Guide to the Human Genome
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Search of human proteins with 37221184

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
         (736 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]      1496   0.0  
gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]      1496   0.0  
gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]      1496   0.0  
gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]      1496   0.0  
gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]      1368   0.0  
gi|13994263 FERM domain containing 8 [Homo sapiens]                   100   4e-21
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  70   7e-12
gi|41327754 ankyrin repeat domain 3 [Homo sapiens]                     69   2e-11
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       69   2e-11
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]         68   3e-11
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]         67   8e-11
gi|116534990 ankyrin-like protein 1 [Homo sapiens]                     64   4e-10
gi|50511945 cajalin 2 isoform a [Homo sapiens]                         63   1e-09
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    61   4e-09
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ...    60   6e-09
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        59   1e-08
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         59   1e-08
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         59   1e-08
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         59   1e-08
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         59   1e-08
gi|62988328 ankyrin repeat domain 50 [Homo sapiens]                    59   1e-08
gi|157743284 ankyrin repeat domain 52 [Homo sapiens]                   59   2e-08
gi|140161500 ankyrin repeat and sterile alpha motif domain conta...    58   3e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]                         57   5e-08
gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]        57   6e-08
gi|24233530 ankyrin repeat domain 44 [Homo sapiens]                    56   1e-07
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ...    56   1e-07
gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Ho...    56   1e-07
gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]          56   1e-07
gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo ...    56   1e-07

>gi|37221184 krev interaction trapped 1 isoform 1 [Homo sapiens]
          Length = 736

 Score = 1496 bits (3872), Expect = 0.0
 Identities = 736/736 (100%), Positives = 736/736 (100%)

Query: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
           MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60

Query: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
           NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120

Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
           TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180

Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
           SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240

Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
           TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300

Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
           SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360

Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
           FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420

Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
           KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480

Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
           LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540

Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
           KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600

Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
           ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660

Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
           GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720

Query: 721 LLMKLNGQLMPTERNS 736
           LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736


>gi|37221182 krev interaction trapped 1 isoform 1 [Homo sapiens]
          Length = 736

 Score = 1496 bits (3872), Expect = 0.0
 Identities = 736/736 (100%), Positives = 736/736 (100%)

Query: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
           MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60

Query: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
           NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120

Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
           TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180

Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
           SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240

Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
           TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300

Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
           SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360

Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
           FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420

Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
           KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480

Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
           LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540

Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
           KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600

Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
           ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660

Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
           GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720

Query: 721 LLMKLNGQLMPTERNS 736
           LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736


>gi|37221187 krev interaction trapped 1 isoform 1 [Homo sapiens]
          Length = 736

 Score = 1496 bits (3872), Expect = 0.0
 Identities = 736/736 (100%), Positives = 736/736 (100%)

Query: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
           MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60

Query: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
           NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120

Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
           TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180

Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
           SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240

Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
           TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300

Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
           SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360

Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
           FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420

Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
           KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480

Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
           LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540

Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
           KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600

Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
           ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660

Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
           GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720

Query: 721 LLMKLNGQLMPTERNS 736
           LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736


>gi|31581522 krev interaction trapped 1 isoform 1 [Homo sapiens]
          Length = 736

 Score = 1496 bits (3872), Expect = 0.0
 Identities = 736/736 (100%), Positives = 736/736 (100%)

Query: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
           MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60

Query: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
           NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120

Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
           TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180

Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
           SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240

Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
           TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300

Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
           SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360

Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
           FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420

Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
           KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480

Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
           LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540

Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
           KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600

Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
           ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660

Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
           GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720

Query: 721 LLMKLNGQLMPTERNS 736
           LLMKLNGQLMPTERNS
Sbjct: 721 LLMKLNGQLMPTERNS 736


>gi|61742817 krev interaction trapped 1 isoform 2 [Homo sapiens]
          Length = 688

 Score = 1368 bits (3541), Expect = 0.0
 Identities = 688/736 (93%), Positives = 688/736 (93%), Gaps = 48/736 (6%)

Query: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60
           MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG
Sbjct: 1   MGNPENIEDAYVAVIRPKNTASLNSREYRAKSYEILLHEVPIEGQKKKRKKVLLETKLQG 60

Query: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120
           NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN
Sbjct: 61  NSEITQGILDYVVETTKPISPANQGIRGKRVVLMKKFPLDGEKMGREASLFIVPSVVKDN 120

Query: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180
           TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP
Sbjct: 121 TKYTYTPGCPIFYCLQDIMRVCSESSTHFATLTARMLIALDKWLDERHAQSHFIPALFRP 180

Query: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240
           SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY
Sbjct: 181 SPLERIKTNVINPAYATESGQTENSLHMGYSALEIKSKMLALEKADTCIYNPLFGSDLQY 240

Query: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGD 300
           TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK                  
Sbjct: 241 TNRVDKVVINPYFGLGAPDYSKIQIPKQEKWQRSMSSVTEDK------------------ 282

Query: 301 SELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLH 360
                                         YGKVEATRILLEKGKCNPNLLNGQLSSPLH
Sbjct: 283 ------------------------------YGKVEATRILLEKGKCNPNLLNGQLSSPLH 312

Query: 361 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 420
           FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE
Sbjct: 313 FAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKPYE 372

Query: 421 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 480
           KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP
Sbjct: 373 KVRIYRMDGSYRSVELKHGNNTTVQQIMEGMRLSQETQQYFTIWICSENLSLQLKPYHKP 432

Query: 481 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 540
           LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL
Sbjct: 433 LQHVRDWPEILAELTNLDPQRETPQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLL 492

Query: 541 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 600
           KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR
Sbjct: 493 KGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEENLKSIVPVTKLKSKAPHWTNR 552

Query: 601 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 660
           ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV
Sbjct: 553 ILHEYKNLSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYV 612

Query: 661 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 720
           GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK
Sbjct: 613 GVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVK 672

Query: 721 LLMKLNGQLMPTERNS 736
           LLMKLNGQLMPTERNS
Sbjct: 673 LLMKLNGQLMPTERNS 688


>gi|13994263 FERM domain containing 8 [Homo sapiens]
          Length = 464

 Score =  100 bits (250), Expect = 4e-21
 Identities = 72/263 (27%), Positives = 123/263 (46%), Gaps = 22/263 (8%)

Query: 447 IMEGMRLSQETQQYFTIWICSENLSLQLKPYHKPLQHVRDWPEILAELTNL---DPQRET 503
           + E ++L       F +W+ S  L +QLKP H+P +  R WPE+L   T+    D   + 
Sbjct: 61  VREVLQLPDIALDVFALWLVSPLLEVQLKPKHQPYKLGRQWPELLLRFTSAPDDDVAMDE 120

Query: 504 PQLFLRRDVRLPLEVEKQIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVY 563
           P L  RR+V  P   E QI D   + +L++EA+ N+L   Y         L +L+ ++  
Sbjct: 121 PFLQFRRNVFFPKRRELQIHDEEVLRLLYEEAKGNVLAARYPCDVEDCEALGALVCRVQL 180

Query: 564 GNYESKKHKQGFLNEENLKSIVPVTKLK-------------SKAPHWTNRILHEYK---N 607
           G Y+  +     L E+ L S +P    K             ++A      +L+ Y+    
Sbjct: 181 GPYQPGRPAACDLREK-LDSFLPAHLCKRGQSLFAALRGRGARAGPGEQGLLNAYRQVQE 239

Query: 608 LSTSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHK--VIPVYVGVNIK 665
           +S+  G    +    R +L  C E+P YG AFF G++   A    H+    PV V ++++
Sbjct: 240 VSSDGGCEAALGTHYRAYLLKCHELPFYGCAFFHGEVDKPAQGFLHRGGRKPVSVAISLE 299

Query: 666 GLHLLNMETKALLISLKYGCFMW 688
           G+H+++   K +L+ L++    W
Sbjct: 300 GVHVIDSREKHVLLGLRFQELSW 322


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 37/107 (34%), Positives = 66/107 (61%), Gaps = 3/107 (2%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G++EL+S LL  + +V+  D+    P+HYA W G+ E  +++L+ G    N+ 
Sbjct: 53  LHHAALNGNTELISLLLEAQAAVDIKDNKGMRPLHYAAWQGRKEPMKLVLKAGSA-VNIP 111

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CE 397
           + +   PLH AA  GH ++ ++LL H +++  + D  G++PL++ CE
Sbjct: 112 SDEGHIPLHLAAQHGHYDVSEMLLQH-QSNPCMVDNSGKTPLDLACE 157



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 8/116 (6%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A +G  E +  +L    +VN    +   P+H A  +G  + + +LL+  + NP +
Sbjct: 85  PLHYAAWQGRKEPMKLVLKAGSAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQH-QSNPCM 143

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH-------PETDRHITDQQGRSPLNICEEN 399
           ++    +PL  A   G   +VQ+LL+               TD  G SPL++  +N
Sbjct: 144 VDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALLEPRPGDATDPNGTSPLHLAAKN 199



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 7/92 (7%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G  ++   LL  + +   +D+    P+  AC +G+V   ++LL    C   L
Sbjct: 118 PLHLAAQHGHYDVSEMLLQHQSNPCMVDNSGKTPLDLACEFGRVGVVQLLLSSNMCAALL 177

Query: 351 -------LNGQLSSPLHFAAGGGHAEIVQILL 375
                   +   +SPLH AA  GH +I+++LL
Sbjct: 178 EPRPGDATDPNGTSPLHLAAKNGHIDIIRLLL 209



 Score = 33.9 bits (76), Expect = 0.56
 Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 6/99 (6%)

Query: 318 DSDHWAPIHYACWYGKVEATRILLEKG-KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
           D +  +P+H A   G ++  R+LL+ G   N    +G   + LH AA  G  E+V++LL+
Sbjct: 186 DPNGTSPLHLAAKNGHIDIIRLLLQAGIDINRQTKSG---TALHEAALCGKTEVVRLLLD 242

Query: 377 HPETDRHITDQQGRSPLNICEE-NKQNNWEEAAKLLKEA 414
               + H+ +   ++ L+I  +        E  +LL+EA
Sbjct: 243 -SGINAHVRNTYSQTALDIVHQFTTSQASREIKQLLREA 280


>gi|41327754 ankyrin repeat domain 3 [Homo sapiens]
          Length = 784

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 42/122 (34%), Positives = 61/122 (50%), Gaps = 4/122 (3%)

Query: 277 SVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEA 336
           SV    E QW     LH +A  GD      LL +  SVN++D +   P+H AC +G+   
Sbjct: 496 SVNAKDEDQWT---ALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENI 552

Query: 337 TRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNIC 396
            RILL +G  + +L       PLH+AA  GH  IV++L   P    +     GR+PL++ 
Sbjct: 553 VRILLRRG-VDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGRTPLHLA 611

Query: 397 EE 398
            +
Sbjct: 612 AQ 613



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 39/153 (25%), Positives = 71/153 (46%), Gaps = 11/153 (7%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           P+H +   G   ++  LL     V+    D W P+HYA W G +   ++L ++   + N 
Sbjct: 540 PMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGVSVNA 599

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH AA  GH  + +IL++   +D ++     ++PL++  E    +    A+L
Sbjct: 600 QTLDGRTPLHLAAQRGHYRVARILIDLC-SDVNVCSLLAQTPLHVAAETGHTS---TARL 655

Query: 411 L------KEAINKP-YEKVRIYRMDGSYRSVEL 436
           L      KEA+    Y  + +   +G   +V+L
Sbjct: 656 LLHRGAGKEAMTSDGYTALHLAARNGHLATVKL 688



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 8/139 (5%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +       ++  LL+ + SVN  D D W  +H+A   G   +TR+LLEK   + N 
Sbjct: 474 PLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEK-NASVNE 532

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
           ++ +  +P+H A   G   IV+ILL     D  +  +    PL+         W+    +
Sbjct: 533 VDFEGRTPMHVACQHGQENIVRILLRR-GVDVSLQGKDAWLPLHYAA------WQGHLPI 585

Query: 411 LKEAINKPYEKVRIYRMDG 429
           +K    +P   V    +DG
Sbjct: 586 VKLLAKQPGVSVNAQTLDG 604



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 5/111 (4%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +     LL        + SD +  +H A   G +   ++L+E+      L
Sbjct: 640 PLHVAAETGHTSTARLLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKA--DVL 697

Query: 351 LNGQLS-SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENK 400
             G L+ + LH AA  GH+E+V+ L++    D  + D+QG S L++  + +
Sbjct: 698 ARGPLNQTALHLAAAHGHSEVVEELVSADVID--LFDEQGLSALHLAAQGR 746



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 2/86 (2%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G    +  L+ E+  V      +   +H A  +G  E    L+     +  L 
Sbjct: 674 LHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELVSADVID--LF 731

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
           + Q  S LH AA G HA+ V+ LL H
Sbjct: 732 DEQGLSALHLAAQGRHAQTVETLLRH 757



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 34/115 (29%), Positives = 54/115 (46%), Gaps = 6/115 (5%)

Query: 299 GDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 358
           GD+  L ++L  +     LDS   + +H A   G+ E  + LL     NPNL N + S+P
Sbjct: 417 GDTSKLMKILQPQDVDLALDSGA-SLLHLAVEAGQEECAKWLL-LNNANPNLSNRRGSTP 474

Query: 359 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
           LH A       +V++LL   +   +  D+   + L+      QN  E + +LL E
Sbjct: 475 LHMAVERRVRGVVELLLAR-KISVNAKDEDQWTALHFA---AQNGDESSTRLLLE 525


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 40/108 (37%), Positives = 66/108 (61%), Gaps = 5/108 (4%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPNL 350
           LH +A  G  EL++ LL  + +V+  DS+   P+HYA W G++E  R+LL      N   
Sbjct: 53  LHHAALGGSLELIALLLEAQATVDIKDSNGMRPLHYAAWQGRLEPVRLLLRASAAVNAAS 112

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CE 397
           L+GQ+  PLH AA  GH E+ ++LL H +++  + ++  ++PL++ CE
Sbjct: 113 LDGQI--PLHLAAQYGHYEVSEMLLQH-QSNPCLVNKAKKTPLDLACE 157



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 31/86 (36%), Positives = 45/86 (52%), Gaps = 1/86 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A +G  E +  LL    +VN    D   P+H A  YG  E + +LL+  + NP L
Sbjct: 85  PLHYAAWQGRLEPVRLLLRASAAVNAASLDGQIPLHLAAQYGHYEVSEMLLQH-QSNPCL 143

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLN 376
           +N    +PL  A   G  ++ Q+LLN
Sbjct: 144 VNKAKKTPLDLACEFGRLKVAQLLLN 169



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 17/97 (17%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-------- 342
           PLH +A  G  E+   LL  + +   ++     P+  AC +G+++  ++LL         
Sbjct: 118 PLHLAAQYGHYEVSEMLLQHQSNPCLVNKAKKTPLDLACEFGRLKVAQLLLNSHLCVALL 177

Query: 343 ----KGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL 375
               K  C+PN      ++PLH AA  GH E+++ LL
Sbjct: 178 EGEAKDPCDPN-----YTTPLHLAAKNGHREVIRQLL 209



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 6/88 (6%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G  E++ +LL     +N+      A +H A  YGK E  R+LLE G  + N+
Sbjct: 192 PLHLAAKNGHREVIRQLLRAGIEINRQTKTGTA-LHEAALYGKTEVVRLLLE-GGVDVNI 249

Query: 351 LNGQLSSPL----HFAAGGGHAEIVQIL 374
            N    + L     F       EI Q+L
Sbjct: 250 RNTYNQTALDIVNQFTTSQASREIKQLL 277



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 333 KVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSP 392
           K   T++L    + N N  +    S LH AA GG  E++ +LL    T   I D  G  P
Sbjct: 27  KATKTKLLGSTKRLNVNYQDADGFSALHHAALGGSLELIALLLEAQAT-VDIKDSNGMRP 85

Query: 393 LN 394
           L+
Sbjct: 86  LH 87


>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
          Length = 2062

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 70/266 (26%), Positives = 116/266 (43%), Gaps = 19/266 (7%)

Query: 160 LDKWLDERHAQSHFIPALFRPSPLERIKTNV-INPAYATES-GQTENSLHMGYSALEIKS 217
           + K + E+ +    +P    PS  E   ++   +P + +E+ G+   S +  YS  E   
Sbjct: 48  VSKEMKEKSSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPE 107

Query: 218 KMLALEKADTCIYNP---LFGSDLQYTNRVD---KVVINPYFGLGAPDYSKIQIPKQEKW 271
           K    ++A      P   LFG  L    ++    ++          P++     P Q+K 
Sbjct: 108 KKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQTTPAQKKT 167

Query: 272 QRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYAC 329
             S SS  +DK  +R    + PLH +A  GD + +  L+S   +VN  D   W P+H AC
Sbjct: 168 PSS-SSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEAC 226

Query: 330 WYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQG 389
             G  +  +IL+  G  + N       +PLH +A  GH +IV++LL H        ++ G
Sbjct: 227 NVGYYDVAKILIAAG-ADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQ-ANKHG 284

Query: 390 RSPLNICEENKQNNWEEAAKLLKEAI 415
             P+++ E       EE   LLK  +
Sbjct: 285 ERPVDVAET------EELELLLKREV 304


>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
          Length = 2039

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 50/160 (31%), Positives = 77/160 (48%), Gaps = 11/160 (6%)

Query: 258 PDYSKIQIPKQEKWQRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVN 315
           P++     P Q+K   S SS  +DK  +R    + PLH +A  GD + +  L+S   +VN
Sbjct: 131 PNHPSQTTPAQKKTPSS-SSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVN 189

Query: 316 QLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL 375
             D   W P+H AC  G  +  +IL+  G  + N       +PLH +A  GH +IV++LL
Sbjct: 190 VKDFAGWTPLHEACNVGYYDVAKILIAAG-ADVNTQGLDDDTPLHDSASSGHRDIVKLLL 248

Query: 376 NHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
            H        ++ G  P+++ E       EE   LLK  +
Sbjct: 249 RHGGNPFQ-ANKHGERPVDVAET------EELELLLKREV 281


>gi|116534990 ankyrin-like protein 1 [Homo sapiens]
          Length = 1119

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 8/135 (5%)

Query: 287 VDDFPLHRSACEGDSELLSRLL--SERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG 344
           +D F LH +A EG  EL+ ++   S    ++++D     P+H A    ++E+ + LL +G
Sbjct: 62  MDTFFLHYAAAEGQIELMEKITRDSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRG 121

Query: 345 KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNN 403
             NPNL N  + +PLH A  G + E++++LL H   D ++  + G + + I C  N    
Sbjct: 122 -ANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNN--- 177

Query: 404 WEEAAKLLKEAINKP 418
             EA ++L +   KP
Sbjct: 178 -SEALQILLKKGAKP 191



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +G    ++ LL    S++    D  +P+H+A  YG++   + LL+       L
Sbjct: 416 PLHYACRQGGPGSVNNLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISDTRLL 475

Query: 351 LNGQL--SSPLHFAAGGGHAEIVQILL 375
             G L   +PLH AA  GH ++VQ+LL
Sbjct: 476 NEGDLHGMTPLHLAAKNGHDKVVQLLL 502



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 41/147 (27%), Positives = 71/147 (48%), Gaps = 15/147 (10%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G  +++ +LL ++ ++   D + W  +H+A   G  +  +++L+      + 
Sbjct: 485 PLHLAAKNGHDKVV-QLLLKKGALFLSDHNGWTALHHASMGGYTQTMKVILDTNLKCTDR 543

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ--------- 401
           L+   ++ LHFAA  GHA+ V +LL+H   D  +  QQ  S L++   NK+         
Sbjct: 544 LDEDGNTALHFAAREGHAKAVALLLSH-NADIVLNKQQA-SFLHLALHNKRKEVVLTIIR 601

Query: 402 -NNWEEAAKLLKEAINKPYEKVRIYRM 427
              W+E  K+     N P  K  I  M
Sbjct: 602 SKRWDECLKIFSH--NSPGNKCPITEM 626



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/106 (25%), Positives = 50/106 (47%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +   GD E++   L     ++ ++      IH+A   G  E  ++++     + ++
Sbjct: 242 PLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKLMISSYSGSVDI 301

Query: 351 LN---GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
           +N   G   + LH A+   H E+   L++    D +  D +GRSPL
Sbjct: 302 VNTTDGCHETMLHRASLFDHHELADYLIS-VGADINKIDSEGRSPL 346



 Score = 37.0 bits (84), Expect = 0.066
 Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 318 DSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
           D+D   P+HYAC  G   +   LL     + +  +    SPLHFAA  G     Q LL  
Sbjct: 410 DNDGCTPLHYACRQGGPGSVNNLL-GFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQD 468

Query: 378 PETDRHIT--DQQGRSPLNICEEN 399
               R +   D  G +PL++  +N
Sbjct: 469 ISDTRLLNEGDLHGMTPLHLAAKN 492



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 25/87 (28%), Positives = 41/87 (47%), Gaps = 11/87 (12%)

Query: 300 DSELLSRLLSERFSVNQLDSDHWA--PIHYACWYGKVEATRILLEKGK-------CNPNL 350
           +SE L  LL +        S+ W   PIH A + G  E   I+L  G+        + N 
Sbjct: 177 NSEALQILLKK--GAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHINF 234

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
           +N   ++PLH A   G  E++++ L++
Sbjct: 235 MNNGKATPLHLAVQNGDLEMIKMCLDN 261


>gi|50511945 cajalin 2 isoform a [Homo sapiens]
          Length = 1248

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 37/106 (34%), Positives = 57/106 (53%), Gaps = 3/106 (2%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP--N 349
           LH +A  G  +++ +LL    S N  D+  + PIH A W G VE  +IL+  G  +   N
Sbjct: 63  LHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKILIHHGPSHSRVN 122

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
             N +  + LH AA  GH+E+V +LL    TD  I + +  +PL++
Sbjct: 123 EQNNENETALHCAAQYGHSEVVAVLLEE-LTDPTIRNSKLETPLDL 167



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 30/93 (32%), Positives = 54/93 (58%), Gaps = 5/93 (5%)

Query: 290 FPLHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKC 346
           FP+H +A +GD E++  L+    S   VN+ ++++   +H A  YG  E   +LLE+   
Sbjct: 94  FPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEE-LT 152

Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLN-HP 378
           +P + N +L +PL  AA  G   +V+++++ HP
Sbjct: 153 DPTIRNSKLETPLDLAALYGRLRVVKMIISAHP 185



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 41/155 (26%), Positives = 66/155 (42%), Gaps = 36/155 (23%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G SE+++ LL E       +S    P+  A  YG++   ++++     +PNL+
Sbjct: 132 LHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMIIS---AHPNLM 188

Query: 352 --NGQLSSPLHFAAGGGHAEIVQILLN-------------------------------HP 378
             N +  +PLH AA  GH  +VQ+LL                                  
Sbjct: 189 SCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLET 248

Query: 379 ETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
             D +I D  GR+ L+I +E+      + A LL+E
Sbjct: 249 GIDANIKDSLGRTVLDILKEHPSQKSLQIATLLQE 283



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 3/112 (2%)

Query: 304 LSRLLS--ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHF 361
           LS LLS     +VN  DS  +  +H+A   G  +    LL+  + + N+ + +   P+H 
Sbjct: 40  LSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQY-EASTNVADNKGYFPIHL 98

Query: 362 AAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKE 413
           AA  G  EIV+IL++H  +   + +Q   +   +    +  + E  A LL+E
Sbjct: 99  AAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEE 150


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 40/129 (31%), Positives = 66/129 (51%), Gaps = 4/129 (3%)

Query: 269 EKWQRSMSSVTEDK--ERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
           +K   + +S T+DK  +R    +  LHR+A  GD+  +  L+SE   VN  D   W  +H
Sbjct: 147 QKGTPNSASKTKDKVNKRNERGETRLHRAAIRGDARRIKELISEGADVNVKDFAGWTALH 206

Query: 327 YACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITD 386
            AC  G  +  + LL  G    N       +PLH AA  GH ++V++LL +    +  ++
Sbjct: 207 EACNRGYYDVAKQLLAAG-AEVNTKGLDDDTPLHDAANNGHYKVVKLLLRYGGNPQQ-SN 264

Query: 387 QQGRSPLNI 395
           ++G +PL +
Sbjct: 265 RKGETPLKV 273


>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
           sapiens]
          Length = 226

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 40/122 (32%), Positives = 68/122 (55%), Gaps = 7/122 (5%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G  E++  LL +   VN ++ +   P+HYA    + E   +LLE G  NP+ 
Sbjct: 76  PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLE-GGANPDA 134

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNNWEEAAK 409
            +   ++ +H AA  G+ +++ ILL + +   +I D +G +PL++ C+E +     E AK
Sbjct: 135 KDHYEATAMHRAAAKGNLKMIHILLYY-KASTNIQDTEGNTPLHLACDEER----VEEAK 189

Query: 410 LL 411
           LL
Sbjct: 190 LL 191



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 8/129 (6%)

Query: 302 ELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHF 361
           EL   +L+++    + D D    +H+AC  G  E    LL+ G    N  +    SPLH 
Sbjct: 21  ELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLG-VPVNDKDDAGWSPLHI 79

Query: 362 AAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAINKP--- 418
           AA  G  EIV+ LL       +  +Q G +PL+      +N  E A  LL+   N     
Sbjct: 80  AASAGRDEIVKALLG-KGAQVNAVNQNGCTPLHYAA--SKNRHEIAVMLLEGGANPDAKD 136

Query: 419 -YEKVRIYR 426
            YE   ++R
Sbjct: 137 HYEATAMHR 145



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 23/74 (31%), Positives = 43/74 (58%), Gaps = 1/74 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           +HR+A +G+ +++  LL  + S N  D++   P+H AC   +VE  ++L+ +G  +  + 
Sbjct: 143 MHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQG-ASIYIE 201

Query: 352 NGQLSSPLHFAAGG 365
           N +  +PL  A GG
Sbjct: 202 NKEEKTPLQVAKGG 215



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 5/66 (7%)

Query: 332 GKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQIL--LNHPETDRHITDQQG 389
           GK+E  +  +   K      +    + LH+A   GH EIV+ L  L  P  D+   D  G
Sbjct: 17  GKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDK---DDAG 73

Query: 390 RSPLNI 395
            SPL+I
Sbjct: 74  WSPLHI 79


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +E+   LL  +  VN    D   P+H A   G     ++LLE    NPNL
Sbjct: 473 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 531

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH AA  GH E V  LL   E  +    ++G +PL++
Sbjct: 532 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 575



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG  E +  LL +  S   +    + P+H A  YGKV    +LLE+   +PN 
Sbjct: 539 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 597

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A    + +IV++LL    +  H     G +PL+I    KQN  E A  L
Sbjct: 598 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 654

Query: 411 LK 412
           L+
Sbjct: 655 LQ 656



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +    ++  LL    S++ +      P+H A + G +   + LL++G  +PN+
Sbjct: 407 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 465

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N ++ +PLH AA  GH E+ + LL +
Sbjct: 466 SNVKVETPLHMAARAGHTEVAKYLLQN 492



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A     + +  LL     ++ +  DH  P+H A   G     ++LL+KG K N  
Sbjct: 341 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 400

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            LNG   +PLH A    H  ++++LL    +   +T + G +PL++
Sbjct: 401 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 443



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W    PLH +A +   E+   LL    S N        P+H A   G  E   +LL K +
Sbjct: 633 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 691

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N NL N    +PLH  A  GH  +  +L+ H       T + G +PL++
Sbjct: 692 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 740



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A   +  +   LL+   SVN    +   P+H A   G V   R+LL++G      
Sbjct: 242 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 301

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
              +L +PLH AA  GH  I +ILL+H    +  T + G SP+++  +
Sbjct: 302 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 347



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +    + +++  LL    S +    + + P+H A    +VE  R LL+ G  + N 
Sbjct: 605 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 663

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            + Q  +PLH AA  GHAE+V +LL+  + + ++ ++ G +PL++
Sbjct: 664 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 707



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A EG   +   L+     V+      + P+H A  YG ++  + LL+  + + N 
Sbjct: 704 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 762

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
                 SPLH AA  GH +IV +LL +  +   ++   G +PL I +
Sbjct: 763 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 808



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG +E+++ LLS++ + N  +     P+H     G V    +L++ G    + 
Sbjct: 671 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 729

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A+  G+ ++V+ LL H + D +   + G SPL+  +  +Q + +    L
Sbjct: 730 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 786

Query: 411 LK 412
           LK
Sbjct: 787 LK 788



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH +A  G + ++  LL    + N   +    P+H A   G VE    LLEK + +
Sbjct: 503 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 561

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
              +  +  +PLH AA  G   + ++LL   E D H     + G +PL++
Sbjct: 562 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 608



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
           PLH ++  G+  ++  LL     +     D   P+H A   G V  + ILL+ G      
Sbjct: 275 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 334

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
             NG   SP+H AA G H + V++LL +
Sbjct: 335 TKNGL--SPIHMAAQGDHLDCVRLLLQY 360



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  L++   +VN      + P++ A     +E  + LLE G  N N+ 
Sbjct: 115 LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 173

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
                +PL  A   GH  +V  L+N+
Sbjct: 174 TEDGFTPLAVALQQGHENVVAHLINY 199



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH ++  G+ +L+  LL  +  VN      ++P+H A   G  +   +LL+ G  +PN 
Sbjct: 737 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 795

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
           ++   ++PL  A   G+  +  +L
Sbjct: 796 VSSDGTTPLAIAKRLGYISVTDVL 819



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A   D+   + LL    + + L    + P+H A  Y  +   ++LL +G  + N  
Sbjct: 210 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 268

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
                +PLH A+  G+  +V++LL+
Sbjct: 269 PQNGITPLHIASRRGNVIMVRLLLD 293


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +E+   LL  +  VN    D   P+H A   G     ++LLE    NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH AA  GH E V  LL   E  +    ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG  E +  LL +  S   +    + P+H A  YGKV    +LLE+   +PN 
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A    + +IV++LL    +  H     G +PL+I    KQN  E A  L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621

Query: 411 LK 412
           L+
Sbjct: 622 LQ 623



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +    ++  LL    S++ +      P+H A + G +   + LL++G  +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N ++ +PLH AA  GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A     + +  LL     ++ +  DH  P+H A   G     ++LL+KG K N  
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            LNG   +PLH A    H  ++++LL    +   +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W    PLH +A +   E+   LL    S N        P+H A   G  E   +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N NL N    +PLH  A  GH  +  +L+ H       T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A   +  +   LL+   SVN    +   P+H A   G V   R+LL++G      
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
              +L +PLH AA  GH  I +ILL+H    +  T + G SP+++  +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +    + +++  LL    S +    + + P+H A    +VE  R LL+ G  + N 
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            + Q  +PLH AA  GHAE+V +LL+  + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A EG   +   L+     V+      + P+H A  YG ++  + LL+  + + N 
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
                 SPLH AA  GH +IV +LL +  +   ++   G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG +E+++ LLS++ + N  +     P+H     G V    +L++ G    + 
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A+  G+ ++V+ LL H + D +   + G SPL+  +  +Q + +    L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753

Query: 411 LK 412
           LK
Sbjct: 754 LK 755



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH +A  G + ++  LL    + N   +    P+H A   G VE    LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
              +  +  +PLH AA  G   + ++LL   E D H     + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
           PLH ++  G+  ++  LL     +     D   P+H A   G V  + ILL+ G      
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
             NG   SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  L++   +VN      + P++ A     +E  + LLE G  N N+ 
Sbjct: 82  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
                +PL  A   GH  +V  L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH ++  G+ +L+  LL  +  VN      ++P+H A   G  +   +LL+ G  +PN 
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
           ++   ++PL  A   G+  +  +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A   D+   + LL    + + L    + P+H A  Y  +   ++LL +G  + N  
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
                +PLH A+  G+  +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +E+   LL  +  VN    D   P+H A   G     ++LLE    NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH AA  GH E V  LL   E  +    ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG  E +  LL +  S   +    + P+H A  YGKV    +LLE+   +PN 
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A    + +IV++LL    +  H     G +PL+I    KQN  E A  L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621

Query: 411 LK 412
           L+
Sbjct: 622 LQ 623



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +    ++  LL    S++ +      P+H A + G +   + LL++G  +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N ++ +PLH AA  GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A     + +  LL     ++ +  DH  P+H A   G     ++LL+KG K N  
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            LNG   +PLH A    H  ++++LL    +   +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W    PLH +A +   E+   LL    S N        P+H A   G  E   +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N NL N    +PLH  A  GH  +  +L+ H       T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A   +  +   LL+   SVN    +   P+H A   G V   R+LL++G      
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
              +L +PLH AA  GH  I +ILL+H    +  T + G SP+++  +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +    + +++  LL    S +    + + P+H A    +VE  R LL+ G  + N 
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            + Q  +PLH AA  GHAE+V +LL+  + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A EG   +   L+     V+      + P+H A  YG ++  + LL+  + + N 
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
                 SPLH AA  GH +IV +LL +  +   ++   G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG +E+++ LLS++ + N  +     P+H     G V    +L++ G    + 
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A+  G+ ++V+ LL H + D +   + G SPL+  +  +Q + +    L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753

Query: 411 LK 412
           LK
Sbjct: 754 LK 755



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH +A  G + ++  LL    + N   +    P+H A   G VE    LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
              +  +  +PLH AA  G   + ++LL   E D H     + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
           PLH ++  G+  ++  LL     +     D   P+H A   G V  + ILL+ G      
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
             NG   SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  L++   +VN      + P++ A     +E  + LLE G  N N+ 
Sbjct: 82  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
                +PL  A   GH  +V  L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH ++  G+ +L+  LL  +  VN      ++P+H A   G  +   +LL+ G  +PN 
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
           ++   ++PL  A   G+  +  +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A   D+   + LL    + + L    + P+H A  Y  +   ++LL +G  + N  
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
                +PLH A+  G+  +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +E+   LL  +  VN    D   P+H A   G     ++LLE    NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH AA  GH E V  LL   E  +    ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG  E +  LL +  S   +    + P+H A  YGKV    +LLE+   +PN 
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A    + +IV++LL    +  H     G +PL+I    KQN  E A  L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621

Query: 411 LK 412
           L+
Sbjct: 622 LQ 623



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +    ++  LL    S++ +      P+H A + G +   + LL++G  +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N ++ +PLH AA  GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A     + +  LL     ++ +  DH  P+H A   G     ++LL+KG K N  
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            LNG   +PLH A    H  ++++LL    +   +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W    PLH +A +   E+   LL    S N        P+H A   G  E   +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N NL N    +PLH  A  GH  +  +L+ H       T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A   +  +   LL+   SVN    +   P+H A   G V   R+LL++G      
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
              +L +PLH AA  GH  I +ILL+H    +  T + G SP+++  +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +    + +++  LL    S +    + + P+H A    +VE  R LL+ G  + N 
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            + Q  +PLH AA  GHAE+V +LL+  + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A EG   +   L+     V+      + P+H A  YG ++  + LL+  + + N 
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
                 SPLH AA  GH +IV +LL +  +   ++   G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG +E+++ LLS++ + N  +     P+H     G V    +L++ G    + 
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A+  G+ ++V+ LL H + D +   + G SPL+  +  +Q + +    L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753

Query: 411 LK 412
           LK
Sbjct: 754 LK 755



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH +A  G + ++  LL    + N   +    P+H A   G VE    LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
              +  +  +PLH AA  G   + ++LL   E D H     + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
           PLH ++  G+  ++  LL     +     D   P+H A   G V  + ILL+ G      
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
             NG   SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  L++   +VN      + P++ A     +E  + LLE G  N N+ 
Sbjct: 82  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
                +PL  A   GH  +V  L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH ++  G+ +L+  LL  +  VN      ++P+H A   G  +   +LL+ G  +PN 
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
           ++   ++PL  A   G+  +  +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A   D+   + LL    + + L    + P+H A  Y  +   ++LL +G  + N  
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
                +PLH A+  G+  +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 37/105 (35%), Positives = 51/105 (48%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G +E+   LL  +  VN    D   P+H A   G     ++LLE    NPNL
Sbjct: 440 PLHMAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLE-NNANPNL 498

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH AA  GH E V  LL   E  +    ++G +PL++
Sbjct: 499 ATTAGHTPLHIAAREGHVETVLALL-EKEASQACMTKKGFTPLHV 542



 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 42/122 (34%), Positives = 60/122 (49%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG  E +  LL +  S   +    + P+H A  YGKV    +LLE+   +PN 
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLER-DAHPNA 564

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A    + +IV++LL    +  H     G +PL+I    KQN  E A  L
Sbjct: 565 AGKNGLTPLHVAVHHNNLDIVKLLLPRGGSP-HSPAWNGYTPLHIAA--KQNQVEVARSL 621

Query: 411 LK 412
           L+
Sbjct: 622 LQ 623



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 26/87 (29%), Positives = 47/87 (54%), Gaps = 1/87 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +    ++  LL    S++ +      P+H A + G +   + LL++G  +PN+
Sbjct: 374 PLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRG-ASPNV 432

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N ++ +PLH AA  GH E+ + LL +
Sbjct: 433 SNVKVETPLHMAARAGHTEVAKYLLQN 459



 Score = 50.1 bits (118), Expect = 8e-06
 Identities = 31/106 (29%), Positives = 53/106 (50%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A     + +  LL     ++ +  DH  P+H A   G     ++LL+KG K N  
Sbjct: 308 PIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSR 367

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            LNG   +PLH A    H  ++++LL    +   +T + G +PL++
Sbjct: 368 ALNG--FTPLHIACKKNHVRVMELLLKTGASIDAVT-ESGLTPLHV 410



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 2/110 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W    PLH +A +   E+   LL    S N        P+H A   G  E   +LL K +
Sbjct: 600 WNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK-Q 658

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N NL N    +PLH  A  GH  +  +L+ H       T + G +PL++
Sbjct: 659 ANGNLGNKSGLTPLHLVAQEGHVPVADVLIKH-GVMVDATTRMGYTPLHV 707



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 35/108 (32%), Positives = 54/108 (50%), Gaps = 2/108 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A   +  +   LL+   SVN    +   P+H A   G V   R+LL++G      
Sbjct: 209 PLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETK 268

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEE 398
              +L +PLH AA  GH  I +ILL+H    +  T + G SP+++  +
Sbjct: 269 TKDEL-TPLHCAARNGHVRISEILLDHGAPIQAKT-KNGLSPIHMAAQ 314



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/105 (30%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +    + +++  LL    S +    + + P+H A    +VE  R LL+ G  + N 
Sbjct: 572 PLHVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGG-SANA 630

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            + Q  +PLH AA  GHAE+V +LL+  + + ++ ++ G +PL++
Sbjct: 631 ESVQGVTPLHLAAQEGHAEMVALLLS-KQANGNLGNKSGLTPLHL 674



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 2/107 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A EG   +   L+     V+      + P+H A  YG ++  + LL+  + + N 
Sbjct: 671 PLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNA 729

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICE 397
                 SPLH AA  GH +IV +LL +  +   ++   G +PL I +
Sbjct: 730 KTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVS-SDGTTPLAIAK 775



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 63/122 (51%), Gaps = 4/122 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG +E+++ LLS++ + N  +     P+H     G V    +L++ G    + 
Sbjct: 638 PLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHG-VMVDA 696

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH A+  G+ ++V+ LL H + D +   + G SPL+  +  +Q + +    L
Sbjct: 697 TTRMGYTPLHVASHYGNIKLVKFLLQH-QADVNAKTKLGYSPLH--QAAQQGHTDIVTLL 753

Query: 411 LK 412
           LK
Sbjct: 754 LK 755



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 33/110 (30%), Positives = 52/110 (47%), Gaps = 6/110 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH +A  G + ++  LL    + N   +    P+H A   G VE    LLEK + +
Sbjct: 470 DQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLALLEK-EAS 528

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH--ITDQQGRSPLNI 395
              +  +  +PLH AA  G   + ++LL   E D H     + G +PL++
Sbjct: 529 QACMTKKGFTPLHVAAKYGKVRVAELLL---ERDAHPNAAGKNGLTPLHV 575



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 3/88 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK-CNPN 349
           PLH ++  G+  ++  LL     +     D   P+H A   G V  + ILL+ G      
Sbjct: 242 PLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAK 301

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNH 377
             NG   SP+H AA G H + V++LL +
Sbjct: 302 TKNGL--SPIHMAAQGDHLDCVRLLLQY 327



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  L++   +VN      + P++ A     +E  + LLE G  N N+ 
Sbjct: 82  LHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENG-ANQNVA 140

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNH 377
                +PL  A   GH  +V  L+N+
Sbjct: 141 TEDGFTPLAVALQQGHENVVAHLINY 166



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 23/84 (27%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH ++  G+ +L+  LL  +  VN      ++P+H A   G  +   +LL+ G  +PN 
Sbjct: 704 PLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNG-ASPNE 762

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
           ++   ++PL  A   G+  +  +L
Sbjct: 763 VSSDGTTPLAIAKRLGYISVTDVL 786



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A   D+   + LL    + + L    + P+H A  Y  +   ++LL +G  + N  
Sbjct: 177 LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG-ASVNFT 235

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLN 376
                +PLH A+  G+  +V++LL+
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLD 260


>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
          Length = 1429

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 34/108 (31%), Positives = 57/108 (52%), Gaps = 2/108 (1%)

Query: 292  LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
            LH S  +G  E++  L++    VN  D++  + +  A W G V+  ++L+E G    +  
Sbjct: 983  LHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTC 1042

Query: 352  NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEEN 399
            N Q ++ L  AA  GH ++VQ+LL H     H  DQ GR+ + +  +N
Sbjct: 1043 N-QGATALCIAAQEGHIDVVQVLLEHGADPNH-ADQFGRTAMRVAAKN 1088



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 2/103 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PL  +A +G +++++ L+    ++N  D D W  +  A W G  E    LL  G    + 
Sbjct: 581 PLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAG-VKVDC 639

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
            +    + L  AA GGH +IV  LL H   + +  D +GR+ L
Sbjct: 640 ADADSRTALRAAAWGGHEDIVLNLLQH-GAEVNKADNEGRTAL 681



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 34/105 (32%), Positives = 50/105 (47%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A EG   +   L+ +    N++D+D   P   A   G  +  +ILLE  K N + 
Sbjct: 850 PLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLE-NKSNIDQ 908

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 + L  AA  GH +IV++L +H   D +  D  GR  L I
Sbjct: 909 RGYDGRNALRVAALEGHRDIVELLFSH-GADVNCKDADGRPTLYI 952



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 36/122 (29%), Positives = 58/122 (47%), Gaps = 4/122 (3%)

Query: 296 ACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQL 355
           A +G + ++S L+     V+  D D   P+  A + G V+   +LLE G  + +  +   
Sbjct: 723 ASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLE-GGADVDHTDNNG 781

Query: 356 SSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
            +PL  AA  GHA +V  LL        I D +GR+ L+I   + Q N E    LL   +
Sbjct: 782 RTPLLAAASMGHASVVNTLLFWGAAVDSI-DSEGRTVLSIA--SAQGNVEVVRTLLDRGL 838

Query: 416 NK 417
           ++
Sbjct: 839 DE 840



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 33/104 (31%), Positives = 50/104 (48%), Gaps = 2/104 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           L  +A  G +E++S LL     V+  D+D    +  A W G  +    LL+ G    N  
Sbjct: 615 LRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHG-AEVNKA 673

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
           + +  + L  AA  GH EIV+ LL+H     H  D  GR+ L++
Sbjct: 674 DNEGRTALIAAAYMGHREIVEHLLDHGAEVNH-EDVDGRTALSV 716



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/126 (28%), Positives = 57/126 (45%), Gaps = 10/126 (7%)

Query: 271 WQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACW 330
           W  ++ S+  D E + V    L  ++ +G+ E++  LL      N  D   W P+H A +
Sbjct: 803 WGAAVDSI--DSEGRTV----LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF 856

Query: 331 YGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILL-NHPETDRHITDQQG 389
            G       L+E+G    N ++     P   A+  GH + VQILL N    D+   D  G
Sbjct: 857 EGHRLICEALIEQG-ARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYD--G 913

Query: 390 RSPLNI 395
           R+ L +
Sbjct: 914 RNALRV 919



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 3/100 (3%)

Query: 294 RSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNG 353
           R A E +  + + LL    SVNQ DS+    +  A + G ++   +L+ +G  +  + + 
Sbjct: 519 RQALEREDSIRT-LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRG-ADLEIEDA 576

Query: 354 QLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
              +PL  AA  GH ++V  L+       H TDQ G + L
Sbjct: 577 HGHTPLTLAARQGHTKVVNCLIGCGANINH-TDQDGWTAL 615



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 27/102 (26%), Positives = 46/102 (45%), Gaps = 2/102 (1%)

Query: 292  LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
            L  +A EG  +++  L S    VN  D+D    ++      ++      LE G  N    
Sbjct: 917  LRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENG-ANVEAS 975

Query: 352  NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
            + +  + LH +   GH E+VQ+L+ +   D +  D + RS L
Sbjct: 976  DAEGRTALHVSCWQGHMEMVQVLIAY-HADVNAADNEKRSAL 1016


>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
          Length = 1076

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 38/129 (29%), Positives = 66/129 (51%), Gaps = 2/129 (1%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PL ++    D E +  LLS++ ++N LD +   P+H A + G V   ++LL  G  N
Sbjct: 8   DQPPLVQAIFSRDVEEVRSLLSQKENINVLDQERRTPLHAAAYVGDVPILQLLLMSG-AN 66

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEA 407
            N  +    +PLH AA   + +++ +LL H   D +  D+  ++PL++   N+     EA
Sbjct: 67  VNAKDTLWLTPLHRAAASRNEKVLGLLLAH-SADVNARDKLWQTPLHVAAANRATKCAEA 125

Query: 408 AKLLKEAIN 416
              L  ++N
Sbjct: 126 LAPLLSSLN 134



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 3/86 (3%)

Query: 317  LDSDHWAPIHYACWYGKVEATRILLEKGKCNP--NLLNGQLSSPLHFAAGGGHAEIVQIL 374
            LD +    +H AC  G  +   ++L + +     N  N  L  PLH AA  G A +VQ L
Sbjct: 921  LDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSALQMPLHIAARNGLASVVQAL 980

Query: 375  LNHPETDRHITDQQGRSPLNICEENK 400
            L+H  T   + D++G +P   C  NK
Sbjct: 981  LSHGATVLAV-DEEGHTPALACAPNK 1005



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 4/113 (3%)

Query: 282 KERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILL 341
           K+  W+   PLHR+A   + ++L  LL+    VN  D     P+H A      +    L 
Sbjct: 70  KDTLWLT--PLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALA 127

Query: 342 EKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
                + N+ +    S LH A   GH E V +LLN      ++ D++ R PL+
Sbjct: 128 PL-LSSLNVADRSGRSALHHAVHSGHLETVNLLLN-KGASLNVCDKKERQPLH 178



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A    ++    L     S+N  D    + +H+A   G +E   +LL KG  + N+
Sbjct: 110 PLHVAAANRATKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKG-ASLNV 168

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILL 375
            + +   PLH+AA  GH E++++L+
Sbjct: 169 CDKKERQPLHWAAFLGHLEVLKLLV 193



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 1/104 (0%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  E++  LL     +++ ++     +H AC+ G+ +A  I L     N N  
Sbjct: 210 LHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIACYLGQ-DAVAIELVNAGANVNQP 268

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
           N +  +PLH AA   +  +   LL +   D +   ++G+SPL++
Sbjct: 269 NDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHM 312



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +   G  E ++ LL++  S+N  D     P+H+A + G +E  ++L+ +G  +    
Sbjct: 144 LHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG-ADLGCK 202

Query: 352 NGQLSSPLHFAAGGGHAEIVQILL 375
           + +    LH AA  G  E+V+ LL
Sbjct: 203 DRKGYGLLHTAAASGQIEVVKYLL 226



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 40/150 (26%), Positives = 65/150 (43%), Gaps = 21/150 (14%)

Query: 270 KWQRSMSSVTEDKERQWVDDF---PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
           ++ RS   +    E    D F   PLH +A  G   L+S L++      +       P+H
Sbjct: 318 RFTRSQILIQNGSEIDCADKFGNTPLHVAARYGHELLISTLMTNGADTARRGIHDMFPLH 377

Query: 327 YACWYGKVEATRILLEKGK--------CNPNLLNG--QLSSP-------LHFAAGGGHAE 369
            A  +G  +  R LL  G+         N ++L+    +++P       LH AA GG+ E
Sbjct: 378 LAVLFGFSDCCRKLLSSGQLYSIVSSLSNEHVLSAGFDINTPDNLGRTCLHAAASGGNVE 437

Query: 370 IVQILLNHPETDRHITDQQGRSPLNICEEN 399
            + +LL+    D    D+ GR+PL+    N
Sbjct: 438 CLNLLLS-SGADLRRRDKFGRTPLHYAAAN 466



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/137 (27%), Positives = 57/137 (41%), Gaps = 8/137 (5%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KC 346
           +D PL  S  +     L  LL      +  D   +  +HYA  YG  +   +LLE    C
Sbjct: 517 EDEPLKESRRKEAFFCLEFLLDNGADPSLRDRQGYTAVHYAAAYGNRQNLELLLEMSFNC 576

Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEE 406
             ++ +    SPLH AA  GH E ++ L      +  + D +GR+ L +  E       E
Sbjct: 577 LEDVESTIPVSPLHLAAYNGHCEALKTLA-ETLVNLDVRDHKGRTALFLATERGSTECVE 635

Query: 407 ------AAKLLKEAINK 417
                 A+ L+KE   K
Sbjct: 636 VLTAHGASALIKERKRK 652



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/124 (28%), Positives = 64/124 (51%), Gaps = 10/124 (8%)

Query: 276 SSVTEDKERQWVDDFPLHRSACEGDSELLSRLLS--ERFSVNQ-LDSDHWAPIHYACWYG 332
           S++ ++++R+W    PLH +A  G ++ L  L+   ER  +   +D+    P+  A   G
Sbjct: 643 SALIKERKRKWT---PLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNG 699

Query: 333 KVEATRILLEKGK-CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRS 391
            V+   +LLEKG   +   L G+  + LH  A  G  + +  LL+H +      D +GR+
Sbjct: 700 HVDCVHLLLEKGSTADAADLRGR--TALHRGAVTGCEDCLAALLDH-DAFVLCRDFKGRT 756

Query: 392 PLNI 395
           P+++
Sbjct: 757 PIHL 760



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 29/89 (32%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LHR A  G  + L+ LL     V   D     PIH A   G     R LL+       L 
Sbjct: 725 LHRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACGHTAVLRTLLQAALSTDPLD 784

Query: 352 NG---QLSSPLHFAAGGGHAEIVQILLNH 377
            G      SP+H+A+  GH + +++LL H
Sbjct: 785 AGVDYSGYSPMHWASYTGHEDCLELLLEH 813



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 7/109 (6%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDS----DHWAPIHYACWYGKVEATRILLEKGKC 346
           P+H ++  G + +L  LL    S + LD+      ++P+H+A + G  +   +LLE    
Sbjct: 757 PIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLLEHSPF 816

Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETD-RHITDQQGRSPLN 394
             + L G   +PLH A         ++LL        +  D +GR+PL+
Sbjct: 817 --SYLEGNPFTPLHCAVINNQDSTTEMLLGALGAKIVNSRDAKGRTPLH 863



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 6/113 (5%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G  E L  L     +++  D      +  A   G  E   +L   G      
Sbjct: 588 PLHLAAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIK 647

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPE----TDRHITDQQGRSPLNICEEN 399
              +  +PLH AA  GH + + +L++  E    TD  + D  G++PL +   N
Sbjct: 648 ERKRKWTPLHAAAASGHTDSLHLLIDSGERADITD--VMDAYGQTPLMLAIMN 698



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G+ E L+ LLS    + + D     P+HYA   G  +    L+  G    N  
Sbjct: 427 LHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAG-AGVNEA 485

Query: 352 NGQLSSPLHFAA 363
           + +  SPLH+AA
Sbjct: 486 DCKGCSPLHYAA 497



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 38/169 (22%), Positives = 67/169 (39%), Gaps = 31/169 (18%)

Query: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYAC---WY 331
           +SS  + + R      PLH +A  G  +    L++    VN+ D    +P+HYA     Y
Sbjct: 443 LSSGADLRRRDKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLHYAAASDTY 502

Query: 332 GKVE-------------------------ATRILLEKGKCNPNLLNGQLSSPLHFAAGGG 366
            + E                             LL+ G  +P+L + Q  + +H+AA  G
Sbjct: 503 RRAEPHTPSSHDAEEDEPLKESRRKEAFFCLEFLLDNG-ADPSLRDRQGYTAVHYAAAYG 561

Query: 367 HAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAI 415
           + + +++LL    +   + D +   P++       N   EA K L E +
Sbjct: 562 NRQNLELLLE--MSFNCLEDVESTIPVSPLHLAAYNGHCEALKTLAETL 608



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 30/105 (28%), Positives = 46/105 (43%), Gaps = 3/105 (2%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +   G   +   L++   +VNQ +   + P+H A           LL     + N  
Sbjct: 243 LHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGADVNYQ 302

Query: 352 NGQLSSPLHFAAGGGHAEIVQILL-NHPETDRHITDQQGRSPLNI 395
           + +  SPLH AA  G     QIL+ N  E D    D+ G +PL++
Sbjct: 303 SKEGKSPLHMAAIHGRFTRSQILIQNGSEID--CADKFGNTPLHV 345


>gi|140161500 ankyrin repeat and sterile alpha motif domain
           containing 1 [Homo sapiens]
          Length = 1134

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 33/93 (35%), Positives = 57/93 (61%), Gaps = 5/93 (5%)

Query: 290 FPLHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKC 346
           +PLH +A +GD++++  L+ +  S   VN+ ++D+   +H A  YG  E  ++LLE+   
Sbjct: 115 YPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEE-LT 173

Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLN-HP 378
           +P + N +  +PL  AA  G  E+V++LLN HP
Sbjct: 174 DPTMRNNKFETPLDLAALYGRLEVVKMLLNAHP 206



 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 3/107 (2%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP-- 348
           PLH +A  G  +++  LL      N  DS    P+H A W G  +  R+L+ +G  +   
Sbjct: 83  PLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRV 142

Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
           N  N    + LH AA  GH E+V++LL    TD  + + +  +PL++
Sbjct: 143 NEQNNDNETALHCAAQYGHTEVVKVLLEE-LTDPTMRNNKFETPLDL 188



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 34/102 (33%), Positives = 54/102 (52%), Gaps = 5/102 (4%)

Query: 277 SVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEA 336
           S T   E+   ++  LH +A  G +E++  LL E       ++    P+  A  YG++E 
Sbjct: 138 SHTRVNEQNNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEV 197

Query: 337 TRILLEKGKCNPNLL--NGQLSSPLHFAAGGGHAEIVQILLN 376
            ++LL     +PNLL  N +  +PLH AA  GH  +VQ+LL+
Sbjct: 198 VKMLL---NAHPNLLSCNTKKHTPLHLAARNGHKAVVQVLLD 236



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%)

Query: 275 MSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKV 334
           +  +T+   R    + PL  +A  G  E++  LL+   ++   ++    P+H A   G  
Sbjct: 169 LEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCNTKKHTPLHLAARNGHK 228

Query: 335 EATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
              ++LL+ G    +    ++ S LH AA  G  ++VQILL    TD +I D  G + L+
Sbjct: 229 AVVQVLLDAGM--DSNYQTEMGSALHEAALFGKTDVVQILL-AAGTDVNIKDNHGLTALD 285

Query: 395 ICEENKQNNWEEAAKLLKE 413
              E      ++ A L+++
Sbjct: 286 TVRELPSQKSQQIAALIED 304



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 35/121 (28%), Positives = 58/121 (47%), Gaps = 6/121 (4%)

Query: 301 SELLSRLLS--ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSP 358
           S  LS LLS     +VN +DS  + P+H+A   G  +   +LL +     N+ + +   P
Sbjct: 58  SHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLL-RNDALTNVADSKGCYP 116

Query: 359 LHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENKQNNWEEAAKLLKEAINK 417
           LH AA  G A+IV++L++   +   + +Q   +   + C    Q    E  K+L E +  
Sbjct: 117 LHLAAWKGDAQIVRLLIHQGPSHTRVNEQNNDNETALHCA--AQYGHTEVVKVLLEELTD 174

Query: 418 P 418
           P
Sbjct: 175 P 175



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 10/106 (9%)

Query: 347 NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEE 406
           N N ++    +PLH AA  GH ++V++LL + +   ++ D +G  PL++        W+ 
Sbjct: 72  NVNCVDSTGYTPLHHAALNGHKDVVEVLLRN-DALTNVADSKGCYPLHLAA------WKG 124

Query: 407 AAKLLKEAINKPYEKVRIYRMDGSYRSV---ELKHGNNTTVQQIME 449
            A++++  I++     R+   +    +      ++G+   V+ ++E
Sbjct: 125 DAQIVRLLIHQGPSHTRVNEQNNDNETALHCAAQYGHTEVVKVLLE 170


>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
          Length = 4377

 Score = 57.4 bits (137), Expect = 5e-08
 Identities = 45/160 (28%), Positives = 73/160 (45%), Gaps = 10/160 (6%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH SA EG  ++ + LL    S++      + P+H A  YGK+E   +LL+K   +P+ 
Sbjct: 535 PLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQK-SASPDA 593

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKL 410
                 +PLH AA   + ++  +LL+   +  H   + G +PL+I    K+N  + A  L
Sbjct: 594 AGKSGLTPLHVAAHYDNQKVALLLLDQGASP-HAAAKNGYTPLHIAA--KKNQMDIATTL 650

Query: 411 LK------EAINKPYEKVRIYRMDGSYRSVELKHGNNTTV 444
           L+          +    V +   +G    V L  G N  V
Sbjct: 651 LEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANV 690



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 36/123 (29%), Positives = 62/123 (50%), Gaps = 4/123 (3%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G +E++  L+ +   V     D   P+H +   GK +  + LL++G  +PN  
Sbjct: 470 LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQG-ASPNAA 528

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
                +PLH +A  GH ++   LL+H      IT ++G +PL++    K    E A  LL
Sbjct: 529 TTSGYTPLHLSAREGHEDVAAFLLDH-GASLSITTKKGFTPLHVAA--KYGKLEVANLLL 585

Query: 412 KEA 414
           +++
Sbjct: 586 QKS 588



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 29/96 (30%), Positives = 46/96 (47%), Gaps = 3/96 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPN 349
           PLH +A E    +   L+++   V+      + P+H  C YG ++    LL+   K N  
Sbjct: 700 PLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAK 759

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT 385
             NG   +PLH AA  GH  I+ +LL +  +   +T
Sbjct: 760 TKNGY--TPLHQAAQQGHTHIINVLLQNNASPNELT 793



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 39/159 (24%), Positives = 72/159 (45%), Gaps = 10/159 (6%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH ++ EG  E++S LL    +V+         +H A   G+ E  ++L+  G  N N  
Sbjct: 78  LHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNG-ANVNAQ 136

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
           +    +PL+ AA   H E+V+ LL++    + +  + G +PL +     Q   ++   LL
Sbjct: 137 SQNGFTPLYMAAQENHLEVVKFLLDN-GASQSLATEDGFTPLAVA---LQQGHDQVVSLL 192

Query: 412 -----KEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQ 445
                K  +  P   +   + D    ++ L++ NN  V+
Sbjct: 193 LENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVE 231



 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 6/107 (5%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPN- 349
           PLH +        +  LL     V+ + +D+   +H A   G  +  ++LL+K K NPN 
Sbjct: 337 PLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDK-KANPNA 395

Query: 350 -LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
             LNG   +PLH A      +++++LL H  + + +T + G +P+++
Sbjct: 396 KALNG--FTPLHIACKKNRIKVMELLLKHGASIQAVT-ESGLTPIHV 439



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 32/114 (28%), Positives = 57/114 (50%), Gaps = 4/114 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           PLH +A  G+  + + LL+   +V+    +   P+H A   G     ++LL++G K +  
Sbjct: 238 PLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGAKIDAK 297

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNN 403
             +G   +PLH  A  GH ++V++LL+        T + G SPL++  +    N
Sbjct: 298 TRDG--LTPLHCGARSGHEQVVEMLLDRAAPILSKT-KNGLSPLHMATQGDHLN 348



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 11/113 (9%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +  +   +++  LL    S+  +      PIH A + G V     L+  G  +PN 
Sbjct: 403 PLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHG-ASPNT 461

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILL----------NHPETDRHITDQQGRSPL 393
            N +  + LH AA  G AE+V+ L+             +T  HI+ + G++ +
Sbjct: 462 TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADI 514



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/110 (26%), Positives = 56/110 (50%), Gaps = 2/110 (1%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A  G  ++   LL ++ + N    + + P+H AC   +++   +LL+ G     + 
Sbjct: 371 LHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVT 430

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
              L +P+H AA  GH  IV  L++H  +  + T+ +G + L++   + Q
Sbjct: 431 ESGL-TPIHVAAFMGHVNIVSQLMHHGASP-NTTNVRGETALHMAARSGQ 478



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 1/90 (1%)

Query: 288 DDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           D  PLH ++  G++ ++  LL     ++    D   P+H     G  +   +LL++    
Sbjct: 268 DITPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPI 327

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
            +     LS PLH A  G H   VQ+LL H
Sbjct: 328 LSKTKNGLS-PLHMATQGDHLNCVQLLLQH 356



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 26/117 (22%), Positives = 56/117 (47%), Gaps = 1/117 (0%)

Query: 260 YSKIQIPKQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDS 319
           ++ + +  Q+   + +S + E+  +  V    LH +A + D++  + LL    + +    
Sbjct: 174 FTPLAVALQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADVESK 233

Query: 320 DHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
             + P+H A  YG +    +LL +           + +PLH A+  G+A +V++LL+
Sbjct: 234 SGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDI-TPLHVASKRGNANMVKLLLD 289



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 3/111 (2%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH  A  G  +++  LL     +     +  +P+H A     +   ++LL+      ++
Sbjct: 304 PLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDV 363

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI-CEENK 400
            N  L++ LH AA  GH ++ ++LL+  + + +     G +PL+I C++N+
Sbjct: 364 TNDYLTA-LHVAAHCGHYKVAKVLLD-KKANPNAKALNGFTPLHIACKKNR 412



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG-KCNPN 349
           P+H +A  G   ++S+L+    S N  +      +H A   G+ E  R L++ G +    
Sbjct: 436 PIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAK 495

Query: 350 LLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
             + Q  +PLH +A  G A+IVQ LL    +    T   G +PL++
Sbjct: 496 AKDDQ--TPLHISARLGKADIVQQLLQQGASPNAAT-TSGYTPLHL 538


>gi|187608777 NF-kappa-B inhibitor-like protein 2 [Homo sapiens]
          Length = 1378

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 13/134 (9%)

Query: 267 KQEKWQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
           K  KW R          R  + +  LHR+  EG    +  L+ +   +N  D   W P+H
Sbjct: 518 KGSKWNR----------RNDMGETLLHRACIEGQLRRVQDLVRQGHPLNPRDYCGWTPLH 567

Query: 327 YACWYGKVEATRILLEKGKC--NPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHI 384
            AC YG +E  R LL+ G    +P     +  +PLH A   GH E+ ++LL    +   +
Sbjct: 568 EACNYGHLEIVRFLLDHGAAVDDPGGQGCEGITPLHDALNCGHFEVAELLLERGASVT-L 626

Query: 385 TDQQGRSPLNICEE 398
             ++G SPL   ++
Sbjct: 627 RTRKGLSPLETLQQ 640


>gi|24233530 ankyrin repeat domain 44 [Homo sapiens]
          Length = 919

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 47/182 (25%), Positives = 82/182 (45%), Gaps = 11/182 (6%)

Query: 282 KERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILL 341
           +++ W    PLH +A     +    ++    SVN  D      +H+A   G VE   +LL
Sbjct: 78  RDKNW--QTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 135

Query: 342 EKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
            KG  N N  + +    LH+AA  GH ++V +L+NH   +    D++G +PL+    N Q
Sbjct: 136 AKG-ANINAFDKKDRRALHWAAYMGHLDVVALLINH-GAEVTCKDKKGYTPLHAAASNGQ 193

Query: 402 NNWEEAAKLLKEAINKPYEKVRIYRMDGSYRSVELKHGNNTTVQQIME-GMRLSQETQQY 460
            N      ++K  +N   E   I     +   +   +G +  V ++++ G  ++Q     
Sbjct: 194 IN------VVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNG 247

Query: 461 FT 462
           FT
Sbjct: 248 FT 249



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 31/105 (29%), Positives = 53/105 (50%), Gaps = 1/105 (0%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G   ++  LL+    +++++      +H AC+ G+      L++ G  N N 
Sbjct: 184 PLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYG-ANVNQ 242

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
            N    +PLHFAA   H  +   LL +   D +I  + G+SPL++
Sbjct: 243 PNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHM 287



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 2/110 (1%)

Query: 307 LLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGG 366
           L+ +   VN LDS+   P+H A + G  E   +L+  G    N  +    +PLH A    
Sbjct: 2   LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSG-ARVNAKDNMWLTPLHRAVASR 60

Query: 367 HAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLLKEAIN 416
             E VQ+L+ H   D +  D+  ++PL++   NK     E    L  ++N
Sbjct: 61  SEEAVQVLIKH-SADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVN 109



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 6/107 (5%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQL---DSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           PLH +A  G +  LS LL    S       D+  + P+H+AC+ G      +LLE+ KC 
Sbjct: 714 PLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQ-KCF 772

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETD-RHITDQQGRSPL 393
              + G   +PLH A    H     +LL   ++      D +GR+PL
Sbjct: 773 RKFI-GNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPL 818



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 7/130 (5%)

Query: 291 PLHRSACEGDS---ELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCN 347
           PLH S   G +    LL  +     +V+  D+    P+  A  YG ++A  +LLEK + N
Sbjct: 612 PLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEK-EAN 670

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEA 407
            + ++    + LH     GH E VQ+LL   E      D +GR+PL+         W   
Sbjct: 671 VDTVDILGCTALHRGIMTGHEECVQMLLEQ-EVSILCKDSRGRTPLHYAAARGHATW--L 727

Query: 408 AKLLKEAINK 417
           ++LL+ A+++
Sbjct: 728 SELLQMALSE 737



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 318 DSDHWAPIHYACWYGKVEATRILLEKGKCN-PNLLNGQLSSPLHFAAGGGHAEIVQILLN 376
           D + +  IHYA  YG  +   +LLE+         +G   SPLH AA  GH + +++LL 
Sbjct: 504 DKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLL- 562

Query: 377 HPETDRHITDQQGRSPLNI 395
               D  I D++GR+ L++
Sbjct: 563 QSLVDLDIRDEKGRTALDL 581



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 32/112 (28%), Positives = 49/112 (43%), Gaps = 16/112 (14%)

Query: 290 FPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKG----- 344
           FPLH +A    S+   +LLS  F ++  D      +H A   G VE  ++L   G     
Sbjct: 349 FPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHK 408

Query: 345 --KCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
             KC          +PLH+AA   H   ++ L+     + + TD  GR+ L+
Sbjct: 409 KDKCG--------RTPLHYAAANCHFHCIETLVT-TGANVNETDDWGRTALH 451



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 28/104 (26%), Positives = 53/104 (50%), Gaps = 2/104 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  GD+E++  L+     VN  D+    P+H A      EA ++L+ K   + N 
Sbjct: 19  PLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLI-KHSADVNA 77

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
            +    +PLH AA     +  ++++    +  +++D+ GR+ L+
Sbjct: 78  RDKNWQTPLHVAAANKAVKCAEVII-PLLSSVNVSDRGGRTALH 120



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 5/114 (4%)

Query: 274 SMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGK 333
           S+ S  +DK R      PL  +A     E L  LL     VN +D+     +  A   G+
Sbjct: 805 SIVSCRDDKGRT-----PLRAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQ 859

Query: 334 VEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 387
             A  IL+   + +  + +  L++PLH A   GH +   ++L+  + +  I ++
Sbjct: 860 AGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEK 913



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 19/140 (13%)

Query: 270 KWQRSMSSVTEDKERQWVD---DFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIH 326
           ++ RS + +    E   VD   + PLH +A  G   L++ L +      +       P+H
Sbjct: 293 RFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLH 352

Query: 327 YACWYGKVEATRILLEKGKCNPNLLNGQLSSP-------LHFAAGGGHAEIVQILLNHPE 379
            A      +  R LL  G         ++ +P       LH AA GG+ E ++ LL    
Sbjct: 353 LAALNAHSDCCRKLLSSG--------FEIDTPDKFGRTCLHAAAAGGNVECIK-LLQSSG 403

Query: 380 TDRHITDQQGRSPLNICEEN 399
            D H  D+ GR+PL+    N
Sbjct: 404 ADFHKKDKCGRTPLHYAAAN 423



 Score = 38.1 bits (87), Expect = 0.029
 Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 6/88 (6%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKV----EATRILLEKGKCN 347
           LHR    G  E +  LL +  S+   DS    P+HYA   G      E  ++ L +  C 
Sbjct: 682 LHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDC- 740

Query: 348 PNLLNGQLSSPLHFAAGGGHAEIVQILL 375
               + Q  +PLH+A   G+   +++LL
Sbjct: 741 -CFKDNQGYTPLHWACYNGNENCIEVLL 767



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 3/107 (2%)

Query: 291 PLHRSACEGDSELLSRLLSERFS--VNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
           PLH +         S LL    S  V+  D     P+  A +   VE  ++LL +     
Sbjct: 782 PLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVECLQLLL-RHSAPV 840

Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
           N ++    + L  AA  G A  V IL+N  + D  + D+   +PL++
Sbjct: 841 NAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHL 887



 Score = 33.1 bits (74), Expect = 0.95
 Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWA---PIHYACWYGKVEATRILLEKGKCNP 348
           +H +A  G  + L  LL ER +    +SD  A   P+H A + G  +A  +LL+    + 
Sbjct: 511 IHYAAAYGHRQCLELLL-ERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQS-LVDL 568

Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLN 376
           ++ + +  + L  AA  GH E V+ L+N
Sbjct: 569 DIRDEKGRTALDLAAFKGHTECVEALIN 596



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 30/137 (21%), Positives = 55/137 (40%), Gaps = 28/137 (20%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYG----------------KV 334
           PLH +A       +  L++   +VN+ D      +HYA                    ++
Sbjct: 416 PLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEEL 475

Query: 335 EATRILLEK-----------GKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH 383
           E  R L EK              NP++ + +  + +H+AA  GH + +++LL    +   
Sbjct: 476 ERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFE 535

Query: 384 ITDQQG-RSPLNICEEN 399
            +D    +SPL++   N
Sbjct: 536 ESDSGATKSPLHLAAYN 552


>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
           sapiens]
          Length = 522

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 5/120 (4%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLL 351
           LH +A     + +  LL    +VN L   + + +HYA   G  + +R+L+  G C  N++
Sbjct: 229 LHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGC-ANVV 287

Query: 352 NGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQNNWEEAAKLL 411
           + Q +SPLH A       +V++L+N  ++D +  D + ++PL++  E+    W++ A +L
Sbjct: 288 DHQGASPLHLAVRHNFPALVRLLIN-SDSDVNAVDNRQQTPLHLAAEHA---WQDIADML 343



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 27/95 (28%), Positives = 43/95 (45%), Gaps = 1/95 (1%)

Query: 293 HRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNLLN 352
           HR+A  G  + L  L+      N  D +    +H A   G +   + L++ G  +    N
Sbjct: 164 HRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIG-LDLEEQN 222

Query: 353 GQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQ 387
            +  + LH AAGG H + VQ+LL    T   +T +
Sbjct: 223 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQK 257



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 31/133 (23%), Positives = 58/133 (43%), Gaps = 13/133 (9%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +       L+  L++    VN +D+    P+H A  +   +   +LL  G  + NL
Sbjct: 294 PLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG-VDLNL 352

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDR----HITDQQGRSPLNICEENKQNN--- 403
            + Q  + L  A    H  +V +++      R    H +D  G+S L+  ++++Q     
Sbjct: 353 RDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKS-LSFKQDHRQETQQL 411

Query: 404 ----WEEAAKLLK 412
               W  A++ L+
Sbjct: 412 RSVLWRLASRYLQ 424



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 43/175 (24%), Positives = 74/175 (42%), Gaps = 26/175 (14%)

Query: 292 LHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLE-KGKCNPNL 350
           LH +A + +   +  L+  R +    +      +H+A   G  +A R+LLE +   +   
Sbjct: 19  LHEAARQNNVGRMQELIGRRVNTRARNHVGRVALHWAAGAGHEQAVRLLLEHEAAVDEED 78

Query: 351 LNGQLS--------SPLHFAAGGGHAEIVQILLN-----HPE-----TDRHITDQQGRSP 392
             G L+        + L  +A  GH  I+QIL+N     H E     T  H   Q+G  P
Sbjct: 79  AVGALTEARLCFGMNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVP 138

Query: 393 L--NICEENKQNNWEEAAKLLKEAINKPYEKVRIYRMD-----GSYRSVELKHGN 440
           +   I E+ +    +   KL + A ++  E  ++  +D     G   +V+ K GN
Sbjct: 139 VLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGN 193


>gi|18254476 ankyrin repeat and SOCS box-containing protein 5 [Homo
           sapiens]
          Length = 329

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 1/92 (1%)

Query: 286 WVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGK 345
           W D  PLH +A +G    L  LLS+ ++VN +  DH  P+H AC    V   R LLE G 
Sbjct: 68  WADRSPLHEAASQGRLLALRTLLSQGYNVNAVTLDHVTPLHEACLGDHVACARTLLEAG- 126

Query: 346 CNPNLLNGQLSSPLHFAAGGGHAEIVQILLNH 377
            N N +     +PL  A   G     ++LL +
Sbjct: 127 ANVNAITIDGVTPLFNACSQGSPSCAELLLEY 158



 Score = 33.5 bits (75), Expect = 0.73
 Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 4/86 (4%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           P H +A +G  E L  L+S    V+Q       P++ AC   +      LL  G    ++
Sbjct: 171 PTHEAASKGHHECLDILISWGIDVDQEIPHLGTPLYVACMSQQFHCIWKLLYAG---ADV 227

Query: 351 LNGQL-SSPLHFAAGGGHAEIVQILL 375
             G+   +PLH AA     EIV +LL
Sbjct: 228 QKGKYWDTPLHAAAQQSSTEIVNLLL 253



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 4/72 (5%)

Query: 271 WQRSMSSVTEDKERQWVDDFPLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACW 330
           W+   +     K + W  D PLH +A +  +E+++ LL     +N  +++   PI  A  
Sbjct: 218 WKLLYAGADVQKGKYW--DTPLHAAAQQSSTEIVNLLLEFGADINAKNTELLRPIDVATS 275

Query: 331 YGKVEATRILLE 342
              VE  RILL+
Sbjct: 276 SSMVE--RILLQ 285


>gi|90186267 ankyrin repeat domain 55 isoform 1 [Homo sapiens]
          Length = 614

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 32/109 (29%), Positives = 62/109 (56%), Gaps = 5/109 (4%)

Query: 291 PLHRSACEGDSELLSRLLSER--FSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
           PLH +  E D  LL+ LL +     +N  D++   P+H+A ++ + + T++LL+KG  +P
Sbjct: 130 PLHAATAEPDMRLLTVLLQQSNISEINHQDNEGMTPLHWAAFHNQPQHTQMLLKKG-ADP 188

Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHIT--DQQGRSPLNI 395
            L++    + LH+A   G+  +  I+L+H +    I   D+ G++ ++I
Sbjct: 189 TLVDKDFKTALHWAVQSGNRILCSIILSHHQGPSIINYDDESGKTCVHI 237



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 2/91 (2%)

Query: 292 LHRSACEGDSELLSRLLS-ERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           +H +A  G S+++  L      ++  LD D   P+H+A   GK E  + LLE G  + NL
Sbjct: 235 VHIAAAAGFSDIIHELARVPECNLQALDVDDRTPLHWAAAAGKAECVQSLLELGM-DSNL 293

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETD 381
            +   S+PL +A   GH   V++L     T+
Sbjct: 294 RDINESTPLAYALYCGHTACVKLLSQESRTE 324



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 4/105 (3%)

Query: 292 LHRSACEGDSELLSRLLSERFS---VNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNP 348
           LH +   G+  L S +LS       +N  D      +H A   G  +    L    +CN 
Sbjct: 199 LHWAVQSGNRILCSIILSHHQGPSIINYDDESGKTCVHIAAAAGFSDIIHELARVPECNL 258

Query: 349 NLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPL 393
             L+    +PLH+AA  G AE VQ LL     D ++ D    +PL
Sbjct: 259 QALDVDDRTPLHWAAAAGKAECVQSLL-ELGMDSNLRDINESTPL 302


>gi|30425444 ankyrin repeat and kinase domain containing 1 [Homo
           sapiens]
          Length = 765

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 30/105 (28%), Positives = 58/105 (55%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PL  +A +   +L + LL+     N++D D WAP+H+A   G     R+LL+ G C  + 
Sbjct: 398 PLLIAAQDQQPDLCALLLAHGADANRVDEDGWAPLHFAAQNGDDGTARLLLDHGAC-VDA 456

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
              +  +PLH AA      + ++L++  + D ++ + +G++PL++
Sbjct: 457 QEREGWTPLHLAAQNNFENVARLLVSR-QADPNLHEAEGKTPLHV 500



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 32/105 (30%), Positives = 46/105 (43%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A  G   +   LL    S+       W P+H A + G +E   +L E    N   
Sbjct: 563 PLHTAAARGKYLICKMLLRYGASLELPTHQGWTPLHLAAYKGHLEIIHLLAE-SHANMGA 621

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
           L     +PLH AA  G   +V  LL     D +  +Q G +PL++
Sbjct: 622 LGAVNWTPLHLAARHGEEAVVSALL-QCGADPNAAEQSGWTPLHL 665



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 29/105 (27%), Positives = 49/105 (46%), Gaps = 2/105 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A +G  E++  L     ++  L + +W P+H A  +G+      LL+ G  +PN 
Sbjct: 596 PLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCG-ADPNA 654

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNI 395
                 +PLH A        V  LL H   + H  ++ G +P ++
Sbjct: 655 AEQSGWTPLHLAVQRSTFLSVINLLEH-HANVHARNKVGWTPAHL 698



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 28/84 (33%), Positives = 39/84 (46%), Gaps = 1/84 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +   G    +  LL      + LD   + P+H A   GK    ++LL  G  +  L
Sbjct: 530 PLHLAVERGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYG-ASLEL 588

Query: 351 LNGQLSSPLHFAAGGGHAEIVQIL 374
              Q  +PLH AA  GH EI+ +L
Sbjct: 589 PTHQGWTPLHLAAYKGHLEIIHLL 612



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 2/104 (1%)

Query: 291 PLHRSACEGDSELLSRLLSERFSVNQLDSDHWAPIHYACWYGKVEATRILLEKGKCNPNL 350
           PLH +A      +   L+S +   N  +++   P+H A ++G V   ++L  +G    + 
Sbjct: 464 PLHLAAQNNFENVARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQG-AELDA 522

Query: 351 LNGQLSSPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLN 394
               L +PLH A   G    +Q LL        + DQ G  PL+
Sbjct: 523 QQRNLRTPLHLAVERGKVRAIQHLLKSGAVPDAL-DQSGYGPLH 565



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 21/76 (27%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 324 PIHYACWYGKVEATRILLEKGKCNPNLLNGQLSSPLHFAAGGGHAEIVQILLNHPETDRH 383
           P+H+    G VE  R+LL   + + +       +PL  AA     ++  +LL H   D +
Sbjct: 365 PLHFLVAQGSVEQVRLLLAH-EVDVDCQTASGYTPLLIAAQDQQPDLCALLLAH-GADAN 422

Query: 384 ITDQQGRSPLNICEEN 399
             D+ G +PL+   +N
Sbjct: 423 RVDEDGWAPLHFAAQN 438



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 1/45 (2%)

Query: 357 SPLHFAAGGGHAEIVQILLNHPETDRHITDQQGRSPLNICEENKQ 401
           +PLHF    G  E V++LL H E D       G +PL I  +++Q
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAH-EVDVDCQTASGYTPLLIAAQDQQ 407


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,424,782
Number of Sequences: 37866
Number of extensions: 1214611
Number of successful extensions: 4788
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 119
Number of HSP's that attempted gapping in prelim test: 3063
Number of HSP's gapped (non-prelim): 1164
length of query: 736
length of database: 18,247,518
effective HSP length: 110
effective length of query: 626
effective length of database: 14,082,258
effective search space: 8815493508
effective search space used: 8815493508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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