Guide to the Human Genome
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Search of human proteins with 33356170

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33356170 myosin IXB isoform 1 [Homo sapiens]
         (2157 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33356170 myosin IXB isoform 1 [Homo sapiens]                      4281   0.0  
gi|194272142 myosin IXB isoform 2 [Homo sapiens]                     3992   0.0  
gi|156119615 myosin IXA [Homo sapiens]                               1211   0.0  
gi|118402590 myosin XV [Homo sapiens]                                 449   e-125
gi|189083802 myosin VIIA isoform 2 [Homo sapiens]                     437   e-122
gi|189083800 myosin VIIA isoform 3 [Homo sapiens]                     437   e-122
gi|189083798 myosin VIIA isoform 1 [Homo sapiens]                     437   e-122
gi|122937512 myosin VIIB [Homo sapiens]                               437   e-122
gi|154354979 myosin X [Homo sapiens]                                  433   e-120
gi|134288915 myosin IIIB isoform 1 [Homo sapiens]                     403   e-112
gi|134288892 myosin IIIB isoform 2 [Homo sapiens]                     403   e-112
gi|145275208 myosin IIIA [Homo sapiens]                               399   e-110
gi|122937345 myosin VB [Homo sapiens]                                 395   e-109
gi|215982794 myosin VA isoform 2 [Homo sapiens]                       381   e-105
gi|215982791 myosin VA isoform 1 [Homo sapiens]                       381   e-105
gi|153945715 myosin VC [Homo sapiens]                                 379   e-104
gi|92859701 myosin VI [Homo sapiens]                                  367   e-101
gi|27544941 myosin IF [Homo sapiens]                                  367   e-101
gi|194328685 myosin IB isoform 1 [Homo sapiens]                       363   e-99 
gi|44889481 myosin IB isoform 2 [Homo sapiens]                        363   e-99 
gi|240120050 myosin IB isoform 1 [Homo sapiens]                       363   e-99 
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]    361   4e-99
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...   354   6e-97
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...   354   6e-97
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]   353   8e-97
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...   352   2e-96
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...   352   2e-96
gi|4885503 myosin IA [Homo sapiens]                                   351   5e-96
gi|55956916 myosin IE [Homo sapiens]                                  350   7e-96
gi|124494238 myosin IC isoform a [Homo sapiens]                       341   5e-93

>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
          Length = 2157

 Score = 4281 bits (11102), Expect = 0.0
 Identities = 2157/2157 (100%), Positives = 2157/2157 (100%)

Query: 1    MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60
            MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT
Sbjct: 1    MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60

Query: 61   KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120
            KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY
Sbjct: 61   KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120

Query: 121  VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180
            VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG
Sbjct: 121  VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180

Query: 181  SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240
            SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE
Sbjct: 181  SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240

Query: 241  SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300
            SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI
Sbjct: 241  SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300

Query: 301  QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360
            QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED
Sbjct: 301  QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360

Query: 361  YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420
            YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA
Sbjct: 361  YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420

Query: 421  TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480
            TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS
Sbjct: 421  TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480

Query: 481  MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540
            MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA
Sbjct: 481  MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540

Query: 541  NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600
            NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP
Sbjct: 541  NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600

Query: 601  HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660
            HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV
Sbjct: 601  HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660

Query: 661  ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720
            ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA
Sbjct: 661  ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720

Query: 721  QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780
            QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS
Sbjct: 721  QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780

Query: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840
            KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE
Sbjct: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840

Query: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900
            ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE
Sbjct: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900

Query: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960
            QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI
Sbjct: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960

Query: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020
            LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL
Sbjct: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020

Query: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080
            YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG
Sbjct: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080

Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140
            QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK
Sbjct: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140

Query: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200
            VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED
Sbjct: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200

Query: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260
            ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV
Sbjct: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260

Query: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320
            SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA
Sbjct: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320

Query: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380
            AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE
Sbjct: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380

Query: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440
            RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA
Sbjct: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440

Query: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500
            VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES
Sbjct: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500

Query: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560
            VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV
Sbjct: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560

Query: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620
            GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK
Sbjct: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620

Query: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680
            RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH
Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680

Query: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740
            CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA
Sbjct: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740

Query: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800
            NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK
Sbjct: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800

Query: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860
            QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN
Sbjct: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860

Query: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920
            SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL
Sbjct: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920

Query: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980
            KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI
Sbjct: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980

Query: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV 2040
            TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV
Sbjct: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV 2040

Query: 2041 AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP 2100
            AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP
Sbjct: 2041 AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP 2100

Query: 2101 ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG 2157
            ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG
Sbjct: 2101 ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG 2157


>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
          Length = 2022

 Score = 3992 bits (10352), Expect = 0.0
 Identities = 2020/2020 (100%), Positives = 2020/2020 (100%)

Query: 1    MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60
            MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT
Sbjct: 1    MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60

Query: 61   KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120
            KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY
Sbjct: 61   KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120

Query: 121  VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180
            VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG
Sbjct: 121  VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180

Query: 181  SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240
            SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE
Sbjct: 181  SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240

Query: 241  SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300
            SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI
Sbjct: 241  SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300

Query: 301  QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360
            QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED
Sbjct: 301  QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360

Query: 361  YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420
            YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA
Sbjct: 361  YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420

Query: 421  TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480
            TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS
Sbjct: 421  TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480

Query: 481  MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540
            MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA
Sbjct: 481  MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540

Query: 541  NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600
            NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP
Sbjct: 541  NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600

Query: 601  HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660
            HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV
Sbjct: 601  HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660

Query: 661  ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720
            ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA
Sbjct: 661  ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720

Query: 721  QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780
            QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS
Sbjct: 721  QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780

Query: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840
            KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE
Sbjct: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840

Query: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900
            ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE
Sbjct: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900

Query: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960
            QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI
Sbjct: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960

Query: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020
            LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL
Sbjct: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020

Query: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080
            YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG
Sbjct: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080

Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140
            QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK
Sbjct: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140

Query: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200
            VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED
Sbjct: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200

Query: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260
            ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV
Sbjct: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260

Query: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320
            SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA
Sbjct: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320

Query: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380
            AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE
Sbjct: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380

Query: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440
            RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA
Sbjct: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440

Query: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500
            VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES
Sbjct: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500

Query: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560
            VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV
Sbjct: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560

Query: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620
            GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK
Sbjct: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620

Query: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680
            RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH
Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680

Query: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740
            CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA
Sbjct: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740

Query: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800
            NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK
Sbjct: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800

Query: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860
            QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN
Sbjct: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860

Query: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920
            SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL
Sbjct: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920

Query: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980
            KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI
Sbjct: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980

Query: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG 2020
            TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG
Sbjct: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG 2020


>gi|156119615 myosin IXA [Homo sapiens]
          Length = 2548

 Score = 1211 bits (3133), Expect = 0.0
 Identities = 673/1283 (52%), Positives = 835/1283 (65%), Gaps = 131/1283 (10%)

Query: 7    GSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLV 66
            G   R E   + L IYP  + +E    C + A K+ST ++VI+  I  L LD TKCYVL 
Sbjct: 6    GGRRRFEDNEHTLRIYPG-AISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKCYVLA 64

Query: 67   EVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLV 126
            EVKE GGEEW+L+  D PV R++LWPR A +     + Y FLL+E+N DG+I Y  +Q  
Sbjct: 65   EVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGSLQSW 124

Query: 127  AQATATRR-LVERGLLPR-QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILV 184
             + T  RR ++ERG LP+ QQ DFDDLC+LP+L E  LL+NL++RF  +KIYTY GSIL+
Sbjct: 125  LRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILI 184

Query: 185  AINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSG 244
             INPFKFLPIYNPKYVKMY+N QLGKLEPH++A+ADVAY+ ML+++ NQCIVISGESGSG
Sbjct: 185  VINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSG 244

Query: 245  KTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSY 304
            KTQSTNFLIH LTALSQKG+ASGVE+ ILGAGPVLEAFGNAKTAHNNNSSRFGKFIQV+Y
Sbjct: 245  KTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNY 304

Query: 305  LESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYL 364
             E+G V GA VEKYLLEKSRLV QE +ERNYHVFYYLL G SE+ER  F LKQPE+Y YL
Sbjct: 305  QETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYL 364

Query: 365  NQHNLK------------------IEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLS 406
            NQ   K                    +GEDL+HDFERL+ AMEMVGFLP T++QIF++LS
Sbjct: 365  NQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLS 424

Query: 407  AILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLI 466
            AIL+LGN+ YKK+ T R++ +++  PEVL  +S+LL+VK E+L E L  RKTVTV +KLI
Sbjct: 425  AILHLGNICYKKK-TYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLI 483

Query: 467  LPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFED 526
            LPY L+EA+T R+SMAKSLYSALFDWIV RINHALLN KD+E     LSIGVLDIFGFED
Sbjct: 484  LPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFED 543

Query: 527  FERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKP 586
            +E NSFEQFCIN+ANE+LQ+YFNQHIFKLEQEEY+ EGI+WHNI Y DN  CI+LISKKP
Sbjct: 544  YENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKP 603

Query: 587  TGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKD 646
            TGL +LLDEESNFP AT+QTLL KFK QHEDN Y     VMEPAFII+H+AGKVKY +KD
Sbjct: 604  TGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKD 663

Query: 647  FREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRA 706
            FREKN D+MRPDIVALLR S ++++  +IG+DPVAVFRWA+LRA  RAM   REAG+   
Sbjct: 664  FREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNI 723

Query: 707  ERAEK---------AAGMSSPGAQSHPE-----ELPRGASTPSEKLYRDLHNQMIKSIKG 752
             R               M S     HP      E+ +        + R      +  ++G
Sbjct: 724  HRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQG 783

Query: 753  L--------------PWQGE---------DPRSLLQ---------SLSRLQKPRAFILKS 780
            +               W G             SLL          S   L++    + ++
Sbjct: 784  MNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRN 843

Query: 781  KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840
            K  K K  +PK+LL+  SLK +  +TL DR TKSLLHLHKKKKPPSISAQFQ SL+KL+E
Sbjct: 844  KNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLME 903

Query: 841  ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900
             LG+AEP+F++CIRSNAEK  L F D LVL+QLRYTGMLETVRIR+SGYS+KY+FQDF  
Sbjct: 904  TLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVS 963

Query: 901  QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960
             F VLLP++  P +  I     K+ ++  NYQ+GKT VFLKE ERQ LQ+ LH+EV+R+I
Sbjct: 964  HFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRI 1023

Query: 961  LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSY----RVR-------------------- 996
            +LLQ WFR++L R+HFL +++A+V IQ  WR+Y    +VR                    
Sbjct: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQA 1083

Query: 997  ---------RALERTQAAVYLQASWRGYWQR------------------KLYRHQKQSII 1029
                     R LE   AA+ +Q  WR Y++R                  K Y+ Q++ II
Sbjct: 1084 SWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKII 1143

Query: 1030 RLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQ------- 1082
             LQS CRG   R+ F + + E++  E K    L   +       QG    G +       
Sbjct: 1144 LLQSTCRGFRARQRF-KALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNR 1202

Query: 1083 -VAEQGPEPAEDGGHLASEPEVQPSDRSP---LEHSSPEKEAPSPEKTLPPQKTVAAESH 1138
              A +  +   +   ++ E  V     SP    E +  +      E  L  ++  + E  
Sbjct: 1203 IKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDL 1262

Query: 1139 EKVPSSREKRESRRQRGLEHVKF 1161
             +    R KRESRR R LE   F
Sbjct: 1263 HQKKVGRAKRESRRMRELEQAIF 1285



 Score =  449 bits (1155), Expect = e-125
 Identities = 240/561 (42%), Positives = 362/561 (64%), Gaps = 34/561 (6%)

Query: 1471 KRTKEPGGKGKKNRNVKIGKITV-SEKWRESVFRQITNANELKYLDEFLLNKINDLRSQK 1529
            K  KEP  K K+ R+VKI  + + S  W+    + I + ++LK +DEFLL K+NDL ++ 
Sbjct: 1823 KENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNED 1882

Query: 1530 ----TPIESLFIEATEKFRSNIKTMYS----VPNGKIHVGYKDLMENY-QIVVSNLATER 1580
                T ++ +F +A ++FR NI + YS    + +GK  + YKDL   + QI+   +  E+
Sbjct: 1883 SKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGK-SIRYKDLYALFEQILEKTMRLEQ 1941

Query: 1581 ----GQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERA--VQEHNGHV 1634
                G+    + +N F+  LDE+   +  +D    K  K ++KKR+++    V+EHNGH+
Sbjct: 1942 RDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHI 2001

Query: 1635 FASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVE 1694
            F + Q SIP  CE C S IW+MD+A +C +CK  CHKKC  K  + CS  Y    +P + 
Sbjct: 2002 FKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKY----DPELS 2057

Query: 1695 PGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1754
               FGV +  LTS+  +VP+V+EKL+ ++EMHGLYTEG+YRKSG+ N+ +ELRQ L TD 
Sbjct: 2058 SRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117

Query: 1755 AAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHL 1814
             +V L+++ IH I  V KQWLR+LP PLMTF  Y +FLRA+ L E++E +  +Y+V++ L
Sbjct: 2118 ESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQL 2177

Query: 1815 PEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1874
               + N+LERLIFHLV++AL ED NRMS  ALAI+FAPC+LRCPD +DPL S++D+ K T
Sbjct: 2178 SRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTT 2237

Query: 1875 TCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQN-APWPLKLG-FSSPYEGVL 1932
            TCVE+++ EQM KYK ++++IS LE AE+ A  RLSL+R++     ++ G +  P   V+
Sbjct: 2238 TCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVV 2297

Query: 1933 NKSPKTRDIQEE--------ELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRL 1984
             + P   D+ EE        E ++  +++AA   E+R   +L E+I+++++EKE++T+ +
Sbjct: 2298 VRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEER---VLTEQIENLQKEKEELTFEM 2354

Query: 1985 PELDPRGSDEENLDSETSAST 2005
              L+PR SD+E L+SE S  T
Sbjct: 2355 LVLEPRASDDETLESEASIGT 2375


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score =  449 bits (1155), Expect = e-125
 Identities = 235/526 (44%), Positives = 337/526 (64%), Gaps = 8/526 (1%)

Query: 149  DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
            +D+  L +L E  +L NLK RF +  IYTY GSILV++NP++   IY P+ V+ Y  + L
Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284

Query: 209  GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
            G+  PH+FA+A++A+  ML  + NQCI+ISGESGSGKT++T  ++  L A++QK      
Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343

Query: 269  ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
            +  IL A P+LE+FGNAKT  N+NSSRFGKF+++ +LE G++ GA+  +YLLEKSR+V Q
Sbjct: 1344 QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVFQ 1402

Query: 329  EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388
             K+ERNYH+FY LL G+  + RQ F L++ E Y+YLNQ       G+    DF RL  AM
Sbjct: 1403 AKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAM 1462

Query: 389  EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448
            E++GF    +  IF +L++IL+LGNV ++K  T  +E   V     +  +++LL++  E 
Sbjct: 1463 EVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPEG 1522

Query: 449  LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508
            L + +T + T T+ +K+  P ++  A+ ARD++AK LY+ LF W++ R+N  +  ++D  
Sbjct: 1523 LQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQDT- 1581

Query: 509  EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568
                 LSI +LDI+GFED   NSFEQ CINYANE LQY FN+ +F+ EQEEY  E I W 
Sbjct: 1582 -----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQ 1636

Query: 569  NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVME 628
             I + DN  CI+LIS KP G+  +LD++  FP AT  T L K    H  N  +    +  
Sbjct: 1637 EITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPL 1696

Query: 629  PAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674
            P F I+H+AGKV YQ+  F +KN D +R D++ L   S +  V  L
Sbjct: 1697 PEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHL 1742



 Score =  122 bits (306), Expect = 4e-27
 Identities = 94/340 (27%), Positives = 160/340 (47%), Gaps = 62/340 (18%)

Query: 823  KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882
            K  +++A+FQ SL  L+E + +  P F+RC++ N +K+   F+ ++V+ QLRY+G+LETV
Sbjct: 1766 KAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETV 1825

Query: 883  RIRRSGYSAKYTFQDFTEQFQVL------LPKDAQPCREVISTLLEKMKIDKRNYQIGKT 936
            RIR+ G+  +  FQ F +++  L      LP +   C  V+S L    K+    Y++G +
Sbjct: 1826 RIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRL---CKVMPNMYRVGVS 1882

Query: 937  KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
            K+FLKE   Q L+                       R H L +  AA+T+Q C R + ++
Sbjct: 1883 KLFLKEHLYQLLESM---------------------REHVLNL--AALTLQRCLRGFFIK 1919

Query: 997  RALERTQ-AAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF----------- 1044
            R     +   + LQ+  RGY  R+ Y+  ++S+++ +SL   ++ R+ +           
Sbjct: 1920 RRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQV 1979

Query: 1045 -SQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEV 1103
               ++ E+++  ++E  A+      AE  G  QA  G                LA  P+V
Sbjct: 1980 EGALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGL--------------GLAQVPQV 2025

Query: 1104 QPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPS 1143
             P  R+P   + P    P      P  K V  + H K P+
Sbjct: 2026 APV-RTPRLQAEPRVTLPLDINNYPMAKFV--QCHFKEPA 2062



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 9/143 (6%)

Query: 2007 SLLEERAGRGASEGPPAPALPCPGAP-TPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIM 2065
            SL E  A R A+     P  P PG+P  PSP   +   PRR   +  +    T RR    
Sbjct: 819  SLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEP 878

Query: 2066 PTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGALE 2125
            PT  +K    LP H P   P A    AP+  RE P R P+   + +  P         + 
Sbjct: 879  PTRAVKPQVRLPFHRP---PRAGAWRAPLEHRESP-REPEDSETPWTVPPLAPSWDVDMP 934

Query: 2126 PLEEDGQP----PGAKRRYSDPP 2144
            P +    P     G++R +S PP
Sbjct: 935  PTQRPPSPWPGGAGSRRGFSRPP 957


>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
          Length = 2175

 Score =  437 bits (1124), Expect = e-122
 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           +D+  L +L E  +L+NL  R+    IYTY GSILVA+NP++ L IY+P++++ Y N+++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
           G++ PH+FA+AD  Y+ M R   +QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           E+ +L A P+LEAFGNAKT  N+NSSRFGK+I + + + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388
             DERNYHVFY +L G+SE+++++  L Q  DY YL   N    +G     ++  ++ AM
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305

Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448
           +++ F      +I  +L+AIL+LGN+ Y+ R     +  EV     L T + LL+V    
Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365

Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508
           L+  LT R  +T  + +  P S  +A+  RD+  K +Y  LF WIV +IN A+      +
Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425

Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568
              S  SIG+LDIFGFE+F  NSFEQ CIN+ANE LQ +F +H+FKLEQEEY  E I W 
Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485

Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627
           +I +TDN   + +I+ KP  +  L+DEES FP  T  T+L K   QH+ N  Y       
Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545

Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678
           E  F I HFAG V Y+ + F EKN D +  DI+ L+  S + +++++   D
Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596



 Score =  162 bits (409), Expect = 4e-39
 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%)

Query: 821  KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880
            +K+ P++S+QF+ SL  L+  LG  +PFF+RCI+ N  KK + FD  L ++QLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 881  TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935
            T+RIRR+GY  +Y+F +F E+++VLLP  K A      R     + E +     ++QIGK
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723

Query: 936  TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995
            TK+FLK+     L+    + +  +++LLQ   R   +R +FL++K AA  IQ  WR +  
Sbjct: 724  TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783

Query: 996  RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
            R+             AL R+           Q  +  QA  R Y  RK +RH+  +++ +
Sbjct: 784  RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843

Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091
            Q+  RG + R+     + ++ +AE   R   E  R   EE         +   E   + A
Sbjct: 844  QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889

Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144
            ++      +  +    R   E    EKEA   +K L  Q   A   HE V  S
Sbjct: 890  KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940


>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
          Length = 1204

 Score =  437 bits (1124), Expect = e-122
 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           +D+  L +L E  +L+NL  R+    IYTY GSILVA+NP++ L IY+P++++ Y N+++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
           G++ PH+FA+AD  Y+ M R   +QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           E+ +L A P+LEAFGNAKT  N+NSSRFGK+I + + + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388
             DERNYHVFY +L G+SE+++++  L Q  DY YL   N    +G     ++  ++ AM
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305

Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448
           +++ F      +I  +L+AIL+LGN+ Y+ R     +  EV     L T + LL+V    
Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365

Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508
           L+  LT R  +T  + +  P S  +A+  RD+  K +Y  LF WIV +IN A+      +
Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425

Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568
              S  SIG+LDIFGFE+F  NSFEQ CIN+ANE LQ +F +H+FKLEQEEY  E I W 
Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485

Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627
           +I +TDN   + +I+ KP  +  L+DEES FP  T  T+L K   QH+ N  Y       
Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545

Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678
           E  F I HFAG V Y+ + F EKN D +  DI+ L+  S + +++++   D
Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596



 Score =  162 bits (409), Expect = 4e-39
 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%)

Query: 821  KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880
            +K+ P++S+QF+ SL  L+  LG  +PFF+RCI+ N  KK + FD  L ++QLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 881  TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935
            T+RIRR+GY  +Y+F +F E+++VLLP  K A      R     + E +     ++QIGK
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723

Query: 936  TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995
            TK+FLK+     L+    + +  +++LLQ   R   +R +FL++K AA  IQ  WR +  
Sbjct: 724  TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783

Query: 996  RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
            R+             AL R+           Q  +  QA  R Y  RK +RH+  +++ +
Sbjct: 784  RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843

Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091
            Q+  RG + R+     + ++ +AE   R   E  R   EE         +   E   + A
Sbjct: 844  QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889

Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144
            ++      +  +    R   E    EKEA   +K L  Q   A   HE V  S
Sbjct: 890  KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940


>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
          Length = 2215

 Score =  437 bits (1124), Expect = e-122
 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           +D+  L +L E  +L+NL  R+    IYTY GSILVA+NP++ L IY+P++++ Y N+++
Sbjct: 68  EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
           G++ PH+FA+AD  Y+ M R   +QC +ISGESG+GKT+ST  ++  L A+S  G  S +
Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           E+ +L A P+LEAFGNAKT  N+NSSRFGK+I + + + G + GA +E+YLLEKSR+  Q
Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388
             DERNYHVFY +L G+SE+++++  L Q  DY YL   N    +G     ++  ++ AM
Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305

Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448
           +++ F      +I  +L+AIL+LGN+ Y+ R     +  EV     L T + LL+V    
Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365

Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508
           L+  LT R  +T  + +  P S  +A+  RD+  K +Y  LF WIV +IN A+      +
Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425

Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568
              S  SIG+LDIFGFE+F  NSFEQ CIN+ANE LQ +F +H+FKLEQEEY  E I W 
Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485

Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627
           +I +TDN   + +I+ KP  +  L+DEES FP  T  T+L K   QH+ N  Y       
Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545

Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678
           E  F I HFAG V Y+ + F EKN D +  DI+ L+  S + +++++   D
Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596



 Score =  162 bits (409), Expect = 4e-39
 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%)

Query: 821  KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880
            +K+ P++S+QF+ SL  L+  LG  +PFF+RCI+ N  KK + FD  L ++QLRY+GM+E
Sbjct: 604  RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663

Query: 881  TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935
            T+RIRR+GY  +Y+F +F E+++VLLP  K A      R     + E +     ++QIGK
Sbjct: 664  TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723

Query: 936  TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995
            TK+FLK+     L+    + +  +++LLQ   R   +R +FL++K AA  IQ  WR +  
Sbjct: 724  TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783

Query: 996  RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031
            R+             AL R+           Q  +  QA  R Y  RK +RH+  +++ +
Sbjct: 784  RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843

Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091
            Q+  RG + R+     + ++ +AE   R   E  R   EE         +   E   + A
Sbjct: 844  QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889

Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144
            ++      +  +    R   E    EKEA   +K L  Q   A   HE V  S
Sbjct: 890  KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940


>gi|122937512 myosin VIIB [Homo sapiens]
          Length = 2116

 Score =  437 bits (1123), Expect = e-122
 Identities = 224/538 (41%), Positives = 335/538 (62%), Gaps = 3/538 (0%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P      DD+  L +L E  ++ NL  R+ Q KIYTY GSILVA+NPF+ LP+Y  + V+
Sbjct: 61  PNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQ 120

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQ 261
           +Y ++ +G+L PHVFA+A+  Y++M R + +QC +ISGESG+GKT++T  ++  L  +S 
Sbjct: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS- 179

Query: 262 KGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLE 321
            G  S +E+ +L A P+LEAFGNAKT  N+NSSRFGK+I + +  SG++ GA +E++LLE
Sbjct: 180 -GQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLE 238

Query: 322 KSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDF 381
           KSR+  Q  +ERNYH+FY +L+GVS E++Q   L  P +Y YL   N    +G +   D+
Sbjct: 239 KSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDY 298

Query: 382 ERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQL 441
             ++ AM+++ F  +    +  +L+AIL+LGNV +        +  +V       T+ +L
Sbjct: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKL 358

Query: 442 LKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHAL 501
           L+V+ + L + L K   +   + +    ++++A   RD+  K +Y  LF WIV +IN A+
Sbjct: 359 LEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAI 418

Query: 502 LNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQ 561
                 +      +IG+LDIFGFE+FE NSFEQ CIN+ANE LQ +F QH+F +EQEEY+
Sbjct: 419 FTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478

Query: 562 GEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYF 621
            E I+W  I YTDN   + L++ KP  +  LLDEES FP  T  T+L K    H +NK F
Sbjct: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAF 538

Query: 622 LGTP-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678
           L    + +  F I HFAG+V YQ + F EKN D +  DI+ L+  S + ++RE+  ++
Sbjct: 539 LQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE 596



 Score =  158 bits (399), Expect = 6e-38
 Identities = 94/255 (36%), Positives = 150/255 (58%), Gaps = 14/255 (5%)

Query: 810  RTTKSLLHLHKK----KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFD 865
            R  K+  HL K     K+P ++ +QF+ SL++L++ L   +P+FIRCI+ N  KK L FD
Sbjct: 608  RQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFD 667

Query: 866  DELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQ-----PCREVISTL 920
             EL L+QLRY+GM+ETV IR+SG+  +YTF++F+++F VLLP   +       R++   +
Sbjct: 668  RELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGI 727

Query: 921  LEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK 980
             +      ++++ GKTK+FL++ +   L+    + + R  L +Q   R    R+ FL+ +
Sbjct: 728  TDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQR 787

Query: 981  RAAVTIQACWRSYRVRRALERTQAAV-YLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039
            RAAVT+QA WR Y  RR  +        LQA  R     + Y+  +Q  ++LQ+LCRG+L
Sbjct: 788  RAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYL 847

Query: 1040 QRKSFSQMISEKQKA 1054
             R    Q +  K++A
Sbjct: 848  VR----QQVQAKRRA 858


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score =  433 bits (1113), Expect = e-120
 Identities = 228/555 (41%), Positives = 346/555 (62%), Gaps = 21/555 (3%)

Query: 128 QATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAIN 187
           Q+T T + V   + P  +   DD+ +L EL  G+++ NL  R+ + +IYTY GSIL ++N
Sbjct: 46  QSTITHQKVT-AMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104

Query: 188 PFKFLP-IYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKT 246
           P++ +  +Y P  ++ Y  + LG+L PH+FA+A+  Y  + ++  NQCI+ISGESG+GKT
Sbjct: 105 PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164

Query: 247 QSTNFLIHCLTALSQ-------KGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKF 299
           +ST  ++  L+ +SQ       K   S VER IL + P++EAFGNAKT +NNNSSRFGKF
Sbjct: 165 ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224

Query: 300 IQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPE 359
           +Q++  + G ++G  +  YLLEK+R+V Q   ERNYH+FY LL G+  EER+EF L  PE
Sbjct: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284

Query: 360 DYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR 419
           +Y YLNQ     +     +  F  +  AM+++ F     +++  +L+ IL+LGN+ +   
Sbjct: 285 NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITA 344

Query: 420 ATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARD 479
                 G +V     L   ++LL +    L + LT+R      ++++ P ++ +A+ +RD
Sbjct: 345 G-----GAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRD 399

Query: 480 SMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINY 539
           S+A +LY+  F+W++ +IN  +   +D +      SIG+LDIFGFE+FE N FEQF INY
Sbjct: 400 SLAMALYACCFEWVIKKINSRIKGNEDFK------SIGILDIFGFENFEVNHFEQFNINY 453

Query: 540 ANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNF 599
           ANE+LQ YFN+HIF LEQ EY  EG+ W +I + DN  C+ LI KK  GL  L++EES+F
Sbjct: 454 ANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKK-LGLLALINEESHF 512

Query: 600 PHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDI 659
           P AT  TLL K   QH +N +++   V    F ++H+AG+V+Y ++   EKN D  R D+
Sbjct: 513 PQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDL 572

Query: 660 VALLRGSDSSYVREL 674
           + LLR S   ++ +L
Sbjct: 573 LNLLRESRFDFIYDL 587



 Score =  164 bits (415), Expect = 9e-40
 Identities = 116/366 (31%), Positives = 183/366 (50%), Gaps = 15/366 (4%)

Query: 792  NLLDSKSLKLIISMTLH--DRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFF 849
            NLL       I  +  H   R  +  L    K + P++S+QF+ SL+ L+  L  + PFF
Sbjct: 574  NLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFF 633

Query: 850  IRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKD 909
            +RCI+ N +K    FD  +VL QLRY+GMLETVRIR++GY+ +  FQDF ++++VL+   
Sbjct: 634  VRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL 693

Query: 910  AQP--CREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWF 967
            A P   R   ++LL+        +Q+GKTKVFL+E+  Q L++    EV    +++++  
Sbjct: 694  ALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHV 753

Query: 968  RMVLERRHFLQMKRAAVTIQACWRSYRVRRA-LERTQAAVYLQASWRGYWQRKLYRHQKQ 1026
               L R+ + ++    V IQ  +R++ +RR  L   +AA+  Q   RG   R++YR    
Sbjct: 754  LGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYR---- 809

Query: 1027 SIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQ 1086
                 Q L     Q +   Q   EK+K EE+ERE  E  R  AE   Q +    +Q   +
Sbjct: 810  -----QLLAEKREQEEKKKQEEEEKKKREEEERER-ERERREAELRAQQEEETRKQQELE 863

Query: 1087 GPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSRE 1146
              + ++    L  E E Q  ++   E    EKE    ++    Q+    E+  +    R 
Sbjct: 864  ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR 923

Query: 1147 KRESRR 1152
             +E RR
Sbjct: 924  DQELRR 929


>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
          Length = 1314

 Score =  403 bits (1036), Expect = e-112
 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           DDL NL  L E  ++  L+ R+    IYTY G IL+A+NPF+ L IY+P++ ++Y   + 
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
               PH+FA AD AY  M+    +QCIVISGESGSGKT+S + ++  LT L  K     +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
              IL    ++EAFGN+ TA N+NSSRFGK++++ +  +G+V GA + +YLLEKSR++ Q
Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524

Query: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383
              E+N+H+FYY+  G+  +++  +F+L + +   Y+     +    I   E  +  FE 
Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584

Query: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442
           ++    ++GF       ++ +L+ IL +GN+ +   ++  + +  EV   E L   + +L
Sbjct: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644

Query: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502
            +  E L E LT    VT  + +I   ++  A   RD+M+K+LY  LF WIV RIN  L 
Sbjct: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704

Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562
             +++  A   +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ 
Sbjct: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764

Query: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619
           EGI    + Y DN   + +  +KP GL  LLDEES FP AT QTL+ KF    EDN   K
Sbjct: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820

Query: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679
           YF     +E  F IQH+AGKV Y      EKN D +  D+V +LR S++  +++L  +  
Sbjct: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880

Query: 680 VAVFRWAVLRAAI 692
                 A  RA I
Sbjct: 881 TKTGNLAQTRARI 893



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 61/173 (35%), Positives = 103/173 (59%), Gaps = 10/173 (5%)

Query: 823  KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882
            K  ++++ F+ SL  LL  +   +P F+RCI+ N +++ L F  E VL QLR TG+LETV
Sbjct: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986

Query: 883  RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939
             IRR GYS +  F++F +++  L     Q     +E    +LEK ++D  ++ +GKTKVF
Sbjct: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044

Query: 940  LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQA 988
            LK    + L   L REV+ ++++LQ++ +  L  R + +++    + A+ IQ+
Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096


>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
          Length = 1341

 Score =  403 bits (1036), Expect = e-112
 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           DDL NL  L E  ++  L+ R+    IYTY G IL+A+NPF+ L IY+P++ ++Y   + 
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268
               PH+FA AD AY  M+    +QCIVISGESGSGKT+S + ++  LT L  K     +
Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
              IL    ++EAFGN+ TA N+NSSRFGK++++ +  +G+V GA + +YLLEKSR++ Q
Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524

Query: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383
              E+N+H+FYY+  G+  +++  +F+L + +   Y+     +    I   E  +  FE 
Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584

Query: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442
           ++    ++GF       ++ +L+ IL +GN+ +   ++  + +  EV   E L   + +L
Sbjct: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644

Query: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502
            +  E L E LT    VT  + +I   ++  A   RD+M+K+LY  LF WIV RIN  L 
Sbjct: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704

Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562
             +++  A   +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ 
Sbjct: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764

Query: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619
           EGI    + Y DN   + +  +KP GL  LLDEES FP AT QTL+ KF    EDN   K
Sbjct: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820

Query: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679
           YF     +E  F IQH+AGKV Y      EKN D +  D+V +LR S++  +++L  +  
Sbjct: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880

Query: 680 VAVFRWAVLRAAI 692
                 A  RA I
Sbjct: 881 TKTGNLAQTRARI 893



 Score =  110 bits (274), Expect = 2e-23
 Identities = 95/351 (27%), Positives = 161/351 (45%), Gaps = 43/351 (12%)

Query: 823  KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882
            K  ++++ F+ SL  LL  +   +P F+RCI+ N +++ L F  E VL QLR TG+LETV
Sbjct: 927  KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986

Query: 883  RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939
             IRR GYS +  F++F +++  L     Q     +E    +LEK ++D  ++ +GKTKVF
Sbjct: 987  SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044

Query: 940  LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQACWRSYRV 995
            LK    + L   L REV+ ++++LQ++ +  L  R + +++    + A+ IQ+ WR Y  
Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQSAWRGYDA 1103

Query: 996  RRALE-----RTQAAVYLQA-----------SWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039
            RR  +     R ++A + QA           S      R     Q  S      + RG +
Sbjct: 1104 RRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSV 1163

Query: 1040 QRKSFSQMISEKQKAEEKEREALEAARAG--------------AEEGGQGQAAGGQQVAE 1085
             R+S SQ  S   + +          + G              A    +   +G   ++ 
Sbjct: 1164 HRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSS 1223

Query: 1086 Q--GPEPAEDGGHLASEPEVQPSDRS-PLEHSSPEKEAPSPEKTLPPQKTV 1133
            +   P P + G  L   P+   S+     +H +P +    P+    P+ T+
Sbjct: 1224 RICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTM 1274


>gi|145275208 myosin IIIA [Homo sapiens]
          Length = 1616

 Score =  399 bits (1026), Expect = e-110
 Identities = 218/535 (40%), Positives = 327/535 (61%), Gaps = 8/535 (1%)

Query: 147 DFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQ 206
           D DDL  L  L E  + + L+  + + +IY Y G IL+A+NPF+ L +Y+ K+ K+Y   
Sbjct: 339 DVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGS 398

Query: 207 QLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYAS 266
           +     PH+FA+AD+ Y +M+    +QCIVISGESG+GKT++ + L+  LT L +    +
Sbjct: 399 KRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRT 458

Query: 267 GVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLV 326
            ++  IL    ++EAFGNA T  N+NSSRFGK++++ +  SG V GA + +YLLEKSR++
Sbjct: 459 -LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVI 517

Query: 327 SQEKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDF 381
            Q   E+N+H+FYY+  G++E+++   ++L + +   YL   +L+    I +    K  +
Sbjct: 518 HQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQY 577

Query: 382 ERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQ 440
           E ++Q  +++GF       I+++L+AIL +GN+ +   AT  + +   +     L+  + 
Sbjct: 578 ELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCAS 637

Query: 441 LLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHA 500
           LL ++ + L E LT    VT  + +I P ++ +A   RD+MAK+LY  LF WIV  IN  
Sbjct: 638 LLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSL 697

Query: 501 LLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEY 560
           L +          LSIG+LDIFGFE+F++NSFEQ CIN ANEQ+QYY+NQH+F  EQ EY
Sbjct: 698 LKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEY 757

Query: 561 QGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKY 620
             E +    I Y DN   + +  +KP GL  LLDEES FP AT QTL+ KF + +  ++Y
Sbjct: 758 LNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF-EGNLKSQY 816

Query: 621 FLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELI 675
           F     ME +F I H+AGKV Y    F  KN D +  DIV LLR SD+S +R+L+
Sbjct: 817 FWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871



 Score =  120 bits (302), Expect = 1e-26
 Identities = 114/456 (25%), Positives = 212/456 (46%), Gaps = 48/456 (10%)

Query: 806  TLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFD 865
            T H R T ++       K  ++++ F+ SL  LL  +   +P F+RCI+ N+E++   +D
Sbjct: 912  TRHARETTNM-------KTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYD 964

Query: 866  DELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPCR---EVISTLLE 922
             E VL QLRYTG+LET RIRR G+S +  F +F +++ +L  K ++  R   +  +T+LE
Sbjct: 965  KEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILE 1024

Query: 923  KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQM--- 979
            K  +D  N+ +GKTKVFLK    + L   + +E + K++L+Q+  R  L  R + ++   
Sbjct: 1025 KAGLD--NWALGKTKVFLKYYHVEQL-NLMRKEAIDKLILIQACVRAFLCSRRYQKIQEK 1081

Query: 980  -KRAAVTIQACWRSYRVRRALE-----RTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQS 1033
             K +A+ IQ+  R + VR+  +     +  A   +Q S + +  +K + + ++S ++ Q+
Sbjct: 1082 RKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQA 1141

Query: 1034 ---------LCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVA 1084
                            + S S + +   K EE+   A+E+     +   +      ++V 
Sbjct: 1142 ENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVK 1201

Query: 1085 EQ----GPEPA---------EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQK 1131
            ++    GPE +         E+  +L    + +   +S  +  + E+     +     +K
Sbjct: 1202 QEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERK 1261

Query: 1132 TVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLL 1191
             ++      VP   E  E+  ++ LE    Q    Q+       ++ S  VTQ   +   
Sbjct: 1262 AISERPSYPVPWLAE-NETSFKKTLEPTLSQRSIYQNANSMEKEKKTS-VVTQRAPICSQ 1319

Query: 1192 EDKKESREDETLLVVETEAENTSQKQPTEQPQAMAV 1227
            E+ +     ET  V E + E  +Q Q  E   A+ +
Sbjct: 1320 EEGRGRLRHET--VKERQVEPVTQAQEEEDKAAVFI 1353


>gi|122937345 myosin VB [Homo sapiens]
          Length = 1848

 Score =  395 bits (1016), Expect = e-109
 Identities = 225/536 (41%), Positives = 308/536 (57%), Gaps = 12/536 (2%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207
           +DL  L  L E  +L NLK RFL+   IYTY G +LVAINP++ LPIY    +  Y  Q 
Sbjct: 72  NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131

Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267
           +G ++PH+FA+A+ AY  M R   NQ I++SGESG+GKT S  + +     +      + 
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           +E  +L + P++EA GNAKT  N+NSSRFGK+IQ+ + +   + GA +  YLLEKSR+V 
Sbjct: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
           Q  DERNYH+FY L       E +E  L   ED+FY +Q      +G D   DFE+ +QA
Sbjct: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV-LDTLSQLLKVKR 446
             ++G   + +  IF ++++IL+LG+V  +    G  +   + P +V L    +LL V+ 
Sbjct: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAERDG--DSCSISPQDVYLSNFCRLLGVEH 369

Query: 447 EILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKD 506
             +   L  RK VT ++  +   SL + I AR+++AK +Y+ LF WIV  IN AL     
Sbjct: 370 SQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLK 429

Query: 507 VEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGIT 566
                    IGVLDI+GFE FE NSFEQFCINYANE+LQ  FN H+FKLEQEEY  E I 
Sbjct: 430 QHS-----FIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484

Query: 567 WHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPV 626
           W  I + DN  CI LI  K  G+  LLDEE   P  T Q    K   +H  +++F    +
Sbjct: 485 WTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRM 543

Query: 627 MEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELI--GMDPV 680
              AFII HFA KV+Y    F EKN D +  + + +L+ S    V +L     DPV
Sbjct: 544 SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPV 599



 Score =  122 bits (307), Expect = 3e-27
 Identities = 72/251 (28%), Positives = 135/251 (53%), Gaps = 14/251 (5%)

Query: 810  RTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELV 869
            R+ +  + +  K+   ++  QF+TSL+ L+E L    P ++RCI+ N EK    FD +  
Sbjct: 615  RSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRA 674

Query: 870  LQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPK-------DAQPCREVISTLLE 922
            +QQLR  G+LET+RI  +GY +++ + DF  +++VL+ K           CR V+  L++
Sbjct: 675  VQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIK 734

Query: 923  KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRA 982
                D   +Q G+TK+F +  +   L++    +     +++Q   R  L++  + ++K A
Sbjct: 735  ----DPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGA 790

Query: 983  AVTIQACWRSYRVRRA---LERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039
             +T+Q   R +  RR    L R +AAV LQ  +R    R+ Y+  +++ + +Q+  R   
Sbjct: 791  TLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMF 850

Query: 1040 QRKSFSQMISE 1050
             R+++ Q++ E
Sbjct: 851  VRRTYRQVLME 861



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 68/287 (23%), Positives = 122/287 (42%), Gaps = 34/287 (11%)

Query: 938  VFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR 997
            +F++ T RQ L E        K   +Q   R  + RRHF +++ AA+ IQ  +R  + RR
Sbjct: 849  MFVRRTYRQVLME-------HKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARR 901

Query: 998  ALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQ-SLCRGHLQRKSFSQMISEKQKAEE 1056
             L+    A+ ++A    + +R L    +  +++LQ  +   + + K+ S+ +S       
Sbjct: 902  ELK----ALRIEARSAEHLKR-LNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956

Query: 1057 KEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSP 1116
             E E L+      +E    Q + G+  + +  E  E    L +E +   S+R  LE    
Sbjct: 957  MEVERLK------KELVHYQQSPGEDTSLRLQEEVES---LRTELQRAHSERKILE---- 1003

Query: 1117 EKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVK--FQNKHIQSCKEESA 1174
              +A S EK    +K VA    E      EK +   Q   +      QN   ++  ++  
Sbjct: 1004 --DAHSREKD-ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKEL 1060

Query: 1175 LREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQ 1221
              E SR     +  S LE + ++  DE  ++ +T      ++ P+ Q
Sbjct: 1061 EEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGH---RRNPSNQ 1104


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score =  381 bits (978), Expect = e-105
 Identities = 224/539 (41%), Positives = 307/539 (56%), Gaps = 16/539 (2%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207
           +DL  L  L E  +L NL+ RF+  K IYTY G +LVAINP++ LPIY    +  Y  Q 
Sbjct: 72  NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267
           +G ++PH+FA+A+ AY  M R   NQ I++SGESG+GKT S  + +     +S     + 
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           VE  +L + P++E+ GNAKT  N+NSSRFGK+I++ + +   + GA +  YLLEKSR+V 
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
           Q ++ERNYH+FY L       E +  +L   +++ Y  Q    + +G D   +    +QA
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPP--EVLDTLSQLLKVK 445
             ++G   + +  IF +L+ IL+LGNV +    T R+      PP  E L     L+ V 
Sbjct: 312 CTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505
            E +   L  RK  T  +  I P S  +A  ARD++AK +Y+ LF+WIV  +N AL    
Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL---- 423

Query: 506 DVEEAVSCLS-IGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEG 564
               AV   S IGVLDI+GFE FE NSFEQFCINYANE+LQ  FN H+FKLEQEEY  E 
Sbjct: 424 --HSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481

Query: 565 ITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGT 624
           I W  I + DN  CI+LI  K  G+  LLDEE   P  T  T   K    H +       
Sbjct: 482 IPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540

Query: 625 P-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAV 682
           P +   AFIIQHFA KV+YQ + F EKN D +  + + +L+ S    + EL   D  A+
Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599



 Score =  149 bits (375), Expect = 4e-35
 Identities = 118/433 (27%), Positives = 205/433 (47%), Gaps = 25/433 (5%)

Query: 821  KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880
            K+   ++  QF+ SL+ L+E L    P ++RCI+ N  K    FD++  +QQLR  G+LE
Sbjct: 629  KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688

Query: 881  TVRIRRSGYSAKYTFQDFTEQFQVLL-PKDAQPCR-EVISTLLEKMKIDKRNYQIGKTKV 938
            T+RI  +G+ +++T+Q+F  +++VL+  KD    R +    +LEK+ +DK  YQ GKTK+
Sbjct: 689  TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748

Query: 939  FLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR-- 996
            F +  +   L++    ++    + +Q   R  L R+ +L+M++AA+T+Q   R Y+ R  
Sbjct: 749  FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808

Query: 997  -RALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE 1055
             + L RT+AA  +Q  WR Y  R+ Y+ ++ + I LQS  RG L R  + +++ E +   
Sbjct: 809  AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVI 868

Query: 1056 EKEREALEAARAGAEEGGQG----QAAGGQQVAEQGPEPAEDGG---------HLASEPE 1102
             ++R     AR   +         Q    + +A++  +  +            H+  E +
Sbjct: 869  IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928

Query: 1103 VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQ 1162
            +    R   E +   K+     + L   + +     EK+ S  E    R Q   E  K  
Sbjct: 929  IMQLQRKVDEQN---KDYKCLVEKLTNLEGIYNSETEKLRSDLE----RLQLSEEEAKVA 981

Query: 1163 NKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQP 1222
               + S +EE A        T+ +   + E     +++   LV   + ENT  KQ  E  
Sbjct: 982  TGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041

Query: 1223 QAMAVGKVSEETE 1235
                V +  E TE
Sbjct: 1042 NHRIVQQAKEMTE 1054



 Score = 48.1 bits (113), Expect = 9e-05
 Identities = 78/367 (21%), Positives = 154/367 (41%), Gaps = 50/367 (13%)

Query: 914  REVISTLLEK---MKIDKRNYQIGKTK-VFLKETERQALQETLHREVVR--KILLLQSWF 967
            R   +T+++K   M + +R Y+I +   + L+   R  L    +R+++R  K +++Q   
Sbjct: 814  RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873

Query: 968  RMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQS 1027
            R  L R H+ +   A + +Q C+R    +R L++ +        +     +KL+   +  
Sbjct: 874  RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-----KKLHIGMENK 928

Query: 1028 IIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAARAGAEEGGQGQAAGG 1080
            I++LQ   +   Q K +  ++ +    E       EK R  LE  +   EE    + A G
Sbjct: 929  IMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE---AKVATG 983

Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPL-EHSSPEKEAP-------SPEKTLPPQKT 1132
            + ++ Q     E+   L  + E   S++  + EH+   K+           E TL  Q+ 
Sbjct: 984  RVLSLQ-----EEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEK 1038

Query: 1133 VAAESHEKVPSSREKRESRRQRGLEHVKFQNKHI--QSCKEESALREPSRRVTQEQGVSL 1190
             A  +H  V  ++E  E+  ++ +E  K     +  +  + ++ L E SR          
Sbjct: 1039 EAL-NHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSR---------- 1087

Query: 1191 LEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETE-KTLPSGSPRPGQLE 1249
            LE++ +  ++E  L+V        +   T           SE  E + +PS +  P + +
Sbjct: 1088 LEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK 1147

Query: 1250 RPTSLAL 1256
             P  ++L
Sbjct: 1148 VPLDMSL 1154


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score =  381 bits (978), Expect = e-105
 Identities = 224/539 (41%), Positives = 307/539 (56%), Gaps = 16/539 (2%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207
           +DL  L  L E  +L NL+ RF+  K IYTY G +LVAINP++ LPIY    +  Y  Q 
Sbjct: 72  NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131

Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267
           +G ++PH+FA+A+ AY  M R   NQ I++SGESG+GKT S  + +     +S     + 
Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           VE  +L + P++E+ GNAKT  N+NSSRFGK+I++ + +   + GA +  YLLEKSR+V 
Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
           Q ++ERNYH+FY L       E +  +L   +++ Y  Q    + +G D   +    +QA
Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPP--EVLDTLSQLLKVK 445
             ++G   + +  IF +L+ IL+LGNV +    T R+      PP  E L     L+ V 
Sbjct: 312 CTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLCIFCDLMGVD 367

Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505
            E +   L  RK  T  +  I P S  +A  ARD++AK +Y+ LF+WIV  +N AL    
Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL---- 423

Query: 506 DVEEAVSCLS-IGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEG 564
               AV   S IGVLDI+GFE FE NSFEQFCINYANE+LQ  FN H+FKLEQEEY  E 
Sbjct: 424 --HSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481

Query: 565 ITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGT 624
           I W  I + DN  CI+LI  K  G+  LLDEE   P  T  T   K    H +       
Sbjct: 482 IPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540

Query: 625 P-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAV 682
           P +   AFIIQHFA KV+YQ + F EKN D +  + + +L+ S    + EL   D  A+
Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599



 Score =  149 bits (375), Expect = 4e-35
 Identities = 118/433 (27%), Positives = 205/433 (47%), Gaps = 25/433 (5%)

Query: 821  KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880
            K+   ++  QF+ SL+ L+E L    P ++RCI+ N  K    FD++  +QQLR  G+LE
Sbjct: 629  KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688

Query: 881  TVRIRRSGYSAKYTFQDFTEQFQVLL-PKDAQPCR-EVISTLLEKMKIDKRNYQIGKTKV 938
            T+RI  +G+ +++T+Q+F  +++VL+  KD    R +    +LEK+ +DK  YQ GKTK+
Sbjct: 689  TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748

Query: 939  FLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR-- 996
            F +  +   L++    ++    + +Q   R  L R+ +L+M++AA+T+Q   R Y+ R  
Sbjct: 749  FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808

Query: 997  -RALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE 1055
             + L RT+AA  +Q  WR Y  R+ Y+ ++ + I LQS  RG L R  + +++ E +   
Sbjct: 809  AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVI 868

Query: 1056 EKEREALEAARAGAEEGGQG----QAAGGQQVAEQGPEPAEDGG---------HLASEPE 1102
             ++R     AR   +         Q    + +A++  +  +            H+  E +
Sbjct: 869  IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928

Query: 1103 VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQ 1162
            +    R   E +   K+     + L   + +     EK+ S  E    R Q   E  K  
Sbjct: 929  IMQLQRKVDEQN---KDYKCLVEKLTNLEGIYNSETEKLRSDLE----RLQLSEEEAKVA 981

Query: 1163 NKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQP 1222
               + S +EE A        T+ +   + E     +++   LV   + ENT  KQ  E  
Sbjct: 982  TGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041

Query: 1223 QAMAVGKVSEETE 1235
                V +  E TE
Sbjct: 1042 NHRIVQQAKEMTE 1054



 Score = 48.1 bits (113), Expect = 9e-05
 Identities = 78/367 (21%), Positives = 154/367 (41%), Gaps = 50/367 (13%)

Query: 914  REVISTLLEK---MKIDKRNYQIGKTK-VFLKETERQALQETLHREVVR--KILLLQSWF 967
            R   +T+++K   M + +R Y+I +   + L+   R  L    +R+++R  K +++Q   
Sbjct: 814  RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873

Query: 968  RMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQS 1027
            R  L R H+ +   A + +Q C+R    +R L++ +        +     +KL+   +  
Sbjct: 874  RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-----KKLHIGMENK 928

Query: 1028 IIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAARAGAEEGGQGQAAGG 1080
            I++LQ   +   Q K +  ++ +    E       EK R  LE  +   EE    + A G
Sbjct: 929  IMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE---AKVATG 983

Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPL-EHSSPEKEAP-------SPEKTLPPQKT 1132
            + ++ Q     E+   L  + E   S++  + EH+   K+           E TL  Q+ 
Sbjct: 984  RVLSLQ-----EEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEK 1038

Query: 1133 VAAESHEKVPSSREKRESRRQRGLEHVKFQNKHI--QSCKEESALREPSRRVTQEQGVSL 1190
             A  +H  V  ++E  E+  ++ +E  K     +  +  + ++ L E SR          
Sbjct: 1039 EAL-NHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSR---------- 1087

Query: 1191 LEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETE-KTLPSGSPRPGQLE 1249
            LE++ +  ++E  L+V        +   T           SE  E + +PS +  P + +
Sbjct: 1088 LEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK 1147

Query: 1250 RPTSLAL 1256
             P  ++L
Sbjct: 1148 VPLDMSL 1154


>gi|153945715 myosin VC [Homo sapiens]
          Length = 1742

 Score =  379 bits (973), Expect = e-104
 Identities = 215/520 (41%), Positives = 304/520 (58%), Gaps = 10/520 (1%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207
           +DL  L  L E  +L NL+ RF + K IYTY+G ILVA+NP+K LPIY    +  Y  Q 
Sbjct: 70  NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129

Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267
           +G ++PH+FA+A+ AY  M R   NQ I++SGESG+GKT S  + +     +S+ G  + 
Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           VE  +L + P+ EA GNAKT  N+NSSRFGK+ ++S+ E   + GA +  YLLEKSR+V 
Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
           Q ++ERNYH+FY L     + E +  +L   E++ Y       + +G + + +    ++ 
Sbjct: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKRE 447
             ++GF    +  +F +L+AIL+LGNV  +  A G E          L    +LL ++  
Sbjct: 310 FTLLGFKEDFQMDVFKILAAILHLGNV--QITAVGNERSSVSEDDSHLKVFCELLGLESG 367

Query: 448 ILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDV 507
            + + L  RK VT ++ ++ P +  +A+ ARD++AK +Y+ LFD+IV RIN AL      
Sbjct: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422

Query: 508 EEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITW 567
                   IGVLDI+GFE F+ NSFEQFCINYANE+LQ  FN H+FKLEQEEY  E I W
Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482

Query: 568 HNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVM 627
             I + DN   I LI  K  G+  LLDEE   PH T +  L K      +       P M
Sbjct: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541

Query: 628 -EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGS 666
              +F+IQHFA KV+Y+ + F EKN D +   +V +LR S
Sbjct: 542 SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRAS 581



 Score =  134 bits (338), Expect = 7e-31
 Identities = 76/250 (30%), Positives = 139/250 (55%), Gaps = 9/250 (3%)

Query: 810  RTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELV 869
            ++ K ++  + K    ++ ++F++SL  L+E L    P ++RCI+ N EK    FD + +
Sbjct: 607  KSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRI 666

Query: 870  LQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDA---QPCREVISTLLEKMKI 926
            +QQLR  G+LET+RI    Y +++T+ +F  ++ +L+ K        +EV   +L ++  
Sbjct: 667  VQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQ 726

Query: 927  DKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTI 986
            D   YQ GKTK+F +  +   L++    ++ +  +++Q   R  L+R+ FL+ +RAA+ I
Sbjct: 727  DSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALII 786

Query: 987  QACWRSYRVRR------ALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQ 1040
            Q  +R  +  R      AL+   AA+ +Q   RGY  R LY+  + + I +Q+  RG L 
Sbjct: 787  QQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLA 846

Query: 1041 RKSFSQMISE 1050
            R+ + +M+ E
Sbjct: 847  RRRYRKMLEE 856


>gi|92859701 myosin VI [Homo sapiens]
          Length = 1285

 Score =  367 bits (943), Expect = e-101
 Identities = 220/572 (38%), Positives = 326/572 (56%), Gaps = 53/572 (9%)

Query: 147 DFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLP-IYNPKYVKMYEN 205
           D +D C+L  L E  LL N+K R+ + +IYTY  +IL+A+NP+  +P IY+ + +K Y+ 
Sbjct: 58  DVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQG 117

Query: 206 QQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYA 265
           + LG   PHVFA+AD A+  M   +++Q I++SGESG+GKT++T F++  LT     G  
Sbjct: 118 KSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT--ESYGTG 175

Query: 266 SGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRL 325
             ++  I+ A P+LEAFGNAKT  NNNSSRFGKF+++ + E   V G  V  YLLEKSR+
Sbjct: 176 QDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRI 235

Query: 326 VSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNL-----KIEDGEDLKH- 379
             Q K+ERNYH+FY L  G SE+ R++  L  P+++ YLN+        K  D + L++ 
Sbjct: 236 CVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNR 295

Query: 380 --------------------DFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR 419
                               DF R+  AM+ +G     K  +F V++ +L+LGN+ +++ 
Sbjct: 296 KSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEA 355

Query: 420 -ATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTV-----NDKLILPYSLSE 473
            +T     L+    + L+  ++LL + ++ L   LT R  +T         + +P  + +
Sbjct: 356 GSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQ 415

Query: 474 AITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFE 533
           A  ARD++AK++YS LFD +V R+N     +       S   IGVLDI GFE FE NSFE
Sbjct: 416 ANNARDALAKTVYSHLFDHVVNRVNQCFPFE------TSSYFIGVLDIAGFEYFEHNSFE 469

Query: 534 QFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLL 593
           QFCINY NE+LQ +FN+ I K EQE YQ EG+  + + Y DN  CI LI  K  G+  +L
Sbjct: 470 QFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDIL 529

Query: 594 DEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVM-----------EPAFIIQHFAGKVKY 642
           DEE+  P  + Q   +   Q+H+D+ + L  P             +  FII+HFAG V Y
Sbjct: 530 DEENRLPQPSDQHFTSAVHQKHKDH-FRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCY 588

Query: 643 QIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674
           +   F EKN D +   + +L+  S   ++REL
Sbjct: 589 ETTQFVEKNNDALHMSLESLICESRDKFIREL 620



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 82/405 (20%), Positives = 174/405 (42%), Gaps = 49/405 (12%)

Query: 826  SISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIR 885
            S+  +F+T LN LL+ L      FIRCI+ N +     F+   +L QL+ +GM+  + + 
Sbjct: 642  SVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLM 701

Query: 886  RSGYSAKYTFQDFTEQFQVLLPKDAQPC--REVISTLLEKMKIDKRNYQIGKTKVFLKET 943
            + GY ++ +F +    ++  +P        R     L + + +++ +Y+ G TKVF +  
Sbjct: 702  QGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPG 761

Query: 944  ERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRS-YRVRRALE-R 1001
            +     + +  +             +V    H+L   R    +Q C  S  +++  ++ R
Sbjct: 762  KFAEFDQIMKSDP-------DHLAELVKRVNHWLTCSRWK-KVQWCSLSVIKLKNKIKYR 813

Query: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREA 1061
             +A + +Q + R +  ++ ++ +   ++++ +L                 +K  +K  E 
Sbjct: 814  AEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTL-----------------KKRLDKFNEV 856

Query: 1062 LEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAP 1121
            +   + G  E         +Q+  +  E + D      +  +   ++   E+ +  K + 
Sbjct: 857  VSVLKDGKPE-------MNKQI--KNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSE 907

Query: 1122 SPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALR-EPSR 1180
                 L  +K    E+ E++   +E+ E  R+R  E  K + K     +EE  ++ E   
Sbjct: 908  ELLSALQKKKQQEEEA-ERLRRIQEEMEKERKRREEDEKRRRKE----EEERRMKLEMEA 962

Query: 1181 RVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAM 1225
            +  QE+     E++K+  +DE  +  E EA+   QK+   Q QA+
Sbjct: 963  KRKQEE-----EERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002


>gi|27544941 myosin IF [Homo sapiens]
          Length = 1098

 Score =  367 bits (942), Expect = e-101
 Identities = 209/544 (38%), Positives = 323/544 (59%), Gaps = 28/544 (5%)

Query: 144 QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMY 203
           +Q+  DD+  LP++TE  +  NL+ RF+   I+TY GS+L+++NPFK +P +  + + +Y
Sbjct: 15  KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74

Query: 204 ENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG 263
           +     +  PH++AL D  Y  ML    NQC++ISGESG+GKT +  +++  ++ +S  G
Sbjct: 75  QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGG 134

Query: 264 Y-ASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEK 322
                V+  IL + P+LEAFGNAKT  NNNSSRFGK+ ++ +   G   G  +  +LLEK
Sbjct: 135 EKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEK 194

Query: 323 SRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFE 382
           SR+V Q ++ERN+H++Y LL G S+E+RQ   L  P+ Y+YLNQ +    DG D + DF 
Sbjct: 195 SRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFG 254

Query: 383 RLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEG--LEVGPPEVLDTLSQ 440
               AM+++G  P+ ++ +  +++ IL+LGN+++       E+G    V   ++L   + 
Sbjct: 255 ETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF------CEDGNYARVESVDLLAFPAY 308

Query: 441 LLKVKREILVEVLTKRKTVT----VNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLR 496
           LL +    L E LT RK  +     ++ + +  ++ +A   RD++AK LY+ LFD++V  
Sbjct: 309 LLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEA 368

Query: 497 INHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLE 556
           IN A+  +K  EE     SIGVLDI+GFE F++N FEQFCIN+ NE+LQ  F +   K E
Sbjct: 369 INRAM--QKPQEE----YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAE 422

Query: 557 QEEYQGEGITWHNIGYTDNVGCIHLISKK--PTGLFYLLDEESNFPHAT----SQTLLAK 610
           QEEY  EGI W  I Y +N     LI  K  P G+  +LD+     HAT     QTLL K
Sbjct: 423 QEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQK 482

Query: 611 FKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSY 670
            +     +++F         F+I H+AGKV Y +  F E+N D +  D++ L++ S+ ++
Sbjct: 483 LQAAVGTHEHFNS---WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAF 539

Query: 671 VREL 674
           +R L
Sbjct: 540 LRML 543



 Score = 80.5 bits (197), Expect = 2e-14
 Identities = 52/194 (26%), Positives = 96/194 (49%), Gaps = 6/194 (3%)

Query: 820  KKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGML 879
            KK +P +  ++ +   N L+  L +  P +IRCI+ N  K+   +++  V  Q+ Y G+ 
Sbjct: 552  KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLK 611

Query: 880  ETVRIRRSGYSAKYTFQDFTEQFQVLLPKD----AQPCREVISTLLEKMKIDKRNYQIGK 935
            E +R+RR+G++ +  F  F +++ +L P+         R+ +  LL  + ++   YQ+G 
Sbjct: 612  ENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGS 671

Query: 936  TKVFLKETERQ-ALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYR 994
            TKVF+K  E    L+E   R+       +Q  +R  +  R + +M+  A  I    +  R
Sbjct: 672  TKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNI-LLNKKER 730

Query: 995  VRRALERTQAAVYL 1008
             R ++ R     YL
Sbjct: 731  RRNSINRNFVGDYL 744


>gi|194328685 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  363 bits (932), Expect = e-99
 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%)

Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209
           D+  L  L E   + NLK RF   +IYTY GS+++++NP++ LPIY+P+ V+ Y N+   
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268
           +L PH+FAL+D AY ++  +  +QCI+I+GESG+GKT+++  ++  + A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           +  +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G   G V+  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
            + ERN+HVFY LL G SEE   + +L++    Y YL+  + K+ +G D   +F  ++ A
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445
           M++VGF+    + + AV++A+L LGN+ +K   R  G +E  ++     L  + +L  + 
Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316

Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505
           + +L    + R      +K+    ++++A  ARD++AK+LYS LF W+V RIN ++  + 
Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376

Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565
            V + V    +GVLDI+GFE FE NSFEQF INY NE+LQ  F +   K EQEEY  E I
Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432

Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617
            W +I Y +N     LI     G+  +LDEE   P   T +T L K  Q     QH +  
Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492

Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673
               +++   T +    F IQH+AGKV YQ++ F +KN D +  D+   +  +  + ++ 
Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552

Query: 674 L 674
           L
Sbjct: 553 L 553



 Score =  118 bits (295), Expect = 7e-26
 Identities = 73/253 (28%), Positives = 138/253 (54%), Gaps = 15/253 (5%)

Query: 822  KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881
            K+PP+  +QF+ S+  L++ L    P +IRCI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 882  VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937
            VR+RR+GY+ +  ++   E++++L     P    P R  +  L  +++I    Y  G++K
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 938  VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
            +F++        E L ++ +  +  L+Q  +R    R HFL MK++ + I A +R Y  +
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 997  RALERTQ-AAVYLQASWRGYWQRKLYR---HQ---KQSIIRLQSLCRGHLQRKSFSQMIS 1049
            +  ++T+ +A+ +Q+  RG+  RK+ R   HQ   K+++  + +   G   R+   ++  
Sbjct: 745  KRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRL-- 802

Query: 1050 EKQKAEEKEREAL 1062
             K++A  K   A+
Sbjct: 803  -KEEARNKHAIAV 814


>gi|44889481 myosin IB isoform 2 [Homo sapiens]
          Length = 1078

 Score =  363 bits (932), Expect = e-99
 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%)

Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209
           D+  L  L E   + NLK RF   +IYTY GS+++++NP++ LPIY+P+ V+ Y N+   
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268
           +L PH+FAL+D AY ++  +  +QCI+I+GESG+GKT+++  ++  + A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           +  +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G   G V+  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
            + ERN+HVFY LL G SEE   + +L++    Y YL+  + K+ +G D   +F  ++ A
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445
           M++VGF+    + + AV++A+L LGN+ +K   R  G +E  ++     L  + +L  + 
Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316

Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505
           + +L    + R      +K+    ++++A  ARD++AK+LYS LF W+V RIN ++  + 
Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376

Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565
            V + V    +GVLDI+GFE FE NSFEQF INY NE+LQ  F +   K EQEEY  E I
Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432

Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617
            W +I Y +N     LI     G+  +LDEE   P   T +T L K  Q     QH +  
Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492

Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673
               +++   T +    F IQH+AGKV YQ++ F +KN D +  D+   +  +  + ++ 
Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552

Query: 674 L 674
           L
Sbjct: 553 L 553



 Score =  117 bits (293), Expect = 1e-25
 Identities = 67/214 (31%), Positives = 122/214 (57%), Gaps = 9/214 (4%)

Query: 822  KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881
            K+PP+  +QF+ S+  L++ L    P +IRCI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 882  VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937
            VR+RR+GY+ +  ++   E++++L     P    P R  +  L  +++I    Y  G++K
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 938  VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
            +F++        E L ++ +  +  L+Q  +R    R HFL MK++ + I A +R Y  +
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 997  RALERTQ-AAVYLQASWRGYWQRKLYR---HQKQ 1026
            +  ++T+ +A+ +Q+  RG+  RK+ R   HQK+
Sbjct: 745  KRYQQTKSSALVIQSYIRGWKARKILRELKHQKR 778


>gi|240120050 myosin IB isoform 1 [Homo sapiens]
          Length = 1136

 Score =  363 bits (932), Expect = e-99
 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%)

Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209
           D+  L  L E   + NLK RF   +IYTY GS+++++NP++ LPIY+P+ V+ Y N+   
Sbjct: 19  DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78

Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268
           +L PH+FAL+D AY ++  +  +QCI+I+GESG+GKT+++  ++  + A+  KG   + V
Sbjct: 79  ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138

Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328
           +  +L + PVLEAFGNAKT  N+NSSRFGK++ + +   G   G V+  YLLEKSR+V Q
Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198

Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387
            + ERN+HVFY LL G SEE   + +L++    Y YL+  + K+ +G D   +F  ++ A
Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257

Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445
           M++VGF+    + + AV++A+L LGN+ +K   R  G +E  ++     L  + +L  + 
Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316

Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505
           + +L    + R      +K+    ++++A  ARD++AK+LYS LF W+V RIN ++  + 
Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376

Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565
            V + V    +GVLDI+GFE FE NSFEQF INY NE+LQ  F +   K EQEEY  E I
Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432

Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617
            W +I Y +N     LI     G+  +LDEE   P   T +T L K  Q     QH +  
Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492

Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673
               +++   T +    F IQH+AGKV YQ++ F +KN D +  D+   +  +  + ++ 
Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552

Query: 674 L 674
           L
Sbjct: 553 L 553



 Score =  118 bits (295), Expect = 7e-26
 Identities = 73/253 (28%), Positives = 138/253 (54%), Gaps = 15/253 (5%)

Query: 822  KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881
            K+PP+  +QF+ S+  L++ L    P +IRCI+ N +K    F++ LV  Q+RY G+LE 
Sbjct: 565  KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624

Query: 882  VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937
            VR+RR+GY+ +  ++   E++++L     P    P R  +  L  +++I    Y  G++K
Sbjct: 625  VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684

Query: 938  VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
            +F++        E L ++ +  +  L+Q  +R    R HFL MK++ + I A +R Y  +
Sbjct: 685  IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744

Query: 997  RALERTQ-AAVYLQASWRGYWQRKLYR---HQ---KQSIIRLQSLCRGHLQRKSFSQMIS 1049
            +  ++T+ +A+ +Q+  RG+  RK+ R   HQ   K+++  + +   G   R+   ++  
Sbjct: 745  KRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRL-- 802

Query: 1050 EKQKAEEKEREAL 1062
             K++A  K   A+
Sbjct: 803  -KEEARNKHAIAV 814


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score =  361 bits (927), Expect = 4e-99
 Identities = 223/588 (37%), Positives = 331/588 (56%), Gaps = 26/588 (4%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NLK R+    IYTY+G   V INP+K LPIY+ + V+
Sbjct: 77  PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTN----FLIHCLT 257
           MY+ ++  ++ PH++A+ D AY +M++ R +Q I+ +GESG+GKT++T     +L +  +
Sbjct: 137 MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196

Query: 258 ALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEK 317
           +   K     +ER +L A P+LEAFGNAKT  N+NSSRFGKFI++++  +G + GA +E 
Sbjct: 197 SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256

Query: 318 YLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDL 377
           YLLEKSR + Q K+ER +H+FYYLL G  E  + +  L+    Y +L+  ++ I   +D 
Sbjct: 257 YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQD- 315

Query: 378 KHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDT 437
           K  F+   +AM ++G     +  +  V+S +L LGN+ +KK     +  +          
Sbjct: 316 KDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMP--DNTAAQK 373

Query: 438 LSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLR 496
           +S LL +   +    +LT R  V   D +    +  +A  A +++AK+ Y  +F W+VLR
Sbjct: 374 VSHLLGINVTDFTRGILTPRIKVG-RDYVQKAQTKEQADFAIEALAKATYERMFRWLVLR 432

Query: 497 INHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLE 556
           IN AL    D  +      IG+LDI GFE F+ NSFEQ CINY NE+LQ  FN  +F LE
Sbjct: 433 INKAL----DKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILE 488

Query: 557 QEEYQGEGITWHNIGY-TDNVGCIHLISKK--PTGLFYLLDEESNFPHATSQTLLAKFKQ 613
           QEEYQ EGI W+ I +  D   CI LI K   P G+  LLDEE  FP AT ++ + K  Q
Sbjct: 489 QEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQ 548

Query: 614 QHEDNKYFLGTPVMEPA--FIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYV 671
           +   +  F     ++    F I H+AGKV Y+  ++  KNMD +  +I  LL  S   +V
Sbjct: 549 EQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFV 608

Query: 672 REL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
            EL       IG+D VA      L  A +    + R  G+L  E+  K
Sbjct: 609 SELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAK 656



 Score =  101 bits (251), Expect = 9e-21
 Identities = 94/420 (22%), Positives = 183/420 (43%), Gaps = 57/420 (13%)

Query: 826  SISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIR 885
            ++   ++  L KL+  L    P F+RCI  N EKK    D  LVL QLR  G+LE +RI 
Sbjct: 645  TVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRIC 704

Query: 886  RSGYSAKYTFQDFTEQFQVL----LPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLK 941
            R G+  +  FQ+F +++++L    +PK     ++    +++ +++D   Y+IG++KVF +
Sbjct: 705  RQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFR 764

Query: 942  ETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER 1001
                  L+E    ++   I+  Q+  R  L R+ F + ++    +          + L+R
Sbjct: 765  AGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAM----------KVLQR 814

Query: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREA 1061
              AA     +W+ +W  +L+   K  +          + R+    M  E++  + +E++ 
Sbjct: 815  NCAAYLKLRNWQ-WW--RLFTKVKPLL---------QVSRQEEEMMAKEEELVKVREKQL 862

Query: 1062 LEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAP 1121
                R    E  Q Q                    +A + ++Q       E    E E  
Sbjct: 863  AAENRLTEMETLQSQL-------------------MAEKLQLQ-------EQLQAETELC 896

Query: 1122 SPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNK----HIQSCKEESALRE 1177
            +  + L  + T   +  E++    E R    +   +H++ + K    +IQ  +E+    E
Sbjct: 897  AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956

Query: 1178 PSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237
             +R+  Q + V+  E K +  E+E +++ +   +   +K+  E   A     ++EE EK+
Sbjct: 957  SARQKLQLEKVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015



 Score = 34.3 bits (77), Expect = 1.4
 Identities = 39/173 (22%), Positives = 75/173 (43%), Gaps = 7/173 (4%)

Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEK---EREALEAARAGAEEGGQGQAAGGQQVAEQGP 1088
            QS C    ++K F Q+++E++    K   ER+  EA     E      A   ++  EQ  
Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493

Query: 1089 EPAEDGGHLASEPEVQPSDRSPLEHS--SPEKEAPSPEKTLPPQKTVAAESHEKVPSSRE 1146
            E         +E E   S +  +  S    EK   + E+ +   KT   E  +++ ++ E
Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQAT-E 1552

Query: 1147 KRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSL-LEDKKESR 1198
              + R +  L+ +K Q +     ++E +  +  + V Q + +   LED+++ R
Sbjct: 1553 DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score =  354 bits (908), Expect = 6e-97
 Identities = 218/591 (36%), Positives = 331/591 (56%), Gaps = 29/591 (4%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NL+ R+    IYTY+G   V +NP+K LPIY+ K V 
Sbjct: 81  PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259
           MY+ ++  ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T  +I  L   A 
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314
           S KG         +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++++  +G + GA 
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374
           +E YLLEKSR + Q +DER +H+FYY++ G  E+ R +  L+   +Y +L+   + I   
Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320

Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV 434
           +D    F+   +AM ++GF    +  I  V+S++L LGN+ +KK     +  +       
Sbjct: 321 QD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMP--DNTA 377

Query: 435 LDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWI 493
              +  L+ +   +    +LT R  V   D +    +  +A  A +++AK+ Y  LF WI
Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATYERLFRWI 436

Query: 494 VLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIF 553
           + R+N AL    D         +G+LDI GFE FE NSFEQ CINY NE+LQ  FN  +F
Sbjct: 437 LTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMF 492

Query: 554 KLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLLAK 610
            LEQEEYQ EGI W+ I +  D   CI LI +   P G+  LLDEE  FP AT ++ + K
Sbjct: 493 ILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEK 552

Query: 611 FKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDS 668
              +   +  F     +  +  F I H+AGKV Y    +  KNMD +  ++ +LL  S  
Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612

Query: 669 SYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
            +V +L       +G+D +A    + L +A +    + R  G+L  E+  K
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 663



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%)

Query: 797  KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853
            K +  I+ +    + T+S L    K K     ++   ++  L KL+  L    P F+RCI
Sbjct: 620  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 854  RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909
              N EK+    D  LVL+QLR  G+LE +RI R G+  +  FQ+F +++++L    +PK 
Sbjct: 680  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739

Query: 910  AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969
                ++    +++ +++D   Y+IG++K+F +      L+E    ++   I+  Q+  R 
Sbjct: 740  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799

Query: 970  VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013
             L R+ F + ++    ++                 WR + +V+  L+ T+    +QA  +
Sbjct: 800  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 857

Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066
                +K    Q+++   L+ L + H Q      ++ E+ +AE       E+ R  L A +
Sbjct: 858  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917

Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119
               EE         + +   GQQ+  +  + A+    L  + E + + R  L+      E
Sbjct: 918  QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977

Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179
            A    K L  +  V  + + K+   R+  E R      ++  +    +  K  + L+   
Sbjct: 978  AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1032

Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234
              +  E  V L +++K  +E E L   +E +A +  ++    Q Q     M + K  EE 
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092

Query: 1235 EKTL 1238
            +  L
Sbjct: 1093 QAAL 1096


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score =  354 bits (908), Expect = 6e-97
 Identities = 218/591 (36%), Positives = 331/591 (56%), Gaps = 29/591 (4%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NL+ R+    IYTY+G   V +NP+K LPIY+ K V 
Sbjct: 81  PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259
           MY+ ++  ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T  +I  L   A 
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314
           S KG         +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++++  +G + GA 
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374
           +E YLLEKSR + Q +DER +H+FYY++ G  E+ R +  L+   +Y +L+   + I   
Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320

Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV 434
           +D    F+   +AM ++GF    +  I  V+S++L LGN+ +KK     +  +       
Sbjct: 321 QD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMP--DNTA 377

Query: 435 LDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWI 493
              +  L+ +   +    +LT R  V   D +    +  +A  A +++AK+ Y  LF WI
Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATYERLFRWI 436

Query: 494 VLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIF 553
           + R+N AL    D         +G+LDI GFE FE NSFEQ CINY NE+LQ  FN  +F
Sbjct: 437 LTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMF 492

Query: 554 KLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLLAK 610
            LEQEEYQ EGI W+ I +  D   CI LI +   P G+  LLDEE  FP AT ++ + K
Sbjct: 493 ILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEK 552

Query: 611 FKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDS 668
              +   +  F     +  +  F I H+AGKV Y    +  KNMD +  ++ +LL  S  
Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612

Query: 669 SYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
            +V +L       +G+D +A    + L +A +    + R  G+L  E+  K
Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 663



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%)

Query: 797  KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853
            K +  I+ +    + T+S L    K K     ++   ++  L KL+  L    P F+RCI
Sbjct: 620  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679

Query: 854  RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909
              N EK+    D  LVL+QLR  G+LE +RI R G+  +  FQ+F +++++L    +PK 
Sbjct: 680  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739

Query: 910  AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969
                ++    +++ +++D   Y+IG++K+F +      L+E    ++   I+  Q+  R 
Sbjct: 740  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799

Query: 970  VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013
             L R+ F + ++    ++                 WR + +V+  L+ T+    +QA  +
Sbjct: 800  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 857

Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066
                +K    Q+++   L+ L + H Q      ++ E+ +AE       E+ R  L A +
Sbjct: 858  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917

Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119
               EE         + +   GQQ+  +  + A+    L  + E + + R  L+      E
Sbjct: 918  QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977

Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179
            A    K L  +  V  + + K+   R+  E R      ++  +    +  K  + L+   
Sbjct: 978  AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1032

Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234
              +  E  V L +++K  +E E L   +E +A +  ++    Q Q     M + K  EE 
Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092

Query: 1235 EKTL 1238
            +  L
Sbjct: 1093 QAAL 1096


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score =  353 bits (907), Expect = 8e-97
 Identities = 227/593 (38%), Positives = 330/593 (55%), Gaps = 33/593 (5%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NLK R+    IYTY+G   V INP+K LPIY+   ++
Sbjct: 81  PPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIE 140

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259
           MY  ++  ++ PH++A+++ AY  ML+ R +Q I+ +GESG+GKT++T  +I  L   A 
Sbjct: 141 MYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS 200

Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314
           S KG         +ER +L A P+LE+FGNAKT  N+NSSRFGKFI++++  +G + GA 
Sbjct: 201 SHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260

Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374
           +E YLLEKSR V Q KDER +H+FY LL G  E  + +  L+   +Y +L+   + I   
Sbjct: 261 IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQ 320

Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPE- 433
           +D K +F+   +AM ++GF       +  V+S++L  GN+++KK     +  +    PE 
Sbjct: 321 QD-KDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM----PEN 375

Query: 434 -VLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFD 491
            V   L  LL +   E    +LT R  V   D +    +  +A  A +++AK+ Y  LF 
Sbjct: 376 TVAQKLCHLLGMNVMEFTRAILTPRIKVG-RDYVQKAQTKEQADFAVEALAKATYERLFR 434

Query: 492 WIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQH 551
           W+V RIN AL    D  +      IG+LDI GFE FE NSFEQ CINY NE+LQ  FN  
Sbjct: 435 WLVHRINKAL----DRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHT 490

Query: 552 IFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLL 608
           +F LEQEEYQ EGI W+ I +  D   CI LI +   P G+  LLDEE  FP AT +T +
Sbjct: 491 MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFV 550

Query: 609 AKFKQQHEDNKYFLGTPVMEPA--FIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGS 666
            K  Q+   +  F     ++    F I H+AGKV Y+  ++  KNMD +  ++  LL  S
Sbjct: 551 EKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQS 610

Query: 667 DSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
              +V EL       +G+D V         +A +    + R  G+L  E   K
Sbjct: 611 SDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTK 663



 Score =  106 bits (264), Expect = 3e-22
 Identities = 107/422 (25%), Positives = 180/422 (42%), Gaps = 51/422 (12%)

Query: 820  KKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGML 879
            KK    ++   ++ SL KL+  L    P F+RCI  N EK+    D  LVL QLR  G+L
Sbjct: 646  KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705

Query: 880  ETVRIRRSGYSAKYTFQDFTEQFQVL----LPKDAQPCREVISTLLEKMKIDKRNYQIGK 935
            E +RI R G+  +  FQ+F +++++L    +PK     ++    ++  +++D   Y+IG+
Sbjct: 706  EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765

Query: 936  TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995
            +K+F +      L+E    ++   I+  Q+  R  L R+ F + ++    +         
Sbjct: 766  SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSAL--------- 816

Query: 996  RRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM-ISEKQKA 1054
             + L+R  AA      W+  W R   + +    +  Q      LQ K    + + EKQ  
Sbjct: 817  -KVLQRNCAAYLKLRHWQ--WWRVFTKVKPLLQVTRQ---EEELQAKDEELLKVKEKQTK 870

Query: 1055 EEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHS 1114
             E E E +E                 QQ+ E+    AE    L +E E+           
Sbjct: 871  VEGELEEMERKH--------------QQLLEEKNILAE---QLQAETEL----------- 902

Query: 1115 SPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESA 1174
                EA      L  +K    E    + S  E+ E R Q      K    HIQ  +E+  
Sbjct: 903  --FAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960

Query: 1175 LREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEET 1234
              E +R+  Q + V+  E K +  E+E LL+ +  ++   +K+  E   A    +++EE 
Sbjct: 961  EEEGARQKLQLEKVT-AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019

Query: 1235 EK 1236
            EK
Sbjct: 1020 EK 1021


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score =  352 bits (904), Expect = 2e-96
 Identities = 220/598 (36%), Positives = 334/598 (55%), Gaps = 36/598 (6%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NL+ R+    IYTY+G   V +NP+K LPIY+ K V 
Sbjct: 81  PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259
           MY+ ++  ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T  +I  L   A 
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 260 SQKG-----------YASG-VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLES 307
           S KG           +A G +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++++  +
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 308 GIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQH 367
           G + GA +E YLLEKSR + Q +DER +H+FYY++ G  E+ R +  L+   +Y +L+  
Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 368 NLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGL 427
            + I   +D    F+   +AM ++GF    +  I  V+S++L LGN+ +KK     +  +
Sbjct: 321 FVPIPAAQD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM 379

Query: 428 EVGPPEVLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLY 486
                     +  L+ +   +    +LT R  V   D +    +  +A  A +++AK+ Y
Sbjct: 380 P--DNTAAQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATY 436

Query: 487 SALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQY 546
             LF WI+ R+N AL    D         +G+LDI GFE FE NSFEQ CINY NE+LQ 
Sbjct: 437 ERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 492

Query: 547 YFNQHIFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHAT 603
            FN  +F LEQEEYQ EGI W+ I +  D   CI LI +   P G+  LLDEE  FP AT
Sbjct: 493 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT 552

Query: 604 SQTLLAKFKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVA 661
            ++ + K   +   +  F     +  +  F I H+AGKV Y    +  KNMD +  ++ +
Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612

Query: 662 LLRGSDSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
           LL  S   +V +L       +G+D +A    + L +A +    + R  G+L  E+  K
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%)

Query: 797  KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853
            K +  I+ +    + T+S L    K K     ++   ++  L KL+  L    P F+RCI
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686

Query: 854  RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909
              N EK+    D  LVL+QLR  G+LE +RI R G+  +  FQ+F +++++L    +PK 
Sbjct: 687  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746

Query: 910  AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969
                ++    +++ +++D   Y+IG++K+F +      L+E    ++   I+  Q+  R 
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 970  VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013
             L R+ F + ++    ++                 WR + +V+  L+ T+    +QA  +
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 864

Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066
                +K    Q+++   L+ L + H Q      ++ E+ +AE       E+ R  L A +
Sbjct: 865  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924

Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119
               EE         + +   GQQ+  +  + A+    L  + E + + R  L+      E
Sbjct: 925  QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984

Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179
            A    K L  +  V  + + K+   R+  E R      ++  +    +  K  + L+   
Sbjct: 985  AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1039

Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234
              +  E  V L +++K  +E E L   +E +A +  ++    Q Q     M + K  EE 
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099

Query: 1235 EKTL 1238
            +  L
Sbjct: 1100 QAAL 1103


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score =  352 bits (904), Expect = 2e-96
 Identities = 220/598 (36%), Positives = 334/598 (55%), Gaps = 36/598 (6%)

Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201
           P + +  +D+  L  L E ++L NL+ R+    IYTY+G   V +NP+K LPIY+ K V 
Sbjct: 81  PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140

Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259
           MY+ ++  ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T  +I  L   A 
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200

Query: 260 SQKG-----------YASG-VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLES 307
           S KG           +A G +E+ +L A P+LEAFGNAKT  N+NSSRFGKFI++++  +
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260

Query: 308 GIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQH 367
           G + GA +E YLLEKSR + Q +DER +H+FYY++ G  E+ R +  L+   +Y +L+  
Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320

Query: 368 NLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGL 427
            + I   +D    F+   +AM ++GF    +  I  V+S++L LGN+ +KK     +  +
Sbjct: 321 FVPIPAAQD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM 379

Query: 428 EVGPPEVLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLY 486
                     +  L+ +   +    +LT R  V   D +    +  +A  A +++AK+ Y
Sbjct: 380 P--DNTAAQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATY 436

Query: 487 SALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQY 546
             LF WI+ R+N AL    D         +G+LDI GFE FE NSFEQ CINY NE+LQ 
Sbjct: 437 ERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 492

Query: 547 YFNQHIFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHAT 603
            FN  +F LEQEEYQ EGI W+ I +  D   CI LI +   P G+  LLDEE  FP AT
Sbjct: 493 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT 552

Query: 604 SQTLLAKFKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVA 661
            ++ + K   +   +  F     +  +  F I H+AGKV Y    +  KNMD +  ++ +
Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612

Query: 662 LLRGSDSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711
           LL  S   +V +L       +G+D +A    + L +A +    + R  G+L  E+  K
Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670



 Score = 97.1 bits (240), Expect = 2e-19
 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%)

Query: 797  KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853
            K +  I+ +    + T+S L    K K     ++   ++  L KL+  L    P F+RCI
Sbjct: 627  KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686

Query: 854  RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909
              N EK+    D  LVL+QLR  G+LE +RI R G+  +  FQ+F +++++L    +PK 
Sbjct: 687  IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746

Query: 910  AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969
                ++    +++ +++D   Y+IG++K+F +      L+E    ++   I+  Q+  R 
Sbjct: 747  FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806

Query: 970  VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013
             L R+ F + ++    ++                 WR + +V+  L+ T+    +QA  +
Sbjct: 807  YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 864

Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066
                +K    Q+++   L+ L + H Q      ++ E+ +AE       E+ R  L A +
Sbjct: 865  EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924

Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119
               EE         + +   GQQ+  +  + A+    L  + E + + R  L+      E
Sbjct: 925  QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984

Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179
            A    K L  +  V  + + K+   R+  E R      ++  +    +  K  + L+   
Sbjct: 985  AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1039

Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234
              +  E  V L +++K  +E E L   +E +A +  ++    Q Q     M + K  EE 
Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099

Query: 1235 EKTL 1238
            +  L
Sbjct: 1100 QAAL 1103


>gi|4885503 myosin IA [Homo sapiens]
          Length = 1043

 Score =  351 bits (900), Expect = 5e-96
 Identities = 209/547 (38%), Positives = 310/547 (56%), Gaps = 32/547 (5%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           +DL  L  L E +LLKNL+ R+  ++IYTY G++++++NP++ LPIY P+++  Y++   
Sbjct: 11  EDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYTF 70

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASG 267
            +L+PH++ALA+VAY ++  +  +QCI+I+GESGSGKT+++  ++  + A+  KG   + 
Sbjct: 71  YELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQVNS 130

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           V+  +L + PVLEAFGNAKT  NNNSSRFGK++ + +   G   G V+  YLLEKSRLV 
Sbjct: 131 VKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRLVK 190

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQL-KQPEDYFYLNQHNLKIEDGEDLKHDFERLKQ 386
           Q K ERN+H+FY LL G  E+  +  +L +    Y YLN H +   DG D    F  ++ 
Sbjct: 191 QLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLN-HEVSRVDGMDDASSFRAVQS 249

Query: 387 AMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR-------ATGREEGLEVGPPEVLDTLS 439
           AM ++GF     +Q+  V S +L LGNV            A+G  +G  V        + 
Sbjct: 250 AMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGV------REIG 303

Query: 440 QLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINH 499
           +++ +  E +   L  R   T  +K++   ++ +A  ARD++AK++YS LFDWIV RIN 
Sbjct: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363

Query: 500 ALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEE 559
           ++  K  + E    +  GVLDI+GFE  E NSFEQF INY NE+LQ  F +   K EQEE
Sbjct: 364 SI--KVGIGEKKKVM--GVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEE 419

Query: 560 YQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATS-QTLLAKFKQQHEDN 618
           Y+ EGI W  + Y DN     LI     G+  +LDEE   P   S  T LAK  Q    +
Sbjct: 420 YKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKH 479

Query: 619 KYFLGTPVME-----------PAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSD 667
            ++                    F I H+AGKV Y +  F +KN D +  D++  +  + 
Sbjct: 480 GHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539

Query: 668 SSYVREL 674
              +R L
Sbjct: 540 HPLLRSL 546



 Score =  104 bits (260), Expect = 8e-22
 Identities = 69/229 (30%), Positives = 118/229 (51%), Gaps = 29/229 (12%)

Query: 822  KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881
            K+PP+  AQF++S+  L++ L    P +IRCI+ N  ++   F  +LV  Q RY G+LE 
Sbjct: 558  KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLEN 617

Query: 882  VRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPC-----REVISTLLEKMKIDKRNYQIGKT 936
            VR+RR+GY+ +  +  F E+++ LL +   P      RE +  +L ++ +       GKT
Sbjct: 618  VRVRRAGYAHRQGYGPFLERYR-LLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKT 676

Query: 937  KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996
            K+F++  +      TL                  LE +  L++++ A  IQ  +R +R R
Sbjct: 677  KIFIRSPK------TL----------------FYLEEQRRLRLQQLATLIQKIYRGWRCR 714

Query: 997  RALERTQAAVYLQASW-RGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF 1044
               +  + +  L +SW RG  Q+K Y   K S++ +Q+  RG   RK++
Sbjct: 715  THYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNY 763


>gi|55956916 myosin IE [Homo sapiens]
          Length = 1108

 Score =  350 bits (899), Expect = 7e-96
 Identities = 199/538 (36%), Positives = 321/538 (59%), Gaps = 26/538 (4%)

Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208
           DD+  L ++TE ++++NLK R++   I+TY GS+L+++NPFK +P +  K ++MY+    
Sbjct: 22  DDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQ 81

Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGY-ASG 267
            +  PH++ALAD  Y  M+  R NQC++ISGESG+GKT +  +++  ++ +S  G     
Sbjct: 82  YENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKVQH 141

Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327
           V+  IL + P+LEAFGNAKT  NNNSSRFGK+ ++ +   G   G  +  +LLEKSR+V 
Sbjct: 142 VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVM 201

Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLN-QHNLKIEDGEDLKHDFERLKQ 386
           +   ER++H+FY L+ G S E++    +   + Y+YL+   + K++D +D + +F+    
Sbjct: 202 RNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDD-RREFQETLH 260

Query: 387 AMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKR 446
           AM ++G     +  +  +++ IL+LGN+++K+   G    +E    E L   + LL + +
Sbjct: 261 AMNVIGIFAEEQTLVLQIVAGILHLGNISFKE--VGNYAAVE--SEEFLAFPAYLLGINQ 316

Query: 447 EILVEVLTKR----KTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502
           + L E LT R    K    ++ + +  ++ +A   RD++AK+L++ +FD++V  IN A+ 
Sbjct: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM- 375

Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562
            +KD EE     +IGVLDI+GFE F++N FEQFCIN+ NE+LQ  F +   K EQEEY  
Sbjct: 376 -EKDHEE----YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQ 430

Query: 563 EGITWHNIGYTDNVGCIHLISKK--PTGLFYLLDEESNFPHA----TSQTLLAKFKQQHE 616
           EGI W  I Y +N     LI  K  P G+  +LD+     HA      QTLL K + Q  
Sbjct: 431 EGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIG 490

Query: 617 DNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674
            +++F         FII H+AGKV Y +  F E+N D +  D++ L++ S+  +++ L
Sbjct: 491 SHEHFNS---WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSL 545



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 50/173 (28%), Positives = 93/173 (53%), Gaps = 5/173 (2%)

Query: 816 LHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRY 875
           L   KK +P +  ++ +   N L+  L K  P +IRCI+ N  KK   +++  V  Q+ Y
Sbjct: 550 LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEY 609

Query: 876 TGMLETVRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNY 931
            G+ E +R+RR+GY+ +  FQ F +++ +L     P      ++ +  LL+ + +D   +
Sbjct: 610 LGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQF 669

Query: 932 QIGKTKVFLKETERQ-ALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAA 983
           Q+G++KVF+K  E    L+E   R+      ++Q  +R  + R+ ++QM+  A
Sbjct: 670 QLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEA 722


>gi|124494238 myosin IC isoform a [Homo sapiens]
          Length = 1063

 Score =  341 bits (874), Expect = 5e-93
 Identities = 203/557 (36%), Positives = 313/557 (56%), Gaps = 23/557 (4%)

Query: 118 IKYVH----MQLVAQATATRRLVERGLLPRQQADFDDLCNLPELT-EGNLLKNLKHRFLQ 172
           I+ VH     +L   +   R  +E  L  R +    D   L   T E   ++NL+ RF +
Sbjct: 14  IRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRE 73

Query: 173 QKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVN 232
             IYTY G +LV++NP++ L IY+ ++++ Y      ++ PH+FA+AD  Y  +  +R +
Sbjct: 74  NLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRD 133

Query: 233 QCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERT-ILGAGPVLEAFGNAKTAHNN 291
           Q ++ISGESG+GKT++T  L+             G  R  +L + PVLEAFGNAKT  N+
Sbjct: 134 QAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRND 193

Query: 292 NSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQ 351
           NSSRFGK++ V +   G   G  +  YLLEKSR+V Q   ERN+H+FY LL G  EE  +
Sbjct: 194 NSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLR 253

Query: 352 EFQLKQ-PEDYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILY 410
              L++ P+ Y YL +         + K D++ +++A+ ++ F     + + ++++++L+
Sbjct: 254 RLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLH 313

Query: 411 LGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYS 470
           LGN+ +   A   E   +V     L  L++LL V+   L E LT RK +   ++L+ P +
Sbjct: 314 LGNIHF---AANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLN 370

Query: 471 LSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAV--SCLSIGVLDIFGFEDFE 528
           L +A  ARD++AK++YS  F W+V +IN +L +K DVE     S   +G+LDI+GFE F+
Sbjct: 371 LEQAAYARDALAKAVYSRTFTWLVGKINRSLASK-DVESPSWRSTTVLGLLDIYGFEVFQ 429

Query: 529 RNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTG 588
            NSFEQFCINY NE+LQ  F +   K EQEEY+ EGI W  + Y +N     L+ +K  G
Sbjct: 430 HNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKG 489

Query: 589 LFYLLDEESNFP-HATSQTLLAKFKQQHEDNKYFLGTPVMEP---------AFIIQHFAG 638
           +  +LDEE   P  AT  T L K +   + + +FL   + +           F + H+AG
Sbjct: 490 IISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAG 549

Query: 639 KVKYQIKDFREKNMDYM 655
           +V Y +  F +KN D +
Sbjct: 550 EVTYSVTGFLDKNNDLL 566



 Score =  106 bits (265), Expect = 2e-22
 Identities = 74/241 (30%), Positives = 138/241 (57%), Gaps = 16/241 (6%)

Query: 784  KQKQIIPKNLLDSK-SLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEAL 842
            K   ++ +NL ++  S K  I     DR+      L  KK+P +++ QF+ SL +L+E L
Sbjct: 561  KNNDLLFRNLKETMCSSKNPIMSQCFDRS-----ELSDKKRPETVATQFKMSLLQLVEIL 615

Query: 843  GKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQF 902
               EP ++RCI+ N  K+   FD+ L+  Q++Y G+LE +R+RR+G++ +  ++ F +++
Sbjct: 616  QSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRY 675

Query: 903  QVLLPKD----AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQ-ALQETLHREVV 957
            + L P+     A   ++ ++ L+  +      Y++G+TK+F++  +   A ++ L  EV 
Sbjct: 676  KSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDAL--EVR 733

Query: 958  RKILL--LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR-ALERTQAAVYLQASWRG 1014
            R+ L   +Q+ +R    R+ FL++KR+A+ IQ+ WR    RR A +R  AA  ++   RG
Sbjct: 734  RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 793

Query: 1015 Y 1015
            +
Sbjct: 794  F 794


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,760,211
Number of Sequences: 37866
Number of extensions: 4505141
Number of successful extensions: 35343
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 285
Number of HSP's successfully gapped in prelim test: 1232
Number of HSP's that attempted gapping in prelim test: 25719
Number of HSP's gapped (non-prelim): 8852
length of query: 2157
length of database: 18,247,518
effective HSP length: 118
effective length of query: 2039
effective length of database: 13,779,330
effective search space: 28096053870
effective search space used: 28096053870
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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