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Search of human proteins with 37221184
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
(736 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens] 1496 0.0
gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens] 1496 0.0
gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens] 1496 0.0
gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens] 1496 0.0
gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens] 1368 0.0
gi|13994263 FERM domain containing 8 [Homo sapiens] 100 4e-21
gi|18079216 CASK interacting protein 1 [Homo sapiens] 70 7e-12
gi|41327754 ankyrin repeat domain 3 [Homo sapiens] 69 2e-11
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 69 2e-11
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 68 3e-11
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 67 8e-11
gi|116534990 ankyrin-like protein 1 [Homo sapiens] 64 4e-10
gi|50511945 cajalin 2 isoform a [Homo sapiens] 63 1e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 61 4e-09
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 60 6e-09
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 59 1e-08
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 59 1e-08
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 59 1e-08
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 59 1e-08
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 59 1e-08
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 59 1e-08
gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 59 2e-08
gi|140161500 ankyrin repeat and sterile alpha motif domain conta... 58 3e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 57 5e-08
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens] 57 6e-08
gi|24233530 ankyrin repeat domain 44 [Homo sapiens] 56 1e-07
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 56 1e-07
gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Ho... 56 1e-07
gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens] 56 1e-07
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ... 56 1e-07
>gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1496 bits (3872), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 721 LLMKLNGQLMPTERNS 736
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1496 bits (3872), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 721 LLMKLNGQLMPTERNS 736
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1496 bits (3872), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 721 LLMKLNGQLMPTERNS 736
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]
Length = 736
Score = 1496 bits (3872), Expect = 0.0
Identities = 736/736 (100%), Positives = 736/736 (100%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
Query: 721 LLMKLNGQLMPTERNS 736
LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736
>gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]
Length = 688
Score = 1368 bits (3541), Expect = 0.0
Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)
Query: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1 MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
Query: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61 NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282
Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312
Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372
Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432
Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492
Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552
Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612
Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672
Query: 721 LLMKLNGQLMPTERNS 736
LLMKLNGQLMPTERNS
Sbjct: 673 LLMKLNGQLMPTERNS 688
>gi|13994263 FERM domain containing 8 [Homo sapiens]
Length = 464
Score = 100 bits (250), Expect = 4e-21
Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)
Query: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
+ E ++L F +W+ S L +QLKP H+P + R WPE+L T+ D +
Sbjct: 61 VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120
Query: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
P L RR+V P E QI D + +L++EA+ N+L Y L +L+ ++
Sbjct: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180
Query: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
G Y+ + L E+ L S +P K ++A +L+ Y+
Sbjct: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239
Query: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
+S+ G + R +L C E+P YG AFF G++ A H+ PV V ++++
Sbjct: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299
Query: 666 GLHLLNMETKALLISLKYGCFMW 688
G+H+++ K +L+ L++ W
Sbjct: 300 GVHVIDSREKHVLLGLRFQELSW 322
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 70.1 bits (170), Expect = 7e-12
Identities = 37/107 (34%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G++EL+S LL + +V+ D+ P+HYA W G+ E +++L+ G N+
Sbjct: 53 LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNIP 111
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CE 397
+ + PLH AA GH ++ ++LL H +++ + D G++PL++ CE
Sbjct: 112 SDEGHIPLHLAAQHGHYDVSEMLLQH-QSNPCMVDNSGKTPLDLACE 157
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 8/116 (6%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A +G E + +L +VN + P+H A +G + + +LL+ + NP +
Sbjct: 85 PLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQH-QSNPCM 143
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH-------PETDRHITDQQGRSPLNICEEN 399
++ +PL A G +VQ+LL+ TD G SPL++ +N
Sbjct: 144 VDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKN 199
Score = 48.5 bits (114), Expect = 2e-05
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 7/92 (7%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G ++ LL + + +D+ P+ AC +G+V ++LL C L
Sbjct: 118 PLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALL 177
Query: 351 -------LNGQLSSPLHFAAGGGHAEIVQILL 375
+ +SPLH AA GH +I+++LL
Sbjct: 178 EPRPGDATDPNGTSPLHLAAKNGHIDIIRLLL 209
Score = 33.9 bits (76), Expect = 0.56
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)
Query: 318 DSDHWAPIHYACWYGKVEATRILLEKG-KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
D + +P+H A G ++ R+LL+ G N +G + LH AA G E+V++LL+
Sbjct: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG---TALHEAALCGKTEVVRLLLD 242
Query: 377 HPETDRHITDQQGRSPLNICEE-NKQNNWEEAAKLLKEA 414
+ H+ + ++ L+I + E +LL+EA
Sbjct: 243 -SGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREA 280
>gi|41327754 ankyrin repeat domain 3 [Homo sapiens]
Length = 784
Score = 68.6 bits (166), Expect = 2e-11
Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 4/122 (3%)
Query: 277 SVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEA 336
SV E QW LH +A GD LL + SVN++D + P+H AC +G+
Sbjct: 496 SVNAKDEDQWT---ALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENI 552
Query: 337 TRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 396
RILL +G + +L PLH+AA GH IV++L P + GR+PL++
Sbjct: 553 VRILLRRG-VDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLA 611
Query: 397 EE 398
+
Sbjct: 612 AQ 613
Score = 55.8 bits (133), Expect = 1e-07
Identities = 39/153 (25%), Positives = 71/153 (46%), Gaps = 11/153 (7%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
P+H + G ++ LL V+ D W P+HYA W G + ++L ++ + N
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNA 599
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH AA GH + +IL++ +D ++ ++PL++ E + A+L
Sbjct: 600 QTLDGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTS---TARL 655
Query: 411 L------KEAINKP-YEKVRIYRMDGSYRSVEL 436
L KEA+ Y + + +G +V+L
Sbjct: 656 LLHRGAGKEAMTSDGYTALHLAARNGHLATVKL 688
Score = 55.5 bits (132), Expect = 2e-07
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 8/139 (5%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + ++ LL+ + SVN D D W +H+A G +TR+LLEK + N
Sbjct: 474 PLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEK-NASVNE 532
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
++ + +P+H A G IV+ILL D + + PL+ W+ +
Sbjct: 533 VDFEGRTPMHVACQHGQENIVRILLRR-GVDVSLQGKDAWLPLHYAA------WQGHLPI 585
Query: 411 LKEAINKPYEKVRIYRMDG 429
+K +P V +DG
Sbjct: 586 VKLLAKQPGVSVNAQTLDG 604
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G + LL + SD + +H A G + ++L+E+ L
Sbjct: 640 PLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKA--DVL 697
Query: 351 LNGQLS-SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENK 400
G L+ + LH AA GH+E+V+ L++ D + D+QG S L++ + +
Sbjct: 698 ARGPLNQTALHLAAAHGHSEVVEELVSADVID--LFDEQGLSALHLAAQGR 746
Score = 34.7 bits (78), Expect = 0.33
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 2/86 (2%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G + L+ E+ V + +H A +G E L+ + L
Sbjct: 674 LHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVID--LF 731
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+ Q S LH AA G HA+ V+ LL H
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRH 757
Score = 33.5 bits (75), Expect = 0.73
Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Query: 299 GDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 358
GD+ L ++L + LDS + +H A G+ E + LL NPNL N + S+P
Sbjct: 417 GDTSKLMKILQPQDVDLALDSGA-SLLHLAVEAGQEECAKWLL-LNNANPNLSNRRGSTP 474
Query: 359 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
LH A +V++LL + + D+ + L+ QN E + +LL E
Sbjct: 475 LHMAVERRVRGVVELLLAR-KISVNAKDEDQWTALHFA---AQNGDESSTRLLLE 525
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/108 (37%), Positives = 66/108 (61%), Gaps = 5/108 (4%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPNL 350
LH +A G EL++ LL + +V+ DS+ P+HYA W G++E R+LL N
Sbjct: 53 LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS 112
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CE 397
L+GQ+ PLH AA GH E+ ++LL H +++ + ++ ++PL++ CE
Sbjct: 113 LDGQI--PLHLAAQYGHYEVSEMLLQH-QSNPCLVNKAKKTPLDLACE 157
Score = 52.4 bits (124), Expect = 2e-06
Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A +G E + LL +VN D P+H A YG E + +LL+ + NP L
Sbjct: 85 PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH-QSNPCL 143
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLN 376
+N +PL A G ++ Q+LLN
Sbjct: 144 VNKAKKTPLDLACEFGRLKVAQLLLN 169
Score = 44.7 bits (104), Expect = 3e-04
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 17/97 (17%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-------- 342
PLH +A G E+ LL + + ++ P+ AC +G+++ ++LL
Sbjct: 118 PLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALL 177
Query: 343 ----KGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL 375
K C+PN ++PLH AA GH E+++ LL
Sbjct: 178 EGEAKDPCDPN-----YTTPLHLAAKNGHREVIRQLL 209
Score = 38.1 bits (87), Expect = 0.029
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G E++ +LL +N+ A +H A YGK E R+LLE G + N+
Sbjct: 192 PLHLAAKNGHREVIRQLLRAGIEINRQTKTGTA-LHEAALYGKTEVVRLLLE-GGVDVNI 249
Query: 351 LNGQLSSPL----HFAAGGGHAEIVQIL 374
N + L F EI Q+L
Sbjct: 250 RNTYNQTALDIVNQFTTSQASREIKQLL 277
Score = 31.2 bits (69), Expect = 3.6
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 1/62 (1%)
Query: 333 KVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSP 392
K T++L + N N + S LH AA GG E++ +LL T I D G P
Sbjct: 27 KATKTKLLGSTKRLNVNYQDADGFSALHHAALGGSLELIALLLEAQAT-VDIKDSNGMRP 85
Query: 393 LN 394
L+
Sbjct: 86 LH 87
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 67.8 bits (164), Expect = 3e-11
Identities = 70/266 (26%), Positives = 116/266 (43%), Gaps = 19/266 (7%)
Query: 160 LDKWLDERHAQSHFIPALFRPSPLERIKTNV-INPAYATES-GQTENSLHMGYSALEIKS 217
+ K + E+ + +P PS E ++ +P + +E+ G+ S + YS E
Sbjct: 48 VSKEMKEKSSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPE 107
Query: 218 KMLALEKADTCIYNP---LFGSDLQYTNRVD---KVVINPYFGLGAPDYSKIQIPKQEKW 271
K ++A P LFG L ++ ++ P++ P Q+K
Sbjct: 108 KKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQTTPAQKKT 167
Query: 272 QRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYAC 329
S SS +DK +R + PLH +A GD + + L+S +VN D W P+H AC
Sbjct: 168 PSS-SSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEAC 226
Query: 330 WYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 389
G + +IL+ G + N +PLH +A GH +IV++LL H ++ G
Sbjct: 227 NVGYYDVAKILIAAG-ADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQ-ANKHG 284
Query: 390 RSPLNICEENKQNNWEEAAKLLKEAI 415
P+++ E EE LLK +
Sbjct: 285 ERPVDVAET------EELELLLKREV 304
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 66.6 bits (161), Expect = 8e-11
Identities = 50/160 (31%), Positives = 77/160 (48%), Gaps = 11/160 (6%)
Query: 258 PDYSKIQIPKQEKWQRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVN 315
P++ P Q+K S SS +DK +R + PLH +A GD + + L+S +VN
Sbjct: 131 PNHPSQTTPAQKKTPSS-SSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVN 189
Query: 316 QLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL 375
D W P+H AC G + +IL+ G + N +PLH +A GH +IV++LL
Sbjct: 190 VKDFAGWTPLHEACNVGYYDVAKILIAAG-ADVNTQGLDDDTPLHDSASSGHRDIVKLLL 248
Query: 376 NHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
H ++ G P+++ E EE LLK +
Sbjct: 249 RHGGNPFQ-ANKHGERPVDVAET------EELELLLKREV 281
>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
Length = 1119
Score = 64.3 bits (155), Expect = 4e-10
Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Query: 287 VDDFPLHRSACEGDSELLSRLL--SERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG 344
+D F LH +A EG EL+ ++ S ++++D P+H A ++E+ + LL +G
Sbjct: 62 MDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRG 121
Query: 345 KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNN 403
NPNL N + +PLH A G + E++++LL H D ++ + G + + I C N
Sbjct: 122 -ANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNN--- 177
Query: 404 WEEAAKLLKEAINKP 418
EA ++L + KP
Sbjct: 178 -SEALQILLKKGAKP 191
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + +G ++ LL S++ D +P+H+A YG++ + LL+ L
Sbjct: 416 PLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLL 475
Query: 351 LNGQL--SSPLHFAAGGGHAEIVQILL 375
G L +PLH AA GH ++VQ+LL
Sbjct: 476 NEGDLHGMTPLHLAAKNGHDKVVQLLL 502
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 15/147 (10%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +++ +LL ++ ++ D + W +H+A G + +++L+ +
Sbjct: 485 PLHLAAKNGHDKVV-QLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDR 543
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ--------- 401
L+ ++ LHFAA GHA+ V +LL+H D + QQ S L++ NK+
Sbjct: 544 LDEDGNTALHFAAREGHAKAVALLLSH-NADIVLNKQQA-SFLHLALHNKRKEVVLTIIR 601
Query: 402 -NNWEEAAKLLKEAINKPYEKVRIYRM 427
W+E K+ N P K I M
Sbjct: 602 SKRWDECLKIFSH--NSPGNKCPITEM 626
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + GD E++ L ++ ++ IH+A G E ++++ + ++
Sbjct: 242 PLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDI 301
Query: 351 LN---GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
+N G + LH A+ H E+ L++ D + D +GRSPL
Sbjct: 302 VNTTDGCHETMLHRASLFDHHELADYLIS-VGADINKIDSEGRSPL 346
Score = 37.0 bits (84), Expect = 0.066
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)
Query: 318 DSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
D+D P+HYAC G + LL + + + SPLHFAA G Q LL
Sbjct: 410 DNDGCTPLHYACRQGGPGSVNNLL-GFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQD 468
Query: 378 PETDRHIT--DQQGRSPLNICEEN 399
R + D G +PL++ +N
Sbjct: 469 ISDTRLLNEGDLHGMTPLHLAAKN 492
Score = 35.4 bits (80), Expect = 0.19
Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 300 DSELLSRLLSERFSVNQLDSDHWA--PIHYACWYGKVEATRILLEKGK-------CNPNL 350
+SE L LL + S+ W PIH A + G E I+L G+ + N
Sbjct: 177 NSEALQILLKK--GAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINF 234
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
+N ++PLH A G E++++ L++
Sbjct: 235 MNNGKATPLHLAVQNGDLEMIKMCLDN 261
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 62.8 bits (151), Expect = 1e-09
Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 3/106 (2%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP--N 349
LH +A G +++ +LL S N D+ + PIH A W G VE +IL+ G + N
Sbjct: 63 LHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVN 122
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N + + LH AA GH+E+V +LL TD I + + +PL++
Sbjct: 123 EQNNENETALHCAAQYGHSEVVAVLLEE-LTDPTIRNSKLETPLDL 167
Score = 50.4 bits (119), Expect = 6e-06
Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 5/93 (5%)
Query: 290 FPLHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKC 346
FP+H +A +GD E++ L+ S VN+ ++++ +H A YG E +LLE+
Sbjct: 94 FPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEE-LT 152
Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLN-HP 378
+P + N +L +PL AA G +V+++++ HP
Sbjct: 153 DPTIRNSKLETPLDLAALYGRLRVVKMIISAHP 185
Score = 48.5 bits (114), Expect = 2e-05
Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 36/155 (23%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G SE+++ LL E +S P+ A YG++ ++++ +PNL+
Sbjct: 132 LHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIIS---AHPNLM 188
Query: 352 --NGQLSSPLHFAAGGGHAEIVQILLN-------------------------------HP 378
N + +PLH AA GH +VQ+LL
Sbjct: 189 SCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLET 248
Query: 379 ETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
D +I D GR+ L+I +E+ + A LL+E
Sbjct: 249 GIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQE 283
Score = 41.6 bits (96), Expect = 0.003
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Query: 304 LSRLLS--ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHF 361
LS LLS +VN DS + +H+A G + LL+ + + N+ + + P+H
Sbjct: 40 LSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQY-EASTNVADNKGYFPIHL 98
Query: 362 AAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
AA G EIV+IL++H + + +Q + + + + E A LL+E
Sbjct: 99 AAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEE 150
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 4/129 (3%)
Query: 269 EKWQRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
+K + +S T+DK +R + LHR+A GD+ + L+SE VN D W +H
Sbjct: 147 QKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALH 206
Query: 327 YACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITD 386
AC G + + LL G N +PLH AA GH ++V++LL + + ++
Sbjct: 207 EACNRGYYDVAKQLLAAG-AEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQ-SN 264
Query: 387 QQGRSPLNI 395
++G +PL +
Sbjct: 265 RKGETPLKV 273
>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
sapiens]
Length = 226
Score = 60.5 bits (145), Expect = 6e-09
Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 7/122 (5%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G E++ LL + VN ++ + P+HYA + E +LLE G NP+
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANPDA 134
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNNWEEAAK 409
+ ++ +H AA G+ +++ ILL + + +I D +G +PL++ C+E + E AK
Sbjct: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEER----VEEAK 189
Query: 410 LL 411
LL
Sbjct: 190 LL 191
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 8/129 (6%)
Query: 302 ELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHF 361
EL +L+++ + D D +H+AC G E LL+ G N + SPLH
Sbjct: 21 ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHI 79
Query: 362 AAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKP--- 418
AA G EIV+ LL + +Q G +PL+ +N E A LL+ N
Sbjct: 80 AASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAA--SKNRHEIAVMLLEGGANPDAKD 136
Query: 419 -YEKVRIYR 426
YE ++R
Sbjct: 137 HYEATAMHR 145
Score = 42.4 bits (98), Expect = 0.002
Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 1/74 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
+HR+A +G+ +++ LL + S N D++ P+H AC +VE ++L+ +G + +
Sbjct: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG-ASIYIE 201
Query: 352 NGQLSSPLHFAAGG 365
N + +PL A GG
Sbjct: 202 NKEEKTPLQVAKGG 215
Score = 30.4 bits (67), Expect = 6.2
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 5/66 (7%)
Query: 332 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL--LNHPETDRHITDQQG 389
GK+E + + K + + LH+A GH EIV+ L L P D+ D G
Sbjct: 17 GKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAG 73
Query: 390 RSPLNI 395
SPL+I
Sbjct: 74 WSPLHI 79
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +E+ LL + VN D P+H A G ++LLE NPNL
Sbjct: 473 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 531
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH AA GH E V LL E + ++G +PL++
Sbjct: 532 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 575
Score = 57.0 bits (136), Expect = 6e-08
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG E + LL + S + + P+H A YGKV +LLE+ +PN
Sbjct: 539 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 597
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A + +IV++LL + H G +PL+I KQN E A L
Sbjct: 598 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 654
Query: 411 LK 412
L+
Sbjct: 655 LQ 656
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + ++ LL S++ + P+H A + G + + LL++G +PN+
Sbjct: 407 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 465
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
N ++ +PLH AA GH E+ + LL +
Sbjct: 466 SNVKVETPLHMAARAGHTEVAKYLLQN 492
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A + + LL ++ + DH P+H A G ++LL+KG K N
Sbjct: 341 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 400
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A H ++++LL + +T + G +PL++
Sbjct: 401 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 443
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W PLH +A + E+ LL S N P+H A G E +LL K +
Sbjct: 633 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 691
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N NL N +PLH A GH + +L+ H T + G +PL++
Sbjct: 692 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 740
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + + LL+ SVN + P+H A G V R+LL++G
Sbjct: 242 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 301
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
+L +PLH AA GH I +ILL+H + T + G SP+++ +
Sbjct: 302 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 347
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S + + + P+H A +VE R LL+ G + N
Sbjct: 605 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 663
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH AA GHAE+V +LL+ + + ++ ++ G +PL++
Sbjct: 664 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 707
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A EG + L+ V+ + P+H A YG ++ + LL+ + + N
Sbjct: 704 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 762
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
SPLH AA GH +IV +LL + + ++ G +PL I +
Sbjct: 763 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 808
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG +E+++ LLS++ + N + P+H G V +L++ G +
Sbjct: 671 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 729
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A+ G+ ++V+ LL H + D + + G SPL+ + +Q + + L
Sbjct: 730 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 786
Query: 411 LK 412
LK
Sbjct: 787 LK 788
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH +A G + ++ LL + N + P+H A G VE LLEK + +
Sbjct: 503 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 561
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
+ + +PLH AA G + ++LL E D H + G +PL++
Sbjct: 562 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 608
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
PLH ++ G+ ++ LL + D P+H A G V + ILL+ G
Sbjct: 275 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 334
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
NG SP+H AA G H + V++LL +
Sbjct: 335 TKNGL--SPIHMAAQGDHLDCVRLLLQY 360
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ L++ +VN + P++ A +E + LLE G N N+
Sbjct: 115 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 173
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+PL A GH +V L+N+
Sbjct: 174 TEDGFTPLAVALQQGHENVVAHLINY 199
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH ++ G+ +L+ LL + VN ++P+H A G + +LL+ G +PN
Sbjct: 737 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 795
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
++ ++PL A G+ + +L
Sbjct: 796 VSSDGTTPLAIAKRLGYISVTDVL 819
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A D+ + LL + + L + P+H A Y + ++LL +G + N
Sbjct: 210 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 268
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
+PLH A+ G+ +V++LL+
Sbjct: 269 PQNGITPLHIASRRGNVIMVRLLLD 293
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +E+ LL + VN D P+H A G ++LLE NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH AA GH E V LL E + ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542
Score = 57.0 bits (136), Expect = 6e-08
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG E + LL + S + + P+H A YGKV +LLE+ +PN
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A + +IV++LL + H G +PL+I KQN E A L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621
Query: 411 LK 412
L+
Sbjct: 622 LQ 623
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + ++ LL S++ + P+H A + G + + LL++G +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
N ++ +PLH AA GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A + + LL ++ + DH P+H A G ++LL+KG K N
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A H ++++LL + +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W PLH +A + E+ LL S N P+H A G E +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N NL N +PLH A GH + +L+ H T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + + LL+ SVN + P+H A G V R+LL++G
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
+L +PLH AA GH I +ILL+H + T + G SP+++ +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S + + + P+H A +VE R LL+ G + N
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH AA GHAE+V +LL+ + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A EG + L+ V+ + P+H A YG ++ + LL+ + + N
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
SPLH AA GH +IV +LL + + ++ G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG +E+++ LLS++ + N + P+H G V +L++ G +
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A+ G+ ++V+ LL H + D + + G SPL+ + +Q + + L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753
Query: 411 LK 412
LK
Sbjct: 754 LK 755
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH +A G + ++ LL + N + P+H A G VE LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
+ + +PLH AA G + ++LL E D H + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
PLH ++ G+ ++ LL + D P+H A G V + ILL+ G
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
NG SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ L++ +VN + P++ A +E + LLE G N N+
Sbjct: 82 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+PL A GH +V L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH ++ G+ +L+ LL + VN ++P+H A G + +LL+ G +PN
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
++ ++PL A G+ + +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A D+ + LL + + L + P+H A Y + ++LL +G + N
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
+PLH A+ G+ +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +E+ LL + VN D P+H A G ++LLE NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH AA GH E V LL E + ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542
Score = 57.0 bits (136), Expect = 6e-08
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG E + LL + S + + P+H A YGKV +LLE+ +PN
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A + +IV++LL + H G +PL+I KQN E A L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621
Query: 411 LK 412
L+
Sbjct: 622 LQ 623
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + ++ LL S++ + P+H A + G + + LL++G +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
N ++ +PLH AA GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A + + LL ++ + DH P+H A G ++LL+KG K N
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A H ++++LL + +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W PLH +A + E+ LL S N P+H A G E +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N NL N +PLH A GH + +L+ H T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + + LL+ SVN + P+H A G V R+LL++G
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
+L +PLH AA GH I +ILL+H + T + G SP+++ +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S + + + P+H A +VE R LL+ G + N
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH AA GHAE+V +LL+ + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A EG + L+ V+ + P+H A YG ++ + LL+ + + N
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
SPLH AA GH +IV +LL + + ++ G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG +E+++ LLS++ + N + P+H G V +L++ G +
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A+ G+ ++V+ LL H + D + + G SPL+ + +Q + + L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753
Query: 411 LK 412
LK
Sbjct: 754 LK 755
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH +A G + ++ LL + N + P+H A G VE LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
+ + +PLH AA G + ++LL E D H + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
PLH ++ G+ ++ LL + D P+H A G V + ILL+ G
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
NG SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ L++ +VN + P++ A +E + LLE G N N+
Sbjct: 82 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+PL A GH +V L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH ++ G+ +L+ LL + VN ++P+H A G + +LL+ G +PN
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
++ ++PL A G+ + +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A D+ + LL + + L + P+H A Y + ++LL +G + N
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
+PLH A+ G+ +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +E+ LL + VN D P+H A G ++LLE NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH AA GH E V LL E + ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542
Score = 57.0 bits (136), Expect = 6e-08
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG E + LL + S + + P+H A YGKV +LLE+ +PN
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A + +IV++LL + H G +PL+I KQN E A L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621
Query: 411 LK 412
L+
Sbjct: 622 LQ 623
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + ++ LL S++ + P+H A + G + + LL++G +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
N ++ +PLH AA GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A + + LL ++ + DH P+H A G ++LL+KG K N
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A H ++++LL + +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W PLH +A + E+ LL S N P+H A G E +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N NL N +PLH A GH + +L+ H T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + + LL+ SVN + P+H A G V R+LL++G
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
+L +PLH AA GH I +ILL+H + T + G SP+++ +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S + + + P+H A +VE R LL+ G + N
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH AA GHAE+V +LL+ + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A EG + L+ V+ + P+H A YG ++ + LL+ + + N
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
SPLH AA GH +IV +LL + + ++ G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG +E+++ LLS++ + N + P+H G V +L++ G +
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A+ G+ ++V+ LL H + D + + G SPL+ + +Q + + L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753
Query: 411 LK 412
LK
Sbjct: 754 LK 755
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH +A G + ++ LL + N + P+H A G VE LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
+ + +PLH AA G + ++LL E D H + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
PLH ++ G+ ++ LL + D P+H A G V + ILL+ G
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
NG SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ L++ +VN + P++ A +E + LLE G N N+
Sbjct: 82 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+PL A GH +V L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH ++ G+ +L+ LL + VN ++P+H A G + +LL+ G +PN
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
++ ++PL A G+ + +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A D+ + LL + + L + P+H A Y + ++LL +G + N
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
+PLH A+ G+ +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G +E+ LL + VN D P+H A G ++LLE NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH AA GH E V LL E + ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542
Score = 57.0 bits (136), Expect = 6e-08
Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG E + LL + S + + P+H A YGKV +LLE+ +PN
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A + +IV++LL + H G +PL+I KQN E A L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621
Query: 411 LK 412
L+
Sbjct: 622 LQ 623
Score = 51.6 bits (122), Expect = 3e-06
Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + ++ LL S++ + P+H A + G + + LL++G +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
N ++ +PLH AA GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459
Score = 50.1 bits (118), Expect = 8e-06
Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A + + LL ++ + DH P+H A G ++LL+KG K N
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A H ++++LL + +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W PLH +A + E+ LL S N P+H A G E +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N NL N +PLH A GH + +L+ H T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + + LL+ SVN + P+H A G V R+LL++G
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
+L +PLH AA GH I +ILL+H + T + G SP+++ +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S + + + P+H A +VE R LL+ G + N
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH AA GHAE+V +LL+ + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674
Score = 47.8 bits (112), Expect = 4e-05
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A EG + L+ V+ + P+H A YG ++ + LL+ + + N
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
SPLH AA GH +IV +LL + + ++ G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG +E+++ LLS++ + N + P+H G V +L++ G +
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH A+ G+ ++V+ LL H + D + + G SPL+ + +Q + + L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753
Query: 411 LK 412
LK
Sbjct: 754 LK 755
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH +A G + ++ LL + N + P+H A G VE LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
+ + +PLH AA G + ++LL E D H + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575
Score = 43.9 bits (102), Expect = 5e-04
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
PLH ++ G+ ++ LL + D P+H A G V + ILL+ G
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
NG SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ L++ +VN + P++ A +E + LLE G N N+
Sbjct: 82 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
+PL A GH +V L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166
Score = 40.0 bits (92), Expect = 0.008
Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH ++ G+ +L+ LL + VN ++P+H A G + +LL+ G +PN
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
++ ++PL A G+ + +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786
Score = 36.2 bits (82), Expect = 0.11
Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A D+ + LL + + L + P+H A Y + ++LL +G + N
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
+PLH A+ G+ +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 59.3 bits (142), Expect = 1e-08
Identities = 34/108 (31%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH S +G E++ L++ VN D++ + + A W G V+ ++L+E G +
Sbjct: 983 LHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTC 1042
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEEN 399
N Q ++ L AA GH ++VQ+LL H H DQ GR+ + + +N
Sbjct: 1043 N-QGATALCIAAQEGHIDVVQVLLEHGADPNH-ADQFGRTAMRVAAKN 1088
Score = 47.8 bits (112), Expect = 4e-05
Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PL +A +G +++++ L+ ++N D D W + A W G E LL G +
Sbjct: 581 PLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG-VKVDC 639
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
+ + L AA GGH +IV LL H + + D +GR+ L
Sbjct: 640 ADADSRTALRAAAWGGHEDIVLNLLQH-GAEVNKADNEGRTAL 681
Score = 47.0 bits (110), Expect = 6e-05
Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A EG + L+ + N++D+D P A G + +ILLE K N +
Sbjct: 850 PLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-NKSNIDQ 908
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ L AA GH +IV++L +H D + D GR L I
Sbjct: 909 RGYDGRNALRVAALEGHRDIVELLFSH-GADVNCKDADGRPTLYI 952
Score = 43.9 bits (102), Expect = 5e-04
Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 4/122 (3%)
Query: 296 ACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQL 355
A +G + ++S L+ V+ D D P+ A + G V+ +LLE G + + +
Sbjct: 723 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLE-GGADVDHTDNNG 781
Query: 356 SSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
+PL AA GHA +V LL I D +GR+ L+I + Q N E LL +
Sbjct: 782 RTPLLAAASMGHASVVNTLLFWGAAVDSI-DSEGRTVLSIA--SAQGNVEVVRTLLDRGL 838
Query: 416 NK 417
++
Sbjct: 839 DE 840
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 2/104 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
L +A G +E++S LL V+ D+D + A W G + LL+ G N
Sbjct: 615 LRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHG-AEVNKA 673
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ + + L AA GH EIV+ LL+H H D GR+ L++
Sbjct: 674 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNH-EDVDGRTALSV 716
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 10/126 (7%)
Query: 271 WQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACW 330
W ++ S+ D E + V L ++ +G+ E++ LL N D W P+H A +
Sbjct: 803 WGAAVDSI--DSEGRTV----LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF 856
Query: 331 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL-NHPETDRHITDQQG 389
G L+E+G N ++ P A+ GH + VQILL N D+ D G
Sbjct: 857 EGHRLICEALIEQG-ARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYD--G 913
Query: 390 RSPLNI 395
R+ L +
Sbjct: 914 RNALRV 919
Score = 37.4 bits (85), Expect = 0.050
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)
Query: 294 RSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNG 353
R A E + + + LL SVNQ DS+ + A + G ++ +L+ +G + + +
Sbjct: 519 RQALEREDSIRT-LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRG-ADLEIEDA 576
Query: 354 QLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
+PL AA GH ++V L+ H TDQ G + L
Sbjct: 577 HGHTPLTLAARQGHTKVVNCLIGCGANINH-TDQDGWTAL 615
Score = 37.4 bits (85), Expect = 0.050
Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
L +A EG +++ L S VN D+D ++ ++ LE G N
Sbjct: 917 LRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG-ANVEAS 975
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
+ + + LH + GH E+VQ+L+ + D + D + RS L
Sbjct: 976 DAEGRTALHVSCWQGHMEMVQVLIAY-HADVNAADNEKRSAL 1016
>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
Length = 1076
Score = 58.5 bits (140), Expect = 2e-08
Identities = 38/129 (29%), Positives = 66/129 (51%), Gaps = 2/129 (1%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PL ++ D E + LLS++ ++N LD + P+H A + G V ++LL G N
Sbjct: 8 DQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG-AN 66
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEA 407
N + +PLH AA + +++ +LL H D + D+ ++PL++ N+ EA
Sbjct: 67 VNAKDTLWLTPLHRAAASRNEKVLGLLLAH-SADVNARDKLWQTPLHVAAANRATKCAEA 125
Query: 408 AKLLKEAIN 416
L ++N
Sbjct: 126 LAPLLSSLN 134
Score = 44.7 bits (104), Expect = 3e-04
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Query: 317 LDSDHWAPIHYACWYGKVEATRILLEKGKCNP--NLLNGQLSSPLHFAAGGGHAEIVQIL 374
LD + +H AC G + ++L + + N N L PLH AA G A +VQ L
Sbjct: 921 LDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQAL 980
Query: 375 LNHPETDRHITDQQGRSPLNICEENK 400
L+H T + D++G +P C NK
Sbjct: 981 LSHGATVLAV-DEEGHTPALACAPNK 1005
Score = 43.9 bits (102), Expect = 5e-04
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 4/113 (3%)
Query: 282 KERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILL 341
K+ W+ PLHR+A + ++L LL+ VN D P+H A + L
Sbjct: 70 KDTLWLT--PLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALA 127
Query: 342 EKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
+ N+ + S LH A GH E V +LLN ++ D++ R PL+
Sbjct: 128 PL-LSSLNVADRSGRSALHHAVHSGHLETVNLLLN-KGASLNVCDKKERQPLH 178
Score = 43.5 bits (101), Expect = 7e-04
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A ++ L S+N D + +H+A G +E +LL KG + N+
Sbjct: 110 PLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKG-ASLNV 168
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILL 375
+ + PLH+AA GH E++++L+
Sbjct: 169 CDKKERQPLHWAAFLGHLEVLKLLV 193
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G E++ LL +++ ++ +H AC+ G+ +A I L N N
Sbjct: 210 LHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQ-DAVAIELVNAGANVNQP 268
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N + +PLH AA + + LL + D + ++G+SPL++
Sbjct: 269 NDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHM 312
Score = 42.4 bits (98), Expect = 0.002
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH + G E ++ LL++ S+N D P+H+A + G +E ++L+ +G +
Sbjct: 144 LHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG-ADLGCK 202
Query: 352 NGQLSSPLHFAAGGGHAEIVQILL 375
+ + LH AA G E+V+ LL
Sbjct: 203 DRKGYGLLHTAAASGQIEVVKYLL 226
Score = 42.4 bits (98), Expect = 0.002
Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 21/150 (14%)
Query: 270 KWQRSMSSVTEDKERQWVDDF---PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
++ RS + E D F PLH +A G L+S L++ + P+H
Sbjct: 318 RFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLH 377
Query: 327 YACWYGKVEATRILLEKGK--------CNPNLLNG--QLSSP-------LHFAAGGGHAE 369
A +G + R LL G+ N ++L+ +++P LH AA GG+ E
Sbjct: 378 LAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVE 437
Query: 370 IVQILLNHPETDRHITDQQGRSPLNICEEN 399
+ +LL+ D D+ GR+PL+ N
Sbjct: 438 CLNLLLS-SGADLRRRDKFGRTPLHYAAAN 466
Score = 42.0 bits (97), Expect = 0.002
Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 8/137 (5%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KC 346
+D PL S + L LL + D + +HYA YG + +LLE C
Sbjct: 517 EDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNC 576
Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEE 406
++ + SPLH AA GH E ++ L + + D +GR+ L + E E
Sbjct: 577 LEDVESTIPVSPLHLAAYNGHCEALKTLA-ETLVNLDVRDHKGRTALFLATERGSTECVE 635
Query: 407 ------AAKLLKEAINK 417
A+ L+KE K
Sbjct: 636 VLTAHGASALIKERKRK 652
Score = 41.2 bits (95), Expect = 0.003
Identities = 35/124 (28%), Positives = 64/124 (51%), Gaps = 10/124 (8%)
Query: 276 SSVTEDKERQWVDDFPLHRSACEGDSELLSRLLS--ERFSVNQ-LDSDHWAPIHYACWYG 332
S++ ++++R+W PLH +A G ++ L L+ ER + +D+ P+ A G
Sbjct: 643 SALIKERKRKWT---PLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNG 699
Query: 333 KVEATRILLEKGK-CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 391
V+ +LLEKG + L G+ + LH A G + + LL+H + D +GR+
Sbjct: 700 HVDCVHLLLEKGSTADAADLRGR--TALHRGAVTGCEDCLAALLDH-DAFVLCRDFKGRT 756
Query: 392 PLNI 395
P+++
Sbjct: 757 PIHL 760
Score = 39.3 bits (90), Expect = 0.013
Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LHR A G + L+ LL V D PIH A G R LL+ L
Sbjct: 725 LHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLD 784
Query: 352 NG---QLSSPLHFAAGGGHAEIVQILLNH 377
G SP+H+A+ GH + +++LL H
Sbjct: 785 AGVDYSGYSPMHWASYTGHEDCLELLLEH 813
Score = 38.1 bits (87), Expect = 0.029
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 7/109 (6%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDS----DHWAPIHYACWYGKVEATRILLEKGKC 346
P+H ++ G + +L LL S + LD+ ++P+H+A + G + +LLE
Sbjct: 757 PIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPF 816
Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETD-RHITDQQGRSPLN 394
+ L G +PLH A ++LL + D +GR+PL+
Sbjct: 817 --SYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLH 863
Score = 37.7 bits (86), Expect = 0.039
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 6/113 (5%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G E L L +++ D + A G E +L G
Sbjct: 588 PLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIK 647
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPE----TDRHITDQQGRSPLNICEEN 399
+ +PLH AA GH + + +L++ E TD + D G++PL + N
Sbjct: 648 ERKRKWTPLHAAAASGHTDSLHLLIDSGERADITD--VMDAYGQTPLMLAIMN 698
Score = 36.2 bits (82), Expect = 0.11
Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G+ E L+ LLS + + D P+HYA G + L+ G N
Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAG-AGVNEA 485
Query: 352 NGQLSSPLHFAA 363
+ + SPLH+AA
Sbjct: 486 DCKGCSPLHYAA 497
Score = 34.7 bits (78), Expect = 0.33
Identities = 38/169 (22%), Positives = 67/169 (39%), Gaps = 31/169 (18%)
Query: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYAC---WY 331
+SS + + R PLH +A G + L++ VN+ D +P+HYA Y
Sbjct: 443 LSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTY 502
Query: 332 GKVE-------------------------ATRILLEKGKCNPNLLNGQLSSPLHFAAGGG 366
+ E LL+ G +P+L + Q + +H+AA G
Sbjct: 503 RRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNG-ADPSLRDRQGYTAVHYAAAYG 561
Query: 367 HAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
+ + +++LL + + D + P++ N EA K L E +
Sbjct: 562 NRQNLELLLE--MSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETL 608
Score = 34.3 bits (77), Expect = 0.43
Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 3/105 (2%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH + G + L++ +VNQ + + P+H A LL + N
Sbjct: 243 LHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQ 302
Query: 352 NGQLSSPLHFAAGGGHAEIVQILL-NHPETDRHITDQQGRSPLNI 395
+ + SPLH AA G QIL+ N E D D+ G +PL++
Sbjct: 303 SKEGKSPLHMAAIHGRFTRSQILIQNGSEID--CADKFGNTPLHV 345
>gi|140161500 ankyrin repeat and sterile alpha motif domain
containing 1 [Homo sapiens]
Length = 1134
Score = 58.2 bits (139), Expect = 3e-08
Identities = 33/93 (35%), Positives = 57/93 (61%), Gaps = 5/93 (5%)
Query: 290 FPLHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKC 346
+PLH +A +GD++++ L+ + S VN+ ++D+ +H A YG E ++LLE+
Sbjct: 115 YPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE-LT 173
Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLN-HP 378
+P + N + +PL AA G E+V++LLN HP
Sbjct: 174 DPTMRNNKFETPLDLAALYGRLEVVKMLLNAHP 206
Score = 57.4 bits (137), Expect = 5e-08
Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP-- 348
PLH +A G +++ LL N DS P+H A W G + R+L+ +G +
Sbjct: 83 PLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRV 142
Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N N + LH AA GH E+V++LL TD + + + +PL++
Sbjct: 143 NEQNNDNETALHCAAQYGHTEVVKVLLEE-LTDPTMRNNKFETPLDL 188
Score = 52.0 bits (123), Expect = 2e-06
Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 5/102 (4%)
Query: 277 SVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEA 336
S T E+ ++ LH +A G +E++ LL E ++ P+ A YG++E
Sbjct: 138 SHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEV 197
Query: 337 TRILLEKGKCNPNLL--NGQLSSPLHFAAGGGHAEIVQILLN 376
++LL +PNLL N + +PLH AA GH +VQ+LL+
Sbjct: 198 VKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLD 236
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%)
Query: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKV 334
+ +T+ R + PL +A G E++ LL+ ++ ++ P+H A G
Sbjct: 169 LEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHK 228
Query: 335 EATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
++LL+ G + ++ S LH AA G ++VQILL TD +I D G + L+
Sbjct: 229 AVVQVLLDAGM--DSNYQTEMGSALHEAALFGKTDVVQILL-AAGTDVNIKDNHGLTALD 285
Query: 395 ICEENKQNNWEEAAKLLKE 413
E ++ A L+++
Sbjct: 286 TVRELPSQKSQQIAALIED 304
Score = 43.9 bits (102), Expect = 5e-04
Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 6/121 (4%)
Query: 301 SELLSRLLS--ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 358
S LS LLS +VN +DS + P+H+A G + +LL + N+ + + P
Sbjct: 58 SHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL-RNDALTNVADSKGCYP 116
Query: 359 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNNWEEAAKLLKEAINK 417
LH AA G A+IV++L++ + + +Q + + C Q E K+L E +
Sbjct: 117 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCA--AQYGHTEVVKVLLEELTD 174
Query: 418 P 418
P
Sbjct: 175 P 175
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 10/106 (9%)
Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEE 406
N N ++ +PLH AA GH ++V++LL + + ++ D +G PL++ W+
Sbjct: 72 NVNCVDSTGYTPLHHAALNGHKDVVEVLLRN-DALTNVADSKGCYPLHLAA------WKG 124
Query: 407 AAKLLKEAINKPYEKVRIYRMDGSYRSV---ELKHGNNTTVQQIME 449
A++++ I++ R+ + + ++G+ V+ ++E
Sbjct: 125 DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLE 170
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 57.4 bits (137), Expect = 5e-08
Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 10/160 (6%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH SA EG ++ + LL S++ + P+H A YGK+E +LL+K +P+
Sbjct: 535 PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK-SASPDA 593
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
+PLH AA + ++ +LL+ + H + G +PL+I K+N + A L
Sbjct: 594 AGKSGLTPLHVAAHYDNQKVALLLLDQGASP-HAAAKNGYTPLHIAA--KKNQMDIATTL 650
Query: 411 LK------EAINKPYEKVRIYRMDGSYRSVELKHGNNTTV 444
L+ + V + +G V L G N V
Sbjct: 651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690
Score = 54.7 bits (130), Expect = 3e-07
Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 4/123 (3%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G +E++ L+ + V D P+H + GK + + LL++G +PN
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAA 528
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
+PLH +A GH ++ LL+H IT ++G +PL++ K E A LL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDH-GASLSITTKKGFTPLHVAA--KYGKLEVANLLL 585
Query: 412 KEA 414
+++
Sbjct: 586 QKS 588
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 3/96 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPN 349
PLH +A E + L+++ V+ + P+H C YG ++ LL+ K N
Sbjct: 700 PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 759
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT 385
NG +PLH AA GH I+ +LL + + +T
Sbjct: 760 TKNGY--TPLHQAAQQGHTHIINVLLQNNASPNELT 793
Score = 47.8 bits (112), Expect = 4e-05
Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 10/159 (6%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH ++ EG E++S LL +V+ +H A G+ E ++L+ G N N
Sbjct: 78 LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG-ANVNAQ 136
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
+ +PL+ AA H E+V+ LL++ + + + G +PL + Q ++ LL
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDN-GASQSLATEDGFTPLAVA---LQQGHDQVVSLL 192
Query: 412 -----KEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQ 445
K + P + + D ++ L++ NN V+
Sbjct: 193 LENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVE 231
Score = 47.8 bits (112), Expect = 4e-05
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPN- 349
PLH + + LL V+ + +D+ +H A G + ++LL+K K NPN
Sbjct: 337 PLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK-KANPNA 395
Query: 350 -LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
LNG +PLH A +++++LL H + + +T + G +P+++
Sbjct: 396 KALNG--FTPLHIACKKNRIKVMELLLKHGASIQAVT-ESGLTPIHV 439
Score = 44.7 bits (104), Expect = 3e-04
Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 4/114 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
PLH +A G+ + + LL+ +V+ + P+H A G ++LL++G K +
Sbjct: 238 PLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAK 297
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNN 403
+G +PLH A GH ++V++LL+ T + G SPL++ + N
Sbjct: 298 TRDG--LTPLHCGARSGHEQVVEMLLDRAAPILSKT-KNGLSPLHMATQGDHLN 348
Score = 43.9 bits (102), Expect = 5e-04
Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 11/113 (9%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + + +++ LL S+ + PIH A + G V L+ G +PN
Sbjct: 403 PLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG-ASPNT 461
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILL----------NHPETDRHITDQQGRSPL 393
N + + LH AA G AE+V+ L+ +T HI+ + G++ +
Sbjct: 462 TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADI 514
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 2/110 (1%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A G ++ LL ++ + N + + P+H AC +++ +LL+ G +
Sbjct: 371 LHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVT 430
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
L +P+H AA GH IV L++H + + T+ +G + L++ + Q
Sbjct: 431 ESGL-TPIHVAAFMGHVNIVSQLMHHGASP-NTTNVRGETALHMAARSGQ 478
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
D PLH ++ G++ ++ LL ++ D P+H G + +LL++
Sbjct: 268 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPI 327
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
+ LS PLH A G H VQ+LL H
Sbjct: 328 LSKTKNGLS-PLHMATQGDHLNCVQLLLQH 356
Score = 39.7 bits (91), Expect = 0.010
Identities = 26/117 (22%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Query: 260 YSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDS 319
++ + + Q+ + +S + E+ + V LH +A + D++ + LL + +
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESK 233
Query: 320 DHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
+ P+H A YG + +LL + + +PLH A+ G+A +V++LL+
Sbjct: 234 SGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-TPLHVASKRGNANMVKLLLD 289
Score = 39.7 bits (91), Expect = 0.010
Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 3/111 (2%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH A G +++ LL + + +P+H A + ++LL+ ++
Sbjct: 304 PLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDV 363
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENK 400
N L++ LH AA GH ++ ++LL+ + + + G +PL+I C++N+
Sbjct: 364 TNDYLTA-LHVAAHCGHYKVAKVLLD-KKANPNAKALNGFTPLHIACKKNR 412
Score = 38.9 bits (89), Expect = 0.017
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
P+H +A G ++S+L+ S N + +H A G+ E R L++ G +
Sbjct: 436 PIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK 495
Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ Q +PLH +A G A+IVQ LL + T G +PL++
Sbjct: 496 AKDDQ--TPLHISARLGKADIVQQLLQQGASPNAAT-TSGYTPLHL 538
>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
Length = 1378
Score = 57.0 bits (136), Expect = 6e-08
Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 13/134 (9%)
Query: 267 KQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
K KW R R + + LHR+ EG + L+ + +N D W P+H
Sbjct: 518 KGSKWNR----------RNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLH 567
Query: 327 YACWYGKVEATRILLEKGKC--NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHI 384
AC YG +E R LL+ G +P + +PLH A GH E+ ++LL + +
Sbjct: 568 EACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVT-L 626
Query: 385 TDQQGRSPLNICEE 398
++G SPL ++
Sbjct: 627 RTRKGLSPLETLQQ 640
>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
Length = 919
Score = 56.2 bits (134), Expect = 1e-07
Identities = 47/182 (25%), Positives = 82/182 (45%), Gaps = 11/182 (6%)
Query: 282 KERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILL 341
+++ W PLH +A + ++ SVN D +H+A G VE +LL
Sbjct: 78 RDKNW--QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 135
Query: 342 EKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
KG N N + + LH+AA GH ++V +L+NH + D++G +PL+ N Q
Sbjct: 136 AKG-ANINAFDKKDRRALHWAAYMGHLDVVALLINH-GAEVTCKDKKGYTPLHAAASNGQ 193
Query: 402 NNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLSQETQQY 460
N ++K +N E I + + +G + V ++++ G ++Q
Sbjct: 194 IN------VVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNG 247
Query: 461 FT 462
FT
Sbjct: 248 FT 249
Score = 52.8 bits (125), Expect = 1e-06
Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 1/105 (0%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G ++ LL+ +++++ +H AC+ G+ L++ G N N
Sbjct: 184 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG-ANVNQ 242
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N +PLHFAA H + LL + D +I + G+SPL++
Sbjct: 243 PNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287
Score = 50.4 bits (119), Expect = 6e-06
Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 2/110 (1%)
Query: 307 LLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGG 366
L+ + VN LDS+ P+H A + G E +L+ G N + +PLH A
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSG-ARVNAKDNMWLTPLHRAVASR 60
Query: 367 HAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAIN 416
E VQ+L+ H D + D+ ++PL++ NK E L ++N
Sbjct: 61 SEEAVQVLIKH-SADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVN 109
Score = 48.9 bits (115), Expect = 2e-05
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQL---DSDHWAPIHYACWYGKVEATRILLEKGKCN 347
PLH +A G + LS LL S D+ + P+H+AC+ G +LLE+ KC
Sbjct: 714 PLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQ-KCF 772
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETD-RHITDQQGRSPL 393
+ G +PLH A H +LL ++ D +GR+PL
Sbjct: 773 RKFI-GNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPL 818
Score = 47.0 bits (110), Expect = 6e-05
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 7/130 (5%)
Query: 291 PLHRSACEGDS---ELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
PLH S G + LL + +V+ D+ P+ A YG ++A +LLEK + N
Sbjct: 612 PLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEK-EAN 670
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEA 407
+ ++ + LH GH E VQ+LL E D +GR+PL+ W
Sbjct: 671 VDTVDILGCTALHRGIMTGHEECVQMLLEQ-EVSILCKDSRGRTPLHYAAARGHATW--L 727
Query: 408 AKLLKEAINK 417
++LL+ A+++
Sbjct: 728 SELLQMALSE 737
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 318 DSDHWAPIHYACWYGKVEATRILLEKGKCN-PNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
D + + IHYA YG + +LLE+ +G SPLH AA GH + +++LL
Sbjct: 504 DKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLL- 562
Query: 377 HPETDRHITDQQGRSPLNI 395
D I D++GR+ L++
Sbjct: 563 QSLVDLDIRDEKGRTALDL 581
Score = 42.4 bits (98), Expect = 0.002
Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 16/112 (14%)
Query: 290 FPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG----- 344
FPLH +A S+ +LLS F ++ D +H A G VE ++L G
Sbjct: 349 FPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHK 408
Query: 345 --KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
KC +PLH+AA H ++ L+ + + TD GR+ L+
Sbjct: 409 KDKCG--------RTPLHYAAANCHFHCIETLVT-TGANVNETDDWGRTALH 451
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 2/104 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A GD+E++ L+ VN D+ P+H A EA ++L+ K + N
Sbjct: 19 PLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLI-KHSADVNA 77
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
+ +PLH AA + ++++ + +++D+ GR+ L+
Sbjct: 78 RDKNWQTPLHVAAANKAVKCAEVII-PLLSSVNVSDRGGRTALH 120
Score = 40.0 bits (92), Expect = 0.008
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 5/114 (4%)
Query: 274 SMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGK 333
S+ S +DK R PL +A E L LL VN +D+ + A G+
Sbjct: 805 SIVSCRDDKGRT-----PLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQ 859
Query: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 387
A IL+ + + + + L++PLH A GH + ++L+ + + I ++
Sbjct: 860 AGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEK 913
Score = 38.5 bits (88), Expect = 0.023
Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 19/140 (13%)
Query: 270 KWQRSMSSVTEDKERQWVD---DFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
++ RS + + E VD + PLH +A G L++ L + + P+H
Sbjct: 293 RFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLH 352
Query: 327 YACWYGKVEATRILLEKGKCNPNLLNGQLSSP-------LHFAAGGGHAEIVQILLNHPE 379
A + R LL G ++ +P LH AA GG+ E ++ LL
Sbjct: 353 LAALNAHSDCCRKLLSSG--------FEIDTPDKFGRTCLHAAAAGGNVECIK-LLQSSG 403
Query: 380 TDRHITDQQGRSPLNICEEN 399
D H D+ GR+PL+ N
Sbjct: 404 ADFHKKDKCGRTPLHYAAAN 423
Score = 38.1 bits (87), Expect = 0.029
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKV----EATRILLEKGKCN 347
LHR G E + LL + S+ DS P+HYA G E ++ L + C
Sbjct: 682 LHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDC- 740
Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILL 375
+ Q +PLH+A G+ +++LL
Sbjct: 741 -CFKDNQGYTPLHWACYNGNENCIEVLL 767
Score = 33.5 bits (75), Expect = 0.73
Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 3/107 (2%)
Query: 291 PLHRSACEGDSELLSRLLSERFS--VNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
PLH + S LL S V+ D P+ A + VE ++LL +
Sbjct: 782 PLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLL-RHSAPV 840
Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
N ++ + L AA G A V IL+N + D + D+ +PL++
Sbjct: 841 NAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHL 887
Score = 33.1 bits (74), Expect = 0.95
Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 5/88 (5%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWA---PIHYACWYGKVEATRILLEKGKCNP 348
+H +A G + L LL ER + +SD A P+H A + G +A +LL+ +
Sbjct: 511 IHYAAAYGHRQCLELLL-ERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQS-LVDL 568
Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLN 376
++ + + + L AA GH E V+ L+N
Sbjct: 569 DIRDEKGRTALDLAAFKGHTECVEALIN 596
Score = 32.7 bits (73), Expect = 1.2
Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 28/137 (20%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYG----------------KV 334
PLH +A + L++ +VN+ D +HYA ++
Sbjct: 416 PLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEEL 475
Query: 335 EATRILLEK-----------GKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH 383
E R L EK NP++ + + + +H+AA GH + +++LL +
Sbjct: 476 ERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFE 535
Query: 384 ITDQQG-RSPLNICEEN 399
+D +SPL++ N
Sbjct: 536 ESDSGATKSPLHLAAYN 552
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 56.2 bits (134), Expect = 1e-07
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 5/120 (4%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
LH +A + + LL +VN L + + +HYA G + +R+L+ G C N++
Sbjct: 229 LHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGC-ANVV 287
Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
+ Q +SPLH A +V++L+N ++D + D + ++PL++ E+ W++ A +L
Sbjct: 288 DHQGASPLHLAVRHNFPALVRLLIN-SDSDVNAVDNRQQTPLHLAAEHA---WQDIADML 343
Score = 37.4 bits (85), Expect = 0.050
Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
Query: 293 HRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLN 352
HR+A G + L L+ N D + +H A G + + L++ G + N
Sbjct: 164 HRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG-LDLEEQN 222
Query: 353 GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 387
+ + LH AAGG H + VQ+LL T +T +
Sbjct: 223 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQK 257
Score = 33.5 bits (75), Expect = 0.73
Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 13/133 (9%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + L+ L++ VN +D+ P+H A + + +LL G + NL
Sbjct: 294 PLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG-VDLNL 352
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDR----HITDQQGRSPLNICEENKQNN--- 403
+ Q + L A H +V +++ R H +D G+S L+ ++++Q
Sbjct: 353 RDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKS-LSFKQDHRQETQQL 411
Query: 404 ----WEEAAKLLK 412
W A++ L+
Sbjct: 412 RSVLWRLASRYLQ 424
Score = 31.6 bits (70), Expect = 2.8
Identities = 43/175 (24%), Positives = 74/175 (42%), Gaps = 26/175 (14%)
Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPNL 350
LH +A + + + L+ R + + +H+A G +A R+LLE + +
Sbjct: 19 LHEAARQNNVGRMQELIGRRVNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEED 78
Query: 351 LNGQLS--------SPLHFAAGGGHAEIVQILLN-----HPE-----TDRHITDQQGRSP 392
G L+ + L +A GH I+QIL+N H E T H Q+G P
Sbjct: 79 AVGALTEARLCFGMNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVP 138
Query: 393 L--NICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMD-----GSYRSVELKHGN 440
+ I E+ + + KL + A ++ E ++ +D G +V+ K GN
Sbjct: 139 VLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGN 193
>gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Homo
sapiens]
Length = 329
Score = 56.2 bits (134), Expect = 1e-07
Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 1/92 (1%)
Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
W D PLH +A +G L LLS+ ++VN + DH P+H AC V R LLE G
Sbjct: 68 WADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAG- 126
Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
N N + +PL A G ++LL +
Sbjct: 127 ANVNAITIDGVTPLFNACSQGSPSCAELLLEY 158
Score = 33.5 bits (75), Expect = 0.73
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
P H +A +G E L L+S V+Q P++ AC + LL G ++
Sbjct: 171 PTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAG---ADV 227
Query: 351 LNGQL-SSPLHFAAGGGHAEIVQILL 375
G+ +PLH AA EIV +LL
Sbjct: 228 QKGKYWDTPLHAAAQQSSTEIVNLLL 253
Score = 30.4 bits (67), Expect = 6.2
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 271 WQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACW 330
W+ + K + W D PLH +A + +E+++ LL +N +++ PI A
Sbjct: 218 WKLLYAGADVQKGKYW--DTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS 275
Query: 331 YGKVEATRILLE 342
VE RILL+
Sbjct: 276 SSMVE--RILLQ 285
>gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]
Length = 614
Score = 56.2 bits (134), Expect = 1e-07
Identities = 32/109 (29%), Positives = 62/109 (56%), Gaps = 5/109 (4%)
Query: 291 PLHRSACEGDSELLSRLLSER--FSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
PLH + E D LL+ LL + +N D++ P+H+A ++ + + T++LL+KG +P
Sbjct: 130 PLHAATAEPDMRLLTVLLQQSNISEINHQDNEGMTPLHWAAFHNQPQHTQMLLKKG-ADP 188
Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT--DQQGRSPLNI 395
L++ + LH+A G+ + I+L+H + I D+ G++ ++I
Sbjct: 189 TLVDKDFKTALHWAVQSGNRILCSIILSHHQGPSIINYDDESGKTCVHI 237
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)
Query: 292 LHRSACEGDSELLSRLLS-ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
+H +A G S+++ L ++ LD D P+H+A GK E + LLE G + NL
Sbjct: 235 VHIAAAAGFSDIIHELARVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLELGM-DSNL 293
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETD 381
+ S+PL +A GH V++L T+
Sbjct: 294 RDINESTPLAYALYCGHTACVKLLSQESRTE 324
Score = 36.2 bits (82), Expect = 0.11
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 292 LHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
LH + G+ L S +LS +N D +H A G + L +CN
Sbjct: 199 LHWAVQSGNRILCSIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHELARVPECNL 258
Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
L+ +PLH+AA G AE VQ LL D ++ D +PL
Sbjct: 259 QALDVDDRTPLHWAAAAGKAECVQSLL-ELGMDSNLRDINESTPL 302
>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
sapiens]
Length = 765
Score = 55.8 bits (133), Expect = 1e-07
Identities = 30/105 (28%), Positives = 58/105 (55%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PL +A + +L + LL+ N++D D WAP+H+A G R+LL+ G C +
Sbjct: 398 PLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGAC-VDA 456
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+ +PLH AA + ++L++ + D ++ + +G++PL++
Sbjct: 457 QEREGWTPLHLAAQNNFENVARLLVSR-QADPNLHEAEGKTPLHV 500
Score = 47.0 bits (110), Expect = 6e-05
Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A G + LL S+ W P+H A + G +E +L E N
Sbjct: 563 PLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE-SHANMGA 621
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
L +PLH AA G +V LL D + +Q G +PL++
Sbjct: 622 LGAVNWTPLHLAARHGEEAVVSALL-QCGADPNAAEQSGWTPLHL 665
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 2/105 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A +G E++ L ++ L + +W P+H A +G+ LL+ G +PN
Sbjct: 596 PLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG-ADPNA 654
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
+PLH A V LL H + H ++ G +P ++
Sbjct: 655 AEQSGWTPLHLAVQRSTFLSVINLLEH-HANVHARNKVGWTPAHL 698
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH + G + LL + LD + P+H A GK ++LL G + L
Sbjct: 530 PLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYG-ASLEL 588
Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
Q +PLH AA GH EI+ +L
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLL 612
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)
Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
PLH +A + L+S + N +++ P+H A ++G V ++L +G +
Sbjct: 464 PLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQG-AELDA 522
Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
L +PLH A G +Q LL + DQ G PL+
Sbjct: 523 QQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDAL-DQSGYGPLH 565
Score = 31.2 bits (69), Expect = 3.6
Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)
Query: 324 PIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH 383
P+H+ G VE R+LL + + + +PL AA ++ +LL H D +
Sbjct: 365 PLHFLVAQGSVEQVRLLLAH-EVDVDCQTASGYTPLLIAAQDQQPDLCALLLAH-GADAN 422
Query: 384 ITDQQGRSPLNICEEN 399
D+ G +PL+ +N
Sbjct: 423 RVDEDGWAPLHFAAQN 438
Score = 30.4 bits (67), Expect = 6.2
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)
Query: 357 SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
+PLHF G E V++LL H E D G +PL I +++Q
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAH-EVDVDCQTASGYTPLLIAAQDQQ 407
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,424,782
Number of Sequences: 37866
Number of extensions: 1214611
Number of successful extensions: 4788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 3063
Number of HSP's gapped (non-prelim): 1164
length of query: 736
length of database: 18,247,518
effective HSP length: 110
effective length of query: 626
effective length of database: 14,082,258
effective search space: 8815493508
effective search space used: 8815493508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.