BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33356170 myosin IXB isoform 1 [Homo sapiens] (2157 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33356170 myosin IXB isoform 1 [Homo sapiens] 4281 0.0 gi|194272142 myosin IXB isoform 2 [Homo sapiens] 3992 0.0 gi|156119615 myosin IXA [Homo sapiens] 1211 0.0 gi|118402590 myosin XV [Homo sapiens] 449 e-125 gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 437 e-122 gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 437 e-122 gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 437 e-122 gi|122937512 myosin VIIB [Homo sapiens] 437 e-122 gi|154354979 myosin X [Homo sapiens] 433 e-120 gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 403 e-112 gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 403 e-112 gi|145275208 myosin IIIA [Homo sapiens] 399 e-110 gi|122937345 myosin VB [Homo sapiens] 395 e-109 gi|215982794 myosin VA isoform 2 [Homo sapiens] 381 e-105 gi|215982791 myosin VA isoform 1 [Homo sapiens] 381 e-105 gi|153945715 myosin VC [Homo sapiens] 379 e-104 gi|92859701 myosin VI [Homo sapiens] 367 e-101 gi|27544941 myosin IF [Homo sapiens] 367 e-101 gi|194328685 myosin IB isoform 1 [Homo sapiens] 363 e-99 gi|44889481 myosin IB isoform 2 [Homo sapiens] 363 e-99 gi|240120050 myosin IB isoform 1 [Homo sapiens] 363 e-99 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 361 4e-99 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 354 6e-97 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 354 6e-97 gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 353 8e-97 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 352 2e-96 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 352 2e-96 gi|4885503 myosin IA [Homo sapiens] 351 5e-96 gi|55956916 myosin IE [Homo sapiens] 350 7e-96 gi|124494238 myosin IC isoform a [Homo sapiens] 341 5e-93 >gi|33356170 myosin IXB isoform 1 [Homo sapiens] Length = 2157 Score = 4281 bits (11102), Expect = 0.0 Identities = 2157/2157 (100%), Positives = 2157/2157 (100%) Query: 1 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT Sbjct: 1 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60 Query: 61 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY Sbjct: 61 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120 Query: 121 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG Sbjct: 121 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180 Query: 181 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE Sbjct: 181 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240 Query: 241 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI Sbjct: 241 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300 Query: 301 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED Sbjct: 301 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360 Query: 361 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA Sbjct: 361 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420 Query: 421 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS Sbjct: 421 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480 Query: 481 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA Sbjct: 481 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540 Query: 541 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP Sbjct: 541 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600 Query: 601 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV Sbjct: 601 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660 Query: 661 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA Sbjct: 661 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720 Query: 721 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS Sbjct: 721 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780 Query: 781 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE Sbjct: 781 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840 Query: 841 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE Sbjct: 841 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900 Query: 901 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI Sbjct: 901 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960 Query: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020 Query: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG Sbjct: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080 Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK Sbjct: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140 Query: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED Sbjct: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200 Query: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV Sbjct: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260 Query: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA Sbjct: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320 Query: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE Sbjct: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380 Query: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA Sbjct: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440 Query: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES Sbjct: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500 Query: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV Sbjct: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560 Query: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK Sbjct: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620 Query: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680 Query: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA Sbjct: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740 Query: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK Sbjct: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800 Query: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN Sbjct: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860 Query: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL Sbjct: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920 Query: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI Sbjct: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980 Query: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV 2040 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV Sbjct: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEGPPAPALPCPGAPTPSPLPTV 2040 Query: 2041 AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP 2100 AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP Sbjct: 2041 AAPPRRRPSSFVTVRVKTPRRTPIMPTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPP 2100 Query: 2101 ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG 2157 ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG Sbjct: 2101 ARRPDQIHSVYITPGADLPVQGALEPLEEDGQPPGAKRRYSDPPTYCLPPASGQTNG 2157 >gi|194272142 myosin IXB isoform 2 [Homo sapiens] Length = 2022 Score = 3992 bits (10352), Expect = 0.0 Identities = 2020/2020 (100%), Positives = 2020/2020 (100%) Query: 1 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT Sbjct: 1 MSVKEAGSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGT 60 Query: 61 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY Sbjct: 61 KCYVLVEVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKY 120 Query: 121 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG Sbjct: 121 VHMQLVAQATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAG 180 Query: 181 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE Sbjct: 181 SILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGE 240 Query: 241 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI Sbjct: 241 SGSGKTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFI 300 Query: 301 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED Sbjct: 301 QVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPED 360 Query: 361 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA Sbjct: 361 YFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRA 420 Query: 421 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS Sbjct: 421 TGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDS 480 Query: 481 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA Sbjct: 481 MAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYA 540 Query: 541 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP Sbjct: 541 NEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP 600 Query: 601 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV Sbjct: 601 HATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIV 660 Query: 661 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA Sbjct: 661 ALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRAERAEKAAGMSSPGA 720 Query: 721 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS Sbjct: 721 QSHPEELPRGASTPSEKLYRDLHNQMIKSIKGLPWQGEDPRSLLQSLSRLQKPRAFILKS 780 Query: 781 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE Sbjct: 781 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840 Query: 841 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE Sbjct: 841 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900 Query: 901 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI Sbjct: 901 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960 Query: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL Sbjct: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKL 1020 Query: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG Sbjct: 1021 YRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGG 1080 Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK Sbjct: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEK 1140 Query: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED Sbjct: 1141 VPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESRED 1200 Query: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV Sbjct: 1201 ETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKTLPSGSPRPGQLERPTSLALDSRV 1260 Query: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA Sbjct: 1261 SPPAPGSAPETPEDKSKPCGSPRVQEKPDSPGGSTQIQRYLDAERLASAVELWRGKKLVA 1320 Query: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE Sbjct: 1321 AASPSAMLSQSLDLSDRHRATGAALTPTEERRTSFSTSDVSKLLPSLAKAQPAAETTDGE 1380 Query: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA Sbjct: 1381 RSAKKPAVQKKKPGDASSLPDAGLSPGSQVDSKSTFKRLFLHKTKDKKYSLEGAEELENA 1440 Query: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES Sbjct: 1441 VSGHVVLEATTMKKGLEAPSGQQHRHAAGEKRTKEPGGKGKKNRNVKIGKITVSEKWRES 1500 Query: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV Sbjct: 1501 VFRQITNANELKYLDEFLLNKINDLRSQKTPIESLFIEATEKFRSNIKTMYSVPNGKIHV 1560 Query: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK Sbjct: 1561 GYKDLMENYQIVVSNLATERGQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKK 1620 Query: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH Sbjct: 1621 RKQERAVQEHNGHVFASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSH 1680 Query: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA Sbjct: 1681 CSYTYGRKGEPGVEPGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAA 1740 Query: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK Sbjct: 1741 NRTRELRQALQTDPAAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEK 1800 Query: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN Sbjct: 1801 QEQLAAIYAVLEHLPEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDN 1860 Query: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL Sbjct: 1861 SDPLTSMKDVLKITTCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQNAPWPL 1920 Query: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI Sbjct: 1921 KLGFSSPYEGVLNKSPKTRDIQEEELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDI 1980 Query: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG 2020 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG Sbjct: 1981 TYRLPELDPRGSDEENLDSETSASTESLLEERAGRGASEG 2020 >gi|156119615 myosin IXA [Homo sapiens] Length = 2548 Score = 1211 bits (3133), Expect = 0.0 Identities = 673/1283 (52%), Positives = 835/1283 (65%), Gaps = 131/1283 (10%) Query: 7 GSSGRREQAAYHLHIYPQLSTTESQASCRVTATKDSTTSDVIKDAIASLRLDGTKCYVLV 66 G R E + L IYP + +E C + A K+ST ++VI+ I L LD TKCYVL Sbjct: 6 GGRRRFEDNEHTLRIYPG-AISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKCYVLA 64 Query: 67 EVKESGGEEWVLDANDSPVHRVLLWPRRAQDEHPQEDGYYFLLQERNADGTIKYVHMQLV 126 EVKE GGEEW+L+ D PV R++LWPR A + + Y FLL+E+N DG+I Y +Q Sbjct: 65 EVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGSLQSW 124 Query: 127 AQATATRR-LVERGLLPR-QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILV 184 + T RR ++ERG LP+ QQ DFDDLC+LP+L E LL+NL++RF +KIYTY GSIL+ Sbjct: 125 LRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVGSILI 184 Query: 185 AINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSG 244 INPFKFLPIYNPKYVKMY+N QLGKLEPH++A+ADVAY+ ML+++ NQCIVISGESGSG Sbjct: 185 VINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGESGSG 244 Query: 245 KTQSTNFLIHCLTALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSY 304 KTQSTNFLIH LTALSQKG+ASGVE+ ILGAGPVLEAFGNAKTAHNNNSSRFGKFIQV+Y Sbjct: 245 KTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVNY 304 Query: 305 LESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYL 364 E+G V GA VEKYLLEKSRLV QE +ERNYHVFYYLL G SE+ER F LKQPE+Y YL Sbjct: 305 QETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEEYHYL 364 Query: 365 NQHNLK------------------IEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLS 406 NQ K +GEDL+HDFERL+ AMEMVGFLP T++QIF++LS Sbjct: 365 NQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIFSLLS 424 Query: 407 AILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLI 466 AIL+LGN+ YKK+ T R++ +++ PEVL +S+LL+VK E+L E L RKTVTV +KLI Sbjct: 425 AILHLGNICYKKK-TYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGEKLI 483 Query: 467 LPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFED 526 LPY L+EA+T R+SMAKSLYSALFDWIV RINHALLN KD+E LSIGVLDIFGFED Sbjct: 484 LPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFGFED 543 Query: 527 FERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKP 586 +E NSFEQFCIN+ANE+LQ+YFNQHIFKLEQEEY+ EGI+WHNI Y DN CI+LISKKP Sbjct: 544 YENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLISKKP 603 Query: 587 TGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKD 646 TGL +LLDEESNFP AT+QTLL KFK QHEDN Y VMEPAFII+H+AGKVKY +KD Sbjct: 604 TGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYGVKD 663 Query: 647 FREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAVFRWAVLRAAIRAMAVLREAGRLRA 706 FREKN D+MRPDIVALLR S ++++ +IG+DPVAVFRWA+LRA RAM REAG+ Sbjct: 664 FREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGKRNI 723 Query: 707 ERAEK---------AAGMSSPGAQSHPE-----ELPRGASTPSEKLYRDLHNQMIKSIKG 752 R M S HP E+ + + R + ++G Sbjct: 724 HRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSDLQG 783 Query: 753 L--------------PWQGE---------DPRSLLQ---------SLSRLQKPRAFILKS 780 + W G SLL S L++ + ++ Sbjct: 784 MNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGILTRN 843 Query: 781 KGIKQKQIIPKNLLDSKSLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLE 840 K K K +PK+LL+ SLK + +TL DR TKSLLHLHKKKKPPSISAQFQ SL+KL+E Sbjct: 844 KNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSKLME 903 Query: 841 ALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTE 900 LG+AEP+F++CIRSNAEK L F D LVL+QLRYTGMLETVRIR+SGYS+KY+FQDF Sbjct: 904 TLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQDFVS 963 Query: 901 QFQVLLPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKI 960 F VLLP++ P + I K+ ++ NYQ+GKT VFLKE ERQ LQ+ LH+EV+R+I Sbjct: 964 HFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVLRRI 1023 Query: 961 LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSY----RVR-------------------- 996 +LLQ WFR++L R+HFL +++A+V IQ WR+Y +VR Sbjct: 1024 ILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAALLQA 1083 Query: 997 ---------RALERTQAAVYLQASWRGYWQR------------------KLYRHQKQSII 1029 R LE AA+ +Q WR Y++R K Y+ Q++ II Sbjct: 1084 SWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRKKII 1143 Query: 1030 RLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQ------- 1082 LQS CRG R+ F + + E++ E K L + QG G + Sbjct: 1144 LLQSTCRGFRARQRF-KALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFDNR 1202 Query: 1083 -VAEQGPEPAEDGGHLASEPEVQPSDRSP---LEHSSPEKEAPSPEKTLPPQKTVAAESH 1138 A + + + ++ E V SP E + + E L ++ + E Sbjct: 1203 IKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLEDL 1262 Query: 1139 EKVPSSREKRESRRQRGLEHVKF 1161 + R KRESRR R LE F Sbjct: 1263 HQKKVGRAKRESRRMRELEQAIF 1285 Score = 449 bits (1155), Expect = e-125 Identities = 240/561 (42%), Positives = 362/561 (64%), Gaps = 34/561 (6%) Query: 1471 KRTKEPGGKGKKNRNVKIGKITV-SEKWRESVFRQITNANELKYLDEFLLNKINDLRSQK 1529 K KEP K K+ R+VKI + + S W+ + I + ++LK +DEFLL K+NDL ++ Sbjct: 1823 KENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIASVSDLKSMDEFLLKKVNDLDNED 1882 Query: 1530 ----TPIESLFIEATEKFRSNIKTMYS----VPNGKIHVGYKDLMENY-QIVVSNLATER 1580 T ++ +F +A ++FR NI + YS + +GK + YKDL + QI+ + E+ Sbjct: 1883 SKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGK-SIRYKDLYALFEQILEKTMRLEQ 1941 Query: 1581 ----GQKDTNLVLNLFQSLLDEFTRGYTKNDFEPVKQSKAQKKKRKQERA--VQEHNGHV 1634 G+ + +N F+ LDE+ + +D K K ++KKR+++ V+EHNGH+ Sbjct: 1942 RDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPKTERKKRRKKETDLVEEHNGHI 2001 Query: 1635 FASYQVSIPQSCEQCLSYIWLMDKALLCSVCKMTCHKKCVHKIQSHCSYTYGRKGEPGVE 1694 F + Q SIP CE C S IW+MD+A +C +CK CHKKC K + CS Y +P + Sbjct: 2002 FKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKCCLKTTAKCSKKY----DPELS 2057 Query: 1695 PGHFGVCVDSLTSDKASVPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDP 1754 FGV + LTS+ +VP+V+EKL+ ++EMHGLYTEG+YRKSG+ N+ +ELRQ L TD Sbjct: 2058 SRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKSGSTNKIKELRQGLDTDA 2117 Query: 1755 AAVKLENFPIHAITGVLKQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHL 1814 +V L+++ IH I V KQWLR+LP PLMTF Y +FLRA+ L E++E + +Y+V++ L Sbjct: 2118 ESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGLQERKETIRGVYSVIDQL 2177 Query: 1815 PEANHNSLERLIFHLVKVALLEDVNRMSPGALAIIFAPCLLRCPDNSDPLTSMKDVLKIT 1874 + N+LERLIFHLV++AL ED NRMS ALAI+FAPC+LRCPD +DPL S++D+ K T Sbjct: 2178 SRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRCPDTTDPLQSVQDISKTT 2237 Query: 1875 TCVEMLIKEQMRKYKVKMEEISQLEAAESIAFRRLSLLRQN-APWPLKLG-FSSPYEGVL 1932 TCVE+++ EQM KYK ++++IS LE AE+ A RLSL+R++ ++ G + P V+ Sbjct: 2238 TCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMGKGRIRRGNYPGPSSPVV 2297 Query: 1933 NKSPKTRDIQEE--------ELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRL 1984 + P D+ EE E ++ +++AA E+R +L E+I+++++EKE++T+ + Sbjct: 2298 VRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEER---VLTEQIENLQKEKEELTFEM 2354 Query: 1985 PELDPRGSDEENLDSETSAST 2005 L+PR SD+E L+SE S T Sbjct: 2355 LVLEPRASDDETLESEASIGT 2375 >gi|118402590 myosin XV [Homo sapiens] Length = 3530 Score = 449 bits (1155), Expect = e-125 Identities = 235/526 (44%), Positives = 337/526 (64%), Gaps = 8/526 (1%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 +D+ L +L E +L NLK RF + IYTY GSILV++NP++ IY P+ V+ Y + L Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQYNGRAL 1284 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 G+ PH+FA+A++A+ ML + NQCI+ISGESGSGKT++T ++ L A++QK Sbjct: 1285 GENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREVMQ- 1343 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 + IL A P+LE+FGNAKT N+NSSRFGKF+++ +LE G++ GA+ +YLLEKSR+V Q Sbjct: 1344 QIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLEGGVISGAITSQYLLEKSRIVFQ 1402 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388 K+ERNYH+FY LL G+ + RQ F L++ E Y+YLNQ G+ DF RL AM Sbjct: 1403 AKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQGGNCEIAGKSDADDFRRLLAAM 1462 Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448 E++GF + IF +L++IL+LGNV ++K T +E V + +++LL++ E Sbjct: 1463 EVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELLQISPEG 1522 Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508 L + +T + T T+ +K+ P ++ A+ ARD++AK LY+ LF W++ R+N + ++D Sbjct: 1523 LQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVSPRQDT- 1581 Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568 LSI +LDI+GFED NSFEQ CINYANE LQY FN+ +F+ EQEEY E I W Sbjct: 1582 -----LSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIREQIDWQ 1636 Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVME 628 I + DN CI+LIS KP G+ +LD++ FP AT T L K H N + + Sbjct: 1637 EITFADNQPCINLISLKPYGILRILDDQCCFPQATDHTFLQKCHYHHGANPLYSKPKMPL 1696 Query: 629 PAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674 P F I+H+AGKV YQ+ F +KN D +R D++ L S + V L Sbjct: 1697 PEFTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRVVAHL 1742 Score = 122 bits (306), Expect = 4e-27 Identities = 94/340 (27%), Positives = 160/340 (47%), Gaps = 62/340 (18%) Query: 823 KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882 K +++A+FQ SL L+E + + P F+RC++ N +K+ F+ ++V+ QLRY+G+LETV Sbjct: 1766 KAHTVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQLRYSGVLETV 1825 Query: 883 RIRRSGYSAKYTFQDFTEQFQVL------LPKDAQPCREVISTLLEKMKIDKRNYQIGKT 936 RIR+ G+ + FQ F +++ L LP + C V+S L K+ Y++G + Sbjct: 1826 RIRKEGFPVRLPFQGFIDRYCCLVALKHDLPANGDMCVSVLSRL---CKVMPNMYRVGVS 1882 Query: 937 KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996 K+FLKE Q L+ R H L + AA+T+Q C R + ++ Sbjct: 1883 KLFLKEHLYQLLESM---------------------REHVLNL--AALTLQRCLRGFFIK 1919 Query: 997 RALERTQ-AAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF----------- 1044 R + + LQ+ RGY R+ Y+ ++S+++ +SL ++ R+ + Sbjct: 1920 RRFRSLRHKIILLQSRARGYLARQRYQQMRRSLVKFRSLVHAYVSRRRYLKLRAEWRCQV 1979 Query: 1045 -SQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEV 1103 ++ E+++ ++E A+ AE G QA G LA P+V Sbjct: 1980 EGALLWEQEELSKREVVAVGHLEVPAELAGLLQAVAGL--------------GLAQVPQV 2025 Query: 1104 QPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPS 1143 P R+P + P P P K V + H K P+ Sbjct: 2026 APV-RTPRLQAEPRVTLPLDINNYPMAKFV--QCHFKEPA 2062 Score = 47.0 bits (110), Expect = 2e-04 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 9/143 (6%) Query: 2007 SLLEERAGRGASEGPPAPALPCPGAP-TPSPLPTVAAPPRRRPSSFVTVRVKTPRRTPIM 2065 SL E A R A+ P P PG+P PSP + PRR + + T RR Sbjct: 819 SLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPRRSSLNLPSRLPHTWRRLSEP 878 Query: 2066 PTANIKLPPGLPSHLPRWAPGAREAAAPVRRREPPARRPDQIHSVYITPGADLPVQGALE 2125 PT +K LP H P P A AP+ RE P R P+ + + P + Sbjct: 879 PTRAVKPQVRLPFHRP---PRAGAWRAPLEHRESP-REPEDSETPWTVPPLAPSWDVDMP 934 Query: 2126 PLEEDGQP----PGAKRRYSDPP 2144 P + P G++R +S PP Sbjct: 935 PTQRPPSPWPGGAGSRRGFSRPP 957 >gi|189083802 myosin VIIA isoform 2 [Homo sapiens] Length = 2175 Score = 437 bits (1124), Expect = e-122 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 +D+ L +L E +L+NL R+ IYTY GSILVA+NP++ L IY+P++++ Y N+++ Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 G++ PH+FA+AD Y+ M R +QC +ISGESG+GKT+ST ++ L A+S G S + Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 E+ +L A P+LEAFGNAKT N+NSSRFGK+I + + + G + GA +E+YLLEKSR+ Q Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388 DERNYHVFY +L G+SE+++++ L Q DY YL N +G ++ ++ AM Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305 Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448 +++ F +I +L+AIL+LGN+ Y+ R + EV L T + LL+V Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365 Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508 L+ LT R +T + + P S +A+ RD+ K +Y LF WIV +IN A+ + Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425 Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568 S SIG+LDIFGFE+F NSFEQ CIN+ANE LQ +F +H+FKLEQEEY E I W Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485 Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627 +I +TDN + +I+ KP + L+DEES FP T T+L K QH+ N Y Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545 Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678 E F I HFAG V Y+ + F EKN D + DI+ L+ S + +++++ D Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596 Score = 162 bits (409), Expect = 4e-39 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%) Query: 821 KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880 +K+ P++S+QF+ SL L+ LG +PFF+RCI+ N KK + FD L ++QLRY+GM+E Sbjct: 604 RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663 Query: 881 TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935 T+RIRR+GY +Y+F +F E+++VLLP K A R + E + ++QIGK Sbjct: 664 TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723 Query: 936 TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995 TK+FLK+ L+ + + +++LLQ R +R +FL++K AA IQ WR + Sbjct: 724 TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783 Query: 996 RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031 R+ AL R+ Q + QA R Y RK +RH+ +++ + Sbjct: 784 RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843 Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091 Q+ RG + R+ + ++ +AE R E R EE + E + A Sbjct: 844 QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889 Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144 ++ + + R E EKEA +K L Q A HE V S Sbjct: 890 KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940 >gi|189083800 myosin VIIA isoform 3 [Homo sapiens] Length = 1204 Score = 437 bits (1124), Expect = e-122 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 +D+ L +L E +L+NL R+ IYTY GSILVA+NP++ L IY+P++++ Y N+++ Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 G++ PH+FA+AD Y+ M R +QC +ISGESG+GKT+ST ++ L A+S G S + Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 E+ +L A P+LEAFGNAKT N+NSSRFGK+I + + + G + GA +E+YLLEKSR+ Q Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388 DERNYHVFY +L G+SE+++++ L Q DY YL N +G ++ ++ AM Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305 Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448 +++ F +I +L+AIL+LGN+ Y+ R + EV L T + LL+V Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365 Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508 L+ LT R +T + + P S +A+ RD+ K +Y LF WIV +IN A+ + Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425 Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568 S SIG+LDIFGFE+F NSFEQ CIN+ANE LQ +F +H+FKLEQEEY E I W Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485 Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627 +I +TDN + +I+ KP + L+DEES FP T T+L K QH+ N Y Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545 Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678 E F I HFAG V Y+ + F EKN D + DI+ L+ S + +++++ D Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596 Score = 162 bits (409), Expect = 4e-39 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%) Query: 821 KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880 +K+ P++S+QF+ SL L+ LG +PFF+RCI+ N KK + FD L ++QLRY+GM+E Sbjct: 604 RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663 Query: 881 TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935 T+RIRR+GY +Y+F +F E+++VLLP K A R + E + ++QIGK Sbjct: 664 TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723 Query: 936 TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995 TK+FLK+ L+ + + +++LLQ R +R +FL++K AA IQ WR + Sbjct: 724 TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783 Query: 996 RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031 R+ AL R+ Q + QA R Y RK +RH+ +++ + Sbjct: 784 RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843 Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091 Q+ RG + R+ + ++ +AE R E R EE + E + A Sbjct: 844 QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889 Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144 ++ + + R E EKEA +K L Q A HE V S Sbjct: 890 KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940 >gi|189083798 myosin VIIA isoform 1 [Homo sapiens] Length = 2215 Score = 437 bits (1124), Expect = e-122 Identities = 228/531 (42%), Positives = 331/531 (62%), Gaps = 3/531 (0%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 +D+ L +L E +L+NL R+ IYTY GSILVA+NP++ L IY+P++++ Y N+++ Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKI 127 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 G++ PH+FA+AD Y+ M R +QC +ISGESG+GKT+ST ++ L A+S G S + Sbjct: 128 GEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAIS--GQHSWI 185 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 E+ +L A P+LEAFGNAKT N+NSSRFGK+I + + + G + GA +E+YLLEKSR+ Q Sbjct: 186 EQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQ 245 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQAM 388 DERNYHVFY +L G+SE+++++ L Q DY YL N +G ++ ++ AM Sbjct: 246 ALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVDSQEYANIRSAM 305 Query: 389 EMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREI 448 +++ F +I +L+AIL+LGN+ Y+ R + EV L T + LL+V Sbjct: 306 KVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLLEVNPPD 365 Query: 449 LVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVE 508 L+ LT R +T + + P S +A+ RD+ K +Y LF WIV +IN A+ + Sbjct: 366 LMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIYKPPSQD 425 Query: 509 EAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWH 568 S SIG+LDIFGFE+F NSFEQ CIN+ANE LQ +F +H+FKLEQEEY E I W Sbjct: 426 VKNSRRSIGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEYDLESIDWL 485 Query: 569 NIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN-KYFLGTPVM 627 +I +TDN + +I+ KP + L+DEES FP T T+L K QH+ N Y Sbjct: 486 HIEFTDNQDALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNSQHKLNANYIPPKNNH 545 Query: 628 EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678 E F I HFAG V Y+ + F EKN D + DI+ L+ S + +++++ D Sbjct: 546 ETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSRNKFIKQIFQAD 596 Score = 162 bits (409), Expect = 4e-39 Identities = 112/353 (31%), Positives = 175/353 (49%), Gaps = 45/353 (12%) Query: 821 KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880 +K+ P++S+QF+ SL L+ LG +PFF+RCI+ N KK + FD L ++QLRY+GM+E Sbjct: 604 RKRSPTLSSQFKRSLELLMRTLGACQPFFVRCIKPNEFKKPMLFDRHLCVRQLRYSGMME 663 Query: 881 TVRIRRSGYSAKYTFQDFTEQFQVLLP--KDAQ---PCREVISTLLEKMKIDKRNYQIGK 935 T+RIRR+GY +Y+F +F E+++VLLP K A R + E + ++QIGK Sbjct: 664 TIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAVLGTHDDWQIGK 723 Query: 936 TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995 TK+FLK+ L+ + + +++LLQ R +R +FL++K AA IQ WR + Sbjct: 724 TKIFLKDHHDMLLEVERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRHWRGHNC 783 Query: 996 RR-------------ALERT-----------QAAVYLQASWRGYWQRKLYRHQKQSIIRL 1031 R+ AL R+ Q + QA R Y RK +RH+ +++ + Sbjct: 784 RKNYGLMRLGFLRLQALHRSRKLHQQYRLARQRIIQFQARCRAYLVRKAFRHRLWAVLTV 843 Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPA 1091 Q+ RG + R+ + ++ +AE R E R EE + E + A Sbjct: 844 QAYARGMIARR-----LHQRLRAEYLWRLEAEKMRLAEEE---------KLRKEMSAKKA 889 Query: 1092 EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSS 1144 ++ + + R E EKEA +K L Q A HE V S Sbjct: 890 KEEAERKHQERLAQLAREDAERELKEKEAARRKKELLEQMERA--RHEPVNHS 940 >gi|122937512 myosin VIIB [Homo sapiens] Length = 2116 Score = 437 bits (1123), Expect = e-122 Identities = 224/538 (41%), Positives = 335/538 (62%), Gaps = 3/538 (0%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P DD+ L +L E ++ NL R+ Q KIYTY GSILVA+NPF+ LP+Y + V+ Sbjct: 61 PNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYTLEQVQ 120 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQ 261 +Y ++ +G+L PHVFA+A+ Y++M R + +QC +ISGESG+GKT++T ++ L +S Sbjct: 121 LYYSRHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLILQFLATIS- 179 Query: 262 KGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLE 321 G S +E+ +L A P+LEAFGNAKT N+NSSRFGK+I + + SG++ GA +E++LLE Sbjct: 180 -GQHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYFNPSGVIEGARIEQFLLE 238 Query: 322 KSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDF 381 KSR+ Q +ERNYH+FY +L+GVS E++Q L P +Y YL N +G + D+ Sbjct: 239 KSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTMGNCTSCEGLNDAKDY 298 Query: 382 ERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQL 441 ++ AM+++ F + + +L+AIL+LGNV + + +V T+ +L Sbjct: 299 AHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVMETPAFPTVMKL 358 Query: 442 LKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHAL 501 L+V+ + L + L K + + + ++++A RD+ K +Y LF WIV +IN A+ Sbjct: 359 LEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLFLWIVKKINAAI 418 Query: 502 LNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQ 561 + +IG+LDIFGFE+FE NSFEQ CIN+ANE LQ +F QH+F +EQEEY+ Sbjct: 419 FTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQHVFTMEQEEYR 478 Query: 562 GEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYF 621 E I+W I YTDN + L++ KP + LLDEES FP T T+L K H +NK F Sbjct: 479 SENISWDYIHYTDNRPTLDLLALKPMSIISLLDEESRFPQGTDLTMLQKLNSVHANNKAF 538 Query: 622 LGTP-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMD 678 L + + F I HFAG+V YQ + F EKN D + DI+ L+ S + ++RE+ ++ Sbjct: 539 LQPKNIHDARFGIAHFAGEVYYQAEGFLEKNRDVLSTDILTLVYSSKNKFLREIFNLE 596 Score = 158 bits (399), Expect = 6e-38 Identities = 94/255 (36%), Positives = 150/255 (58%), Gaps = 14/255 (5%) Query: 810 RTTKSLLHLHKK----KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFD 865 R K+ HL K K+P ++ +QF+ SL++L++ L +P+FIRCI+ N KK L FD Sbjct: 608 RQAKAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYKKPLLFD 667 Query: 866 DELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQ-----PCREVISTL 920 EL L+QLRY+GM+ETV IR+SG+ +YTF++F+++F VLLP + R++ + Sbjct: 668 RELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMRMQLQGKLRQMTLGI 727 Query: 921 LEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK 980 + ++++ GKTK+FL++ + L+ + + R L +Q R R+ FL+ + Sbjct: 728 TDVWLRTDKDWKAGKTKIFLRDHQDTLLEVQRSQVLDRAALSIQKVLRGYRYRKEFLRQR 787 Query: 981 RAAVTIQACWRSYRVRRALERTQAAV-YLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039 RAAVT+QA WR Y RR + LQA R + Y+ +Q ++LQ+LCRG+L Sbjct: 788 RAAVTLQAWWRGYCNRRNFKLILVGFERLQAIARSQPLARQYQAMRQRTVQLQALCRGYL 847 Query: 1040 QRKSFSQMISEKQKA 1054 R Q + K++A Sbjct: 848 VR----QQVQAKRRA 858 >gi|154354979 myosin X [Homo sapiens] Length = 2058 Score = 433 bits (1113), Expect = e-120 Identities = 228/555 (41%), Positives = 346/555 (62%), Gaps = 21/555 (3%) Query: 128 QATATRRLVERGLLPRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAIN 187 Q+T T + V + P + DD+ +L EL G+++ NL R+ + +IYTY GSIL ++N Sbjct: 46 QSTITHQKVT-AMHPTNEEGVDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVN 104 Query: 188 PFKFLP-IYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKT 246 P++ + +Y P ++ Y + LG+L PH+FA+A+ Y + ++ NQCI+ISGESG+GKT Sbjct: 105 PYQPIAGLYEPATMEQYSRRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKT 164 Query: 247 QSTNFLIHCLTALSQ-------KGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKF 299 +ST ++ L+ +SQ K S VER IL + P++EAFGNAKT +NNNSSRFGKF Sbjct: 165 ESTKLILKFLSVISQQSLELSLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKF 224 Query: 300 IQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPE 359 +Q++ + G ++G + YLLEK+R+V Q ERNYH+FY LL G+ EER+EF L PE Sbjct: 225 VQLNICQKGNIQGGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPE 284 Query: 360 DYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR 419 +Y YLNQ + + F + AM+++ F +++ +L+ IL+LGN+ + Sbjct: 285 NYHYLNQSGCVEDKTISDQESFREVITAMDVMQFSKEEVREVSRLLAGILHLGNIEFITA 344 Query: 420 ATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARD 479 G +V L ++LL + L + LT+R ++++ P ++ +A+ +RD Sbjct: 345 G-----GAQVSFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRD 399 Query: 480 SMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINY 539 S+A +LY+ F+W++ +IN + +D + SIG+LDIFGFE+FE N FEQF INY Sbjct: 400 SLAMALYACCFEWVIKKINSRIKGNEDFK------SIGILDIFGFENFEVNHFEQFNINY 453 Query: 540 ANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNF 599 ANE+LQ YFN+HIF LEQ EY EG+ W +I + DN C+ LI KK GL L++EES+F Sbjct: 454 ANEKLQEYFNKHIFSLEQLEYSREGLVWEDIDWIDNGECLDLIEKK-LGLLALINEESHF 512 Query: 600 PHATSQTLLAKFKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDI 659 P AT TLL K QH +N +++ V F ++H+AG+V+Y ++ EKN D R D+ Sbjct: 513 PQATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDTFRDDL 572 Query: 660 VALLRGSDSSYVREL 674 + LLR S ++ +L Sbjct: 573 LNLLRESRFDFIYDL 587 Score = 164 bits (415), Expect = 9e-40 Identities = 116/366 (31%), Positives = 183/366 (50%), Gaps = 15/366 (4%) Query: 792 NLLDSKSLKLIISMTLH--DRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFF 849 NLL I + H R + L K + P++S+QF+ SL+ L+ L + PFF Sbjct: 574 NLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPFF 633 Query: 850 IRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKD 909 +RCI+ N +K FD +VL QLRY+GMLETVRIR++GY+ + FQDF ++++VL+ Sbjct: 634 VRCIKPNMQKMPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL 693 Query: 910 AQP--CREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWF 967 A P R ++LL+ +Q+GKTKVFL+E+ Q L++ EV +++++ Sbjct: 694 ALPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHV 753 Query: 968 RMVLERRHFLQMKRAAVTIQACWRSYRVRRA-LERTQAAVYLQASWRGYWQRKLYRHQKQ 1026 L R+ + ++ V IQ +R++ +RR L +AA+ Q RG R++YR Sbjct: 754 LGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIARRVYR---- 809 Query: 1027 SIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVAEQ 1086 Q L Q + Q EK+K EE+ERE E R AE Q + +Q + Sbjct: 810 -----QLLAEKREQEEKKKQEEEEKKKREEEERER-ERERREAELRAQQEEETRKQQELE 863 Query: 1087 GPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSRE 1146 + ++ L E E Q ++ E EKE ++ Q+ E+ + R Sbjct: 864 ALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERR 923 Query: 1147 KRESRR 1152 +E RR Sbjct: 924 DQELRR 929 >gi|134288915 myosin IIIB isoform 1 [Homo sapiens] Length = 1314 Score = 403 bits (1036), Expect = e-112 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 DDL NL L E ++ L+ R+ IYTY G IL+A+NPF+ L IY+P++ ++Y + Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 PH+FA AD AY M+ +QCIVISGESGSGKT+S + ++ LT L K + Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 IL ++EAFGN+ TA N+NSSRFGK++++ + +G+V GA + +YLLEKSR++ Q Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524 Query: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383 E+N+H+FYY+ G+ +++ +F+L + + Y+ + I E + FE Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584 Query: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442 ++ ++GF ++ +L+ IL +GN+ + ++ + + EV E L + +L Sbjct: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644 Query: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502 + E L E LT VT + +I ++ A RD+M+K+LY LF WIV RIN L Sbjct: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704 Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562 +++ A +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ Sbjct: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764 Query: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619 EGI + Y DN + + +KP GL LLDEES FP AT QTL+ KF EDN K Sbjct: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820 Query: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679 YF +E F IQH+AGKV Y EKN D + D+V +LR S++ +++L + Sbjct: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880 Query: 680 VAVFRWAVLRAAI 692 A RA I Sbjct: 881 TKTGNLAQTRARI 893 Score = 96.3 bits (238), Expect = 3e-19 Identities = 61/173 (35%), Positives = 103/173 (59%), Gaps = 10/173 (5%) Query: 823 KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882 K ++++ F+ SL LL + +P F+RCI+ N +++ L F E VL QLR TG+LETV Sbjct: 927 KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986 Query: 883 RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939 IRR GYS + F++F +++ L Q +E +LEK ++D ++ +GKTKVF Sbjct: 987 SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044 Query: 940 LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQA 988 LK + L L REV+ ++++LQ++ + L R + +++ + A+ IQ+ Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQS 1096 >gi|134288892 myosin IIIB isoform 2 [Homo sapiens] Length = 1341 Score = 403 bits (1036), Expect = e-112 Identities = 224/553 (40%), Positives = 327/553 (59%), Gaps = 14/553 (2%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 DDL NL L E ++ L+ R+ IYTY G IL+A+NPF+ L IY+P++ ++Y + Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKR 405 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGV 268 PH+FA AD AY M+ +QCIVISGESGSGKT+S + ++ LT L K + Sbjct: 406 ASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLG-KANNQTL 464 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 IL ++EAFGN+ TA N+NSSRFGK++++ + +G+V GA + +YLLEKSR++ Q Sbjct: 465 REKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQ 524 Query: 329 EKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDFER 383 E+N+H+FYY+ G+ +++ +F+L + + Y+ + I E + FE Sbjct: 525 AAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEA 584 Query: 384 LKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQLL 442 ++ ++GF ++ +L+ IL +GN+ + ++ + + EV E L + +L Sbjct: 585 IQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVL 644 Query: 443 KVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502 + E L E LT VT + +I ++ A RD+M+K+LY LF WIV RIN L Sbjct: 645 CISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQ 704 Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562 +++ A +++G+LDIFGFE+F+RNSFEQ CIN ANEQ+QYYFNQH+F LEQ EYQ Sbjct: 705 PDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQN 764 Query: 563 EGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDN---K 619 EGI + Y DN + + +KP GL LLDEES FP AT QTL+ KF EDN K Sbjct: 765 EGIDAVPVEYEDNRPLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKF----EDNLRCK 820 Query: 620 YFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDP 679 YF +E F IQH+AGKV Y EKN D + D+V +LR S++ +++L + Sbjct: 821 YFWRPKGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTSENMLLQQLFSIPL 880 Query: 680 VAVFRWAVLRAAI 692 A RA I Sbjct: 881 TKTGNLAQTRARI 893 Score = 110 bits (274), Expect = 2e-23 Identities = 95/351 (27%), Positives = 161/351 (45%), Gaps = 43/351 (12%) Query: 823 KPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETV 882 K ++++ F+ SL LL + +P F+RCI+ N +++ L F E VL QLR TG+LETV Sbjct: 927 KRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRERVLAQLRSTGILETV 986 Query: 883 RIRRSGYSAKYTFQDFTEQFQVLLPKDAQ---PCREVISTLLEKMKIDKRNYQIGKTKVF 939 IRR GYS + F++F +++ L Q +E +LEK ++D ++ +GKTKVF Sbjct: 987 SIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLASKESCVAILEKSRLD--HWVLGKTKVF 1044 Query: 940 LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMK----RAAVTIQACWRSYRV 995 LK + L L REV+ ++++LQ++ + L R + +++ + A+ IQ+ WR Y Sbjct: 1045 LKYYHVEQL-NLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKGAIAIQSAWRGYDA 1103 Query: 996 RRALE-----RTQAAVYLQA-----------SWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039 RR + R ++A + QA S R Q S + RG + Sbjct: 1104 RRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAGTRGSAEVQDCSEPGDHKVLRGSV 1163 Query: 1040 QRKSFSQMISEKQKAEEKEREALEAARAG--------------AEEGGQGQAAGGQQVAE 1085 R+S SQ S + + + G A + +G ++ Sbjct: 1164 HRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSPKGCDIFAGHANKHSVSGTDLLSS 1223 Query: 1086 Q--GPEPAEDGGHLASEPEVQPSDRS-PLEHSSPEKEAPSPEKTLPPQKTV 1133 + P P + G L P+ S+ +H +P + P+ P+ T+ Sbjct: 1224 RICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRRCQQPKMLSSPEDTM 1274 >gi|145275208 myosin IIIA [Homo sapiens] Length = 1616 Score = 399 bits (1026), Expect = e-110 Identities = 218/535 (40%), Positives = 327/535 (61%), Gaps = 8/535 (1%) Query: 147 DFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQ 206 D DDL L L E + + L+ + + +IY Y G IL+A+NPF+ L +Y+ K+ K+Y Sbjct: 339 DVDDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGS 398 Query: 207 QLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYAS 266 + PH+FA+AD+ Y +M+ +QCIVISGESG+GKT++ + L+ LT L + + Sbjct: 399 KRTASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNRT 458 Query: 267 GVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLV 326 ++ IL ++EAFGNA T N+NSSRFGK++++ + SG V GA + +YLLEKSR++ Sbjct: 459 -LQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVI 517 Query: 327 SQEKDERNYHVFYYLLLGVSEEER-QEFQLKQPEDYFYLNQHNLK----IEDGEDLKHDF 381 Q E+N+H+FYY+ G++E+++ ++L + + YL +L+ I + K + Sbjct: 518 HQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENKPPRYLQNDHLRTVQDIMNNSFYKSQY 577 Query: 382 ERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGRE-EGLEVGPPEVLDTLSQ 440 E ++Q +++GF I+++L+AIL +GN+ + AT + + + L+ + Sbjct: 578 ELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTALENCAS 637 Query: 441 LLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHA 500 LL ++ + L E LT VT + +I P ++ +A RD+MAK+LY LF WIV IN Sbjct: 638 LLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIVNCINSL 697 Query: 501 LLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEY 560 L + LSIG+LDIFGFE+F++NSFEQ CIN ANEQ+QYY+NQH+F EQ EY Sbjct: 698 LKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFAWEQNEY 757 Query: 561 QGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKY 620 E + I Y DN + + +KP GL LLDEES FP AT QTL+ KF + + ++Y Sbjct: 758 LNEDVDARVIEYEDNWPLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKF-EGNLKSQY 816 Query: 621 FLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELI 675 F ME +F I H+AGKV Y F KN D + DIV LLR SD+S +R+L+ Sbjct: 817 FWRPKRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVLLLRSSDNSVIRQLV 871 Score = 120 bits (302), Expect = 1e-26 Identities = 114/456 (25%), Positives = 212/456 (46%), Gaps = 48/456 (10%) Query: 806 TLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFD 865 T H R T ++ K ++++ F+ SL LL + +P F+RCI+ N+E++ +D Sbjct: 912 TRHARETTNM-------KTQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARKYD 964 Query: 866 DELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPCR---EVISTLLE 922 E VL QLRYTG+LET RIRR G+S + F +F +++ +L K ++ R + +T+LE Sbjct: 965 KEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLCYKSSEEPRMSPDTCATILE 1024 Query: 923 KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQM--- 979 K +D N+ +GKTKVFLK + L + +E + K++L+Q+ R L R + ++ Sbjct: 1025 KAGLD--NWALGKTKVFLKYYHVEQL-NLMRKEAIDKLILIQACVRAFLCSRRYQKIQEK 1081 Query: 980 -KRAAVTIQACWRSYRVRRALE-----RTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQS 1033 K +A+ IQ+ R + VR+ + + A +Q S + + +K + + ++S ++ Q+ Sbjct: 1082 RKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQA 1141 Query: 1034 ---------LCRGHLQRKSFSQMISEKQKAEEKEREALEAARAGAEEGGQGQAAGGQQVA 1084 + S S + + K EE+ A+E+ + + ++V Sbjct: 1142 ENAISANERFISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYEEEVK 1201 Query: 1085 EQ----GPEPA---------EDGGHLASEPEVQPSDRSPLEHSSPEKEAPSPEKTLPPQK 1131 ++ GPE + E+ +L + + +S + + E+ + +K Sbjct: 1202 QEFYLVGPEVSPKQKSVKDLEENSNLRKVEKEEAMIQSYYQRYTEERNCEESKAAYLERK 1261 Query: 1132 TVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSLL 1191 ++ VP E E+ ++ LE Q Q+ ++ S VTQ + Sbjct: 1262 AISERPSYPVPWLAE-NETSFKKTLEPTLSQRSIYQNANSMEKEKKTS-VVTQRAPICSQ 1319 Query: 1192 EDKKESREDETLLVVETEAENTSQKQPTEQPQAMAV 1227 E+ + ET V E + E +Q Q E A+ + Sbjct: 1320 EEGRGRLRHET--VKERQVEPVTQAQEEEDKAAVFI 1353 >gi|122937345 myosin VB [Homo sapiens] Length = 1848 Score = 395 bits (1016), Expect = e-109 Identities = 225/536 (41%), Positives = 308/536 (57%), Gaps = 12/536 (2%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207 +DL L L E +L NLK RFL+ IYTY G +LVAINP++ LPIY + Y Q Sbjct: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTYSGQN 131 Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267 +G ++PH+FA+A+ AY M R NQ I++SGESG+GKT S + + + + Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSASETN 191 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 +E +L + P++EA GNAKT N+NSSRFGK+IQ+ + + + GA + YLLEKSR+V Sbjct: 192 IEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTYLLEKSRVVF 251 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 Q DERNYH+FY L E +E L ED+FY +Q +G D DFE+ +QA Sbjct: 252 QADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFYTSQGGDTSIEGVDDAEDFEKTRQA 311 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV-LDTLSQLLKVKR 446 ++G + + IF ++++IL+LG+V + G + + P +V L +LL V+ Sbjct: 312 FTLLGVKESHQMSIFKIIASILHLGSVAIQAERDG--DSCSISPQDVYLSNFCRLLGVEH 369 Query: 447 EILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKD 506 + L RK VT ++ + SL + I AR+++AK +Y+ LF WIV IN AL Sbjct: 370 SQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKALHTSLK 429 Query: 507 VEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGIT 566 IGVLDI+GFE FE NSFEQFCINYANE+LQ FN H+FKLEQEEY E I Sbjct: 430 QHS-----FIGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMKEQIP 484 Query: 567 WHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPV 626 W I + DN CI LI K G+ LLDEE P T Q K +H +++F + Sbjct: 485 WTLIDFYDNQPCIDLIEAK-LGILDLLDEECKVPKGTDQNWAQKLYDRHSSSQHFQKPRM 543 Query: 627 MEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELI--GMDPV 680 AFII HFA KV+Y F EKN D + + + +L+ S V +L DPV Sbjct: 544 SNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQINILKASKFPLVADLFHDDKDPV 599 Score = 122 bits (307), Expect = 3e-27 Identities = 72/251 (28%), Positives = 135/251 (53%), Gaps = 14/251 (5%) Query: 810 RTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELV 869 R+ + + + K+ ++ QF+TSL+ L+E L P ++RCI+ N EK FD + Sbjct: 615 RSARPPMKVSNKEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFHFDPKRA 674 Query: 870 LQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPK-------DAQPCREVISTLLE 922 +QQLR G+LET+RI +GY +++ + DF +++VL+ K CR V+ L++ Sbjct: 675 VQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKKRELANTDKKAICRSVLENLIK 734 Query: 923 KMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRA 982 D +Q G+TK+F + + L++ + +++Q R L++ + ++K A Sbjct: 735 ----DPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGA 790 Query: 983 AVTIQACWRSYRVRRA---LERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHL 1039 +T+Q R + RR L R +AAV LQ +R R+ Y+ +++ + +Q+ R Sbjct: 791 TLTLQRYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVRRAAVVIQAFTRAMF 850 Query: 1040 QRKSFSQMISE 1050 R+++ Q++ E Sbjct: 851 VRRTYRQVLME 861 Score = 43.1 bits (100), Expect = 0.003 Identities = 68/287 (23%), Positives = 122/287 (42%), Gaps = 34/287 (11%) Query: 938 VFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR 997 +F++ T RQ L E K +Q R + RRHF +++ AA+ IQ +R + RR Sbjct: 849 MFVRRTYRQVLME-------HKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARR 901 Query: 998 ALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQ-SLCRGHLQRKSFSQMISEKQKAEE 1056 L+ A+ ++A + +R L + +++LQ + + + K+ S+ +S Sbjct: 902 ELK----ALRIEARSAEHLKR-LNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYT 956 Query: 1057 KEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSP 1116 E E L+ +E Q + G+ + + E E L +E + S+R LE Sbjct: 957 MEVERLK------KELVHYQQSPGEDTSLRLQEEVES---LRTELQRAHSERKILE---- 1003 Query: 1117 EKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVK--FQNKHIQSCKEESA 1174 +A S EK +K VA E EK + Q + QN ++ ++ Sbjct: 1004 --DAHSREKD-ELRKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKEL 1060 Query: 1175 LREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQ 1221 E SR + S LE + ++ DE ++ +T ++ P+ Q Sbjct: 1061 EEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGH---RRNPSNQ 1104 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 381 bits (978), Expect = e-105 Identities = 224/539 (41%), Positives = 307/539 (56%), Gaps = 16/539 (2%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207 +DL L L E +L NL+ RF+ K IYTY G +LVAINP++ LPIY + Y Q Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131 Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267 +G ++PH+FA+A+ AY M R NQ I++SGESG+GKT S + + +S + Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 VE +L + P++E+ GNAKT N+NSSRFGK+I++ + + + GA + YLLEKSR+V Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 Q ++ERNYH+FY L E + +L +++ Y Q + +G D + +QA Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPP--EVLDTLSQLLKVK 445 ++G + + IF +L+ IL+LGNV + T R+ PP E L L+ V Sbjct: 312 CTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLCIFCDLMGVD 367 Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505 E + L RK T + I P S +A ARD++AK +Y+ LF+WIV +N AL Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL---- 423 Query: 506 DVEEAVSCLS-IGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEG 564 AV S IGVLDI+GFE FE NSFEQFCINYANE+LQ FN H+FKLEQEEY E Sbjct: 424 --HSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481 Query: 565 ITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGT 624 I W I + DN CI+LI K G+ LLDEE P T T K H + Sbjct: 482 IPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540 Query: 625 P-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAV 682 P + AFIIQHFA KV+YQ + F EKN D + + + +L+ S + EL D A+ Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599 Score = 149 bits (375), Expect = 4e-35 Identities = 118/433 (27%), Positives = 205/433 (47%), Gaps = 25/433 (5%) Query: 821 KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880 K+ ++ QF+ SL+ L+E L P ++RCI+ N K FD++ +QQLR G+LE Sbjct: 629 KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688 Query: 881 TVRIRRSGYSAKYTFQDFTEQFQVLL-PKDAQPCR-EVISTLLEKMKIDKRNYQIGKTKV 938 T+RI +G+ +++T+Q+F +++VL+ KD R + +LEK+ +DK YQ GKTK+ Sbjct: 689 TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748 Query: 939 FLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR-- 996 F + + L++ ++ + +Q R L R+ +L+M++AA+T+Q R Y+ R Sbjct: 749 FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808 Query: 997 -RALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE 1055 + L RT+AA +Q WR Y R+ Y+ ++ + I LQS RG L R + +++ E + Sbjct: 809 AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVI 868 Query: 1056 EKEREALEAARAGAEEGGQG----QAAGGQQVAEQGPEPAEDGG---------HLASEPE 1102 ++R AR + Q + +A++ + + H+ E + Sbjct: 869 IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928 Query: 1103 VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQ 1162 + R E + K+ + L + + EK+ S E R Q E K Sbjct: 929 IMQLQRKVDEQN---KDYKCLVEKLTNLEGIYNSETEKLRSDLE----RLQLSEEEAKVA 981 Query: 1163 NKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQP 1222 + S +EE A T+ + + E +++ LV + ENT KQ E Sbjct: 982 TGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041 Query: 1223 QAMAVGKVSEETE 1235 V + E TE Sbjct: 1042 NHRIVQQAKEMTE 1054 Score = 48.1 bits (113), Expect = 9e-05 Identities = 78/367 (21%), Positives = 154/367 (41%), Gaps = 50/367 (13%) Query: 914 REVISTLLEK---MKIDKRNYQIGKTK-VFLKETERQALQETLHREVVR--KILLLQSWF 967 R +T+++K M + +R Y+I + + L+ R L +R+++R K +++Q Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873 Query: 968 RMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQS 1027 R L R H+ + A + +Q C+R +R L++ + + +KL+ + Sbjct: 874 RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-----KKLHIGMENK 928 Query: 1028 IIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAARAGAEEGGQGQAAGG 1080 I++LQ + Q K + ++ + E EK R LE + EE + A G Sbjct: 929 IMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE---AKVATG 983 Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPL-EHSSPEKEAP-------SPEKTLPPQKT 1132 + ++ Q E+ L + E S++ + EH+ K+ E TL Q+ Sbjct: 984 RVLSLQ-----EEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEK 1038 Query: 1133 VAAESHEKVPSSREKRESRRQRGLEHVKFQNKHI--QSCKEESALREPSRRVTQEQGVSL 1190 A +H V ++E E+ ++ +E K + + + ++ L E SR Sbjct: 1039 EAL-NHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSR---------- 1087 Query: 1191 LEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETE-KTLPSGSPRPGQLE 1249 LE++ + ++E L+V + T SE E + +PS + P + + Sbjct: 1088 LEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK 1147 Query: 1250 RPTSLAL 1256 P ++L Sbjct: 1148 VPLDMSL 1154 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 381 bits (978), Expect = e-105 Identities = 224/539 (41%), Positives = 307/539 (56%), Gaps = 16/539 (2%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207 +DL L L E +L NL+ RF+ K IYTY G +LVAINP++ LPIY + Y Q Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAYSGQN 131 Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267 +G ++PH+FA+A+ AY M R NQ I++SGESG+GKT S + + +S + Sbjct: 132 MGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSASEAN 191 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 VE +L + P++E+ GNAKT N+NSSRFGK+I++ + + + GA + YLLEKSR+V Sbjct: 192 VEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGANMRTYLLEKSRVVF 251 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 Q ++ERNYH+FY L E + +L +++ Y Q + +G D + +QA Sbjct: 252 QAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNYTKQGGSPVIEGVDDAKEMAHTRQA 311 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPP--EVLDTLSQLLKVK 445 ++G + + IF +L+ IL+LGNV + T R+ PP E L L+ V Sbjct: 312 CTLLGISESHQMGIFRILAGILHLGNVGF----TSRDADSCTIPPKHEPLCIFCDLMGVD 367 Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505 E + L RK T + I P S +A ARD++AK +Y+ LF+WIV +N AL Sbjct: 368 YEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQAL---- 423 Query: 506 DVEEAVSCLS-IGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEG 564 AV S IGVLDI+GFE FE NSFEQFCINYANE+LQ FN H+FKLEQEEY E Sbjct: 424 --HSAVKQHSFIGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEQ 481 Query: 565 ITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGT 624 I W I + DN CI+LI K G+ LLDEE P T T K H + Sbjct: 482 IPWTLIDFYDNQPCINLIESK-LGILDLLDEECKMPKGTDDTWAQKLYNTHLNKCALFEK 540 Query: 625 P-VMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRELIGMDPVAV 682 P + AFIIQHFA KV+YQ + F EKN D + + + +L+ S + EL D A+ Sbjct: 541 PRLSNKAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKVLKSSKFKMLPELFQDDEKAI 599 Score = 149 bits (375), Expect = 4e-35 Identities = 118/433 (27%), Positives = 205/433 (47%), Gaps = 25/433 (5%) Query: 821 KKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLE 880 K+ ++ QF+ SL+ L+E L P ++RCI+ N K FD++ +QQLR G+LE Sbjct: 629 KEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTFDEKRAVQQLRACGVLE 688 Query: 881 TVRIRRSGYSAKYTFQDFTEQFQVLL-PKDAQPCR-EVISTLLEKMKIDKRNYQIGKTKV 938 T+RI +G+ +++T+Q+F +++VL+ KD R + +LEK+ +DK YQ GKTK+ Sbjct: 689 TIRISAAGFPSRWTYQEFFSRYRVLMKQKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKI 748 Query: 939 FLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR-- 996 F + + L++ ++ + +Q R L R+ +L+M++AA+T+Q R Y+ R Sbjct: 749 FFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCY 808 Query: 997 -RALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE 1055 + L RT+AA +Q WR Y R+ Y+ ++ + I LQS RG L R + +++ E + Sbjct: 809 AKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVI 868 Query: 1056 EKEREALEAARAGAEEGGQG----QAAGGQQVAEQGPEPAEDGG---------HLASEPE 1102 ++R AR + Q + +A++ + + H+ E + Sbjct: 869 IQKRVRGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENK 928 Query: 1103 VQPSDRSPLEHSSPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQ 1162 + R E + K+ + L + + EK+ S E R Q E K Sbjct: 929 IMQLQRKVDEQN---KDYKCLVEKLTNLEGIYNSETEKLRSDLE----RLQLSEEEAKVA 981 Query: 1163 NKHIQSCKEESALREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQP 1222 + S +EE A T+ + + E +++ LV + ENT KQ E Sbjct: 982 TGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEAL 1041 Query: 1223 QAMAVGKVSEETE 1235 V + E TE Sbjct: 1042 NHRIVQQAKEMTE 1054 Score = 48.1 bits (113), Expect = 9e-05 Identities = 78/367 (21%), Positives = 154/367 (41%), Gaps = 50/367 (13%) Query: 914 REVISTLLEK---MKIDKRNYQIGKTK-VFLKETERQALQETLHREVVR--KILLLQSWF 967 R +T+++K M + +R Y+I + + L+ R L +R+++R K +++Q Sbjct: 814 RTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRV 873 Query: 968 RMVLERRHFLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYWQRKLYRHQKQS 1027 R L R H+ + A + +Q C+R +R L++ + + +KL+ + Sbjct: 874 RGWLARTHYKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERY-----KKLHIGMENK 928 Query: 1028 IIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAARAGAEEGGQGQAAGG 1080 I++LQ + Q K + ++ + E EK R LE + EE + A G Sbjct: 929 IMQLQR--KVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEE---AKVATG 983 Query: 1081 QQVAEQGPEPAEDGGHLASEPEVQPSDRSPL-EHSSPEKEAP-------SPEKTLPPQKT 1132 + ++ Q E+ L + E S++ + EH+ K+ E TL Q+ Sbjct: 984 RVLSLQ-----EEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEK 1038 Query: 1133 VAAESHEKVPSSREKRESRRQRGLEHVKFQNKHI--QSCKEESALREPSRRVTQEQGVSL 1190 A +H V ++E E+ ++ +E K + + + ++ L E SR Sbjct: 1039 EAL-NHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSR---------- 1087 Query: 1191 LEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETE-KTLPSGSPRPGQLE 1249 LE++ + ++E L+V + T SE E + +PS + P + + Sbjct: 1088 LEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKK 1147 Query: 1250 RPTSLAL 1256 P ++L Sbjct: 1148 VPLDMSL 1154 >gi|153945715 myosin VC [Homo sapiens] Length = 1742 Score = 379 bits (973), Expect = e-104 Identities = 215/520 (41%), Positives = 304/520 (58%), Gaps = 10/520 (1%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQK-IYTYAGSILVAINPFKFLPIYNPKYVKMYENQQ 207 +DL L L E +L NL+ RF + K IYTY+G ILVA+NP+K LPIY + Y Q Sbjct: 70 NDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYGDAIIHAYSGQN 129 Query: 208 LGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYASG 267 +G ++PH+FA+A+ AY M R NQ I++SGESG+GKT S + + +S+ G + Sbjct: 130 MGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYFATVSKSGSNAH 189 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 VE +L + P+ EA GNAKT N+NSSRFGK+ ++S+ E + GA + YLLEKSR+V Sbjct: 190 VEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANMSTYLLEKSRVVF 249 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 Q ++ERNYH+FY L + E + +L E++ Y + +G + + + ++ Sbjct: 250 QSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGVNDRAEMVETQKT 309 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKRE 447 ++GF + +F +L+AIL+LGNV + A G E L +LL ++ Sbjct: 310 FTLLGFKEDFQMDVFKILAAILHLGNV--QITAVGNERSSVSEDDSHLKVFCELLGLESG 367 Query: 448 ILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDV 507 + + L RK VT ++ ++ P + +A+ ARD++AK +Y+ LFD+IV RIN AL Sbjct: 368 RVAQWLCNRKIVTSSETVVKPMTRPQAVNARDALAKKIYAHLFDFIVERINQAL-----Q 422 Query: 508 EEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITW 567 IGVLDI+GFE F+ NSFEQFCINYANE+LQ FN H+FKLEQEEY E I W Sbjct: 423 FSGKQHTFIGVLDIYGFETFDVNSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKEDIPW 482 Query: 568 HNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVM 627 I + DN I LI K G+ LLDEE PH T + L K + P M Sbjct: 483 TLIDFYDNQPVIDLIEAK-MGILELLDEECLLPHGTDENWLQKLYNNFVNRNPLFEKPRM 541 Query: 628 -EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGS 666 +F+IQHFA KV+Y+ + F EKN D + +V +LR S Sbjct: 542 SNTSFVIQHFADKVEYKCEGFLEKNRDTVYDMLVEILRAS 581 Score = 134 bits (338), Expect = 7e-31 Identities = 76/250 (30%), Positives = 139/250 (55%), Gaps = 9/250 (3%) Query: 810 RTTKSLLHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELV 869 ++ K ++ + K ++ ++F++SL L+E L P ++RCI+ N EK FD + + Sbjct: 607 KSAKQVIKPNSKHFRTTVGSKFRSSLYLLMETLNATTPHYVRCIKPNDEKLPFEFDSKRI 666 Query: 870 LQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVLLPKDA---QPCREVISTLLEKMKI 926 +QQLR G+LET+RI Y +++T+ +F ++ +L+ K +EV +L ++ Sbjct: 667 VQQLRACGVLETIRISAQSYPSRWTYIEFYSRYGILMTKQELSFSDKKEVCKVVLHRLIQ 726 Query: 927 DKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTI 986 D YQ GKTK+F + + L++ ++ + +++Q R L+R+ FL+ +RAA+ I Sbjct: 727 DSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALII 786 Query: 987 QACWRSYRVRR------ALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQ 1040 Q +R + R AL+ AA+ +Q RGY R LY+ + + I +Q+ RG L Sbjct: 787 QQYFRGQQTVRKAITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLA 846 Query: 1041 RKSFSQMISE 1050 R+ + +M+ E Sbjct: 847 RRRYRKMLEE 856 >gi|92859701 myosin VI [Homo sapiens] Length = 1285 Score = 367 bits (943), Expect = e-101 Identities = 220/572 (38%), Positives = 326/572 (56%), Gaps = 53/572 (9%) Query: 147 DFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLP-IYNPKYVKMYEN 205 D +D C+L L E LL N+K R+ + +IYTY +IL+A+NP+ +P IY+ + +K Y+ Sbjct: 58 DVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQG 117 Query: 206 QQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGYA 265 + LG PHVFA+AD A+ M +++Q I++SGESG+GKT++T F++ LT G Sbjct: 118 KSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLT--ESYGTG 175 Query: 266 SGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRL 325 ++ I+ A P+LEAFGNAKT NNNSSRFGKF+++ + E V G V YLLEKSR+ Sbjct: 176 QDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRI 235 Query: 326 VSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNL-----KIEDGEDLKH- 379 Q K+ERNYH+FY L G SE+ R++ L P+++ YLN+ K D + L++ Sbjct: 236 CVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNR 295 Query: 380 --------------------DFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR 419 DF R+ AM+ +G K +F V++ +L+LGN+ +++ Sbjct: 296 KSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEA 355 Query: 420 -ATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTV-----NDKLILPYSLSE 473 +T L+ + L+ ++LL + ++ L LT R +T + +P + + Sbjct: 356 GSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQ 415 Query: 474 AITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFE 533 A ARD++AK++YS LFD +V R+N + S IGVLDI GFE FE NSFE Sbjct: 416 ANNARDALAKTVYSHLFDHVVNRVNQCFPFE------TSSYFIGVLDIAGFEYFEHNSFE 469 Query: 534 QFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLL 593 QFCINY NE+LQ +FN+ I K EQE YQ EG+ + + Y DN CI LI K G+ +L Sbjct: 470 QFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDIL 529 Query: 594 DEESNFPHATSQTLLAKFKQQHEDNKYFLGTPVM-----------EPAFIIQHFAGKVKY 642 DEE+ P + Q + Q+H+D+ + L P + FII+HFAG V Y Sbjct: 530 DEENRLPQPSDQHFTSAVHQKHKDH-FRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCY 588 Query: 643 QIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674 + F EKN D + + +L+ S ++REL Sbjct: 589 ETTQFVEKNNDALHMSLESLICESRDKFIREL 620 Score = 68.6 bits (166), Expect = 6e-11 Identities = 82/405 (20%), Positives = 174/405 (42%), Gaps = 49/405 (12%) Query: 826 SISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIR 885 S+ +F+T LN LL+ L FIRCI+ N + F+ +L QL+ +GM+ + + Sbjct: 642 SVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLM 701 Query: 886 RSGYSAKYTFQDFTEQFQVLLPKDAQPC--REVISTLLEKMKIDKRNYQIGKTKVFLKET 943 + GY ++ +F + ++ +P R L + + +++ +Y+ G TKVF + Sbjct: 702 QGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPG 761 Query: 944 ERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRS-YRVRRALE-R 1001 + + + + +V H+L R +Q C S +++ ++ R Sbjct: 762 KFAEFDQIMKSDP-------DHLAELVKRVNHWLTCSRWK-KVQWCSLSVIKLKNKIKYR 813 Query: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREA 1061 +A + +Q + R + ++ ++ + ++++ +L +K +K E Sbjct: 814 AEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTL-----------------KKRLDKFNEV 856 Query: 1062 LEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAP 1121 + + G E +Q+ + E + D + + ++ E+ + K + Sbjct: 857 VSVLKDGKPE-------MNKQI--KNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSE 907 Query: 1122 SPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALR-EPSR 1180 L +K E+ E++ +E+ E R+R E K + K +EE ++ E Sbjct: 908 ELLSALQKKKQQEEEA-ERLRRIQEEMEKERKRREEDEKRRRKE----EEERRMKLEMEA 962 Query: 1181 RVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAM 1225 + QE+ E++K+ +DE + E EA+ QK+ Q QA+ Sbjct: 963 KRKQEE-----EERKKREDDEKRIQAEVEAQLARQKEEESQQQAV 1002 >gi|27544941 myosin IF [Homo sapiens] Length = 1098 Score = 367 bits (942), Expect = e-101 Identities = 209/544 (38%), Positives = 323/544 (59%), Gaps = 28/544 (5%) Query: 144 QQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMY 203 +Q+ DD+ LP++TE + NL+ RF+ I+TY GS+L+++NPFK +P + + + +Y Sbjct: 15 KQSGVDDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY 74 Query: 204 ENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG 263 + + PH++AL D Y ML NQC++ISGESG+GKT + +++ ++ +S G Sbjct: 75 QGAAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGG 134 Query: 264 Y-ASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEK 322 V+ IL + P+LEAFGNAKT NNNSSRFGK+ ++ + G G + +LLEK Sbjct: 135 EKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEK 194 Query: 323 SRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDLKHDFE 382 SR+V Q ++ERN+H++Y LL G S+E+RQ L P+ Y+YLNQ + DG D + DF Sbjct: 195 SRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDGTDDRSDFG 254 Query: 383 RLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEG--LEVGPPEVLDTLSQ 440 AM+++G P+ ++ + +++ IL+LGN+++ E+G V ++L + Sbjct: 255 ETLSAMQVIGIPPSIQQLVLQLVAGILHLGNISF------CEDGNYARVESVDLLAFPAY 308 Query: 441 LLKVKREILVEVLTKRKTVT----VNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLR 496 LL + L E LT RK + ++ + + ++ +A RD++AK LY+ LFD++V Sbjct: 309 LLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLVEA 368 Query: 497 INHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLE 556 IN A+ +K EE SIGVLDI+GFE F++N FEQFCIN+ NE+LQ F + K E Sbjct: 369 INRAM--QKPQEE----YSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAE 422 Query: 557 QEEYQGEGITWHNIGYTDNVGCIHLISKK--PTGLFYLLDEESNFPHAT----SQTLLAK 610 QEEY EGI W I Y +N LI K P G+ +LD+ HAT QTLL K Sbjct: 423 QEEYVQEGIRWTPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLLQK 482 Query: 611 FKQQHEDNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSY 670 + +++F F+I H+AGKV Y + F E+N D + D++ L++ S+ ++ Sbjct: 483 LQAAVGTHEHFNS---WSAGFVIHHYAGKVSYDVSGFCERNRDVLFSDLIELMQTSEQAF 539 Query: 671 VREL 674 +R L Sbjct: 540 LRML 543 Score = 80.5 bits (197), Expect = 2e-14 Identities = 52/194 (26%), Positives = 96/194 (49%), Gaps = 6/194 (3%) Query: 820 KKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGML 879 KK +P + ++ + N L+ L + P +IRCI+ N K+ +++ V Q+ Y G+ Sbjct: 552 KKGRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRPRDWEENRVKHQVEYLGLK 611 Query: 880 ETVRIRRSGYSAKYTFQDFTEQFQVLLPKD----AQPCREVISTLLEKMKIDKRNYQIGK 935 E +R+RR+G++ + F F +++ +L P+ R+ + LL + ++ YQ+G Sbjct: 612 ENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGVQHLLRAVNMEPDQYQMGS 671 Query: 936 TKVFLKETERQ-ALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYR 994 TKVF+K E L+E R+ +Q +R + R + +M+ A I + R Sbjct: 672 TKVFVKNPESLFLLEEVRERKFDGFARTIQKAWRRHVAVRKYEEMREEASNI-LLNKKER 730 Query: 995 VRRALERTQAAVYL 1008 R ++ R YL Sbjct: 731 RRNSINRNFVGDYL 744 >gi|194328685 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 363 bits (932), Expect = e-99 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%) Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209 D+ L L E + NLK RF +IYTY GS+++++NP++ LPIY+P+ V+ Y N+ Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78 Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268 +L PH+FAL+D AY ++ + +QCI+I+GESG+GKT+++ ++ + A+ KG + V Sbjct: 79 ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 + +L + PVLEAFGNAKT N+NSSRFGK++ + + G G V+ YLLEKSR+V Q Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 + ERN+HVFY LL G SEE + +L++ Y YL+ + K+ +G D +F ++ A Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445 M++VGF+ + + AV++A+L LGN+ +K R G +E ++ L + +L + Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316 Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505 + +L + R +K+ ++++A ARD++AK+LYS LF W+V RIN ++ + Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376 Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565 V + V +GVLDI+GFE FE NSFEQF INY NE+LQ F + K EQEEY E I Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617 W +I Y +N LI G+ +LDEE P T +T L K Q QH + Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673 +++ T + F IQH+AGKV YQ++ F +KN D + D+ + + + ++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 674 L 674 L Sbjct: 553 L 553 Score = 118 bits (295), Expect = 7e-26 Identities = 73/253 (28%), Positives = 138/253 (54%), Gaps = 15/253 (5%) Query: 822 KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881 K+PP+ +QF+ S+ L++ L P +IRCI+ N +K F++ LV Q+RY G+LE Sbjct: 565 KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624 Query: 882 VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937 VR+RR+GY+ + ++ E++++L P P R + L +++I Y G++K Sbjct: 625 VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684 Query: 938 VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996 +F++ E L ++ + + L+Q +R R HFL MK++ + I A +R Y + Sbjct: 685 IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744 Query: 997 RALERTQ-AAVYLQASWRGYWQRKLYR---HQ---KQSIIRLQSLCRGHLQRKSFSQMIS 1049 + ++T+ +A+ +Q+ RG+ RK+ R HQ K+++ + + G R+ ++ Sbjct: 745 KRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRL-- 802 Query: 1050 EKQKAEEKEREAL 1062 K++A K A+ Sbjct: 803 -KEEARNKHAIAV 814 >gi|44889481 myosin IB isoform 2 [Homo sapiens] Length = 1078 Score = 363 bits (932), Expect = e-99 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%) Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209 D+ L L E + NLK RF +IYTY GS+++++NP++ LPIY+P+ V+ Y N+ Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78 Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268 +L PH+FAL+D AY ++ + +QCI+I+GESG+GKT+++ ++ + A+ KG + V Sbjct: 79 ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 + +L + PVLEAFGNAKT N+NSSRFGK++ + + G G V+ YLLEKSR+V Q Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 + ERN+HVFY LL G SEE + +L++ Y YL+ + K+ +G D +F ++ A Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445 M++VGF+ + + AV++A+L LGN+ +K R G +E ++ L + +L + Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316 Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505 + +L + R +K+ ++++A ARD++AK+LYS LF W+V RIN ++ + Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376 Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565 V + V +GVLDI+GFE FE NSFEQF INY NE+LQ F + K EQEEY E I Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617 W +I Y +N LI G+ +LDEE P T +T L K Q QH + Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673 +++ T + F IQH+AGKV YQ++ F +KN D + D+ + + + ++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 674 L 674 L Sbjct: 553 L 553 Score = 117 bits (293), Expect = 1e-25 Identities = 67/214 (31%), Positives = 122/214 (57%), Gaps = 9/214 (4%) Query: 822 KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881 K+PP+ +QF+ S+ L++ L P +IRCI+ N +K F++ LV Q+RY G+LE Sbjct: 565 KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624 Query: 882 VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937 VR+RR+GY+ + ++ E++++L P P R + L +++I Y G++K Sbjct: 625 VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684 Query: 938 VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996 +F++ E L ++ + + L+Q +R R HFL MK++ + I A +R Y + Sbjct: 685 IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744 Query: 997 RALERTQ-AAVYLQASWRGYWQRKLYR---HQKQ 1026 + ++T+ +A+ +Q+ RG+ RK+ R HQK+ Sbjct: 745 KRYQQTKSSALVIQSYIRGWKARKILRELKHQKR 778 >gi|240120050 myosin IB isoform 1 [Homo sapiens] Length = 1136 Score = 363 bits (932), Expect = e-99 Identities = 209/541 (38%), Positives = 322/541 (59%), Gaps = 22/541 (4%) Query: 150 DLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLG 209 D+ L L E + NLK RF +IYTY GS+++++NP++ LPIY+P+ V+ Y N+ Sbjct: 19 DMVLLEPLNEETFINNLKKRFDHSEIYTYIGSVVISVNPYRSLPIYSPEKVEEYRNRNFY 78 Query: 210 KLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASGV 268 +L PH+FAL+D AY ++ + +QCI+I+GESG+GKT+++ ++ + A+ KG + V Sbjct: 79 ELSPHIFALSDEAYRSLRDQDKDQCILITGESGAGKTEASKLVMSYVAAVCGKGAEVNQV 138 Query: 269 ERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQ 328 + +L + PVLEAFGNAKT N+NSSRFGK++ + + G G V+ YLLEKSR+V Q Sbjct: 139 KEQLLQSNPVLEAFGNAKTVRNDNSSRFGKYMDIEFDFKGDPLGGVISNYLLEKSRVVKQ 198 Query: 329 EKDERNYHVFYYLLLGVSEEERQEFQLKQP-EDYFYLNQHNLKIEDGEDLKHDFERLKQA 387 + ERN+HVFY LL G SEE + +L++ Y YL+ + K+ +G D +F ++ A Sbjct: 199 PRGERNFHVFYQLLSGASEELLNKLKLERDFSRYNYLSLDSAKV-NGVDDAANFRTVRNA 257 Query: 388 MEMVGFLPATKKQIFAVLSAILYLGNVTYK--KRATGREEGLEVGPPEVLDTLSQLLKVK 445 M++VGF+ + + AV++A+L LGN+ +K R G +E ++ L + +L + Sbjct: 258 MQIVGFMDHEAESVLAVVAAVLKLGNIEFKPESRVNGLDES-KIKDKNELKEICELTGID 316 Query: 446 REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALLNKK 505 + +L + R +K+ ++++A ARD++AK+LYS LF W+V RIN ++ + Sbjct: 317 QSVLERAFSFRTVEAKQEKVSTTLNVAQAYYARDALAKNLYSRLFSWLVNRINESIKAQT 376 Query: 506 DVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGI 565 V + V +GVLDI+GFE FE NSFEQF INY NE+LQ F + K EQEEY E I Sbjct: 377 KVRKKV----MGVLDIYGFEIFEDNSFEQFIINYCNEKLQQIFIELTLKEEQEEYIREDI 432 Query: 566 TWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFP-HATSQTLLAKFKQ-----QHED-- 617 W +I Y +N LI G+ +LDEE P T +T L K Q QH + Sbjct: 433 EWTHIDYFNNAIICDLIENNTNGILAMLDEECLRPGTVTDETFLEKLNQVCATHQHFESR 492 Query: 618 ----NKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVRE 673 +++ T + F IQH+AGKV YQ++ F +KN D + D+ + + + ++ Sbjct: 493 MSKCSRFLNDTSLPHSCFRIQHYAGKVLYQVEGFVDKNNDLLYRDLSQAMWKASHALIKS 552 Query: 674 L 674 L Sbjct: 553 L 553 Score = 118 bits (295), Expect = 7e-26 Identities = 73/253 (28%), Positives = 138/253 (54%), Gaps = 15/253 (5%) Query: 822 KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881 K+PP+ +QF+ S+ L++ L P +IRCI+ N +K F++ LV Q+RY G+LE Sbjct: 565 KRPPTAGSQFKASVATLMKNLQTKNPNYIRCIKPNDKKAAHIFNEALVCHQIRYLGLLEN 624 Query: 882 VRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNYQIGKTK 937 VR+RR+GY+ + ++ E++++L P P R + L +++I Y G++K Sbjct: 625 VRVRRAGYAFRQAYEPCLERYKMLCKQTWPHWKGPARSGVEVLFNELEIPVEEYSFGRSK 684 Query: 938 VFLKETERQALQETLHREVVRKI-LLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996 +F++ E L ++ + + L+Q +R R HFL MK++ + I A +R Y + Sbjct: 685 IFIRNPRTLFKLEDLRKQRLEDLATLIQKIYRGWKCRTHFLLMKKSQIVIAAWYRRYAQQ 744 Query: 997 RALERTQ-AAVYLQASWRGYWQRKLYR---HQ---KQSIIRLQSLCRGHLQRKSFSQMIS 1049 + ++T+ +A+ +Q+ RG+ RK+ R HQ K+++ + + G R+ ++ Sbjct: 745 KRYQQTKSSALVIQSYIRGWKARKILRELKHQKRCKEAVTTIAAYWHGTQARRELRRL-- 802 Query: 1050 EKQKAEEKEREAL 1062 K++A K A+ Sbjct: 803 -KEEARNKHAIAV 814 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 361 bits (927), Expect = 4e-99 Identities = 223/588 (37%), Positives = 331/588 (56%), Gaps = 26/588 (4%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NLK R+ IYTY+G V INP+K LPIY+ + V+ Sbjct: 77 PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTN----FLIHCLT 257 MY+ ++ ++ PH++A+ D AY +M++ R +Q I+ +GESG+GKT++T +L + + Sbjct: 137 MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196 Query: 258 ALSQKGYASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEK 317 + K +ER +L A P+LEAFGNAKT N+NSSRFGKFI++++ +G + GA +E Sbjct: 197 SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256 Query: 318 YLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDGEDL 377 YLLEKSR + Q K+ER +H+FYYLL G E + + L+ Y +L+ ++ I +D Sbjct: 257 YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQD- 315 Query: 378 KHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDT 437 K F+ +AM ++G + + V+S +L LGN+ +KK + + Sbjct: 316 KDMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKERNTDQASMP--DNTAAQK 373 Query: 438 LSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLR 496 +S LL + + +LT R V D + + +A A +++AK+ Y +F W+VLR Sbjct: 374 VSHLLGINVTDFTRGILTPRIKVG-RDYVQKAQTKEQADFAIEALAKATYERMFRWLVLR 432 Query: 497 INHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLE 556 IN AL D + IG+LDI GFE F+ NSFEQ CINY NE+LQ FN +F LE Sbjct: 433 INKAL----DKTKRQGASFIGILDIAGFEIFDLNSFEQLCINYTNEKLQQLFNHTMFILE 488 Query: 557 QEEYQGEGITWHNIGY-TDNVGCIHLISKK--PTGLFYLLDEESNFPHATSQTLLAKFKQ 613 QEEYQ EGI W+ I + D CI LI K P G+ LLDEE FP AT ++ + K Q Sbjct: 489 QEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPKATDKSFVEKVMQ 548 Query: 614 QHEDNKYFLGTPVMEPA--FIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYV 671 + + F ++ F I H+AGKV Y+ ++ KNMD + +I LL S +V Sbjct: 549 EQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLHQSSDKFV 608 Query: 672 REL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 EL IG+D VA L A + + R G+L E+ K Sbjct: 609 SELWKDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAK 656 Score = 101 bits (251), Expect = 9e-21 Identities = 94/420 (22%), Positives = 183/420 (43%), Gaps = 57/420 (13%) Query: 826 SISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIR 885 ++ ++ L KL+ L P F+RCI N EKK D LVL QLR G+LE +RI Sbjct: 645 TVGQLYKEQLAKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRIC 704 Query: 886 RSGYSAKYTFQDFTEQFQVL----LPKDAQPCREVISTLLEKMKIDKRNYQIGKTKVFLK 941 R G+ + FQ+F +++++L +PK ++ +++ +++D Y+IG++KVF + Sbjct: 705 RQGFPNRVVFQEFRQRYEILTPNSIPKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFR 764 Query: 942 ETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRALER 1001 L+E ++ I+ Q+ R L R+ F + ++ + + L+R Sbjct: 765 AGVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAM----------KVLQR 814 Query: 1002 TQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAEEKEREA 1061 AA +W+ +W +L+ K + + R+ M E++ + +E++ Sbjct: 815 NCAAYLKLRNWQ-WW--RLFTKVKPLL---------QVSRQEEEMMAKEEELVKVREKQL 862 Query: 1062 LEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKEAP 1121 R E Q Q +A + ++Q E E E Sbjct: 863 AAENRLTEMETLQSQL-------------------MAEKLQLQ-------EQLQAETELC 896 Query: 1122 SPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNK----HIQSCKEESALRE 1177 + + L + T + E++ E R + +H++ + K +IQ +E+ E Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956 Query: 1178 PSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEETEKT 1237 +R+ Q + V+ E K + E+E +++ + + +K+ E A ++EE EK+ Sbjct: 957 SARQKLQLEKVT-TEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKS 1015 Score = 34.3 bits (77), Expect = 1.4 Identities = 39/173 (22%), Positives = 75/173 (43%), Gaps = 7/173 (4%) Query: 1032 QSLCRGHLQRKSFSQMISEKQKAEEK---EREALEAARAGAEEGGQGQAAGGQQVAEQGP 1088 QS C ++K F Q+++E++ K ER+ EA E A ++ EQ Sbjct: 1434 QSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKA 1493 Query: 1089 EPAEDGGHLASEPEVQPSDRSPLEHS--SPEKEAPSPEKTLPPQKTVAAESHEKVPSSRE 1146 E +E E S + + S EK + E+ + KT E +++ ++ E Sbjct: 1494 ELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQAT-E 1552 Query: 1147 KRESRRQRGLEHVKFQNKHIQSCKEESALREPSRRVTQEQGVSL-LEDKKESR 1198 + R + L+ +K Q + ++E + + + V Q + + LED+++ R Sbjct: 1553 DAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQR 1605 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 354 bits (908), Expect = 6e-97 Identities = 218/591 (36%), Positives = 331/591 (56%), Gaps = 29/591 (4%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NL+ R+ IYTY+G V +NP+K LPIY+ K V Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259 MY+ ++ ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T +I L A Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200 Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314 S KG +E+ +L A P+LEAFGNAKT N+NSSRFGKFI++++ +G + GA Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260 Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374 +E YLLEKSR + Q +DER +H+FYY++ G E+ R + L+ +Y +L+ + I Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320 Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV 434 +D F+ +AM ++GF + I V+S++L LGN+ +KK + + Sbjct: 321 QD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMP--DNTA 377 Query: 435 LDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWI 493 + L+ + + +LT R V D + + +A A +++AK+ Y LF WI Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATYERLFRWI 436 Query: 494 VLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIF 553 + R+N AL D +G+LDI GFE FE NSFEQ CINY NE+LQ FN +F Sbjct: 437 LTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMF 492 Query: 554 KLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLLAK 610 LEQEEYQ EGI W+ I + D CI LI + P G+ LLDEE FP AT ++ + K Sbjct: 493 ILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEK 552 Query: 611 FKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDS 668 + + F + + F I H+AGKV Y + KNMD + ++ +LL S Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612 Query: 669 SYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 +V +L +G+D +A + L +A + + R G+L E+ K Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 663 Score = 97.1 bits (240), Expect = 2e-19 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%) Query: 797 KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853 K + I+ + + T+S L K K ++ ++ L KL+ L P F+RCI Sbjct: 620 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679 Query: 854 RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909 N EK+ D LVL+QLR G+LE +RI R G+ + FQ+F +++++L +PK Sbjct: 680 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739 Query: 910 AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969 ++ +++ +++D Y+IG++K+F + L+E ++ I+ Q+ R Sbjct: 740 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799 Query: 970 VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013 L R+ F + ++ ++ WR + +V+ L+ T+ +QA + Sbjct: 800 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 857 Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066 +K Q+++ L+ L + H Q ++ E+ +AE E+ R L A + Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917 Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119 EE + + GQQ+ + + A+ L + E + + R L+ E Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977 Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179 A K L + V + + K+ R+ E R ++ + + K + L+ Sbjct: 978 AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1032 Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234 + E V L +++K +E E L +E +A + ++ Q Q M + K EE Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092 Query: 1235 EKTL 1238 + L Sbjct: 1093 QAAL 1096 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 354 bits (908), Expect = 6e-97 Identities = 218/591 (36%), Positives = 331/591 (56%), Gaps = 29/591 (4%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NL+ R+ IYTY+G V +NP+K LPIY+ K V Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259 MY+ ++ ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T +I L A Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200 Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314 S KG +E+ +L A P+LEAFGNAKT N+NSSRFGKFI++++ +G + GA Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260 Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374 +E YLLEKSR + Q +DER +H+FYY++ G E+ R + L+ +Y +L+ + I Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320 Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEV 434 +D F+ +AM ++GF + I V+S++L LGN+ +KK + + Sbjct: 321 QD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMP--DNTA 377 Query: 435 LDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWI 493 + L+ + + +LT R V D + + +A A +++AK+ Y LF WI Sbjct: 378 AQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATYERLFRWI 436 Query: 494 VLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIF 553 + R+N AL D +G+LDI GFE FE NSFEQ CINY NE+LQ FN +F Sbjct: 437 LTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMF 492 Query: 554 KLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLLAK 610 LEQEEYQ EGI W+ I + D CI LI + P G+ LLDEE FP AT ++ + K Sbjct: 493 ILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEK 552 Query: 611 FKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDS 668 + + F + + F I H+AGKV Y + KNMD + ++ +LL S Sbjct: 553 LCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSD 612 Query: 669 SYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 +V +L +G+D +A + L +A + + R G+L E+ K Sbjct: 613 KFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 663 Score = 97.1 bits (240), Expect = 2e-19 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%) Query: 797 KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853 K + I+ + + T+S L K K ++ ++ L KL+ L P F+RCI Sbjct: 620 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679 Query: 854 RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909 N EK+ D LVL+QLR G+LE +RI R G+ + FQ+F +++++L +PK Sbjct: 680 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 739 Query: 910 AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969 ++ +++ +++D Y+IG++K+F + L+E ++ I+ Q+ R Sbjct: 740 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 799 Query: 970 VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013 L R+ F + ++ ++ WR + +V+ L+ T+ +QA + Sbjct: 800 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 857 Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066 +K Q+++ L+ L + H Q ++ E+ +AE E+ R L A + Sbjct: 858 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 917 Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119 EE + + GQQ+ + + A+ L + E + + R L+ E Sbjct: 918 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 977 Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179 A K L + V + + K+ R+ E R ++ + + K + L+ Sbjct: 978 AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1032 Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234 + E V L +++K +E E L +E +A + ++ Q Q M + K EE Sbjct: 1033 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1092 Query: 1235 EKTL 1238 + L Sbjct: 1093 QAAL 1096 >gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] Length = 1976 Score = 353 bits (907), Expect = 8e-97 Identities = 227/593 (38%), Positives = 330/593 (55%), Gaps = 33/593 (5%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NLK R+ IYTY+G V INP+K LPIY+ ++ Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENIIE 140 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259 MY ++ ++ PH++A+++ AY ML+ R +Q I+ +GESG+GKT++T +I L A Sbjct: 141 MYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVAS 200 Query: 260 SQKG-----YASGVERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAV 314 S KG +ER +L A P+LE+FGNAKT N+NSSRFGKFI++++ +G + GA Sbjct: 201 SHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260 Query: 315 VEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQHNLKIEDG 374 +E YLLEKSR V Q KDER +H+FY LL G E + + L+ +Y +L+ + I Sbjct: 261 IETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPGQ 320 Query: 375 EDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPE- 433 +D K +F+ +AM ++GF + V+S++L GN+++KK + + PE Sbjct: 321 QD-KDNFQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKERNTDQASM----PEN 375 Query: 434 -VLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFD 491 V L LL + E +LT R V D + + +A A +++AK+ Y LF Sbjct: 376 TVAQKLCHLLGMNVMEFTRAILTPRIKVG-RDYVQKAQTKEQADFAVEALAKATYERLFR 434 Query: 492 WIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQH 551 W+V RIN AL D + IG+LDI GFE FE NSFEQ CINY NE+LQ FN Sbjct: 435 WLVHRINKAL----DRTKRQGASFIGILDIAGFEIFELNSFEQLCINYTNEKLQQLFNHT 490 Query: 552 IFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHATSQTLL 608 +F LEQEEYQ EGI W+ I + D CI LI + P G+ LLDEE FP AT +T + Sbjct: 491 MFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPGVLALLDEECWFPKATDKTFV 550 Query: 609 AKFKQQHEDNKYFLGTPVMEPA--FIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGS 666 K Q+ + F ++ F I H+AGKV Y+ ++ KNMD + ++ LL S Sbjct: 551 EKLVQEQGSHSKFQKPRQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNVATLLHQS 610 Query: 667 DSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 +V EL +G+D V +A + + R G+L E K Sbjct: 611 SDRFVAELWKDVDRIVGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLTK 663 Score = 106 bits (264), Expect = 3e-22 Identities = 107/422 (25%), Positives = 180/422 (42%), Gaps = 51/422 (12%) Query: 820 KKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGML 879 KK ++ ++ SL KL+ L P F+RCI N EK+ D LVL QLR G+L Sbjct: 646 KKGMFRTVGQLYKESLTKLMATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVL 705 Query: 880 ETVRIRRSGYSAKYTFQDFTEQFQVL----LPKDAQPCREVISTLLEKMKIDKRNYQIGK 935 E +RI R G+ + FQ+F +++++L +PK ++ ++ +++D Y+IG+ Sbjct: 706 EGIRICRQGFPNRIVFQEFRQRYEILTPNAIPKGFMDGKQACERMIRALELDPNLYRIGQ 765 Query: 936 TKVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRV 995 +K+F + L+E ++ I+ Q+ R L R+ F + ++ + Sbjct: 766 SKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSAL--------- 816 Query: 996 RRALERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQM-ISEKQKA 1054 + L+R AA W+ W R + + + Q LQ K + + EKQ Sbjct: 817 -KVLQRNCAAYLKLRHWQ--WWRVFTKVKPLLQVTRQ---EEELQAKDEELLKVKEKQTK 870 Query: 1055 EEKEREALEAARAGAEEGGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHS 1114 E E E +E QQ+ E+ AE L +E E+ Sbjct: 871 VEGELEEMERKH--------------QQLLEEKNILAE---QLQAETEL----------- 902 Query: 1115 SPEKEAPSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESA 1174 EA L +K E + S E+ E R Q K HIQ +E+ Sbjct: 903 --FAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960 Query: 1175 LREPSRRVTQEQGVSLLEDKKESREDETLLVVETEAENTSQKQPTEQPQAMAVGKVSEET 1234 E +R+ Q + V+ E K + E+E LL+ + ++ +K+ E A +++EE Sbjct: 961 EEEGARQKLQLEKVT-AEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEE 1019 Query: 1235 EK 1236 EK Sbjct: 1020 EK 1021 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 352 bits (904), Expect = 2e-96 Identities = 220/598 (36%), Positives = 334/598 (55%), Gaps = 36/598 (6%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NL+ R+ IYTY+G V +NP+K LPIY+ K V Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259 MY+ ++ ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T +I L A Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200 Query: 260 SQKG-----------YASG-VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLES 307 S KG +A G +E+ +L A P+LEAFGNAKT N+NSSRFGKFI++++ + Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260 Query: 308 GIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQH 367 G + GA +E YLLEKSR + Q +DER +H+FYY++ G E+ R + L+ +Y +L+ Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320 Query: 368 NLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGL 427 + I +D F+ +AM ++GF + I V+S++L LGN+ +KK + + Sbjct: 321 FVPIPAAQD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM 379 Query: 428 EVGPPEVLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLY 486 + L+ + + +LT R V D + + +A A +++AK+ Y Sbjct: 380 P--DNTAAQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATY 436 Query: 487 SALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQY 546 LF WI+ R+N AL D +G+LDI GFE FE NSFEQ CINY NE+LQ Sbjct: 437 ERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 492 Query: 547 YFNQHIFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHAT 603 FN +F LEQEEYQ EGI W+ I + D CI LI + P G+ LLDEE FP AT Sbjct: 493 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT 552 Query: 604 SQTLLAKFKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVA 661 ++ + K + + F + + F I H+AGKV Y + KNMD + ++ + Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612 Query: 662 LLRGSDSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 LL S +V +L +G+D +A + L +A + + R G+L E+ K Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670 Score = 97.1 bits (240), Expect = 2e-19 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%) Query: 797 KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853 K + I+ + + T+S L K K ++ ++ L KL+ L P F+RCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 854 RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909 N EK+ D LVL+QLR G+LE +RI R G+ + FQ+F +++++L +PK Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 910 AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969 ++ +++ +++D Y+IG++K+F + L+E ++ I+ Q+ R Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 970 VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013 L R+ F + ++ ++ WR + +V+ L+ T+ +QA + Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 864 Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066 +K Q+++ L+ L + H Q ++ E+ +AE E+ R L A + Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924 Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119 EE + + GQQ+ + + A+ L + E + + R L+ E Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984 Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179 A K L + V + + K+ R+ E R ++ + + K + L+ Sbjct: 985 AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1039 Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234 + E V L +++K +E E L +E +A + ++ Q Q M + K EE Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099 Query: 1235 EKTL 1238 + L Sbjct: 1100 QAAL 1103 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 352 bits (904), Expect = 2e-96 Identities = 220/598 (36%), Positives = 334/598 (55%), Gaps = 36/598 (6%) Query: 142 PRQQADFDDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVK 201 P + + +D+ L L E ++L NL+ R+ IYTY+G V +NP+K LPIY+ K V Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140 Query: 202 MYENQQLGKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLT--AL 259 MY+ ++ ++ PH++A+AD AY +ML+ R +Q I+ +GESG+GKT++T +I L A Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200 Query: 260 SQKG-----------YASG-VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLES 307 S KG +A G +E+ +L A P+LEAFGNAKT N+NSSRFGKFI++++ + Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260 Query: 308 GIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLNQH 367 G + GA +E YLLEKSR + Q +DER +H+FYY++ G E+ R + L+ +Y +L+ Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320 Query: 368 NLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGL 427 + I +D F+ +AM ++GF + I V+S++L LGN+ +KK + + Sbjct: 321 FVPIPAAQD-DEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASM 379 Query: 428 EVGPPEVLDTLSQLLKVK-REILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLY 486 + L+ + + +LT R V D + + +A A +++AK+ Y Sbjct: 380 P--DNTAAQKVCHLMGINVTDFTRSILTPRIKVG-RDVVQKAQTKEQADFAVEALAKATY 436 Query: 487 SALFDWIVLRINHALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQY 546 LF WI+ R+N AL D +G+LDI GFE FE NSFEQ CINY NE+LQ Sbjct: 437 ERLFRWILTRVNKAL----DKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQ 492 Query: 547 YFNQHIFKLEQEEYQGEGITWHNIGY-TDNVGCIHLISK--KPTGLFYLLDEESNFPHAT 603 FN +F LEQEEYQ EGI W+ I + D CI LI + P G+ LLDEE FP AT Sbjct: 493 LFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKAT 552 Query: 604 SQTLLAKFKQQHEDNKYFLGTPVM--EPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVA 661 ++ + K + + F + + F I H+AGKV Y + KNMD + ++ + Sbjct: 553 DKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTS 612 Query: 662 LLRGSDSSYVREL-------IGMDPVAVFRWAVLRAAIRA-MAVLREAGRLRAERAEK 711 LL S +V +L +G+D +A + L +A + + R G+L E+ K Sbjct: 613 LLNASSDKFVADLWKDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGK 670 Score = 97.1 bits (240), Expect = 2e-19 Identities = 110/484 (22%), Positives = 210/484 (43%), Gaps = 49/484 (10%) Query: 797 KSLKLIISMTLHDRTTKSLLHLHKKKKPP---SISAQFQTSLNKLLEALGKAEPFFIRCI 853 K + I+ + + T+S L K K ++ ++ L KL+ L P F+RCI Sbjct: 627 KDVDRIVGLDQMAKMTESSLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCI 686 Query: 854 RSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQFQVL----LPKD 909 N EK+ D LVL+QLR G+LE +RI R G+ + FQ+F +++++L +PK Sbjct: 687 IPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG 746 Query: 910 AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILLLQSWFRM 969 ++ +++ +++D Y+IG++K+F + L+E ++ I+ Q+ R Sbjct: 747 FMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRG 806 Query: 970 VLERRHFLQMKRAAVTIQAC---------------WRSY-RVRRALERTQAAVYLQASWR 1013 L R+ F + ++ ++ WR + +V+ L+ T+ +QA + Sbjct: 807 YLARKAFAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQA--K 864 Query: 1014 GYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMISEKQKAE-------EKEREALEAAR 1066 +K Q+++ L+ L + H Q ++ E+ +AE E+ R L A + Sbjct: 865 EDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKK 924 Query: 1067 AGAEE-------GGQGQAAGGQQVAEQGPEPAEDGGHLASEPEVQPSDRSPLEHSSPEKE 1119 EE + + GQQ+ + + A+ L + E + + R L+ E Sbjct: 925 QELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAE 984 Query: 1120 APSPEKTLPPQKTVAAESHEKVPSSREKRESRRQRGLEHVKFQNKHIQSCKEESALREPS 1179 A K L + V + + K+ R+ E R ++ + + K + L+ Sbjct: 985 AKI--KKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEE---EKAKNLTKLKNKH 1039 Query: 1180 RRVTQEQGVSLLEDKKESREDETL-LVVETEAENTSQKQPTEQPQ----AMAVGKVSEET 1234 + E V L +++K +E E L +E +A + ++ Q Q M + K EE Sbjct: 1040 ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEEL 1099 Query: 1235 EKTL 1238 + L Sbjct: 1100 QAAL 1103 >gi|4885503 myosin IA [Homo sapiens] Length = 1043 Score = 351 bits (900), Expect = 5e-96 Identities = 209/547 (38%), Positives = 310/547 (56%), Gaps = 32/547 (5%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 +DL L L E +LLKNL+ R+ ++IYTY G++++++NP++ LPIY P+++ Y++ Sbjct: 11 EDLVLLEPLVEESLLKNLQLRYENKEIYTYIGNVVISVNPYQQLPIYGPEFIAKYQDYTF 70 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKG-YASG 267 +L+PH++ALA+VAY ++ + +QCI+I+GESGSGKT+++ ++ + A+ KG + Sbjct: 71 YELKPHIYALANVAYQSLRDRDRDQCILITGESGSGKTEASKLVMSYVAAVCGKGEQVNS 130 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 V+ +L + PVLEAFGNAKT NNNSSRFGK++ + + G G V+ YLLEKSRLV Sbjct: 131 VKEQLLQSNPVLEAFGNAKTIRNNNSSRFGKYMDIEFDFKGSPLGGVITNYLLEKSRLVK 190 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQL-KQPEDYFYLNQHNLKIEDGEDLKHDFERLKQ 386 Q K ERN+H+FY LL G E+ + +L + Y YLN H + DG D F ++ Sbjct: 191 QLKGERNFHIFYQLLAGADEQLLKALKLERDTTGYAYLN-HEVSRVDGMDDASSFRAVQS 249 Query: 387 AMEMVGFLPATKKQIFAVLSAILYLGNVTYKKR-------ATGREEGLEVGPPEVLDTLS 439 AM ++GF +Q+ V S +L LGNV A+G +G V + Sbjct: 250 AMAVIGFSEEEIRQVLEVTSMVLKLGNVLVADEFQASGIPASGIRDGRGV------REIG 303 Query: 440 QLLKVKREILVEVLTKRKTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINH 499 +++ + E + L R T +K++ ++ +A ARD++AK++YS LFDWIV RIN Sbjct: 304 EMVGLNSEEVERALCSRTMETAKEKVVTALNVMQAQYARDALAKNIYSRLFDWIVNRINE 363 Query: 500 ALLNKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEE 559 ++ K + E + GVLDI+GFE E NSFEQF INY NE+LQ F + K EQEE Sbjct: 364 SI--KVGIGEKKKVM--GVLDIYGFEILEDNSFEQFVINYCNEKLQQVFIEMTLKEEQEE 419 Query: 560 YQGEGITWHNIGYTDNVGCIHLISKKPTGLFYLLDEESNFPHATS-QTLLAKFKQQHEDN 618 Y+ EGI W + Y DN LI G+ +LDEE P S T LAK Q + Sbjct: 420 YKREGIPWTKVDYFDNGIICKLIEHNQRGILAMLDEECLRPGVVSDSTFLAKLNQLFSKH 479 Query: 619 KYFLGTPVME-----------PAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSD 667 ++ F I H+AGKV Y + F +KN D + D++ + + Sbjct: 480 GHYESKVTQNAQRQYDHTMGLSCFRICHYAGKVTYNVTSFIDKNNDLLFRDLLQAMWKAQ 539 Query: 668 SSYVREL 674 +R L Sbjct: 540 HPLLRSL 546 Score = 104 bits (260), Expect = 8e-22 Identities = 69/229 (30%), Positives = 118/229 (51%), Gaps = 29/229 (12%) Query: 822 KKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLET 881 K+PP+ AQF++S+ L++ L P +IRCI+ N ++ F +LV Q RY G+LE Sbjct: 558 KRPPTAGAQFKSSVAILMKNLYSKSPNYIRCIKPNEHQQRGQFSSDLVATQARYLGLLEN 617 Query: 882 VRIRRSGYSAKYTFQDFTEQFQVLLPKDAQPC-----REVISTLLEKMKIDKRNYQIGKT 936 VR+RR+GY+ + + F E+++ LL + P RE + +L ++ + GKT Sbjct: 618 VRVRRAGYAHRQGYGPFLERYR-LLSRSTWPHWNGGDREGVEKVLGELSMSSGELAFGKT 676 Query: 937 KVFLKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVR 996 K+F++ + TL LE + L++++ A IQ +R +R R Sbjct: 677 KIFIRSPK------TL----------------FYLEEQRRLRLQQLATLIQKIYRGWRCR 714 Query: 997 RALERTQAAVYLQASW-RGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSF 1044 + + + L +SW RG Q+K Y K S++ +Q+ RG RK++ Sbjct: 715 THYQLMRKSQILISSWFRGNMQKKCYGKIKASVLLIQAFVRGWKARKNY 763 >gi|55956916 myosin IE [Homo sapiens] Length = 1108 Score = 350 bits (899), Expect = 7e-96 Identities = 199/538 (36%), Positives = 321/538 (59%), Gaps = 26/538 (4%) Query: 149 DDLCNLPELTEGNLLKNLKHRFLQQKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQL 208 DD+ L ++TE ++++NLK R++ I+TY GS+L+++NPFK +P + K ++MY+ Sbjct: 22 DDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMYQGAAQ 81 Query: 209 GKLEPHVFALADVAYYTMLRKRVNQCIVISGESGSGKTQSTNFLIHCLTALSQKGY-ASG 267 + PH++ALAD Y M+ R NQC++ISGESG+GKT + +++ ++ +S G Sbjct: 82 YENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGGTKVQH 141 Query: 268 VERTILGAGPVLEAFGNAKTAHNNNSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVS 327 V+ IL + P+LEAFGNAKT NNNSSRFGK+ ++ + G G + +LLEKSR+V Sbjct: 142 VKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEPDGGKISNFLLEKSRVVM 201 Query: 328 QEKDERNYHVFYYLLLGVSEEERQEFQLKQPEDYFYLN-QHNLKIEDGEDLKHDFERLKQ 386 + ER++H+FY L+ G S E++ + + Y+YL+ + K++D +D + +F+ Sbjct: 202 RNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDIDD-RREFQETLH 260 Query: 387 AMEMVGFLPATKKQIFAVLSAILYLGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKR 446 AM ++G + + +++ IL+LGN+++K+ G +E E L + LL + + Sbjct: 261 AMNVIGIFAEEQTLVLQIVAGILHLGNISFKE--VGNYAAVE--SEEFLAFPAYLLGINQ 316 Query: 447 EILVEVLTKR----KTVTVNDKLILPYSLSEAITARDSMAKSLYSALFDWIVLRINHALL 502 + L E LT R K ++ + + ++ +A RD++AK+L++ +FD++V IN A+ Sbjct: 317 DRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFLVDSINKAM- 375 Query: 503 NKKDVEEAVSCLSIGVLDIFGFEDFERNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQG 562 +KD EE +IGVLDI+GFE F++N FEQFCIN+ NE+LQ F + K EQEEY Sbjct: 376 -EKDHEE----YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQ 430 Query: 563 EGITWHNIGYTDNVGCIHLISKK--PTGLFYLLDEESNFPHA----TSQTLLAKFKQQHE 616 EGI W I Y +N LI K P G+ +LD+ HA QTLL K + Q Sbjct: 431 EGIRWTPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTLLQKLQMQIG 490 Query: 617 DNKYFLGTPVMEPAFIIQHFAGKVKYQIKDFREKNMDYMRPDIVALLRGSDSSYVREL 674 +++F FII H+AGKV Y + F E+N D + D++ L++ S+ +++ L Sbjct: 491 SHEHFNS---WNQGFIIHHYAGKVSYDMDGFCERNRDVLFMDLIELMQSSELPFIKSL 545 Score = 90.1 bits (222), Expect = 2e-17 Identities = 50/173 (28%), Positives = 93/173 (53%), Gaps = 5/173 (2%) Query: 816 LHLHKKKKPPSISAQFQTSLNKLLEALGKAEPFFIRCIRSNAEKKELCFDDELVLQQLRY 875 L KK +P + ++ + N L+ L K P +IRCI+ N KK +++ V Q+ Y Sbjct: 550 LQADKKGRPTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKKPRDWEESRVKHQVEY 609 Query: 876 TGMLETVRIRRSGYSAKYTFQDFTEQFQVLL----PKDAQPCREVISTLLEKMKIDKRNY 931 G+ E +R+RR+GY+ + FQ F +++ +L P ++ + LL+ + +D + Sbjct: 610 LGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQGVLHLLQSVNMDSDQF 669 Query: 932 QIGKTKVFLKETERQ-ALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAA 983 Q+G++KVF+K E L+E R+ ++Q +R + R+ ++QM+ A Sbjct: 670 QLGRSKVFIKAPESLFLLEEMRERKYDGYARVIQKSWRKFVARKKYVQMREEA 722 >gi|124494238 myosin IC isoform a [Homo sapiens] Length = 1063 Score = 341 bits (874), Expect = 5e-93 Identities = 203/557 (36%), Positives = 313/557 (56%), Gaps = 23/557 (4%) Query: 118 IKYVH----MQLVAQATATRRLVERGLLPRQQADFDDLCNLPELT-EGNLLKNLKHRFLQ 172 I+ VH +L + R +E L R + D L T E ++NL+ RF + Sbjct: 14 IRVVHPHRPCKLALGSDGVRVTMESALTARDRVGVQDFVLLENFTSEAAFIENLRRRFRE 73 Query: 173 QKIYTYAGSILVAINPFKFLPIYNPKYVKMYENQQLGKLEPHVFALADVAYYTMLRKRVN 232 IYTY G +LV++NP++ L IY+ ++++ Y ++ PH+FA+AD Y + +R + Sbjct: 74 NLIYTYIGPVLVSVNPYRDLQIYSRQHMERYRGVSFYEVPPHLFAVADTVYRALRTERRD 133 Query: 233 QCIVISGESGSGKTQSTNFLIHCLTALSQKGYASGVERT-ILGAGPVLEAFGNAKTAHNN 291 Q ++ISGESG+GKT++T L+ G R +L + PVLEAFGNAKT N+ Sbjct: 134 QAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLLQSNPVLEAFGNAKTLRND 193 Query: 292 NSSRFGKFIQVSYLESGIVRGAVVEKYLLEKSRLVSQEKDERNYHVFYYLLLGVSEEERQ 351 NSSRFGK++ V + G G + YLLEKSR+V Q ERN+H+FY LL G EE + Sbjct: 194 NSSRFGKYMDVQFDFKGAPVGGHILSYLLEKSRVVHQNHGERNFHIFYQLLEGGEEETLR 253 Query: 352 EFQLKQ-PEDYFYLNQHNLKIEDGEDLKHDFERLKQAMEMVGFLPATKKQIFAVLSAILY 410 L++ P+ Y YL + + K D++ +++A+ ++ F + + ++++++L+ Sbjct: 254 RLGLERNPQSYLYLVKGQCAKVSSINDKSDWKVVRKALTVIDFTEDEVEDLLSIVASVLH 313 Query: 411 LGNVTYKKRATGREEGLEVGPPEVLDTLSQLLKVKREILVEVLTKRKTVTVNDKLILPYS 470 LGN+ + A E +V L L++LL V+ L E LT RK + ++L+ P + Sbjct: 314 LGNIHF---AANEESNAQVTTENQLKYLTRLLSVEGSTLREALTHRKIIAKGEELLSPLN 370 Query: 471 LSEAITARDSMAKSLYSALFDWIVLRINHALLNKKDVEEAV--SCLSIGVLDIFGFEDFE 528 L +A ARD++AK++YS F W+V +IN +L +K DVE S +G+LDI+GFE F+ Sbjct: 371 LEQAAYARDALAKAVYSRTFTWLVGKINRSLASK-DVESPSWRSTTVLGLLDIYGFEVFQ 429 Query: 529 RNSFEQFCINYANEQLQYYFNQHIFKLEQEEYQGEGITWHNIGYTDNVGCIHLISKKPTG 588 NSFEQFCINY NE+LQ F + K EQEEY+ EGI W + Y +N L+ +K G Sbjct: 430 HNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEPVQYFNNKIICDLVEEKFKG 489 Query: 589 LFYLLDEESNFP-HATSQTLLAKFKQQHEDNKYFLGTPVMEP---------AFIIQHFAG 638 + +LDEE P AT T L K + + + +FL + + F + H+AG Sbjct: 490 IISILDEECLRPGEATDLTFLEKLEDTVKHHPHFLTHKLADQRTRKSLGRGEFRLLHYAG 549 Query: 639 KVKYQIKDFREKNMDYM 655 +V Y + F +KN D + Sbjct: 550 EVTYSVTGFLDKNNDLL 566 Score = 106 bits (265), Expect = 2e-22 Identities = 74/241 (30%), Positives = 138/241 (57%), Gaps = 16/241 (6%) Query: 784 KQKQIIPKNLLDSK-SLKLIISMTLHDRTTKSLLHLHKKKKPPSISAQFQTSLNKLLEAL 842 K ++ +NL ++ S K I DR+ L KK+P +++ QF+ SL +L+E L Sbjct: 561 KNNDLLFRNLKETMCSSKNPIMSQCFDRS-----ELSDKKRPETVATQFKMSLLQLVEIL 615 Query: 843 GKAEPFFIRCIRSNAEKKELCFDDELVLQQLRYTGMLETVRIRRSGYSAKYTFQDFTEQF 902 EP ++RCI+ N K+ FD+ L+ Q++Y G+LE +R+RR+G++ + ++ F +++ Sbjct: 616 QSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLGLLENLRVRRAGFAYRRKYEAFLQRY 675 Query: 903 QVLLPKD----AQPCREVISTLLEKMKIDKRNYQIGKTKVFLKETERQ-ALQETLHREVV 957 + L P+ A ++ ++ L+ + Y++G+TK+F++ + A ++ L EV Sbjct: 676 KSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKMGRTKIFIRFPKTLFATEDAL--EVR 733 Query: 958 RKILL--LQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRR-ALERTQAAVYLQASWRG 1014 R+ L +Q+ +R R+ FL++KR+A+ IQ+ WR RR A +R AA ++ RG Sbjct: 734 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWAAQTIRRLIRG 793 Query: 1015 Y 1015 + Sbjct: 794 F 794 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.131 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,760,211 Number of Sequences: 37866 Number of extensions: 4505141 Number of successful extensions: 35343 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 285 Number of HSP's successfully gapped in prelim test: 1232 Number of HSP's that attempted gapping in prelim test: 25719 Number of HSP's gapped (non-prelim): 8852 length of query: 2157 length of database: 18,247,518 effective HSP length: 118 effective length of query: 2039 effective length of database: 13,779,330 effective search space: 28096053870 effective search space used: 28096053870 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.