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Search of human proteins with 33300663
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33300663 polycomb group ring finger 5 [Homo sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33300663 polycomb group ring finger 5 [Homo sapiens] 543 e-155
gi|31742478 ring finger protein 3 [Homo sapiens] 211 4e-55
gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens] 146 2e-35
gi|109240538 polycomb group ring finger 1 [Homo sapiens] 145 3e-35
gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens] 138 4e-33
gi|6005964 ring finger protein 110 [Homo sapiens] 137 9e-33
gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens] 90 2e-18
gi|6005747 ring finger protein 2 [Homo sapiens] 50 1e-06
gi|31542779 tripartite motif family-like 1 [Homo sapiens] 48 7e-06
gi|21071052 helicase-like transcription factor [Homo sapiens] 47 2e-05
gi|21071054 helicase-like transcription factor [Homo sapiens] 47 2e-05
gi|51479192 ring finger protein 1 [Homo sapiens] 47 2e-05
gi|148528975 LON peptidase N-terminal domain and ring finger 2 [... 45 6e-05
gi|157743261 tripartite motif-containing 75 [Homo sapiens] 45 8e-05
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens] 44 2e-04
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens] 44 2e-04
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens] 44 2e-04
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens] 44 2e-04
gi|88953346 PREDICTED: Tripartite motif-containing protein 43-li... 44 2e-04
gi|20270353 tripartite motif-containing 43 [Homo sapiens] 44 2e-04
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens] 43 2e-04
gi|37588861 ring finger protein 41 isoform 1 [Homo sapiens] 43 2e-04
gi|5032071 ring finger protein 41 isoform 1 [Homo sapiens] 43 2e-04
gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo s... 43 3e-04
gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo... 43 3e-04
gi|87080813 LON peptidase N-terminal domain and ring finger 1 [H... 43 3e-04
gi|87241872 ring finger protein 151 [Homo sapiens] 43 3e-04
gi|209862805 SPRY domain containing 5 [Homo sapiens] 42 4e-04
gi|30425428 deltex homolog 3 [Homo sapiens] 42 4e-04
gi|223468632 tripartite motif-containing 53 [Homo sapiens] 42 5e-04
>gi|33300663 polycomb group ring finger 5 [Homo sapiens]
Length = 256
Score = 543 bits (1399), Expect = e-155
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV 60
MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV
Sbjct: 1 MATQRKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQV 60
Query: 61 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVD 120
HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVD
Sbjct: 61 HETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVD 120
Query: 121 EEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFL 180
EEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFL
Sbjct: 121 EEGDENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFL 180
Query: 181 SLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLY 240
SLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLY
Sbjct: 181 SLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLY 240
Query: 241 QSYPMVLQYRPRIDFG 256
QSYPMVLQYRPRIDFG
Sbjct: 241 QSYPMVLQYRPRIDFG 256
>gi|31742478 ring finger protein 3 [Homo sapiens]
Length = 242
Score = 211 bits (538), Expect = 4e-55
Identities = 105/267 (39%), Positives = 163/267 (61%), Gaps = 47/267 (17%)
Query: 5 RKHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETN 64
RK + D N +ITC +C GYLI TTVTECLHTFC++C+V++ E++N CP C +H+++
Sbjct: 4 RKIKLWDINAHITCRLCSGYLIDATTVTECLHTFCRSCLVKYLEENNTCPTCRIVIHQSH 63
Query: 65 PLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKK----------------NKPQENGQ 108
PL+ + D T+++I++KLVPGL+E E+ ++ EF+ K + ++ +
Sbjct: 64 PLQYIGHDRTMQDIVYKLVPGLQEAEMRKQREFYHKLGMEVPGDIKGETCSAKQHLDSHR 123
Query: 109 DDTSKADKPKVDEEGDEN-EDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRC 167
+ +KAD E +E E+D DYHRSD Q++ICL+C + ++GL +K+IRC
Sbjct: 124 NGETKADDSSNKEAAEEKPEEDNDYHRSDEQVSICLEC-------NSSKLRGLKRKWIRC 176
Query: 168 STRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNC 227
S + TV +KKF++ KL L S ELD+LCN EI+GKDHT++F+ +TRWR
Sbjct: 177 SAQATVLHLKKFIAKKLNLSSFNELDILCNEEILGKDHTLKFVVVTRWR----------- 225
Query: 228 SASQVCSQDGPLYQSYPMVLQYRPRID 254
++ P++L YRP++D
Sbjct: 226 ------------FKKAPLLLHYRPKMD 240
>gi|58761530 polycomb group ring finger 6 isoform a [Homo sapiens]
Length = 350
Score = 146 bits (368), Expect = 2e-35
Identities = 85/240 (35%), Positives = 127/240 (52%), Gaps = 21/240 (8%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
+ + PYI C ICKGYLI TT+TECLHTFCK+CIV+HF SN CP+C VH+T PL
Sbjct: 125 LSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPLYN 184
Query: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKA-DKPKVDEEGDENE 127
+RLD L++I++KLV L E+E ++ +F+K E G + A +P +G +
Sbjct: 185 IRLDRQLQDIVYKLVINLEEREKKQMHDFYK-----ERGLEVPKPAVPQPVPSSKGRSKK 239
Query: 128 DDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLP 187
+ R P++ + L G K L KKF+R S T+G ++KFL K+ L
Sbjct: 240 VLESVFRIPPELDMSLLLEFIGANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLD 299
Query: 188 SSYELDVLCNGEIMGKDHTMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVL 247
+ ++D++C DH +E + + R + + QDG L Y +V+
Sbjct: 300 PACQVDIICG------DHLLE---------QYQTLREIRRAIGDAAMQDGLLVLHYGLVV 344
>gi|109240538 polycomb group ring finger 1 [Homo sapiens]
Length = 259
Score = 145 bits (366), Expect = 3e-35
Identities = 75/213 (35%), Positives = 124/213 (58%), Gaps = 15/213 (7%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
+KD N +I C +C GY + TT+TECLHTFCK+CIV++ + S CP C ++HET PL
Sbjct: 38 IKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLN 97
Query: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSK--ADKPKVDEEG--- 123
L+LD +++I++KLVPGL++ E +R EF+ Q G D ++ ++P + G
Sbjct: 98 LKLDRVMQDIVYKLVPGLQDSEEKRIREFY-----QSRGLDRVTQPTGEEPALSNLGLPF 152
Query: 124 -DENEDDKDYHRSDPQIAICLDCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSL 182
+ Y+R D Q+ +CL+ L + +V L K++RCS R V +++ L
Sbjct: 153 SSFDHSKAHYYRYDEQLNLCLERLSSGKDKNKSV---LQNKYVRCSVRAEVRHLRRVLCH 209
Query: 183 KLKLPSSYELDVLCNGEIMGKDHTMEFIYMTRW 215
+L L + + +L + E++ TM+ I+++RW
Sbjct: 210 RLML-NPQHVQLLFDNEVLPDHMTMKQIWLSRW 241
>gi|27883842 BMI1 polycomb ring finger oncogene [Homo sapiens]
Length = 326
Score = 138 bits (348), Expect = 4e-33
Identities = 73/222 (32%), Positives = 125/222 (56%), Gaps = 22/222 (9%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
+ + NP++ C +C GY I TT+ ECLH+FCKTCIV++ E S CP C QVH+T PL
Sbjct: 9 ITELNPHLMCVLCGGYFIDATTIIECLHSFCKTCIVRYLETSKYCPICDVQVHKTRPLLN 68
Query: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQENGQDDTSKADKPKVDEEGDENED 128
+R D TL++I++KLVPGL + E++R +F+ + ++ A ++ G+ ++
Sbjct: 69 IRSDKTLQDIVYKLVPGLFKNEMKRRRDFYAAH--------PSADAANGSNEDRGEVADE 120
Query: 129 DKDYHRSDPQIAICLDCLRNN----------GQSGDNVVKGLMKKFIRCSTRVTVGTIKK 178
DK D I++ ++ N +S + V K+++RC +TV ++K
Sbjct: 121 DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVND---KRYLRCPAAMTVMHLRK 177
Query: 179 FLSLKLKLPSSYELDVLCNGEIMGKDHT-MEFIYMTRWRLRG 219
FL K+ +P+++++DV+ E + +T M+ Y+ WR G
Sbjct: 178 FLRSKMDIPNTFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
>gi|6005964 ring finger protein 110 [Homo sapiens]
Length = 344
Score = 137 bits (345), Expect = 9e-33
Identities = 75/223 (33%), Positives = 123/223 (55%), Gaps = 22/223 (9%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
+ + NP++ C +C GY I TT+ ECLH+FCKTCIV++ E + CP C QVH+T PL
Sbjct: 9 ITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLS 68
Query: 69 LRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQE--NGQDDTSKADKPKVDEEGDEN 126
+R D TL++I++KLVPGL + E++R +F+ E NG + ++ G+
Sbjct: 69 IRSDKTLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSN----------EDRGEVL 118
Query: 127 EDDKDYHRSDPQIAICL---------DCLRNNGQSGDNVVKGLMKKFIRCSTRVTVGTIK 177
E +K D +++ + D + ++GD + +F+RC +TV +
Sbjct: 119 EQEKGALSDDEIVSLSIEFYEGARDRDEKKGPLENGDGDKEKTGVRFLRCPAAMTVMHLA 178
Query: 178 KFLSLKLKLPSSYELDVLCNGEIMGKDHT-MEFIYMTRWRLRG 219
KFL K+ +PS Y+++VL E + + +T M+ Y+ WR G
Sbjct: 179 KFLRNKMDVPSKYKVEVLYEDEPLKEYYTLMDIAYIYPWRRNG 221
>gi|37655165 polycomb group ring finger 6 isoform b [Homo sapiens]
Length = 275
Score = 89.7 bits (221), Expect = 2e-18
Identities = 37/58 (63%), Positives = 44/58 (75%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPL 66
+ + PYI C ICKGYLI TT+TECLHTFCK+CIV+HF SN CP+C VH+T PL
Sbjct: 125 LSELTPYILCSICKGYLIDATTITECLHTFCKSCIVRHFYYSNRCPKCNIVVHQTQPL 182
Score = 42.0 bits (97), Expect = 5e-04
Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 15/99 (15%)
Query: 149 NGQSGDNVVKGLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTME 208
+ G K L KKF+R S T+G ++KFL K+ L + ++D++C DH +E
Sbjct: 186 SANEGTGHFKPLEKKFVRVSGEATIGHVEKFLRRKMGLDPACQVDIICG------DHLLE 239
Query: 209 FIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVL 247
+ + R + + QDG L Y +V+
Sbjct: 240 ---------QYQTLREIRRAIGDAAMQDGLLVLHYGLVV 269
>gi|6005747 ring finger protein 2 [Homo sapiens]
Length = 336
Score = 50.4 bits (119), Expect = 1e-06
Identities = 64/286 (22%), Positives = 96/286 (33%), Gaps = 53/286 (18%)
Query: 16 ITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN-DCPRCGN---------------- 58
+ C IC L T ECLH FC CI+ N +CP C
Sbjct: 49 LMCPICLDMLKNTMTTKECLHRFCADCIITALRSGNKECPTCRKKLVSKRSLRPDPNFDA 108
Query: 59 ------------QVHETNPLEMLRLDNTLEEIIFKLVPGLREQELERESEFWKKNKPQEN 106
+ H+ L + N + + + GL+ Q + R K+ +
Sbjct: 109 LISKIYPSRDEYEAHQERVLARINKHNNQQALSHSIEEGLKIQAMNRLQRGKKQQIENGS 168
Query: 107 GQDDT------SKADKPKVDEEGDENE-----DDKDYHRSDPQIAICLDCLRNNGQSGDN 155
G +D S A E G N+ DD + A+ +D + + +
Sbjct: 169 GAEDNGDSSHCSNASTHSNQEAGPSNKRTKTSDDSGLELDNNNAAMAIDPVMDGASEIEL 228
Query: 156 VVK---GLMKK-------FIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDH 205
V + LM+K +I+ S TV + K+L+++L L EL M D
Sbjct: 229 VFRPHPTLMEKDDSAQTRYIKTSGNATVDHLSKYLAVRLALE---ELRSKGESNQMNLDT 285
Query: 206 TMEFIYMTRWRLRGENFRCLNCSASQVCSQDGPLYQSYPMVLQYRP 251
E Y F LN S S + + PM L Y P
Sbjct: 286 ASEKQYTIYIATASGQFTVLNGSFSLELVSEKYWKVNKPMELYYAP 331
>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
Length = 468
Score = 48.1 bits (113), Expect = 7e-06
Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 9/92 (9%)
Query: 8 LVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN---DCPRCGNQVHETN 64
L+++ +TC+IC Y P T TEC H+FC C+++ +E+ N CP C + +
Sbjct: 6 LMENLREELTCFICLDYFSSPVT-TECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPH 64
Query: 65 PLEMLRLDNTLEEIIFKLVPGLREQELERESE 96
RL + + LR Q L+ E E
Sbjct: 65 FQSNERLGR-----LASIARQLRSQVLQSEDE 91
>gi|21071052 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 47.0 bits (110), Expect = 2e-05
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCI---VQHFEDSNDCPRCGNQVHETNPLE 67
C IC L P +T C H FCK CI +Q+ + CP C N +HE N LE
Sbjct: 760 CAICLDSLTVPV-ITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811
>gi|21071054 helicase-like transcription factor [Homo sapiens]
Length = 1009
Score = 47.0 bits (110), Expect = 2e-05
Identities = 23/53 (43%), Positives = 28/53 (52%), Gaps = 4/53 (7%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCI---VQHFEDSNDCPRCGNQVHETNPLE 67
C IC L P +T C H FCK CI +Q+ + CP C N +HE N LE
Sbjct: 760 CAICLDSLTVPV-ITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLE 811
>gi|51479192 ring finger protein 1 [Homo sapiens]
Length = 406
Score = 47.0 bits (110), Expect = 2e-05
Identities = 26/80 (32%), Positives = 35/80 (43%), Gaps = 4/80 (5%)
Query: 16 ITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN-DCPRCGNQVHETNPLEMLRLDNT 74
+ C IC L T ECLH FC CIV N +CP C ++ LR D
Sbjct: 46 LMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSK---RSLRPDPN 102
Query: 75 LEEIIFKLVPGLREQELERE 94
+ +I K+ P E E ++
Sbjct: 103 FDALISKIYPSREEYEAHQD 122
>gi|148528975 LON peptidase N-terminal domain and ring finger 2
[Homo sapiens]
Length = 754
Score = 45.1 bits (105), Expect = 6e-05
Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEE 77
C +C L +P T T C HTFC C+ + + + CP C +++ E + EE
Sbjct: 449 CALCMRLLFEPVT-TPCGHTFCLKCLERCLDHAPHCPLCKDKLSELLASRNFNITVLAEE 507
Query: 78 IIFKLVP 84
+IF+ +P
Sbjct: 508 LIFRYLP 514
>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
Length = 468
Score = 44.7 bits (104), Expect = 8e-05
Identities = 27/80 (33%), Positives = 41/80 (51%), Gaps = 6/80 (7%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSND---CPRCGNQVHETNPLEMLRLDNT 74
C IC YL P T+ EC H FC++CI Q + D + CP C +Q E + +L
Sbjct: 16 CSICLDYLSDPVTI-ECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEGHFRSNTQLGRM 74
Query: 75 LEEIIFKLVPGLREQELERE 94
+E I KL+ + + ++E
Sbjct: 75 IE--IAKLLQSTKSNKRKQE 92
>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
Length = 1884
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 6 KHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDS---NDCPRCGNQVHE 62
++++ + C IC LIK T+C H FCK C+++ + CP C N + +
Sbjct: 12 QNVINAMQKILECPICLE-LIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITK 70
Query: 63 TNPLEMLRLDNTLEEII-----FKLVPGLREQELERESEFWKK-NKPQENGQDDTS 112
+ E R +EE++ F+L GL E F KK N E+ +D+ S
Sbjct: 71 RSLQESTRFSQLVEELLKIICAFQLDTGL---EYANSYNFAKKENNSPEHLKDEVS 123
>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
Length = 699
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 6 KHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDS---NDCPRCGNQVHE 62
++++ + C IC LIK T+C H FCK C+++ + CP C N + +
Sbjct: 12 QNVINAMQKILECPICLE-LIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITK 70
Query: 63 TNPLEMLRLDNTLEEII-----FKLVPGLREQELERESEFWKK-NKPQENGQDDTS 112
+ E R +EE++ F+L GL E F KK N E+ +D+ S
Sbjct: 71 RSLQESTRFSQLVEELLKIICAFQLDTGL---EYANSYNFAKKENNSPEHLKDEVS 123
>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
Length = 759
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 6 KHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDS---NDCPRCGNQVHE 62
++++ + C IC LIK T+C H FCK C+++ + CP C N + +
Sbjct: 12 QNVINAMQKILECPICLE-LIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITK 70
Query: 63 TNPLEMLRLDNTLEEII-----FKLVPGLREQELERESEFWKK-NKPQENGQDDTS 112
+ E R +EE++ F+L GL E F KK N E+ +D+ S
Sbjct: 71 RSLQESTRFSQLVEELLKIICAFQLDTGL---EYANSYNFAKKENNSPEHLKDEVS 123
>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
Length = 1863
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 6 KHLVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDS---NDCPRCGNQVHE 62
++++ + C IC LIK T+C H FCK C+++ + CP C N + +
Sbjct: 12 QNVINAMQKILECPICLE-LIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITK 70
Query: 63 TNPLEMLRLDNTLEEII-----FKLVPGLREQELERESEFWKK-NKPQENGQDDTS 112
+ E R +EE++ F+L GL E F KK N E+ +D+ S
Sbjct: 71 RSLQESTRFSQLVEELLKIICAFQLDTGL---EYANSYNFAKKENNSPEHLKDEVS 123
>gi|88953346 PREDICTED: Tripartite motif-containing protein
43-like protein 1 [Homo sapiens]
Length = 446
Score = 43.5 bits (101), Expect = 2e-04
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Query: 12 FNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN---DCPRC 56
F +TC IC YL+ P T+ C H+FC+ C+ +E++ +CP C
Sbjct: 9 FQKELTCVICLNYLVDPVTIC-CGHSFCRPCLCLSWEEAQSPANCPAC 55
>gi|20270353 tripartite motif-containing 43 [Homo sapiens]
Length = 446
Score = 43.5 bits (101), Expect = 2e-04
Identities = 18/48 (37%), Positives = 28/48 (58%), Gaps = 4/48 (8%)
Query: 12 FNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSN---DCPRC 56
F +TC IC YL+ P T+ C H+FC+ C+ +E++ +CP C
Sbjct: 9 FQKELTCVICLNYLVDPVTIC-CGHSFCRPCLCLSWEEAQSPANCPAC 55
>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
Length = 485
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/95 (25%), Positives = 45/95 (47%), Gaps = 7/95 (7%)
Query: 1 MATQRKHLVKDFNPYIT----CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRC 56
M Q++ ++ N + C IC Y I+ T+ C H+FC CI + + +CP C
Sbjct: 382 MQAQKEEVLSHMNDVLENELQCIICSEYFIEAVTLN-CAHSFCSYCINEWMKRKIECPIC 440
Query: 57 GNQVHETNPLEMLRLDNTLEEIIFKLVPGLREQEL 91
+ + L LDN + +++ L ++E+ +
Sbjct: 441 RKDI--KSKTYSLVLDNCINKMVNNLSSEVKERRI 473
>gi|37588861 ring finger protein 41 isoform 1 [Homo sapiens]
Length = 317
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/44 (38%), Positives = 20/44 (45%)
Query: 11 DFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCP 54
D + + C IC G L +P C H FC CI Q F CP
Sbjct: 11 DVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCP 54
>gi|5032071 ring finger protein 41 isoform 1 [Homo sapiens]
Length = 317
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/44 (38%), Positives = 20/44 (45%)
Query: 11 DFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCP 54
D + + C IC G L +P C H FC CI Q F CP
Sbjct: 11 DVDEDLICPICSGVLEEPVQAPHCEHAFCNACITQWFSQQQTCP 54
>gi|21359963 ring finger and WD repeat domain 2 isoform a [Homo
sapiens]
Length = 731
Score = 42.7 bits (99), Expect = 3e-04
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLE--------ML 69
C IC +I+ +T+C H+FC CI Q ED+N CP+C V + L +L
Sbjct: 136 CPICFD-MIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELIL 194
Query: 70 RLDNTLEEIIFKL 82
+ EE FKL
Sbjct: 195 KQKQRFEEKRFKL 207
>gi|50233824 ring finger and WD repeat domain 2 isoform d24 [Homo
sapiens]
Length = 707
Score = 42.7 bits (99), Expect = 3e-04
Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 9/73 (12%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLE--------ML 69
C IC +I+ +T+C H+FC CI Q ED+N CP+C V + L +L
Sbjct: 136 CPICFD-MIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNELIL 194
Query: 70 RLDNTLEEIIFKL 82
+ EE FKL
Sbjct: 195 KQKQRFEEKRFKL 207
>gi|87080813 LON peptidase N-terminal domain and ring finger 1 [Homo
sapiens]
Length = 773
Score = 42.7 bits (99), Expect = 3e-04
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 5/76 (6%)
Query: 9 VKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEM 68
V DF C +C +P T T C H+FCK C+ + + + CP C + E
Sbjct: 474 VSDFE----CSLCMRLFFEPVT-TPCGHSFCKNCLERCLDHAPYCPLCKESLKEYLADRR 528
Query: 69 LRLDNTLEEIIFKLVP 84
+ LEE+I K +P
Sbjct: 529 YCVTQLLEELIVKYLP 544
Score = 31.2 bits (69), Expect = 0.92
Identities = 11/28 (39%), Positives = 19/28 (67%), Gaps = 1/28 (3%)
Query: 16 ITCYICKGYLIKPTTVTECLHTFCKTCI 43
+ C C+G+L +P TV C H++C+ C+
Sbjct: 121 LRCLGCRGFLSEPVTV-PCGHSYCRRCL 147
>gi|87241872 ring finger protein 151 [Homo sapiens]
Length = 245
Score = 42.7 bits (99), Expect = 3e-04
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 1/64 (1%)
Query: 18 CYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLEMLRLDNTLEE 77
C +C G L +P + C H FCK CI++ CP C +V + M +L T+
Sbjct: 20 CSVCHGVLKRPARLP-CSHIFCKKCILRWLARQKTCPCCRKEVKRKKVVHMNKLRKTIGR 78
Query: 78 IIFK 81
+ K
Sbjct: 79 LEVK 82
>gi|209862805 SPRY domain containing 5 [Homo sapiens]
Length = 452
Score = 42.4 bits (98), Expect = 4e-04
Identities = 20/73 (27%), Positives = 40/73 (54%), Gaps = 2/73 (2%)
Query: 8 LVKDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCGNQVHETNPLE 67
+++ F +TC IC Y + P T+ +C H+FC+ C+ +++D+ +C ++ +T
Sbjct: 5 ILQVFQRALTCPICMNYFLDPVTI-DCGHSFCRPCLYLNWQDTAVLAQC-SECKKTTRQR 62
Query: 68 MLRLDNTLEEIIF 80
L D L+ + F
Sbjct: 63 NLNTDICLKNMAF 75
>gi|30425428 deltex homolog 3 [Homo sapiens]
Length = 347
Score = 42.4 bits (98), Expect = 4e-04
Identities = 16/41 (39%), Positives = 23/41 (56%)
Query: 17 TCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRCG 57
TC IC G + T+ +C H+FC+ CI + + CP CG
Sbjct: 163 TCPICLGEIQNAKTLEKCRHSFCEGCITRALQVKKACPMCG 203
>gi|223468632 tripartite motif-containing 53 [Homo sapiens]
Length = 285
Score = 42.0 bits (97), Expect = 5e-04
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 10 KDFNPYITCYICKGYLIKPTTVTECLHTFCKTCIVQHFEDSNDCPRC 56
+DF ITC IC Y I P T+ +C H+FC+ C +++D +C
Sbjct: 7 QDFQMEITCPICMNYFIDPVTI-DCGHSFCRPCFYFNWQDIPILTQC 52
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.430
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,197,960
Number of Sequences: 37866
Number of extensions: 538845
Number of successful extensions: 3800
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 206
Number of HSP's that attempted gapping in prelim test: 3130
Number of HSP's gapped (non-prelim): 725
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.