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Search of human proteins with 33457336
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
(796 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 1619 0.0
gi|24308115 interferon regulatory factor 2 binding protein 1 [Ho... 417 e-116
gi|116734704 interferon regulatory factor 2 binding protein 2 is... 300 3e-81
gi|116734706 interferon regulatory factor 2 binding protein 2 is... 300 5e-81
gi|55750053 atrophin-1 [Homo sapiens] 75 3e-13
gi|55750041 atrophin-1 [Homo sapiens] 75 3e-13
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 74 7e-13
gi|40354197 THAP domain containing 11 [Homo sapiens] 68 4e-11
gi|55956910 meningioma 1 [Homo sapiens] 67 8e-11
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 66 1e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 66 1e-10
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 64 4e-10
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 61 4e-09
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 61 4e-09
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 61 4e-09
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 61 5e-09
gi|226442791 runt-related transcription factor 2 isoform b [Homo... 60 6e-09
gi|226442783 runt-related transcription factor 2 isoform a [Homo... 60 6e-09
gi|66934969 runt-related transcription factor 2 isoform c [Homo ... 60 6e-09
gi|56549696 E1A binding protein p400 [Homo sapiens] 60 6e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens] 59 1e-08
gi|38158015 mastermind-like 3 [Homo sapiens] 59 1e-08
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 59 2e-08
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 59 2e-08
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 59 2e-08
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 59 2e-08
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 59 2e-08
gi|110347429 mediator complex subunit 12 [Homo sapiens] 58 4e-08
gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens] 58 4e-08
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 57 5e-08
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 1619 bits (4193), Expect = 0.0
Identities = 796/796 (100%), Positives = 796/796 (100%)
Query: 1 MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRA 60
MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRA
Sbjct: 1 MSAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRA 60
Query: 61 HGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQ 120
HGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQ
Sbjct: 61 HGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQ 120
Query: 121 QQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSL 180
QQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSL
Sbjct: 121 QQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSL 180
Query: 181 GSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLP 240
GSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLP
Sbjct: 181 GSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLP 240
Query: 241 NPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLG 300
NPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLG
Sbjct: 241 NPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLG 300
Query: 301 GTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSES 360
GTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSES
Sbjct: 301 GTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSES 360
Query: 361 LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLF 420
LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLF
Sbjct: 361 LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLF 420
Query: 421 IEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPE 480
IEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPE
Sbjct: 421 IEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYEKKHGSGDWRLLGDLLPE 480
Query: 481 AVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAAS 540
AVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAAS
Sbjct: 481 AVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAAS 540
Query: 541 LRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPP 600
LRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPP
Sbjct: 541 LRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPP 600
Query: 601 PPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSP 660
PPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSP
Sbjct: 601 PPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSP 660
Query: 661 VSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHE 720
VSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHE
Sbjct: 661 VSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHE 720
Query: 721 RLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEI 780
RLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEI
Sbjct: 721 RLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEI 780
Query: 781 ATILAGDVKVKKERDP 796
ATILAGDVKVKKERDP
Sbjct: 781 ATILAGDVKVKKERDP 796
>gi|24308115 interferon regulatory factor 2 binding protein 1 [Homo
sapiens]
Length = 584
Score = 417 bits (1072), Expect = e-116
Identities = 270/606 (44%), Positives = 338/606 (55%), Gaps = 105/606 (17%)
Query: 207 GPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPA 266
GPP L + +AAA+ +G P P G GG + Q +
Sbjct: 68 GPPALKHPATKDLAAAAA----QGPQLPPPQAQPQPSGTGG-------GVSGQDRYDRAT 116
Query: 267 SAAVLPPPPP---HALGSR-----GPPTPAPPGAPGGPACLGGTPGVSATS--SSASSST 316
S+ LP P P + LGSR G GA A LG PG+ ++A S
Sbjct: 117 SSGRLPLPSPALEYTLGSRLANGLGREEAVAEGARR--ALLGSMPGLMPPGLLAAAVSGL 174
Query: 317 SSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWASKPKMVR 376
S + G RP + +D E+E ++QRNA+ LAEL+E++R RAEEW +PK VR
Sbjct: 175 GSRGLTLAPGLSPARP--LFGSDFEKE--KQQRNADCLAELNEAMRGRAEEWHGRPKAVR 230
Query: 377 DTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKP-GMDYELKLFIEYPTGSGNVYSSAS 435
+ LL L+ C P+ VRFKKDH L+GRVFAFDA ++P G ++ELKLF EYP GSGNVY+
Sbjct: 231 EQLLALSACAPFNVRFKKDHGLVGRVFAFDATARPPGYEFELKLFTEYPCGSGNVYAGVL 290
Query: 436 GVAKQMYQDCMKDFGRGL-SSGFKYLEYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADM 494
VA+QM+ D +++ G+ L SSGFKYLEYE++HGSG+WR LG+LL + VR F+E P A+
Sbjct: 291 AVARQMFHDALREPGKALASSGFKYLEYERRHGSGEWRQLGELLTDGVRSFREPAP-AEA 349
Query: 495 LPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA 554
LPQ Y + AP+A G PP APS R A + R+RKASPEP A
Sbjct: 350 LPQQYPEP--------------APAALCGP---PPRAPS-RNLAPTPRRRKASPEPEGEA 391
Query: 555 EGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPE 614
G + EEQQ++ W+A P GP+S T
Sbjct: 392 AGKMTT-EEQQQRHWVA------------------------------PGGPYSAETP--- 417
Query: 615 SAPQNGPSPMAALMSVADTLGTAHSPKD----GSSVHSTTASARRNSSSPVSPASVPGQR 670
PSP+AAL +VA+ LG HSPKD G V + AS +S+ A P Q
Sbjct: 418 ----GVPSPIAALKNVAEALG--HSPKDPGGGGGPVRAGGASPAASST-----AQPPTQH 466
Query: 671 RLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLCCTICHERLEDTHFVQC 730
RL +RNG+ + + G + PLCCT+C ERLEDTHFVQC
Sbjct: 467 RLVARNGEAEVSPTAGAEAVSGGGS--------GTGATPGAPLCCTLCRERLEDTHFVQC 518
Query: 731 PSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKV 790
PSVP HKFCFPCSRE IKAQG GEVYCPSG+KCPLVGS+VPWAFMQGEIATILAGD+KV
Sbjct: 519 PSVPGHKFCFPCSREFIKAQGPAGEVYCPSGDKCPLVGSSVPWAFMQGEIATILAGDIKV 578
Query: 791 KKERDP 796
KKERDP
Sbjct: 579 KKERDP 584
Score = 123 bits (309), Expect = 6e-28
Identities = 75/167 (44%), Positives = 89/167 (53%), Gaps = 17/167 (10%)
Query: 4 AQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAHGC 63
A V +SRRQ CYLCDLP+MPWAM+WDFSE VCRGCVN+EGADRIE +I+ ARQLKR+H
Sbjct: 2 ASVQASRRQWCYLCDLPKMPWAMVWDFSEAVCRGCVNFEGADRIELLIDAARQLKRSH-V 60
Query: 64 FQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQ 123
+GRSPGPP A A AAAAAQ Q Q Q Q
Sbjct: 61 LPEGRSPGPP--------------ALKHPATKDLAAAAAQGPQLPPPQAQPQPSGTGGGV 106
Query: 124 QQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSR 170
Q + D ++ L PS Y L + A AV + +R
Sbjct: 107 SGQ--DRYDRATSSGRLPLPSPALEYTLGSRLANGLGREEAVAEGAR 151
>gi|116734704 interferon regulatory factor 2 binding protein 2
isoform A [Homo sapiens]
Length = 587
Score = 300 bits (768), Expect = 3e-81
Identities = 159/265 (60%), Positives = 186/265 (70%), Gaps = 22/265 (8%)
Query: 531 APSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPG 590
A + A + RKRK SPEP + G K+ E Q W++ +E LK+ M+
Sbjct: 344 ANGSKAVARTARKRKPSPEP-EGEVGPPKINGEAQ--PWLSTSTEGLKIPMTP------- 393
Query: 591 HAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTT 650
+ PPPP PHSNRTTPPE+A QNG SPMAAL+ VAD G +H+ KD + VHSTT
Sbjct: 394 -TSSFVSPPPPTASPHSNRTTPPEAA-QNGQSPMAALILVADNAGGSHASKDANQVHSTT 451
Query: 651 ASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANS 710
RRNS+SP SP+S+ QRRL R +V G++ VHP ++PDS +A S
Sbjct: 452 ---RRNSNSPPSPSSM-NQRRLGPR------EVGGQGAGNTGGLEPVHPASLPDSSLATS 501
Query: 711 GPLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSN 770
PLCCT+CHERLEDTHFVQCPSVPSHKFCFPCSR+SIK QGA+GEVYCPSGEKCPLVGSN
Sbjct: 502 APLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSN 561
Query: 771 VPWAFMQGEIATILAGDVKVKKERD 795
VPWAFMQGEIATILAGDVKVKKERD
Sbjct: 562 VPWAFMQGEIATILAGDVKVKKERD 586
Score = 209 bits (533), Expect = 6e-54
Identities = 171/443 (38%), Positives = 210/443 (47%), Gaps = 142/443 (32%)
Query: 2 SAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAH 61
+ A ++SRRQSCYLCDLPRMPWAMIWDF+EPVCRGCVNYEGADR+EFVIETARQLKRAH
Sbjct: 4 AVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAH 63
Query: 62 GCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQ 121
GCF +GRSP AAA+AAA +A +
Sbjct: 64 GCFPEGRSP----------------PGAAASAAAKPPPLSA---------------KDIL 92
Query: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAA---------AAAAAAAAVEQRSRFE 172
QQQQQL H + P AP LERY L+AAA ++ AA++ Q +
Sbjct: 93 LQQQQQLGHGGPEAAP---RAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQ 149
Query: 173 YPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTH 232
PPPV NG+ PNGF K E PPELNRQSPN RRG
Sbjct: 150 --PPPV------------NGILVPNGFSK---LEEPPELNRQSPN---------PRRGH- 182
Query: 233 GGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGA 292
VPP L+P L+NG A+ P P ALG
Sbjct: 183 ------------------AVPPTLVP--LMNGSAT------PLPTALG------------ 204
Query: 293 PGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSST------DQERELKE 346
LGG S + S +++ S A+ KRP SVSS+ +E KE
Sbjct: 205 ------LGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKE 258
Query: 347 KQ-------------RNAEALAELS-----ESLRNRAEEWASKPKMVRDTLLTL---AGC 385
KQ A AELS +S + ++W ++PK VRDTLL L
Sbjct: 259 KQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHS 318
Query: 386 TPYEVRFKKDHSL-LGRVFAFDA 407
P+E +FKK+ +L GR+ F+A
Sbjct: 319 GPFESKFKKEPALTAGRLLGFEA 341
Score = 37.0 bits (84), Expect = 0.072
Identities = 49/204 (24%), Positives = 66/204 (32%), Gaps = 36/204 (17%)
Query: 520 APPGTGALPPAAPSGRGAAASLRKRK-----ASPEPPDSAEGALKLGEEQQRQQWMANQS 574
+PPG A A P A L +++ PE A AL +R A
Sbjct: 71 SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQAL------ERYPLAAAAE 124
Query: 575 EALKLTMSAGGFAAPGHAAGGPPPPPPPLG--------------PHSNRTTPPESAPQNG 620
+L G A P P PPP+ P NR +P
Sbjct: 125 RPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAV 184
Query: 621 PSPMAALMSVADT-----LGTAHSPKDGSSVHSTTASARRNSSSPVS------PASVPGQ 669
P + LM+ + T LG + S TA+A S+ P PASV
Sbjct: 185 PPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSS 244
Query: 670 RRLASRNGDLNLQVAPPPPSAHPG 693
+ + + PPP AH G
Sbjct: 245 AAVEHEQREAAAKEKQPPPPAHRG 268
>gi|116734706 interferon regulatory factor 2 binding protein 2
isoform B [Homo sapiens]
Length = 571
Score = 300 bits (767), Expect = 5e-81
Identities = 159/264 (60%), Positives = 186/264 (70%), Gaps = 22/264 (8%)
Query: 532 PSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGH 591
P+ A + RKRK SPEP + G K+ E Q W++ +E LK+ M+
Sbjct: 329 PALTAVARTARKRKPSPEP-EGEVGPPKINGEAQ--PWLSTSTEGLKIPMTP-------- 377
Query: 592 AAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTA 651
+ PPPP PHSNRTTPPE+A QNG SPMAAL+ VAD G +H+ KD + VHSTT
Sbjct: 378 TSSFVSPPPPTASPHSNRTTPPEAA-QNGQSPMAALILVADNAGGSHASKDANQVHSTT- 435
Query: 652 SARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSG 711
RRNS+SP SP+S+ QRRL R +V G++ VHP ++PDS +A S
Sbjct: 436 --RRNSNSPPSPSSM-NQRRLGPR------EVGGQGAGNTGGLEPVHPASLPDSSLATSA 486
Query: 712 PLCCTICHERLEDTHFVQCPSVPSHKFCFPCSRESIKAQGATGEVYCPSGEKCPLVGSNV 771
PLCCT+CHERLEDTHFVQCPSVPSHKFCFPCSR+SIK QGA+GEVYCPSGEKCPLVGSNV
Sbjct: 487 PLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGASGEVYCPSGEKCPLVGSNV 546
Query: 772 PWAFMQGEIATILAGDVKVKKERD 795
PWAFMQGEIATILAGDVKVKKERD
Sbjct: 547 PWAFMQGEIATILAGDVKVKKERD 570
Score = 205 bits (522), Expect = 1e-52
Identities = 167/433 (38%), Positives = 204/433 (47%), Gaps = 141/433 (32%)
Query: 2 SAAQVSSSRRQSCYLCDLPRMPWAMIWDFSEPVCRGCVNYEGADRIEFVIETARQLKRAH 61
+ A ++SRRQSCYLCDLPRMPWAMIWDF+EPVCRGCVNYEGADR+EFVIETARQLKRAH
Sbjct: 4 AVAVAAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRVEFVIETARQLKRAH 63
Query: 62 GCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQ 121
GCF +GRSP AAA+AAA +A +
Sbjct: 64 GCFPEGRSP----------------PGAAASAAAKPPPLSA---------------KDIL 92
Query: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAA---------AAAAAAAAVEQRSRFE 172
QQQQQL H + P AP LERY L+AAA ++ AA++ Q +
Sbjct: 93 LQQQQQLGHGGPEAAP---RAPQALERYPLAAAAERPPRLGSDFGSSRPAASLAQPPTPQ 149
Query: 173 YPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTH 232
PPPV NG+ PNGF K E PPELNRQSPN RRG
Sbjct: 150 --PPPV------------NGILVPNGFSK---LEEPPELNRQSPN---------PRRGH- 182
Query: 233 GGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGA 292
VPP L+P L+NG A+ P P ALG
Sbjct: 183 ------------------AVPPTLVP--LMNGSAT------PLPTALG------------ 204
Query: 293 PGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSST------DQERELKE 346
LGG S + S +++ S A+ KRP SVSS+ +E KE
Sbjct: 205 ------LGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAVEHEQREAAAKE 258
Query: 347 KQ-------------RNAEALAELS-----ESLRNRAEEWASKPKMVRDTLLTL---AGC 385
KQ A AELS +S + ++W ++PK VRDTLL L
Sbjct: 259 KQPPPPAHRGPADSLSTAAGAAELSAEGAGKSRGSGEQDWVNRPKTVRDTLLALHQHGHS 318
Query: 386 TPYEVRFKKDHSL 398
P+E +FKK+ +L
Sbjct: 319 GPFESKFKKEPAL 331
Score = 37.0 bits (84), Expect = 0.072
Identities = 49/204 (24%), Positives = 66/204 (32%), Gaps = 36/204 (17%)
Query: 520 APPGTGALPPAAPSGRGAAASLRKRK-----ASPEPPDSAEGALKLGEEQQRQQWMANQS 574
+PPG A A P A L +++ PE A AL +R A
Sbjct: 71 SPPGAAASAAAKPPPLSAKDILLQQQQQLGHGGPEAAPRAPQAL------ERYPLAAAAE 124
Query: 575 EALKLTMSAGGFAAPGHAAGGPPPPPPPLG--------------PHSNRTTPPESAPQNG 620
+L G A P P PPP+ P NR +P
Sbjct: 125 RPPRLGSDFGSSRPAASLAQPPTPQPPPVNGILVPNGFSKLEEPPELNRQSPNPRRGHAV 184
Query: 621 PSPMAALMSVADT-----LGTAHSPKDGSSVHSTTASARRNSSSPVS------PASVPGQ 669
P + LM+ + T LG + S TA+A S+ P PASV
Sbjct: 185 PPTLVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSS 244
Query: 670 RRLASRNGDLNLQVAPPPPSAHPG 693
+ + + PPP AH G
Sbjct: 245 AAVEHEQREAAAKEKQPPPPAHRG 268
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.7 bits (182), Expect = 3e-13
Identities = 80/269 (29%), Positives = 101/269 (37%), Gaps = 44/269 (16%)
Query: 68 RSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQ 127
+ P PPPP G +A + A + A QQQQQQQQQQQQQQQQ
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
Query: 128 LNHVDGSSKPAVLAA-PSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHT 186
G+S P A P LE ++ A A + S YPP P L
Sbjct: 500 QQQHHGNSGPPPPGAFPHPLE----GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH-- 553
Query: 187 ARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGG 246
+++ GPNG P S ++SS++ S S +H P+ G G
Sbjct: 554 SQVSYSQAGPNGPPV------------SSSSNSSSSTSQGSYPCSHPS-----PSQGPQG 596
Query: 247 GPQLTVPP-----------NLLPQTLLNGPASAAVLPPPPPHALGSRGP-----PTPAPP 290
P PP + + T+ + PA PP P G R P T PP
Sbjct: 597 AP-YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPP 655
Query: 291 G-APGGPACL--GGTPGVSATSSSASSST 316
G PG P G PG TS A T
Sbjct: 656 GYKPGSPPSFRTGTPPGYRGTSPPAGPGT 684
Score = 46.6 bits (109), Expect = 9e-05
Identities = 46/155 (29%), Positives = 65/155 (41%), Gaps = 32/155 (20%)
Query: 191 NGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQL 250
+ +GGPNG + P P ++ S +S A + GG + P P P +
Sbjct: 242 SSVGGPNGGKQHPPPTTP--ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANF--PHV 297
Query: 251 TVPPNLLPQTLLNGPASAAVLPP-----------PPPHALGS----------RGP----- 284
T PNL P L +A+ PP P PHA+G +GP
Sbjct: 298 T--PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS 355
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSS 319
P PP + PA P S++SSSA++S+SSS
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 34/165 (20%)
Query: 172 EYPPP--PVSLGSSSHTARLPNG-----LGG--------PNGFPKPTPEEGPPELNRQSP 216
++PPP P+S+ SS + P +GG P FP TP PP R
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 217 NSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPP 276
N+S++ + ++ L LP+P G +PP GP L P P
Sbjct: 312 NASASPPGLGAQP-----LPGHLPSPHAMGQGMGGLPP---------GPEKGPTLAPSP- 356
Query: 277 HALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVA 321
H+L PAPP + SA +SS+SSS+SSS +
Sbjct: 357 HSLPPASSSAPAPPMR----FPYSSSSSSSAAASSSSSSSSSSAS 397
Score = 43.5 bits (101), Expect = 8e-04
Identities = 74/329 (22%), Positives = 117/329 (35%), Gaps = 54/329 (16%)
Query: 58 KRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQ-- 115
K A G ++ RS G P GV T + K + A A A + +Q + ++
Sbjct: 18 KEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEIS 77
Query: 116 ---------------QQQQQQQQQQQQLNHVDGSS-KPAVLAAPSGLERYGLSAAAAAAA 159
+Q+ + Q L+ +DG S + P +++ S + + +
Sbjct: 78 ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYS 137
Query: 160 AAAAAVEQRS---------RFEYPPP--PVSLGSSSHTARLPNGLGGPNGFPKPT----P 204
+ + S R +PPP P S T R P P+ PT P
Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAP 197
Query: 205 EEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTV---------PPN 255
E P Q+P + GT GG+++G P GGG +V PP
Sbjct: 198 MEPPTSRMFQAPPGAPPPHPQLYPGGT-GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 256 LLPQTLLNGPASAAVLPPPPPHALGSRGPPT-PAPPGAPGGPACLGGTPGVSATSSSASS 314
P ++ + AS A PP +G P+ P P P L P + +++++S
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 315 STS----------SSVAEVGVGAGGKRPG 333
S +G G GG PG
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Score = 39.3 bits (90), Expect = 0.015
Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 37/151 (24%)
Query: 175 PPPVSLGSSSHTARLPNGLG----------------GPNGFPKPTPEEGP---------- 208
PPP +L ++ + P GLG G G P P PE+GP
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP-PGPEKGPTLAPSPHSLP 360
Query: 209 ------PELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLL 262
P + P SSS+++S A+ + + P P P + P + P T L
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP--SYPHSFPPPTSL 418
Query: 263 N--GPASAAVLPPPPPHALGSRGPPTPAPPG 291
+ P P A+ S+GPP P P G
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG 449
Score = 36.2 bits (82), Expect = 0.12
Identities = 54/237 (22%), Positives = 77/237 (32%), Gaps = 62/237 (26%)
Query: 490 PGADMLPQPYLDAS---CPMLPTALVSLSRAPSAPP--------GTGAL---PPAAPSGR 535
P A P P + + PM P P APP GTG + PP P G
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238
Query: 536 GAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGG 595
GAA+S+ + P +++S+ G A G
Sbjct: 239 GAASSVGGPNGGKQHPPPTT----------------------PISVSSSG-------ASG 269
Query: 596 PPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARR 655
PP PP P P P N P L P +++ +AS
Sbjct: 270 APPTKPPTTPVGGGNLPSAPPPANFPHVTPNL----------PPPPALRPLNNASASPPG 319
Query: 656 NSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGP 712
+ P+ P +P + G L PP P P + P ++P P ++S P
Sbjct: 320 LGAQPL-PGHLPSPHAMGQGMGGL-----PPGPEKGPTL-APSPHSLP--PASSSAP 367
Score = 35.8 bits (81), Expect = 0.16
Identities = 54/204 (26%), Positives = 72/204 (35%), Gaps = 46/204 (22%)
Query: 505 PMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA-----EGALK 559
P LP+ V S+ P PP G L + + G +++ PP S + +
Sbjct: 430 PSLPSQAV-WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488
Query: 560 LGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPP---PPPL-GPHSNRTTPPES 615
++QQ+QQ Q H GPPPP P PL G S+ P
Sbjct: 489 QQQQQQQQQQQQQQH----------------HGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532
Query: 616 APQNG---PSPMAALMSVADTLGTAHSPKDGSSVHSTTA-------SARRNSSSPVSPAS 665
+P G P P G AH P S V + A S+ NSSS S S
Sbjct: 533 SPSLGSLRPYPP----------GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 666 VPGQRRLASRNGDLNLQVAPPPPS 689
P S+ PP P+
Sbjct: 583 YPCSHPSPSQGPQGAPYPFPPVPT 606
Score = 33.9 bits (76), Expect = 0.61
Identities = 58/234 (24%), Positives = 87/234 (37%), Gaps = 57/234 (24%)
Query: 134 SSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYP-PPPVSLGSSSHTARLPNG 192
S PA +AP+ R+ S++++++AAA+++ S P P +L S H+ P
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 193 LGGPNGFPKPT----PEEG--------PPELNRQSPNSSSAAA----SVASRRGTHGGLV 236
L N PK T P + PP R NS++ S ++ H +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
Query: 237 T---------------------GLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPP 275
T + G G P PP P L G +S P
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP----PPGAFPHP-LEGGSSHHAHPYAM 532
Query: 276 PHALGSRGPPTPAPPGAP----------GGPACLGGTPGVSATSSSASSSTSSS 319
+LGS P P P P GP P VS++S+S+SS++ S
Sbjct: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGP----NGPPVSSSSNSSSSTSQGS 582
Score = 32.0 bits (71), Expect = 2.3
Identities = 49/225 (21%), Positives = 75/225 (33%), Gaps = 33/225 (14%)
Query: 498 PYLDASCPMLPTALVSLSRAPSAPPGTGA--LPPAAPSGRGAAASLRKRKASPE------ 549
P++ + P P AL L+ A ++PPG GA LP PS + PE
Sbjct: 295 PHVTPNLPP-PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 550 ------PPDSAEG---ALKLGEEQQRQQWMANQSEALKLTMSAGGF----AAPGHAAGGP 596
PP S+ ++ A S + + SA F A P + P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 597 PPPPPPLGPHSNRTTPPESAPQ-------NGPSPMAALMSVADTLGTAHSPKDG--SSVH 647
PP + + T P Q P P L++ ++ P G S+ H
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 648 STTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHP 692
++ + Q++ + N PPPP A P
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN--SGPPPPGAFP 516
Score = 32.0 bits (71), Expect = 2.3
Identities = 40/173 (23%), Positives = 53/173 (30%), Gaps = 29/173 (16%)
Query: 496 PQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAE 555
P P + S L T + +++ S+P G P P G A + PP
Sbjct: 603 PVPTVTTSSATLSTVIATVA---SSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP 659
Query: 556 GALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHS-NRTTPPE 614
G+ + A G PG GP P PP GP PP
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPA------GPGTFKPGSPTVGPGPLPP-AGPSGLPSLPPPP 712
Query: 615 SAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVP 667
+AP +GP P + + A SPV PA P
Sbjct: 713 AAPASGP------------------PLSATQIKQEPAEEYETPESPVPPARSP 747
Score = 31.2 bits (69), Expect = 4.0
Identities = 27/122 (22%), Positives = 38/122 (31%)
Query: 591 HAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTT 650
++ GP PP +S+ +T S P + PSP + S+ ST
Sbjct: 558 YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
Query: 651 ASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANS 710
+ +S + AS PG R PP PG P S
Sbjct: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 711 GP 712
P
Sbjct: 678 PP 679
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 74.7 bits (182), Expect = 3e-13
Identities = 80/269 (29%), Positives = 101/269 (37%), Gaps = 44/269 (16%)
Query: 68 RSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQ 127
+ P PPPP G +A + A + A QQQQQQQQQQQQQQQQ
Sbjct: 440 QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499
Query: 128 LNHVDGSSKPAVLAA-PSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHT 186
G+S P A P LE ++ A A + S YPP P L
Sbjct: 500 QQQHHGNSGPPPPGAFPHPLE----GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPH-- 553
Query: 187 ARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGG 246
+++ GPNG P S ++SS++ S S +H P+ G G
Sbjct: 554 SQVSYSQAGPNGPPV------------SSSSNSSSSTSQGSYPCSHPS-----PSQGPQG 596
Query: 247 GPQLTVPP-----------NLLPQTLLNGPASAAVLPPPPPHALGSRGP-----PTPAPP 290
P PP + + T+ + PA PP P G R P T PP
Sbjct: 597 AP-YPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPP 655
Query: 291 G-APGGPACL--GGTPGVSATSSSASSST 316
G PG P G PG TS A T
Sbjct: 656 GYKPGSPPSFRTGTPPGYRGTSPPAGPGT 684
Score = 46.6 bits (109), Expect = 9e-05
Identities = 46/155 (29%), Positives = 65/155 (41%), Gaps = 32/155 (20%)
Query: 191 NGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQL 250
+ +GGPNG + P P ++ S +S A + GG + P P P +
Sbjct: 242 SSVGGPNGGKQHPPPTTP--ISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANF--PHV 297
Query: 251 TVPPNLLPQTLLNGPASAAVLPP-----------PPPHALGS----------RGP----- 284
T PNL P L +A+ PP P PHA+G +GP
Sbjct: 298 T--PNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPS 355
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSS 319
P PP + PA P S++SSSA++S+SSS
Sbjct: 356 PHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSS 390
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/165 (29%), Positives = 68/165 (41%), Gaps = 34/165 (20%)
Query: 172 EYPPP--PVSLGSSSHTARLPNG-----LGG--------PNGFPKPTPEEGPPELNRQSP 216
++PPP P+S+ SS + P +GG P FP TP PP R
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311
Query: 217 NSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPP 276
N+S++ + ++ L LP+P G +PP GP L P P
Sbjct: 312 NASASPPGLGAQP-----LPGHLPSPHAMGQGMGGLPP---------GPEKGPTLAPSP- 356
Query: 277 HALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVA 321
H+L PAPP + SA +SS+SSS+SSS +
Sbjct: 357 HSLPPASSSAPAPPMR----FPYSSSSSSSAAASSSSSSSSSSAS 397
Score = 43.5 bits (101), Expect = 8e-04
Identities = 74/329 (22%), Positives = 117/329 (35%), Gaps = 54/329 (16%)
Query: 58 KRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQ-- 115
K A G ++ RS G P GV T + K + A A A + +Q + ++
Sbjct: 18 KEAPGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEIS 77
Query: 116 ---------------QQQQQQQQQQQQLNHVDGSS-KPAVLAAPSGLERYGLSAAAAAAA 159
+Q+ + Q L+ +DG S + P +++ S + + +
Sbjct: 78 ESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYS 137
Query: 160 AAAAAVEQRS---------RFEYPPP--PVSLGSSSHTARLPNGLGGPNGFPKPT----P 204
+ + S R +PPP P S T R P P+ PT P
Sbjct: 138 PGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAP 197
Query: 205 EEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTV---------PPN 255
E P Q+P + GT GG+++G P GGG +V PP
Sbjct: 198 MEPPTSRMFQAPPGAPPPHPQLYPGGT-GGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256
Query: 256 LLPQTLLNGPASAAVLPPPPPHALGSRGPPT-PAPPGAPGGPACLGGTPGVSATSSSASS 314
P ++ + AS A PP +G P+ P P P L P + +++++S
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASAS 316
Query: 315 STS----------SSVAEVGVGAGGKRPG 333
S +G G GG PG
Sbjct: 317 PPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345
Score = 39.3 bits (90), Expect = 0.015
Identities = 40/151 (26%), Positives = 57/151 (37%), Gaps = 37/151 (24%)
Query: 175 PPPVSLGSSSHTARLPNGLG----------------GPNGFPKPTPEEGP---------- 208
PPP +L ++ + P GLG G G P P PE+GP
Sbjct: 302 PPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP-PGPEKGPTLAPSPHSLP 360
Query: 209 ------PELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLL 262
P + P SSS+++S A+ + + P P P + P + P T L
Sbjct: 361 PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP--SYPHSFPPPTSL 418
Query: 263 N--GPASAAVLPPPPPHALGSRGPPTPAPPG 291
+ P P A+ S+GPP P P G
Sbjct: 419 SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYG 449
Score = 36.2 bits (82), Expect = 0.12
Identities = 54/237 (22%), Positives = 77/237 (32%), Gaps = 62/237 (26%)
Query: 490 PGADMLPQPYLDAS---CPMLPTALVSLSRAPSAPP--------GTGAL---PPAAPSGR 535
P A P P + + PM P P APP GTG + PP P G
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGG 238
Query: 536 GAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGG 595
GAA+S+ + P +++S+ G A G
Sbjct: 239 GAASSVGGPNGGKQHPPPTT----------------------PISVSSSG-------ASG 269
Query: 596 PPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARR 655
PP PP P P P N P L P +++ +AS
Sbjct: 270 APPTKPPTTPVGGGNLPSAPPPANFPHVTPNL----------PPPPALRPLNNASASPPG 319
Query: 656 NSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGP 712
+ P+ P +P + G L PP P P + P ++P P ++S P
Sbjct: 320 LGAQPL-PGHLPSPHAMGQGMGGL-----PPGPEKGPTL-APSPHSLP--PASSSAP 367
Score = 35.8 bits (81), Expect = 0.16
Identities = 54/204 (26%), Positives = 72/204 (35%), Gaps = 46/204 (22%)
Query: 505 PMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA-----EGALK 559
P LP+ V S+ P PP G L + + G +++ PP S + +
Sbjct: 430 PSLPSQAV-WSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQ 488
Query: 560 LGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPP---PPPL-GPHSNRTTPPES 615
++QQ+QQ Q H GPPPP P PL G S+ P
Sbjct: 489 QQQQQQQQQQQQQQH----------------HGNSGPPPPGAFPHPLEGGSSHHAHPYAM 532
Query: 616 APQNG---PSPMAALMSVADTLGTAHSPKDGSSVHSTTA-------SARRNSSSPVSPAS 665
+P G P P G AH P S V + A S+ NSSS S S
Sbjct: 533 SPSLGSLRPYPP----------GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGS 582
Query: 666 VPGQRRLASRNGDLNLQVAPPPPS 689
P S+ PP P+
Sbjct: 583 YPCSHPSPSQGPQGAPYPFPPVPT 606
Score = 33.9 bits (76), Expect = 0.61
Identities = 58/234 (24%), Positives = 87/234 (37%), Gaps = 57/234 (24%)
Query: 134 SSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYP-PPPVSLGSSSHTARLPNG 192
S PA +AP+ R+ S++++++AAA+++ S P P +L S H+ P
Sbjct: 358 SLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTS 417
Query: 193 LGGPNGFPKPT----PEEG--------PPELNRQSPNSSSAAA----SVASRRGTHGGLV 236
L N PK T P + PP R NS++ S ++ H +
Sbjct: 418 LSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVS 477
Query: 237 T---------------------GLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPP 275
T + G G P PP P L G +S P
Sbjct: 478 THHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP----PPGAFPHP-LEGGSSHHAHPYAM 532
Query: 276 PHALGSRGPPTPAPPGAP----------GGPACLGGTPGVSATSSSASSSTSSS 319
+LGS P P P P GP P VS++S+S+SS++ S
Sbjct: 533 SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGP----NGPPVSSSSNSSSSTSQGS 582
Score = 32.0 bits (71), Expect = 2.3
Identities = 49/225 (21%), Positives = 75/225 (33%), Gaps = 33/225 (14%)
Query: 498 PYLDASCPMLPTALVSLSRAPSAPPGTGA--LPPAAPSGRGAAASLRKRKASPE------ 549
P++ + P P AL L+ A ++PPG GA LP PS + PE
Sbjct: 295 PHVTPNLPP-PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353
Query: 550 ------PPDSAEG---ALKLGEEQQRQQWMANQSEALKLTMSAGGF----AAPGHAAGGP 596
PP S+ ++ A S + + SA F A P + P
Sbjct: 354 PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFP 413
Query: 597 PPPPPPLGPHSNRTTPPESAPQ-------NGPSPMAALMSVADTLGTAHSPKDG--SSVH 647
PP + + T P Q P P L++ ++ P G S+ H
Sbjct: 414 PPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAH 473
Query: 648 STTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHP 692
++ + Q++ + N PPPP A P
Sbjct: 474 PPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGN--SGPPPPGAFP 516
Score = 32.0 bits (71), Expect = 2.3
Identities = 40/173 (23%), Positives = 53/173 (30%), Gaps = 29/173 (16%)
Query: 496 PQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAE 555
P P + S L T + +++ S+P G P P G A + PP
Sbjct: 603 PVPTVTTSSATLSTVIATVA---SSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKP 659
Query: 556 GALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHS-NRTTPPE 614
G+ + A G PG GP P PP GP PP
Sbjct: 660 GSPPSFRTGTPPGYRGTSPPA------GPGTFKPGSPTVGPGPLPP-AGPSGLPSLPPPP 712
Query: 615 SAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVP 667
+AP +GP P + + A SPV PA P
Sbjct: 713 AAPASGP------------------PLSATQIKQEPAEEYETPESPVPPARSP 747
Score = 31.2 bits (69), Expect = 4.0
Identities = 27/122 (22%), Positives = 38/122 (31%)
Query: 591 HAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTT 650
++ GP PP +S+ +T S P + PSP + S+ ST
Sbjct: 558 YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTV 617
Query: 651 ASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANS 710
+ +S + AS PG R PP PG P S
Sbjct: 618 IATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTS 677
Query: 711 GP 712
P
Sbjct: 678 PP 679
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 73.6 bits (179), Expect = 7e-13
Identities = 92/372 (24%), Positives = 133/372 (35%), Gaps = 45/372 (12%)
Query: 65 QDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQ 124
Q +SP P + +L AA + A + +QQQ QQQQQQ + +
Sbjct: 37 QRAQSPARP-----RDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGP 91
Query: 125 QQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPP-------- 176
+ G ++ A AP G + A A AA AA + PP
Sbjct: 92 PASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELE 151
Query: 177 --------PVSLGSSSHTARLPNGLGG-----PNGFPKPTPEEG--------------PP 209
P LG G GG G P+P P G
Sbjct: 152 SVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGG 211
Query: 210 ELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAA 269
E SP+SSSA + + G V G + GGG + + L Q L +AA
Sbjct: 212 EGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAA 271
Query: 270 VLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGG 329
HA G + + P G PA SA+ +A++ AE GG
Sbjct: 272 AAAAAQMHAKNGGGSSSRSSP-VSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGG 330
Query: 330 KR----PGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWASKPKMVRDTLLTLAGC 385
+ P S Q +E +E Q E L E +E+L+N +E ++ +RDT C
Sbjct: 331 MQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDAC 390
Query: 386 TPYEVRFKKDHS 397
E+R + + +
Sbjct: 391 QLQEMRHELERA 402
Score = 40.0 bits (92), Expect = 0.009
Identities = 44/139 (31%), Positives = 50/139 (35%), Gaps = 17/139 (12%)
Query: 518 PSAPPGT--GALPP-----AAPSGRGAAASLRKRKASPEPPDSAEGA-LKLGEEQQRQQW 569
P AP G GA+ P AAP+ AA R+ EPP E KLGE +
Sbjct: 107 PLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEG 166
Query: 570 MANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSN--RTTPPESAPQNGPSPMAAL 627
E G G GG P PPPP G R + G SP +
Sbjct: 167 GGGGGEG------GGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSS 220
Query: 628 MSVADTLGTAHSPKDGSSV 646
S T GT S GS V
Sbjct: 221 SSAGKTPGTG-SRNSGSGV 238
>gi|40354197 THAP domain containing 11 [Homo sapiens]
Length = 314
Score = 67.8 bits (164), Expect = 4e-11
Identities = 68/203 (33%), Positives = 88/203 (43%), Gaps = 30/203 (14%)
Query: 53 TARQLKRAHGCFQDGRSPGPPPPVGVKTV-ALSAKEAAAAAAAAAAAAAAAQQQQQQQQQ 111
T +L H FQ GR V V T+ L A A AAAA ++QQQQQQQ
Sbjct: 56 TGHRLCSVH--FQGGRKTYT---VRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQ 110
Query: 112 QQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVE-QRSR 170
QQQQQQQQQQQQQQQQ SS A A + L+ +SA+AA A V+ ++
Sbjct: 111 QQQQQQQQQQQQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTLQATVDSSQAP 170
Query: 171 FEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPP-ELNRQSPNSSSAAASVASRR 229
P P++ PT E+ P +L Q +++ A+ A+
Sbjct: 171 GSVQPAPIT----------------------PTGEDVKPIDLTVQVEFAAAEGAAAAAAA 208
Query: 230 GTHGGLVTGLPNPGGGGGPQLTV 252
GL GPQL V
Sbjct: 209 SELQAATAGLEAAECPMGPQLVV 231
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 66.6 bits (161), Expect = 8e-11
Identities = 80/258 (31%), Positives = 91/258 (35%), Gaps = 62/258 (24%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAA 162
QQQQQQQQQQQQQQQQQQQQQQQQQ AA
Sbjct: 523 QQQQQQQQQQQQQQQQQQQQQQQQQQQQRQN---------------------AALMIKQM 561
Query: 163 AAVEQRSRFEYP-------PPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQS 215
A+ Q+ R P P V G H + GL PN F + G L
Sbjct: 562 ASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPV-GGLAQPN-FEREGGSTGAGRLGTFE 619
Query: 216 PNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPP 275
+ A A G H LP GG G LP GP ++ PPPP
Sbjct: 620 QQAPHLAQESAWFSGPHPPPGDLLPRRMGGSG---------LPADC--GPHDPSLAPPPP 668
Query: 276 PHALG--SRGP-------------PTPAPPGAPGGPACLGG-----TPGVSATSSSASSS 315
P G RGP P PG G LGG +PG SA+S
Sbjct: 669 PGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFG-GSLGGLGQLQSPGAGVGLPSAASE 727
Query: 316 TSSSVAEVGVGAGGKRPG 333
+ A G +PG
Sbjct: 728 RRPPPPDFATSALGGQPG 745
Score = 66.6 bits (161), Expect = 8e-11
Identities = 87/273 (31%), Positives = 98/273 (35%), Gaps = 56/273 (20%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQ--------------------------QLNHV-DGSS 135
QQQQQQQQQQQQQQQQQQQQQQQQ QL H D
Sbjct: 527 QQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQ 586
Query: 136 KPAVLAAPSG------LERYGLSAAAAAAAA----AAAAVEQRSRFEYP-PPPVSLGSSS 184
V P G ER G S A A ++ + F P PPP L
Sbjct: 587 GGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDL---- 642
Query: 185 HTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSA---AASVASRRGTHGGLVTGLPN 241
LP +GG +G P P P S R G V LP+
Sbjct: 643 ----LPRRMGG-SGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPS 697
Query: 242 PGGGGGPQLTVPPNLLPQTLLNGPASAAV--LPPPPPHALGSRGPPTPAPPGAPGGPACL 299
PG G L L G SAA PPPP A + G P GA G +
Sbjct: 698 PGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTP 757
Query: 300 GGTPGVSATSSSASSSTSSSVAEVGVGAGGKRP 332
PGV++ S+ SS G G GG P
Sbjct: 758 HSGPGVNSPPSAGGGGGSSG----GGGGGGAYP 786
Score = 47.8 bits (112), Expect = 4e-05
Identities = 43/131 (32%), Positives = 54/131 (41%), Gaps = 5/131 (3%)
Query: 89 AAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQL--NHVDGSSKPAVLAAPSGL 146
A+A AA ++ Q QQQ QQQQQ QQQQQQ + G+ K V PS
Sbjct: 273 ASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVG 332
Query: 147 ERYGL-SAAAAAAAAAAAAVEQRSRFEYPPPPVSL--GSSSHTARLPNGLGGPNGFPKPT 203
R+ L A Q+ + PPPP L +S LP G G P
Sbjct: 333 SRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGG 392
Query: 204 PEEGPPELNRQ 214
++G P L Q
Sbjct: 393 LQDGGPMLPSQ 403
Score = 36.2 bits (82), Expect = 0.12
Identities = 50/197 (25%), Positives = 63/197 (31%), Gaps = 41/197 (20%)
Query: 518 PSAPPGTGALPPAAPSGRGAAASLRKRKAS--PEPPDSAEGALKLGEEQQRQQWM----- 570
P PPG L P G G A S P PP G L G Q+ +
Sbjct: 635 PHPPPGD--LLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHV 692
Query: 571 -ANQSEALKLTMSAGGFA---APGHAAGGPP------PPPPPLGPHSNRTTPP------- 613
A S L+ S GG +PG G P PPPP + P
Sbjct: 693 PALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAG 752
Query: 614 -ESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRL 672
+S P +GP +SP ++ + P P P QR
Sbjct: 753 RQSTPHSGPG--------------VNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTS 798
Query: 673 ASRNGDLNLQVAPPPPS 689
AS+ G L+L P S
Sbjct: 799 ASKLGALSLGSFNKPSS 815
Score = 35.0 bits (79), Expect = 0.27
Identities = 29/109 (26%), Positives = 39/109 (35%), Gaps = 13/109 (11%)
Query: 522 PGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTM 581
PG A+P AA L K A P + ++QQ + S A K+ +
Sbjct: 271 PGASAMPRAA-----GMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPV 325
Query: 582 SAGGFAAPGHAAGGPPP--PPPPLGPHSNRTTPPESAPQNGPSPMAALM 628
H PP PPPP + PP+ PQ P P L+
Sbjct: 326 GLEPSVGSRHPLMQPPQQAPPPP------QQQPPQQPPQQQPPPPPGLL 368
Score = 34.3 bits (77), Expect = 0.47
Identities = 61/280 (21%), Positives = 95/280 (33%), Gaps = 28/280 (10%)
Query: 64 FQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQ----- 118
F G +PG P P G + S +A+ A + + +
Sbjct: 879 FPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGG 938
Query: 119 --QQQQQQQQQLNHVD-GSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPP 175
+ + ++++ HV G+ AAP G+S A+ AA P
Sbjct: 939 GGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP 998
Query: 176 PPVSLGSSSHTARLPNGLGGPNGFPKPTPE-----EGPPELNRQSPNSSSAAAS-VASRR 229
P +S P+ G P+ +G + + SPN A+ V++
Sbjct: 999 TPHEKALTS-----PSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSY 1053
Query: 230 GTHGGLVTGLPNPGG----GGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALG--SRG 283
+ + NP P +T P L P+ + G PPP LG S
Sbjct: 1054 ANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGV--GAGEHGPKAPPPALGLGIMSNS 1111
Query: 284 PPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEV 323
TP G GGP GTPG+ + SSS + E+
Sbjct: 1112 TSTPDSYGGGGGPG-HPGTPGLEQVRTPTSSSGAPPPDEI 1150
Score = 30.8 bits (68), Expect = 5.2
Identities = 30/141 (21%), Positives = 50/141 (35%), Gaps = 13/141 (9%)
Query: 559 KLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSN---RTTPPES 615
K + +++ N+++ + + G PG A G P P P G S+ + PP
Sbjct: 850 KKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNP 909
Query: 616 APQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASR 675
Q + ++ ++ T G P G R+ S VSP + + A
Sbjct: 910 PAQGDGTSLSPNYTLESTSGNDGKPVSGGG--GRGRGRRKRDSGHVSPGTFFDKYSAAPD 967
Query: 676 NGDLNLQVAPPPPSAHPGMDQ 696
+G P PG Q
Sbjct: 968 SGG--------APGVSPGQQQ 980
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 66.2 bits (160), Expect = 1e-10
Identities = 81/297 (27%), Positives = 113/297 (38%), Gaps = 48/297 (16%)
Query: 69 SPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQL 128
+P PPPP +K +E A AAAAAAA + + Q+ +
Sbjct: 15 NPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESE--------------- 59
Query: 129 NHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVE---QRSRFEYPPPPVSLGSSSH 185
G +P G E G A + E + S P P +++
Sbjct: 60 GPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRP---ALNNN 116
Query: 186 TARLPNGLGGPN----GFPK-------PTPEEGPPELNRQSPNSSSAAASVASRRGTHGG 234
P G GG + G P P P G + +SP S+ AAA+ A HGG
Sbjct: 117 LTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP-SAVAAAAAAVFHQQHGG 175
Query: 235 L----VTGLPNPGGGG-----GPQLTVPPNLLPQTLLNG--PASAAVLPPPPPHALGSRG 283
+ L + GGGG GPQ + P N P +A PP P +AL S
Sbjct: 176 QQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS-- 233
Query: 284 PPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQ 340
P PG+ G A G P S+++S++SSS+S + G GG + T Q
Sbjct: 234 -PRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288
Score = 58.9 bits (141), Expect = 2e-08
Identities = 165/752 (21%), Positives = 238/752 (31%), Gaps = 168/752 (22%)
Query: 56 QLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQ 115
++K A G +G + GPP P+G + + A + + +
Sbjct: 49 EMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG 108
Query: 116 QQQQQQQQQQQQLNHVDGSSKPAVLAAPSGL------------ERYGLSAAAAAAAAAAA 163
+ + G S V A P + YG S +A AAAAAA
Sbjct: 109 PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168
Query: 164 AVEQRSRFEYP-------------PPPVSLGSSSHTARLPNGLGG---PN--GFPKP--- 202
+Q + P P +SH PN PN +P P
Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA 228
Query: 203 ----TPEEGPP------ELNRQSPNSSSAAASVAS------RRGTHGGLVTGLPNPGGGG 246
+P G P + P SSSA+AS +S R G GG G P+ GGG
Sbjct: 229 YALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG---GGPSAAGGG 285
Query: 247 GPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVS 306
PQ T P L LL P+SA P G P GA GPA + +
Sbjct: 286 TPQPTATPTL--NQLLTSPSSARGYQGYP----GGDYSGGPQDGGAGKGPADMASQCWGA 339
Query: 307 ATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAE 366
A +++A+++ S + A PGS Q R + + + + + R +
Sbjct: 340 AAAAAAAAAASGGAQQRSHHA-PMSPGSSGGGGQ-----PLARTPQPSSPMDQMGKMRPQ 393
Query: 367 EWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYP-T 425
+ G PY + PG Y + YP T
Sbjct: 394 PY--------------GGTNPYSQQQGPPSG------PQQGHGYPGQPYGSQTPQRYPMT 433
Query: 426 GSGNVYSSASGVAKQMYQDCMKDFGRGLSSGF------KYLEYEKKHGSGDWRLLGDLLP 479
G S+ G++ Y + +G+ SG+ Y + H P
Sbjct: 434 MQGRAQSAMGGLS---YTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 480 EAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPP-------------GTGA 526
P A Q + P L ++ S+ PS PP T
Sbjct: 491 SQ-------TPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543
Query: 527 LPPAAPSGRGAAASLRKRKASPEPPD----SAEGALKLGEEQQRQQWMANQ--------- 573
P + P A ++ P+ P S + A + QQ QQ +Q
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603
Query: 574 ---------SEALKLTMSAGGFAAPGHAAGGPPPPPPPL-GPHSNRTTPPESAPQNGPSP 623
S A +T S GG + P P L G + E A G S
Sbjct: 604 SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663
Query: 624 MAALMSVADTLGTAHSP-KDGSSVH------------STTASARRNSSSPVSPASVPGQR 670
S + A SP +S H + AS ++ S P+SPA+VPG
Sbjct: 664 SGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN- 722
Query: 671 RLASRNGDLNLQVAPPPPSA------HPGMDQ 696
Q+ P PPS HP M+Q
Sbjct: 723 -----------QMPPRPPSGQSDSIMHPSMNQ 743
Score = 34.3 bits (77), Expect = 0.47
Identities = 48/217 (22%), Positives = 71/217 (32%), Gaps = 43/217 (19%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAA 162
QQQ Q Q QQQ Q QQ + + G++ PA +A AA A
Sbjct: 1402 QQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPA-------------TATAATERRPA 1448
Query: 163 AAVEQRSRFEYPPPPVSL--GSSSHTARLPNGLGGPNGFPKPTPEEGP----------PE 210
+ + F++ VS G+++ P +GGP ++G
Sbjct: 1449 GGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVAQQGTMWQGRNDMTYNY 1508
Query: 211 LNRQSPNSSSAAASV-----------ASRRGTHGGLVTGLPNPGGGGGPQLTVPP----- 254
NRQS S+ + +R H G GP VPP
Sbjct: 1509 ANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGPSAPVPPMTRPP 1568
Query: 255 --NLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAP 289
N P + P P P + +R P+ +P
Sbjct: 1569 PSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSP 1605
Score = 30.8 bits (68), Expect = 5.2
Identities = 44/190 (23%), Positives = 67/190 (35%), Gaps = 51/190 (26%)
Query: 103 QQQQQQQQQQQ------------------QQQQQQQQQQQQQQLNHVDGSSKPAVLAAPS 144
QQQQQQQQ+ QQ QQQQQ +DG+ P A
Sbjct: 1327 QQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPP--AKRH 1384
Query: 145 GLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTP 204
E Y + + Q + + PP S A +P+P
Sbjct: 1385 EGEMYSVPYSTGQG--------QPQQQQLPPAQPQPASQQQAA-------------QPSP 1423
Query: 205 EEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNL-----LPQ 259
++ ++ Q N+ A A+ A+ R GG P G +++ PP +P
Sbjct: 1424 QQ---DVYNQYGNAYPATATAATERRPAGGPQNQFPFQ--FGRDRVSAPPGTNAQQNMPP 1478
Query: 260 TLLNGPASAA 269
++ GP A+
Sbjct: 1479 QMMGGPIQAS 1488
Score = 30.0 bits (66), Expect = 8.8
Identities = 30/111 (27%), Positives = 42/111 (37%), Gaps = 9/111 (8%)
Query: 517 APSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA---EGALKLGEEQQRQQWMANQ 573
AP+A G PP PS A ++ +A E +A G +K Q+ +
Sbjct: 6 APAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGP 65
Query: 574 SEALKLTM-----SAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQN 619
+ L + S GG G +GG P P L +SN P A N
Sbjct: 66 PQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDL-KNSNGNAGPRPALNN 115
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 66.2 bits (160), Expect = 1e-10
Identities = 79/297 (26%), Positives = 114/297 (38%), Gaps = 48/297 (16%)
Query: 69 SPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQL 128
+P PPPP +K +E A AAAAAAA + + Q+ +
Sbjct: 15 NPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESE--------------- 59
Query: 129 NHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVE---QRSRFEYPPPPVSLGSSSH 185
G +P G E G A + E + S P P +++
Sbjct: 60 GPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPAL---NNN 116
Query: 186 TARLPNGLGGPN----GFPK-------PTPEEGPPELNRQSPNSSSAAASVASRRGTHGG 234
P G GG + G P P P G + +SP++ +AAA+ + HGG
Sbjct: 117 LTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQ-QHGG 175
Query: 235 L----VTGLPNPGGGG-----GPQLTVPPNLLPQTLLNG--PASAAVLPPPPPHALGSRG 283
+ L + GGGG GPQ + P N P +A PP P +AL S
Sbjct: 176 QQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS-- 233
Query: 284 PPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQ 340
P PG+ G A G P S+++S++SSS+S + G GG + T Q
Sbjct: 234 -PRGGTPGS-GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQ 288
Score = 58.9 bits (141), Expect = 2e-08
Identities = 165/752 (21%), Positives = 238/752 (31%), Gaps = 168/752 (22%)
Query: 56 QLKRAHGCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQ 115
++K A G +G + GPP P+G + + A + + +
Sbjct: 49 EMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSNGNAG 108
Query: 116 QQQQQQQQQQQQLNHVDGSSKPAVLAAPSGL------------ERYGLSAAAAAAAAAAA 163
+ + G S V A P + YG S +A AAAAAA
Sbjct: 109 PRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSPSAVAAAAAAV 168
Query: 164 AVEQRSRFEYP-------------PPPVSLGSSSHTARLPNGLGG---PN--GFPKP--- 202
+Q + P P +SH PN PN +P P
Sbjct: 169 FHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPA 228
Query: 203 ----TPEEGPP------ELNRQSPNSSSAAASVAS------RRGTHGGLVTGLPNPGGGG 246
+P G P + P SSSA+AS +S R G GG G P+ GGG
Sbjct: 229 YALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG---GGPSAAGGG 285
Query: 247 GPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVS 306
PQ T P L LL P+SA P G P GA GPA + +
Sbjct: 286 TPQPTATPTL--NQLLTSPSSARGYQGYP----GGDYSGGPQDGGAGKGPADMASQCWGA 339
Query: 307 ATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAE 366
A +++A+++ S + A PGS Q R + + + + + R +
Sbjct: 340 AAAAAAAAAASGGAQQRSHHA-PMSPGSSGGGGQ-----PLARTPQPSSPMDQMGKMRPQ 393
Query: 367 EWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVFAFDAVSKPGMDYELKLFIEYP-T 425
+ G PY + PG Y + YP T
Sbjct: 394 PY--------------GGTNPYSQQQGPPSG------PQQGHGYPGQPYGSQTPQRYPMT 433
Query: 426 GSGNVYSSASGVAKQMYQDCMKDFGRGLSSGF------KYLEYEKKHGSGDWRLLGDLLP 479
G S+ G++ Y + +G+ SG+ Y + H P
Sbjct: 434 MQGRAQSAMGGLS---YTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPP 490
Query: 480 EAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPP-------------GTGA 526
P A Q + P L ++ S+ PS PP T
Sbjct: 491 SQ-------TPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543
Query: 527 LPPAAPSGRGAAASLRKRKASPEPPD----SAEGALKLGEEQQRQQWMANQ--------- 573
P + P A ++ P+ P S + A + QQ QQ +Q
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603
Query: 574 ---------SEALKLTMSAGGFAAPGHAAGGPPPPPPPL-GPHSNRTTPPESAPQNGPSP 623
S A +T S GG + P P L G + E A G S
Sbjct: 604 SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663
Query: 624 MAALMSVADTLGTAHSP-KDGSSVH------------STTASARRNSSSPVSPASVPGQR 670
S + A SP +S H + AS ++ S P+SPA+VPG
Sbjct: 664 SGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN- 722
Query: 671 RLASRNGDLNLQVAPPPPSA------HPGMDQ 696
Q+ P PPS HP M+Q
Sbjct: 723 -----------QMPPRPPSGQSDSIMHPSMNQ 743
Score = 30.0 bits (66), Expect = 8.8
Identities = 30/111 (27%), Positives = 42/111 (37%), Gaps = 9/111 (8%)
Query: 517 APSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSA---EGALKLGEEQQRQQWMANQ 573
AP+A G PP PS A ++ +A E +A G +K Q+ +
Sbjct: 6 APAAASSLGNPPPPPPSELKKAEQQQREEAGGEAAAAAAAERGEMKAAAGQESEGPAVGP 65
Query: 574 SEALKLTM-----SAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQN 619
+ L + S GG G +GG P P L +SN P A N
Sbjct: 66 PQPLGKELQDGAESNGGGGGGGAGSGGGPGAEPDL-KNSNGNAGPRPALNN 115
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 64.3 bits (155), Expect = 4e-10
Identities = 84/313 (26%), Positives = 107/313 (34%), Gaps = 91/313 (29%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNH-------------------------------- 130
QQQQQQQQQQQQQQQQQQQQQQQQQL
Sbjct: 261 QQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQ 320
Query: 131 -VDGSSKP-------AVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLG- 181
G+ +P + A G ++ L A ++ +PPPP G
Sbjct: 321 LPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGS 380
Query: 182 ---SSSHT-------------ARLPNGLGGPNGFPKP---------TPEEGPPELNRQSP 216
S +HT ++ + GGP+ P P +P P + SP
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440
Query: 217 NSSSAAASVASRRG----THGGLVTGLPNPGGGGG-----PQLTVPPNLL---PQTLLNG 264
SS + G + L G P G Q VPPN + Q G
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500
Query: 265 PASAAVLPPPPPHALGSRGPPTPAPPGAPGGPA----CLGGTPGVSATSSSASSSTSSSV 320
P S L P G G P PPG G A G P +AT+ S +
Sbjct: 501 PQS---LHP------GLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQA 551
Query: 321 AEVGVGAGGKRPG 333
+ AGG+ G
Sbjct: 552 NQNVQHAGGQGAG 564
Score = 42.0 bits (97), Expect = 0.002
Identities = 60/229 (26%), Positives = 84/229 (36%), Gaps = 34/229 (14%)
Query: 103 QQQQQQQQQQQQQ-------QQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAA 155
QQQ Q Q QQQQ Q QQQQQQQQQ + + P + P +S
Sbjct: 1002 QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLP-------VSQNV 1054
Query: 156 AAAAAAAAAVEQRSRFEYP---PPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELN 212
QR + P VSL + P+ P P +
Sbjct: 1055 HPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVY 1114
Query: 213 RQSPN--SSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAV 270
++SP SSS A +AS LP G P + PN +P ++ P + +
Sbjct: 1115 QESPQNPSSSPLAEMAS-----------LPEASGSEAPSVPGGPNNMPSHVVL-PQNQLM 1162
Query: 271 L--PPPPPHALGSRGPPTPAPPGAPGGPACLG-GTPGVSATSSSASSST 316
+ P P P L + TP P P+ G P V+A + ++ T
Sbjct: 1163 MTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKT 1211
Score = 35.0 bits (79), Expect = 0.27
Identities = 47/206 (22%), Positives = 64/206 (31%), Gaps = 33/206 (16%)
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PPG LP A P P + G + + ++ + L+
Sbjct: 315 PPGWNQLPSGA--------------LQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQAR 360
Query: 581 MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSP 640
S P H PPPP P G + P A + G + P
Sbjct: 361 PSLATVQTPSH-----PPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 415
Query: 641 KDGSSVHSTTASARRNSSS--PVSPASVPGQRRLASRNGDLNLQVAPPP-----PSAHPG 693
H T S + SS SPAS P + + G Q P P P + PG
Sbjct: 416 TPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 475
Query: 694 MD-QVHPQNIPDSPMA------NSGP 712
+ V N+P + M N GP
Sbjct: 476 RNPMVQQGNVPPNFMVMQQQPPNQGP 501
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 61.2 bits (147), Expect = 4e-09
Identities = 44/137 (32%), Positives = 57/137 (41%), Gaps = 15/137 (10%)
Query: 196 PNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGP-QLTVPP 254
P G P PT + PP Q P++ A + L L PGG G + PP
Sbjct: 476 PGGLPVPTYLQPPP----QPPSALGCALGESPALLRQAFL--DLAEPGGAAGSAEAAPPP 529
Query: 255 NLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASS 314
PQ + NGP S PPPP GSR +PPG GG G TP + +++ +
Sbjct: 530 GQPPQVVANGPGSG---PPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586
Query: 315 STSSSVAEVGVGAGGKR 331
+ A G G G R
Sbjct: 587 A-----AAAGSGPAGSR 598
Score = 35.8 bits (81), Expect = 0.16
Identities = 43/169 (25%), Positives = 56/169 (33%), Gaps = 34/169 (20%)
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PP PP P G L+ P+PP + AL RQ ++
Sbjct: 465 PPFCMFWPPRTPGGLPVPTYLQP---PPQPPSALGCALGESPALLRQAFL---------- 511
Query: 581 MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPE---SAPQNGPSPMAALMSVADTLGTA 637
A PG AAG PPP PP+ + P +GP P A D L
Sbjct: 512 ----DLAEPGGAAGSAEAAPPP-------GQPPQVVANGPGSGPPPPAGGAGSRDAL--F 558
Query: 638 HSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPP 686
SP GS S+ P + G A+ +G +V P
Sbjct: 559 ESPPGGSG-----GDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602
Score = 35.4 bits (80), Expect = 0.21
Identities = 85/354 (24%), Positives = 108/354 (30%), Gaps = 89/354 (25%)
Query: 72 PPPPVGVKTVALSAKEAAAAAAAAAAAA----------AAAQQQQQQQQQQQQQQQQQQQ 121
P P LS+ +AAA AAAAA A A +
Sbjct: 245 PQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHA 304
Query: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAA----------------------- 158
++ + + D S + A + A + L S + AAA
Sbjct: 305 HHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGA 364
Query: 159 -AAAAAAVEQRSRFEYPPPPV-SLGSSSHTARLPNGLGG----PNGFPKPT-------PE 205
A A A + YP PV S GS + G GG P FP +
Sbjct: 365 GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK 424
Query: 206 EGPPELNRQSPNSSSAAASVASRRG-------------------------THGGL----- 235
E + + A A + G T GGL
Sbjct: 425 EDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTY 484
Query: 236 VTGLPNPGGGGGPQLTVPPNLLPQTLLN--------GPASAAVLPPPPPHALGS---RGP 284
+ P P G L P LL Q L+ G A AA P PP + + GP
Sbjct: 485 LQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGP 544
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSS-TSSSVAEVGVGAGGKRPGSVSS 337
P PA GA A PG S SA S+ + SVA G GA G S
Sbjct: 545 PPPA-GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGS 597
Score = 35.0 bits (79), Expect = 0.27
Identities = 57/222 (25%), Positives = 73/222 (32%), Gaps = 40/222 (18%)
Query: 132 DGSSKPAVLAAPSGLER-YGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLP 190
+G S+ L P + LS+ AAA AAAAAV LG P
Sbjct: 236 NGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGL--------LG--------P 279
Query: 191 NGLGGPNGFPKPTPE----EGPPELNRQSPN-----------------SSSAAASVASRR 229
+ LG P P P P G P + + P S SAAA+ S
Sbjct: 280 HLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVA 339
Query: 230 GTHGGLVTGLPNPGGG--GGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTP 287
GG TG GGG G + GP S V+P P + G P
Sbjct: 340 AASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFP 399
Query: 288 APPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGG 329
G P + + +++ A G GAGG
Sbjct: 400 GCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGG 441
Score = 32.0 bits (71), Expect = 2.3
Identities = 24/88 (27%), Positives = 33/88 (37%), Gaps = 13/88 (14%)
Query: 265 PASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVG 324
P+ +LPP P R P P PP P P L P S +S S
Sbjct: 673 PSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCS------- 725
Query: 325 VGAGGKRPGSVSSTDQERELKEKQRNAE 352
P SS D++ E +E++ + E
Sbjct: 726 ------YPSEDSSEDEDDEEEEQEVDVE 747
Score = 31.6 bits (70), Expect = 3.0
Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 584 GGFAAPGHAAGGPPPPPPPLGPHSNRTTPPES 615
GG P H G PPPPPPP P + P +
Sbjct: 274 GGLLGP-HLLGAPPPPPPPPPPLAELAGAPHA 304
Score = 30.0 bits (66), Expect = 8.8
Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 43/149 (28%)
Query: 520 APPG-------TGALPPA---APSGRGAAAS----LRKRKASPEPPDSAEGALKLGEEQQ 565
+PPG G+ PPA A +G GAAA+ R +P P EG G
Sbjct: 560 SPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYH 619
Query: 566 RQQW---MANQSEALKLTMSAGGFAAPGHAAGG----------------PPPPPPPL--- 603
+ + +A L G A H+A PP PP PL
Sbjct: 620 HSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLL 679
Query: 604 -------GPHSNRTTPPESAPQNGPSPMA 625
G + PP P P P+A
Sbjct: 680 PPQPDEPGSERHHPAPPPPPPPPPPPPLA 708
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 61.2 bits (147), Expect = 4e-09
Identities = 44/137 (32%), Positives = 57/137 (41%), Gaps = 15/137 (10%)
Query: 196 PNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGP-QLTVPP 254
P G P PT + PP Q P++ A + L L PGG G + PP
Sbjct: 476 PGGLPVPTYLQPPP----QPPSALGCALGESPALLRQAFL--DLAEPGGAAGSAEAAPPP 529
Query: 255 NLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASS 314
PQ + NGP S PPPP GSR +PPG GG G TP + +++ +
Sbjct: 530 GQPPQVVANGPGSG---PPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586
Query: 315 STSSSVAEVGVGAGGKR 331
+ A G G G R
Sbjct: 587 A-----AAAGSGPAGSR 598
Score = 35.8 bits (81), Expect = 0.16
Identities = 43/169 (25%), Positives = 56/169 (33%), Gaps = 34/169 (20%)
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PP PP P G L+ P+PP + AL RQ ++
Sbjct: 465 PPFCMFWPPRTPGGLPVPTYLQP---PPQPPSALGCALGESPALLRQAFL---------- 511
Query: 581 MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPE---SAPQNGPSPMAALMSVADTLGTA 637
A PG AAG PPP PP+ + P +GP P A D L
Sbjct: 512 ----DLAEPGGAAGSAEAAPPP-------GQPPQVVANGPGSGPPPPAGGAGSRDAL--F 558
Query: 638 HSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPP 686
SP GS S+ P + G A+ +G +V P
Sbjct: 559 ESPPGGSG-----GDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602
Score = 35.4 bits (80), Expect = 0.21
Identities = 85/354 (24%), Positives = 108/354 (30%), Gaps = 89/354 (25%)
Query: 72 PPPPVGVKTVALSAKEAAAAAAAAAAAA----------AAAQQQQQQQQQQQQQQQQQQQ 121
P P LS+ +AAA AAAAA A A +
Sbjct: 245 PQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHA 304
Query: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAA----------------------- 158
++ + + D S + A + A + L S + AAA
Sbjct: 305 HHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGA 364
Query: 159 -AAAAAAVEQRSRFEYPPPPV-SLGSSSHTARLPNGLGG----PNGFPKPT-------PE 205
A A A + YP PV S GS + G GG P FP +
Sbjct: 365 GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK 424
Query: 206 EGPPELNRQSPNSSSAAASVASRRG-------------------------THGGL----- 235
E + + A A + G T GGL
Sbjct: 425 EDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTY 484
Query: 236 VTGLPNPGGGGGPQLTVPPNLLPQTLLN--------GPASAAVLPPPPPHALGS---RGP 284
+ P P G L P LL Q L+ G A AA P PP + + GP
Sbjct: 485 LQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGP 544
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSS-TSSSVAEVGVGAGGKRPGSVSS 337
P PA GA A PG S SA S+ + SVA G GA G S
Sbjct: 545 PPPA-GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGS 597
Score = 35.0 bits (79), Expect = 0.27
Identities = 57/222 (25%), Positives = 73/222 (32%), Gaps = 40/222 (18%)
Query: 132 DGSSKPAVLAAPSGLER-YGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLP 190
+G S+ L P + LS+ AAA AAAAAV LG P
Sbjct: 236 NGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGL--------LG--------P 279
Query: 191 NGLGGPNGFPKPTPE----EGPPELNRQSPN-----------------SSSAAASVASRR 229
+ LG P P P P G P + + P S SAAA+ S
Sbjct: 280 HLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVA 339
Query: 230 GTHGGLVTGLPNPGGG--GGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTP 287
GG TG GGG G + GP S V+P P + G P
Sbjct: 340 AASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFP 399
Query: 288 APPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGG 329
G P + + +++ A G GAGG
Sbjct: 400 GCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGG 441
Score = 31.6 bits (70), Expect = 3.0
Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 584 GGFAAPGHAAGGPPPPPPPLGPHSNRTTPPES 615
GG P H G PPPPPPP P + P +
Sbjct: 274 GGLLGP-HLLGAPPPPPPPPPPLAELAGAPHA 304
Score = 30.0 bits (66), Expect = 8.8
Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 43/149 (28%)
Query: 520 APPG-------TGALPPA---APSGRGAAAS----LRKRKASPEPPDSAEGALKLGEEQQ 565
+PPG G+ PPA A +G GAAA+ R +P P EG G
Sbjct: 560 SPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYH 619
Query: 566 RQQW---MANQSEALKLTMSAGGFAAPGHAAGG----------------PPPPPPPL--- 603
+ + +A L G A H+A PP PP PL
Sbjct: 620 HSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLL 679
Query: 604 -------GPHSNRTTPPESAPQNGPSPMA 625
G + PP P P P+A
Sbjct: 680 PPQPDEPGSERHHPAPPPPPPPPPPPPLA 708
Score = 30.0 bits (66), Expect = 8.8
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 13/88 (14%)
Query: 265 PASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVG 324
P+ +LPP P R P P PP P P L P S +S
Sbjct: 673 PSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCC------- 725
Query: 325 VGAGGKRPGSVSSTDQERELKEKQRNAE 352
P SS D++ E +E++ + E
Sbjct: 726 ------YPSEDSSEDEDDEEEEQEVDVE 747
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 61.2 bits (147), Expect = 4e-09
Identities = 44/137 (32%), Positives = 57/137 (41%), Gaps = 15/137 (10%)
Query: 196 PNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGP-QLTVPP 254
P G P PT + PP Q P++ A + L L PGG G + PP
Sbjct: 476 PGGLPVPTYLQPPP----QPPSALGCALGESPALLRQAFL--DLAEPGGAAGSAEAAPPP 529
Query: 255 NLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASS 314
PQ + NGP S PPPP GSR +PPG GG G TP + +++ +
Sbjct: 530 GQPPQVVANGPGSG---PPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586
Query: 315 STSSSVAEVGVGAGGKR 331
+ A G G G R
Sbjct: 587 A-----AAAGSGPAGSR 598
Score = 35.8 bits (81), Expect = 0.16
Identities = 43/169 (25%), Positives = 56/169 (33%), Gaps = 34/169 (20%)
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PP PP P G L+ P+PP + AL RQ ++
Sbjct: 465 PPFCMFWPPRTPGGLPVPTYLQP---PPQPPSALGCALGESPALLRQAFL---------- 511
Query: 581 MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPE---SAPQNGPSPMAALMSVADTLGTA 637
A PG AAG PPP PP+ + P +GP P A D L
Sbjct: 512 ----DLAEPGGAAGSAEAAPPP-------GQPPQVVANGPGSGPPPPAGGAGSRDAL--F 558
Query: 638 HSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPP 686
SP GS S+ P + G A+ +G +V P
Sbjct: 559 ESPPGGSG-----GDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP 602
Score = 35.4 bits (80), Expect = 0.21
Identities = 85/354 (24%), Positives = 108/354 (30%), Gaps = 89/354 (25%)
Query: 72 PPPPVGVKTVALSAKEAAAAAAAAAAAA----------AAAQQQQQQQQQQQQQQQQQQQ 121
P P LS+ +AAA AAAAA A A +
Sbjct: 245 PQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHA 304
Query: 122 QQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAA----------------------- 158
++ + + D S + A + A + L S + AAA
Sbjct: 305 HHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGA 364
Query: 159 -AAAAAAVEQRSRFEYPPPPV-SLGSSSHTARLPNGLGG----PNGFPKPT-------PE 205
A A A + YP PV S GS + G GG P FP +
Sbjct: 365 GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK 424
Query: 206 EGPPELNRQSPNSSSAAASVASRRG-------------------------THGGL----- 235
E + + A A + G T GGL
Sbjct: 425 EDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTY 484
Query: 236 VTGLPNPGGGGGPQLTVPPNLLPQTLLN--------GPASAAVLPPPPPHALGS---RGP 284
+ P P G L P LL Q L+ G A AA P PP + + GP
Sbjct: 485 LQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGP 544
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSS-TSSSVAEVGVGAGGKRPGSVSS 337
P PA GA A PG S SA S+ + SVA G GA G S
Sbjct: 545 PPPA-GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGS 597
Score = 35.0 bits (79), Expect = 0.27
Identities = 57/222 (25%), Positives = 73/222 (32%), Gaps = 40/222 (18%)
Query: 132 DGSSKPAVLAAPSGLER-YGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLP 190
+G S+ L P + LS+ AAA AAAAAV LG P
Sbjct: 236 NGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGL--------LG--------P 279
Query: 191 NGLGGPNGFPKPTPE----EGPPELNRQSPN-----------------SSSAAASVASRR 229
+ LG P P P P G P + + P S SAAA+ S
Sbjct: 280 HLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVA 339
Query: 230 GTHGGLVTGLPNPGGG--GGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTP 287
GG TG GGG G + GP S V+P P + G P
Sbjct: 340 AASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFP 399
Query: 288 APPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGG 329
G P + + +++ A G GAGG
Sbjct: 400 GCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGG 441
Score = 31.6 bits (70), Expect = 3.0
Identities = 14/32 (43%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 584 GGFAAPGHAAGGPPPPPPPLGPHSNRTTPPES 615
GG P H G PPPPPPP P + P +
Sbjct: 274 GGLLGP-HLLGAPPPPPPPPPPLAELAGAPHA 304
Score = 30.0 bits (66), Expect = 8.8
Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 43/149 (28%)
Query: 520 APPG-------TGALPPA---APSGRGAAAS----LRKRKASPEPPDSAEGALKLGEEQQ 565
+PPG G+ PPA A +G GAAA+ R +P P EG G
Sbjct: 560 SPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYH 619
Query: 566 RQQW---MANQSEALKLTMSAGGFAAPGHAAGG----------------PPPPPPPL--- 603
+ + +A L G A H+A PP PP PL
Sbjct: 620 HSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLL 679
Query: 604 -------GPHSNRTTPPESAPQNGPSPMA 625
G + PP P P P+A
Sbjct: 680 PPQPDEPGSERHHPAPPPPPPPPPPPPLA 708
Score = 30.0 bits (66), Expect = 8.8
Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 13/88 (14%)
Query: 265 PASAAVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVG 324
P+ +LPP P R P P PP P P L P S +S
Sbjct: 673 PSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCC------- 725
Query: 325 VGAGGKRPGSVSSTDQERELKEKQRNAE 352
P SS D++ E +E++ + E
Sbjct: 726 ------YPSEDSSEDEDDEEEEQEVDVE 747
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 60.8 bits (146), Expect = 5e-09
Identities = 74/256 (28%), Positives = 86/256 (33%), Gaps = 37/256 (14%)
Query: 62 GCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQ-- 119
G D RSP PP +G+ + QQQQQ QQ QQ
Sbjct: 26 GGLHDFRSP--PPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPP 83
Query: 120 --------QQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRF 171
Q QQQQ SSKP V P G+ +A A+++A A S
Sbjct: 84 PHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAP--GVGSAPPASSSAPPATPPTS-- 139
Query: 172 EYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEE-----------GPPELNRQSPNSSS 220
PP S G P P G P PTP GPP P
Sbjct: 140 --GAPPGS-GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
Query: 221 AAASVASRRGTHGGLVTGLPNPGGGGGPQLTVP-PNLLPQTLLNGPASAAVLPPPPPHAL 279
G GG + G P P GGGP L+ P + P G PP H
Sbjct: 197 GPKQGPGPGGPKGGKMPGGPKP--GGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQ 254
Query: 280 GSRGPPTPAPPGAPGG 295
+GP PPG PGG
Sbjct: 255 HHQGP----PPGGPGG 266
Score = 45.1 bits (105), Expect = 3e-04
Identities = 41/160 (25%), Positives = 49/160 (30%), Gaps = 6/160 (3%)
Query: 174 PPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHG 233
PPPP + P P P P P+ P +Q P ++ +G
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ---PHQQQQPPPPPQDSSKPVVAQGPGP 117
Query: 234 GLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTPAPPGAP 293
G P P T P + P +GP PP A PPTP G P
Sbjct: 118 APGVGSAPPASSSAPPATPPTSGAPPG--SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVP 175
Query: 294 GGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPG 333
P GG P A G GGK PG
Sbjct: 176 TTPPQAGGPPPPPAAVPGPGPGPKQGPGP-GGPKGGKMPG 214
Score = 41.6 bits (96), Expect = 0.003
Identities = 55/214 (25%), Positives = 67/214 (31%), Gaps = 44/214 (20%)
Query: 519 SAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEE--------------- 563
S PPG G P G G S K P PP + +
Sbjct: 33 SPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQ 92
Query: 564 -QQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPP----PPPLGPHSNRTTPPESAPQ 618
Q+QQ ++ K ++ G APG G PP PP P S PP S P
Sbjct: 93 PHQQQQPPPPPQDSSKPVVAQGPGPAPG--VGSAPPASSSAPPATPPTSG--APPGSGPG 148
Query: 619 NGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGD 678
P+P A+ S G S V +T A P PA+VPG
Sbjct: 149 PTPTPPPAVTSAPP--GAPPPTPPSSGVPTTPPQA---GGPPPPPAAVPG---------- 193
Query: 679 LNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGP 712
P P PG +P P GP
Sbjct: 194 -----PGPGPKQGPGPGGPKGGKMPGGPKPGGGP 222
Score = 41.2 bits (95), Expect = 0.004
Identities = 35/128 (27%), Positives = 45/128 (35%), Gaps = 23/128 (17%)
Query: 496 PQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAE 555
P P D+S P++ SAPP + + PPA P GA +P PP +
Sbjct: 100 PPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPG-SGPGPTPTPPPAVT 158
Query: 556 GALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPES 615
A A T + G AGGPPPPP + P
Sbjct: 159 SA---------------PPGAPPPTPPSSGVPTTPPQAGGPPPPPAAV-------PGPGP 196
Query: 616 APQNGPSP 623
P+ GP P
Sbjct: 197 GPKQGPGP 204
Score = 34.7 bits (78), Expect = 0.36
Identities = 36/133 (27%), Positives = 45/133 (33%), Gaps = 32/133 (24%)
Query: 490 PGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGA--LPPAAPSGRGAAASLRKRKAS 547
PG P P + ++ P P S P+ PP G PPAA G G K
Sbjct: 147 PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP-----KQG 201
Query: 548 PEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPP-------PP- 599
P P G + G + ++ + GG P H GG P PP
Sbjct: 202 PGPGGPKGGKMPGGPKPGGGPGLS----------TPGGHPKPPHRGGGEPRGGRQHHPPY 251
Query: 600 -------PPPLGP 605
PPP GP
Sbjct: 252 HQQHHQGPPPGGP 264
Score = 33.9 bits (76), Expect = 0.61
Identities = 25/77 (32%), Positives = 28/77 (36%), Gaps = 15/77 (19%)
Query: 229 RGTHGGLVTGLPNPGGGGGP----QLTVPPNLLPQTLLNGPASAAV--------LPPPPP 276
RG GG G GGGGG PP + GP +PPPPP
Sbjct: 9 RGGGGG---GFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPP 65
Query: 277 HALGSRGPPTPAPPGAP 293
H + PP PP P
Sbjct: 66 HQQQQQPPPQQPPPQQP 82
>gi|226442791 runt-related transcription factor 2 isoform b [Homo
sapiens]
Length = 499
Score = 60.5 bits (145), Expect = 6e-09
Identities = 39/65 (60%), Positives = 40/65 (61%), Gaps = 21/65 (32%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAA 160
AAQQQQQQQQQQQQQQQQQQQQQQQ E +AAAAAAAA
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQ---------------------EAAAAAAAAAAAAA 85
Query: 161 AAAAV 165
AAAAV
Sbjct: 86 AAAAV 90
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 538 AASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPP 597
++SL+ K S P A + ++QQ+QQ Q + + +A AA AA
Sbjct: 31 SSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAV 90
Query: 598 PPPPPLGPHSNRT 610
P P PH NRT
Sbjct: 91 PRLRP--PHDNRT 101
>gi|226442783 runt-related transcription factor 2 isoform a [Homo
sapiens]
Length = 521
Score = 60.5 bits (145), Expect = 6e-09
Identities = 39/65 (60%), Positives = 40/65 (61%), Gaps = 21/65 (32%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAA 160
AAQQQQQQQQQQQQQQQQQQQQQQQ E +AAAAAAAA
Sbjct: 47 AAQQQQQQQQQQQQQQQQQQQQQQQ---------------------EAAAAAAAAAAAAA 85
Query: 161 AAAAV 165
AAAAV
Sbjct: 86 AAAAV 90
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 538 AASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPP 597
++SL+ K S P A + ++QQ+QQ Q + + +A AA AA
Sbjct: 31 SSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAV 90
Query: 598 PPPPPLGPHSNRT 610
P P PH NRT
Sbjct: 91 PRLRP--PHDNRT 101
>gi|66934969 runt-related transcription factor 2 isoform c [Homo
sapiens]
Length = 507
Score = 60.5 bits (145), Expect = 6e-09
Identities = 39/65 (60%), Positives = 40/65 (61%), Gaps = 21/65 (32%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAA 160
AAQQQQQQQQQQQQQQQQQQQQQQQ E +AAAAAAAA
Sbjct: 33 AAQQQQQQQQQQQQQQQQQQQQQQQ---------------------EAAAAAAAAAAAAA 71
Query: 161 AAAAV 165
AAAAV
Sbjct: 72 AAAAV 76
Score = 31.6 bits (70), Expect = 3.0
Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 2/73 (2%)
Query: 538 AASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPP 597
++SL+ K S P A + ++QQ+QQ Q + + +A AA AA
Sbjct: 17 SSSLQPGKMSDVSPVVAAQQQQQQQQQQQQQQQQQQQQQQQEAAAAAAAAAAAAAAAAAV 76
Query: 598 PPPPPLGPHSNRT 610
P P PH NRT
Sbjct: 77 PRLRP--PHDNRT 87
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 60.5 bits (145), Expect = 6e-09
Identities = 64/211 (30%), Positives = 81/211 (38%), Gaps = 34/211 (16%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAA 162
QQQQQQQQQQQQQQQQQQQQQQQQQ +S+ V + A
Sbjct: 2720 QQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEH 2779
Query: 163 AAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPE-----EGPPELNRQSPN 217
Q+ + + PP P P P P+PT + PP+ +QSP
Sbjct: 2780 LIKMQKQKLQMPPQPPP----------PQAQSAP---PQPTAQVQVQTSQPPQ--QQSPQ 2824
Query: 218 SSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLP-----QTLLNGPASAAVLP 272
++ A G L+TG VP + L QT PA A+
Sbjct: 2825 LTTVTAP------RPGALLTGTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK 2878
Query: 273 PP---PPHALGSRGPPTPAPPGAPGGPACLG 300
PP P A+ S T P G +G
Sbjct: 2879 PPVVSVPAAVVSSPGVTTLPMNVAGISVAIG 2909
Score = 37.7 bits (86), Expect = 0.042
Identities = 45/166 (27%), Positives = 65/166 (39%), Gaps = 25/166 (15%)
Query: 70 PGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLN 129
PG PP GV T ALS +A QQ Q + Q Q Q + QQ +
Sbjct: 557 PGRLPPAGVPTAALS-------------SALQFAQQPQVVEAQTQLQIPVKTQQPNVPIP 603
Query: 130 HVDGSSKPAVLAAPSGLERY----GLSAAAAAAAAAAAAVEQRSRFEY---PPPPVSLGS 182
S P + P+ L + G A+ ++ + +R PP P L +
Sbjct: 604 APPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPT 663
Query: 183 SSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASR 228
SS ++ P GP P+P P +NR S ++ A + V SR
Sbjct: 664 SSTSSLAPVSGSGPG----PSPARSSP-VNRPSSATNKALSPVTSR 704
Score = 37.7 bits (86), Expect = 0.042
Identities = 66/250 (26%), Positives = 89/250 (35%), Gaps = 45/250 (18%)
Query: 74 PPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQ---------------QQQQQQQQQQQQQ 118
PP+ + AK AAA + A+A+A + Q + + Q Q
Sbjct: 1469 PPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTP 1528
Query: 119 QQQQQQQQQLNHVDG-SSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPP 177
Q Q Q +H G S+ P L PS + S A A+ +SR P P
Sbjct: 1529 GQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETP 1588
Query: 178 VSL---GSS---SHTARLPNGLGGP----NGFPKPTPEEGPPELNRQSPNSSSAAASVAS 227
V+L GS SH+ G P + G P L P +V+
Sbjct: 1589 VTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGP---VVMQTVSQ 1645
Query: 228 RRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPPTP 287
HG L + P GGP P L PQ + P AV +AL P T
Sbjct: 1646 AGAVHGALGSKPP----AGGPS---PAPLTPQ--VGVPGRVAV------NALAVGEPGTA 1690
Query: 288 APPGAP-GGP 296
+ P +P GGP
Sbjct: 1691 SKPASPIGGP 1700
Score = 35.4 bits (80), Expect = 0.21
Identities = 56/243 (23%), Positives = 92/243 (37%), Gaps = 45/243 (18%)
Query: 172 EYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAA----ASVAS 227
+ PPPP+ ++ + + P G P+P P+ P + Q+P + A S A
Sbjct: 2518 QQPPPPLPQPQAAGS-QPPAGPPAVQPQPQPQPQTQPQPV--QAPAKAQPAITTGGSAAV 2574
Query: 228 RRGTHGGLVTGLPNPGGG-----------GGPQLT-----------VPPNLLPQTLLNGP 265
GT VTG P G G P T V P L T G
Sbjct: 2575 LAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGAL--TTPGGS 2632
Query: 266 ASAAVL-PPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTS------- 317
A A V+ PPP A+GS TP A G V++ ++SA +T+
Sbjct: 2633 APAQVVHTQPPPRAVGSPATATPDLVSM----ATTQGVRAVTSVTASAVVTTNLTPVQTP 2688
Query: 318 --SSVAEVGVGAGGKRPGSVSSTDQERELKEKQRNAEALAELSESLRNRAEEWASKPKMV 375
S V +V G + PG + + L+++Q+ + + + + + ++ + +
Sbjct: 2689 ARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQT 2748
Query: 376 RDT 378
T
Sbjct: 2749 TTT 2751
Score = 33.9 bits (76), Expect = 0.61
Identities = 54/242 (22%), Positives = 82/242 (33%), Gaps = 26/242 (10%)
Query: 98 AAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAA 157
A A +Q +++++++++++++ + +N + V A S +E A
Sbjct: 412 APLQAYLRQNDLDIEEEEEEEEEEEEKSEVINDEQALAGSLVAGAGSTVETDLFKRQQAM 471
Query: 158 AAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPN---GFPKPTPEEGPPELNRQ 214
+ A +R R E V A +P P G P PTP+ RQ
Sbjct: 472 PSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMP-PTPQAAQLAGQRQ 530
Query: 215 SPNS--SSAAASVASRRGTHGGLV--------TGLPNPGGGGGPQLTVPPNLLP-QTLLN 263
S S V + H L G+P Q P ++ QT L
Sbjct: 531 SQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQ 590
Query: 264 GPASA----AVLPPPPPHALGSRGPPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSS 319
P +P PP L P PP P A TPG +S SS
Sbjct: 591 IPVKTQQPNVPIPAPPSSQL-------PIPPSQPAQLALHVPTPGKVQVQASQLSSLPQM 643
Query: 320 VA 321
VA
Sbjct: 644 VA 645
Score = 31.6 bits (70), Expect = 3.0
Identities = 41/146 (28%), Positives = 50/146 (34%), Gaps = 25/146 (17%)
Query: 70 PGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLN 129
P PPPP L +AA + A A Q Q Q Q Q Q Q Q + Q
Sbjct: 2511 PQPPPPPQQPPPPLPQPQAAGSQPPAGPPAV----QPQPQPQPQTQPQPVQAPAKAQPAI 2566
Query: 130 HVDGSSKPAVLAA-----------PSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPV 178
GS+ AVLA P+G + A AA R P P
Sbjct: 2567 TTGGSA--AVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPG 2624
Query: 179 SL---GSSS-----HTARLPNGLGGP 196
+L G S+ HT P +G P
Sbjct: 2625 ALTTPGGSAPAQVVHTQPPPRAVGSP 2650
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/253 (27%), Positives = 88/253 (34%), Gaps = 38/253 (15%)
Query: 133 GSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNG 192
G + PA P G A AAAA AA E P P + A L
Sbjct: 118 GPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--------PAPAGPAKPAGPAALAAR 169
Query: 193 LG-GPNGFPKPTPEEGPPE---------LNRQSP--NSSSAAASVASRRGTHGGLVTGLP 240
G GP P P P GP + LN + NS AAA S + LP
Sbjct: 170 AGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLP 229
Query: 241 NPGGGGGPQLTVP---------PNLLPQTLLNGPASAAVLPPPPPHALGS--------RG 283
P G T P P PA+ A PPPPP A + G
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289
Query: 284 PPTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPG-SVSSTDQER 342
PPT AP P A GG+ G + + A+ + + G GA P V + +R
Sbjct: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349
Query: 343 ELKEKQRNAEALA 355
++ A+ LA
Sbjct: 350 VVQAAPPAAQTLA 362
Score = 55.8 bits (133), Expect = 1e-07
Identities = 75/268 (27%), Positives = 98/268 (36%), Gaps = 39/268 (14%)
Query: 67 GRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQ 126
G PGP P G A +AA + AAA A +
Sbjct: 181 GPGPGPGKPAGPG--AAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVI 238
Query: 127 QLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHT 186
Q G++ P AAPS AA A AA AAA PPPP +
Sbjct: 239 QTPPFVGAAAPPAPAAPSP------PAAPAPAAPAAAP---------PPPPPA------P 277
Query: 187 ARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGG 246
A L G P G P P PP + ++ +A A + G G V+G P PG
Sbjct: 278 ATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAG--VSGQPGPGAAA 335
Query: 247 -----GPQLTVPPNLLP------QTLL-NGPASAAVLPPPPPHALGSRGPPTPAPPGAPG 294
G + P ++ QTL +GPAS A P G+ P PP APG
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Query: 295 GPACL--GGTPGVSATSSSASSSTSSSV 320
P L G V+ + S ++T+S +
Sbjct: 396 TPTGLPKGAAGAVTQSLSRTPTATTSGI 423
Score = 48.1 bits (113), Expect = 3e-05
Identities = 38/107 (35%), Positives = 43/107 (40%), Gaps = 18/107 (16%)
Query: 215 SPNSSSAAASVASRRGTHGGLV----TGLPNPGGGGGPQLTVPPNLLPQTLLNGPA-SAA 269
SP ++ A A G G G PG GGGPQ PP+ + GPA AA
Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPG-GGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 270 VLPPPPPHALGSRGP------------PTPAPPGAPGGPACLGGTPG 304
L PPP + GS P P PA P P GPA L G
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAG 171
Score = 45.8 bits (107), Expect = 2e-04
Identities = 57/221 (25%), Positives = 79/221 (35%), Gaps = 27/221 (12%)
Query: 505 PMLPTALVSLSR-APSAPPGTGALP-PAAPSGRGAAASLRKRKASPEPPDSAEGALKLGE 562
P P AL + + P PG G P P P+G GAA +L A +A A+ L
Sbjct: 160 PAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL-- 217
Query: 563 EQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPP-----PPPPPLGPHSNRTTPPESAP 617
N A L + AAPG PP PP P P P +
Sbjct: 218 --------VNNGPAALLPLPKP--AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267
Query: 618 QNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNG 677
P P A ++A G P + A+A+ S+ +PA P A +G
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG 327
Query: 678 DLNLQVAPPPPSAHPGMDQVHPQNIPDS------PMANSGP 712
A P+ PG+ P+ + + +A SGP
Sbjct: 328 QPGPGAAAAAPA--PGVKAESPKRVVQAAPPAAQTLAASGP 366
Score = 42.7 bits (99), Expect = 0.001
Identities = 47/183 (25%), Positives = 65/183 (35%), Gaps = 23/183 (12%)
Query: 486 KEGVPGADMLPQPYLDASCPMLPTA-LVSLSRAPSAPPGTGALPPAAPSGRGAAASLRKR 544
K PG + P++ A+ P P A + AP+AP PP AP A+L +
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAP------ATLARP 283
Query: 545 KASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLG 604
P P +A A+ A + SAG AP AAGGP G
Sbjct: 284 PGHPAGPPTAAPAVP-------------PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330
Query: 605 PHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPA 664
P + P SP + + T + S+ S + P SPA
Sbjct: 331 PGAAAAAPAPGV--KAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALP-SPA 387
Query: 665 SVP 667
+VP
Sbjct: 388 AVP 390
Score = 41.6 bits (96), Expect = 0.003
Identities = 38/121 (31%), Positives = 45/121 (37%), Gaps = 13/121 (10%)
Query: 582 SAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQ--NGPSPMAALMSV--ADTLGTA 637
+ G AAP A G P PPP G R P PQ PSP L+ A
Sbjct: 71 AGAGPAAPAEGAPGAAPEPPPAG----RARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
Query: 638 HSPKDGSS-----VHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHP 692
P +GS+ V + A A +P PA G LA+R G P P P
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
Query: 693 G 693
G
Sbjct: 187 G 187
Score = 38.9 bits (89), Expect = 0.019
Identities = 50/189 (26%), Positives = 64/189 (33%), Gaps = 28/189 (14%)
Query: 137 PAVLAAPSG-LERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGG 195
P V AA +G L + +S + A AA A A P P G R G GG
Sbjct: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAG------RARPGGGG 101
Query: 196 PNGFPKPTPEE-----GP-PELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQ 249
P P+P GP P + P +A S A P P G P
Sbjct: 102 PQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161
Query: 250 LTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGP-PTPAPPGAPGGPACLGGTPGVSAT 308
GPA+ A P P GP P P P PG L G+ + +
Sbjct: 162 --------------GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNS 207
Query: 309 SSSASSSTS 317
+A+ + S
Sbjct: 208 HHAAAPAVS 216
Score = 36.6 bits (83), Expect = 0.094
Identities = 33/118 (27%), Positives = 41/118 (34%), Gaps = 18/118 (15%)
Query: 215 SPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPP 274
+P + A+ A G H +V+G P G GP G AA PPP
Sbjct: 44 APRTPEVRAAAAGALGNH--VVSGSPAGAAGAGPAAPA----------EGAPGAAPEPPP 91
Query: 275 PPHAL-GSRGPPTPAPPG-----APGGPACLGGTPGVSATSSSASSSTSSSVAEVGVG 326
A G GP P PP P GPA S+ S + + A V G
Sbjct: 92 AGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG 149
Score = 36.6 bits (83), Expect = 0.094
Identities = 56/217 (25%), Positives = 81/217 (37%), Gaps = 33/217 (15%)
Query: 490 PGADMLPQPYLDASCPMLPT-ALVSLSRAPSAPPG----TGALPPAAPSGRGAAASLRKR 544
P P P A+ P P A +L+R P P G A+PP A + G +A
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAG---- 310
Query: 545 KASPEPPDSAEGALKLGEEQQRQQWMAN-----QSEALKLTMSAGGFAAPGHAAGGPPPP 599
A+P P +A G + + A ++E+ K + A AA AA GP
Sbjct: 311 -AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369
Query: 600 PPP--LGPHSNRTTP-PESAPQNGPS-----PMAALMSVADTLGTAHSPKDGSSVHST-- 649
+GP P P + P P P A +V +L + S + +T
Sbjct: 370 AASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT-SGIRATLT 428
Query: 650 -TASARRNSSSPVSPASV------PGQRRLASRNGDL 679
T A R P +P ++ PG + S NG L
Sbjct: 429 PTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQL 465
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 59.3 bits (142), Expect = 1e-08
Identities = 36/70 (51%), Positives = 42/70 (60%), Gaps = 2/70 (2%)
Query: 75 PVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGS 134
PV V + +S E AA A QQ+QQQQQQQQQQQQQQQQQQQQQ H + +
Sbjct: 454 PVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQ--HSNQT 511
Query: 135 SKPAVLAAPS 144
S + L PS
Sbjct: 512 SNWSPLGPPS 521
Score = 43.9 bits (102), Expect = 6e-04
Identities = 26/55 (47%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Query: 105 QQQQQQQQQQQQQQQQQQQQQQQLN----HVDGSSKPAVLAAPSGLERYGLSAAA 155
QQQQQQQQQQQQQQQQQQ QL H+ K +L G+ ++ AA
Sbjct: 629 QQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAA 683
Score = 37.7 bits (86), Expect = 0.042
Identities = 55/238 (23%), Positives = 86/238 (36%), Gaps = 21/238 (8%)
Query: 62 GCFQDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQ---Q 118
G G SP P +G + A K+ A Q ++Q+QQQQQQQQ +
Sbjct: 712 GGMVSGASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE 771
Query: 119 QQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPV 178
QQ QQ H+ P + + + AA + AA ++ +
Sbjct: 772 QQLQQSHLPRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMM 831
Query: 179 SLGSSSH-----TARLPNGLGGPNGFPKPTPEEGPPELNR------QSPNSSSAAASVAS 227
+G S + TA + +G PT + G ++ Q PN S + +
Sbjct: 832 GIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQ 891
Query: 228 RRGTH---GGLVTGLPNPGGGGGPQLTVPPNLLPQ-TLLNGPASAAVLPPPPPHALGS 281
+G G G+ + G G + V + Q + GP A+ P P L S
Sbjct: 892 AQGPRQPASGQGVGMVS---GFGQSMLVNSAITQQHPQMKGPVGQALPRPQAPPRLQS 946
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 58.5 bits (140), Expect = 2e-08
Identities = 31/42 (73%), Positives = 32/42 (76%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPS 144
QQQQQQQQQQQQQQQQQQQQQQQQQ S P V A+PS
Sbjct: 1250 QQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPS 1291
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAA 162
QQQQQQQQQQQQQQQQQQQQQQQQQ S P + A ++ GL A A
Sbjct: 1249 QQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMD--GLLAGPTMPQAPP 1306
Query: 163 AAVEQRSRF---EYPPPPVSLGSSSHTARLPNGLG 194
+ + + P P SS A + + +G
Sbjct: 1307 QQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMG 1341
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/58 (43%), Positives = 31/58 (53%)
Query: 70 PGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQ 127
P P V + L+A+ A + + Q+ QQQQQQQQQQQQQQQQQQ
Sbjct: 1208 PMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQ 1265
Score = 30.0 bits (66), Expect = 8.8
Identities = 34/171 (19%), Positives = 59/171 (34%), Gaps = 20/171 (11%)
Query: 562 EEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGP--------------PPPPPPLGPHS 607
++QQ+QQ Q + + F+ P + P PP P P+
Sbjct: 1256 QQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNY 1315
Query: 608 NRTTPPESAPQNGPSPMAALMSVADTLGTAHSP----KDGSSVHSTTASARRNSSSPVSP 663
P+ A SP A+MS +G + +P +S++ ++ S +
Sbjct: 1316 GMGQQPDPAFGRVSSPPNAMMS--SRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARN 1373
Query: 664 ASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLC 714
+S Q+ N + V S H G ++P + PM C
Sbjct: 1374 SSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1424
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 58.5 bits (140), Expect = 2e-08
Identities = 31/42 (73%), Positives = 32/42 (76%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPS 144
QQQQQQQQQQQQQQQQQQQQQQQQQ S P V A+PS
Sbjct: 1246 QQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPS 1287
Score = 57.8 bits (138), Expect = 4e-08
Identities = 38/95 (40%), Positives = 47/95 (49%), Gaps = 5/95 (5%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAA 162
QQQQQQQQQQQQQQQQQQQQQQQQQ S P + A ++ GL A A
Sbjct: 1245 QQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMD--GLLAGPTMPQAPP 1302
Query: 163 AAVEQRSRF---EYPPPPVSLGSSSHTARLPNGLG 194
+ + + P P SS A + + +G
Sbjct: 1303 QQFPYQPNYGMGQQPDPAFGRVSSPPNAMMSSRMG 1337
Score = 30.0 bits (66), Expect = 8.8
Identities = 34/171 (19%), Positives = 59/171 (34%), Gaps = 20/171 (11%)
Query: 562 EEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGP--------------PPPPPPLGPHS 607
++QQ+QQ Q + + F+ P + P PP P P+
Sbjct: 1252 QQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTMPQAPPQQFPYQPNY 1311
Query: 608 NRTTPPESAPQNGPSPMAALMSVADTLGTAHSP----KDGSSVHSTTASARRNSSSPVSP 663
P+ A SP A+MS +G + +P +S++ ++ S +
Sbjct: 1312 GMGQQPDPAFGRVSSPPNAMMS--SRMGPSQNPMMQHPQAASIYQSSEMKGWPSGNLARN 1369
Query: 664 ASVPGQRRLASRNGDLNLQVAPPPPSAHPGMDQVHPQNIPDSPMANSGPLC 714
+S Q+ N + V S H G ++P + PM C
Sbjct: 1370 SSFSQQQFAHQGNPAVYSMVHMNGSSGHMGQMNMNPMPMSGMPMGPDQKYC 1420
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 58.5 bits (140), Expect = 2e-08
Identities = 80/275 (29%), Positives = 98/275 (35%), Gaps = 59/275 (21%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQ-----LNHVDGSSKPAVLAAPSGLERYGLSAAA 155
A QQQ Q QQQQQQQQQQQQQQQQQQ N + G+ A P +E+ A
Sbjct: 47 ALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD-MEQPQHGGAK 105
Query: 156 AAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEG------PP 209
+AA A PP P L P +G P G P G PP
Sbjct: 106 DSAAGGQAD---------PPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPP 156
Query: 210 ELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTV-PPNLLPQTLLNGPASA 268
P A+V +G PGG GP P + ASA
Sbjct: 157 V---AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213
Query: 269 AVLPPPPPHALGSRGP----------------PTPAPPGAPGGPACLGGTPGVS------ 306
A P GS P P + PGA GG GG G S
Sbjct: 214 AAAGAP-----GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268
Query: 307 -------ATSSSASSSTSSSVAEVGVGAGGKRPGS 334
A + + +++ +++ A G G GG GS
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303
Score = 39.7 bits (91), Expect = 0.011
Identities = 145/677 (21%), Positives = 221/677 (32%), Gaps = 207/677 (30%)
Query: 77 GVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSK 136
G ++ + +A+AAAA A + Q + Q NH G S+
Sbjct: 199 GQQSPGMGMMHSASAAAAGAPGS-------------MDPLQNSHEGYPNSQCNHYPGYSR 245
Query: 137 PAVLAAP------------------SGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPV 178
P +G G A AAAAAAAAAA
Sbjct: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA------------- 292
Query: 179 SLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTG 238
G GG G+ SS+ ++S R GG++ G
Sbjct: 293 -------------GGGGGGGYG----------------GSSAGYGVLSSPRQQGGGMMMG 323
Query: 239 LPNPGGGGGPQLT--------------VPPNLLPQTLLNGPASAAVLPPPPPHALGSRGP 284
PGGGG L+ N P P P + G P
Sbjct: 324 ---PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYP 380
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQEREL 344
+P P P+ P A ++ A++ + A +G+G K G+ +
Sbjct: 381 EYSSPSAPPPPPS----QPQSQAAAAGAAAGGQQAAAGMGLG---KDMGAQYAAASPAWA 433
Query: 345 KEKQRNAEALAELSES-LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVF 403
+QR+ A++ + R++ P +++ L G P+
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH--------------- 478
Query: 404 AFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYE 463
S+P YP GS Q Y ++ G +G +Y + +
Sbjct: 479 -----SQPQQSSP------YPGGS------YGPPGPQRYPIGIQGRTPGAMAGMQYPQ-Q 520
Query: 464 KKHGSGDWRLLGDLLPEAVRFFKEGVPG-ADMLPQPYLDASC--PMLPTA---LVSLSRA 517
+ G W+ L+P ++ ++GV G QPY P LP L S S+
Sbjct: 521 QDSGDATWKETFWLMPP--QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQ 578
Query: 518 PSAPP--------GTGALPPAAPSGRGAAASL----RKRKASPEPPDSAEGALKLGEEQQ 565
P GT + PP AP G+ L ++R +S + L G E
Sbjct: 579 RYQPQQDMSQEGYGTRSQPPLAP-GKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE-- 635
Query: 566 RQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMA 625
A S A+ ++G ++ G + P P PH++ P S+ GPSP
Sbjct: 636 -----ATLSSAVS---ASGSTSSQGDQSN---PAQSPFSPHAS---PHLSSIPGGPSPSP 681
Query: 626 ALMSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAP 685
GS V S ++ S P+SPAS+PG Q+ P
Sbjct: 682 V----------------GSPVGSN-----QSRSGPISPASIPGS------------QMPP 708
Query: 686 PPP------SAHPGMDQ 696
PP S+HP + Q
Sbjct: 709 QPPGSQSESSSHPALSQ 725
Score = 33.5 bits (75), Expect = 0.80
Identities = 60/267 (22%), Positives = 90/267 (33%), Gaps = 39/267 (14%)
Query: 67 GRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQ 126
G S G G A AAAAAAAAAAA +QQ
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 127 QLNHVDGS-----SKPAVLAAPSGLERYG----------------LSAAAAAAAAAAAAV 165
+ G SK A +A G +R+ L++ + + +
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 166 EQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASV 225
+ S PPPP S S A G G + G + + + ++++ A
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAA-----AGAAAGGQQAAAGMGLGK-DMGAQYAAASPAWA 433
Query: 226 ASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPP 285
A+++ +H + G P P G + P ++ + L G S PH+ + P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGS-------NPHSQPQQSSP 486
Query: 286 TPAPPGAPGGP-----ACLGGTPGVSA 307
P P GP G TPG A
Sbjct: 487 YPGGSYGPPGPQRYPIGIQGRTPGAMA 513
Score = 32.3 bits (72), Expect = 1.8
Identities = 51/200 (25%), Positives = 76/200 (38%), Gaps = 22/200 (11%)
Query: 519 SAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALK 578
S+P G P G G AASL K A SA G + Q + A +
Sbjct: 311 SSPRQQGGGMMMGPGG-GGAASLSKAAAG-----SAAGGFQRFAGQNQHPSGATPTLNQL 364
Query: 579 LT-----MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADT 633
LT M + G + P +++ PPPPP P S +A G AA M +
Sbjct: 365 LTSPSPMMRSYGGSYPEYSSPSAPPPPPS-QPQSQAAAAGAAA---GGQQAAAGMGLGKD 420
Query: 634 LGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPG 693
+G + ++ A+A++ S +SP + PG S+ ++ V P G
Sbjct: 421 MGAQY-----AAASPAWAAAQQRSHPAMSPGT-PGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Query: 694 MD-QVHPQNIPDSPMANSGP 712
+ PQ P + GP
Sbjct: 475 SNPHSQPQQSSPYPGGSYGP 494
Score = 31.6 bits (70), Expect = 3.0
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 17/86 (19%)
Query: 263 NGPASAAVLPPPPPHALGSRGPPTPAPPGAPGG----------PACLGGT------PGVS 306
+ PA + P PH G P+P+P G+P G PA + G+ PG
Sbjct: 655 SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQ 714
Query: 307 ATSSS-ASSSTSSSVAEVGVGAGGKR 331
+ SSS + S S E G AG +R
Sbjct: 715 SESSSHPALSQSPMPQERGFMAGTQR 740
Score = 30.8 bits (68), Expect = 5.2
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 65 QDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQ 124
Q G GPP P TV A+EAAAA AAA +AQ +Q Q
Sbjct: 868 QGGPGMGPPMP----TVNRKAQEAAAAV--MQAAANSAQSRQGSFPGMNQSGLMASSSPY 921
Query: 125 QQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYP 174
Q +N + SS A P + ++++AA+ A S+ P
Sbjct: 922 SQPMN--NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 969
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 58.5 bits (140), Expect = 2e-08
Identities = 80/275 (29%), Positives = 98/275 (35%), Gaps = 59/275 (21%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQ-----LNHVDGSSKPAVLAAPSGLERYGLSAAA 155
A QQQ Q QQQQQQQQQQQQQQQQQQ N + G+ A P +E+ A
Sbjct: 47 ALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD-MEQPQHGGAK 105
Query: 156 AAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEG------PP 209
+AA A PP P L P +G P G P G PP
Sbjct: 106 DSAAGGQAD---------PPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPP 156
Query: 210 ELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTV-PPNLLPQTLLNGPASA 268
P A+V +G PGG GP P + ASA
Sbjct: 157 V---AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213
Query: 269 AVLPPPPPHALGSRGP----------------PTPAPPGAPGGPACLGGTPGVS------ 306
A P GS P P + PGA GG GG G S
Sbjct: 214 AAAGAP-----GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268
Query: 307 -------ATSSSASSSTSSSVAEVGVGAGGKRPGS 334
A + + +++ +++ A G G GG GS
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303
Score = 37.4 bits (85), Expect = 0.055
Identities = 48/189 (25%), Positives = 72/189 (38%), Gaps = 34/189 (17%)
Query: 65 QDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQ 124
Q G GPP P TV A+EAAAA AAA +AQ +Q Q
Sbjct: 855 QGGPGMGPPMP----TVNRKAQEAAAAV--MQAAANSAQSRQGSFPGMNQSGLMASSSPY 908
Query: 125 QQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYP---------- 174
Q +N + SS A P + ++++AA+ A S+ P
Sbjct: 909 SQPMN--NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGT 966
Query: 175 PPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGG 234
P P S S++++ + P P P+P SP+S+S ++ HG
Sbjct: 967 PQPESKSKDSYSSQGISQPPTPGNLPVPSP---------MSPSSASISS-------FHGD 1010
Query: 235 LVTGLPNPG 243
+ +PG
Sbjct: 1011 ESDSISSPG 1019
Score = 37.0 bits (84), Expect = 0.072
Identities = 135/665 (20%), Positives = 215/665 (32%), Gaps = 96/665 (14%)
Query: 67 GRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQ 126
G S G G A AAAAAAAAAAA +QQ
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 127 QLNHVDGS-----SKPAVLAAPSGLERYG----------------LSAAAAAAAAAAAAV 165
+ G SK A +A G +R+ L++ + + +
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 166 EQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASV 225
+ S PPPP S S A G G + G + + + ++++ A
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAA-----AGAAAGGQQAAAGMGLGK-DMGAQYAAASPAWA 433
Query: 226 ASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPP 285
A+++ +H + G P P G + P ++ + L G S PH+ + P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGS-------NPHSQPQQSSP 486
Query: 286 TPAPPGAPGGP-----ACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQ 340
P P GP G TPG A + GV +G + G Q
Sbjct: 487 YPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGV-SGYCQQGQQPYYSQ 545
Query: 341 ERELKEKQRNAEALAELSESLRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLG 400
+ + A+ L S+ ++ + + R G K +H L
Sbjct: 546 QPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG--------KPNHEDLN 597
Query: 401 RVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYL 460
+ S P + + + PTG+ SSA V+ D S F
Sbjct: 598 LIQQERPSSLPDLSGSID---DLPTGTEATLSSA--VSASGSTSSQGDQSNPAQSPFS-- 650
Query: 461 EYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSA 520
+ H S +PG P P P+ S +P++
Sbjct: 651 PHASPHLS-------------------SIPGGPS-PSP---VGSPVGSNQSRSGPISPAS 687
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PG+ +PP P + ++S SP P + A Q Q ++
Sbjct: 688 IPGS-QMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPH 746
Query: 581 MSAGGFAAPG-------HAAGGPPPPPPPLGPHSNRTTPP-----ESAPQNGPSPMAALM 628
S GG G +++G P GP N + PP SA +GP P +
Sbjct: 747 PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS 806
Query: 629 SVADTLGTAHSPKDGSSVHSTTASA-RRNSSSPVSPASV-PGQRRLASRNGDLNLQVAPP 686
+ G S G+ SA +N P + +S+ P ++ + G + PP
Sbjct: 807 ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGP---GMGPP 863
Query: 687 PPSAH 691
P+ +
Sbjct: 864 MPTVN 868
Score = 33.5 bits (75), Expect = 0.80
Identities = 130/660 (19%), Positives = 205/660 (31%), Gaps = 186/660 (28%)
Query: 77 GVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSK 136
G ++ + +A+AAAA A + Q + Q NH G S+
Sbjct: 199 GQQSPGMGMMHSASAAAAGAPGS-------------MDPLQNSHEGYPNSQCNHYPGYSR 245
Query: 137 PAVLAAP------------------SGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPV 178
P +G G A AAAAAAAAAA
Sbjct: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA------------- 292
Query: 179 SLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTG 238
G GG G+ SS+ ++S R GG++ G
Sbjct: 293 -------------GGGGGGGYG----------------GSSAGYGVLSSPRQQGGGMMMG 323
Query: 239 LPNPGGGGGPQLT--------------VPPNLLPQTLLNGPASAAVLPPPPPHALGSRGP 284
PGGGG L+ N P P P + G P
Sbjct: 324 ---PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYP 380
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQEREL 344
+P P P+ P A ++ A++ + A +G+G K G+ +
Sbjct: 381 EYSSPSAPPPPPS----QPQSQAAAAGAAAGGQQAAAGMGLG---KDMGAQYAAASPAWA 433
Query: 345 KEKQRNAEALAELSES-LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVF 403
+QR+ A++ + R++ P +++ L G P+
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH--------------- 478
Query: 404 AFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYE 463
S+P YP GS Q Y ++ G +G +Y + +
Sbjct: 479 -----SQPQQSSP------YPGGS------YGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ 521
Query: 464 KKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQP-YLDASCPMLPTALVSLSRAPSAPP 522
G + G ++ + + PQ YL + +S+
Sbjct: 522 MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTR 581
Query: 523 GTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMS 582
L P P+ ++R +S + L G E A S A+ +
Sbjct: 582 SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE-------ATLSSAVS---A 631
Query: 583 AGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKD 642
+G ++ G + P P PH++ P S+ GPSP
Sbjct: 632 SGSTSSQGDQSN---PAQSPFSPHAS---PHLSSIPGGPSPSPV---------------- 669
Query: 643 GSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPP------SAHPGMDQ 696
GS V S ++ S P+SPAS+PG Q+ P PP S+HP + Q
Sbjct: 670 GSPVGSN-----QSRSGPISPASIPGS------------QMPPQPPGSQSESSSHPALSQ 712
Score = 32.3 bits (72), Expect = 1.8
Identities = 51/200 (25%), Positives = 76/200 (38%), Gaps = 22/200 (11%)
Query: 519 SAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALK 578
S+P G P G G AASL K A SA G + Q + A +
Sbjct: 311 SSPRQQGGGMMMGPGG-GGAASLSKAAAG-----SAAGGFQRFAGQNQHPSGATPTLNQL 364
Query: 579 LT-----MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADT 633
LT M + G + P +++ PPPPP P S +A G AA M +
Sbjct: 365 LTSPSPMMRSYGGSYPEYSSPSAPPPPPS-QPQSQAAAAGAAA---GGQQAAAGMGLGKD 420
Query: 634 LGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPG 693
+G + ++ A+A++ S +SP + PG S+ ++ V P G
Sbjct: 421 MGAQY-----AAASPAWAAAQQRSHPAMSPGT-PGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Query: 694 MD-QVHPQNIPDSPMANSGP 712
+ PQ P + GP
Sbjct: 475 SNPHSQPQQSSPYPGGSYGP 494
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 58.5 bits (140), Expect = 2e-08
Identities = 80/275 (29%), Positives = 98/275 (35%), Gaps = 59/275 (21%)
Query: 101 AAQQQQQQQQQQQQQQQQQQQQQQQQQ-----LNHVDGSSKPAVLAAPSGLERYGLSAAA 155
A QQQ Q QQQQQQQQQQQQQQQQQQ N + G+ A P +E+ A
Sbjct: 47 ALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPD-MEQPQHGGAK 105
Query: 156 AAAAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEG------PP 209
+AA A PP P L P +G P G P G PP
Sbjct: 106 DSAAGGQAD---------PPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPP 156
Query: 210 ELNRQSPNSSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTV-PPNLLPQTLLNGPASA 268
P A+V +G PGG GP P + ASA
Sbjct: 157 V---AVPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASA 213
Query: 269 AVLPPPPPHALGSRGP----------------PTPAPPGAPGGPACLGGTPGVS------ 306
A P GS P P + PGA GG GG G S
Sbjct: 214 AAAGAP-----GSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGG 268
Query: 307 -------ATSSSASSSTSSSVAEVGVGAGGKRPGS 334
A + + +++ +++ A G G GG GS
Sbjct: 269 GGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGS 303
Score = 37.0 bits (84), Expect = 0.072
Identities = 135/665 (20%), Positives = 215/665 (32%), Gaps = 96/665 (14%)
Query: 67 GRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQ 126
G S G G A AAAAAAAAAAA +QQ
Sbjct: 260 GGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGG 319
Query: 127 QLNHVDGS-----SKPAVLAAPSGLERYG----------------LSAAAAAAAAAAAAV 165
+ G SK A +A G +R+ L++ + + +
Sbjct: 320 MMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSY 379
Query: 166 EQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASV 225
+ S PPPP S S A G G + G + + + ++++ A
Sbjct: 380 PEYSSPSAPPPPPSQPQSQAAA-----AGAAAGGQQAAAGMGLGK-DMGAQYAAASPAWA 433
Query: 226 ASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPP 285
A+++ +H + G P P G + P ++ + L G S PH+ + P
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGS-------NPHSQPQQSSP 486
Query: 286 TPAPPGAPGGP-----ACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQ 340
P P GP G TPG A + GV +G + G Q
Sbjct: 487 YPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGV-SGYCQQGQQPYYSQ 545
Query: 341 ERELKEKQRNAEALAELSESLRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLG 400
+ + A+ L S+ ++ + + R G K +H L
Sbjct: 546 QPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPG--------KPNHEDLN 597
Query: 401 RVFAFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYL 460
+ S P + + + PTG+ SSA V+ D S F
Sbjct: 598 LIQQERPSSLPDLSGSID---DLPTGTEATLSSA--VSASGSTSSQGDQSNPAQSPFS-- 650
Query: 461 EYEKKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQPYLDASCPMLPTALVSLSRAPSA 520
+ H S +PG P P P+ S +P++
Sbjct: 651 PHASPHLS-------------------SIPGGPS-PSP---VGSPVGSNQSRSGPISPAS 687
Query: 521 PPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLT 580
PG+ +PP P + ++S SP P + A Q Q ++
Sbjct: 688 IPGS-QMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPH 746
Query: 581 MSAGGFAAPG-------HAAGGPPPPPPPLGPHSNRTTPP-----ESAPQNGPSPMAALM 628
S GG G +++G P GP N + PP SA +GP P +
Sbjct: 747 PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGIS 806
Query: 629 SVADTLGTAHSPKDGSSVHSTTASA-RRNSSSPVSPASV-PGQRRLASRNGDLNLQVAPP 686
+ G S G+ SA +N P + +S+ P ++ + G + PP
Sbjct: 807 ANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGP---GMGPP 863
Query: 687 PPSAH 691
P+ +
Sbjct: 864 MPTVN 868
Score = 33.5 bits (75), Expect = 0.80
Identities = 130/660 (19%), Positives = 205/660 (31%), Gaps = 186/660 (28%)
Query: 77 GVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSK 136
G ++ + +A+AAAA A + Q + Q NH G S+
Sbjct: 199 GQQSPGMGMMHSASAAAAGAPGS-------------MDPLQNSHEGYPNSQCNHYPGYSR 245
Query: 137 PAVLAAP------------------SGLERYGLSAAAAAAAAAAAAVEQRSRFEYPPPPV 178
P +G G A AAAAAAAAAA
Sbjct: 246 PGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAA------------- 292
Query: 179 SLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPNSSSAAASVASRRGTHGGLVTG 238
G GG G+ SS+ ++S R GG++ G
Sbjct: 293 -------------GGGGGGGYG----------------GSSAGYGVLSSPRQQGGGMMMG 323
Query: 239 LPNPGGGGGPQLT--------------VPPNLLPQTLLNGPASAAVLPPPPPHALGSRGP 284
PGGGG L+ N P P P + G P
Sbjct: 324 ---PGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYP 380
Query: 285 PTPAPPGAPGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRPGSVSSTDQEREL 344
+P P P+ P A ++ A++ + A +G+G K G+ +
Sbjct: 381 EYSSPSAPPPPPS----QPQSQAAAAGAAAGGQQAAAGMGLG---KDMGAQYAAASPAWA 433
Query: 345 KEKQRNAEALAELSES-LRNRAEEWASKPKMVRDTLLTLAGCTPYEVRFKKDHSLLGRVF 403
+QR+ A++ + R++ P +++ L G P+
Sbjct: 434 AAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPH--------------- 478
Query: 404 AFDAVSKPGMDYELKLFIEYPTGSGNVYSSASGVAKQMYQDCMKDFGRGLSSGFKYLEYE 463
S+P YP GS Q Y ++ G +G +Y + +
Sbjct: 479 -----SQPQQSSP------YPGGS------YGPPGPQRYPIGIQGRTPGAMAGMQYPQQQ 521
Query: 464 KKHGSGDWRLLGDLLPEAVRFFKEGVPGADMLPQP-YLDASCPMLPTALVSLSRAPSAPP 522
G + G ++ + + PQ YL + +S+
Sbjct: 522 MPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTR 581
Query: 523 GTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALKLTMS 582
L P P+ ++R +S + L G E A S A+ +
Sbjct: 582 SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTE-------ATLSSAVS---A 631
Query: 583 AGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKD 642
+G ++ G + P P PH++ P S+ GPSP
Sbjct: 632 SGSTSSQGDQSN---PAQSPFSPHAS---PHLSSIPGGPSPSPV---------------- 669
Query: 643 GSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPP------SAHPGMDQ 696
GS V S ++ S P+SPAS+PG Q+ P PP S+HP + Q
Sbjct: 670 GSPVGSN-----QSRSGPISPASIPGS------------QMPPQPPGSQSESSSHPALSQ 712
Score = 32.3 bits (72), Expect = 1.8
Identities = 51/200 (25%), Positives = 76/200 (38%), Gaps = 22/200 (11%)
Query: 519 SAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSEALK 578
S+P G P G G AASL K A SA G + Q + A +
Sbjct: 311 SSPRQQGGGMMMGPGG-GGAASLSKAAAG-----SAAGGFQRFAGQNQHPSGATPTLNQL 364
Query: 579 LT-----MSAGGFAAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADT 633
LT M + G + P +++ PPPPP P S +A G AA M +
Sbjct: 365 LTSPSPMMRSYGGSYPEYSSPSAPPPPPS-QPQSQAAAAGAAA---GGQQAAAGMGLGKD 420
Query: 634 LGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPSAHPG 693
+G + ++ A+A++ S +SP + PG S+ ++ V P G
Sbjct: 421 MGAQY-----AAASPAWAAAQQRSHPAMSPGT-PGPTMGRSQGSPMDPMVMKRPQLYGMG 474
Query: 694 MD-QVHPQNIPDSPMANSGP 712
+ PQ P + GP
Sbjct: 475 SNPHSQPQQSSPYPGGSYGP 494
Score = 30.8 bits (68), Expect = 5.2
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 8/110 (7%)
Query: 65 QDGRSPGPPPPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQ 124
Q G GPP P TV A+EAAAA AAA +AQ +Q Q
Sbjct: 855 QGGPGMGPPMP----TVNRKAQEAAAAV--MQAAANSAQSRQGSFPGMNQSGLMASSSPY 908
Query: 125 QQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAAAAAAAAAVEQRSRFEYP 174
Q +N + SS A P + ++++AA+ A S+ P
Sbjct: 909 SQPMN--NSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLP 956
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 57.8 bits (138), Expect = 4e-08
Identities = 29/49 (59%), Positives = 33/49 (67%)
Query: 92 AAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVL 140
A + A QQQQQQQQQQQQQQQQQQQQQQQQQ H+ + +L
Sbjct: 2040 AGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQIL 2088
Score = 56.2 bits (134), Expect = 1e-07
Identities = 28/50 (56%), Positives = 33/50 (66%)
Query: 78 VKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQ 127
+ T+ + + A + A QQQQQQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2027 ISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQ 2076
Score = 55.1 bits (131), Expect = 3e-07
Identities = 34/82 (41%), Positives = 40/82 (48%), Gaps = 5/82 (6%)
Query: 103 QQQQQQQQQQQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPS-----GLERYGLSAAAAA 157
+QQQQQQQQQQQQQQQQQQQQQQQQ H + A P +R GL
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148
Query: 158 AAAAAAAVEQRSRFEYPPPPVS 179
AA + + + P S
Sbjct: 2149 QQTAALVRQLQQQLSNTQPQPS 2170
Score = 50.4 bits (119), Expect = 6e-06
Identities = 27/55 (49%), Positives = 31/55 (56%)
Query: 74 PPVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQL 128
P + T + A + A QQQQQQQQQQQQQQQQQQQQQQQ +
Sbjct: 2025 PMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHI 2079
Score = 49.7 bits (117), Expect = 1e-05
Identities = 26/49 (53%), Positives = 31/49 (63%)
Query: 79 KTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQQQQQQQQ 127
+T +S +A A + A +QQQQQQQQQQQQQQQQQQQQQ
Sbjct: 2023 QTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQ 2071
Score = 47.4 bits (111), Expect = 5e-05
Identities = 25/28 (89%), Positives = 25/28 (89%), Gaps = 3/28 (10%)
Query: 103 QQQQQQ---QQQQQQQQQQQQQQQQQQQ 127
QQQQQQ QQQQQQQQQQQQQQQQQQQ
Sbjct: 2081 QQQQQQILRQQQQQQQQQQQQQQQQQQQ 2108
Score = 47.4 bits (111), Expect = 5e-05
Identities = 25/28 (89%), Positives = 25/28 (89%), Gaps = 3/28 (10%)
Query: 103 QQQQQ---QQQQQQQQQQQQQQQQQQQQ 127
QQQQQ QQQQQQQQQQQQQQQQQQQQ
Sbjct: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQ 2109
Score = 45.4 bits (106), Expect = 2e-04
Identities = 26/56 (46%), Positives = 31/56 (55%), Gaps = 2/56 (3%)
Query: 75 PVGVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQQQQQQQQQ--QQQQQQQL 128
P+ + V + A QQQQQQQQQQQQQQQQQ +QQQQQQ+
Sbjct: 2032 PMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQI 2087
Score = 45.1 bits (105), Expect = 3e-04
Identities = 28/64 (43%), Positives = 33/64 (51%), Gaps = 13/64 (20%)
Query: 77 GVKTVALSAKEAAAAAAAAAAAAAAAQQQQQQQQQQ-------------QQQQQQQQQQQ 123
GV++ A+ ++ QQQQQQQQQQ QQQQQQQQQQQ
Sbjct: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
Query: 124 QQQQ 127
QQQQ
Sbjct: 2101 QQQQ 2104
>gi|68161546 misshapen/NIK-related kinase isoform 4 [Homo sapiens]
Length = 1312
Score = 57.8 bits (138), Expect = 4e-08
Identities = 75/238 (31%), Positives = 96/238 (40%), Gaps = 43/238 (18%)
Query: 104 QQQQQQQQ------QQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAA 157
Q+Q QQ+ QQQQQQQQ Q+QQQQQL + G KP L YG A
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL--LPGDRKP--------LYHYGRGMNPAD 515
Query: 158 AAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPN 217
A A VE+R+R ++ +S A+ G GP P P GPP Q+P
Sbjct: 516 KPAWAREVEERTR-------MNKQQNSPLAKSKPGSTGPEP-PIPQASPGPPGPLSQTP- 566
Query: 218 SSSAAASVASRRGTHGGLVTGLPNPGGGGGPQLTVPPNLLPQTLLNGPASAAVLPPPPPH 277
V + G H L P P P +P A AV+
Sbjct: 567 --PMQRPVEPQEGPHKSL-QDQPTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDP 623
Query: 278 ALGSRGP-PTPAPPG--APGGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKRP 332
S GP P+P PP P A P V +SS +++ ++S GAGG RP
Sbjct: 624 T--SEGPGPSPNPPAWVRPDNEA----PPKVPQRTSSIATALNTS------GAGGSRP 669
Score = 35.0 bits (79), Expect = 0.27
Identities = 46/187 (24%), Positives = 64/187 (34%), Gaps = 31/187 (16%)
Query: 517 APSAPPGTGALPPAAPSGRGAAASLRKRKASPEPPDSAEGALKLGEEQQRQQWMANQSE- 575
A S P TG PP + G L + P + EG K ++Q + A +
Sbjct: 538 AKSKPGSTGPEPPIPQASPGPPGPLSQTPPMQRPVEPQEGPHKSLQDQPTRNLAAFPASH 597
Query: 576 -------ALKLTMSAGGF-----AAPGHAAGGPPPPPPPLGPHSNRTTPPESAPQNGPSP 623
A T SA G + P GP P PP P AP P
Sbjct: 598 DPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAW------VRPDNEAPPKVPQR 651
Query: 624 MAALMSVADTLGTAHS---------PKDGSS--VHSTTASARRNSSSPVSPASVPGQRRL 672
+++ + +T G S P+ S+ ++ + R P PA PG
Sbjct: 652 TSSIATALNTSGAGGSRPAQAVRARPRSNSAWQIYLQRRAERGTPKPPGPPAQPPGPPN- 710
Query: 673 ASRNGDL 679
AS N DL
Sbjct: 711 ASSNPDL 717
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 57.4 bits (137), Expect = 5e-08
Identities = 80/251 (31%), Positives = 104/251 (41%), Gaps = 49/251 (19%)
Query: 104 QQQQQQQQ------QQQQQQQQQQQQQQQQLNHVDGSSKPAVLAAPSGLERYGLSAAAAA 157
Q+Q QQ+ QQQQQQQQ Q+QQQQQL + G KP L YG A
Sbjct: 466 QRQLQQEHAYLKSLQQQQQQQQLQKQQQQQL--LPGDRKP--------LYHYGRGMNPAD 515
Query: 158 AAAAAAAVEQRSRFEYPPPPVSLGSSSHTARLPNGLGGPNGFPKPTPEEGPPELNRQSPN 217
A A VE+R+R ++ +S A+ G GP P P GPP Q+P
Sbjct: 516 KPAWAREVEERTR-------MNKQQNSPLAKSKPGSTGPEP-PIPQASPGPPGPLSQTP- 566
Query: 218 SSSAAASVASRRGTHGGLVT-GLP-NPGGGGGPQ---LTVPP--NLLPQTLLNGPASAAV 270
V + G H LV +P P P+ L P NL + P A
Sbjct: 567 --PMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQPTRNLAAFPASHDPDPAIP 624
Query: 271 LPPPPPHALGS----RGPPTPAPPG-APGGPACL----GGTPGVSATSSSASSSTSSSVA 321
P P A G+ PT PG +P PA + P V +SS +++ ++S
Sbjct: 625 APTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAPPKVPQRTSSIATALNTS-- 682
Query: 322 EVGVGAGGKRP 332
GAGG RP
Sbjct: 683 ----GAGGSRP 689
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,016,815
Number of Sequences: 37866
Number of extensions: 2942762
Number of successful extensions: 65754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 726
Number of HSP's successfully gapped in prelim test: 1817
Number of HSP's that attempted gapping in prelim test: 24713
Number of HSP's gapped (non-prelim): 24215
length of query: 796
length of database: 18,247,518
effective HSP length: 110
effective length of query: 686
effective length of database: 14,082,258
effective search space: 9660428988
effective search space used: 9660428988
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.