Search of human proteins with 33667117

Search of human proteins with 33667117

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
         (904 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]                    1811   0.0  
gi|31324577 molecule interacting with Rab13 [Homo sapiens]            419   e-117
gi|170172518 microtubule associated monoxygenase, calponin and L...   147   3e-35
gi|209862789 microtubule associated monoxygenase, calponin and L...   147   3e-35
gi|205360947 microtubule associated monoxygenase, calponin and L...   130   6e-30
gi|226530313 microtubule associated monoxygenase, calponin and L...   130   6e-30
gi|7662284 microtubule associated monoxygenase, calponin and LIM...   120   7e-27
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [...   117   6e-26
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ...   115   2e-25
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ...   115   2e-25
gi|4501893 actinin, alpha 2 [Homo sapiens]                            112   2e-24
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]          111   3e-24
gi|4557241 actinin, alpha 3 [Homo sapiens]                            111   3e-24
gi|209862793 microtubule associated monoxygenase, calponin and L...   110   6e-24
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]                108   2e-23
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]                108   2e-23
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]                  108   2e-23
gi|118918413 MICAL C-terminal like [Homo sapiens]                     106   1e-22
gi|67782321 spectrin beta isoform a [Homo sapiens]                    104   3e-22
gi|67782319 spectrin beta isoform b [Homo sapiens]                    104   3e-22
gi|12025678 actinin, alpha 4 [Homo sapiens]                           103   6e-22
gi|150378549 tangerin [Homo sapiens]                                  103   6e-22
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]     101   3e-21
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]     101   3e-21
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]     101   3e-21
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]     101   3e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni...   100   8e-21
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]         97   9e-20
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    94   6e-19
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof...    94   6e-19

>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
          Length = 904

 Score = 1811 bits (4691), Expect = 0.0
 Identities = 904/904 (100%), Positives = 904/904 (100%)

Query: 1   MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60
           MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE
Sbjct: 1   MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60

Query: 61  NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKR 120
           NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKR
Sbjct: 61  NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKR 120

Query: 121 ASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALA 180
           ASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALA
Sbjct: 121 ASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALA 180

Query: 181 GSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTS 240
           GSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTS
Sbjct: 181 GSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTS 240

Query: 241 HLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASV 300
           HLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASV
Sbjct: 241 HLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASV 300

Query: 301 PAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAAS 360
           PAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAAS
Sbjct: 301 PAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAAS 360

Query: 361 HPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKF 420
           HPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKF
Sbjct: 361 HPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKF 420

Query: 421 FQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAA 480
           FQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAA
Sbjct: 421 FQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPATAA 480

Query: 481 VPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLA 540
           VPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLA
Sbjct: 481 VPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLA 540

Query: 541 ESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPA 600
           ESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPA
Sbjct: 541 ESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPA 600

Query: 601 ERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPS 660
           ERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPS
Sbjct: 601 ERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPS 660

Query: 661 PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALP 720
           PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALP
Sbjct: 661 PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALP 720

Query: 721 GETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVD 780
           GETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVD
Sbjct: 721 GETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVD 780

Query: 781 WFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQEL 840
           WFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQEL
Sbjct: 781 WFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQEL 840

Query: 841 LEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQRKKSKFRLSKIWSPKSKS 900
           LEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQRKKSKFRLSKIWSPKSKS
Sbjct: 841 LEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGLQRKKSKFRLSKIWSPKSKS 900

Query: 901 SPSQ 904
           SPSQ
Sbjct: 901 SPSQ 904


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score =  419 bits (1077), Expect = e-117
 Identities = 332/928 (35%), Positives = 443/928 (47%), Gaps = 130/928 (14%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WCR+QCEGYR V I ++++SFRDGLAFCAILHRHRPDL++F +L K+N++ENN+LA
Sbjct: 7   ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDS 125
           F VAE+ LGIPALLD  DMV++ VPD LSI+TYVSQYYN+F   SP  G AGV       
Sbjct: 67  FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF--CSP--GQAGV------- 115

Query: 126 EEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALAGSLVS 185
                   +P +    P   P+  P  +P +   V Q     +G       +   G   S
Sbjct: 116 --------SPPRKGLAPCSPPSVAP--TPVEPEDVAQGEELSSG----SLSEQGTGQTPS 161

Query: 186 STCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSHLPAA 245
           STC  C +HVHLVQR+LADGRLYHR CFRC++CS TL  GAY+   E GTFVC  H    
Sbjct: 162 STCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH---C 218

Query: 246 ASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNS----------- 294
           A   P         P +           + A++     PS+  PA   +           
Sbjct: 219 ARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARP 278

Query: 295 --PARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAA 352
             P +  VP      A+        +P + SES     PT    RPR +         A 
Sbjct: 279 QIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTP---RPRSSLQQENLVEQAG 335

Query: 353 PCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVD-PPAWTPS-- 409
             +        +P   P   P   +G  APR   P  TL  +         PP+ +P   
Sbjct: 336 SSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPP 395

Query: 410 ASRTQQARNKFFQTSAVP-PGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGA 468
           +  ++Q  N   +  A P P  SL  +   P         +E+  +  ++A +A   A +
Sbjct: 396 SQDSRQVENGGTEEVAQPSPTASLESKPYNP--------FEEEEEDKEEEAPAAPSLATS 447

Query: 469 PAPGRPS-------PATAAVPSSQPKTE------APQASPL---AKPLQSSSPRVLGLPS 512
           PA G P        P     P+S PKT+      AP ASPL   A  L  S P     PS
Sbjct: 448 PALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEP-----PS 502

Query: 513 RMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDM 572
               PA LS  S S  SA   AG   L E   V +  + S P   AP   G   +L+ + 
Sbjct: 503 ATPSPA-LSVESLSSESASQTAG-AELLEPPAVPK--SSSEPAVHAPGTPGNPVSLSTNS 558

Query: 573 STSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSV 632
           S +   G+   P   R    P      A RT     P+  A+P +G  P           
Sbjct: 559 SLA-SSGELVEP---RVEQMPQASPGLAPRTRGSSGPQP-AKPCSGATP----------- 602

Query: 633 HITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQ 692
             T   +  DR+P P SPG S P          +L V +S        +P P    A   
Sbjct: 603 --TPLLLVGDRSPVP-SPGSSSP----------QLQVKSSCKENPFNRKPSPAASPA--- 646

Query: 693 SWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLD 752
                 KK     KP RP +P +   L    V +       Y+  E+I  ++  IERRLD
Sbjct: 647 -----TKKATKGSKPVRPPAPGHGFPLIKRKVQA-----DQYIPEEDIHGEMDTIERRLD 696

Query: 753 ALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQL 812
           ALE RGV LE++LR    +  ED ++VDWF LIHEK LL+R+ESEL+Y  K Q LE++Q 
Sbjct: 697 ALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQA 756

Query: 813 DIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQML 872
           D+E ELR L+ KPE   + ++R RE+ L+++ V+ +  R+ I++ LDEDR RE+EED+ML
Sbjct: 757 DVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKML 816

Query: 873 RDMIEKLGLQR-------KKSKFRLSKI 893
             MI+K   QR       KK KF+  K+
Sbjct: 817 EAMIKKKEFQREAEPEGKKKGKFKTMKM 844


>gi|170172518 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 3 [Homo sapiens]
          Length = 966

 Score =  147 bits (372), Expect = 3e-35
 Identities = 91/294 (30%), Positives = 144/294 (48%), Gaps = 65/294 (22%)

Query: 10  WCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVA 69
           WC++Q +GY  VN+ ++T S++ GLA CAI+HR+RPDLI+F +L ++N+ +NN+LAF +A
Sbjct: 527 WCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIA 586

Query: 70  EEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG--------------------- 108
           E+ LGI  ++  ++M ++  PD+LS++ Y++Q+Y  F                       
Sbjct: 587 EKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIAS 646

Query: 109 -RSPIGGM-----------------------AGVKRASEDSEEEPSGKKAPVQAAKLPSP 144
            RSPI  +                       AG +R +  SEEE + +    +   L S 
Sbjct: 647 TRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVST 706

Query: 145 APARKPPLSPAQTNPV-------VQRRNEGA----------GGPPPKTDQALAGSLVSST 187
              R+  ++    N V       + +  E A          G    +  Q L G   S T
Sbjct: 707 LTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGG---SDT 763

Query: 188 CGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSH 241
           C  C K V++++R  A+G+ +HRSCF+C+ C+ TL   AY    E G F C  H
Sbjct: 764 CYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPH 817


>gi|209862789 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 1 [Homo sapiens]
          Length = 2002

 Score =  147 bits (372), Expect = 3e-35
 Identities = 91/294 (30%), Positives = 144/294 (48%), Gaps = 65/294 (22%)

Query: 10  WCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVA 69
           WC++Q +GY  VN+ ++T S++ GLA CAI+HR+RPDLI+F +L ++N+ +NN+LAF +A
Sbjct: 527 WCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIA 586

Query: 70  EEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG--------------------- 108
           E+ LGI  ++  ++M ++  PD+LS++ Y++Q+Y  F                       
Sbjct: 587 EKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLPSSDTLDLNAEEKAVLIAS 646

Query: 109 -RSPIGGM-----------------------AGVKRASEDSEEEPSGKKAPVQAAKLPSP 144
            RSPI  +                       AG +R +  SEEE + +    +   L S 
Sbjct: 647 TRSPISFLSKLGQTISRKRSPKDKKEKDLDGAGKRRKTSQSEEEEAPRGHRGERPTLVST 706

Query: 145 APARKPPLSPAQTNPV-------VQRRNEGA----------GGPPPKTDQALAGSLVSST 187
              R+  ++    N V       + +  E A          G    +  Q L G   S T
Sbjct: 707 LTDRRMDVAVGNQNKVKYMATQLLAKFEENAPAQSIGIRRQGSMKKEFPQNLGG---SDT 763

Query: 188 CGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSH 241
           C  C K V++++R  A+G+ +HRSCF+C+ C+ TL   AY    E G F C  H
Sbjct: 764 CYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPH 817



 Score =  108 bits (271), Expect = 2e-23
 Identities = 152/578 (26%), Positives = 235/578 (40%), Gaps = 70/578 (12%)

Query: 341  TNSSPMGWSSAAPCTAAAASHPAVPPSAPDP--RPATPQGGGAPRVAAPQTTLSSSSTSA 398
            +N   +G  S     +A  + P+ PP  P P   PAT +     R A P  ++      A
Sbjct: 1435 SNMKTLGSQSFNTSDSAMLTPPSSPPPPPPPGEEPATLRR--KLREAEPNASVVPPPLPA 1492

Query: 399  ATVDPPAWTPSASRTQQARNKFFQTSAVPP--------------GTSLSGR-------GP 437
              + PP   P+    ++ R  F ++    P               +SL  +        P
Sbjct: 1493 TWMRPPR-EPAQPPREEVRKSFVESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPPSCWP 1551

Query: 438  TPSLVLSKDSSKEQARNFLKQALSALEEAGAPAP-GRPSPATAAVPSSQPKTEAPQASPL 496
             P        +KE  R      L ALE    P   G P  +  A   ++ +  A + S  
Sbjct: 1552 RPEKPRHPPLAKENGR------LPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVK 1605

Query: 497  AKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRP-- 554
            ++ L+ +  R L    +ME  +        +AS+ P  G+    +S     +     P  
Sbjct: 1606 SQALRDAMARQLSRMQQMELAS--GAPRPRKASSAPSQGKERRPDSPTRPTLRGSEEPTL 1663

Query: 555  KPEAP---MAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLK-----P 606
            K EA    +    S +   D S +  EG   G +  R++L    RR+  E+  K     P
Sbjct: 1664 KHEATSEEVLSPPSDSGGPDGSFTSSEGSS-GKSKKRSSLFS-PRRNKKEKKSKGEGRPP 1721

Query: 607  KEPRALAEPRAGEAPRKVSGS-FAGSVHITLTPVRPDRTPRPASPGPS--------LPAR 657
            ++P +     A   P+ +  S F+G              P   S G +        LP  
Sbjct: 1722 EKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKSCPSTPSSGATVDSGKHRVLPVV 1781

Query: 658  SPSPPRRRRLAVPASLDVC-DNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANV 716
                  RR+L+     D+  D+ L           +++ EEE    L  K  R +  A  
Sbjct: 1782 RAELQLRRQLSFSEDSDLSSDDVLEKSSQKSRREPRTYTEEE----LNAKLTRRVQKAAR 1837

Query: 717  PALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDS 776
                 E +    RLH   +    IQRQLQ +E R   LE RGV +EK LR   G   +D 
Sbjct: 1838 RQAKQEELK---RLHRAQI----IQRQLQQVEERQRRLEERGVAVEKALRGEAGMGKKDD 1890

Query: 777  --LMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQER 834
              LM +WF L+ EK  ++R ESELM  ++   LE++Q  ++ ELR  MA  + LK+ +E 
Sbjct: 1891 PKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQELRERMAVEDHLKTEEEL 1950

Query: 835  RREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQML 872
              E+++L + +  V  R  +V  L+E RLRE+EED+ L
Sbjct: 1951 SEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDL 1988



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 122/486 (25%), Positives = 173/486 (35%), Gaps = 64/486 (13%)

Query: 293  NSPARASVPAAPNPAATSATSVHVR---SPARPSESRLAPTPTEGKVRPRVTNSSPMGWS 349
            +SP+       P PAAT   S   R    P  P E   A  P++ K       S P+   
Sbjct: 1172 HSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVTLP 1231

Query: 350  SAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPS 409
             A    +  +  P  P +A  P P+       P  + PQ       ++ ATV  P  T S
Sbjct: 1232 EARTPVSPGSPQPQPPVAASTPPPSP-----LPICSQPQ------PSTEATVPSP--TQS 1278

Query: 410  ASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQA----RNFLKQA------ 459
              R Q A  K     A  P  S S         L+ D +  ++      ++K A      
Sbjct: 1279 PIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIRRSL 1338

Query: 460  -LSALEEAGAPAPGRPSPATAAV---PSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRME 515
             L+ ++ +  P P  P+PA   V     S  K+   +   L KPL  S P+ LGLP    
Sbjct: 1339 GLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPL--SIPKRLGLPKPEG 1396

Query: 516  PPAPLSTSSTSQASALPPA--GRRNLAESSGVGRVGAGSRPKPEAPMA--KGKSTTLTQD 571
             P  L T  +     L  A   RR L+ SSG+G  G+ S  K     +     S  LT  
Sbjct: 1397 EPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPP 1456

Query: 572  MSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEP--RAGEAPR-KVSGSF 628
             S        + PA  R  L+  +   P    + P  P     P     + PR +V  SF
Sbjct: 1457 SSPPPPPPPGEEPATLRRKLREAE---PNASVVPPPLPATWMRPPREPAQPPREEVRKSF 1513

Query: 629  AGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQE 688
              SV         + T    +   SL  +  +PP                W RPE P   
Sbjct: 1514 VESVEEIPFADDVEDTYDDKTEDSSLQEKFFTPP--------------SCWPRPEKPRHP 1559

Query: 689  ARVQSWKEEEKKPHLQG-----KPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQ 743
                  KE  + P L+G     K G PL  A    L  E + +  +        + + RQ
Sbjct: 1560 PLA---KENGRLPALEGTLQPQKRGLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQ 1616

Query: 744  LQDIER 749
            L  +++
Sbjct: 1617 LSRMQQ 1622



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 70/331 (21%), Positives = 114/331 (34%), Gaps = 50/331 (15%)

Query: 465  EAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSS 524
            +A +P       A   +P   P TE PQ  P+    Q  SP     P  + P       +
Sbjct: 1153 QATSPIRSPQESALLFIPVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADA 1212

Query: 525  TSQASAL-PPAGRRNLAESSGVGRVGAGSRPKPEAPMAKG--------------KSTTLT 569
             S   A+  P   + +        V  GS P+P+ P+A                 ST  T
Sbjct: 1213 PSDLKAVHSPIRSQPVTLPEARTPVSPGS-PQPQPPVAASTPPPSPLPICSQPQPSTEAT 1271

Query: 570  QDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFA 629
                T      +  PA     L P+  +S ++   +   P A+ E  A      V   + 
Sbjct: 1272 VPSPTQSPIRFQPAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDE--ALRRSDLVEEFWM 1329

Query: 630  GSVHIT----LTPVRPDRTPRPASPGPSLPARS------PSPPRRRRLAVPASLDVCDNW 679
             S  I     LTPV   + P P+ P P+    S         P+   L +   L +    
Sbjct: 1330 KSAEIRRSLGLTPVDRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRL 1389

Query: 680  LRPEPPGQ-----------EARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETV---- 724
              P+P G+           +  ++S +EE ++       G   S +N+  L  ++     
Sbjct: 1390 GLPKPEGEPLSLPTPRSPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSD 1449

Query: 725  -------TSPVRLHPDYLSPEEIQRQLQDIE 748
                   +SP    P    P  ++R+L++ E
Sbjct: 1450 SAMLTPPSSPPPPPPPGEEPATLRRKLREAE 1480


>gi|205360947 microtubule associated monoxygenase, calponin and LIM
           domain containing 1 isoform 1 [Homo sapiens]
          Length = 1067

 Score =  130 bits (327), Expect = 6e-30
 Identities = 94/345 (27%), Positives = 153/345 (44%), Gaps = 55/345 (15%)

Query: 7   LQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAF 66
           L +WC++Q  GY  V++ ++++S+ DGLA CA+++R +P L+  S L+     E    A 
Sbjct: 514 LLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWAL 573

Query: 67  RVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF----HGRSPI-----GGMAG 117
           +VAE  LGI  ++ A+ +VA   P  L ++ Y+S +++ F    H   P+     G  + 
Sbjct: 574 KVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSA 631

Query: 118 V-----------KRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNE 166
           V           +  ++++ E+  GKK  ++   + +  P+ + P  P    P+      
Sbjct: 632 VLFLSKLQRTLQRSRAKENAEDAGGKKLRLE---MEAETPSTEVPPDPEPGVPLT----- 683

Query: 167 GAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGA 226
               PP +  +A AG L    C +CG+H+++++R   +G  +HRSCFRC  C  TL  G 
Sbjct: 684 ----PPSQHQEAGAGDL----CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGG 735

Query: 227 YKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSA 286
           Y+     G F C  HLP                  A G D             N   P  
Sbjct: 736 YEQHPGDGHFYCLQHLPQT-------------DHKAEGSDRGPESPELPTPSENSMPPGL 782

Query: 287 WEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTP 331
             P A    A       P+P+  +   + + SP R   S L  TP
Sbjct: 783 STPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 823



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 2/134 (1%)

Query: 734  YLSPEEIQRQLQDIERRLDALELRGVELEKRLRA-AEGDDAEDSLMV-DWFWLIHEKQLL 791
            +   + IQR+L +IE  L  LE  GV+LE  LR  +   + +  L V     L+ +K  L
Sbjct: 925  FCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSL 984

Query: 792  LRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDR 851
            + +E+ELM   +   LEE+Q  ++ ELR  M + E LK+  +R+ E ++L + V  VN R
Sbjct: 985  VAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQR 1044

Query: 852  SDIVDSLDEDRLRE 865
              ++   +E RL E
Sbjct: 1045 DALIRFQEERRLSE 1058


>gi|226530313 microtubule associated monoxygenase, calponin and LIM
           domain containing 1 isoform 2 [Homo sapiens]
          Length = 981

 Score =  130 bits (327), Expect = 6e-30
 Identities = 94/345 (27%), Positives = 153/345 (44%), Gaps = 55/345 (15%)

Query: 7   LQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAF 66
           L +WC++Q  GY  V++ ++++S+ DGLA CA+++R +P L+  S L+     E    A 
Sbjct: 428 LLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWAL 487

Query: 67  RVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF----HGRSPI-----GGMAG 117
           +VAE  LGI  ++ A+ +VA   P  L ++ Y+S +++ F    H   P+     G  + 
Sbjct: 488 KVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQASPGTSSA 545

Query: 118 V-----------KRASEDSEEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNE 166
           V           +  ++++ E+  GKK  ++   + +  P+ + P  P    P+      
Sbjct: 546 VLFLSKLQRTLQRSRAKENAEDAGGKKLRLE---MEAETPSTEVPPDPEPGVPLT----- 597

Query: 167 GAGGPPPKTDQALAGSLVSSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGA 226
               PP +  +A AG L    C +CG+H+++++R   +G  +HRSCFRC  C  TL  G 
Sbjct: 598 ----PPSQHQEAGAGDL----CALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGG 649

Query: 227 YKATGEPGTFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSA 286
           Y+     G F C  HLP                  A G D             N   P  
Sbjct: 650 YEQHPGDGHFYCLQHLPQT-------------DHKAEGSDRGPESPELPTPSENSMPPGL 696

Query: 287 WEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTP 331
             P A    A       P+P+  +   + + SP R   S L  TP
Sbjct: 697 STPTASQEGA----GPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 737



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 46/134 (34%), Positives = 73/134 (54%), Gaps = 2/134 (1%)

Query: 734 YLSPEEIQRQLQDIERRLDALELRGVELEKRLRA-AEGDDAEDSLMV-DWFWLIHEKQLL 791
           +   + IQR+L +IE  L  LE  GV+LE  LR  +   + +  L V     L+ +K  L
Sbjct: 839 FCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQKKLWVGQLLQLVDKKNSL 898

Query: 792 LRQESELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDR 851
           + +E+ELM   +   LEE+Q  ++ ELR  M + E LK+  +R+ E ++L + V  VN R
Sbjct: 899 VAEEAELMITVQELNLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQR 958

Query: 852 SDIVDSLDEDRLRE 865
             ++   +E RL E
Sbjct: 959 DALIRFQEERRLSE 972


>gi|7662284 microtubule associated monoxygenase, calponin and LIM
           domain containing 2 [Homo sapiens]
          Length = 1124

 Score =  120 bits (300), Expect = 7e-27
 Identities = 67/170 (39%), Positives = 102/170 (60%), Gaps = 18/170 (10%)

Query: 7   LQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAF 66
           L  WC+QQ EGY+ VN+ ++TTS+R GLA CAI+HR RP+LINF +L +++  ENN+LAF
Sbjct: 522 LLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAF 581

Query: 67  RVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDSE 126
            VAE   GIP +   ++M + + PD+LS++ Y+S++Y  F G +P+  +        DS 
Sbjct: 582 DVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRG-TPLRPV--------DSW 632

Query: 127 EEPSGKKAPVQAAK-------LPSPAPARKPPLSPAQT--NPVVQRRNEG 167
            +  G+ A +  AK       L    P ++ P    QT  N + +RR +G
Sbjct: 633 RKNYGENADLSLAKSSISNNYLNLTFPRKRTPRVDGQTGENDMNKRRRKG 682



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 24/57 (42%), Positives = 32/57 (56%)

Query: 185  SSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSH 241
            S TC  C K V++++R  A+G  +HR CFRC  C+ TL   AY    + G F C  H
Sbjct: 999  SDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCDEGKFYCKPH 1055


>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
           [Homo sapiens]
          Length = 2564

 Score =  117 bits (292), Expect = 6e-26
 Identities = 57/101 (56%), Positives = 73/101 (72%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY +VNI N TTS+RDGLAF A++HRHRPDL++FS L K N   N + A
Sbjct: 185 ALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQRA 244

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           FR AE+HLG+  LLD ED V ++ PD  SI+TYV  +Y+YF
Sbjct: 245 FRTAEQHLGLARLLDPED-VNMEAPDEKSIITYVVSFYHYF 284



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 57/219 (26%), Positives = 75/219 (34%), Gaps = 42/219 (19%)

Query: 471  PGRPSPATA-AVPSSQPKTEA-PQASPLAKPL---QSSSPRVLGLPSRMEPPAPLSTSST 525
            PGR  PA   A P    +T A P A+   +P    Q S+ R   LP R  P    S   +
Sbjct: 2199 PGRVEPAALPAAPEDAAETPATPAAAEQVRPRPERQESADRAEELPRRRRPERQESVDQS 2258

Query: 526  SQASALPPAGRRNLAESSGVGRVGAGSRPKPE-----------------------APMAK 562
             +A+      R+  AE      +  G   + E                         + K
Sbjct: 2259 EEAARRRRPERQESAEHEAAHSLTLGRYEQMERRRERRERRLERQESSEQEMPIRGDLVK 2318

Query: 563  GKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPA----------ERTLKPKEPRAL 612
            GK+T    D+   LQE +E GP        P  R  P           ERT +P  PRA 
Sbjct: 2319 GKATLA--DIVEQLQE-KEAGPGLPAGPSLPQPRELPPGRLPNGLELPERTPRPDRPRAR 2375

Query: 613  AEPRAGEAPR-KVSGSFAGSVHITLTPVRPDRTPRPASP 650
              P+    PR +  G   GS      P +    P P  P
Sbjct: 2376 DRPKPRRRPRPREGGEGGGSRRSRSAPAQGGSAPAPPPP 2414


>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
           sapiens]
          Length = 2155

 Score =  115 bits (287), Expect = 2e-25
 Identities = 55/101 (54%), Positives = 74/101 (73%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY +VNI N TTS+RDG+AF A++H+HRPDLI+F  LKK N + N + A
Sbjct: 165 ALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNA 224

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           F +AE+HLG+  LLD ED +++  PD  SI+TYV  YY+YF
Sbjct: 225 FNLAEQHLGLTKLLDPED-ISVDHPDEKSIITYVVTYYHYF 264


>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
           sapiens]
          Length = 2364

 Score =  115 bits (287), Expect = 2e-25
 Identities = 55/101 (54%), Positives = 74/101 (73%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY +VNI N TTS+RDG+AF A++H+HRPDLI+F  LKK N + N + A
Sbjct: 178 ALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNA 237

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           F +AE+HLG+  LLD ED +++  PD  SI+TYV  YY+YF
Sbjct: 238 FNLAEQHLGLTKLLDPED-ISVDHPDEKSIITYVVTYYHYF 277


>gi|4501893 actinin, alpha 2 [Homo sapiens]
          Length = 894

 Score =  112 bits (279), Expect = 2e-24
 Identities = 53/107 (49%), Positives = 74/107 (69%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   YR+VNI N  TS++DGL  CA++HRHRPDLI++S L K++   N
Sbjct: 152 SAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGN 211

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
             LA  +AE+HL IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 212 INLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAG 258


>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
          Length = 2390

 Score =  111 bits (278), Expect = 3e-24
 Identities = 55/101 (54%), Positives = 74/101 (73%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY +VN+ N TTS+RDGLAF AI+H+HRPDL++F +LKK N + N + A
Sbjct: 181 ALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNA 240

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           F +AE+ LG+  LLD ED V +  PD  SI+TYV+ YY+YF
Sbjct: 241 FNLAEKELGLTKLLDPED-VNVDQPDEKSIITYVATYYHYF 280


>gi|4557241 actinin, alpha 3 [Homo sapiens]
          Length = 901

 Score =  111 bits (277), Expect = 3e-24
 Identities = 52/107 (48%), Positives = 76/107 (71%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   YR+VN+ N  TS++DGLA CA++HRHRPDLI+++ L+K++   N
Sbjct: 159 SAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGN 218

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
              AF VAE++L IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 219 LNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAG 265


>gi|209862793 microtubule associated monoxygenase, calponin and LIM
           domain containing 3 isoform 2 [Homo sapiens]
          Length = 1073

 Score =  110 bits (275), Expect = 6e-24
 Identities = 45/102 (44%), Positives = 76/102 (74%)

Query: 10  WCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLAFRVA 69
           WC++Q +GY  VN+ ++T S++ GLA CAI+HR+RPDLI+F +L ++N+ +NN+LAF +A
Sbjct: 527 WCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAFDIA 586

Query: 70  EEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSP 111
           E+ LGI  ++  ++M ++  PD+LS++ Y++Q+Y  F    P
Sbjct: 587 EKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMFKDSLP 628



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 25/57 (43%), Positives = 35/57 (61%)

Query: 185 SSTCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSH 241
           S TC  C K V++++R  A+G+ +HRSCF+C+ C+ TL   AY    E G F C  H
Sbjct: 885 SDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPH 941


>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
          Length = 887

 Score =  108 bits (270), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 74/107 (69%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   Y++VNI N   S++DGL FCA++HRHRP+LI++  L+K++   N
Sbjct: 145 SAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTN 204

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
              AF VAE++L IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 205 LNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSG 251


>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
          Length = 914

 Score =  108 bits (270), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 74/107 (69%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   Y++VNI N   S++DGL FCA++HRHRP+LI++  L+K++   N
Sbjct: 145 SAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTN 204

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
              AF VAE++L IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 205 LNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSG 251


>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
          Length = 892

 Score =  108 bits (270), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 74/107 (69%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   Y++VNI N   S++DGL FCA++HRHRP+LI++  L+K++   N
Sbjct: 145 SAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTN 204

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
              AF VAE++L IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 205 LNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSG 251


>gi|118918413 MICAL C-terminal like [Homo sapiens]
          Length = 695

 Score =  106 bits (264), Expect = 1e-22
 Identities = 58/151 (38%), Positives = 88/151 (58%), Gaps = 2/151 (1%)

Query: 738 EEIQRQLQDIERRLDALELRGVELEKRLR--AAEGDDAEDSLMVDWFWLIHEKQLLLRQE 795
           + IQRQL+++E R  A E++GV LEK LR  A  G   E  L+ +WF L+ EK  L+R E
Sbjct: 545 QAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYE 604

Query: 796 SELMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIV 855
           SEL+  ++   LE+ Q  +E +LR  M K E+ K  ++   EQE+  + +  +  R  +V
Sbjct: 605 SELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNEEQEVFTELMQVIEQRDKLV 664

Query: 856 DSLDEDRLREQEEDQMLRDMIEKLGLQRKKS 886
           DSL+E R+RE+ EDQ     +   G Q  ++
Sbjct: 665 DSLEEQRIREKAEDQHFESFVFSRGCQLSRT 695



 Score = 30.4 bits (67), Expect = 7.8
 Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 6/44 (13%)

Query: 365 PPSAPDPRPATPQGGGAP------RVAAPQTTLSSSSTSAATVD 402
           PP  P P P  P  GGA       R    + + S+SSTS+++ D
Sbjct: 459 PPPPPPPPPPPPTAGGADSKNFPLRAQVTEASSSASSTSSSSAD 502


>gi|67782321 spectrin beta isoform a [Homo sapiens]
          Length = 2328

 Score =  104 bits (260), Expect = 3e-22
 Identities = 53/101 (52%), Positives = 68/101 (67%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY  VN+ N T+S++DGLAF A++H+HRPDLI+F  LK  N   N + A
Sbjct: 178 ALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHA 237

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           F VAE  LGI  LLD ED V  + PD  SI+TYV  +Y+YF
Sbjct: 238 FNVAERQLGIIPLLDPED-VFTENPDEKSIITYVVAFYHYF 277


>gi|67782319 spectrin beta isoform b [Homo sapiens]
          Length = 2137

 Score =  104 bits (260), Expect = 3e-22
 Identities = 53/101 (52%), Positives = 68/101 (67%), Gaps = 1/101 (0%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+ +  GY  VN+ N T+S++DGLAF A++H+HRPDLI+F  LK  N   N + A
Sbjct: 178 ALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLEHA 237

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYF 106
           F VAE  LGI  LLD ED V  + PD  SI+TYV  +Y+YF
Sbjct: 238 FNVAERQLGIIPLLDPED-VFTENPDEKSIITYVVAFYHYF 277


>gi|12025678 actinin, alpha 4 [Homo sapiens]
          Length = 911

 Score =  103 bits (258), Expect = 6e-22
 Identities = 49/107 (45%), Positives = 73/107 (68%)

Query: 2   AAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYEN 61
           +A   L  WC+++   Y++VN+ N   S++DGLAF A++HRHRP+LI +  L+K++   N
Sbjct: 164 SAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTN 223

Query: 62  NKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHG 108
              AF VAE++L IP +LDAED+V    PD  +I+TYVS +Y+ F G
Sbjct: 224 LNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSG 270


>gi|150378549 tangerin [Homo sapiens]
          Length = 1523

 Score =  103 bits (258), Expect = 6e-22
 Identities = 69/192 (35%), Positives = 97/192 (50%), Gaps = 19/192 (9%)

Query: 1    MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60
            +++ ++L +WC++   GYR V I N TTS+R+GLAFCAILHR  PD I++++L   NI +
Sbjct: 1037 VSSSQSLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQ 1096

Query: 61   NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRS------PIGG 114
            NNK AF      LG+  LL+  DMV L VPD+L ++TY+ Q   +  G+         GG
Sbjct: 1097 NNKQAFD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQIRAFCTGQELQLVQLEGGG 1155

Query: 115  MAGVKRASEDSEEEPSGKKAPVQAAKL----------PSPAPARKPPLSP--AQTNPVVQ 162
             AG  R        P    A   A +L          P  A  R    +P  A  N V  
Sbjct: 1156 GAGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAG 1215

Query: 163  RRNEGAGGPPPK 174
            R ++  G   P+
Sbjct: 1216 RASKDGGAEAPR 1227



 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 98/371 (26%), Positives = 155/371 (41%), Gaps = 32/371 (8%)

Query: 543  SGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAER 602
            +G  RVG+     P+   A G +  L    +   QE +E       A      R + A R
Sbjct: 1157 AGTYRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAGR 1216

Query: 603  TLKPKEPRALAEPRAGEAPRK--VSGSFA---GSVHITLTPVR--PDRTPRPASPGPSLP 655
              K     A  E R  E P +  V+G+ A   G V +    V   P   P P + G    
Sbjct: 1217 ASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGGGVRLRRPSVNGEPGSVPPPRAHGSFSH 1276

Query: 656  ARSPS--PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKP--------HLQG 705
             R       RR RL   +S  + D    P+     A     +  +  P          Q 
Sbjct: 1277 VRDADLLKKRRSRLRNSSSFSMDD----PDAGAMGAAAAEGQAPDPSPAPGPPTAADSQQ 1332

Query: 706  KPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLDALELRGVELEKRL 765
             PG        P  PGE       L     + + +  +LQ +E+    ++ R  E+E +L
Sbjct: 1333 PPGGSSPSEEPPPSPGEEAG----LQRFQDTSQYVCAELQALEQEQRQIDGRAAEVEMQL 1388

Query: 766  RAAEGDDA----EDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQLDIEGELRRL 821
            R+     A    E+ L+ +WF L+++K  L+R++ +L    + Q LE +   +  ELR +
Sbjct: 1389 RSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSRELRAM 1448

Query: 822  MAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQMLRDMIEKLGL 881
            +A  +  K+  ++ REQ LLE+ VS VN R ++V  LD       EED+ L   +E+   
Sbjct: 1449 LAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGLEQ--- 1505

Query: 882  QRKKSKFRLSK 892
            +R+K   +LS+
Sbjct: 1506 RRRKLSRQLSR 1516



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 45/181 (24%), Positives = 68/181 (37%), Gaps = 25/181 (13%)

Query: 452 ARNFLKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLP 511
           AR    Q      EAG    G+  P     P + P+  + +  P      + +PR+    
Sbjct: 256 ARTSRGQGSERANEAG----GQVGPEAPRPPETSPEMRSSR-QPAQDTAPTPAPRLRKGS 310

Query: 512 SRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQD 571
             + PP P       +AS  PPAG  +  E+        G+    EA  A+         
Sbjct: 311 DALRPPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGT----EAHGAR--------- 357

Query: 572 MSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAG--EAPRKVSGSFA 629
           +  S+++     P G R  LK  +     +   +P+      EPR+G  EA  K SG  A
Sbjct: 358 LGPSIEDKGSGDPFG-RQRLKAEE----MDTEDRPEASGVDTEPRSGGREANTKRSGVRA 412

Query: 630 G 630
           G
Sbjct: 413 G 413



 Score = 33.5 bits (75), Expect = 0.92
 Identities = 84/346 (24%), Positives = 112/346 (32%), Gaps = 50/346 (14%)

Query: 244 AAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGN----SPARAS 299
           A    +P+    VP+   +   + +T C   + +E  + RP     +  N    SPA  S
Sbjct: 196 AHGPGAPEARARVPQPDPSR--ELKTLC---EEEEEGQGRPQQAVASPSNAEDTSPAPVS 250

Query: 300 VPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAA 359
            PA P  A TS          + SE         G   PR   +SP   SS  P      
Sbjct: 251 APAPP--ARTSR--------GQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQ---- 296

Query: 360 SHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNK 419
                  +AP P P   +G  A R   PQ          A+  PPA   SA  T      
Sbjct: 297 ------DTAPTPAPRLRKGSDALRPPVPQ---GEDEVPKASGAPPAGLGSARET------ 341

Query: 420 FFQTSAVP-PGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAPGRPSPAT 478
             Q  A P  GT   G    PS+       K     F +Q L A EE         S   
Sbjct: 342 --QAQACPQEGTEAHGARLGPSI-----EDKGSGDPFGRQRLKA-EEMDTEDRPEASGVD 393

Query: 479 AAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRN 538
               S   +    ++   A   + SS        +      + T        +P A  R 
Sbjct: 394 TEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMPEARCRG 453

Query: 539 LAESSGVGRVG-AGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDG 583
             E+   G  G  G R + EAP   G S    +    S Q G  +G
Sbjct: 454 TPEAPPRGSQGRLGVRTRDEAP--SGLSLPPAEPAGHSGQLGDLEG 497



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 79/343 (23%), Positives = 109/343 (31%), Gaps = 103/343 (30%)

Query: 366 PSAPDPRPATPQ----------------GGGAP--RVAAPQTTLSSSSTSAATVDPPAWT 407
           P AP+ R   PQ                G G P   VA+P     +S    +   PPA T
Sbjct: 199 PGAPEARARVPQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPART 258

Query: 408 ---PSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALE 464
                + R  +A  +    +  PP TS   R           SS++ A+          +
Sbjct: 259 SRGQGSERANEAGGQVGPEAPRPPETSPEMR-----------SSRQPAQ----------D 297

Query: 465 EAGAPAPG-RPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTS 523
            A  PAP  R        P  Q + E P+AS                     PPA L ++
Sbjct: 298 TAPTPAPRLRKGSDALRPPVPQGEDEVPKASG-------------------APPAGLGSA 338

Query: 524 STSQASALPPAGR-------------RNLAESSGVGRVGAGSRPKPEAPMAKGKST---- 566
             +QA A P  G              +   +  G  R+ A      + P A G  T    
Sbjct: 339 RETQAQACPQEGTEAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRS 398

Query: 567 ----TLTQDMSTSLQEGQEDG-----PAGWRANLKPVDRRSPAERTLKPKEPRALAEPRA 617
                 T+       E +E        A  R+ ++ VD + P    + P E R    P  
Sbjct: 399 GGREANTKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMP-EARCRGTP-- 455

Query: 618 GEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPS 660
            EAP + S    G            RT   A  G SLP   P+
Sbjct: 456 -EAPPRGSQGRLGV-----------RTRDEAPSGLSLPPAEPA 486


>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score =  101 bits (252), Expect = 3e-21
 Identities = 49/107 (45%), Positives = 73/107 (68%), Gaps = 1/107 (0%)

Query: 3   AIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENN 62
           A ++L  WC++  + YR V I N TTS+R+GL+FCAILH  RPDLI++ +L  ++I ENN
Sbjct: 410 ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENN 469

Query: 63  KLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGR 109
           K A+      +GI  LL+  DMV L +PD+L+++TY+ Q   +F G+
Sbjct: 470 KKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQ 515



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 43/140 (30%), Positives = 77/140 (55%), Gaps = 4/140 (2%)

Query: 743  QLQDIERRLDALELRGVELEKRLR----AAEGDDAEDSLMVDWFWLIHEKQLLLRQESEL 798
            +L  +E     ++ R   +EKRLR         + E+++M +WF L+++K  L+R+ ++L
Sbjct: 1006 ELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1065

Query: 799  MYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSL 858
                K   LE +   +  ELR ++A  +  K+  ++RREQ LL++ V+ VN R  +V  L
Sbjct: 1066 SLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL 1125

Query: 859  DEDRLREQEEDQMLRDMIEK 878
            D    + +EED+ L   +E+
Sbjct: 1126 DAQEKQAEEEDEHLERTLEQ 1145


>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
          Length = 1160

 Score =  101 bits (252), Expect = 3e-21
 Identities = 49/107 (45%), Positives = 73/107 (68%), Gaps = 1/107 (0%)

Query: 3   AIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENN 62
           A ++L  WC++  + YR V I N TTS+R+GL+FCAILH  RPDLI++ +L  ++I ENN
Sbjct: 410 ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENN 469

Query: 63  KLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGR 109
           K A+      +GI  LL+  DMV L +PD+L+++TY+ Q   +F G+
Sbjct: 470 KKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQ 515



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 43/140 (30%), Positives = 77/140 (55%), Gaps = 4/140 (2%)

Query: 743  QLQDIERRLDALELRGVELEKRLR----AAEGDDAEDSLMVDWFWLIHEKQLLLRQESEL 798
            +L  +E     ++ R   +EKRLR         + E+++M +WF L+++K  L+R+ ++L
Sbjct: 1006 ELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1065

Query: 799  MYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSL 858
                K   LE +   +  ELR ++A  +  K+  ++RREQ LL++ V+ VN R  +V  L
Sbjct: 1066 SLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL 1125

Query: 859  DEDRLREQEEDQMLRDMIEK 878
            D    + +EED+ L   +E+
Sbjct: 1126 DAQEKQAEEEDEHLERTLEQ 1145


>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
          Length = 1196

 Score =  101 bits (252), Expect = 3e-21
 Identities = 49/107 (45%), Positives = 73/107 (68%), Gaps = 1/107 (0%)

Query: 3   AIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENN 62
           A ++L  WC++  + YR V I N TTS+R+GL+FCAILH  RPDLI++ +L  ++I ENN
Sbjct: 410 ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENN 469

Query: 63  KLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGR 109
           K A+      +GI  LL+  DMV L +PD+L+++TY+ Q   +F G+
Sbjct: 470 KKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQ 515



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 43/140 (30%), Positives = 77/140 (55%), Gaps = 4/140 (2%)

Query: 743  QLQDIERRLDALELRGVELEKRLR----AAEGDDAEDSLMVDWFWLIHEKQLLLRQESEL 798
            +L  +E     ++ R   +EKRLR         + E+++M +WF L+++K  L+R+ ++L
Sbjct: 1042 ELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1101

Query: 799  MYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSL 858
                K   LE +   +  ELR ++A  +  K+  ++RREQ LL++ V+ VN R  +V  L
Sbjct: 1102 SLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL 1161

Query: 859  DEDRLREQEEDQMLRDMIEK 878
            D    + +EED+ L   +E+
Sbjct: 1162 DAQEKQAEEEDEHLERTLEQ 1181


>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
          Length = 1231

 Score =  101 bits (252), Expect = 3e-21
 Identities = 49/107 (45%), Positives = 73/107 (68%), Gaps = 1/107 (0%)

Query: 3   AIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENN 62
           A ++L  WC++  + YR V I N TTS+R+GL+FCAILH  RPDLI++ +L  ++I ENN
Sbjct: 445 ASQSLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENN 504

Query: 63  KLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGR 109
           K A+      +GI  LL+  DMV L +PD+L+++TY+ Q   +F G+
Sbjct: 505 KKAYD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHFSGQ 550



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 43/140 (30%), Positives = 77/140 (55%), Gaps = 4/140 (2%)

Query: 743  QLQDIERRLDALELRGVELEKRLR----AAEGDDAEDSLMVDWFWLIHEKQLLLRQESEL 798
            +L  +E     ++ R   +EKRLR         + E+++M +WF L+++K  L+R+ ++L
Sbjct: 1077 ELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQL 1136

Query: 799  MYKSKAQRLEEQQLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSL 858
                K   LE +   +  ELR ++A  +  K+  ++RREQ LL++ V+ VN R  +V  L
Sbjct: 1137 SLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDL 1196

Query: 859  DEDRLREQEEDQMLRDMIEK 878
            D    + +EED+ L   +E+
Sbjct: 1197 DAQEKQAEEEDEHLERTLEQ 1216


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  100 bits (248), Expect = 8e-21
 Identities = 135/538 (25%), Positives = 195/538 (36%), Gaps = 79/538 (14%)

Query: 239  TSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPA--AGNSPA 296
            TS  P  A A+P   G +P  P   G  +  + +P   +         W P   A   P+
Sbjct: 914  TSSSPKKARATPAPKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 297  RASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTA 356
                PA P+P    A +    +P  P      P+P      P VT  SP G  +A P   
Sbjct: 973  PKGGPATPSPKG--APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 357  AAASHPAVPPSAPDPRP-ATPQGGGAPRVAAPQTTLSSSSTSAATVD------PPAWTPS 409
             A++ PA  P +P   P ATP   GAP    P  TL S     AT        PPA TP 
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAP--TTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088

Query: 410  ASR----TQQARNKFFQTSAVPP----GTSLSGRGPTPSLVLSKDSSKEQARNFLKQALS 461
            + +    T   +      +A PP    G +       P+   +   S        K  L+
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP-------KGGLA 1141

Query: 462  ALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKP------LQSSSPRVLGLPSRME 515
                 GAP     +P +     + P  +    +P A P      L + SP+         
Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 516  PPAP---LSTSSTSQA----SALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTL 568
            PP+P   L+T S   A    +A PP+ +  LA  S     GA + P    P  KG     
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAATPPSPKG----- 1253

Query: 569  TQDMSTSLQEGQEDGPAGWRANLK-----PVDRRSPAERTLKPKEPR---ALAEPRAGEA 620
                +T   +G    PA    +LK     P  + +P    + P  P+   A + P+    
Sbjct: 1254 --GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 621  PRKVS-----GSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDV 675
            P   +     GS  G+      P  P  TP      P+LPA +PS   +     P+S + 
Sbjct: 1312 PPAATPPSPKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS--SKGGPTTPSSKE- 1367

Query: 676  CDNWLRPEPPG-----QEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPV 728
                  P PP      +     +    ++ P +    G P SPA +P  P +   +PV
Sbjct: 1368 -----GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPV 1420



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 125/526 (23%), Positives = 182/526 (34%), Gaps = 49/526 (9%)

Query: 235  TFVCTSHLPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNS 294
            +F+  + L    S     T   P  P   G  + ++ +P   +           P+  N 
Sbjct: 834  SFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNL 893

Query: 295  PARASVPAAPNPAATSATSVHVRSPAR------PSESRLAPTPTEGKVRPRVTNSSPMGW 348
            P     PA P P    A S+   SP +      P     +P+P      P  T  SP G 
Sbjct: 894  PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG- 952

Query: 349  SSAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPR--VAAPQTTLSSSSTSA--ATVDPP 404
              A P    A + PA  P +P   PATP   GAP    A P +     +T +      PP
Sbjct: 953  GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012

Query: 405  AWTPSASRTQQARNKFFQTSAVPP-GTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSAL 463
            A TP + +   A   F + ++ PP  T  S +G   +  L K +    A      A    
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPA------ATLPS 1066

Query: 464  EEAGAPAP---GRPSPATAAVPSSQ--PKTEAPQASPLAKPLQSSSPR--VLGLPSRMEP 516
             + G   P   G P+P  A  PS +  P T +P+ +P+       SP+  +   P +  P
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 517  PAPLST--------------SSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAK 562
              P +T               + +  +A PP+ +  LA        GA + P    P  K
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP---PKGAPTTPAATPPSPK 1183

Query: 563  GKSTTLTQDMSTSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPR-ALAEPRAGEAP 621
            G   T +   + +        P G  A   P  + +P      P  P+  LA P    AP
Sbjct: 1184 GGLATPSPKGAPTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 622  RKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLR 681
               + +         TP        PA+  PSL     +PP +     P    V     +
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK---GAPNPAVVTPPSPK 1298

Query: 682  PEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSP 727
              P     +          P  +G PG P  P   P  P  T  SP
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTP-PPKGAPTPPAVTPPSP 1343



 Score = 90.5 bits (223), Expect = 6e-18
 Identities = 135/540 (25%), Positives = 186/540 (34%), Gaps = 86/540 (15%)

Query: 243  PAAASASPKLT-GLVPRQPGAMGVDSRTSCSPQKAQEANK------ARPSAWEPAAGNSP 295
            PA    SPK +    P   GA    + T  SP+ +  A          P+A  P+    P
Sbjct: 1012 PAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGP 1071

Query: 296  ARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCT 355
            A  S+  AP P A         +P  P      P+P    + P  T  SP G   A P  
Sbjct: 1072 ATPSLKGAPTPPAA--------TPPSPKGGPATPSPKGAPMPPAATPPSPKG-GLATPPH 1122

Query: 356  AAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQ 415
              A + PA  P +P    ATP   GAP    P  T  S     AT  PP   P+      
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAP--TTPAATPPSPKGGLAT-PPPKGAPTTPAATP 1179

Query: 416  ARNKFFQTSAVPPG--TSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAPAP-G 472
               K    +  P G  T+ +   P+P   L+  S K           S       P+P G
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239

Query: 473  RPSPATAAVPSSQ--PKTEAPQASP-------------LAKPLQSSSPRVLGLPSRMEPP 517
             P+   A  PS +  P T  P+ +P             LA P    +P     P+ + PP
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN----PAVVTPP 1295

Query: 518  APLSTSSTSQASALP---------PAGRRNLAESSGVGRVGAGSRPKPE--------APM 560
            +P    +TS     P         P G        G     A + P P+         P 
Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 561  AKGKSTTLTQ---DMSTSLQEGQEDGPA--------GWRANLKPVDRRSPAERTLKPKEP 609
            +KG  TT +        +     + GPA        G        D  SPA   L PK+ 
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 610  RALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASP--GPSLPARSPSPPRRRRL 667
             A    R G A    + S        +TPV   + P  ++P  GP+ P+ S   P    +
Sbjct: 1416 PATPVTREGAA----TPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS-SKGDPTLPAV 1470

Query: 668  AVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSP 727
              P+          P+ P    +V +    +K P      G P  PA +P+ P E   +P
Sbjct: 1471 TPPS----------PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 133/513 (25%), Positives = 188/513 (36%), Gaps = 68/513 (13%)

Query: 243  PAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASVPA 302
            PA    SPK    +P   G     +    SP+KA      R  A  P+ G+    A  P 
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441

Query: 303  APNPAATSATSVHVRSPARPSESR-------LAPTPTEGKVRPRVTNSSPMGWSSAAPCT 355
            +   A   ATS     PA PS            P+P E     +V  SS    + A P  
Sbjct: 1442 SLKKAP--ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 356  AAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAA-----TVDPPAWTPSA 410
              A + PAV PS+P   PATP     P   AP  TL S  T A       + PPA T  +
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDP--IAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557

Query: 411  SRTQQARNKFFQTSAVPPGTSLSG-RGPTPSLVLSKDSSKEQARNFLKQALSALEEAGAP 469
             +   A     +  A P     S     TPS      S KE     +  A+++     AP
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKEL---LIPPAVTSPSPKEAP 1614

Query: 470  APGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLST-----SS 524
             P   +P +   P   P T AP+ +P + P+  SS        +  P +P S      ++
Sbjct: 1615 TPPAVTPPS---PEKGPATPAPKGTPTSPPVTPSS-------LKDSPTSPASVTCKMGAT 1664

Query: 525  TSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQEGQEDGP 584
              QAS   PA +   A    +      S P   AP  KG  T  +   S  +       P
Sbjct: 1665 VPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPIC----PDP 1720

Query: 585  AGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTPVRPDR- 643
            +    +  P+   +PA   L P +  +    +  +A     G  A       TP+     
Sbjct: 1721 SAKNGSKGPLSTVAPA--PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAF 1778

Query: 644  ---TPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKK 700
                P+P S   S    +PSP        P SL +  + +   PP Q+    S       
Sbjct: 1779 EKVLPKPESASVS---AAPSP--------PVSLPLAPSPVPTLPPKQQFLPSS------- 1820

Query: 701  PHL-QGKPGRPLSPAN----VPALPGETVTSPV 728
            P L    P +PL+PA+    +P +P E ++  V
Sbjct: 1821 PGLVLESPSKPLAPADEDELLPLIPPEPISGGV 1853



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 118/516 (22%), Positives = 182/516 (35%), Gaps = 71/516 (13%)

Query: 243  PAAASASPKLTGLVPRQ-PGAMG----VDSRTSCSPQKAQEANKARPSAWEPAAGNSPAR 297
            PA    SPK T  +P   P + G      S+   +P  A  ++K  P+   P+    PA 
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAI 1395

Query: 298  ASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAA 357
             S    P   A    S   ++PA P     A TP++G + P              P    
Sbjct: 1396 PSPKGDPTSPAVIPLSPK-KAPATPVTREGAATPSKGDLTP--------------PAVTP 1440

Query: 358  AASHPAVPPSAPDPRPATPQGGGAPRV-----------AAPQTTLSSSSTSAATVDP--- 403
             +   A   SAP   PATP   G P +            AP+   +SSS   A   P   
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM 1500

Query: 404  -----PAWTPSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQ 458
                 PA  PS+ +   A     +    P  T LS +  TP+ +  K++        +  
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK--TPATLAPKEA-------LIPP 1551

Query: 459  ALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPA 518
            A++       PA   P  A  A PSS+  +  P  +P +    + SP+ L +P  +  P+
Sbjct: 1552 AMTVPSPKKTPAIPTPKEA-PATPSSKEASSPPAVTP-STYKGAPSPKELLIPPAVTSPS 1609

Query: 519  PLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDMSTSLQE 578
            P    + +  +  PP+  +  A  +  G         P  P +   S T    ++  +  
Sbjct: 1610 P--KEAPTPPAVTPPSPEKGPATPAPKGT----PTSPPVTPSSLKDSPTSPASVTCKMGA 1663

Query: 579  GQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSVHITLTP 638
                   G  A   P   +           P   A  R G   +K S         T  P
Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA--------TSPP 1715

Query: 639  VRPDRTPRPASPGP-SLPARSPSPPRRRRLAVPA-SLDVCDNWLRP-EPPGQEA----RV 691
            + PD + +  S GP S  A +P  P ++  +  A   D   +   P  PP  +A      
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA 1775

Query: 692  QSWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSP 727
             ++++   KP        P  P ++P  P    T P
Sbjct: 1776 AAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLP 1811



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 96/427 (22%), Positives = 139/427 (32%), Gaps = 74/427 (17%)

Query: 352 APCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSS-----SSTSAATVDPPAW 406
           +P   + +S P +P S P+   A    G    +  P ++++S     SS S    D  A 
Sbjct: 570 SPSFQSTSSSPEIPLS-PEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAG 628

Query: 407 TPSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEA 466
             SA    ++ +    T A  P  S    G  P+      +    A  FL+  +S   + 
Sbjct: 629 PDSAGPLLKS-SLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKN 687

Query: 467 GAPAPGR----PSPATAA----VPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPA 518
                G     P   TA+    V  S   T AP A+ +  P    S     LP    PP 
Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPG 747

Query: 519 PLSTSSTSQASALPP------------AGRRNLAESSGV--------GRVGAGSRPKPEA 558
                  S  SAL P            +G    A S G           +G    P+ + 
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKR 807

Query: 559 PMAKGKST---TLTQDMSTSLQ--------------EGQEDGPAGWRANLKPVDRRSPAE 601
           P  K  S    T   ++S+ +               +G +D PA   +   P  + +P  
Sbjct: 808 PPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTP 867

Query: 602 RTLKPKEPRALA-EPRAGEAPRKVSGSFAGSVHITLTPVRPDRTPRPASPGPSLPARSPS 660
             + P  P+ +   P+    P  V+  F         P     TP P    P+L   S S
Sbjct: 868 SAVTPLSPKGVTLPPKETPTPSVVNLPF---------PKEGPATPAP-KQAPALSMTSSS 917

Query: 661 PPRRRRLAVPASLDVCDNWLRPEPPGQEARVQSWKEEEKKPHLQGKPGRPLSPANVPALP 720
           P + R    P  +        P P G              P  +G P  P SP   P  P
Sbjct: 918 PKKARATPAPKGIPA-----SPSPKGAPT-----PPAATPPSPKGGPATP-SPKWAPTPP 966

Query: 721 GETVTSP 727
             T  SP
Sbjct: 967 AATPPSP 973



 Score = 38.5 bits (88), Expect = 0.029
 Identities = 79/331 (23%), Positives = 119/331 (35%), Gaps = 76/331 (22%)

Query: 284 PSAWEPAAGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNS 343
           P    PA    P  A+  A+P P+ ++  S  +  P   S S  A               
Sbjct: 46  PPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTA--------------- 90

Query: 344 SPMGWSSAAPCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDP 403
            P+G +  AP        P + P+A            +P +A    TL  + +S+A +  
Sbjct: 91  LPLGTAPEAPTFLPNLIGPPISPAA--------LALASPMIA---PTLKGTPSSSAPLAL 139

Query: 404 PAWTPSASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSAL 463
            A  P + +   A      TS  PP  +++  G    + LS   +  + +  L +  S +
Sbjct: 140 VALAPHSVQKSSAFPPNLLTS--PPSVAVAESGSV--ITLSAPIAPSEPKTNLNKVPSEV 195

Query: 464 EEAGAPAP-GRPSP--------------------ATAAVPSSQPKTEAPQASPLAKPLQS 502
                P P G PSP                      A++P + P T    ASP  K    
Sbjct: 196 ----VPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTI 251

Query: 503 SS-------PRVLGLPSRMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPK 555
           SS       P  L L   + PPA LS S+ S    LP      +  SS   +  AG    
Sbjct: 252 SSVLISPQNPGSLSLKGPVSPPAALSLSTQS----LP------VVTSS---QKTAGPNTP 298

Query: 556 PEAPMAKGKS-TTLTQDMSTSLQEGQEDGPA 585
           P+ P++ G     L Q    S+Q   + GP+
Sbjct: 299 PDFPISLGSHLAPLHQSSFGSVQLLGQTGPS 329



 Score = 34.7 bits (78), Expect = 0.41
 Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 8/71 (11%)

Query: 456 LKQALSALEEAGAPAPGRPSPATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRME 515
           +  ALS     G P P  P P + A P   P + A QASP   P   +S       + +E
Sbjct: 28  MSSALSVTAALGQPGPTLPPPCSPA-PQQCPLSAANQASPFPSPSTIAS-------TPLE 79

Query: 516 PPAPLSTSSTS 526
            P P S+S T+
Sbjct: 80  VPFPQSSSGTA 90



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 74/333 (22%), Positives = 117/333 (35%), Gaps = 60/333 (18%)

Query: 242 LPAAASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNSPARASVP 301
           +PA  +A P +   V + P  +   S  +CSP  +   N A   +  P         S+ 
Sbjct: 367 VPATVAAFPVVAPSVDKGPSTI---SSITCSPSGS--LNVATSFSLSPTT-------SLI 414

Query: 302 AAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAAPCTAAAASH 361
              +P AT     H    A+   S +  TP        VTN   +   +AAP T    + 
Sbjct: 415 LKSSPNAT----YHYPLVAQMPVSSVGTTPLV------VTNPCTI---AAAPTTTFEVAT 461

Query: 362 PAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVDPPAWTPSASRTQQARNKFF 421
              PP +  P         A  V AP      S+  A T+  P  +P     +  +N   
Sbjct: 462 CVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPV-SPPLPDPEDLKN--- 517

Query: 422 QTSAVPPGTSLSGRGPTPSLVLSKDSSKEQARNF---LKQALSALEEAGAPAPGRPS--P 476
                            PS VL K  +++  +     L+ A  +  +AG      P+  P
Sbjct: 518 ----------------LPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561

Query: 477 ATAAVPSSQPKTEAPQASPLAKPLQSSSPRVLGLPSRMEPPAPLSTSSTSQASALPPAGR 536
              A P + P  ++  +SP   PL   SP        +  P P+   ++S  S L     
Sbjct: 562 LVQAAPKNSPSFQSTSSSP-EIPL---SPEATLAKKSLGEPLPIGKPASSMTSPL----- 612

Query: 537 RNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLT 569
             +  S+ V +  + + P    P+ K    T T
Sbjct: 613 -GVNSSASVIKTDSYAGPDSAGPLLKSSLITPT 644


>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
          Length = 3639

 Score = 96.7 bits (239), Expect = 9e-20
 Identities = 47/100 (47%), Positives = 67/100 (67%), Gaps = 1/100 (1%)

Query: 6   ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
           AL  WC+++   Y +VNI + + S+ DGL F A++H HRPDL+++ +L+ +    N   A
Sbjct: 147 ALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLLDYGSLRPDRPLHNLAFA 206

Query: 66  FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNY 105
           F VAE+ LGI  LLD ED+ A + PD  SI+TYVS YY+Y
Sbjct: 207 FLVAEQELGIAQLLDPEDVAAAQ-PDERSIMTYVSLYYHY 245



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 9/120 (7%)

Query: 751  LDALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQ 810
            LD  EL G   EKR   +  D   D        LI++ Q L  QE   +Y S  + L++ 
Sbjct: 1598 LDVSELEGWVEEKRPLVSSRDYGRDEAAT--LRLINKHQAL--QEELAIYWSSMEELDQT 1653

Query: 811  QLDIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQ 870
               + G        PE  + +QER REQ    Q ++   DR         + LRE E+ Q
Sbjct: 1654 AQTLTGP-----EVPEQQRVVQERLREQLRALQELAATRDRELEGTLRLHEFLREAEDLQ 1708



 Score = 30.4 bits (67), Expect = 7.8
 Identities = 29/123 (23%), Positives = 53/123 (43%), Gaps = 14/123 (11%)

Query: 738  EEIQRQLQDIERRLDALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESE 797
            E+IQ +LQ +  + +AL  +  E    L+ A   +     + D    + + +  L+    
Sbjct: 1353 EDIQTRLQGLRSKWEALNRKMTERGDELQQAGQQEQLLRQLQDAKEQLEQLEGALQSSET 1412

Query: 798  LMYKSKAQRLEEQQLDIEGELRRLMAKPEALKSL--------------QERRREQELLEQ 843
                  +QRL+++   +E E R L AK  AL S+              Q+  R  ELL+ 
Sbjct: 1413 GQDLRSSQRLQKRHQQLESESRTLAAKMAALASMAHGMAASPAILEETQKHLRRLELLQG 1472

Query: 844  YVS 846
            +++
Sbjct: 1473 HLA 1475


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform
           5 [Homo sapiens]
          Length = 6907

 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 47/105 (44%), Positives = 71/105 (67%), Gaps = 1/105 (0%)

Query: 1   MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60
           M+A +AL  W ++QC  Y  VN+ +  +S+R+G+AF AI+H  RPDLI+  ++K  +  +
Sbjct: 181 MSARKALLLWAQEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKD 240

Query: 61  NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNY 105
           N + AFR+AE+ L IP LL+ ED V +  PD  SI+TYV+Q+  Y
Sbjct: 241 NLREAFRIAEQELKIPRLLEPED-VDVVDPDEKSIMTYVAQFLQY 284


>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform
           1 [Homo sapiens]
          Length = 6885

 Score = 94.0 bits (232), Expect = 6e-19
 Identities = 47/105 (44%), Positives = 71/105 (67%), Gaps = 1/105 (0%)

Query: 1   MAAIRALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYE 60
           M+A +AL  W ++QC  Y  VN+ +  +S+R+G+AF AI+H  RPDLI+  ++K  +  +
Sbjct: 181 MSARKALLLWAQEQCATYESVNVTDFKSSWRNGMAFLAIIHALRPDLIDMKSVKHRSNKD 240

Query: 61  NNKLAFRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNY 105
           N + AFR+AE+ L IP LL+ ED V +  PD  SI+TYV+Q+  Y
Sbjct: 241 NLREAFRIAEQELKIPRLLEPED-VDVVDPDEKSIMTYVAQFLQY 284


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,404,602
Number of Sequences: 37866
Number of extensions: 2852788
Number of successful extensions: 33092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 317
Number of HSP's successfully gapped in prelim test: 2347
Number of HSP's that attempted gapping in prelim test: 18095
Number of HSP's gapped (non-prelim): 12251
length of query: 904
length of database: 18,247,518
effective HSP length: 111
effective length of query: 793
effective length of database: 14,044,392
effective search space: 11137202856
effective search space used: 11137202856
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.