCRACRCSPLGAASA 975
Query: 189 -CHPLTGDCINQEPKDSSPAEECDD-------------CDSCVMTLLNDLATMGEQLRLV 234
CH G C+ + + + C D C SC + + A + +L L
Sbjct: 976 QCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPSCYALVKEEAAKLKARLTLT 1034
Query: 235 KSQLQGL-----------------------------SASAGLLEQMRHMETQAKDLRNQL 265
+ LQG A LEQM +E K R QL
Sbjct: 1035 EGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLLPGAREAFLEQMMSLEGAVKAAREQL 1094
Query: 266 --LNYRSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAK- 322
LN + + GS + +L DL E+ +E+ + +L +Q K
Sbjct: 1095 QRLNKGARCAQAGS--QKTCTQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKW 1152
Query: 323 -ELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLR 381
L + + + R+ +I+ T + ++ W + + R+ +
Sbjct: 1153 SHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQ 1212
Query: 382 EAEADKRESQLLLNRI--------RTWQKTHQGENNGLANSIRDSLNEYEAKLSDL---- 429
E +A ++ + + + T Q+ LA +++ DL
Sbjct: 1213 EVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKA 1272
Query: 430 RARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIAL 489
+A + A+ A + + A A RQ + + L + LT A SS+ + +
Sbjct: 1273 KALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTV 1332
Query: 490 QLME---------KSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL 540
K Q K A+L +SD++ L+ + KT E +A L
Sbjct: 1333 MGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRL--LADTRKKTKQAERMLGNAAPL 1390
Query: 541 QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIK 600
AK+ G E A D+A + +L K A A+R S +++ LQ
Sbjct: 1391 SSSAKK--------KGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQ---- 1438
Query: 601 EDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTL--NIVTVQKEV 652
++ L +EA+ + + + V L+ ++Q + + ++++K++
Sbjct: 1439 ----------QASQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDI 1482
Score = 63.5 bits (153), Expect = 2e-09
Identities = 34/86 (39%), Positives = 39/86 (45%), Gaps = 18/86 (20%)
Query: 146 CSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPKD 203
CSC GYTG CE CAPGY + G SC PC+CN Q G+C P TG C+ +
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCN---QHGTCDPNTGICVCSHHTE 729
Query: 204 SSPAEEC-------------DDCDSC 216
E C DDC C
Sbjct: 730 GPSCERCLPGFYGNPFAGQADDCQPC 755
Score = 58.9 bits (141), Expect = 4e-08
Identities = 42/129 (32%), Positives = 51/129 (39%), Gaps = 17/129 (13%)
Query: 93 ICVNCQHNTAGEHCERCQEGYYGNAVHG----SCRACPCPHTNSFATGCVVNGGDVRCSC 148
IC +C G+ CE C GY G SC C C N T C N G C C
Sbjct: 672 IC-SCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTC---NQHGT-CDPNTG--ICVC 724
Query: 149 KAGYTGTQCERCAPGYFGNPQKFGG---SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSS 205
G CERC PG++GNP F G CQPC C + P + + +
Sbjct: 725 SHHTEGPSCERCLPGFYGNP--FAGQADDCQPCPCPGQSACTTI-PESREVVCTHCPPGQ 781
Query: 206 PAEECDDCD 214
C+ CD
Sbjct: 782 RGRRCEVCD 790
Score = 47.8 bits (112), Expect = 9e-05
Identities = 26/73 (35%), Positives = 34/73 (46%), Gaps = 9/73 (12%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGN 116
C PG++ L G C PC CN G + C SG C C+ N G C+RC+ G +
Sbjct: 415 CLPGFH----SLSEGGCRPCTCNPAGSLDTCDPRSGRC-PCKENVEGNLCDRCRPGTFNL 469
Query: 117 AVH--GSCRACPC 127
H C +C C
Sbjct: 470 QPHNPAGCSSCFC 482
Score = 43.1 bits (100), Expect = 0.002
Identities = 33/124 (26%), Positives = 45/124 (36%), Gaps = 32/124 (25%)
Query: 110 QEGYYGNAVHGSCRACPCPHTNSFATGCVVN-GGDVRCSCKAGYTGTQCERCAPGYFGNP 168
Q YY + C C N A+ C + G + C C+ TGT CERC P + P
Sbjct: 256 QSYYYAVSDFSVGGRCKC---NGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRP 312
Query: 169 QKFGGS-----CQPCSCN--------------SNGQLGSCHPLTGDCINQEPKDSSPAEE 209
G + C PC+C+ S G G CH +D +
Sbjct: 313 WARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCH---------HCRDHTAGPH 363
Query: 210 CDDC 213
C+ C
Sbjct: 364 CERC 367
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 114 bits (286), Expect = 6e-25
Identities = 169/721 (23%), Positives = 290/721 (40%), Gaps = 129/721 (17%)
Query: 57 QGCSPGYYRDHKGLYT-GRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG 115
Q C+ GY RD L G C+PCNC G C +G C + N E C C G+Y
Sbjct: 394 QDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYSGDENPDIE-CADCPIGFY- 450
Query: 116 NAVHG--SCRACPCPHTNSFATGCVVNGGDVRCS-CKAGYTGTQCERCAPGYFGNPQKFG 172
N H SC+ CPC N F+ + +V C+ C G TG +CE CA GYFG+P
Sbjct: 451 NDPHDPRSCKPCPCH--NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEH 508
Query: 173 G---SCQPCSCNSN---GQLGSCHPLTGDCIN------------------QEPKDSSPAE 208
G CQPC CN+N G+C LTG C+ +P +PA+
Sbjct: 509 GPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPAD 568
Query: 209 ECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 268
+C C +C + + + K G + G Q K +Q +
Sbjct: 569 KCRAC-NCNPMGSEPVGCRSDGTCVCKPGFGGPNCEHGAF-SCPACYNQVKIQMDQFMQQ 626
Query: 269 RSAISNHGSKIEG---------LERELTDLNQEFETLQEKAQVNSRKAQTLN-------- 311
+ SK +G LE + Q + + AQ++ +++L
Sbjct: 627 LQRMEALISKAQGGDGVVPDTELEGRMQQAEQALQDILRDAQISEGASRSLGLQLAKVRS 686
Query: 312 ---------NNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGE-----GN-NVPSGD 356
+++ + + L + +N +R+ H L+ Q+ + E GN N+P+ D
Sbjct: 687 QENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAESEASLGNTNIPASD 746
Query: 357 -------FSREWAEAQRMMRE--LRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGE 407
F EA R+ N + RE E +++ L+ + H+G
Sbjct: 747 HYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRK-----ALHEGV 801
Query: 408 NNGLAN---SIRDSLNEYEAKLSDLRARLQEAAAQAK-QANGLNQENERALGAIQR-QVK 462
+G + ++ L E K L +L A QA+ +A+ Q + R L ++ R Q
Sbjct: 802 GSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVSRLQGV 861
Query: 463 EINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQ---------EL 513
S Q + K + SL +++ + M++ ++ + L EA+Q E
Sbjct: 862 SDQSFQVEEAKRIKQKADSL--SSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREK 919
Query: 514 SDKV---RELSRSAGKTSL------VEEAEKHARSLQELAKQLEEIKRNASGDELVR--- 561
SD++ L++S + +L E E ++L+E Q++ R A +E ++
Sbjct: 920 SDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVD--NRKAEAEEAMKRLS 977
Query: 562 ----CAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKL 617
DA+ + A+ +A A RA + + AL+ I ++ ++ +L+ ++
Sbjct: 978 YISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALE--ISSEIEQEIGSLNLEANVT 1035
Query: 618 LNEAKMTQK---KLKQEVSPALNNLQQTLNIVTVQKEV-IDTNLTTLRDGLHGIQRGDID 673
+ A +K LK E+ L+ +KE+ DTN+ ++ + Q+ D
Sbjct: 1036 ADGALAMEKGLASLKSEMREVEGELE--------RKELEFDTNMDAVQMVITEAQKVDTR 1087
Query: 674 A 674
A
Sbjct: 1088 A 1088
Score = 98.6 bits (244), Expect = 5e-20
Identities = 58/158 (36%), Positives = 73/158 (46%), Gaps = 22/158 (13%)
Query: 72 TGRCVPCNCNGHSNQC--------QDGSGI-CVNCQHNTAGEHCERCQEGYYGNAVHGSC 122
T R C+CNG S QC Q G+G C+NC NT G HCE+C+ G+Y + C
Sbjct: 22 TSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRC 81
Query: 123 RACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYF-----GNPQKFGGSCQP 177
C C S + C +G RCSCK G TG +C+RC PG+ G Q
Sbjct: 82 LPCNCNSKGSLSARCDNSG---RCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSK 138
Query: 178 CSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
C C+ G G C G C+ K + E CD C S
Sbjct: 139 CDCDPAGIAGPCD--AGRCV---CKPAVTGERCDRCRS 171
Score = 59.3 bits (142), Expect = 3e-08
Identities = 29/71 (40%), Positives = 38/71 (53%), Gaps = 8/71 (11%)
Query: 145 RCSCKAGYTGTQCERCAPGYFGNPQKFG--GSCQPCSCNSNGQLGSCHPLTGDCINQEPK 202
+C C GY G C+ CA GY + + G G+C PC+C G+C P TGDC +
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG---GACDPDTGDCYS---G 434
Query: 203 DSSPAEECDDC 213
D +P EC DC
Sbjct: 435 DENPDIECADC 445
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 105 bits (261), Expect = 5e-22
Identities = 60/171 (35%), Positives = 81/171 (47%), Gaps = 40/171 (23%)
Query: 57 QGCSPGYY------RDHKGLYTGRCVPCNCNGHSNQCQ-----------DGSGICVNCQH 99
Q C+P Y D K C C CNGH++ C G+C +CQH
Sbjct: 305 QHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQH 364
Query: 100 NTAGEHCERCQEGYYGN-----AVHGSCRACPCPHTNS------FATGCVVNGGDVRCSC 148
NT G++C+RC+ G+Y + + +C+ C C S T C + GD C C
Sbjct: 365 NTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGD--CPC 422
Query: 149 KAGYTGTQCERCAPGYFGNPQKFGG-SCQPCSCNSNGQLGSCHPLTGDCIN 198
K G G +C+RC GY+G FG C+PC C GSC P+TGDCI+
Sbjct: 423 KPGVAGRRCDRCMVGYWG----FGDYGCRPCDC-----AGSCDPITGDCIS 464
Score = 70.9 bits (172), Expect = 1e-11
Identities = 51/180 (28%), Positives = 66/180 (36%), Gaps = 51/180 (28%)
Query: 78 CNCNGHSNQCQDGSGI---------------CVNCQHNTAGEHCERCQEGYYG------- 115
C CNGH++QC G C+ C+HNTAG HC+ C Y
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 116 --NAVHGSCRACPCPHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPG 163
CR C C N A C + G V C+ G C+RC PG
Sbjct: 321 GKTGAPNECRTCKC---NGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPG 377
Query: 164 YFGN---PQKFGGSCQPCSCNSNG-------QLGSCHPLTGDCINQEPKDSSPAEECDDC 213
++ + P +C+PCSC+ G + C P GDC K CD C
Sbjct: 378 FYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDC---PCKPGVAGRRCDRC 434
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 102 bits (254), Expect = 3e-21
Identities = 52/148 (35%), Positives = 70/148 (47%), Gaps = 17/148 (11%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA- 117
C GYY G C+PC CN S C +G C+NCQ N+ G HCE C+EG+Y +
Sbjct: 323 CQDGYY----GFSKNGCLPCQCNNRSASCDALTGACLNCQENSKGNHCEECKEGFYQSPD 378
Query: 118 VHGSCRACPCPHTNSFATGCVVNGGDV--RC-SCKAGYTGTQCERCAPGYFGNPQKFGGS 174
C CPC S + C + ++ C CK GY G C +C GY+ F
Sbjct: 379 ATKECLRCPCSAVTSTGS-CSIKSSELEPECDQCKDGYIGPNCNKCENGYY----NFDSI 433
Query: 175 CQPCSCNSNGQLGS----CHPLTGDCIN 198
C+ C C+ + C P +G+CIN
Sbjct: 434 CRKCQCHGHVDPVKTPKICKPESGECIN 461
Score = 98.2 bits (243), Expect = 6e-20
Identities = 51/140 (36%), Positives = 71/140 (50%), Gaps = 14/140 (10%)
Query: 78 CNCNG----HSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSF 133
CNC+ + N+C +G C C+ G HCE C+EG+Y N G C+ C C +
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGAL 299
Query: 134 ATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLT 193
+ C +G +C CK G G+ C+RC GY+G + C PC CN+ SC LT
Sbjct: 300 SIPCNSSG---KCQCKVGVIGSICDRCQDGYYGFSK---NGCLPCQCNNRS--ASCDALT 351
Query: 194 GDCIN-QEPKDSSPAEECDD 212
G C+N QE + EEC +
Sbjct: 352 GACLNCQENSKGNHCEECKE 371
Score = 54.7 bits (130), Expect = 8e-07
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 12/70 (17%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ------CQDGSGICVNCQHNTAGEHCERCQEG 112
C GYY + C C C+GH + C+ SG C+NC HNT G CE C EG
Sbjct: 423 CENGYYN-----FDSICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTGFWCENCLEG 477
Query: 113 YYGNAVHGSC 122
Y + + G+C
Sbjct: 478 YV-HDLEGNC 486
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 97.4 bits (241), Expect = 1e-19
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 33/196 (16%)
Query: 47 QASYVEFRPSQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC--------------Q 88
Q S+ E C P Y +R +Y C PC CN HS C +
Sbjct: 540 QESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR 599
Query: 89 DGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCVVNG 141
G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C G
Sbjct: 600 GGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIG 659
Query: 142 GDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGDCIN 198
G +C+CK +G QC +C G++ + C PC+CN++G + +CH +G C
Sbjct: 660 G--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-- 715
Query: 199 QEPKDSSPAEECDDCD 214
+ K + CD C+
Sbjct: 716 -KCKANVIGLRCDHCN 730
Score = 83.2 bits (204), Expect = 2e-15
Identities = 52/164 (31%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 39 QPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICV 95
Q GQ + +A+ + R C+ G+ + + C PC CN H + C SG C
Sbjct: 710 QNSGQCKCKANVIGLRCDH-CNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC- 766
Query: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 155
C+ G C+ C+E +YG V +C+AC C S G V N +C CK G
Sbjct: 767 ECKKEAKGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGR 824
Query: 156 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 196
QC +C G F Q C PC+C+ G + C+ TG C
Sbjct: 825 QCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868
Score = 80.5 bits (197), Expect = 1e-14
Identities = 77/335 (22%), Positives = 140/335 (41%), Gaps = 40/335 (11%)
Query: 1420 GTKNSFMALYLSKGRLVFALGTDGKKLRIKSK----EKCNDGKWHTVVFGHDGEKGRLVV 1475
G + + AL L KGRL F G + + + ++ +DGKWH ++ G++ +
Sbjct: 1564 GNQEEYFALQLKKGRLYFLFDPQGSPVEVTTTNDHGKQYSDGKWHEIIAIRHQAFGQITL 1623
Query: 1476 DGLRAREGS-LPGNSTISIRAPVYLGSPPSG-----KPKSLPTNSFVGCLKNFQLDSKPL 1529
DG+ + L G++ I V+LG P K + FVGCLK+
Sbjct: 1624 DGIYTGSSAILNGSTVIGDNTGVFLGGLPRSYTILRKDPEIIQKGFVGCLKDVHFMKN-- 1681
Query: 1530 YTPSSSFGVSSCLGGPLEKGIYFSEEGG------------------HVVLAHSVLLGPEF 1571
Y PS+ + + +Y S EG H + H G F
Sbjct: 1682 YNPSAIWEPLDWQSSEEQINVYNSWEGCPASLNEGAQFLGAGFLELHPYMFHG---GMNF 1738
Query: 1572 KLVFSIRPRSLTGILIHIGSQPG-KHLCVYLEAGKVTASMDSGAGGTSTSVTPKQSLCDG 1630
++ F R L G+L+ + ++ G L + L++G +T +++ T + S C+G
Sbjct: 1739 EISFKFRTDQLNGLLLFVYNKDGPDFLAMELKSGILTFRLNTSLAFTQVDLLLGLSYCNG 1798
Query: 1631 QWHSVAVTIKQHILHLELDTDSSYTAGQIPFPPASTQEPLHLGGAPANL--TTLRIPVWK 1688
+W+ V + + + ++ + A + P P+++GG P L + + + +
Sbjct: 1799 KWNKVIIKKEGSFISASVNGLMKH-ASESGDQPLVVNSPVYVGGIPQELLNSYQHLCLEQ 1857
Query: 1689 SFFGCLRNIHVNHIPVPVTEALEVQGP--VSLNGC 1721
F GC++++ V V A G V+L+GC
Sbjct: 1858 GFGGCMKDVKFTRGAV-VNLASVSSGAVRVNLDGC 1891
Score = 79.0 bits (193), Expect = 4e-14
Identities = 54/153 (35%), Positives = 73/153 (47%), Gaps = 23/153 (15%)
Query: 75 CVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQEGYY---GNAVHGSCRACPC 127
C C C+ C SG C+ C N G C +CQ G+Y GNA C C C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISPGNAT--GCLPCSC 953
Query: 128 PHTNSFATGCVVNGGDVRCSCK-AGYTGTQCERCAPGYFG-NPQKFGGSCQPCSCNSNGQ 185
HT A + N +C C+ A G +C++C YFG +PQ G CQPC+C+ +G
Sbjct: 954 -HTTG-AVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQT--GRCQPCNCHLSGA 1009
Query: 186 LG-SCHPLTGDCINQEPKDSSPAEECDDCDSCV 217
L +CH +TG C ++ S CD+CV
Sbjct: 1010 LNETCHLVTGQCFCKQFVTGS------KCDACV 1036
Score = 78.2 bits (191), Expect = 7e-14
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 18/173 (10%)
Query: 51 VEFRPSQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNCQHNTAG 103
VE R C G Y R + C+PCNC+ S C +G C C+ G
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTG 876
Query: 104 EHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 161
C +C+ Y + C+ C C + G + + +C C G +C +C
Sbjct: 877 LRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRCNQCQ 935
Query: 162 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C
Sbjct: 936 PGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985
Score = 77.0 bits (188), Expect = 1e-13
Identities = 47/150 (31%), Positives = 67/150 (44%), Gaps = 18/150 (12%)
Query: 75 CVPCNCN-----GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPC 127
C PC+C+ S C G C NC+ + +G C +CQ G+Y C C C
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC 696
Query: 128 PHTNSFATG---CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG 184
+T+ G C N G +C CKA G +C+ C G+ C+PC CN +G
Sbjct: 697 -NTSGTVDGDITCHQNSG--QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 185 QLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
+ C+P +G C E K + +CD C
Sbjct: 754 SVNKFCNPHSGQC---ECKKEAKGLQCDTC 780
Score = 75.1 bits (183), Expect = 6e-13
Identities = 44/160 (27%), Positives = 66/160 (41%), Gaps = 13/160 (8%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQEGYY 114
C +Y GL C C+C+ + C +G C+ C+ N G C +C EG +
Sbjct: 780 CRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNF 834
Query: 115 GNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
+ S C C C T + + N +C CK G TG +C +C P +
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNF 894
Query: 173 GSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 210
CQ C C+S G L C P++G C+ + +C
Sbjct: 895 QHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 65.1 bits (157), Expect = 6e-10
Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 8/108 (7%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C PG+Y G TG C+PC+C+ G N C +G CV + AG+ C++C++ Y+G
Sbjct: 934 CQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 116 -NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 162
+ G C+ C C + + C + G +C CK TG++C+ C P
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDACVP 1037
Score = 58.2 bits (139), Expect = 7e-08
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 113
YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y
Sbjct: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 114 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 159
G+ V+ +C+ C C NS + C N GG V C+ TG CE
Sbjct: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619
Query: 160 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 213
C +F G C+PC C++ G C + G C K +C+ C
Sbjct: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676
Query: 214 DS 215
+
Sbjct: 677 QN 678
Score = 32.3 bits (72), Expect = 4.1
Identities = 34/129 (26%), Positives = 61/129 (47%), Gaps = 19/129 (14%)
Query: 1024 GLLFFAEN--GDRFISLNIEDGKLMVRYKLNSELPKERG---VGDAINNGRDHSIQIKIG 1078
GLL F N G F+++ ++ G ++ ++LN+ L + +G + NG+ + + IK
Sbjct: 1751 GLLLFVYNKDGPDFLAMELKSG--ILTFRLNTSLAFTQVDLLLGLSYCNGKWNKVIIK-- 1806
Query: 1079 KLQKRMWINVDVQNTII------DGEVFDFSTYYLGGIPIAIRERFN--ISTPAFRGCMK 1130
++ +I+ V + D + S Y+GGIP + + F GCMK
Sbjct: 1807 --KEGSFISASVNGLMKHASESGDQPLVVNSPVYVGGIPQELLNSYQHLCLEQGFGGCMK 1864
Query: 1131 NLKKTSGVV 1139
++K T G V
Sbjct: 1865 DVKFTRGAV 1873
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 97.4 bits (241), Expect = 1e-19
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 33/196 (16%)
Query: 47 QASYVEFRPSQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQC--------------Q 88
Q S+ E C P Y +R +Y C PC CN HS C +
Sbjct: 540 QESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFR 599
Query: 89 DGSGICVNCQHNTAGEHCERCQEGYYGN-----AVHGSCRACPCPH--TNSFATGCVVNG 141
G G+C +C+HNT G +CE C++ ++ + C+ C C T + + C G
Sbjct: 600 GGGGVCDDCEHNTTGRNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIG 659
Query: 142 GDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG---SCHPLTGDCIN 198
G +C+CK +G QC +C G++ + C PC+CN++G + +CH +G C
Sbjct: 660 G--QCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQC-- 715
Query: 199 QEPKDSSPAEECDDCD 214
+ K + CD C+
Sbjct: 716 -KCKANVIGLRCDHCN 730
Score = 83.2 bits (204), Expect = 2e-15
Identities = 52/164 (31%), Positives = 73/164 (44%), Gaps = 11/164 (6%)
Query: 39 QPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---CQDGSGICV 95
Q GQ + +A+ + R C+ G+ + + C PC CN H + C SG C
Sbjct: 710 QNSGQCKCKANVIGLRCDH-CNFGF-KFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQC- 766
Query: 96 NCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGT 155
C+ G C+ C+E +YG V +C+AC C S G V N +C CK G
Sbjct: 767 ECKKEAKGLQCDTCRENFYGLDVT-NCKACDCDTAGSLP-GTVCNAKTGQCICKPNVEGR 824
Query: 156 QCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDC 196
QC +C G F Q C PC+C+ G + C+ TG C
Sbjct: 825 QCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQC 868
Score = 79.0 bits (193), Expect = 4e-14
Identities = 54/153 (35%), Positives = 73/153 (47%), Gaps = 23/153 (15%)
Query: 75 CVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQEGYY---GNAVHGSCRACPC 127
C C C+ C SG C+ C N G C +CQ G+Y GNA C C C
Sbjct: 897 CQMCECDSLGTLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISPGNAT--GCLPCSC 953
Query: 128 PHTNSFATGCVVNGGDVRCSCK-AGYTGTQCERCAPGYFG-NPQKFGGSCQPCSCNSNGQ 185
HT A + N +C C+ A G +C++C YFG +PQ G CQPC+C+ +G
Sbjct: 954 -HTTG-AVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQT--GRCQPCNCHLSGA 1009
Query: 186 LG-SCHPLTGDCINQEPKDSSPAEECDDCDSCV 217
L +CH +TG C ++ S CD+CV
Sbjct: 1010 LNETCHLVTGQCFCKQFVTGS------KCDACV 1036
Score = 78.2 bits (191), Expect = 7e-14
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 18/173 (10%)
Query: 51 VEFRPSQGCSPG--YYRDHKGLYTGRCVPCNCN-----GHSNQCQDGSGICVNCQHNTAG 103
VE R C G Y R + C+PCNC+ S C +G C C+ G
Sbjct: 821 VEGRQCNKCLEGNFYLRQNNSFL---CLPCNCDKTGTINGSLLCNKSTGQCP-CKLGVTG 876
Query: 104 EHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCA 161
C +C+ Y + C+ C C + G + + +C C G +C +C
Sbjct: 877 LRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP-GTICDPISGQCLCVPNRQGRRCNQCQ 935
Query: 162 PGYFGNPQKFGGSCQPCSCNSNGQLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
PG++ +P G C PCSC++ G + C+ LTG C+ Q+ S + CD C
Sbjct: 936 PGFYISPGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDA--SIAGQRCDQC 985
Score = 77.0 bits (188), Expect = 1e-13
Identities = 47/150 (31%), Positives = 67/150 (44%), Gaps = 18/150 (12%)
Query: 75 CVPCNCN-----GHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYG--NAVHGSCRACPC 127
C PC+C+ S C G C NC+ + +G C +CQ G+Y C C C
Sbjct: 638 CKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNC 696
Query: 128 PHTNSFATG---CVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNG 184
+T+ G C N G +C CKA G +C+ C G+ C+PC CN +G
Sbjct: 697 -NTSGTVDGDITCHQNSG--QCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHG 753
Query: 185 QLGS-CHPLTGDCINQEPKDSSPAEECDDC 213
+ C+P +G C E K + +CD C
Sbjct: 754 SVNKFCNPHSGQC---ECKKEAKGLQCDTC 780
Score = 75.1 bits (183), Expect = 6e-13
Identities = 44/160 (27%), Positives = 66/160 (41%), Gaps = 13/160 (8%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQEGYY 114
C +Y GL C C+C+ + C +G C+ C+ N G C +C EG +
Sbjct: 780 CRENFY----GLDVTNCKACDCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNF 834
Query: 115 GNAVHGS--CRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFG 172
+ S C C C T + + N +C CK G TG +C +C P +
Sbjct: 835 YLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNF 894
Query: 173 GSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEEC 210
CQ C C+S G L C P++G C+ + +C
Sbjct: 895 QHCQMCECDSLGTLPGTICDPISGQCLCVPNRQGRRCNQC 934
Score = 65.1 bits (157), Expect = 6e-10
Identities = 37/108 (34%), Positives = 58/108 (53%), Gaps = 8/108 (7%)
Query: 59 CSPGYYRDHKGLYTGRCVPCNCN--GHSNQ-CQDGSGICVNCQHNTAGEHCERCQEGYYG 115
C PG+Y G TG C+PC+C+ G N C +G CV + AG+ C++C++ Y+G
Sbjct: 934 CQPGFYIS-PGNATG-CLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCDQCKDHYFG 991
Query: 116 -NAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAP 162
+ G C+ C C + + C + G +C CK TG++C+ C P
Sbjct: 992 FDPQTGRCQPCNCHLSGALNETCHLVTG--QCFCKQFVTGSKCDACVP 1037
Score = 58.2 bits (139), Expect = 7e-08
Identities = 50/182 (27%), Positives = 72/182 (39%), Gaps = 38/182 (20%)
Query: 63 YYRDHKGLYTGRCVPCNCNGHSNQCQDGSG--ICVNCQHN-TAGEHCERCQEGY------ 113
YY + +GRC C+GH++ C S C+ Q + T G HC+RC Y
Sbjct: 506 YYAVDEITISGRC---QCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFR 562
Query: 114 YGNAVHG-SCRACPCPHTNSFATGCVVN-------------GGDVRCSCKAGYTGTQCER 159
G+ V+ +C+ C C NS + C N GG V C+ TG CE
Sbjct: 563 QGDQVYAFNCKPCQC---NSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCEL 619
Query: 160 CAPGYF---GNPQKFGGSCQPCSCNSNGQLGS---CHPLTGDCINQEPKDSSPAEECDDC 213
C +F G C+PC C++ G C + G C K +C+ C
Sbjct: 620 CKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC---NCKRHVSGRQCNQC 676
Query: 214 DS 215
+
Sbjct: 677 QN 678
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 95.5 bits (236), Expect = 4e-19
Identities = 57/157 (36%), Positives = 75/157 (47%), Gaps = 37/157 (23%)
Query: 75 CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAGEHCERCQEGYY---GNAV-- 118
C+ C+CNGH+ +C+ G+C+NC+HNTAG HC C+EG+Y G A+
Sbjct: 308 CLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSD 367
Query: 119 HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPC 178
+CRAC C A G N +C CK G TG C RCAPG+ Q+ PC
Sbjct: 368 RRACRACDCHPVG--AAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF----QQSRSPVAPC 421
Query: 179 SCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
P+ G +DSSP + DCDS
Sbjct: 422 VKT---------PIPG-----PTEDSSPVQP-QDCDS 443
Score = 65.9 bits (159), Expect = 3e-10
Identities = 45/157 (28%), Positives = 64/157 (40%), Gaps = 25/157 (15%)
Query: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGY----YGNAVHGSCRACPCPHT 130
C CNGH+++C G IC +C+H T G C RC+ Y + A AC
Sbjct: 255 CKCNGHASRCLLDTQGHLIC-DCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSC 313
Query: 131 NSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYFGNPQKF---GGSCQP 177
N A C N G V +C+ G C C G++ +P + +C+
Sbjct: 314 NGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRA 373
Query: 178 CSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213
C C+ G G +C+ TG C KD C+ C
Sbjct: 374 CDCHPVGAAGKTCNQTTGQC---PCKDGVTGLTCNRC 407
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 94.0 bits (232), Expect = 1e-18
Identities = 61/177 (34%), Positives = 78/177 (44%), Gaps = 40/177 (22%)
Query: 59 CSPGYYRDHKGLYTGR----CVPCNCNGHSNQCQ-----------DGSGICVNCQHNTAG 103
C P +Y T R CV CNCN H+ +C+ G+C+NC+HNTAG
Sbjct: 318 CKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAG 377
Query: 104 EHCERCQEGYY---GNAV--HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
HC C+EGYY G + +C+AC C A G N +C CK G TG C
Sbjct: 378 RHCHYCKEGYYRDMGKPITHRKACKACDCHPVG--AAGKTCNQTTGQCPCKDGVTGITCN 435
Query: 159 RCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDS 215
RCA GY Q+ PC ++ P T +S EE +DCDS
Sbjct: 436 RCAKGY----QQSRSPIAPCI-----KIPVAPPTTA---------ASSVEEPEDCDS 474
Score = 75.9 bits (185), Expect = 3e-13
Identities = 50/160 (31%), Positives = 68/160 (42%), Gaps = 31/160 (19%)
Query: 78 CNCNGHSNQC---QDGSGICVNCQHNTAGEHCERCQEGYYGNAVH-------GSCRACPC 127
C CNGH+ +C +D S +C +C+HNTAG C+RC+ +Y C AC C
Sbjct: 285 CKCNGHAARCVRDRDDSLVC-DCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNC 343
Query: 128 PHTNSFATGCVVN----------GGDVRCSCKAGYTGTQCERCAPGYF---GNPQKFGGS 174
N A C N G V +C+ G C C GY+ G P +
Sbjct: 344 ---NLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKA 400
Query: 175 CQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECDDC 213
C+ C C+ G G +C+ TG C KD C+ C
Sbjct: 401 CKACDCHPVGAAGKTCNQTTGQC---PCKDGVTGITCNRC 437
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 88.2 bits (217), Expect = 6e-17
Identities = 56/153 (36%), Positives = 70/153 (45%), Gaps = 32/153 (20%)
Query: 60 SPGYYRDHKGLYTGRCVP-------CNCNGHSNQCQD----GSGICVNCQHNTAGEHCER 108
SPG Y C+P C C GHSN+C + ICV+C+HNT G+HCE
Sbjct: 339 SPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCEL 398
Query: 109 CQEGYYGNAV-----HGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 163
C+ GY+ NA C C C S C G C CK G TG +C+ C P
Sbjct: 399 CRLGYFRNASAQLDDENVCIECYCNPLGSIHDRC---NGSGFCECKTGTTGPKCDECLP- 454
Query: 164 YFGNPQKFGGSCQPCSCNS------NGQLGSCH 190
GN +G CQP C++ NG G+CH
Sbjct: 455 --GNSWHYG--CQPNVCDNELLHCQNG--GTCH 481
Score = 63.9 bits (154), Expect = 1e-09
Identities = 49/159 (30%), Positives = 59/159 (37%), Gaps = 26/159 (16%)
Query: 78 CNCNGHSNQC-QDGSGICVNCQHNTAGEHCERCQEGYYGNA-VHGSCRACP------CPH 129
C CN H+ C D S + C+HNT G C +C++ Y G GS P C
Sbjct: 297 CKCNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIP 356
Query: 130 TNSFATGCVVNGGDVRC------------SCKAGYTGTQCERCAPGYFGNPQ---KFGGS 174
+ S C G RC SCK G CE C GYF N
Sbjct: 357 SISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENV 416
Query: 175 CQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 213
C C CN LGS H E K + +CD+C
Sbjct: 417 CIECYCN---PLGSIHDRCNGSGFCECKTGTTGPKCDEC 452
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 87.4 bits (215), Expect = 1e-16
Identities = 41/106 (38%), Positives = 55/106 (51%), Gaps = 18/106 (16%)
Query: 75 CVPCNCNGHSNQCQDGS-----------GICVNCQHNTAGEHCERCQEGYYGNAVHG--- 120
C+PC+CN H+ +C+ S G+C C+H+TAG HC CQ G++ +
Sbjct: 209 CLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFS 268
Query: 121 --SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGY 164
+CRAC C ATG N +C+CK G TG C RC PGY
Sbjct: 269 RRACRACQCHPIG--ATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 53.9 bits (128), Expect = 1e-06
Identities = 51/189 (26%), Positives = 77/189 (40%), Gaps = 38/189 (20%)
Query: 33 QRVPFLQPPG-QSQLQASY--VEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQD 89
+RV F PG ++ + AS+ VEF G + R GRC C+GH+ +C
Sbjct: 119 ERVTFHSTPGPKATVAASHLRVEFGGQAGLAAAGLR-------GRC---QCHGHAARCAA 168
Query: 90 GSGIC-VNCQHNTAGEHCERCQEGYY------GNAVH-GSCRACPCPHTNSFATGCVVN- 140
+ +C+H+T G CE C+ + H C C C N A C N
Sbjct: 169 RARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC---NQHARRCRFNS 225
Query: 141 ---------GGDVRCSCKAGYTGTQCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL-G 187
G V C+ G C C PG++ +P + +C+ C C+ G G
Sbjct: 226 ELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGG 285
Query: 188 SCHPLTGDC 196
+C+ +G C
Sbjct: 286 TCNQTSGQC 294
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 85.9 bits (211), Expect = 3e-16
Identities = 122/634 (19%), Positives = 269/634 (42%), Gaps = 73/634 (11%)
Query: 221 LND--LATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS-NHGS 277
LND L ++ R ++ LQ + + ++++ +H+E + K Q++ RS + H
Sbjct: 1256 LNDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELK----QVMQQRSEDNARHKQ 1311
Query: 278 KIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIR---- 333
+E + + D N+E E L+ + Q +++ N +++ + E + +KN
Sbjct: 1312 SLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEIN 1371
Query: 334 ----NVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRN--RNFGKHLREAEADK 387
+H L Q D G + +RE ++ L+N ++LR E D
Sbjct: 1372 ITKTTIHQLTMQ-KEEDTSGYRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDI 1430
Query: 388 RESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLN 447
++ + + + ++ + E + + Y+ L D +Q+ + ++ L
Sbjct: 1431 QQQKATGSEVSQRKQQLEVELRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQLI 1490
Query: 448 QENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAA--- 504
+ ++ + + +Q D K ++A ++ + + Q + + + +YE+++
Sbjct: 1491 DKETNDRKCLEDENARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERT 1550
Query: 505 -----------SLNE---ARQELSDKVRELSRSAGKTS-----LVEEAEKHARSLQE--- 542
SL E +Q++ +++ L R+A + S L EE E RSL+E
Sbjct: 1551 VKDQDITRFQNSLKELQLQKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKEQAI 1610
Query: 543 ----LAKQLEE--IKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ 596
L +QLE+ I + S D+L + + L + ++ R +S E+ +
Sbjct: 1611 KITNLTQQLEQASIVKKRSEDDLRQ----QRDVLDGHLREKQRTQEELRRLSSEVEALRR 1666
Query: 597 TVIKE-DLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDT 655
+++E + ++A + + K + + + + K E+ LQ +T + +++
Sbjct: 1667 QLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEI----ERLQSLTENLTKEHLMLEE 1722
Query: 656 NLTTLRDGLHGIQRG------DIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKD 709
L LR ++RG D +A I +S ++ +N+ T E+ +N +Q + E +
Sbjct: 1723 ELRNLRLEYDDLRRGRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENL-- 1780
Query: 710 TYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQ 769
R + E F+K +A N + + N+ + ++ ES+ L+ + + + R++ L
Sbjct: 1781 ---RQEIEKFQKQALEASNRIQESKNQCTQVVQERESL---LVKIKVLEQDKARLQRLED 1834
Query: 770 QARDAASKVAVPMRFNGKSGVE-VRLPNDLEDLK 802
+ A S + R + E ++ NDL K
Sbjct: 1835 ELNRAKSTLEAETRVKQRLECEKQQIQNDLNQWK 1868
Score = 57.0 bits (136), Expect = 2e-07
Identities = 121/610 (19%), Positives = 231/610 (37%), Gaps = 73/610 (11%)
Query: 223 DLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSA---ISNHGSKI 279
DL GE++ + + Q + ++ +E Q K LRN NY++ + + +
Sbjct: 852 DLGKFGEKVTQLTDRWQRIDKQIDF--RLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQ 909
Query: 280 EGLER-ELTDLNQEFETLQEKAQVNSR------KAQTLNNNVNRATQSAKELDVKIKNVI 332
+ LE + D N L E+ ++S K++ + S K+ ++++ +
Sbjct: 910 DSLESMKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYT 969
Query: 333 RNVHILLK-QISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFG---------KHLRE 382
+ LL I T + PSG +E A+ EL R+ K L +
Sbjct: 970 SGLETLLNIPIKRTMIQS---PSGVILQEAADVHARYIELLTRSGDYYRFLSEMLKSLED 1026
Query: 383 AEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQ 442
+ + ++L +R + + EN + +L +Y+A+ S +A+L +Q
Sbjct: 1027 LKLKNTKIEVLEEELRLARDANS-ENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQ 1085
Query: 443 ANGLNQENERALGAIQRQVKEIN--------SLQSDFTKYLTTADSSLLQTNIALQLMEK 494
A + ++ L Q+KE+N ++ + + + D Q N QL +
Sbjct: 1086 AELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKA 1145
Query: 495 SQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNA 554
Q E E L E+ + + +K E+ R + L EE + ELAK RN
Sbjct: 1146 RQCEKENLGWQKLESEKAIKEKEYEIERL--RVLLQEEGTRKREYENELAK-----VRNH 1198
Query: 555 SGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNS 614
+E+ T IK + + L + +E+ K + + N
Sbjct: 1199 YNEEMSNLRNKYETEINITKTTIKEISMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLND 1258
Query: 615 DKL--------LNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQ--------KEVIDTNLT 658
L E + QK E+ +L+ L V Q K+ ++
Sbjct: 1259 SILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEAAK 1318
Query: 659 TLRDGLHGIQRGDIDAMISSAK------SMVRKANDITDEVLDGLNPIQTDVERIKDTYG 712
T++D I+R + + + + + N+ +E++ N +T++ K T
Sbjct: 1319 TIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNNYDEEIISLKNQFETEINITKTTIH 1378
Query: 713 R---TQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQ 769
+ + ED DN LT + L +I+ + L ++N+ R+ E IQ
Sbjct: 1379 QLTMQKEEDTSGYRAQIDN----LTRENRSLSEEIKRLKNTLT---QTTENLRRVEEDIQ 1431
Query: 770 QARDAASKVA 779
Q + S+V+
Sbjct: 1432 QQKATGSEVS 1441
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 82.4 bits (202), Expect = 3e-15
Identities = 55/181 (30%), Positives = 78/181 (43%), Gaps = 34/181 (18%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAG 103
C+P Y +R +G C C+CNGHS C G+C NC+ +T G
Sbjct: 293 CAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEG 352
Query: 104 EHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
++CERCQ Y+ G ++ +C +C C + G + +C CK G +C+
Sbjct: 353 KNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Query: 159 RCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEECDD 212
C PG+ G NPQ C C CN G C +G C+ P P +CD
Sbjct: 412 LCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRCLCL-PNVVGP--KCDQ 464
Query: 213 C 213
C
Sbjct: 465 C 465
Score = 72.4 bits (176), Expect = 4e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 78 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 116
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 117 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 169 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 213
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
Score = 70.5 bits (171), Expect = 1e-11
Identities = 139/702 (19%), Positives = 268/702 (38%), Gaps = 119/702 (16%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQ 110
C PG+ Y + +G C C+CN ++ C + SG C+ C N G C++C
Sbjct: 413 CKPGFTGLTYANPQG-----CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCA 466
Query: 111 EGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC-----ERCAPGYF 165
++ A C C C NS + C N +C C+ G+ G C +C +
Sbjct: 467 PYHWKLASGQGCEPCACDPHNSLSPQC--NQFTGQCPCREGFGGLMCSAAAIRQCPDRTY 524
Query: 166 GNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECD-----------DC 213
G+ C+ C C+ G G C +G C+ + ++C C
Sbjct: 525 GD---VATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Query: 214 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 273
C T DL + +++ L + GL + R + ++ D ++++ R+ +S
Sbjct: 582 HPCFQTYDADLREQALRFGRLRNATASLWSGPGL--EDRGLASRILDAKSKIEQIRAVLS 639
Query: 274 NH----------GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKE 323
+ S I L R L L + L+E+ R ++L+ + N
Sbjct: 640 SPAVTEQEVAQVASAILSLRRTLQGLQLDL-PLEEETLSLPRDLESLDRSFN-------- 690
Query: 324 LDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDF---SREWAEAQRMMRELRNRNFGKHL 380
+ + + ++IS D PSG F S + ++ + +++ + + + L
Sbjct: 691 ---GLLTMYQRKREQFEKISSAD------PSGAFRMLSTAYEQSAQAAQQVSDSS--RLL 739
Query: 381 REAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA 440
+ +RE++ L+ + G G + +L + L DL + +
Sbjct: 740 DQLRDSRREAERLVRQ--------AGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNS 791
Query: 441 KQ---------ANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 491
+Q Q+N A G+ R V + F A+ L N LQ
Sbjct: 792 RQMACTPISCPGELCPQDNGTACGSRCRGV--LPRAGGAFLMAGQVAE-QLRGFNAQLQR 848
Query: 492 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 551
+ + E+ A+ + + Q L +V SA ++ + E+ + +Q++ L +
Sbjct: 849 TRQMIRAAEESASQIQSSAQRLETQV-----SASRSQMEEDVRRTRLLIQQVRDFLTDPD 903
Query: 552 RNASGDELVRCAVDA---ATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAK 608
+A+ + V AV A T +L + + A R + QT K+D+ R A+
Sbjct: 904 TDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT--KQDIAR-AR 960
Query: 609 TLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQ 668
L + ++ EA+ ++ +V + NL+Q V +Q+ +D + G
Sbjct: 961 RLQAEAE----EARSRAHAVEGQVEDVVGNLRQ--GTVALQE---------AQDTMQGTS 1005
Query: 669 RG--DIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIK 708
R I ++ + ++R A + + L T +E ++
Sbjct: 1006 RSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELR 1047
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 82.4 bits (202), Expect = 3e-15
Identities = 55/181 (30%), Positives = 78/181 (43%), Gaps = 34/181 (18%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAG 103
C+P Y +R +G C C+CNGHS C G+C NC+ +T G
Sbjct: 293 CAPFYNNRPWRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEG 352
Query: 104 EHCERCQEGYY-----GNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCE 158
++CERCQ Y+ G ++ +C +C C + G + +C CK G +C+
Sbjct: 353 KNCERCQLHYFRNRRPGASIQETCISCEC-DPDGAVPGAPCDPVTGQCVCKEHVQGERCD 411
Query: 159 RCAPGYFG----NPQKFGGSCQPCSCNSNGQLGS--CHPLTGDCINQEPKDSSPAEECDD 212
C PG+ G NPQ C C CN G C +G C+ P P +CD
Sbjct: 412 LCKPGFTGLTYANPQ----GCHRCDCNILGSRRDMPCDEESGRCLCL-PNVVGP--KCDQ 464
Query: 213 C 213
C
Sbjct: 465 C 465
Score = 72.4 bits (176), Expect = 4e-12
Identities = 54/170 (31%), Positives = 73/170 (42%), Gaps = 40/170 (23%)
Query: 78 CNCNGHSNQCQDGSG-------------ICVNCQHNTAGEHCERCQEGY--------YGN 116
C C+GH+++C G +CV CQHNTAG +CERC Y G
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 117 AVHGSCRACPC-PHTNS-------FATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNP 168
H C+ C C H+ + FA GG V +C+ G CERC YF N
Sbjct: 309 DAH-ECQRCDCNGHSETCHFDPAVFAASQGAYGG-VCDNCRDHTEGKNCERCQLHYFRNR 366
Query: 169 Q---KFGGSCQPCSCNSNGQL--GSCHPLTGDCINQEPKDSSPAEECDDC 213
+ +C C C+ +G + C P+TG C+ K+ E CD C
Sbjct: 367 RPGASIQETCISCECDPDGAVPGAPCDPVTGQCV---CKEHVQGERCDLC 413
Score = 70.5 bits (171), Expect = 1e-11
Identities = 139/702 (19%), Positives = 268/702 (38%), Gaps = 119/702 (16%)
Query: 59 CSPGY----YRDHKGLYTGRCVPCNCNGHSNQ----CQDGSGICVNCQHNTAGEHCERCQ 110
C PG+ Y + +G C C+CN ++ C + SG C+ C N G C++C
Sbjct: 413 CKPGFTGLTYANPQG-----CHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQCA 466
Query: 111 EGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQC-----ERCAPGYF 165
++ A C C C NS + C N +C C+ G+ G C +C +
Sbjct: 467 PYHWKLASGQGCEPCACDPHNSLSPQC--NQFTGQCPCREGFGGLMCSAAAIRQCPDRTY 524
Query: 166 GNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECD-----------DC 213
G+ C+ C C+ G G C +G C+ + ++C C
Sbjct: 525 GD---VATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVAC 581
Query: 214 DSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAIS 273
C T DL + +++ L + GL + R + ++ D ++++ R+ +S
Sbjct: 582 HPCFQTYDADLREQALRFGRLRNATASLWSGPGL--EDRGLASRILDAKSKIEQIRAVLS 639
Query: 274 NH----------GSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKE 323
+ S I L R L L + L+E+ R ++L+ + N
Sbjct: 640 SPAVTEQEVAQVASAILSLRRTLQGLQLDL-PLEEETLSLPRDLESLDRSFN-------- 690
Query: 324 LDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDF---SREWAEAQRMMRELRNRNFGKHL 380
+ + + ++IS D PSG F S + ++ + +++ + + + L
Sbjct: 691 ---GLLTMYQRKREQFEKISSAD------PSGAFRMLSTAYEQSAQAAQQVSDSS--RLL 739
Query: 381 REAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQA 440
+ +RE++ L+ + G G + +L + L DL + +
Sbjct: 740 DQLRDSRREAERLVRQ--------AGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNS 791
Query: 441 KQ---------ANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQL 491
+Q Q+N A G+ R V + F A+ L N LQ
Sbjct: 792 RQMACTPISCPGELCPQDNGTACGSRCRGV--LPRAGGAFLMAGQVAE-QLRGFNAQLQR 848
Query: 492 MEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK 551
+ + E+ A+ + + Q L +V SA ++ + E+ + +Q++ L +
Sbjct: 849 TRQMIRAAEESASQIQSSAQRLETQV-----SASRSQMEEDVRRTRLLIQQVRDFLTDPD 903
Query: 552 RNASGDELVRCAVDA---ATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAK 608
+A+ + V AV A T +L + + A R + QT K+D+ R A+
Sbjct: 904 TDAATIQEVSEAVLALWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQT--KQDIAR-AR 960
Query: 609 TLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQ 668
L + ++ EA+ ++ +V + NL+Q V +Q+ +D + G
Sbjct: 961 RLQAEAE----EARSRAHAVEGQVEDVVGNLRQ--GTVALQE---------AQDTMQGTS 1005
Query: 669 RG--DIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIK 708
R I ++ + ++R A + + L T +E ++
Sbjct: 1006 RSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGDFWTRMEELR 1047
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,088,390
Number of Sequences: 37866
Number of extensions: 3195547
Number of successful extensions: 15563
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 839
Number of HSP's that attempted gapping in prelim test: 10436
Number of HSP's gapped (non-prelim): 3733
length of query: 1724
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1608
effective length of database: 13,855,062
effective search space: 22278939696
effective search space used: 22278939696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.