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Search of human proteins with 33286442
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
(1711 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 3457 0.0
gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens] 323 7e-88
gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens] 323 7e-88
gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens] 323 7e-88
gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens] 323 7e-88
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 138 4e-32
gi|116284392 mucin 2 precursor [Homo sapiens] 135 4e-31
gi|163965366 nascent polypeptide-associated complex alpha subuni... 130 8e-30
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 121 5e-27
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 119 3e-26
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 118 4e-26
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 117 7e-26
gi|91982772 mucin 17 [Homo sapiens] 117 1e-25
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 114 8e-25
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 111 5e-24
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 111 5e-24
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 111 5e-24
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 111 5e-24
gi|160707881 formin 2 [Homo sapiens] 108 6e-23
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens] 107 1e-22
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 106 2e-22
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 102 2e-21
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 102 2e-21
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 102 2e-21
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 102 3e-21
gi|47132519 Ras association and pleckstrin homology domains 1 is... 102 3e-21
gi|110832843 TBP-associated factor 4 [Homo sapiens] 100 2e-20
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 98 8e-20
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 97 2e-19
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 96 2e-19
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 3457 bits (8964), Expect = 0.0
Identities = 1711/1711 (100%), Positives = 1711/1711 (100%)
Query: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV 60
MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV
Sbjct: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKV 60
Query: 61 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGD 120
ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGD
Sbjct: 61 ELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGD 120
Query: 121 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG 180
GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG
Sbjct: 121 GLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLG 180
Query: 181 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ 240
TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ
Sbjct: 181 TGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ 240
Query: 241 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP 300
VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP
Sbjct: 241 VATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP 300
Query: 301 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP 360
APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP
Sbjct: 301 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP 360
Query: 361 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV 420
TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV
Sbjct: 361 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV 420
Query: 421 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV
Sbjct: 421 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
Query: 481 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540
LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA
Sbjct: 481 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540
Query: 541 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP 600
PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP
Sbjct: 541 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP 600
Query: 601 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST 660
LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST
Sbjct: 601 LKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST 660
Query: 661 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV 720
VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV
Sbjct: 661 VLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGV 720
Query: 721 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS 780
ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS
Sbjct: 721 ANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPS 780
Query: 781 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS 840
TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS
Sbjct: 781 TVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQAS 840
Query: 841 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD 900
LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD
Sbjct: 841 LLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQD 900
Query: 901 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD 960
PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD
Sbjct: 901 PVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSD 960
Query: 961 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE 1020
STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE
Sbjct: 961 STPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKE 1020
Query: 1021 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA 1080
LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA
Sbjct: 1021 LILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQA 1080
Query: 1081 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV 1140
EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV
Sbjct: 1081 EVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVV 1140
Query: 1141 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH 1200
RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH
Sbjct: 1141 RSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKHRKPTKPESQSPGKRADSH 1200
Query: 1201 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP 1260
EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP
Sbjct: 1201 EEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTP 1260
Query: 1261 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE 1320
TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE
Sbjct: 1261 TPAKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEE 1320
Query: 1321 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN 1380
EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN
Sbjct: 1321 EEEEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRRKGRADLKARKQKTSSSQSLEHRLRN 1380
Query: 1381 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLY 1440
RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLY
Sbjct: 1381 RNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKPSGKRKCKTKHMATVSEEAKDVVLY 1440
Query: 1441 CLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVND 1500
CLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVND
Sbjct: 1441 CLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVND 1500
Query: 1501 NLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFY 1560
NLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFY
Sbjct: 1501 NLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFY 1560
Query: 1561 SSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPC 1620
SSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPC
Sbjct: 1561 SSSVLEEKDGFACDLLHNPPGSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPC 1620
Query: 1621 NWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSP 1680
NWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSP
Sbjct: 1621 NWFLFSDVLKRLKLSSRIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSP 1680
Query: 1681 PGSSETVELVRYEPDLLRLLGSEVEFQSCNS 1711
PGSSETVELVRYEPDLLRLLGSEVEFQSCNS
Sbjct: 1681 PGSSETVELVRYEPDLLRLLGSEVEFQSCNS 1711
>gi|183396783 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 323 bits (829), Expect = 7e-88
Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)
Query: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234
G + + + + T+PE+ G + G +AK + R + L Q + S
Sbjct: 1196 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1254
Query: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290
M + S G ++ P+ + PAK++K+++ Q+ + +D
Sbjct: 1255 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1306
Query: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348
+AA + + E+ + L K K Q+SR+ TGEY E
Sbjct: 1307 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1352
Query: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407
D G+ ++ RK+ SS + Q + S + LP +
Sbjct: 1353 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1407
Query: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460
++ P R+ A T+ + A ++VVLYCL+ DVNHRDNAGY AL
Sbjct: 1408 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1467
Query: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520
HEAC+RGW +I+ LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1468 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1527
Query: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580
SG+T MK+ S+ M++FL+D+L+DLQGR + D +WDFY SSV E D D+L NPP
Sbjct: 1528 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1587
Query: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640
G DQ+ DD D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1588 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1647
Query: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700
FP+ EI T+ +AEFYRQV++S L + ++ + P S E ++LV + ++ LL
Sbjct: 1648 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1703
Query: 1701 GSEVEF 1706
GS VE+
Sbjct: 1704 GSSVEW 1709
Score = 52.0 bits (123), Expect = 5e-06
Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)
Query: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45
M+S PLY VH+W +S+R+RMCG +E+R+ ++D +++ D
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 46 FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90
+ + S + L + G GS +G + S LG SE
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
Query: 91 -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133
KP+ P+ A + GF +P GL PASD
Sbjct: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
Query: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193
N S+ L +PA LDS N + L +P +
Sbjct: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
Query: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
+ PL +P+C +P P V +P S P++++T P+ SP +
Sbjct: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
Query: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311
P+ A +S NP+ A + P + V P L +P S
Sbjct: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
Query: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370
P + P P+A T ++ P+ S P S+G P P
Sbjct: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
Query: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427
P P A A +P + T T P+ S + V A++A
Sbjct: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
Query: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
M+K+ TVL S+ G LS + +P TL+ P +
Sbjct: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
Query: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544
C + S + + P ++ V P ++ K +SL+ L P +++ P G
Sbjct: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
Query: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
+ + S +SA P PAP+ ++ +GT + S +++
Sbjct: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
Query: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646
P + + + PP ++ SSK + P P N+ PP +
Sbjct: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
Score = 47.8 bits (112), Expect = 9e-05
Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)
Query: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
M ATPA P +P S ++ + P Q + + P V T + +Y+PPP
Sbjct: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508
P ++L + + +S+ P +P + D+ LP + SP + +YP+ +
Sbjct: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
Query: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
+P +K V +L + P SP TQPA D + A++
Sbjct: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
Query: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
+P L P + + PA K P E V K+ Q ++ +SP
Sbjct: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
Query: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
P + ++ PLDLSSK + K VL S +LS S
Sbjct: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
Query: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705
+ T + GN + + + S +V+ P NG S +KN
Sbjct: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
Query: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
+ A+I+ + G+ P AS N N + R + P I G
Sbjct: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
Query: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815
+P T A S GA+ P + + P E P P + P
Sbjct: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
+ G S L Y LL G G L P G P
Sbjct: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
Query: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900
+GLP G+P FV QD
Sbjct: 704 ------YGLPTGRP----EFVTYQD 718
>gi|183396787 BCL-6 interacting corepressor isoform c [Homo sapiens]
Length = 1755
Score = 323 bits (829), Expect = 7e-88
Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)
Query: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234
G + + + + T+PE+ G + G +AK + R + L Q + S
Sbjct: 1230 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1288
Query: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290
M + S G ++ P+ + PAK++K+++ Q+ + +D
Sbjct: 1289 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1340
Query: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348
+AA + + E+ + L K K Q+SR+ TGEY E
Sbjct: 1341 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1386
Query: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407
D G+ ++ RK+ SS + Q + S + LP +
Sbjct: 1387 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1441
Query: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460
++ P R+ A T+ + A ++VVLYCL+ DVNHRDNAGY AL
Sbjct: 1442 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1501
Query: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520
HEAC+RGW +I+ LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1502 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1561
Query: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580
SG+T MK+ S+ M++FL+D+L+DLQGR + D +WDFY SSV E D D+L NPP
Sbjct: 1562 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1621
Query: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640
G DQ+ DD D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1622 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1681
Query: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700
FP+ EI T+ +AEFYRQV++S L + ++ + P S E ++LV + ++ LL
Sbjct: 1682 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1737
Query: 1701 GSEVEF 1706
GS VE+
Sbjct: 1738 GSSVEW 1743
Score = 52.0 bits (123), Expect = 5e-06
Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)
Query: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45
M+S PLY VH+W +S+R+RMCG +E+R+ ++D +++ D
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 46 FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90
+ + S + L + G GS +G + S LG SE
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
Query: 91 -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133
KP+ P+ A + GF +P GL PASD
Sbjct: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
Query: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193
N S+ L +PA LDS N + L +P +
Sbjct: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
Query: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
+ PL +P+C +P P V +P S P++++T P+ SP +
Sbjct: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
Query: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311
P+ A +S NP+ A + P + V P L +P S
Sbjct: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
Query: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370
P + P P+A T ++ P+ S P S+G P P
Sbjct: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
Query: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427
P P A A +P + T T P+ S + V A++A
Sbjct: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
Query: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
M+K+ TVL S+ G LS + +P TL+ P +
Sbjct: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
Query: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544
C + S + + P ++ V P ++ K +SL+ L P +++ P G
Sbjct: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
Query: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
+ + S +SA P PAP+ ++ +GT + S +++
Sbjct: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
Query: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646
P + + + PP ++ SSK + P P N+ PP +
Sbjct: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
Score = 47.8 bits (112), Expect = 9e-05
Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)
Query: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
M ATPA P +P S ++ + P Q + + P V T + +Y+PPP
Sbjct: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508
P ++L + + +S+ P +P + D+ LP + SP + +YP+ +
Sbjct: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
Query: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
+P +K V +L + P SP TQPA D + A++
Sbjct: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
Query: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
+P L P + + PA K P E V K+ Q ++ +SP
Sbjct: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
Query: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
P + ++ PLDLSSK + K VL S +LS S
Sbjct: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
Query: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705
+ T + GN + + + S +V+ P NG S +KN
Sbjct: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
Query: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
+ A+I+ + G+ P AS N N + R + P I G
Sbjct: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
Query: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815
+P T A S GA+ P + + P E P P + P
Sbjct: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
+ G S L Y LL G G L P G P
Sbjct: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
Query: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900
+GLP G+P FV QD
Sbjct: 704 ------YGLPTGRP----EFVTYQD 718
>gi|183396785 BCL-6 interacting corepressor isoform b [Homo sapiens]
Length = 1703
Score = 323 bits (829), Expect = 7e-88
Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)
Query: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234
G + + + + T+PE+ G + G +AK + R + L Q + S
Sbjct: 1178 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1236
Query: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290
M + S G ++ P+ + PAK++K+++ Q+ + +D
Sbjct: 1237 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1288
Query: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348
+AA + + E+ + L K K Q+SR+ TGEY E
Sbjct: 1289 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1334
Query: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407
D G+ ++ RK+ SS + Q + S + LP +
Sbjct: 1335 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1389
Query: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460
++ P R+ A T+ + A ++VVLYCL+ DVNHRDNAGY AL
Sbjct: 1390 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1449
Query: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520
HEAC+RGW +I+ LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1450 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1509
Query: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580
SG+T MK+ S+ M++FL+D+L+DLQGR + D +WDFY SSV E D D+L NPP
Sbjct: 1510 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1569
Query: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640
G DQ+ DD D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1570 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1629
Query: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700
FP+ EI T+ +AEFYRQV++S L + ++ + P S E ++LV + ++ LL
Sbjct: 1630 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1685
Query: 1701 GSEVEF 1706
GS VE+
Sbjct: 1686 GSSVEW 1691
Score = 52.0 bits (123), Expect = 5e-06
Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)
Query: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45
M+S PLY VH+W +S+R+RMCG +E+R+ ++D +++ D
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 46 FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90
+ + S + L + G GS +G + S LG SE
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
Query: 91 -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133
KP+ P+ A + GF +P GL PASD
Sbjct: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
Query: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193
N S+ L +PA LDS N + L +P +
Sbjct: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
Query: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
+ PL +P+C +P P V +P S P++++T P+ SP +
Sbjct: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
Query: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311
P+ A +S NP+ A + P + V P L +P S
Sbjct: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
Query: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370
P + P P+A T ++ P+ S P S+G P P
Sbjct: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
Query: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427
P P A A +P + T T P+ S + V A++A
Sbjct: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
Query: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
M+K+ TVL S+ G LS + +P TL+ P +
Sbjct: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
Query: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544
C + S + + P ++ V P ++ K +SL+ L P +++ P G
Sbjct: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
Query: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
+ + S +SA P PAP+ ++ +GT + S +++
Sbjct: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
Query: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646
P + + + PP ++ SSK + P P N+ PP +
Sbjct: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
Score = 47.8 bits (112), Expect = 9e-05
Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)
Query: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
M ATPA P +P S ++ + P Q + + P V T + +Y+PPP
Sbjct: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508
P ++L + + +S+ P +P + D+ LP + SP + +YP+ +
Sbjct: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
Query: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
+P +K V +L + P SP TQPA D + A++
Sbjct: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
Query: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
+P L P + + PA K P E V K+ Q ++ +SP
Sbjct: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
Query: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
P + ++ PLDLSSK + K VL S +LS S
Sbjct: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
Query: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705
+ T + GN + + + S +V+ P NG S +KN
Sbjct: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
Query: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
+ A+I+ + G+ P AS N N + R + P I G
Sbjct: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
Query: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815
+P T A S GA+ P + + P E P P + P
Sbjct: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
+ G S L Y LL G G L P G P
Sbjct: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
Query: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900
+GLP G+P FV QD
Sbjct: 704 ------YGLPTGRP----EFVTYQD 718
>gi|21071037 BCL-6 interacting corepressor isoform a [Homo sapiens]
Length = 1721
Score = 323 bits (829), Expect = 7e-88
Identities = 209/546 (38%), Positives = 298/546 (54%), Gaps = 46/546 (8%)
Query: 1175 GVRGKHKHRKPTKPESQSPGKRADSHEEGSLEKKAKSSFRDFIPVVLSTRTRSQSGSICS 1234
G + + + + T+PE+ G + G +AK + R + L Q + S
Sbjct: 1196 GRQSRKEVTQATQPEAIPQGTNITEEKPGRKRAEAKGN-RSWSEESLKPSDNEQGLPVFS 1254
Query: 1235 SFAGM----ADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKSLLSQ 1290
M + S G ++ P+ + PAK++K+++ Q+ + +D
Sbjct: 1255 GSPPMKSLSSTSAGGKKQAQPSCAP--ASRPPAKQQKIKENQKTDVLCADEEED------ 1306
Query: 1291 GRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEGLLKRKKRRRQKSRKYQ--TGEYLTE 1348
+AA + + E+ + L K K Q+SR+ TGEY E
Sbjct: 1307 --------------CQAASLLQKYTDNSEKPSGKRLCKTKHLIPQESRRGLPLTGEYYVE 1352
Query: 1349 QEDEQRRKGRADLKA-RKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEP 1407
D G+ ++ RK+ SS + Q + S + LP +
Sbjct: 1353 NAD-----GKVTVRRFRKRPEPSSDYDLSPAKQEPKPFDRLQQLLPASQSTQLPCSSSPQ 1407
Query: 1408 ACLENSEKPSGKRKCKTKHMA--TVSEEA-----KDVVLYCLQKDSEDVNHRDNAGYTAL 1460
++ P R+ A T+ + A ++VVLYCL+ DVNHRDNAGY AL
Sbjct: 1408 ETTQSRPMPPEARRLIVNKNAGETLLQRAARLGYEEVVLYCLENKICDVNHRDNAGYCAL 1467
Query: 1461 HEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATY 1520
HEAC+RGW +I+ LLE+GA+VNCSAQDGTRP+HDAV ND+LE + LLLSYGADPTLATY
Sbjct: 1468 HEACARGWLNIVRHLLEYGADVNCSAQDGTRPLHDAVENDHLEIVRLLLSYGADPTLATY 1527
Query: 1521 SGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWDFYSSSVLEEKDGFACDLLHNPP 1580
SG+T MK+ S+ M++FL+D+L+DLQGR + D +WDFY SSV E D D+L NPP
Sbjct: 1528 SGRTIMKMTHSELMEKFLTDYLNDLQGRNDDDASGTWDFYGSSVCEPDDESGYDVLANPP 1587
Query: 1581 GSSDQEGDDPMEEDDFMFELSDKPLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSSRIFQ 1640
G DQ+ DD D F FE S+ PLLPCYN+QVSV++GP NW L SDVLK+LK+SSRIF+
Sbjct: 1588 GPEDQDDDDDAYSDVFEFEFSETPLLPCYNIQVSVAQGPRNWLLLSDVLKKLKMSSRIFR 1647
Query: 1641 ARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEPDLLRLL 1700
FP+ EI T+ +AEFYRQV++S L + ++ + P S E ++LV + ++ LL
Sbjct: 1648 CNFPNVEIVTIAEAEFYRQVSASLLFSCSKDLEAFN----PESKELLDLVEFTNEIQTLL 1703
Query: 1701 GSEVEF 1706
GS VE+
Sbjct: 1704 GSSVEW 1709
Score = 52.0 bits (123), Expect = 5e-06
Identities = 149/707 (21%), Positives = 244/707 (34%), Gaps = 130/707 (18%)
Query: 1 MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTG---------------DCQH 45
M+S PLY VH+W +S+R+RMCG +E+R+ ++D +++ D
Sbjct: 1 MLSATPLYGNVHSWMNSERVRMCGASEDRKILVNDGDASKARLELREENPLNHNVVDAST 60
Query: 46 FGSQEFCVSSSFSKVEL--------------TAVGSGSNARGADPDGSATEKLGHKSED- 90
+ + S + L + G GS +G + S LG SE
Sbjct: 61 AHRIDGLAALSMDRTGLIREGLRVPGNIVYSSLCGLGSE-KGREAATSTLGGLGFSSERN 119
Query: 91 -----KPDDPQPKMDYAGNVAEAEGFLVPLSSPGD------------GLKLPASDSAEAS 133
KP+ P+ A + GF +P GL PASD
Sbjct: 120 PEMQFKPNTPETVEASAVSGKPPNGFSAIYKTPPGIQKSAVATAEALGLDRPASDKQSPL 179
Query: 134 NSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVT 193
N S+ L +PA LDS N + L +P +
Sbjct: 180 NING-ASYLRLPWVNPYMEGATPAIYPFLDS------PNKYSLNMYKALLPQQS-----Y 227
Query: 194 TNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
+ PL +P+C +P P V +P S P++++T P+ SP +
Sbjct: 228 SLAQPLYSPVCTNGERFLYLP--------PPHYVGPHIPSSLASPMRLST--PSASPAIP 277
Query: 254 PVPALAPAPPSVPTLISDSNPLSVSA--SVLVPVPASAPPSGPVPLSAPAPAPLSVPVSA 311
P+ A +S NP+ A + P + V P L +P S
Sbjct: 278 PLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNSKQPRVPSAKAVTSGLPGDTALLLPPSP 337
Query: 312 PPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTP 370
P + P P+A T ++ P+ S P S+G P P
Sbjct: 338 RPSPRVHLPTQPAADTYSEFHKHYARISTSPSVALSKPYMTVSSEFPAARLSNGKYPKAP 397
Query: 371 TLIPAFAPTPVPAPTPAPIFT---PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA 427
P P A A +P + T T P+ S + V A++A
Sbjct: 398 EGGEGAQPVPGHARKTAVQDRKDGSSPPLLEKQTVTKDVTDKPLDLSSKV--VDVDASKA 455
Query: 428 PAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
M+K+ TVL S+ G LS + +P TL+ P +
Sbjct: 456 DHMKKM-----APTVLVHSR-------AGSGLVLSGSEIP-----KETLSPP------GN 492
Query: 488 RCLPGVLASPELRSYPYAFSVARPLTSD---SKLVSLEVNRLPCTSPSGSTTTQPAPDGV 544
C + S + + P ++ V P ++ K +SL+ L P +++ P G
Sbjct: 493 GC--AIYRSEIISTAPSSWVVPGPSPNEENNGKSMSLKNKALDWAIPQQRSSSCPRMGGT 550
Query: 545 PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
+ + S +SA P PAP+ ++ +GT + S +++
Sbjct: 551 DAVITNVSGSVSSA---GRPASASPAPNANA----------------DGTKTSRSSVETT 591
Query: 605 PQLEREMASPPEC-SEMPLDLSSKSNRQKLPLP----NQRKTPPMPV 646
P + + + PP ++ SSK + P P N+ PP +
Sbjct: 592 PSVIQHVGQPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSI 638
Score = 47.8 bits (112), Expect = 9e-05
Identities = 126/565 (22%), Positives = 191/565 (33%), Gaps = 103/565 (18%)
Query: 397 MPAATPAAIP-TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
M ATPA P +P S ++ + P Q + + P V T + +Y+PPP
Sbjct: 196 MEGATPAIYPFLDSPNKYSLNMYKALLPQQSYSLAQPL---YSP--VCTNGERFLYLPPP 250
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPS--YLQDRCLPGVL-ASP----ELRSYPYAFSV 508
P ++L + + +S+ P +P + D+ LP + SP + +YP+ +
Sbjct: 251 HYVGPHIPSSLASPMRLSTPSASPAIPPLVHCADKSLPWKMGVSPGNPVDSHAYPHIQNS 310
Query: 509 ARPLTSDSKLV--------SLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
+P +K V +L + P SP TQPA D + A++
Sbjct: 311 KQPRVPSAKAVTSGLPGDTALLLPPSPRPSPRVHLPTQPAAD------TYSEFHKHYARI 364
Query: 561 LPTPQPLLPAPSGSSAPPHPA------KMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
+P L P + + PA K P E V K+ Q ++ +SP
Sbjct: 365 STSPSVALSKPYMTVSSEFPAARLSNGKYPKAPEGGEGAQPVPGHARKTAVQDRKDGSSP 424
Query: 615 P---------ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
P + ++ PLDLSSK + K VL S +LS S
Sbjct: 425 PLLEKQTVTKDVTDKPLDLSSKVVDVDASKADHMKKMAPTVLVHSRAGSGLVLSG--SEI 482
Query: 666 QRTTQAAGGN-----VTSCLGSTSSPFVI---FPEIVRNGDPSTWVKN------------ 705
+ T + GN + + + S +V+ P NG S +KN
Sbjct: 483 PKETLSPPGNGCAIYRSEIISTAPSSWVVPGPSPNEENNG-KSMSLKNKALDWAIPQQRS 541
Query: 706 --------STALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
+ A+I+ + G+ P AS N N + R + P I G
Sbjct: 542 SSCPRMGGTDAVITNVSGSVSSAGRPASASPAPN--ANADGTKTSRSSVETTPSVIQHVG 599
Query: 758 EPKGTGATCGKKGSQAGAE-GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG-PANIYP 815
+P T A S GA+ P + + P E P P + P
Sbjct: 600 QPPATPAKHSSSTSSKGAKASNPEPSFKANENGLPPSSIFLSPNEAFRSPPIPYPRSYLP 659
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
+ G S L Y LL G G L P G P
Sbjct: 660 YPAPEGIAVSPLSLHGKGPVYPHPVLLPNGSLFPGHLAPKPGLP---------------- 703
Query: 876 SSSEAVHGLPEGQPRPGGSFVPEQD 900
+GLP G+P FV QD
Sbjct: 704 ------YGLPTGRP----EFVTYQD 718
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 138 bits (348), Expect = 4e-32
Identities = 156/535 (29%), Positives = 206/535 (38%), Gaps = 99/535 (18%)
Query: 175 ILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLS------VP 228
+ A+ P+ + PL + P PA P P S+ + V VPLS VP
Sbjct: 1385 VSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVP 1444
Query: 229 APVPHSGLVPVQVATSVP------------APSPPLAPVPALAPAPPSV----------- 265
+P P+ + S P + +PPLAPV AP PPS+
Sbjct: 1445 TTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASA 1504
Query: 266 --------PTLISDSNP-----LSVSAS---------------VLVPVPASAPPSGPVPL 297
P+L S P L+ ++S VLVP A A P P
Sbjct: 1505 LTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPN 1564
Query: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAP-TLVLAPVPTPVLAPMPASTPPAAPAPPSVP 356
APA A L P S+ AL P +AP T +LAP P P LAP+P P AP
Sbjct: 1565 PAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS 1624
Query: 357 MPTPTPSSGPPSTP-----TLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPI 411
TP P P STP + P APTPV AP+ PAP P P +PA+ T A
Sbjct: 1625 SQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALA 1684
Query: 412 PASFSLSRVCFPAAQAPAMQKVPLSFQPGTV--LTPSQPLVYIPPPSCGQPLSVATLPTT 469
PA P+ P P LTP+ LV P+ Q LS+A P
Sbjct: 1685 PALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLV----PTPAQTLSLAPGP-P 1739
Query: 470 LGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRL--- 526
LG + TL+L P P ASP + + ++A +S S L V L
Sbjct: 1740 LGPTQTLSLAPAP--------PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLS 1791
Query: 527 ----PCTSPSGSTTTQPAPDGVPGPLAD-TSLVTASAKVLPTPQPLLPAPSGSSAPPHPA 581
P P+ + T AP P + +SLV +++ P P ++ S P
Sbjct: 1792 PAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTL 1851
Query: 582 KMPSGTEQQTEGTSVTFS---PLKSPPQLEREMASPPECSEMPLD-LSSKSNRQK 632
+ SG T+ +F P + PP PP S LD L K RQ+
Sbjct: 1852 TLRSG-PPSPPSTATSFGGPRPRRQPP--------PPPRSPFYLDSLEEKRKRQR 1897
Score = 128 bits (321), Expect = 5e-29
Identities = 172/605 (28%), Positives = 232/605 (38%), Gaps = 88/605 (14%)
Query: 172 NTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVP--- 228
NT ++ + P +G P+ PL PP+ G +V + P L P
Sbjct: 1305 NTGVVKIVVRQAPRDGLTPV-----PPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLG 1359
Query: 229 ---APVPHSGLV-PVQVATSVPAP-----SPPLAP--------VPALAPAPPSVPTLISD 271
AP+P LV P+ P+P +P AP VP+ P P S P I +
Sbjct: 1360 TARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPN 1419
Query: 272 SNPLS--VSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPL------ALIQAPVPP 323
S+PL+ VS++V VP+ +S P S P L APA APL++P+SAP AL+ + PP
Sbjct: 1420 SSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPP 1479
Query: 324 SAPTLVLAPVPTPVLAPMPASTPPAA--------PAPPSVPMP------TPTPSSGPPST 369
AP + AP P P LAP AS +A P+ S P PT S P
Sbjct: 1480 LAPVVPAAPGP-PSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLN 1538
Query: 370 PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPA 429
T+ PA +P VPA A F AP P PA S PAS + + P A A
Sbjct: 1539 STVAPACSPVLVPASALASPFPSAPNPAPAQA------SLLAPASSASQALATPLAPMAA 1592
Query: 430 MQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRC 489
Q L+ P L P L P P L+ + P + S+ L S
Sbjct: 1593 PQTAILAPSPAPPLAPLPVLA--PSPGAAPVLASSQTPVPVMAPSSTPGTSLAS------ 1644
Query: 490 LPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVP---- 545
ASP P V P ++ + L + + LP SP+ + T AP P
Sbjct: 1645 -----ASP----VPAPTPVLAPSSTQTMLPAPVPSPLP--SPASTQTLALAPALAPTLGG 1693
Query: 546 -GPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSP 604
P SL T + + P P L SS P PA+ S G + T S +P
Sbjct: 1694 SSPSQTLSLGTGNPQG-PFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAP 1752
Query: 605 PQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKT---PPMPVLTPVHTSSKALLSTV 661
P P + L +S S P Q T P+P L P + AL
Sbjct: 1753 PLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAP-- 1810
Query: 662 LSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEI-VRNGDPSTWVKNSTALISTIPGTYVGV 720
+ +Q A V S G+ P + + V +P T S + P T
Sbjct: 1811 -ASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGP--PSPPSTATSF 1867
Query: 721 ANPVP 725
P P
Sbjct: 1868 GGPRP 1872
Score = 119 bits (299), Expect = 2e-26
Identities = 141/515 (27%), Positives = 201/515 (39%), Gaps = 74/515 (14%)
Query: 176 LATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSG 235
+A + P G P+ + P P PAP S+P + A QVP P V ++G
Sbjct: 1257 VALIQAVAPTPGPTPV---SVLPSSTPSTTPAPTGLSLPLA---ANQVP---PTMVNNTG 1307
Query: 236 LVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV 295
+V + V AP L PVP LAPAP P S +VL P P P P
Sbjct: 1308 VVKIVVRQ---APRDGLTPVPPLAPAPRP---------PSSGLPAVLNPRPTLTPGRLPT 1355
Query: 296 PLSAPAPAPLSVPVSAPPLA-LIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPS 354
P A AP+ P PL L+ +P P + + AP P+ P P + P P S
Sbjct: 1356 PTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS---APGAAPLTISSPLHVPSSLPGPAS 1412
Query: 355 VPMPTP--TPSSGPPSTPTLIPAFA------PTPVPAPTPAPIFTPAPTPM------PAA 400
PMP P +P + P S+ +P + PT +PAP AP+ P P+ PA
Sbjct: 1413 SPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPAL 1472
Query: 401 TPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQP 460
+ P AP+ + P+ +P+ + L L+ SQ + G P
Sbjct: 1473 LTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ--------TPGHP 1524
Query: 461 LSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRS--------YPYAFSVARPL 512
L +A PT+ V P L S + C P ++ + L S P S+ P
Sbjct: 1525 LLLA--PTSSHV------PGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPA 1576
Query: 513 TSDSK-----LVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPL 567
+S S+ L + + +PS + P P P P A L ++ V
Sbjct: 1577 SSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSS 1636
Query: 568 LPAPSGSSAPPHPAKMP--SGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLS 625
P S +SA P PA P + + QT + SPL SP + +P + L
Sbjct: 1637 TPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP----ALAPTLG 1692
Query: 626 SKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLST 660
S Q L L P P T T + +L+ T
Sbjct: 1693 GSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT 1727
Score = 101 bits (251), Expect = 7e-21
Identities = 182/763 (23%), Positives = 265/763 (34%), Gaps = 135/763 (17%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVP-APVPHSGLVPVQVATSVPAP 248
PL+ + P P + P P S S+P +P V P P L P A +P
Sbjct: 1059 PLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSP 1118
Query: 249 SPPLAPVPALAPA--------PPSVPTLISDSNPLSVSASVLVPVPA-----------SA 289
+PP L P PP+ T S + + + +V P PA +
Sbjct: 1119 APPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQAR 1178
Query: 290 PPSGPV-------------PLSAPAPAPLSVPVSAPPLALIQAPV--------------- 321
PSG V +A PL+ + L L A V
Sbjct: 1179 LPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNV 1238
Query: 322 --------------PPSAPTLVLAPVPTPVLAP---MPASTPPAAPAPPSVPMP---TPT 361
P+ L+ A PTP P +P+STP PAP + +P
Sbjct: 1239 VHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQV 1298
Query: 362 PSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVC 421
P + +T + P TP P PAP P + PA + P L
Sbjct: 1299 PPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVL-NPRPTLTPGRLPTPT 1357
Query: 422 FPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL 481
A+AP T++ P LV+ P P + A L +SS L +P
Sbjct: 1358 LGTARAP--------MPTPTLVRPLLKLVHSPSPEVS---ASAPGAAPLTISSPLHVP-- 1404
Query: 482 PSYLQDRCLPGVLASP------ELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGST 535
LPG +SP + P + +V+ PL+S + P ++P
Sbjct: 1405 ------SSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIP 1458
Query: 536 TTQPAPDGVPGPLADTSLVTASAKVLP-TPQPLLPAPSGSSAPPHP-----AKMPSGTEQ 589
+ P GP TS+ A V+P P P APSG+S A PS +
Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSS 1518
Query: 590 QTEGTSVTFSPLKS-PPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPP--MPV 646
QT G + +P S P L +A P CS + + S+ ++ P P+ P +
Sbjct: 1519 QTPGHPLLLAPTSSHVPGLNSTVA--PACSPVLVPASALAS----PFPSAPNPAPAQASL 1572
Query: 647 LTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS 706
L P ++S+AL + + A S + P P + + + + +S
Sbjct: 1573 LAPASSASQALATPL-------APMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASS 1625
Query: 707 TALI-----STIPGTYVGVANPVPA-SLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPK 760
+ S+ PGT + A+PVPA + +L + P P P S
Sbjct: 1626 QTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685
Query: 761 GTGATC-GKKGSQAGAEGQ-------PSTVKRYTPARIAPGLPGCQTKELSLWKPTGPAN 812
T G SQ + G P+ TPA P QT L+ P GP
Sbjct: 1686 ALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTP-AQTLSLAPGPPLGPTQ 1744
Query: 813 IYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPS 855
S+ P PVG +P H +L SSA L P+
Sbjct: 1745 ---TLSLAPAPPLAPASPVGPAPAHTLTLAPAS-SSASLLAPA 1783
Score = 92.8 bits (229), Expect = 3e-18
Identities = 212/858 (24%), Positives = 291/858 (33%), Gaps = 197/858 (22%)
Query: 237 VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP-- 294
VP Q +V + P AP+ + PP P L + P V + + SA P+GP
Sbjct: 1001 VPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPL 1060
Query: 295 VPLSAPAPAPLSVPVSAP-----------PLALIQAPVPPSAPTLVLAPV-PTPV-LAPM 341
+P S P P P+ +P P PL ++ P PTL L P P PV L+P
Sbjct: 1061 IPASRP-PGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPA 1119
Query: 342 PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT 401
P + P +VP P + +T T T VPAPTPAP M A
Sbjct: 1120 PPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARL 1179
Query: 402 PAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQ-PGTVLTPS-----QPLVYIPPP 455
P+ S AS + P A A + PL+FQ G LT + Q V P P
Sbjct: 1180 PSGEVVSIGQLASLAQR----PVANAGGSK--PLTFQIQGNKLTLTGAQVRQLAVGQPRP 1233
Query: 456 ---------SCG-------QPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPEL 499
S G QP VA + + VLPS P +P
Sbjct: 1234 LQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPS-----STPSTTPAPTG 1288
Query: 500 RSYPYAFSVARP-LTSDSKLVSLEVNR------------LPCTSPSGS---TTTQPAPDG 543
S P A + P + +++ +V + V + P P S P P
Sbjct: 1289 LSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTL 1348
Query: 544 VPGPLADTSLVTASAKVLPTP---QPLL-----PAPSGSSAPPHPAKMPSGTEQQTEGTS 595
PG L +L TA A +PTP +PLL P+P S++ P A +
Sbjct: 1349 TPGRLPTPTLGTARAP-MPTPTLVRPLLKLVHSPSPEVSASAPGAAPL------------ 1395
Query: 596 VTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSK 655
SPL P L +SP +P+PN P+ +PV ++
Sbjct: 1396 TISSPLHVPSSLPGPASSP------------------MPIPNS-----SPLASPVSSTVS 1432
Query: 656 ALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVI---FPEIVRNGDPSTWVKNSTALIST 712
LS+ L S TT A S+P I P V P+ + L
Sbjct: 1433 VPLSSSLPISVPTTLPA---------PASAPLTIPISAPLTVSASGPALLTSVTPPLAPV 1483
Query: 713 IPGT------YVGVANPVPASLLLN--KDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGA 764
+P A+P ++L L P+L ++ P H P S G
Sbjct: 1484 VPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP 1543
Query: 765 TCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPT 824
C A A P P P + SL P A
Sbjct: 1544 ACSPVLVPASALASP-----------FPSAPNPAPAQASLLAPASSA------------- 1579
Query: 825 STQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSG-VPSLSSSEAVHG 883
+Q L +P + L PS P+ P V++ G P L+SS+
Sbjct: 1580 -SQALATPLAP--------MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVP 1630
Query: 884 LPEGQPRPGGSF-----VPEQDPV---TKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLAL 935
+ PG S VP PV + +T A P +P+ S QT LA
Sbjct: 1631 VMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVP-----SPLPSPASTQTLALAP 1685
Query: 936 SVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKPKNQVLATYMSHEL 995
++ P+ G S S S T +GP Q L+ + L
Sbjct: 1686 ALAPTLGG--------SSPSQTLSLGTGNPQGPF-------------PTQTLSLTPASSL 1724
Query: 996 VLATPQNLPKMPELPLLP 1013
V Q L P PL P
Sbjct: 1725 VPTPAQTLSLAPGPPLGP 1742
Score = 82.8 bits (203), Expect = 3e-15
Identities = 175/725 (24%), Positives = 263/725 (36%), Gaps = 105/725 (14%)
Query: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSA---------PTLVLAPVPTPVLAPMPASTPPA 348
+AP P P PV ++Q PVP P L PVP + P P A
Sbjct: 979 TAPDPPPRPKPVKMKVNRMLQ-PVPKQEGRTVVVVNNPRAPLGPVP---VRPPPGPELSA 1034
Query: 349 APAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIP 406
P P VP +P S P+ P LIPA P P P+ P P + P +P
Sbjct: 1035 QPTPGPVPQVLPASLMVSASPAGPPLIPASRP-------PGPVLLPPLQPNSGSLPQVLP 1087
Query: 407 TSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL--VYIPPPSCGQPLSVA 464
+P+ SR P P+ P S L + +PP P +
Sbjct: 1088 --SPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAAT 1145
Query: 465 TLPTTLGVSSTLTLPVLPSYLQDRC-----LPGVLASPELRSYPYAFSVA-RPLTS--DS 516
T TT ++T +P P+ R + L S E+ S S+A RP+ + S
Sbjct: 1146 TTSTTTATATTTAVPA-PTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGS 1204
Query: 517 KLVSLEV--NRLPCTSPSGSTTTQPAPDGVPGPLAD--TSLVTASAKVLPTPQP----LL 568
K ++ ++ N+L T G+ Q A G P PL LV+A + QP L+
Sbjct: 1205 KPLTFQIQGNKLTLT---GAQVRQLAV-GQPRPLQRNVVHLVSAGGQHHLISQPAHVALI 1260
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
A + + P + +PS T T + PL + +++P + + +
Sbjct: 1261 QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAA--------------NQVPPTMVNNT 1306
Query: 629 NRQKLPLPNQRKTP-----PMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGST 683
K+ + R+ P P+P L P + L VL + R T G T LG+
Sbjct: 1307 GVVKIVV---RQAPRDGLTPVPPLAPAPRPPSSGLPAVL--NPRPTLTPGRLPTPTLGTA 1361
Query: 684 SSPF----VIFPEIVRNGDPSTWVKNS---TALISTIPGTYVGVANPVPASLLLNKDPNL 736
+P ++ P + PS V S A ++ +V + P PAS P
Sbjct: 1362 RAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPAS-----SPMP 1416
Query: 737 GLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPG 796
N P P +S+ P + + P T+ P ++ P
Sbjct: 1417 IPNSSPLASPVSSTVSV-----PLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471
Query: 797 CQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQ 856
T S+ P P V P + P G SP AS L++G+++A L+ SQ
Sbjct: 1472 LLT---SVTPPLAPV-------VPAAPGPPSLAPSGASP--SASALTLGLATAPSLSSSQ 1519
Query: 857 GAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRP--GGSFVPEQDPVTKNKTCRIAAKP 914
P P + S VP L+S+ A P P F +P + A
Sbjct: 1520 -TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASS 1578
Query: 915 YEEQV-NPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTP-KMEGPQGAC 972
+ + P+ +PQT LA S P + + + L S TP + P
Sbjct: 1579 ASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTP 1638
Query: 973 GLKLA 977
G LA
Sbjct: 1639 GTSLA 1643
Score = 79.7 bits (195), Expect = 2e-14
Identities = 102/332 (30%), Positives = 141/332 (42%), Gaps = 66/332 (19%)
Query: 243 TSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAP 302
T+ P SP VP AP P P S P ++ A LVPVP SAP VP+SAP P
Sbjct: 2424 TTPPRCSPARERVPRPAPRPRPTPA----SAPAAIPA--LVPVPVSAP----VPISAPNP 2473
Query: 303 APLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTP 362
++ P+ ++ +P PPS + P +P P PA TPP A PP TP
Sbjct: 2474 ------ITILPVHILPSPPPPSQ----IPPCSSPACTPPPACTPPPAHTPPPAQTCLVTP 2523
Query: 363 SS----GPPSTPTLIPAFAPTPVPAPTPAPIFTPA---PTPMPAATPAAIPTSAPIPASF 415
SS GPPS P + + P+ A + A P + A+ A+ TS
Sbjct: 2524 SSPLLLGPPSVP-ISASVTNLPLGLRPEAELCAQALASPESLELASVASSETS------- 2575
Query: 416 SLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYI-------------PPPSCGQPLS 462
SLS V A++ +P+S + LTPS P + + P + G L+
Sbjct: 2576 SLSLVPPKDLLPVAVEILPVS-EKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT 2634
Query: 463 V----ATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSK- 517
V LP + S+ L LP PS D L L + R+ P +S K
Sbjct: 2635 VLPEGEELPLCVSESNGLELP--PSAASDEPLQEPLEAD--RTSEELTEAKTPTSSPEKP 2690
Query: 518 --LVSLEVNRLPCTSPSGSTTTQPAPDGVPGP 547
LV+ EV +PS S++ +P+G P P
Sbjct: 2691 QELVTAEV-----AAPSTSSSATSSPEG-PSP 2716
Score = 79.3 bits (194), Expect = 3e-14
Identities = 148/622 (23%), Positives = 219/622 (35%), Gaps = 130/622 (20%)
Query: 327 TLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTP 386
T V++ T P +P P P P PTP+S P + P L+P PVP P
Sbjct: 2412 TPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAP 2471
Query: 387 API------FTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPG 440
PI P+P P P + P P PA C P PA P
Sbjct: 2472 NPITILPVHILPSPPPPSQIPPCSSPACTPPPA-------CTP---PPAHTPPPAQ---T 2518
Query: 441 TVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR 500
++TPS PL+ + PPS SV LP L + L LASPE
Sbjct: 2519 CLVTPSSPLL-LGPPSVPISASVTNLPLGLRPEAELCAQ-------------ALASPE-- 2562
Query: 501 SYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
SLE+ + +S + S + P D L+ + ++
Sbjct: 2563 -------------------SLELASV-ASSETSSLSLVPPKD----------LLPVAVEI 2592
Query: 561 LPTPQPLLP-APSGSSAPPHPAKMPSGTEQQ----TEGTSVTFSPLKSPPQLEREMASPP 615
LP + L PS S +P+G EQ+ EGT++T P
Sbjct: 2593 LPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVL---------------P 2637
Query: 616 ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKAL--LSTVLSRSQRTTQAAG 673
E E+PL + S+SN +LP P+ P+ +S+ L T S ++ +
Sbjct: 2638 EGEELPLCV-SESNGLELP-PSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVT 2695
Query: 674 GNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKD 733
V + STSS PE P+ + T+ I G G P +L K
Sbjct: 2696 AEVAA--PSTSSSATSSPE---GPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKL 2750
Query: 734 PNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPG 793
P ++++++ E ++ Q GA + V + +PG
Sbjct: 2751 PG-------------RLVTVVEEKE------LVRRRRQQRGAAS--TLVPGVSETSASPG 2789
Query: 794 LPGCQTKELSLWKPT--GPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQ 851
P ++ P GP P S+ PT Q P+ + +G++ G
Sbjct: 2790 SPSVRSMSGPESSPPIGGPCEAAPSSSL---PTPPQ------QPFIARRHIELGVTGGGS 2840
Query: 852 LTPSQGA--PIRPTSVVSEFSGVP--SLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKT 907
GA I P +V P + S ++A G+ E DPV +T
Sbjct: 2841 PENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPET 2900
Query: 908 CRIAAKPYEEQVNPVLLTLSPQ 929
+A E Q+ P L PQ
Sbjct: 2901 LIVADPVLEPQLIPGPQPLGPQ 2922
Score = 67.8 bits (164), Expect = 9e-11
Identities = 139/584 (23%), Positives = 207/584 (35%), Gaps = 135/584 (23%)
Query: 199 LPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSG---LVPVQVATSVPAP------- 248
+P P P P AS P ++P VP+S P P+ ++PV + S P P
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS 2495
Query: 249 SPPLAPVPALAP-----APPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPA 303
SP P PA P PP+ L++ S+PL + VP+ AS +PL A
Sbjct: 2496 SPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPP-SVPISASVT---NLPLGLRPEA 2551
Query: 304 PLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAA-------PAPPSVP 356
L A P +L A V S+ T L+ VP L P+ P + P+ PS+
Sbjct: 2552 ELCAQALASPESLELASV-ASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLT 2610
Query: 357 MPT---------PTPSSGPPSTPTLIPAFAPTP--------VPAPTPAPIFTPAPTPMPA 399
+ P S +T T++P P + P A P P+ A
Sbjct: 2611 LEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEA 2670
Query: 400 ------ATPAAIPTSAP-IPASFSLSRVCFP--AAQAPAMQKVPLSFQPGTVLT------ 444
T A PTS+P P + V P ++ A + + P +P T
Sbjct: 2671 DRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEI 2730
Query: 445 -------PSQPLVYIPPPSC-----GQPLSV---------------ATLPTTLGVSSTLT 477
P QP P P G+ ++V A GVS T
Sbjct: 2731 RGQGTGRPGQP----PGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSA 2786
Query: 478 LPVLPSYLQDRCLPGVLASP------------ELRSYPYAFSVAR------------PLT 513
P PS R + G +SP L + P +AR P
Sbjct: 2787 SPGSPSV---RSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPEN 2843
Query: 514 SDSKLVSL---EVNRLPCTSPSGSTTTQPAPDGV-PGPLADTSLVTASAKVLPTPQPLLP 569
D L+++ V R P + + A GV P + T A +P P+ L+
Sbjct: 2844 GDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIV 2903
Query: 570 APSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL------- 622
A P P G + +PL SP + +R PP+ ++P+
Sbjct: 2904 ADPVLEPQLIPGPQPLGPQPVHRP-----NPLLSPVE-KRRRGRPPKARDLPIPGTISSA 2957
Query: 623 -DLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRS 665
D +S+S Q P P+ P ++ P T + + + +S S
Sbjct: 2958 GDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTS 3001
Score = 39.3 bits (90), Expect = 0.033
Identities = 58/211 (27%), Positives = 72/211 (34%), Gaps = 48/211 (22%)
Query: 244 SVPAPSPPL------APVPALAPAPPSVPTLISDSNPLSVS----------ASVLVPVPA 287
S P SPP+ AP +L P PP P + L V+ A + + PA
Sbjct: 2797 SGPESSPPIGGPCEAAPSSSL-PTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPA 2855
Query: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQA------PVPPSAPTLVLAPVPTPVLAPM 341
G P +PA V P + ++ PVP +V PV P L P
Sbjct: 2856 VKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPG 2915
Query: 342 PASTPPAAPAPPSVPMPTPTP-----SSGPPSTPTL-IPA-------------FAPTPVP 382
P P P P P P +P PP L IP P P P
Sbjct: 2916 P---QPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHP 2972
Query: 383 AP-TPAP--IFTPAPTPMPAATPAAIPTSAP 410
+P TP P + P T T I TS P
Sbjct: 2973 SPLTPLPPLLVCPTATVANTVTTVTISTSPP 3003
Score = 32.0 bits (71), Expect = 5.3
Identities = 43/166 (25%), Positives = 66/166 (39%), Gaps = 32/166 (19%)
Query: 163 DSRQGVGEKNTFILATLGTGV-PVEG--TL----PLVTTNFSPLPAPICP-----PAPGS 210
D+ +GV E + L G PV G TL P++ P P P+ P P P
Sbjct: 2872 DAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLL 2931
Query: 211 ASVPHS----VPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVP 266
+ V P A +P +P + +G + T P PL P+P L P +
Sbjct: 2932 SPVEKRRRGRPPKARDLP--IPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTA-- 2987
Query: 267 TLISDSNPLSVSASVLVPVPASAPPS---GPVPLSAPAPAPLSVPV 309
+V+ +V +++PP G P + P+P P +PV
Sbjct: 2988 ---------TVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPV 3024
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 135 bits (339), Expect = 4e-31
Identities = 186/875 (21%), Positives = 298/875 (34%), Gaps = 146/875 (16%)
Query: 176 LATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPD------AFQVPLSVPA 229
+ T T P P ++T +P P P + S P + P P + P+
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501
Query: 230 PVPHSGLVPVQVATSVP---APSPP----LAPVPALAPAPPSVPTLISDSNPLSVSASVL 282
P + + P T++P PSPP P P P+PP+ T I+ +
Sbjct: 1502 PPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT-TPITPPTSTTTLPPTT 1560
Query: 283 VPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP---PSAPTLVLAPVPTPVLA 339
P P + P P + P+P + P +PP P P PS PT P P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTP--SPPTITTTTPPPTTTPSPPT-TTTTTPPPTTT 1617
Query: 340 PMPASTPPAAPAPPSVPM-PTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMP 398
P P +T P P + + PT TPS P +T T P P+P TP+P T TP P
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Query: 399 AATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQP---------- 448
TP++ T+ P P + +++ P+ + + P + TPS P
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTT---PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 449 ---------LVYIPPPSCGQPLSVATLPTTLG-------VSSTLTLPVLP---------- 482
+ +PP + PL+ LP ++ ++T T P +P
Sbjct: 1735 TTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDS 1794
Query: 483 ------------SYLQDRCLPGVLASPELRSYPYA--------------FSVARPLTSDS 516
+ D C PG A+ R+ Y SV ++
Sbjct: 1795 GKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNED 1854
Query: 517 K----------LVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQP 566
+ ++ E+N C + TT P P T+ +T + V PTP P
Sbjct: 1855 QKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTP-PTTTPITTTTTVTPTPTP 1913
Query: 567 L-----LPAPSGSSAPPHPAKMPSGTEQQTE---GTSVTFSPLKSPPQLEREMASPPECS 618
P ++ P P+GT+ T T+ T +P +P + +P +
Sbjct: 1914 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 1973
Query: 619 EMPLDLSSKSNRQ---KLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGN 675
+ + Q P+ P P T T + ++T + + T
Sbjct: 1974 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2033
Query: 676 VTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIP---GTYVGVANPVPASLLLNK 732
T+ +T++ P P+T +T ++ P GT P+ + +
Sbjct: 2034 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2093
Query: 733 DPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAP 792
P + P P ++ P GT Q +T TP P
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGT---------QTPTTTPITTTTTVTP---TP 2141
Query: 793 GLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQL 852
G QT PT I +V PT T +P + ++ + G
Sbjct: 2142 TPTGTQT-------PT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2193
Query: 853 TPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLP-------EGQPRPGGSFVPEQDPVTKN 905
TP+ PI T+ V+ P+ + ++ P P P G+ P P+T
Sbjct: 2194 TPTT-TPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249
Query: 906 KTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPS 940
T P Q T +P T T ++ P+
Sbjct: 2250 TTVTPTPTPTGTQTP----TTTPITTTTTVTPTPT 2280
Score = 128 bits (322), Expect = 4e-29
Identities = 170/792 (21%), Positives = 267/792 (33%), Gaps = 88/792 (11%)
Query: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPA 247
T TT +P P P + P P Q P + P + + P T
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPTPTPTGTQT 1941
Query: 248 P-SPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLS 306
P + P+ + P P T + P++ + +V P P P + P +
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTT 1998
Query: 307 VPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
V + P P T + P PTP P +T P P PTPT + P
Sbjct: 1999 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTPTPTPTGTQTP 2057
Query: 367 PSTP-TLIPAFAPTPVPAPTPAPIFTP-----APTPMPAATPAAIPTSAPIPASFSLSRV 420
+TP T PTP P T P TP TP P T PT+ PI + +++
Sbjct: 2058 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2117
Query: 421 CFP-AAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLP 479
P Q P + + T +TP+ P P+ Q + + TT V+ T T
Sbjct: 2118 PTPTGTQTPTTTPITTT----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT-- 2165
Query: 480 VLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPS 532
P+ Q + + + P P T+ + + P T+P
Sbjct: 2166 --PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223
Query: 533 GSTTT---QPAPDGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMP 584
+TTT P P G P T+ +T + V PTP P P ++ P P
Sbjct: 2224 TTTTTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2281
Query: 585 SGTEQQTE---GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQ 638
+GT+ T T+ T +P +P + +P + + + Q P+
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341
Query: 639 RKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGD 698
P P T T + ++T + + T T+ +T++ P
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2401
Query: 699 PSTWVKNSTALISTIP---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIID 755
P+T +T ++ P GT P+ + + P + P P ++
Sbjct: 2402 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2461
Query: 756 QGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYP 815
P GT Q +T TP P G QT PT I
Sbjct: 2462 TPTPTGT---------QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITT 2501
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSL 875
+V PT T +P + ++ + G TP+ PI T+ V+ P+
Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTP 2557
Query: 876 SSSEAVHGLP-------EGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSP 928
+ ++ P P P G+ P P+T T P Q T +P
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTP 2613
Query: 929 QTGTLALSVQPS 940
T T ++ P+
Sbjct: 2614 ITTTTTVTPTPT 2625
Score = 124 bits (312), Expect = 6e-28
Identities = 178/849 (20%), Positives = 285/849 (33%), Gaps = 103/849 (12%)
Query: 142 TPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTN-FSPLP 200
TP+ T + +P G + + + T TG T P+ TT +P P
Sbjct: 2359 TPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417
Query: 201 APICPPAPGSASV-------PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSP-PL 252
P P + + P P Q P + P + + P T P+ P+
Sbjct: 2418 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPI 2476
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAP 312
+ P P T + P++ + +V P P P + P +V +
Sbjct: 2477 TTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPT 2533
Query: 313 PLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTL 372
P P T + P PTP P +TP + P PTPT + P +TP
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPIT 2592
Query: 373 IPAFAPTPVPAPTPAPIFTPAPTPM---------PAATPAAIPTSAPIPASFSLSRVCFP 423
T P PTP TP TP+ P T PT+ PI + +++ P
Sbjct: 2593 TTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2649
Query: 424 -AAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
Q P + + T +TP+ P P+ Q + + TT V+ T T P
Sbjct: 2650 TGTQTPTTTPITTT----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT----P 2695
Query: 483 SYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPSGST 535
+ Q + + + P P T+ + + P T+P +T
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755
Query: 536 TT---QPAPDGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMPSGT 587
TT P P G P T+ +T + V PTP P P ++ P P+GT
Sbjct: 2756 TTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813
Query: 588 EQQTE---GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQRKT 641
+ T T+ T +P +P + +P + + + Q P+
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2873
Query: 642 PPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
P P T T + ++T + + T T+ +T++ P P+T
Sbjct: 2874 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933
Query: 702 WVKNSTALISTIP---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGE 758
+T ++ P GT P+ + + P + P P ++
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993
Query: 759 PKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCS 818
P GT Q +T TP P G QT PT I +
Sbjct: 2994 PTGT---------QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTT 3033
Query: 819 VNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSS 878
V PT T +P + ++ + G TP+ PI T+ V+ P+ + +
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTPTGT 3089
Query: 879 EAVHGLP-------EGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTG 931
+ P P P G+ P P+T T P Q T +P T
Sbjct: 3090 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITT 3145
Query: 932 TLALSVQPS 940
T ++ P+
Sbjct: 3146 TTTVTPTPT 3154
Score = 124 bits (312), Expect = 6e-28
Identities = 178/849 (20%), Positives = 285/849 (33%), Gaps = 103/849 (12%)
Query: 142 TPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTN-FSPLP 200
TP+ T + +P G + + + T TG T P+ TT +P P
Sbjct: 2911 TPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969
Query: 201 APICPPAPGSASV-------PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSP-PL 252
P P + + P P Q P + P + + P T P+ P+
Sbjct: 2970 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPI 3028
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAP 312
+ P P T + P++ + +V P P P + P +V +
Sbjct: 3029 TTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPT 3085
Query: 313 PLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTL 372
P P T + P PTP P +TP + P PTPT + P +TP
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPIT 3144
Query: 373 IPAFAPTPVPAPTPAPIFTPAPTPM---------PAATPAAIPTSAPIPASFSLSRVCFP 423
T P PTP TP TP+ P T PT+ PI + +++ P
Sbjct: 3145 TTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3201
Query: 424 -AAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
Q P + + T +TP+ P P+ Q + + TT V+ T T P
Sbjct: 3202 TGTQTPTTTPITTT----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT----P 3247
Query: 483 SYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPSGST 535
+ Q + + + P P T+ + + P T+P +T
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3307
Query: 536 TT---QPAPDGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMPSGT 587
TT P P G P T+ +T + V PTP P P ++ P P+GT
Sbjct: 3308 TTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3365
Query: 588 EQQTE---GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQRKT 641
+ T T+ T +P +P + +P + + + Q P+
Sbjct: 3366 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3425
Query: 642 PPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
P P T T + ++T + + T T+ +T++ P P+T
Sbjct: 3426 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 702 WVKNSTALISTIP---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGE 758
+T ++ P GT P+ + + P + P P ++
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545
Query: 759 PKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCS 818
P GT Q +T TP P G QT PT I +
Sbjct: 3546 PTGT---------QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTT 3585
Query: 819 VNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSS 878
V PT T +P + ++ + G TP+ PI T+ V+ P+ + +
Sbjct: 3586 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTPTGT 3641
Query: 879 EAVHGLP-------EGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTG 931
+ P P P G+ P P+T T P Q T +P T
Sbjct: 3642 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITT 3697
Query: 932 TLALSVQPS 940
T ++ P+
Sbjct: 3698 TTTVTPTPT 3706
Score = 124 bits (310), Expect = 1e-27
Identities = 182/856 (21%), Positives = 290/856 (33%), Gaps = 108/856 (12%)
Query: 142 TPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTN-FSPLP 200
TP+ T + +P G + + + T TG T P+ TT +P P
Sbjct: 3463 TPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521
Query: 201 APICPPAPGSASV-------PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSP-PL 252
P P + + P P Q P + P + + P T P+ P+
Sbjct: 3522 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPI 3580
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAP 312
+ P P T + P++ + +V P P P + P +V +
Sbjct: 3581 TTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPT 3637
Query: 313 PLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTL 372
P P T + P PTP P +TP + P PTPT + P +TP
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPIT 3696
Query: 373 IPAFAPTPVPAPTPAPIFTPAPTPM---------PAATPAAIPTSAPIPASFSLSRVCFP 423
T P PTP TP TP+ P T PT+ PI + +++ P
Sbjct: 3697 TTT---TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3753
Query: 424 -AAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
Q P + + T +TP+ P P+ Q + + TT V+ T T P
Sbjct: 3754 TGTQTPTTTPITTT----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT----P 3799
Query: 483 SYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPSGST 535
+ Q + + + P P T+ + + P T+P +T
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3859
Query: 536 TT---QPAPDGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMPSGT 587
TT P P G P T+ +T + V PTP P P ++ P P+GT
Sbjct: 3860 TTVTPTPTPTGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3917
Query: 588 EQQTE---GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQRKT 641
+ T T+ T +P +P + +P + + + Q P+
Sbjct: 3918 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3977
Query: 642 PPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
P P T T + ++T + + T T+ +T++ P P+T
Sbjct: 3978 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4037
Query: 702 WVKNSTALISTIP---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGE 758
+T ++ P GT P+ + + P + P P ++
Sbjct: 4038 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4097
Query: 759 PKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCS 818
P GT Q +T TP P G QT PT I +
Sbjct: 4098 PTGT---------QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTT 4137
Query: 819 VNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEF-------SG 871
V PT T +P + ++ + G TP+ PI T+ V+ +G
Sbjct: 4138 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPTPTGTQTG 4196
Query: 872 VPSLSSSEAVHGLPEGQPRPGGSFVPE-----QDPVTKNKTCRIAAKPYEEQVNPVLLTL 926
P+ +S+ + L P P S P+ P+T++ T P E + T
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESS-TPQTSRSTSSPLTESTTLLSTLPPAIEMTS----TA 4251
Query: 927 SPQTGTLALSVQPSGG 942
P T T + SGG
Sbjct: 4252 PPSTPTAPTTT--SGG 4265
Score = 123 bits (308), Expect = 2e-27
Identities = 116/420 (27%), Positives = 158/420 (37%), Gaps = 56/420 (13%)
Query: 192 VTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVP---AP 248
+TT P P PP + P + P + P P P+ T+ P P
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS-PPITTTTTPPPTTTP 1454
Query: 249 SPPLA----PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP-PSGPVPLSAPAPA 303
SPP++ P P P+PP+ + P + + P P + P P P++ PA
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 304 PLSVPVS--APPLALIQAPVP---PSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP 358
P + +PP P P PS PT PT P +TP P + P P
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLS 418
T TPS +TP+ TP P TP+P T TP P TP+ PT+ PI S +
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPTSTT 1633
Query: 419 RVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLP--TTLGVSSTL 476
+ P P+ + P T TPS P P P P++ T P TT S
Sbjct: 1634 TL--PPTTTPSPPPTTTTTPPPTT-TPSPPTTTTPSP----PITTTTTPPPTTTPSSPIT 1686
Query: 477 TLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTT 536
T P P+ + +P + P + P+T+ T+PS +TT
Sbjct: 1687 TTPSPPTT--------TMTTPSPTTTP-----SSPITTT-------------TTPSSTTT 1720
Query: 537 TQPAPDGV--PGPLADTSLVTASAKVLP---TPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
P P + P P S T + LP T PL P S P P P T T
Sbjct: 1721 PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP-PTFSPFSTTTPT 1779
Score = 118 bits (295), Expect = 6e-26
Identities = 189/833 (22%), Positives = 276/833 (33%), Gaps = 139/833 (16%)
Query: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVP- 246
TLP TT P PP P + P P + P+P + P T P
Sbjct: 1415 TLPPTTTPSPPTTTTTTPP-PTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473
Query: 247 ---------APSPPLA----PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSG 293
PSPP P P P+PP+ + ++ ++ + P P + +
Sbjct: 1474 TTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT-TPSPPTTTTTT 1532
Query: 294 PVPLSAPAP---APLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAP 350
P P + P+P P++ P S L P PP PT P PT +P +TP
Sbjct: 1533 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--PTTTTTPPPTTTPSPPTTTTPSPPT 1590
Query: 351 APPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPM--PAATPAAIPTS 408
+ P PT TPS PP+T T P TP P PT PI P T P TP+ PT+
Sbjct: 1591 ITTTTPPPTTTPS--PPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTTPSPPPTT 1647
Query: 409 APIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL--VYIPPPSCGQPLSVATL 466
P P P+ P T TPS P+ PPP+ + T
Sbjct: 1648 TTTP----------PPTTTPS---------PPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688
Query: 467 P----TTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLE 522
P TT+ S T P P + P +P P + P T+ S +
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSP--ITTTTTPSSTTTPS--PPPTTMTTPSPTTTPSPPTTTM 1744
Query: 523 VNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLP---------TPQPLLPAPSG 573
P T+ S TTT P P + S T + +P + +P P G
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGG 1804
Query: 574 SS------------------APPHPAKMPSGTEQQTEGTSVTFSPL-KSPPQ-------- 606
+ A +P +P G QT V+ + K+ Q
Sbjct: 1805 DTELIGDVCGPGWAANISCRATMYP-DVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPM 1863
Query: 607 ---LEREM-ASPPECSEMPLDLSSKSNRQKLP---LPNQRKTPPMPVLTPVHTSSKALLS 659
L E+ EC P +++ + P P T P TP T +
Sbjct: 1864 AFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTP 1923
Query: 660 TVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNG--DPSTWVKNSTALISTIP--- 714
+ + T G T ++ + P G P+T +T ++ P
Sbjct: 1924 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 1983
Query: 715 GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAG 774
GT P+ + + P + P P ++ P GT Q
Sbjct: 1984 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT---------QTP 2034
Query: 775 AEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWS 834
+T TP P G QT PT I +V PT T +
Sbjct: 2035 TTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTTVTPTPTPTGTQTPTTT 2083
Query: 835 PYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLP-------EG 887
P + ++ + G TP+ PI T+ V+ P+ + ++ P
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTP 2139
Query: 888 QPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPS 940
P P G+ P P+T T P Q T +P T T ++ P+
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPT 2188
Score = 113 bits (283), Expect = 1e-24
Identities = 111/406 (27%), Positives = 154/406 (37%), Gaps = 50/406 (12%)
Query: 224 PLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLV 283
P + P+P P S T P + P P P+PP T +
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT--------TTPPPTTT 1453
Query: 284 PVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA 343
P P + + P P + P+P P + P +PP P PP+ T P TP P
Sbjct: 1454 PSPPISTTTTPPPTTTPSP-PTTTP--SPPTT---TPSPPTTTTTTPPPTTTP---SPPT 1504
Query: 344 STPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTP----------A 393
+TP PA + PT TPS PP+T T P TP P PT PI P
Sbjct: 1505 TTPITPPASTTTLPPTTTPS--PPTTTTTTPPPTTTPSP-PTTTPITPPTSTTTLPPTTT 1561
Query: 394 PTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP 453
P+P P T PT+ P P + + P P P T T + P P
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP---SPPTTTTTTPPPTTTP 1618
Query: 454 PPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLT 513
P P++ T TTL ++T P P P SP + P + P+T
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTT---PSPPPTTTTTPPPTTTPSPPTTTTP-----SPPIT 1670
Query: 514 SDSKLVSLEVNRLPCT---SPSGSTTTQPAPDGVP-GPLADTSLVTASAKVLPTPQP-LL 568
+ + P T SP +T T P+P P P+ T+ T S+ P+P P +
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPI--TTTTTPSSTTTPSPPPTTM 1728
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
PS ++ P P + T + +T +PL PP + SP
Sbjct: 1729 TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPL--PPSITPPTFSP 1772
Score = 108 bits (269), Expect = 6e-23
Identities = 102/398 (25%), Positives = 143/398 (35%), Gaps = 32/398 (8%)
Query: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPM 357
S P P P S L P PP+ T P P P P T P P + P
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTT----PPPTTTPSPPITTTTTPPPTTTPS 1455
Query: 358 PTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSL 417
P + ++ PP T T P P TP+P T TP P TP+ PT+ PI S
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP-PTTTPITPPAST 1514
Query: 418 SRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLT 477
+ + P P+ P T T + P P P P++ T TTL ++T
Sbjct: 1515 TTL--PPTTTPS---------PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT-- 1561
Query: 478 LPVLPSYLQDRCLPGVLASPELRSYPYAFSVAR----PLTSDSKLVSLEVNRLPCTSPSG 533
P P P SP + P ++ P T+ S + P T+PS
Sbjct: 1562 -PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP 1620
Query: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEG 593
TTT P L T+ + TP P ++ P P + T T
Sbjct: 1621 PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT 1680
Query: 594 TSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTS 653
S + SPP SP P+ ++ + P P PP + TP T+
Sbjct: 1681 PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP-----PPTTMTTPSPTT 1735
Query: 654 SKALLSTVLSRSQRTTQAAGGNVT----SCLGSTSSPF 687
+ + +T ++ TT ++ T S T SPF
Sbjct: 1736 TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773
Score = 104 bits (259), Expect = 8e-22
Identities = 128/563 (22%), Positives = 185/563 (32%), Gaps = 90/563 (15%)
Query: 142 TPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTN-FSPLP 200
TP+ T + +P G + + + T TG T P+ TT +P P
Sbjct: 3923 TPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3981
Query: 201 APICPPAPGSASV-------PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSP-PL 252
P P + + P P Q P + P + + P T P+ P+
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQTPTTTPI 4040
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAP 312
+ P P T + P++ + +V P P P + P +V +
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTPT 4097
Query: 313 PLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTP-T 371
P P T + P PTP P +TP + P PTPT + P +TP T
Sbjct: 4098 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPIT 4156
Query: 372 LIPAFAPTPVPAPTPAPIFTP-------APTPMPAATPAAIPT----------------- 407
PTP P T P TP PTP P T PT
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216
Query: 408 -----------SAPIPASFSLSRVCFPAAQA-----PAMQKVPLSFQPGTVLTPSQPLVY 451
S+P+ S +L PA + P+ P + G L+P
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTT 4276
Query: 452 IPP--PSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVA 509
PP P+ G ++ PT V +T T P+ P ++ + LR YP
Sbjct: 4277 SPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP-LSTPSIIRTTGLRPYP------ 4329
Query: 510 RPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTS-LVTASAKVL------P 562
S L+ +N T P + G DT V S
Sbjct: 4330 -----SSVLICCVLN---------DTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWS 4375
Query: 563 TPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL 622
P P P+ S + P P+K S + T GT P PP+ E E +C
Sbjct: 4376 CPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQENETWWLCDC----F 4431
Query: 623 DLSSKSNRQKLPLPNQRKTPPMP 645
+ K N + + + PPMP
Sbjct: 4432 MATCKYNNTVEIVKVECEPPPMP 4454
Score = 103 bits (258), Expect = 1e-21
Identities = 150/720 (20%), Positives = 241/720 (33%), Gaps = 87/720 (12%)
Query: 263 PSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP 322
P+ T + NP + + + P P P P++ + P
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941
Query: 323 PSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPV- 381
P+ + TP P TP P + + TPTP+ TPT P T V
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVT 2000
Query: 382 PAPTPAPIFTPAPTPM---------PAATPAAIPTSAPIPASFSLSRVCFP-AAQAPAMQ 431
P PTP TP TP+ P T PT+ PI + +++ P Q P
Sbjct: 2001 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2060
Query: 432 KVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLP 491
+ + T +TP+ P P+ Q + + TT V+ T T P+ Q
Sbjct: 2061 PITTT----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT----PTGTQTPTTT 2106
Query: 492 GVLASPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPSGSTTT---QPAP 541
+ + + P P T+ + + P T+P +TTT P P
Sbjct: 2107 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 542 DGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMPSGTEQQTE---G 593
G P T+ +T + V PTP P P ++ P P+GT+ T
Sbjct: 2167 TGTQTP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2224
Query: 594 TSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQRKTPPMPVLTPV 650
T+ T +P +P + +P + + + Q P+ P P T
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2284
Query: 651 HTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALI 710
T + ++T + + T T+ +T++ P P+T +T +
Sbjct: 2285 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2344
Query: 711 STIP---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCG 767
+ P GT P+ + + P + P P ++ P GT
Sbjct: 2345 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT----- 2399
Query: 768 KKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQ 827
Q +T TP P G QT PT I +V PT T
Sbjct: 2400 ----QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTTVTPTPTPTG 2444
Query: 828 VLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLP-- 885
+P + ++ + G TP+ PI T+ V+ P+ + ++ P
Sbjct: 2445 TQTPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTPTGTQTPTTTPIT 2500
Query: 886 -----EGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPS 940
P P G+ P P+T T P Q T +P T T ++ P+
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPT 2556
Score = 100 bits (249), Expect = 1e-20
Identities = 109/421 (25%), Positives = 156/421 (37%), Gaps = 70/421 (16%)
Query: 332 PVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVP----APTPA 387
P+ + P P +T P+ P + +P PT + PP+T T P TP P TP
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLP-PTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449
Query: 388 PIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQ 447
P TP+P TP PT+ P P + + S P P+ + P T TPS
Sbjct: 1450 PTTTPSPPISTTTTPP--PTTTPSPPTTTPS----PPTTTPSPPTTTTTTPPPTT-TPSP 1502
Query: 448 PLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFS 507
P P P S TLP T S T P P SP
Sbjct: 1503 PTTTPITP----PASTTTLPPTTTPSPPTTTTTTPP-------PTTTPSP---------P 1542
Query: 508 VARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADT-----SLVTASAKVLP 562
P+T + +L P SP +TTT P P P P T ++ T +
Sbjct: 1543 TTTPITPPTSTTTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600
Query: 563 TPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL 622
TP P P + ++ PP P T T TS T P + P + PP + P
Sbjct: 1601 TPSP--PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP------SPPPTTTTTPP 1652
Query: 623 DLSSKSNRQKLPLPNQRKTPPMPVLT------------PVHTSSKALLSTVLSRSQRTTQ 670
++ P P TP P+ T P+ T+ +T+ + S TT
Sbjct: 1653 PTTT-------PSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705
Query: 671 AAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVG---VANPVPAS 727
++ T+ ST++P P + P+T T ++T+P T P+P S
Sbjct: 1706 SSPITTTTTPSSTTTPSPP-PTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Query: 728 L 728
+
Sbjct: 1765 I 1765
Score = 86.3 bits (212), Expect = 2e-16
Identities = 173/836 (20%), Positives = 269/836 (32%), Gaps = 128/836 (15%)
Query: 188 TLPLVTTNFSPLPAPICPPA-----PGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVA 242
T P TT SP+ PP P + P S P S P P +
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733
Query: 243 TSVPAPS-------PPLAPVPALA--PAPPSVPTLISDSNPLSVSASVLVPV-------- 285
T+ P+P PP L P PPS+ + + VP+
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLD 1793
Query: 286 ---PASAPPSGPVPLSAPAPAP-LSVPVSAPPLALIQAPVPPSAPTLVLA---------- 331
P P G L P + +S P+ T+V
Sbjct: 1794 SGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNE 1853
Query: 332 -PVPTPVLAPMP-------------ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFA 377
P V+ PM T P + PTP ++ +T T+ P
Sbjct: 1854 DQKPGGVI-PMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPT 1912
Query: 378 PTPVPAPTPAPIFTPAP-TPMPAATPAAIPTSAPIPASFSLSRVCFP-AAQAPAMQKVPL 435
PT PT PI T TP P T PT+ PI + +++ P Q P +
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1972
Query: 436 SFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLA 495
+ T +TP+ P P+ Q + + TT V+ T T P+ Q +
Sbjct: 1973 T----TTVTPT------PTPTGTQTPTTTPITTTTTVTPTPT----PTGTQTPTTTPITT 2018
Query: 496 SPELRSYPYAFSVARPLTSDSKLVSLEV-------NRLPCTSPSGSTTT---QPAPDGVP 545
+ + P P T+ + + P T+P +TTT P P G
Sbjct: 2019 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2078
Query: 546 GPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHPAKMPSGTEQQTE---GTSVT 597
P T+ +T + V PTP P P ++ P P+GT+ T T+ T
Sbjct: 2079 TP--TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136
Query: 598 FSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ---KLPLPNQRKTPPMPVLTPVHTSS 654
+P +P + +P + + + Q P+ P P T T +
Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2196
Query: 655 KALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIP 714
++T + + T T+ +T++ P P+T +T ++ P
Sbjct: 2197 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256
Query: 715 ---GTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGS 771
GT P+ + + P + P P ++ P GT
Sbjct: 2257 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT--------- 2307
Query: 772 QAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPV 831
Q +T TP P G QT PT I +V PT T
Sbjct: 2308 QTPTTTPITTTTTVTP---TPTPTGTQT-------PT-TTPITTTTTVTPTPTPTGTQTP 2356
Query: 832 GWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLP------ 885
+P + ++ + G TP+ PI T+ V+ P+ + ++ P
Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTP---TPTPTGTQTPTTTPITTTTT 2412
Query: 886 -EGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPS 940
P P G+ P P+T T P Q T +P T T ++ P+
Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPT 2464
Score = 45.8 bits (107), Expect = 4e-04
Identities = 85/423 (20%), Positives = 127/423 (30%), Gaps = 55/423 (13%)
Query: 525 RLPCTSPSGSTTTQPAPDGV---PGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPP--- 578
R+ C P T P+P P P + T+L + PT P P+ + +PP
Sbjct: 1385 RVNCCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITT 1444
Query: 579 HPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQ 638
P+ T T+ T P +P SPP + P + P
Sbjct: 1445 TTTPPPTTTPSPPISTTTTPPPTTTP--------SPPTTTPSPPTTTPSPPTTTTTTPPP 1496
Query: 639 RKTPPMPVLTPV--HTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRN 696
TP P TP+ S+ L T TT T+ T++P + P
Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTP-ITPPTSTTT 1555
Query: 697 GDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQ 756
P+T +T P T P P + P + P P +
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPT----TTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 757 GEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPR 816
P T + P T TP LP PT + P
Sbjct: 1612 PPPTTTPS--------------PPTTTPITPPTSTTTLP-----------PTTTPSPPPT 1646
Query: 817 CSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLS 876
+ PT+T P +P + + + +P P PT+ ++ S + S
Sbjct: 1647 TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS 1706
Query: 877 SSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALS 936
S P P P +T + P + TL P T + L+
Sbjct: 1707 SPITTTTTPSSTTTPS----PPPTTMTTPSPTTTPSPP-----TTTMTTLPPTTTSSPLT 1757
Query: 937 VQP 939
P
Sbjct: 1758 TTP 1760
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 130 bits (328), Expect = 8e-30
Identities = 223/894 (24%), Positives = 312/894 (34%), Gaps = 149/894 (16%)
Query: 114 PLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNT 173
P P + A+ S++ + + S +PL +S Q P + +G ++
Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826
Query: 174 FILATLGTGVPVEGTLPLVTTNFSPLPAPI-CPPAPGSASVPHSVPDAFQVPLSVPAPVP 232
+ + +P E +L + SP PP+P A P +V PLS P
Sbjct: 827 PVSPVEASFLP-ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV-----TPLS-----P 875
Query: 233 HSGLVPVQVATSVPAPSPPLAPVPA---LAPAPPSVPTLISDSNPLSVSASVLVP--VPA 287
+P + P PS P P PAP P L S+ + + P +PA
Sbjct: 876 KGVTLPPK---ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPA 932
Query: 288 SAPPSG-PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSA--PTLVLAPV-PTPVLAPMP- 342
S P G P P +A P+P P + P AP PP+A P+ P P+P AP P
Sbjct: 933 SPSPKGAPTPPAATPPSPKGGPATPSPK---WAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 343 ASTPP------AAPAPPSVPMPT----PTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTP 392
A+TPP A P+P P P P+P P +TP P A TP A P+P +P
Sbjct: 990 AATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP--FPKGASTPPAATPPSPKGSP 1047
Query: 393 APTPMPAATP----AAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQP 448
A TP+P P A +P+ PA+ SL P A P K + P P P
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA-TPSPKGAPMPP 1106
Query: 449 LVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSV 508
P P G +AT P ++ P P G LA+P + P +
Sbjct: 1107 AATPPSPKGG----LATPPHKGAPTTPAATPPSPK--------GGLATPPPKGAPTTPAA 1154
Query: 509 ARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLL 568
P SP G T P P G P T A P+P+ L
Sbjct: 1155 TPP------------------SPKGGLAT-PPPKGAP---------TTPAATPPSPKGGL 1186
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
PS AP PA P +G T SP +P A+PP S
Sbjct: 1187 ATPSPKGAPTTPAATP----PSPKGGLATPSPKGAP---TTPAATPP------------S 1227
Query: 629 NRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAA------GGNVTSCLGS 682
+ L P+ + P P TP S K +T + T AA GG T
Sbjct: 1228 PKGGLATPSPKGAPTTPAATP--PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285
Query: 683 TSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDP 742
+P V+ P + G ++ K + + P + G P
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP----------------- 1328
Query: 743 RHLPKQEPI-SIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKE 801
PK P + PKGT S G PS+ + TP P G
Sbjct: 1329 ---PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 802 LSLWKPTGPANIYPRCSVNGKPTSTQVLPVG--WSPYHQASLLSIGISSAGQLTPSQGAP 859
K GPA P+ G PTS V+P+ +P + S G LTP P
Sbjct: 1386 PPSPK-RGPAIPSPK----GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP 1440
Query: 860 I--RPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEE 917
+ + S G P+ SS+ LP P P++ P K ++ P +
Sbjct: 1441 VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS-----PKEPPAPKQ--VATSSSPKKA 1493
Query: 918 QVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGA 971
P + + S + + P + L S TP P+ A
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547
Score = 129 bits (324), Expect = 2e-29
Identities = 199/795 (25%), Positives = 283/795 (35%), Gaps = 91/795 (11%)
Query: 197 SPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV--PVQVATSVPAPSPPLAP 254
+P P PP+P S A P + P P P GL P + A + PA +PP +P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPP-SP 1136
Query: 255 VPALAPAPPSVPTLISDSNPLSVSASVLVP-------VPASAPPSGPVPLSAPAP--APL 305
LA PP + P S + P PA+ PPS L+ P+P AP
Sbjct: 1137 KGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPT 1196
Query: 306 SVPVSAP-PLALIQAPVPPSAPTLVLAPVPTP---VLAPMP-------ASTPPAAPAPPS 354
+ + P P + P P APT A P+P + P P A+TPP+ P+
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA 1256
Query: 355 VPMPTPTPSSGPPSTPTLIPAFAPTPVP-APTPAPIFTPAPTPMPAATPAAIPTSAPIPA 413
P P P+ + P+L A P AP PA + P+P PA +P P AP P
Sbjct: 1257 TPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP---PKGAPTP- 1312
Query: 414 SFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVS 473
PAA P+ + P + P TP P V P P G P AT P++ G
Sbjct: 1313 ---------PAATPPSPKGSPGTPPPKGAPTP--PAVTPPSPK-GTPTLPATTPSSKGGP 1360
Query: 474 STLTL---PVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTS 530
+T + P P+ + P + P S TS + ++ L + P T
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA-VIPLSPKKAPATP 1419
Query: 531 PSGSTTTQPAP-DGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSA-----PPHPAKMP 584
+ P+ D P + SL A A P P P+ G PP P + P
Sbjct: 1420 VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP 1479
Query: 585 S----GTEQQTEGTSVTFSPLKSP------PQLEREMASPPECSEMPLDLSSKSNRQKLP 634
+ T + T +P+ +P P +E+ + P P+ ++ +K P
Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Query: 635 LPNQRK--------TPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSP 686
K T P P TP + K +T S+ + A ++ G+ S
Sbjct: 1540 ATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV--TPSTYKGAPSPK 1597
Query: 687 FVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLP 746
++ P V + P + T T P G A P P + +D P
Sbjct: 1598 ELLIPPAVTSPSPK---EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654
Query: 747 KQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWK 806
+ P+ + KKG A E + TP AP G QTK+ S
Sbjct: 1655 ASVTCKM-GATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATS 1713
Query: 807 PTGPANIYPRCSVNGK-PTST----QVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIR 861
P P P K P ST +LPV A S G L P +
Sbjct: 1714 P--PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST 1771
Query: 862 PTSVVSEFSGVPSLSSSEAVHGLPEG------QPRPGGSFVPEQD--PVTKNKTCRIAAK 913
P + + F V S +V P P P + P+Q P + +K
Sbjct: 1772 PLTAAA-FEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830
Query: 914 PYEEQVNPVLLTLSP 928
P LL L P
Sbjct: 1831 PLAPADEDELLPLIP 1845
Score = 93.6 bits (231), Expect = 1e-18
Identities = 203/830 (24%), Positives = 297/830 (35%), Gaps = 150/830 (18%)
Query: 182 GVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL---VP 238
G P +TT P P+ AP ++ S + ++PLS A + L +P
Sbjct: 541 GAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLP 600
Query: 239 V-QVATSVPAP------------------------------SPPLAPVPALAPAPPSV-P 266
+ + A+S+ +P +P +A P + P V P
Sbjct: 601 IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAP 660
Query: 267 TLISDSNPLSVSASVLVPVPAS-APPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSA 325
T ++ + +AS + S AP + PV PL VP ++ + +P A
Sbjct: 661 TTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL-VPTASENCPVAPSPQNTCA 719
Query: 326 P--TLVLAP-----VPTPVLAPMPASTPP-----------AAPAP-PSVPMPTPTPSSGP 366
P TLVLAP VP+P L PA TPP +A AP S P PT SG
Sbjct: 720 PLATLVLAPEIPKSVPSPSLP--PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGA 777
Query: 367 PSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQ 426
+T + + A +P+P+ + +P P ++ P +LS P +
Sbjct: 778 SATAS---SKGTLTYLADSPSPLGV-SVSPQTKRPPTKKGSAGPDTPIGNLSSPVSP-VE 832
Query: 427 APAMQKVPLSFQ-----PGTVLTPSQPLVY-IPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
A + + LSFQ P T +P+ P P PS PLS + + T ++
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 481 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540
LP + P +P L + AR + + + P +P+ T P+
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK---GIPASPSPKGAPTPPAATPPS 949
Query: 541 PDGVPGPLADTSLVTASAKVLPTPQ--PLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTF 598
P G P + T A P+P+ P P+P G+ P P+ T +G T
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTP------PAATPPSPKGGPATP 1003
Query: 599 SPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALL 658
SP +P +PP S K + P P TPP P S A
Sbjct: 1004 SPKGAPTP---PAVTPP---------SPKGSPAATPFPKGASTPP-AATPPSPKGSPA-- 1048
Query: 659 STVLSRSQRTTQAA------GGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS-TALIS 711
+T L + TT AA GG T L +P P + G + K + +
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAA 1108
Query: 712 TIPGTYVGVANP-------VPASLLLNKDPNLGLNRDPRHLPKQEPIS-IIDQGEPKGTG 763
T P G+A P PA+ P GL P PK P + PKG
Sbjct: 1109 TPPSPKGGLATPPHKGAPTTPAA--TPPSPKGGLATPP---PKGAPTTPAATPPSPKGGL 1163
Query: 764 ATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKP 823
AT KG+ P + K P G T + P P S G P
Sbjct: 1164 ATPPPKGAPTTPAATPPSPK---GGLATPSPKGAPTTPAA--TPPSPKGGLATPSPKGAP 1218
Query: 824 TSTQVLPVGWSPYHQASLLSIGISSAGQLTPS-QGAPIRPTSVVSEFSGVPSLSSSEAVH 882
T+ P SP G TPS +GAP P + G P+
Sbjct: 1219 TTPAATPP--SP------------KGGLATPSPKGAPTTPAATPPSPKGGPATPP----- 1259
Query: 883 GLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLT-LSPQTG 931
P+G P P + P + +A P++ NP ++T SP+ G
Sbjct: 1260 --PKGAPTPPAATPP-------SLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Score = 91.7 bits (226), Expect = 6e-18
Identities = 191/791 (24%), Positives = 292/791 (36%), Gaps = 160/791 (20%)
Query: 237 VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVP 296
+P + +VPA L P P + ++ S+ LSV+A++ P P PP P P
Sbjct: 1 MPGEATETVPATEQEL-------PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP 53
Query: 297 LSAP-------APAPLSVPVSAPPLALIQAPVPPSAPTLVL-------APVPTPVLAPMP 342
P +P P +++ PL + P P S+ L AP P L P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPL---EVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP 110
Query: 343 ASTPPAAPAPPSV-PMPTPTPSSGPPSTPTLIPAFAPTPVPAPT--PAPIFTPAPTPMPA 399
S A A P + P TPSS S P + A AP V + P + T P+ A
Sbjct: 111 ISPAALALASPMIAPTLKGTPSS---SAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVA 167
Query: 400 ATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQP-LVYIPPPSCG 458
+ + I SAPI P+ + KVP P TPS P +V P C
Sbjct: 168 ESGSVITLSAPIA----------PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV 217
Query: 459 QPLS-----VATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLT 513
P++ VA+LP T + T TL + ++D + VL SP+ P + S+ P++
Sbjct: 218 TPMASIQSGVASLPQT---TPTTTLAIASPQVKDTTISSVLISPQ---NPGSLSLKGPVS 271
Query: 514 SDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVP------------------------GP-- 547
+ L SL LP + S T P P GP
Sbjct: 272 PPAAL-SLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSA 330
Query: 548 LADTSLVTAS------AKVLPTPQPLL-PAPSGSSAPP-----HPAKMPSGTEQQTEGTS 595
L+D ++ T S P+ + ++ P PS + P P PS + + +S
Sbjct: 331 LSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISS 390
Query: 596 VTFSP-------------------LKSPPQLERE---MASPPECS--EMPLDLSSKSNRQ 631
+T SP LKS P +A P S PL +++
Sbjct: 391 ITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIA 450
Query: 632 KLPLPNQR----KTPPM---PVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTS 684
P +PPM P+ TS AL+ ++ + +TQ V + L
Sbjct: 451 AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQ-----VATTLRIPV 505
Query: 685 SPFVIFPEIVRNGDPSTWVKNSTAL-ISTIPGTYVGVA-NPVPASLLLNKDPNL--GLNR 740
SP + PE ++N S VK T + T+P + G +P A L KDP + +
Sbjct: 506 SPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA 565
Query: 741 DPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTK 800
P++ P + S + P AT KK + G+P + G P
Sbjct: 566 APKNSPSFQSTSSSPE-IPLSPEATLAKK-----SLGEPLPI----------GKPASSM- 608
Query: 801 ELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPI 860
T P + SV T + P P ++SL++ + +A L + A +
Sbjct: 609 -------TSPLGVNSSASV--IKTDSYAGPDSAGPLLKSSLITPTV-AAFPLESADPAGV 658
Query: 861 RPTSV--VSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQ 918
PT+ S ++ S V P+ P G+ T ++ C +A P
Sbjct: 659 APTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTC 718
Query: 919 VNPVLLTLSPQ 929
L L+P+
Sbjct: 719 APLATLVLAPE 729
Score = 81.3 bits (199), Expect = 8e-15
Identities = 144/609 (23%), Positives = 218/609 (35%), Gaps = 132/609 (21%)
Query: 92 PDDPQPKMDYAGNVAEAEGFLVPLSSPGDGLKLPASDSAEASNSRADCS---WTPLNTQM 148
P P PK D ++PLS P P + A+ S+ D + TP++ +
Sbjct: 1393 PAIPSPKGDPTSPA------VIPLS-PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
Query: 149 SKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPL-VTTNFSPLPAPICPPA 207
+ +P G A S +G L + P E P V T+ SP AP P
Sbjct: 1446 APATS-APKGGPATPSSKGDPT-----LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 208 PGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQ--------------------VATSVPA 247
G+ ++P +P + P VPA P S P+ + ++
Sbjct: 1500 MGAPTLPAVIPSS---PKEVPA-TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 248 PSP---PLAPVPALAPAPP-----SVPTLISDS--------NPLSVSASVLVPVPASAPP 291
PSP P P P APA P S P ++ S L + +V P P AP
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT 1615
Query: 292 ----SGPVPLSAPA-PAPLSVPVSAP--PLALIQAPVPPSAPTLVLAPVPTPVLAPMPAS 344
+ P P PA PAP P S P P +L +P P++ T + +PA
Sbjct: 1616 PPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAK 1675
Query: 345 TPP-------AAPAPPSVPMPTPTPSSGPPS--TPTLIPAFAPTP-VPAPTPAPIFTPAP 394
P APAP S P+ T GP + + P P P + P+ T AP
Sbjct: 1676 KGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAP 1735
Query: 395 TPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPP 454
P+ P+ S + A+ +P P + T LT + +P
Sbjct: 1736 APL-----------LPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPK 1784
Query: 455 PSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTS 514
P + SV+ P S ++LP+ PS P P+ + P + + S
Sbjct: 1785 P---ESASVSAAP-----SPPVSLPLAPS-------PVPTLPPKQQFLPSSPGLVLESPS 1829
Query: 515 DSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGS 574
+ E LP P +P GVP ++ T + +P P P +
Sbjct: 1830 KPLAPADEDELLPLIPP------EPISGGVPFQSVLVNMPTPKSAGIPVPTP------SA 1877
Query: 575 SAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLER-----------EMASPPECSEMPLD 623
P SGTE ++ +S P+LE ++A+ E E P+
Sbjct: 1878 KQPVTKNNKGSGTESDSD---------ESVPELEEQDSTQATTQQAQLAAAAEIDEEPVS 1928
Query: 624 LSSKSNRQK 632
+ +S +K
Sbjct: 1929 KAKQSRSEK 1937
Score = 77.4 bits (189), Expect = 1e-13
Identities = 236/1015 (23%), Positives = 353/1015 (34%), Gaps = 189/1015 (18%)
Query: 199 LPAPICPPAPGSA--SVPHSV---PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA 253
L API P P + VP V P P + + VP+ + P+ S A P
Sbjct: 175 LSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT 234
Query: 254 PVPALAPAPPSVP------TLISDSNPLSVSASVLVPVPAS---APPSGPVPLSAPAPAP 304
P LA A P V LIS NP S+S V PA+ + S PV S+ A
Sbjct: 235 PTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAG 294
Query: 305 LSVPVSAP-PLALIQAPVPPSA-----------PTLVLAPVPTPVLAPMPASTPPAAPAP 352
+ P P L AP+ S+ P+ + P ++ +ST + P+
Sbjct: 295 PNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPT-VKTISVDHSSTGASYPSQ 353
Query: 353 PSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPT-PMPAATPAAI-PTSAP 410
SV P P+ + P+T P AP+ P+ T +P+ + AT ++ PT++
Sbjct: 354 RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSL 413
Query: 411 IPASFSLSRVCFP-AAQAP--AMQKVPL--------------SFQPGTVLTP---SQPLV 450
I S + +P AQ P ++ PL +F+ T ++P S P+
Sbjct: 414 ILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPIS 473
Query: 451 YIPP--PSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLAS------------ 496
I P P+ VA + V++TL +PV P L + +S
Sbjct: 474 NIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQ 533
Query: 497 ---PELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTT---------------- 537
L P++ + A T V V P SPS +T+
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKK 593
Query: 538 ---QPAPDGVPGPLADTSL-VTASAKVLPTPQPLLPAPSGS-----------SAPPHPAK 582
+P P G P + L V +SA V+ T P +G +A P +
Sbjct: 594 SLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESA 653
Query: 583 MPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPE--------CSEMPLDLSSKSNRQKLP 634
P+G T + T++ S P LE ++ P+ + +PL ++ N P
Sbjct: 654 DPAGVAPTTAKGTSTYTTTAS-PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAP 712
Query: 635 LPNQR--------------KTPPMPVLTPVHT-----------SSKALLSTVLSRSQRTT 669
P K+ P P L P T + AL S + T
Sbjct: 713 SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPT 772
Query: 670 QAAGGNVT--------------SCLGSTSSPFVIFPEIVR-NGDPSTWVKNSTALISTIP 714
+ +G + T S LG + SP P + + P T + N ++ +S +
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832
Query: 715 GTYV---------------GVANPVPASLLLNKDPNLGLNRDPRHL---PKQEPI-SIID 755
+++ +P P S P+ P+ + PK+ P S+++
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 756 QGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYP 815
PK AT K + A + S K AR P G PT PA P
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKK----ARATPAPKGIPASPSPKGAPTPPAATPP 948
Query: 816 RCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPS-QGAPIRPTSVVSEFSGVPS 874
S G P + W+P A+ + G TPS +GAP P + G P+
Sbjct: 949 --SPKGGPATPS---PKWAPTPPAA--TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPA 1001
Query: 875 LSSSEAVHGLPE-GQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTL---SPQT 930
S + P P P GS P P K + AA P + +P L +P T
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGS--PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 931 GTLALSVQPSGGDIRMNQGPEESESHLCSDST---PKMEGPQGACGLKLAGDTKPKNQVL 987
L P GG + + S P P+GA A PK L
Sbjct: 1060 PAATLP-SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG-L 1117
Query: 988 ATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQLGS 1042
AT H+ TP P P+ L P S +G P G+
Sbjct: 1118 AT-PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 121 bits (304), Expect = 5e-27
Identities = 128/446 (28%), Positives = 167/446 (37%), Gaps = 62/446 (13%)
Query: 188 TLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV--PHSGLVPVQVATSV 245
T P T + P P PPA S + +P PL+ P P P L P+Q S
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPL-QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSP 636
Query: 246 PAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPL 305
PA SPPL+P+ +P P+ + P S S V P S P S PV SA P+
Sbjct: 637 PA-SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 695
Query: 306 SVPVSAPPLALIQAPV--PPSAPTLVLAPVPTPVLAPMPASTPPAAPA----------PP 353
++APPL + +P PP +P+ P P LA P PP+ PA PP
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755
Query: 354 SV-PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPI- 411
V P+ P PPS P +P +P P P P P + PA+ P AP
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLP-MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 412 -PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP--PPSCGQPLSVATLPT 468
AS +S + P QAP + PL P + P+ P + P PP+ G SV+
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVS---- 868
Query: 469 TLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPC 528
G TL L P R L+ P+L + S S + E R
Sbjct: 869 --GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH-----------SSSATSTPEELRGYD 915
Query: 529 TSPSGSTTTQPAPDG----------VPGPLADTSLVTASAKVLPTPQPLLPAPSG----- 573
+ P G P PD GP + A LP P P +
Sbjct: 916 SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI 975
Query: 574 ------SSAPPHPAKMPSGTEQQTEG 593
SA P P + G T G
Sbjct: 976 YETEGPESATPAPGALDPGPSPGTSG 1001
Score = 119 bits (298), Expect = 3e-26
Identities = 155/581 (26%), Positives = 216/581 (37%), Gaps = 105/581 (18%)
Query: 114 PLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVD--CSPAGVKALDSRQGVGEK 171
P S+P D L A S AS PL T +S V SP + L +
Sbjct: 447 PASTPPDSPPLQAPLSLPAS--------PPLQTSLSPAVSPLSSPLTIHPLQALSS---- 494
Query: 172 NTFILATLGTGVPVEGTL--PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPL---S 226
LA+ P+ + PL T + P+ PPA + ++P PL S
Sbjct: 495 ----LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 227 VPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVP 286
P PH P PAP P AP L PP P+ I
Sbjct: 551 APLTTPHLETPPC------PAPCPLQAPPSPLTTPPPETPSSI----------------- 587
Query: 287 ASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTP 346
A+ PP P L++P PL + +PPL+ + P P + P L L P+ P P P ++P
Sbjct: 588 ATPPPQAPPALASP---PLQ-GLPSPPLSPLATPPPQAPPXLALPPLQAP---PSPPASP 640
Query: 347 PAAP-APPSVPMPT-------PTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMP 398
P +P A PS P P S PPS P P F+P P +P+ P
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSL 699
Query: 399 AATPAAIPTSAPIPASFSLSRVCFPAAQA-PAMQKVPLSFQPGTVLTPSQPLVYIPPPSC 457
AA P +P S PAS +S P QA P + PL P +P PPP
Sbjct: 700 AAPPLQVPPSP--PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 458 GQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR---SYPYAFSVARPLTS 514
P +A P + S +LP+ P P LA+P L+ S P +F P +
Sbjct: 758 --PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 815
Query: 515 DSKL---------------VSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAK 559
+ L ++ + ++P + P+ T P PGP DTS+
Sbjct: 816 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP--DTSVSGPRLT 873
Query: 560 VLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLE--------REM 611
+ P P PP P++ PS T + + S +P +L
Sbjct: 874 LALAPGP----------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 923
Query: 612 ASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHT 652
ASPP +E+ + +R P R P P+ P T
Sbjct: 924 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 964
Score = 116 bits (291), Expect = 2e-25
Identities = 161/542 (29%), Positives = 214/542 (39%), Gaps = 95/542 (17%)
Query: 179 LGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSV----PAPVPHS 234
L T +P+ P + LP+P P P S + P Q P S+ P VPHS
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSP--PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 235 GLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVS-----ASVLVPV-PAS 288
P S+ AP PLA A PTL + + L++S AS+ P PAS
Sbjct: 395 LTSP-----SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
Query: 289 APPSGP---VPLS-----------APAPAPLSVPVSAPPLALIQ--APVPPSAP--TLVL 330
PP P PLS +PA +PLS P++ PL + A P AP +L++
Sbjct: 450 TPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509
Query: 331 APVPTPV-LAPMPASTPPAAPAPP---SVPMPTPTP---SSGPPSTPTLI--PAFAPTPV 381
P+ T LAP TPPA+ P ++P P P +S P +TP L P AP P+
Sbjct: 510 PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569
Query: 382 PAP----------TPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQA-PAM 430
AP TP+ I TP P PA A P +P S LS + P QA P +
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPA---LASPPLQGLP-SPPLSPLATPPPQAPPXL 625
Query: 431 QKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATL----------PTTLGVSSTLTLPV 480
PL P +P + P P L+V L P S + PV
Sbjct: 626 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 685
Query: 481 LPSYLQDRCLPGVLASPELR-------SYPYAFSVARPLTSDSKLVS--LEVNRLPCTSP 531
PS P LA+P L+ S P + S P + L + L+V P SP
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745
Query: 532 SGSTTTQPAPDGVPGPLADTSL-----------VTASAKVLPTPQPLLPAPSGSSAPPHP 580
S + P P VP LA L ++ AK P P L P + P P
Sbjct: 746 PMSPSATP-PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Query: 581 AKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRK 640
A P G + S+ SPL +PP + + P P +S + L P +
Sbjct: 805 ASFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT----LQAPRRPP 859
Query: 641 TP 642
TP
Sbjct: 860 TP 861
Score = 94.7 bits (234), Expect = 7e-19
Identities = 144/572 (25%), Positives = 212/572 (37%), Gaps = 66/572 (11%)
Query: 96 QPKMDYAGNVAEAEGFLVPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCS 155
+P + AG + G +P S+P G A S+ SR S +K
Sbjct: 56 KPLAERAGGIG---GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG 112
Query: 156 PA---GVKALDSRQG-VGEKNTFILAT------LGTGVPVEGTLPLVTTNFSPLPAPICP 205
P G + +R G +G+K I A T P L + P P
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GT 171
Query: 206 PAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSV 265
P+P A + +P P+ P + + S + P PA P +
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
Query: 266 PTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA----PAPLSVPVSAPPLALIQAPV 321
L ++ S++ + PA + PS APA P P + PP + P
Sbjct: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ--VTPPR 289
Query: 322 PPSAPTLVLAPVPT-PVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTP 380
+AP L P+ + P+ P P+ T A P PP TP P++ PPS P P P
Sbjct: 290 KDAAPAL--GPLSSSPLATPSPSGTK-ARPVPPPDNAATPLPATLPPSPPLATP--LPLA 344
Query: 381 VPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPG 440
P+P+ P P+P PA P+ P S P P P++Q +P P
Sbjct: 345 PPSPSAPPSLQTLPSP-PATPPSQAPPSMTTP----------PMQAPPSLQTIPPIQVPH 393
Query: 441 TVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYL--QDRCLPGVLASPE 498
++ +PS PPS PL++++L T + S TL S+L R L SP
Sbjct: 394 SLTSPSLQ----APPS---PLALSSLQATTSLGSP-TLQATHSFLTMSPRQTQASLTSP- 444
Query: 499 LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASA 558
+RP ++ L+ SP T+ PA + PL L S+
Sbjct: 445 ----------SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 559 KVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPP-EC 617
L + P P S P + QT S+T PL++ P L A PP +
Sbjct: 495 --LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSL----APPPLQT 548
Query: 618 SEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTP 649
+ PL + P P + PP P+ TP
Sbjct: 549 ASAPL-TTPHLETPPCPAPCPLQAPPSPLTTP 579
Score = 57.8 bits (138), Expect = 9e-08
Identities = 126/489 (25%), Positives = 168/489 (34%), Gaps = 101/489 (20%)
Query: 238 PVQVATSVPAPSPPLAPVPALAPAPPSVPTLIS--------DSNPLSVSASVL--VPVPA 287
P A + P PP +P P PP P + PL+ A + +P
Sbjct: 17 PAARAPGLLTPRPPGSP----RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPAS--T 345
SAP +GP + A P S PP + PP+ T P PV +P AS T
Sbjct: 73 SAPRAGP---TRSAGTSSRNPASRPPASGRGERAPPAKNTS-----PGPVSSPGRASGTT 124
Query: 346 PPA----------------------APAPPSVPMPTPTPSSGP-PSTPTLIPA----FAP 378
P AP ++ +SGP P TP+ A A
Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
Query: 379 TPVPAPTPAPIFTPAPT------------------PMPAAT--PAAIPTSAPIPASFSLS 418
T V P PAP P P P PAA P+A PAS SLS
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-GGGLQRPASRSLS 243
Query: 419 RVCFPAAQAPAMQKVPLSFQPGTVLTPSQP----LVYIPPPSCGQPLSVATLPTTLGVSS 474
P + +PA P PSQP L + PP P A P +SS
Sbjct: 244 SSATPLS-SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSS 301
Query: 475 TLTLPVLPSYLQDRCLPGV--LASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPS 532
+ PS + R +P A+P + P + +A PL P S
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP----------PSPSAP 351
Query: 533 GSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS-------APPHPAKMPS 585
S T P+P P A S+ T + P+ Q + P S APP P + S
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSS 411
Query: 586 GTEQQTEGT---SVTFSPLK-SPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKT 641
+ G+ T S L SP Q + + SP + P D LP +T
Sbjct: 412 LQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQT 471
Query: 642 PPMPVLTPV 650
P ++P+
Sbjct: 472 SLSPAVSPL 480
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 119 bits (297), Expect = 3e-26
Identities = 155/587 (26%), Positives = 212/587 (36%), Gaps = 112/587 (19%)
Query: 70 NARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDGLKLPASDS 129
+AR P + + SE +P P + G P S P S
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 130 AEASNSRADCSWTPLNTQMSKQVDCSPAGVKAL----------DSRQGVGEKNTFILATL 179
A + S P + K P G++AL D+ +G ++ LAT
Sbjct: 253 ARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
Query: 180 GTGVPVEG----TLPLVTTNFS-----PLPAPICPPAPGSASVPHSVPDAFQVPLSVPAP 230
++ TLP + S P P+ PP+P S P S+ P + P+
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP---SAPPSLQTLPSPPATPPSQ 364
Query: 231 VPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP 290
S P AT PSPPL+P LA PP P ++ +P P AP
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSP---LATPPPQAPPALA------------LP-PLQAP 408
Query: 291 PSGPVPLSAPAPAPLSVPVSAPPLAL----IQAPVPPSAPTLVLAPVPTPVLAPMPASTP 346
PS P ++P +PL+ P P AL +QAP P V AP P P+ S
Sbjct: 409 PSPP---ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
Query: 347 PAAPAPPSVPMP----TPTPSSGPPSTPTLI-PAFAPTPVPAPTPAPIFTPAPTPMPA-- 399
P + APPS+ P P+P + PP +P+ P AP P+ AP P + P P PA
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALA 524
Query: 400 --------ATPAAIPTSAPI--PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL 449
+ PA+ P AP AS +S + P QAP + PL P + P+ P
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS--PPASPT 582
Query: 450 VYIP--PPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFS 507
+ P PP+ G SV+ G TL L P R L+ P+L +
Sbjct: 583 LQAPRRPPTPGPDTSVS------GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH----- 631
Query: 508 VARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDG----------VPGPLADTSLVTAS 557
S S + E R + P G P PD GP + A
Sbjct: 632 ------SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685
Query: 558 AKVLPTPQPLLPAPSG-----------SSAPPHPAKMPSGTEQQTEG 593
LP P P + SA P P + G T G
Sbjct: 686 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732
Score = 112 bits (279), Expect = 4e-24
Identities = 135/489 (27%), Positives = 192/489 (39%), Gaps = 65/489 (13%)
Query: 195 NFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAP 254
+ S P+ PA S P A P S P P L P QV +P L P
Sbjct: 241 SLSSSATPLSSPARSGPSA-RGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 255 V---PALAPAPPSV------PTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPL 305
+ P P+P + PTL + + S++ + P+P + P P P+P
Sbjct: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
Query: 306 SVPVSAPPLAL----IQA-----PVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA-PPSV 355
+ P S +L +QA P PP +P P P LA P PP+ PA PP
Sbjct: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
Query: 356 PMPTPTPSSGPPSTPTLIPA-FAPTPVPAPTPAPIFTPAPTPM-PAATPAAIPTSAPIPA 413
P+ TP+P + L+ A F+P P P P AP PA P+ P+ATP P+ AP
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATP---PSQAP--- 471
Query: 414 SFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQ-PLVYIPPPSCGQPLSVATLPTTLGV 472
P+ AP +Q VP S ++PS P PPP PL +A P
Sbjct: 472 ---------PSLAAPPLQ-VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 473 S-STLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSP 531
+ +T L LPS PG S P + +A P +++ + ++P + P
Sbjct: 522 ALATPPLQALPS--PPASFPGQAPFSPSASLPMS-PLATPPPQAPPVLAAPLLQVPPSPP 578
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
+ T P PGP DTS+ + P P PP P++ PS T
Sbjct: 579 ASPTLQAPRRPPTPGP--DTSVSGPRLTLALAPGP----------PPPPSRSPSSTLSGP 626
Query: 592 EGTSVTFSPLKSPPQLE--------REMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPP 643
+ + S +P +L ASPP +E+ + +R P R P
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
Query: 644 MPVLTPVHT 652
P+ P T
Sbjct: 687 APLPWPPAT 695
Score = 93.6 bits (231), Expect = 1e-18
Identities = 141/482 (29%), Positives = 183/482 (37%), Gaps = 116/482 (24%)
Query: 198 PLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV----PHSG----------LVPVQVAT 243
P PAP P P + SV A + + P+P P +G L
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
Query: 244 SVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPA 303
S PA S P A APA PS P P + A + P PP +APA
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQP------KPKGLQA---LRPPQVTPPRKD---AAPALG 297
Query: 304 PLSV-PVSAP-PLALIQAPVPPSAPTLVLAPVPTPVLA-PMPASTPPAAPAPPSVPMPTP 360
PLS P++ P P A +Q+ PP+ P + T LA P+P + PP+ APPS+
Sbjct: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA-PPSPSAPPSLQT--- 353
Query: 361 TPSSGPPSTPTLIPAFAPTPVPAPT--------PAPIFTPAPTPMPAATPAAI--PTSAP 410
PS PP+TP P+ A T + +PT P+P +P TP P A PA P AP
Sbjct: 354 LPS--PPATP---PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
Query: 411 I--PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPT 468
PAS LS + P+ QAP V L P + PPPS P
Sbjct: 409 PSPPASPPLSPLATPSPQAPNALAVHLLQAP-----------FSPPPSP---------PV 448
Query: 469 TLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPC 528
S + PV PS P LA+P L+ P P S P
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP------SPPAS------------PP 490
Query: 529 TSPSGSTTTQPAPD--------GVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHP 580
SPS + Q P P P A +L T + LP+P PA AP P
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP----PASFPGQAPFSP 546
Query: 581 AKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRK 640
+ S+ SPL +PP + + P P +S + L P +
Sbjct: 547 S------------ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT----LQAPRRPP 590
Query: 641 TP 642
TP
Sbjct: 591 TP 592
Score = 70.5 bits (171), Expect = 1e-11
Identities = 141/537 (26%), Positives = 188/537 (35%), Gaps = 89/537 (16%)
Query: 155 SPAGVKALDSRQGVGEKNTFILA------TLGTGVPVEG-TLPLVTTNFSPLPAPIC--- 204
+PA ++ L + VG K A T+ P G T T++ +P P
Sbjct: 40 TPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGR 99
Query: 205 ----PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL---VPVQVATSVPAPSPPLAPVPA 257
PPA ++ P S P + P P+ GL VA +P + + A
Sbjct: 100 GERAPPAKNTSPGPVSSPGRAS-GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 158
Query: 258 LAPAPPSVPTLISDSNPL---SVSASVLVPVPASAPPSGPVP----------------LS 298
A S PT + S + S +A V +P AP + P P +
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
Query: 299 APAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP 358
P+PA P + L Q P S + P+ +P + A P APA PS P P
Sbjct: 219 EPSPAARRRPSAGGGL---QRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLS 418
+ PP AP P + +P+ TP+P+ A A PT P S SL+
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSS-SPLATPSPSA--ALQSQAPPTLPATPHSSSLT 331
Query: 419 -RVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLT 477
++ P AP P S Q PS P PPS Q + PT S L
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQT----LPSPPAT---PPS--QATTSLGSPTLQATHSFLP 382
Query: 478 LPVL-PSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTT 536
P L P P LA P L++ P P SP S
Sbjct: 383 SPPLSPLATPPPQAPPALALPPLQAPPS----------------------PPASPPLSPL 420
Query: 537 TQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSV 596
P+P P LA L A P P P + AP S P P PS T S+
Sbjct: 421 ATPSPQA-PNALAVHLL---QAPFSPPPSPPVQAPF--SPPASPPVSPSATPPSQAPPSL 474
Query: 597 TFSPLKSPPQLERE-----MASPPECSEMPLDLSSKSNRQKLP-LPNQRKTPPMPVL 647
PL+ PP A+PP + PL + P P TPP+ L
Sbjct: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531
Score = 46.6 bits (109), Expect = 2e-04
Identities = 82/337 (24%), Positives = 124/337 (36%), Gaps = 28/337 (8%)
Query: 343 ASTPPAAPAPPSV-PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT 401
A+ PAA AP + P P +P PP TP + A P+ A A
Sbjct: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAG--AVGRKPLAERAGGIGGATI 70
Query: 402 PAAIPTSAPIPASFSLSRVCFPAAQAPAM---QKVP--LSFQPGTVLTPSQPLVYIPPPS 456
P + P + P ++ + SR PA++ PA ++ P + PG V +P + P
Sbjct: 71 PESAPRAGPTRSAGTSSRN--PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128
Query: 457 CGQPLSVATLPTTLGVSSTLTLP----VLPSYLQDRC-----LPGVLASPELRSYPYAFS 507
GQ + T+ P + +D P + R+
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
Query: 508 VARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPL 567
+ RP S E R +S S +TT+P+P P A L +++ L +
Sbjct: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 568 L--PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLS 625
L PA SG SA P ++ + +G P +PP+ + A P S PL
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATP 307
Query: 626 SKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVL 662
S S Q + PP TP +S L+T L
Sbjct: 308 SPS------AALQSQAPPTLPATPHSSSLTCQLATPL 338
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 118 bits (296), Expect = 4e-26
Identities = 90/238 (37%), Positives = 108/238 (45%), Gaps = 28/238 (11%)
Query: 197 SPLPAPICPPAPGSASVPHSVPDAFQ-VPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPV 255
+PLP P S S P +P VP S APVP S L PV +TS P P+ PLAPV
Sbjct: 1752 APLPPSTSASVPASTSAP--LPATLTPVPASTSAPVPASTLAPVLASTSAPVPASPLAPV 1809
Query: 256 PALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLA 315
A A SVSASV A+A S P SAPAP P+ VS P
Sbjct: 1810 SASA----------------SVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASV 1853
Query: 316 LIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLI-- 373
I A S P L A T P PA++ PAAP + +P P++ P P
Sbjct: 1854 TILASA--SIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASA 1911
Query: 374 PAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQ 431
PA APTPV AP PAP PAP A T P P+ + S+ P+ + P+ Q
Sbjct: 1912 PAPAPTPVSAPNPAP---PAPAQTQAQTHK--PVQNPLQTTSQSSKQPPPSIRLPSAQ 1964
Score = 94.0 bits (232), Expect = 1e-18
Identities = 190/784 (24%), Positives = 281/784 (35%), Gaps = 129/784 (16%)
Query: 173 TFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVP 232
T + A+ VP P++ + +P+PA P SASV SVPA
Sbjct: 1775 TPVPASTSAPVPASTLAPVLASTSAPVPASPLAPVSASASV----------SASVPASTS 1824
Query: 233 HSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSA----SVLVPVPAS 288
+ + S PAP+P LA V P SV L S S P+ SA S P PA+
Sbjct: 1825 AAAITSSSAPASAPAPTPILASV----STPASVTILASASIPILASALASTSAPTPAPAA 1880
Query: 289 APPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPA 348
+ P+ PV ++AP P S P ++ PLA A P APT V AP P P P PA T
Sbjct: 1881 SSPAAPV-ITAPT-IPASAPTASVPLAPASASAPAPAPTPVSAPNPAP---PAPAQTQAQ 1935
Query: 349 APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTP-----------VPAPTPAPIFTPAPTPM 397
P P+ T + SS P +P+ A TP + P T
Sbjct: 1936 THKPVQNPLQTTSQSSKQPPPSIRLPS-AQTPNGTDYVASGKSIQTPQSHGTLTAELWDN 1994
Query: 398 PAATPAAI--------PTSAPIPASFSL-SRVCFPAAQAPAMQKVPLSFQPGTVLTPSQP 448
A PA + P S P P S S ++ AP+ + + G + +
Sbjct: 1995 KVAPPAVLNDISKKLGPISPPQPPSVSAWNKPLTSFGSAPSSEGAKNGQESGLEI-GTDT 2053
Query: 449 LVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSV 508
+ + P S G V +PVL D+ PE +
Sbjct: 2054 IQFGAPASNGNENEV--------------VPVLSEKSADKI-------PEPKEQRQKQPR 2092
Query: 509 ARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLL 568
A P ++ +LP SP + +P P G L + + A +
Sbjct: 2093 AGP---------IKAQKLPDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPS 2143
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTE-GTSVTFSPLKSPPQLEREMAS-PPECSEMPLDLSS 626
PA S+ P + + +E TE GT ++ S + + + S +P +++
Sbjct: 2144 PATVRSTDPVTTKETKAVSEMSTEIGTMISVSSAEYGTNAKESVTDYTTPSSSLPNTVAT 2203
Query: 627 KSNRQK------LPLPNQRKTPPMPVLTPVHTSSK-------ALLSTVLSRSQRTTQAAG 673
+ + + +PLPN T P+P + SS T S R
Sbjct: 2204 NNTKMEDTLVNNVPLPN---TLPLPKRETIQQSSSLTSVPPTTFSLTFKMESARKAWENS 2260
Query: 674 GNVT---SCLGSTSSPFVIFPEIVRNGDPSTWVKNSTA--------LISTIPGTYVGVAN 722
NV S + ST+ P +G PST NS + + S P + A
Sbjct: 2261 PNVREKGSPVTSTAPPIATGVSSSASG-PSTANYNSFSSASMPQIPVASVTPTASLSGAG 2319
Query: 723 PVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTV 782
S L K DP ++ K +P + P + + A+ Q
Sbjct: 2320 TYTTSSLSTKSTT---TSDPPNICKVKPQQLQTSSLPSASHFSQLSCMPSLIAQ-QQQNP 2375
Query: 783 KRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVN--------GKPTSTQVLPVG-W 833
+ Y A +P L+ T A + P +PTS Q +P+ +
Sbjct: 2376 QVYVSQSAAAQIPAFYMDTSHLFN-TQHARLAPPSLAQQQGFQPGLSQPTSVQQIPIPIY 2434
Query: 834 SP---YHQASLLSIG----ISSAGQLTPSQGAPIR--PTSVVSEFSGVPSLSSSEAVHGL 884
+P HQA LS+G +S A +L S P R P + S S + S A+H
Sbjct: 2435 APLQGQHQAQ-LSLGAGPAVSQAQELFSSSLQPYRSQPAFMQSSLSQPSVVLSGTAIHNF 2493
Query: 885 PEGQ 888
P Q
Sbjct: 2494 PTVQ 2497
Score = 93.6 bits (231), Expect = 1e-18
Identities = 143/500 (28%), Positives = 184/500 (36%), Gaps = 69/500 (13%)
Query: 234 SGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSG 293
+G+ Q + SVP PLA AP PPS SV AS P+PA+ P
Sbjct: 1735 TGIQQAQSSASVP----PLAS----APLPPSTSA--------SVPASTSAPLPATLTP-- 1776
Query: 294 PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPV--PTPVLAPMPASTPPAAPA 351
VP S AP P S AP LA APVP S LAPV V A +PAST AA
Sbjct: 1777 -VPASTSAPVPAS--TLAPVLASTSAPVPASP----LAPVSASASVSASVPASTSAAAIT 1829
Query: 352 PPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIP--T 407
S P P PTP STP + A +P A T APTP PAA+ A P T
Sbjct: 1830 SSSAPASAPAPTPILASVSTPASVTILASASIPILASALASTSAPTPAPAASSPAAPVIT 1889
Query: 408 SAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTP-SQPLVYIPPPSCGQPLSVATL 466
+ IPAS + V A A A P TP S P P P+ Q + +
Sbjct: 1890 APTIPASAPTASVPLAPASASA---------PAPAPTPVSAPNPAPPAPAQTQAQTHKPV 1940
Query: 467 PTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRL 526
L +S + PS LP S+ P + + L N++
Sbjct: 1941 QNPLQTTSQSSKQPPPSIR----LPSAQTPNGTDYVASGKSIQTPQSHGTLTAELWDNKV 1996
Query: 527 PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSG 586
+ + + P P P V +PL S S+ SG
Sbjct: 1997 APPAVLNDISKKLGPISPPQP----------PSVSAWNKPLTSFGSAPSSEGAKNGQESG 2046
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDL--SSKSNRQKLPLPNQRKTPPM 644
E T+ ++ F +P E P SE D K RQK P K +
Sbjct: 2047 LEIGTD--TIQFG---APASNGNENEVVPVLSEKSADKIPEPKEQRQKQPRAGPIKAQKL 2101
Query: 645 PVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVK 704
P L+PV RS + + G P VR+ DP T K
Sbjct: 2102 PDLSPVENKEHKPGPIGKERSLKNRKVKDAQQVEPEGQEKPS----PATVRSTDPVT-TK 2156
Query: 705 NSTAL--ISTIPGTYVGVAN 722
+ A+ +ST GT + V++
Sbjct: 2157 ETKAVSEMSTEIGTMISVSS 2176
Score = 44.7 bits (104), Expect = 8e-04
Identities = 58/273 (21%), Positives = 106/273 (38%), Gaps = 39/273 (14%)
Query: 1108 DDVTESLPPKKMKCGKEKDSEEQQLQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGAS 1167
DD S PK+ +++ S+ + K S+ ++P+ P S K P G
Sbjct: 337 DDEQGSNSPKENN-SEDQGSKASENNENKKETDEVSNTKSSSQIPAQP--SVAKVPYG-- 391
Query: 1168 DSGKEHNGVRGKHKHRKPTK---------PESQS-PGK------RADSHEEGSLEKKAKS 1211
G N RG H P P+ Q+ PG+ + +E + K+ +
Sbjct: 392 -KGPSFNQERGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRR 450
Query: 1212 SFRDFIPVVLSTRTR---------SQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTP 1262
+ V R R Q + C+ D +G E P+ EE
Sbjct: 451 QQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIR----E 506
Query: 1263 AKRRKVRKTQRDTQYRSHHAQDKSLLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEE 1322
+R K R+ +++ + ++K R + +E+ E R+M E+E ++E
Sbjct: 507 REREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREM----EKERKQE 562
Query: 1323 EEGLLKRKKRRRQKSRKYQTGEYLTEQEDEQRR 1355
+E L+R+K + ++ +K + E E E E+ +
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREK 595
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 117 bits (294), Expect = 7e-26
Identities = 153/568 (26%), Positives = 203/568 (35%), Gaps = 104/568 (18%)
Query: 70 NARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDGLKLPASDS 129
+AR P + + SE +P P + G P S P S
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAA--RRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 130 AEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTL 189
A + S P + K P G++AL Q + P G L
Sbjct: 244 ARSGPSARGTPRAPAHPSQPK-----PKGLQALRPPQVTPPRKD--------AAPALGPL 290
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
+ SPL P P AP S S P S+ P + P+ S P AT PS
Sbjct: 291 -----SSSPLATP-SPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPV 309
PPL+P LA PP P ++ +P P APPS P ++P +PL+ P
Sbjct: 345 PPLSP---LATPPPQAPPALA------------LP-PLQAPPSPP---ASPPLSPLATPS 385
Query: 310 SAPPLAL----IQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP----TPT 361
P AL +QAP P V AP P P+ S P + APPS+ P P+
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445
Query: 362 PSSGPPSTPTLI-PAFAPTPVPAPTPAPIFTPAPTPMPA----------ATPAAIPTSAP 410
P + PP +P+ P AP P+ AP P + P P PA + PA+ P AP
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 504
Query: 411 I--PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP--PPSCGQPLSVATL 466
AS +S + P QAP + PL P + P+ P + P PP+ G SV+
Sbjct: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVS-- 560
Query: 467 PTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRL 526
G TL L P R L+ P+L + S S + E R
Sbjct: 561 ----GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH-----------SSSATSTPEELRG 605
Query: 527 PCTSPSGSTTTQPAPDG----------VPGPLADTSLVTASAKVLPTPQPLLPAPSG--- 573
+ P G P PD GP + A LP P P +
Sbjct: 606 YDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 665
Query: 574 --------SSAPPHPAKMPSGTEQQTEG 593
SA P P + G T G
Sbjct: 666 TIYETEGPESATPAPGALDPGPSPGTSG 693
Score = 93.2 bits (230), Expect = 2e-18
Identities = 132/461 (28%), Positives = 170/461 (36%), Gaps = 104/461 (22%)
Query: 198 PLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPA 257
P PAP P P + SV A + HS T+ P+P+ P
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASE----------HS--------TTEPSPAARRRPSAG 222
Query: 258 LAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA----PAPLSVPVSAPP 313
P+ +L S + PLS PA + PS APA P P + PP
Sbjct: 223 GGLQRPASRSLSSSATPLSS--------PARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274
Query: 314 LALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLI 373
+ P +AP L P+ + LA S PP+ APPS+ PS PP+TP
Sbjct: 275 Q--VTPPRKDAAPAL--GPLSSSPLATPSPSAPPSPSAPPSL---QTLPS--PPATP--- 322
Query: 374 PAFAPTPVPAPT--------PAPIFTPAPTPMPAATPAAI--PTSAP--IPASFSLSRVC 421
P+ A T + +PT P+P +P TP P A PA P AP PAS LS +
Sbjct: 323 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 382
Query: 422 FPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVL 481
P+ QAP V L P + PPPS P S + PV
Sbjct: 383 TPSPQAPNALAVHLLQAP-----------FSPPPS---------PPVQAPFSPPASPPVS 422
Query: 482 PSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAP 541
PS P LA+P L+ P P SP S + P P
Sbjct: 423 PSATPPSQAPPSLAAPPLQVPP----------------------SPPASPPMSPSATPPP 460
Query: 542 DGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPL 601
P PLA L AK P P L P + P PA P G + S+ SPL
Sbjct: 461 Q-APPPLAAPPL--QLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPMSPL 516
Query: 602 KSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTP 642
+PP + + P P +S + L P + TP
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPT----LQAPRRPPTP 553
Score = 62.8 bits (151), Expect = 3e-09
Identities = 132/517 (25%), Positives = 174/517 (33%), Gaps = 96/517 (18%)
Query: 238 PVQVATSVPAPSPPLAPVPALAPAPPSVPTLIS--------DSNPLSVSASVL--VPVPA 287
P A + P PP +P P PP P + PL+ A + +P
Sbjct: 17 PAARAPGLLTPRPPGSP----RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
Query: 288 SAPPSGPVPLSAP---------------APAPLSVPVSAP----PLALIQAPVPPSAPTL 328
SAP +GP S P +P P+S P A P L Q + SA
Sbjct: 73 SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 132
Query: 329 VLAPVPTPVLAPMPASTPPAAPAPPSVPMP-TPTPSSGPPSTPTLIPAFAPTPVPAPTPA 387
V T AP ++ A S P P TP+P+ S P P P+ P
Sbjct: 133 VARGKATE--APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 388 P--------------IFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKV 433
P T P+P P+A PAS SLS P + +PA
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSA-GGGLQRPASRSLSSSATPLS-SPARSGP 248
Query: 434 PLSFQPGTVLTPSQP----LVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRC 489
P PSQP L + PP P A P +SS+ PS
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSSSPLATPSPS-----A 302
Query: 490 LPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVP---- 545
P A P L++ P + P T S+ T+ GS T Q +P
Sbjct: 303 PPSPSAPPSLQTLP-----SPPATPPSQ----------ATTSLGSPTLQATHSFLPSPPL 347
Query: 546 GPLADTSLVTASAKVLPTPQPLLPAPSGSSAPP-HPAKMPSGTEQQTEGTSVTFSPLKSP 604
PLA A LP PL PS ++PP P PS + +P P
Sbjct: 348 SPLATPPPQAPPALALP---PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 605 PQLEREMASPPECSEMPLDLSSKSNRQKLPL---------PNQRKTPPM-PVLTPVHTSS 654
P + P S P+ S+ Q P P+ +PPM P TP +
Sbjct: 405 PSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 655 KALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFP 691
L + L ++ QA T L + SP FP
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 500
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 117 bits (293), Expect = 1e-25
Identities = 223/983 (22%), Positives = 369/983 (37%), Gaps = 138/983 (14%)
Query: 54 SSSFSKVELTAVGSGSNARGADPDGS--------ATEKLGHKSEDKPDDPQP---KMDYA 102
SSS + E+T++ + + + + P S A+ + G S D P +
Sbjct: 2789 SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKAS 2848
Query: 103 GNVAEAEGFLVPLSSPGDGLKL----PASDSAEASNSRADCSWTPLNTQMSKQVDCSPAG 158
+ AEG +VP+S+ +G L P S + AS+ + S TP++T + V S G
Sbjct: 2849 SSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIP--VTTSTEG 2906
Query: 159 VKALDSRQGVG-------EKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSA 211
+ + +G E +T + + L + VPV G+ + S P P SA
Sbjct: 2907 SSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGS---EASTLSTTPVDTRTPVTTSA 2963
Query: 212 SVPHS--VPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLI 269
S + +P+S P + L + V+T A S A + PA S P
Sbjct: 2964 EASSSPTTAEGTSMPISTPGE-RRTPLTSMSVSTMPVASSE--ASTLSRTPADTSTPVTT 3020
Query: 270 SDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLV 329
S S + + +P S P G PL+ S+PVS P+A+ P A TL
Sbjct: 3021 STEASSSPTTAEGTGIPISTPSEGSTPLT-------SIPVSTTPVAI------PEASTLS 3067
Query: 330 LAPVPT--PVLAPMPASTPPAAPAPPSVPMPTPTPSSGP---------PSTPTLIPAFAP 378
PV + PV+ S+ P S+P+ T + S P P T + I +
Sbjct: 3068 TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLST 3127
Query: 379 TPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQ 438
TPV TP T A + + ++PTS P S L+ + + + LS
Sbjct: 3128 TPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSAT 3187
Query: 439 PGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPE 498
P TP + + S+ T + G++ ++PV + + + +P
Sbjct: 3188 PVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPV 3247
Query: 499 LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASA 558
+ P S + S + E +P ++PS +T + +A + T S
Sbjct: 3248 DSNTPLTTST----EASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLST 3303
Query: 559 KVLPTPQPLLPAPSGSSAPP--HPAKMPSGT--EQQTEGTSVTFSPLKSPPQLEREMASP 614
T P+ SS+PP MP+ T E T T+++FS +++
Sbjct: 3304 TPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTT 3363
Query: 615 PECSEMPLDLSSKSNRQ-------KLPL--PNQRKTP--PMPV-LTPVHTS--------- 653
P + P+ S++++ +P P++ TP MPV TPV +S
Sbjct: 3364 PVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTP 3423
Query: 654 --SKALLSTVLSRSQRTTQAAGGNV-TSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALI 710
S L++T S T A G ++ TS S+P I P +T V +S A
Sbjct: 3424 VDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL------STTPVASSEA-- 3475
Query: 711 STIPGTYVGVANPVPASLLLNKDP---------------------NLGLNRDPRHLPKQE 749
ST+ T V + PV S N P N+ ++ P + E
Sbjct: 3476 STLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTP--VASSE 3533
Query: 750 PISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTG 809
++ T T + S + A Q +T++ TP+ G T LS T
Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSE---GSSSLTTMLLSSTYVTS 3590
Query: 810 PANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQL-TPSQGAPIRPTSVVSE 868
P + T S ++++ +S+ ++ TP P+ TSV
Sbjct: 3591 SEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTIS 3650
Query: 869 FSG----------VPSLSSSEAVHG--LPEGQPRPGGSFVPEQDPVTKN--KTCRIAAKP 914
+G P ++S++ PEG P + P+T T R+ +
Sbjct: 3651 EAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSE 3710
Query: 915 YEEQVNPVLLTLSP-QTGTLALS 936
P ++T +P T T A+S
Sbjct: 3711 GSTLSTPSVVTSTPVTTSTEAIS 3733
Score = 116 bits (291), Expect = 2e-25
Identities = 226/1007 (22%), Positives = 377/1007 (37%), Gaps = 152/1007 (15%)
Query: 108 AEGFLVPLSSPGDG----LKLPASDSAEASNSRADCSWTPLNTQM----SKQVDCSPAGV 159
A+G +P S+P +G +P S + S+ + S TPL+T S + CSP
Sbjct: 732 ADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTT 791
Query: 160 KALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPA-PICPPAPGSASVPHSVP 218
+ + + +L T +PV T P+ + S L P+ +P + S S
Sbjct: 792 EGTSMPISTPSEGSPLL----TSIPVSIT-PVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846
Query: 219 DAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAP--VPALAPAPPSVPTLISDSNPL- 275
S+P G P+ TS+P + +A + L+ P T +++S
Sbjct: 847 PTPAEGTSMPTSTYSEGRTPL---TSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEAR 903
Query: 276 -SVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVP 334
S + S +P S P G PL+ S+P S P+ +A + P PV
Sbjct: 904 SSPTTSEGTSMPTSTPGEGSTPLT-------SMPDSTTPVVSSEARTLSATPVDTSTPVT 956
Query: 335 TPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIP-----AFAPTPVPAPTPAPI 389
T A +T P S P TP + P + TL+ + TPV + TP
Sbjct: 957 TSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTT 1016
Query: 390 FTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL 449
T A +P P A ++PTS P S L+R+ + + LS P TP
Sbjct: 1017 STEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTP--VT 1074
Query: 450 VYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVA 509
Y S ++PT+ + L +P + R + AS L + P S+
Sbjct: 1075 TYSQASSSSTTADGTSMPTSTYSEGSTPLTSVP--VSTRLVVSSEAS-TLSTTPVDTSI- 1130
Query: 510 RPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPG----PLADTSLVTASAKVLPT-- 563
P+T+ S E + P T+ S T P +G P++ T +V++ A L T
Sbjct: 1131 -PVTT-----STEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTP 1184
Query: 564 --PQPLLPAPSGSSAPPHPAK---MPSGTEQQ-----------------TEGTSVTFSPL 601
+ + + +S+PP A+ MP+ T + +E ++++ SP+
Sbjct: 1185 VDSKTQVATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPV 1244
Query: 602 --KSPPQLEREMASPPECSE---MPLDLSSKSNRQKLPLPNQRKTPPMP-----VLTPVH 651
+P E +S P +E +P +S+ + +P P + TPV
Sbjct: 1245 DTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVD 1304
Query: 652 TSSKALLSTVLSR---------------SQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRN 696
T + S +S S+ T V + L ++S+ ++ V N
Sbjct: 1305 TKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDN 1364
Query: 697 GDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISI--I 754
P T + + +T GT + +NP + L P ++ P + +S +
Sbjct: 1365 STPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIP---VSTTPVVSSEASTLSATPV 1421
Query: 755 DQGEPKGTGATCGKKGSQAGAEGQPSTV--KRYTPARIAP----GLPGCQTKELSLWKPT 808
D P T A + A P++ + TP + P + + LS
Sbjct: 1422 DTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTTPVD 1481
Query: 809 GPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGA------PIRP 862
+ + +V+ PT A SI IS TPS+G+ P+
Sbjct: 1482 SNSPVVTSTAVSSSPT-------------PAEGTSIAIS-----TPSEGSTALTSIPVST 1523
Query: 863 TSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPV 922
T+V S S + SLS++ AV P S P T + T + Y E P
Sbjct: 1524 TTVAS--SEINSLSTTPAVTSTPVTTYSQASS-----SPTTADGT-SMQTSTYSEGSTP- 1574
Query: 923 LLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKP 982
LT P + L +S + + ++ P +S++ + + + + A G + T
Sbjct: 1575 -LTSLPVSTMLVVSSEAN----TLSTTPIDSKTQVTAST--EASSSTTAEGSSMTISTPS 1627
Query: 983 KNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSS 1029
+ L T + V TP P+ L P DS+ + V SS
Sbjct: 1628 EGSPLLTSIP---VSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS 1671
Score = 95.9 bits (237), Expect = 3e-19
Identities = 142/625 (22%), Positives = 234/625 (37%), Gaps = 63/625 (10%)
Query: 124 LPASDSAEASNSRADCSWTPLN--TQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGT 181
+P S + S+ S TP++ TQ++ + S + E ++ ++
Sbjct: 2049 MPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSAT---------AEGSSMTISAPSE 2099
Query: 182 GVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQV 241
G P+ ++PL TT + A P ++ P V + +V S P+P G +Q
Sbjct: 2100 GSPLLTSIPLSTTPVASPEASTLSTTPVDSNSP--VITSTEVSSS---PIPTEG-TSMQT 2153
Query: 242 ATSVPAPSPPLA-PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP 300
+T +P + PV A ++ TL + P+ S V A + P+ S P
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTL--STTPVDTSTPVTNSTEARSSPTTSEGTSMP 2211
Query: 301 APAP-------LSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPP 353
P S+PVS P+ +A + P PV T A +T P
Sbjct: 2212 TSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPT 2271
Query: 354 SVPMPTPTPSSGPPSTPTLIP-----AFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408
S TP + P + TL+ + TPV + TP T A +P P A ++PTS
Sbjct: 2272 STLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTS 2331
Query: 409 APIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPT 468
+ L+R+ + + LS P TP Y S ++PT
Sbjct: 2332 TSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP--VTTYSQAGSSPTTADDTSMPT 2389
Query: 469 TLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPC 528
+ + L +P V P + S S TS S E + P
Sbjct: 2390 STYSEGSTPLTSVP----------VSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPT 2439
Query: 529 TSPSGSTTTQPAPDGVPG----PLADTSLVTASAKVL-----PTPQPLLPAPSGSSAPPH 579
T+ S T P +G P++ T +V++ A L T P+ + SS+P
Sbjct: 2440 TAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTT 2499
Query: 580 PAKMPSGTEQQTEG-TSVTFSPLKSPPQLERE---MASPPECSEMPLDL-----SSKSNR 630
+ +EG T +T P+ + P E +++ P S P+ SS ++
Sbjct: 2500 AEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSA 2559
Query: 631 QKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIF 690
+ +P + L + S+K L S+ S T VT+ ++SSP
Sbjct: 2560 EGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK 2619
Query: 691 PEIVRNGDPSTWVKNSTA-LISTIP 714
+ PS + T+ L+ST+P
Sbjct: 2620 DTSMPISTPSEVSTSLTSILVSTMP 2644
Score = 90.9 bits (224), Expect = 1e-17
Identities = 165/713 (23%), Positives = 263/713 (36%), Gaps = 93/713 (13%)
Query: 108 AEGFLVPLSSPGDGL----KLPASDSAEASNSRADCSWTPLNTQ--MSKQVDCSPAGVKA 161
AEG +P S P +G +P S + S+ S TP++T M+ + S + A
Sbjct: 2441 AEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTA 2500
Query: 162 LDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPA-PICPPAPGSASVPHSVPDA 220
D + + +TL T +PV T P+ + S L P+ +P S S
Sbjct: 2501 EDIVVPISTASEG--STLLTSIPVS-TTPVASPEASTLSTTPVDSNSPVVTSTEISSSAT 2557
Query: 221 FQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLA----------PVPALAPAPPSV----- 265
S+P G P++ S+P + PLA PV P S
Sbjct: 2558 SAEGTSMPTSTYSEGSTPLR---SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSS 2614
Query: 266 PTLISD-----SNPLSVSASVL------VPVPAS-APPSGPVPLSAPAPAPLSVPVSAPP 313
PT D S P VS S+ +PV +S A P+ S S+ P
Sbjct: 2615 PTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSP 2674
Query: 314 LALIQAPVPPSAPTLVLAP-----VPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPS 368
+ +P S P P V T +LA AST P S P+ T +S P+
Sbjct: 2675 TTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734
Query: 369 TPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSA---PIPASFSLSRVCFPAA 425
T TP TP + P+ ++ + + T+A IP + S P
Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTT 2794
Query: 426 QAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSC-GQPLSVATLPTTLGVSSTLTLPVLPSY 484
+ T LT S P+ + P S LS + T+ V+++ P+
Sbjct: 2795 AEVTSMPTSTPSETSTPLT-SMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTT 2853
Query: 485 LQDRCLP--------GVLASPELRSYPYAFSVARPLTS---------------DSKLVSL 521
+ +P +L S + + P A S A L++ S +
Sbjct: 2854 AEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTA 2913
Query: 522 EVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP--PH 579
E +P ++PS +T + P+A + T S + T P+ + SS+P
Sbjct: 2914 EGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAE 2973
Query: 580 PAKMPSGT--EQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQ------ 631
MP T E++T TS++ S + ++ P + P+ S++++
Sbjct: 2974 GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEG 3033
Query: 632 ---KLPLPNQRKTP--PMPV-LTPVHTSSKALLST--VLSRSQRTTQAAGGNVTSCLGST 683
+ P++ TP +PV TPV + LST V S S T + + T
Sbjct: 3034 TGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGT 3093
Query: 684 SSPFVIFPE--IVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDP 734
S P + E G P + +++ IST+ T V + PV S + P
Sbjct: 3094 SMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSP 3146
Score = 88.6 bits (218), Expect = 5e-17
Identities = 176/791 (22%), Positives = 281/791 (35%), Gaps = 129/791 (16%)
Query: 53 VSSSFSKVELTAVGSGSNARGADP-----------DGSATEKLGHKSEDKPDDPQPKMDY 101
VSSS + E T++ + + G P SA L D +
Sbjct: 1668 VSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEA 1727
Query: 102 AGNVAEAEGFLVPLSSPGDGL----KLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPA 157
+ +EG +P S+P +G +P S + S+ + S TP++T S V S
Sbjct: 1728 RSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDT--STPVTTSTE 1785
Query: 158 GVKALDSRQGVGEKNTFILATLG--TGVPVEGTLPLVT--TNFSPLPAPICPPAPGSASV 213
+ + +G + + + T PV TL + + S P P S +V
Sbjct: 1786 ATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAV 1845
Query: 214 PHSVPDAFQVPLSVPAPVPHSGL---VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLIS 270
S A ++ P S +PV T + + L+ PA+ P + +S
Sbjct: 1846 SSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVS 1905
Query: 271 DSNPLSVSASVLVPVPASA-PPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP-----S 324
S + +S+ P PP +P+S A + + LA + PV S
Sbjct: 1906 SSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASS 1965
Query: 325 APT------------------LVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
+PT L P+ T ++ AST P S P T T S
Sbjct: 1966 SPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSS 2025
Query: 367 PST------PTLIPAFAPTP---VPAPTPAPIF----TPAPTPMPAATPAAIPT--SAPI 411
P+T T P+ TP +P T + T + TP+ + T T S+
Sbjct: 2026 PTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSA 2085
Query: 412 PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVAT------ 465
A S + P+ +P + +PLS P V +P + P P+ +T
Sbjct: 2086 TAEGSSMTISAPSEGSPLLTSIPLSTTP--VASPEASTLSTTPVDSNSPVITSTEVSSSP 2143
Query: 466 LPTTLGVSSTLT----------LPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
+PT T T +PV + + + + +P S P V +
Sbjct: 2144 IPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTP----VTNSTEAR 2199
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS 575
S + E +P ++PS +T + P+ + T SA + T P+ + +S
Sbjct: 2200 SSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTSTEATS 2259
Query: 576 APPHPAKMPSGTEQQTEGT-------------------SVTFSPLKS--PPQLEREMASP 614
+P T +EGT +++ +P+ S P E +SP
Sbjct: 2260 SPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSP 2319
Query: 615 PECSE---MPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTS-SKALLSTVLSRSQR--T 668
P +E MP SS+ N PL MPV T + S + LST + + T
Sbjct: 2320 PPTAEGTSMPTSTSSEGN---TPLTR------MPVSTTMVASFETSTLSTTPADTSTPVT 2370
Query: 669 TQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALI-----STIPGTYVGVANP 723
T + G+ + TS P + E P T V ST + ST T V + P
Sbjct: 2371 TYSQAGSSPTTADDTSMPTSTYSE---GSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTP 2427
Query: 724 VPASLLLNKDP 734
V S + P
Sbjct: 2428 VTTSTEASSSP 2438
Score = 87.0 bits (214), Expect = 1e-16
Identities = 167/741 (22%), Positives = 282/741 (38%), Gaps = 102/741 (13%)
Query: 53 VSSSFSKVELTAVGSGSNARGADPDGS--------ATEKLGHKSEDKPDDPQP---KMDY 101
VSSS + E T++ + + + G P S A+ + S D+ P +
Sbjct: 1315 VSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEA 1374
Query: 102 AGNVAEAEGFLVPLSSPGDGL----KLPASDSAEASNSRADCSWTPLNTQM----SKQVD 153
+ +EG +P S+P +G +P S + S+ + S TP++T S +
Sbjct: 1375 CSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEAT 1434
Query: 154 CSPA---GVKALDSRQGVGE--------KNTFIL----ATLGTGVPVEGTLPLVTT---N 195
SP G+ S G+ NT + +TL T PV+ P+VT+ +
Sbjct: 1435 SSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLST-TPVDSNSPVVTSTAVS 1493
Query: 196 FSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPV 255
SP PA S+ S P L+ PV + + ++ + P+ PV
Sbjct: 1494 SSPTPAE-------GTSIAISTPSEGSTALT-SIPVSTTTVASSEINSLSTTPAVTSTPV 1545
Query: 256 PALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA------PAPLSVPV 309
+ A S T S S + P+ S P S + +S+ A P V
Sbjct: 1546 TTYSQASSSPTTADGTSMQTSTYSEGSTPL-TSLPVSTMLVVSSEANTLSTTPIDSKTQV 1604
Query: 310 SAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPST 369
+A A S+ T+ +P+L +P ST P A S TP S+ P T
Sbjct: 1605 TASTEASSSTTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVIT 1664
Query: 370 PTLIPAFAPTPVPAPT-PAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV--CFPAAQ 426
T + + +PTP + P +T TP+ + T P ++ ++ S + V P
Sbjct: 1665 STEVSS-SPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTT 1723
Query: 427 APAMQKVPLSFQPGTVL---TPSQ---PLVYIPP------PSCGQPLSVATLPTTLGVSS 474
+ + P + + GT + TPS+ PL IP S LS + T+ V++
Sbjct: 1724 STEARSSPTTSE-GTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTT 1782
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
+ P+ + +P S + + V+ L ++S+ +L + SP
Sbjct: 1783 STEATSSPTTAEGTSIPTSTLSEGMTPLT-STPVSHTLVANSEASTLSTTPVDSNSP--- 1838
Query: 535 TTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGT 594
T A P P TS+ T++ P+ ++ P + +T
Sbjct: 1839 VVTSTAVSSSPTPAEGTSIATST-----------PSEGSTALTSIPVSTTTVASSETNTL 1887
Query: 595 SVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSS 654
S T + +P +++S P ++ +S + PL + +PV T SS
Sbjct: 1888 STTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTS------IPVSTTTVASS 1941
Query: 655 KA-LLSTVL--SRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALI- 710
+ LST L +R+ TT + + + TS P + E P T + ST L+
Sbjct: 1942 EINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAYSE---GSTPLTSMPLSTTLVV 1998
Query: 711 ----STIPGTYVGVANPVPAS 727
ST+ T V + P S
Sbjct: 1999 SSEASTLSTTPVDTSTPATTS 2019
Score = 81.3 bits (199), Expect = 8e-15
Identities = 162/733 (22%), Positives = 265/733 (36%), Gaps = 122/733 (16%)
Query: 109 EGFLVPLSSPGDG----LKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDS 164
E +P S+ +G +PAS AS+ TP+ ++S V S + +
Sbjct: 202 ESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTPV--EISTPVTISAQASSSPTT 259
Query: 165 RQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVP 224
+G +L P G+ PL +P + AS + P A +P
Sbjct: 260 AEG---------PSLSNSAPSGGSTPLTR-----MPLSVMLVVSSEASTLSTTPAATNIP 305
Query: 225 LSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVP 284
+ S TS+P + P + ++P S+ + LS++ P
Sbjct: 306 VITSTEASSSPTTAE--GTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSIT-----P 358
Query: 285 VPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPAS 344
V S L + P S+P +A +++ + + + L PV T ++A AS
Sbjct: 359 VDTST-------LVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEAS 411
Query: 345 TPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAA 404
T P + T + +S P+T TP TP + TP+ A++ A+
Sbjct: 412 TTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPV-ASSEAS 470
Query: 405 IPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVA 464
++ P+ + ++ A+ +P +V S T S PL +SV+
Sbjct: 471 NLSTTPVDSKTQVT-TSTEASSSPPTAEVN-SMPTSTPSEGSTPLT---------SMSVS 519
Query: 465 TLPTTLGVSSTL-TLPVLPSYLQDRCLPGVLAS--------PELRSYPYAFSVARPLTSD 515
T+P +STL T PV D P +S PE S P + P
Sbjct: 520 TMPVASSEASTLSTTPV------DTSTPVTTSSEASSSSTTPEGTSIP----TSTPSEGS 569
Query: 516 SKLVSLEVN-RLPCTSPSGSTTTQPAPDG---VPGPLADTSLVTASAKVLPTP------- 564
+ L ++ V+ RL +S + +T+T PA A +S TA +PT
Sbjct: 570 TPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGT 629
Query: 565 -------QPLLPAPSGS---SAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASP 614
L A S + S P + P T + +S T P E ++P
Sbjct: 630 TITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTP 689
Query: 615 PECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGG 674
+ MP++ + ++ + L T P+ TPV TS++A S TT
Sbjct: 690 --LTSMPVNTTLVASSEASTL----STTPVDTSTPVTTSTEA-------SSSPTTADGAS 736
Query: 675 NVTSCLGSTSSPFVIFP---EIVRNG----------DPSTWVKNSTALI---STIPGTYV 718
TS S+P P ++ + D ST + ST +T GT +
Sbjct: 737 MPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSM 796
Query: 719 GVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISI--IDQGEPKGTGATCGKKGSQAGAE 776
++ P S LL P ++ P P+ +S +D P T S AE
Sbjct: 797 PISTPSEGSPLLTSIP---VSITPVTSPEASTLSTTPVDSNSPVTTSTEV--SSSPTPAE 851
Query: 777 GQPSTVKRYTPAR 789
G Y+ R
Sbjct: 852 GTSMPTSTYSEGR 864
Score = 75.9 bits (185), Expect = 3e-13
Identities = 155/684 (22%), Positives = 256/684 (37%), Gaps = 128/684 (18%)
Query: 108 AEGFLVPLSSPGDG----LKLPASDSAEASNSRADCSWTPLNTQM----SKQVDCSPAGV 159
AE +P S+ G+G +P S + AS+ + S TP+++ S Q SPA +
Sbjct: 3502 AEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTSSSQASSSPATL 3561
Query: 160 KALDSR-----QGVGEKNTFIL---------ATLGTGVPVEGTLPLVT-TNFSPLPAPIC 204
+ R +G T +L A+ + V+ + P+ T T + P P
Sbjct: 3562 QVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTPVTTSTQSNSTPTP-- 3619
Query: 205 PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL----------VPVQ----VATSVPAPSP 250
P ++P S P PL++ PV + + +PV V TS S
Sbjct: 3620 ---PEVITLPMSTPSEVSTPLTI-MPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSS 3675
Query: 251 PLAP----VPALAPAPPSVP--TLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAP 304
P+ P +P P+ S P T+ + ++ S + P S S PV S A +
Sbjct: 3676 PVTPEGTTMPIWTPSEGSTPLTTMPVSTTRVTSSEGSTLSTP-SVVTSTPVTTSTEAISS 3734
Query: 305 LSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSS 364
+ S + + T++++ TPV +STP S+ M T + S
Sbjct: 3735 SATLDSTTMSVSMPMEISTLGTTILVST--TPVTRFPESSTPSIPSVYTSMSMTTASEGS 3792
Query: 365 GPPST---------------PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSA 409
P+T TL+ +P+ +P+ T + P +TP T A
Sbjct: 3793 SSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLSTPPGDTSTPLLTSTKA 3852
Query: 410 ---PIPASFSLSRVCFPAAQAPAM------QKVPLSFQPGTVLTPSQPLVYIPPPSCGQP 460
IPA + R+ + ++ + +P SF PG + + PL
Sbjct: 3853 GSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSF-PGASIASTPPL----------D 3901
Query: 461 LSVATLPTTLGVSSTLTLPVLP----SYLQDRCLPG----VLASPELRSYPYAFSVARPL 512
S P+T +ST T+PV S + + PG + ++P S F
Sbjct: 3902 TSTTFTPST-DTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGA 3960
Query: 513 TSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPS 572
S + S E+N P TS S +TT+ + T T A P L +
Sbjct: 3961 VSTPVITSTELN-TPSTSSSSTTTS----------FSTTKEFTTPAMTTAAP---LTYVT 4006
Query: 573 GSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQK 632
S+AP P G S T +P S R + +P S P ++S +
Sbjct: 4007 MSTAPSTPRTTSRGCTTSASTLSATSTPHTSTSVTTRPV-TPSSESSRPSTITSHTIPPT 4065
Query: 633 LPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPE 692
P P TPP + + +A ++T+ +R++ +T+ +TS P V
Sbjct: 4066 FP-PAHSSTPPTTSASSTTVNPEA-VTTMTTRTKPSTR-----------TTSFPTVTTTA 4112
Query: 693 IVRNGDPSTWVKNSTALISTIPGT 716
+ N T +K++ T+P T
Sbjct: 4113 VPTN----TTIKSNPTSTPTVPRT 4132
Score = 57.8 bits (138), Expect = 9e-08
Identities = 167/785 (21%), Positives = 275/785 (35%), Gaps = 90/785 (11%)
Query: 291 PSGPVPLSAPA-PAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAA 349
PS S+P P VP+S P I + +A V T L A T
Sbjct: 130 PSSTEDTSSPTTPEGTDVPMSTPSEESISS---------TMAFVSTAPLPSFEAYTSLTY 180
Query: 350 PAPPSVPMPTPTPSSGPPSTP--TLIP-------AFAPTPVPAPT----PAPIFTPAPTP 396
S P+ T T +S P+TP T IP + T +PA T + T TP
Sbjct: 181 KVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEGSTPLTSMPASTMKVASSEAITLLTTP 240
Query: 397 MPAATPAAI---PTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP 453
+ +TP I +S+P A P+ + + ++PLS V++ +
Sbjct: 241 VEISTPVTISAQASSSPTTAEGPSLSNSAPSGGSTPLTRMPLSVM--LVVSSEASTLSTT 298
Query: 454 PPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRC-LPGVLAS--PELRSYPYAFSVAR 510
P + P+ +T ++ ++ T +Y + L AS P S S+
Sbjct: 299 PAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITP 358
Query: 511 PLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLAD----TSLVTASAKVLPTPQP 566
TS S E + LP T+ + S T +G PL + T LV +S + P
Sbjct: 359 VDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEG-STPLTNMPVSTILVASSEASTTSTIP 417
Query: 567 ------LLPAPSGSSAPPHPAKMPSGTEQQTEG-TSVTFSPLKSPPQLEREMASPPECSE 619
+ A SS+P T +EG T +T P+ + P E ++ S
Sbjct: 418 VDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASN---LST 474
Query: 620 MPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSC 679
P+D S Q +PP + + TS+ + ST L+ +T + S
Sbjct: 475 TPVD----SKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEAST 530
Query: 680 LGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLN 739
L +T V P T +++ +T GT + + P S L P
Sbjct: 531 LSTTP---------VDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMP----- 576
Query: 740 RDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQT 799
R + E + T T + S + + +++ T + + +
Sbjct: 577 VSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITS-MS 635
Query: 800 KELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAP 859
+L + + + + P +T S + + + + G TP P
Sbjct: 636 VSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGS-TPLTSMP 694
Query: 860 IRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQV 919
+ T V S S +LS++ P S P T + + P E
Sbjct: 695 VNTTLVAS--SEASTLSTTPVDTSTPVTTSTEASS-----SPTTADGASMPTSTPSE--- 744
Query: 920 NPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGD 979
LT P + TL S + S ++ P ++ +H+ + ST P G +
Sbjct: 745 GSTPLTSMPVSKTLLTSSEAS----TLSTTPLDTSTHI-TTSTEASCSPTTTEGTSMPIS 799
Query: 980 TKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQ 1039
T + L T + V TP P+ L P DS+ V +S SS+ P
Sbjct: 800 TPSEGSPLLTSIP---VSITPVTSPEASTLSTTPVDSN------SPVTTSTEVSSSPTPA 850
Query: 1040 LGSQV 1044
G+ +
Sbjct: 851 EGTSM 855
Score = 53.5 bits (127), Expect = 2e-06
Identities = 115/559 (20%), Positives = 199/559 (35%), Gaps = 82/559 (14%)
Query: 326 PTLVLAPVPTPVLAPMPASTPPAAPAPPSV---PMPTPTPSSGPPSTPTLIPAFAPTPVP 382
P + L+ P + + +S P S P + T S + TL P+
Sbjct: 79 PRMYLSCSTNPEMTSIESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSS 138
Query: 383 APTPAPIFTPAPTPM--PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPG 440
TP P TP ++ A ++AP+P+ + + + + + PL+
Sbjct: 139 PTTPEGTDVPMSTPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMS-----TPLTTSTQ 193
Query: 441 TVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR 500
+P+ P P S S + P T +ST+ V +S +
Sbjct: 194 ASSSPTTPESTTIPKSTN---SEGSTPLTSMPASTMK---------------VASSEAIT 235
Query: 501 SYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSL-----VT 555
++ P+T +S + + P T+ G + + AP G PL L V+
Sbjct: 236 LLTTPVEISTPVT-----ISAQASSSP-TTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVS 289
Query: 556 ASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPP 615
+ A L T P+ ++ P + S + EGTS+ P + + + S P
Sbjct: 290 SEASTLST------TPAATNIPVITSTEASSSPTTAEGTSI---PTSTYTEGSTPLTSTP 340
Query: 616 ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGN 675
S MP+ S S +TPV TS+ ST S S TT A
Sbjct: 341 -ASTMPVATSEMSTLS---------------ITPVDTSTLVTTSTEPS-SLPTTAEATSM 383
Query: 676 VTSCLGSTSSPFVIFPE---IVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNK 732
+TS L S+P P +V + + ST T+ I T+V A+ +S +
Sbjct: 384 LTSTLSEGSTPLTNMPVSTILVASSEAST-----TSTIPVDSKTFVTTASEASSSPTTAE 438
Query: 733 DPNLGLNRDPRHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAP 792
D ++ + P + + P T + S S + T +
Sbjct: 439 DTSIATS-----TPSEGSTPLTSM--PVSTTPVASSEASNLSTTPVDSKTQVTTSTEASS 491
Query: 793 GLPGCQTKELSLWKPTGPANIYPRCSVNGKP-TSTQVLPVGWSPYHQASLLSIGISSAGQ 851
P + + P+ + SV+ P S++ + +P ++ ++ ++
Sbjct: 492 SPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSS 551
Query: 852 LTPSQGAPIRPTSVVSEFS 870
T +G I PTS SE S
Sbjct: 552 STTPEGTSI-PTSTPSEGS 569
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 114 bits (285), Expect = 8e-25
Identities = 78/248 (31%), Positives = 105/248 (42%), Gaps = 16/248 (6%)
Query: 184 PVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVAT 243
P+ G++P + +P+PI P PG S P +P F+ P+ P P SG P+
Sbjct: 112 PLPGSIPGPIPGPAQIPSPIPAPIPGPISGPVQIPGPFRGPI----PGPISGPAPIPGPI 167
Query: 244 SVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV--PLSAPA 301
S P P P+P P P P S P+ SV +P P P SGP+ P P
Sbjct: 168 SGPFSGPNPGPIPGPNPGPIPGPI----SGPIPGPISVPIPGPIPGPISGPISGPNPGPI 223
Query: 302 PAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAP----MPASTPPAAPAPPSVPM 357
P P+ P+S P I P+ P L+ P+P P+ P P +P P P +
Sbjct: 224 PGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQG 283
Query: 358 PTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIP--TSAPIPASF 415
P P S G +P +P AP P P PAP P P + PA P +P + F
Sbjct: 284 PGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPLWPQSPDASDF 343
Query: 416 SLSRVCFP 423
FP
Sbjct: 344 LPDTQLFP 351
Score = 114 bits (284), Expect = 1e-24
Identities = 94/298 (31%), Positives = 125/298 (41%), Gaps = 47/298 (15%)
Query: 197 SPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSP-PLA-- 253
SP P PI P PG A +P +P S+P P+P P Q+ + +PAP P P++
Sbjct: 93 SPGPGPIPAPIPGPAQIPGPLPG------SIPGPIPG----PAQIPSPIPAPIPGPISGP 142
Query: 254 ---PVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV--PLSAPAPAPLSVP 308
P P P P + P+S S P P P GP+ P+S P P P+SVP
Sbjct: 143 VQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGPIPGPISVP 202
Query: 309 VSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPP--AAPAPPSVPMPTPTPSSGP 366
+ P I P+ P + P+P P+ P P P + P P +P P P P SGP
Sbjct: 203 IPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGP 262
Query: 367 PSTPTLIPAFAPTPVPAP----TPAPIFTP------------APTPMPAATPAAIPTSAP 410
P + P +P +P P P PI +P AP P + P + AP
Sbjct: 263 --GPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAP 320
Query: 411 IPASFSLSRVCFPAAQAPAMQKVP--LSFQPGTVLTPSQPLVYIP-PPSCGQPLSVAT 465
IP SL A AP + P F P T L P + +P P G +S T
Sbjct: 321 IPGPGSL------PAPAPLWPQSPDASDFLPDTQLFPHFTELLLPLDPLEGSSVSTMT 372
Score = 62.4 bits (150), Expect = 4e-09
Identities = 59/196 (30%), Positives = 73/196 (37%), Gaps = 41/196 (20%)
Query: 183 VPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVA 242
VP+ G +P P+ PI P PG P+ P P P SG P
Sbjct: 201 VPIPGPIP------GPISGPISGPNPG--------------PIPGPIPGPISGPNP---- 236
Query: 243 TSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAP-- 300
P P P P P L P P +P P+S ++ P+P+ A GP L P
Sbjct: 237 --GPIPGPISGPNPGLIPGP--IP------GPISGPGPIIGPIPSPAQIPGPGRLQGPGP 286
Query: 301 --APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP 358
+P + P S P LA I P V AP+P P P PA P P P
Sbjct: 287 ILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPA---PLWPQSPDASDF 343
Query: 359 TPTPSSGPPSTPTLIP 374
P P T L+P
Sbjct: 344 LPDTQLFPHFTELLLP 359
Score = 56.2 bits (134), Expect = 3e-07
Identities = 74/298 (24%), Positives = 98/298 (32%), Gaps = 65/298 (21%)
Query: 310 SAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPST 369
+AP + A P P+ +L + + A P A +P +P GP
Sbjct: 43 AAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQKGIPAAL-SPGPGP--- 98
Query: 370 PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPA 429
IPA P P P P P P P P PA P+ IP APIP S Q P
Sbjct: 99 ---IPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIP--APIPGPIS------GPVQIPG 147
Query: 430 MQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRC 489
+ P+ PG + P+ IP P G P S G +
Sbjct: 148 PFRGPI---PGPISGPAP----IPGPISG-PFSGPNPGPIPGPN---------------- 183
Query: 490 LPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLA 549
PG + P P SV P P + P P P +PGP++
Sbjct: 184 -PGPIPGPISGPIPGPISVPIPGPIPG----------PISGPISGPNPGPIPGPIPGPIS 232
Query: 550 DTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQL 607
P P P+ SG P+P +P G P+ SP Q+
Sbjct: 233 G-----------PNPGPIPGPISG----PNPGLIPGPIPGPISGPGPIIGPIPSPAQI 275
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 111 bits (278), Expect = 5e-24
Identities = 129/527 (24%), Positives = 187/527 (35%), Gaps = 39/527 (7%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P TT P P PAP + P P + P P + P T P+P+
Sbjct: 325 PTPTTPKEPAPTTK-EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVP-VPASAPPSGPVPLSAPAPAPLSVP 308
P P P S PT + P + ++ P P+ P P + PAP +
Sbjct: 384 TPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440
Query: 309 VSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
AP AP P APT P PT P P + AP P PT TP
Sbjct: 441 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLA 499
Query: 367 PST-----PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT------PAAIPTSAPIPASF 415
P+T PT APT PTP PAPT AA PA P P +
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 416 SLSRVCFPAAQAPAMQK--VPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVS 473
P AP K P + + TP +P P+ + + T +
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 474 STLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSG 533
T P P + + P P T+ K E+ P+
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAPKELAPTTTKGPTS 678
Query: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEG 593
+T+ +PAP P A T+ + PT P PAP+ PP S E
Sbjct: 679 TTSDKPAPT-TPKETAPTT----PKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEP 732
Query: 594 TSVTFSPLKSPPQLERE-----MASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT 648
T++ SP +S P+L E + + P+ +P + + + ++ + KT + T
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 792
Query: 649 PVHTSSKA--LLSTVLSRSQRTTQ----AAGGNVTSCLGSTSSPFVI 689
T++ A + + +++TT+ A VTS ++PF I
Sbjct: 793 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 839
Score = 108 bits (271), Expect = 3e-23
Identities = 145/624 (23%), Positives = 205/624 (32%), Gaps = 89/624 (14%)
Query: 178 TLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV 237
T P P TT P P PAP + P P + P P +
Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 238 PVQVATSVPAPSPP------------------LAPVPALAPAPPS----VPTLISDSNPL 275
P PAP+ P LAP PAP + PT + P
Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525
Query: 276 SVSASVLVPVPASAP--PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP--SAPTLVLA 331
+ A+AP P P P + PAP + AP AP P +APT +
Sbjct: 526 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 585
Query: 332 PVPTPVLAPMP---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT--- 385
P PT P P A T P + P PT G T PA PAPT
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645
Query: 386 ---PAPIFTPAP-TPMPAATPAAIPTSAPIPASFSLSRVC--FPAAQAPAMQKVPLSFQP 439
P + PAP TP A PT+ P S + + P AP K P P
Sbjct: 646 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP---AP 702
Query: 440 GTVLTPSQPLVYIPPPSCGQPLSVATL--PTTLGVSSTLTLPVLPSYLQDRCL------P 491
T P+ PPP+ + + T PTT+ S + P L + + L P
Sbjct: 703 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Query: 492 GV-------LASPE-------------LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSP 531
GV PE LR+ P + A +T ++ + + T+
Sbjct: 763 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 822
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
+ T+ D P + T + KV T + + + P AK
Sbjct: 823 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI-MNKPEETAKPKDRATNSK 881
Query: 592 EGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVH 651
T P K+P + P ++ P + + P P ++ T MP L P
Sbjct: 882 ATTPKPQKPTKAPKK--------PTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 932
Query: 652 TSSKALLSTVLSRSQR----------TTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
++A+L T +Q ++ AGG P V PE+ + D
Sbjct: 933 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 992
Query: 702 WVKNSTALISTIPGTYVGVANPVP 725
V N +I+ + + N P
Sbjct: 993 RVPNQGIIINPMLSDETNICNGKP 1016
Score = 102 bits (255), Expect = 2e-21
Identities = 137/553 (24%), Positives = 179/553 (32%), Gaps = 69/553 (12%)
Query: 200 PAPICPPAPGSAS----VPHSVPDAFQVPLSVPAPV-----PHSGLVPVQVATSVPAPSP 250
P P P P S + P ++ A P PAP P + P T PAP+
Sbjct: 216 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTTKEPAPTT 274
Query: 251 PLAPVPALA--PAPP---SVPTLISDSNPLSVS--ASVLVPVPASAPPSGPVPLSAPAPA 303
P P P PAP S PT + P + A PA P P P + PA
Sbjct: 275 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 334
Query: 304 PLSVPVSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPT-- 359
P + AP AP P APT P PT P P +T +P P P PT
Sbjct: 335 P-TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 393
Query: 360 -----------PTPSSGPPSTP-------TLIPAFA----PTPVPAPTPAPIFTPAPTPM 397
PT + P+TP T PA P P PAP P P
Sbjct: 394 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453
Query: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP-PPS 456
PA T P P + P AP K P LTP+ P P P
Sbjct: 454 TPKEPAPTTTKKPAPTT--------PKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPE 504
Query: 457 CGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPL-TSD 515
P + L T T T P P+ + A+P P + P T+
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA-----AAPNTPKEPAPTTPKEPAPTTP 559
Query: 516 SKLVSLEVNRLPCTSPSGSTTT---QPAP----DGVPGPLADTSLVTASAKVLPTPQPLL 568
+ T+P G+ T +PAP P LA T+ ++ P P
Sbjct: 560 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 619
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
P + + P PA T + LK P + +P E + + +
Sbjct: 620 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679
Query: 629 NRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGST--SSP 686
K ++T P P T+ K T TT T+ +T SP
Sbjct: 680 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 739
Query: 687 FVIFPEIVRNGDP 699
PE+ P
Sbjct: 740 DESTPELSAEPTP 752
Score = 94.4 bits (233), Expect = 9e-19
Identities = 139/555 (25%), Positives = 181/555 (32%), Gaps = 73/555 (13%)
Query: 286 PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPT-LVLAPVPTPVLAPMPAS 344
PA P P P + PA + P P + AP P P PT P P +
Sbjct: 208 PALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266
Query: 345 TPPAAPAPPSVPMPTPTPSSGPPST---PTLIPAFAPT--PVPAPT----PAPIFTPAPT 395
T AP P P PT T P +T PT APT PAPT PAP PT
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 326
Query: 396 PMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
P PA T P P + P AP K P P T P+ P P
Sbjct: 327 PTTPKEPAP-TTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTKEPSP 382
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
+ + PTT + T T P+ + SP P + P +
Sbjct: 383 TTPK----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 438
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS 575
K P+ +T +PAP P T+ A TP+ P +
Sbjct: 439 PK------------KPAPTTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKET 482
Query: 576 APPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPL 635
AP P K+ T ++ T +P K P E+A P E P + + P
Sbjct: 483 APTTPKKLTPTTPEKLAPT----TPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 536
Query: 636 PNQRKTPPMPVLT----PVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFP 691
TP P T P T+ K T + TT T + ++P P
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 692 EIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPI 751
+ + +T ST P T G A P ++P +EP
Sbjct: 597 KEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTP--------------KEPAPTTPKEPA 640
Query: 752 SIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELS-LWKPTGP 810
PKGT T K E P+T K+ P +AP T S PT P
Sbjct: 641 PT----TPKGTAPTTLK-------EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689
Query: 811 ANIYPRCSVNGKPTS 825
P PT+
Sbjct: 690 KETAPTTPKEPAPTT 704
Score = 90.5 bits (223), Expect = 1e-17
Identities = 161/669 (24%), Positives = 222/669 (33%), Gaps = 101/669 (15%)
Query: 311 APPLALIQAPVPPS-----APTLVLAPVPTPVLAPMPASTPPAAPAP------PSVPM-P 358
AP ++ P P + P L PTP PAST P P P P+ P P
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPT----PAPIFTPAPTPMPAATPAAIPTSAPIPAS 414
PT + P+TP PA T PAPT PAP T P P T + PT+ PA
Sbjct: 248 APTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTPKEPAP 303
Query: 415 FSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
+ P AP K P P T P+ P P+ +P PTT
Sbjct: 304 TT------PKKPAPTTPKEP---APTTPKEPTPTTPKEPAPTTKEP-----APTT-PKEP 348
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
T P P+ P P P P T+ + P T+ S
Sbjct: 349 APTAPKKPA-------PTTPKEPA----PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397
Query: 535 TTTQPAPDGVPGPLADTSLVTASAKVLPT----PQPLLPAPSGSSAPPHPA----KMPSG 586
TTT+ P P S T + PT P P P + P PA K P+
Sbjct: 398 TTTKE-----PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPV 646
T + + T P + P+ E +P E ++ + +KL K P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPK-EPAPTTPKE--------TAPTTPKKLTPTTPEKLAPTTP 503
Query: 647 LTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS 706
P T+ + L T TT T + ++P P + P+T + +
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 707 -TALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGAT 765
T T P T G A P +L K+P P K P + + T T
Sbjct: 564 PTTPKETAPTTPKGTA---PTTL---KEP------APTTPKKPAPKELAPTTTKEPTSTT 611
Query: 766 CGKKGSQAGAEGQPSTVKR---YTPARIAPGLP-GCQTKELSLWKPTGPANIYPR----C 817
C K P+T K TP AP P G L PT P P+
Sbjct: 612 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671
Query: 818 SVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSS 877
+ G ++T P +P A + P+ P P SE S +
Sbjct: 672 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731
Query: 878 SEAVHGLPE-------GQPRPGGSFVPEQDPVTKNKTCRIAAKP-----YEEQVNPVLLT 925
+H P+ +P P ++P A KP +++ L
Sbjct: 732 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 791
Query: 926 LSPQTGTLA 934
+P+T T A
Sbjct: 792 TTPETTTAA 800
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 111 bits (278), Expect = 5e-24
Identities = 129/527 (24%), Positives = 187/527 (35%), Gaps = 39/527 (7%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P TT P P PAP + P P + P P + P T P+P+
Sbjct: 366 PTPTTPKEPAPTTK-EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVP-VPASAPPSGPVPLSAPAPAPLSVP 308
P P P S PT + P + ++ P P+ P P + PAP +
Sbjct: 425 TPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481
Query: 309 VSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
AP AP P APT P PT P P + AP P PT TP
Sbjct: 482 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLA 540
Query: 367 PST-----PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT------PAAIPTSAPIPASF 415
P+T PT APT PTP PAPT AA PA P P +
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 416 SLSRVCFPAAQAPAMQK--VPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVS 473
P AP K P + + TP +P P+ + + T +
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 474 STLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSG 533
T P P + + P P T+ K E+ P+
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAPKELAPTTTKGPTS 719
Query: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEG 593
+T+ +PAP P A T+ + PT P PAP+ PP S E
Sbjct: 720 TTSDKPAPT-TPKETAPTT----PKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEP 773
Query: 594 TSVTFSPLKSPPQLERE-----MASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT 648
T++ SP +S P+L E + + P+ +P + + + ++ + KT + T
Sbjct: 774 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 833
Query: 649 PVHTSSKA--LLSTVLSRSQRTTQ----AAGGNVTSCLGSTSSPFVI 689
T++ A + + +++TT+ A VTS ++PF I
Sbjct: 834 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 880
Score = 108 bits (271), Expect = 3e-23
Identities = 145/624 (23%), Positives = 205/624 (32%), Gaps = 89/624 (14%)
Query: 178 TLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV 237
T P P TT P P PAP + P P + P P +
Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 238 PVQVATSVPAPSPP------------------LAPVPALAPAPPS----VPTLISDSNPL 275
P PAP+ P LAP PAP + PT + P
Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566
Query: 276 SVSASVLVPVPASAP--PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP--SAPTLVLA 331
+ A+AP P P P + PAP + AP AP P +APT +
Sbjct: 567 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 626
Query: 332 PVPTPVLAPMP---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT--- 385
P PT P P A T P + P PT G T PA PAPT
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686
Query: 386 ---PAPIFTPAP-TPMPAATPAAIPTSAPIPASFSLSRVC--FPAAQAPAMQKVPLSFQP 439
P + PAP TP A PT+ P S + + P AP K P P
Sbjct: 687 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP---AP 743
Query: 440 GTVLTPSQPLVYIPPPSCGQPLSVATL--PTTLGVSSTLTLPVLPSYLQDRCL------P 491
T P+ PPP+ + + T PTT+ S + P L + + L P
Sbjct: 744 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Query: 492 GV-------LASPE-------------LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSP 531
GV PE LR+ P + A +T ++ + + T+
Sbjct: 804 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 863
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
+ T+ D P + T + KV T + + + P AK
Sbjct: 864 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI-MNKPEETAKPKDRATNSK 922
Query: 592 EGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVH 651
T P K+P + P ++ P + + P P ++ T MP L P
Sbjct: 923 ATTPKPQKPTKAPKK--------PTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 973
Query: 652 TSSKALLSTVLSRSQR----------TTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
++A+L T +Q ++ AGG P V PE+ + D
Sbjct: 974 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1033
Query: 702 WVKNSTALISTIPGTYVGVANPVP 725
V N +I+ + + N P
Sbjct: 1034 RVPNQGIIINPMLSDETNICNGKP 1057
Score = 102 bits (255), Expect = 2e-21
Identities = 137/553 (24%), Positives = 179/553 (32%), Gaps = 69/553 (12%)
Query: 200 PAPICPPAPGSAS----VPHSVPDAFQVPLSVPAPV-----PHSGLVPVQVATSVPAPSP 250
P P P P S + P ++ A P PAP P + P T PAP+
Sbjct: 257 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTTKEPAPTT 315
Query: 251 PLAPVPALA--PAPP---SVPTLISDSNPLSVS--ASVLVPVPASAPPSGPVPLSAPAPA 303
P P P PAP S PT + P + A PA P P P + PA
Sbjct: 316 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 375
Query: 304 PLSVPVSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPT-- 359
P + AP AP P APT P PT P P +T +P P P PT
Sbjct: 376 P-TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 434
Query: 360 -----------PTPSSGPPSTP-------TLIPAFA----PTPVPAPTPAPIFTPAPTPM 397
PT + P+TP T PA P P PAP P P
Sbjct: 435 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494
Query: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP-PPS 456
PA T P P + P AP K P LTP+ P P P
Sbjct: 495 TPKEPAPTTTKKPAPTT--------PKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPE 545
Query: 457 CGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPL-TSD 515
P + L T T T P P+ + A+P P + P T+
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA-----AAPNTPKEPAPTTPKEPAPTTP 600
Query: 516 SKLVSLEVNRLPCTSPSGSTTT---QPAP----DGVPGPLADTSLVTASAKVLPTPQPLL 568
+ T+P G+ T +PAP P LA T+ ++ P P
Sbjct: 601 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 660
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
P + + P PA T + LK P + +P E + + +
Sbjct: 661 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720
Query: 629 NRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGST--SSP 686
K ++T P P T+ K T TT T+ +T SP
Sbjct: 721 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 780
Query: 687 FVIFPEIVRNGDP 699
PE+ P
Sbjct: 781 DESTPELSAEPTP 793
Score = 94.4 bits (233), Expect = 9e-19
Identities = 139/555 (25%), Positives = 181/555 (32%), Gaps = 73/555 (13%)
Query: 286 PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPT-LVLAPVPTPVLAPMPAS 344
PA P P P + PA + P P + AP P P PT P P +
Sbjct: 249 PALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307
Query: 345 TPPAAPAPPSVPMPTPTPSSGPPST---PTLIPAFAPT--PVPAPT----PAPIFTPAPT 395
T AP P P PT T P +T PT APT PAPT PAP PT
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 367
Query: 396 PMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
P PA T P P + P AP K P P T P+ P P
Sbjct: 368 PTTPKEPAP-TTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTKEPSP 423
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
+ + PTT + T T P+ + SP P + P +
Sbjct: 424 TTPK----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 479
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS 575
K P+ +T +PAP P T+ A TP+ P +
Sbjct: 480 PK------------KPAPTTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKET 523
Query: 576 APPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPL 635
AP P K+ T ++ T +P K P E+A P E P + + P
Sbjct: 524 APTTPKKLTPTTPEKLAPT----TPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 577
Query: 636 PNQRKTPPMPVLT----PVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFP 691
TP P T P T+ K T + TT T + ++P P
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 692 EIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPI 751
+ + +T ST P T G A P ++P +EP
Sbjct: 638 KEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTP--------------KEPAPTTPKEPA 681
Query: 752 SIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELS-LWKPTGP 810
PKGT T K E P+T K+ P +AP T S PT P
Sbjct: 682 PT----TPKGTAPTTLK-------EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730
Query: 811 ANIYPRCSVNGKPTS 825
P PT+
Sbjct: 731 KETAPTTPKEPAPTT 745
Score = 90.5 bits (223), Expect = 1e-17
Identities = 161/669 (24%), Positives = 222/669 (33%), Gaps = 101/669 (15%)
Query: 311 APPLALIQAPVPPS-----APTLVLAPVPTPVLAPMPASTPPAAPAP------PSVPM-P 358
AP ++ P P + P L PTP PAST P P P P+ P P
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPT----PAPIFTPAPTPMPAATPAAIPTSAPIPAS 414
PT + P+TP PA T PAPT PAP T P P T + PT+ PA
Sbjct: 289 APTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTPKEPAP 344
Query: 415 FSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
+ P AP K P P T P+ P P+ +P PTT
Sbjct: 345 TT------PKKPAPTTPKEP---APTTPKEPTPTTPKEPAPTTKEP-----APTT-PKEP 389
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
T P P+ P P P P T+ + P T+ S
Sbjct: 390 APTAPKKPA-------PTTPKEPA----PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438
Query: 535 TTTQPAPDGVPGPLADTSLVTASAKVLPT----PQPLLPAPSGSSAPPHPA----KMPSG 586
TTT+ P P S T + PT P P P + P PA K P+
Sbjct: 439 TTTKE-----PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPV 646
T + + T P + P+ E +P E ++ + +KL K P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPK-EPAPTTPKE--------TAPTTPKKLTPTTPEKLAPTTP 544
Query: 647 LTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS 706
P T+ + L T TT T + ++P P + P+T + +
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 707 -TALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGAT 765
T T P T G A P +L K+P P K P + + T T
Sbjct: 605 PTTPKETAPTTPKGTA---PTTL---KEP------APTTPKKPAPKELAPTTTKEPTSTT 652
Query: 766 CGKKGSQAGAEGQPSTVKR---YTPARIAPGLP-GCQTKELSLWKPTGPANIYPR----C 817
C K P+T K TP AP P G L PT P P+
Sbjct: 653 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712
Query: 818 SVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSS 877
+ G ++T P +P A + P+ P P SE S +
Sbjct: 713 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772
Query: 878 SEAVHGLPE-------GQPRPGGSFVPEQDPVTKNKTCRIAAKP-----YEEQVNPVLLT 925
+H P+ +P P ++P A KP +++ L
Sbjct: 773 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 832
Query: 926 LSPQTGTLA 934
+P+T T A
Sbjct: 833 TTPETTTAA 841
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 111 bits (278), Expect = 5e-24
Identities = 129/527 (24%), Positives = 187/527 (35%), Gaps = 39/527 (7%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P TT P P PAP + P P + P P + P T P+P+
Sbjct: 418 PTPTTPKEPAPTTK-EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 476
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVP-VPASAPPSGPVPLSAPAPAPLSVP 308
P P P S PT + P + ++ P P+ P P + PAP +
Sbjct: 477 TPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533
Query: 309 VSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
AP AP P APT P PT P P + AP P PT TP
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLA 592
Query: 367 PST-----PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT------PAAIPTSAPIPASF 415
P+T PT APT PTP PAPT AA PA P P +
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 416 SLSRVCFPAAQAPAMQK--VPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVS 473
P AP K P + + TP +P P+ + + T +
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 474 STLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSG 533
T P P + + P P T+ K E+ P+
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAPKELAPTTTKGPTS 771
Query: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEG 593
+T+ +PAP P A T+ + PT P PAP+ PP S E
Sbjct: 772 TTSDKPAPT-TPKETAPTT----PKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 594 TSVTFSPLKSPPQLERE-----MASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT 648
T++ SP +S P+L E + + P+ +P + + + ++ + KT + T
Sbjct: 826 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 885
Query: 649 PVHTSSKA--LLSTVLSRSQRTTQ----AAGGNVTSCLGSTSSPFVI 689
T++ A + + +++TT+ A VTS ++PF I
Sbjct: 886 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 932
Score = 108 bits (271), Expect = 3e-23
Identities = 145/624 (23%), Positives = 205/624 (32%), Gaps = 89/624 (14%)
Query: 178 TLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV 237
T P P TT P P PAP + P P + P P +
Sbjct: 499 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 238 PVQVATSVPAPSPP------------------LAPVPALAPAPPS----VPTLISDSNPL 275
P PAP+ P LAP PAP + PT + P
Sbjct: 559 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 618
Query: 276 SVSASVLVPVPASAP--PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP--SAPTLVLA 331
+ A+AP P P P + PAP + AP AP P +APT +
Sbjct: 619 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 678
Query: 332 PVPTPVLAPMP---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT--- 385
P PT P P A T P + P PT G T PA PAPT
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738
Query: 386 ---PAPIFTPAP-TPMPAATPAAIPTSAPIPASFSLSRVC--FPAAQAPAMQKVPLSFQP 439
P + PAP TP A PT+ P S + + P AP K P P
Sbjct: 739 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP---AP 795
Query: 440 GTVLTPSQPLVYIPPPSCGQPLSVATL--PTTLGVSSTLTLPVLPSYLQDRCL------P 491
T P+ PPP+ + + T PTT+ S + P L + + L P
Sbjct: 796 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Query: 492 GV-------LASPE-------------LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSP 531
GV PE LR+ P + A +T ++ + + T+
Sbjct: 856 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 915
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
+ T+ D P + T + KV T + + + P AK
Sbjct: 916 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI-MNKPEETAKPKDRATNSK 974
Query: 592 EGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVH 651
T P K+P + P ++ P + + P P ++ T MP L P
Sbjct: 975 ATTPKPQKPTKAPKK--------PTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 1025
Query: 652 TSSKALLSTVLSRSQR----------TTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
++A+L T +Q ++ AGG P V PE+ + D
Sbjct: 1026 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1085
Query: 702 WVKNSTALISTIPGTYVGVANPVP 725
V N +I+ + + N P
Sbjct: 1086 RVPNQGIIINPMLSDETNICNGKP 1109
Score = 102 bits (255), Expect = 2e-21
Identities = 137/553 (24%), Positives = 179/553 (32%), Gaps = 69/553 (12%)
Query: 200 PAPICPPAPGSAS----VPHSVPDAFQVPLSVPAPV-----PHSGLVPVQVATSVPAPSP 250
P P P P S + P ++ A P PAP P + P T PAP+
Sbjct: 309 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTTKEPAPTT 367
Query: 251 PLAPVPALA--PAPP---SVPTLISDSNPLSVS--ASVLVPVPASAPPSGPVPLSAPAPA 303
P P P PAP S PT + P + A PA P P P + PA
Sbjct: 368 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 427
Query: 304 PLSVPVSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPT-- 359
P + AP AP P APT P PT P P +T +P P P PT
Sbjct: 428 P-TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 486
Query: 360 -----------PTPSSGPPSTP-------TLIPAFA----PTPVPAPTPAPIFTPAPTPM 397
PT + P+TP T PA P P PAP P P
Sbjct: 487 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546
Query: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP-PPS 456
PA T P P + P AP K P LTP+ P P P
Sbjct: 547 TPKEPAPTTTKKPAPTT--------PKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPE 597
Query: 457 CGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPL-TSD 515
P + L T T T P P+ + A+P P + P T+
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA-----AAPNTPKEPAPTTPKEPAPTTP 652
Query: 516 SKLVSLEVNRLPCTSPSGSTTT---QPAP----DGVPGPLADTSLVTASAKVLPTPQPLL 568
+ T+P G+ T +PAP P LA T+ ++ P P
Sbjct: 653 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 712
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
P + + P PA T + LK P + +P E + + +
Sbjct: 713 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772
Query: 629 NRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGST--SSP 686
K ++T P P T+ K T TT T+ +T SP
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832
Query: 687 FVIFPEIVRNGDP 699
PE+ P
Sbjct: 833 DESTPELSAEPTP 845
Score = 94.4 bits (233), Expect = 9e-19
Identities = 139/555 (25%), Positives = 181/555 (32%), Gaps = 73/555 (13%)
Query: 286 PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPT-LVLAPVPTPVLAPMPAS 344
PA P P P + PA + P P + AP P P PT P P +
Sbjct: 301 PALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359
Query: 345 TPPAAPAPPSVPMPTPTPSSGPPST---PTLIPAFAPT--PVPAPT----PAPIFTPAPT 395
T AP P P PT T P +T PT APT PAPT PAP PT
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 419
Query: 396 PMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
P PA T P P + P AP K P P T P+ P P
Sbjct: 420 PTTPKEPAP-TTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTKEPSP 475
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
+ + PTT + T T P+ + SP P + P +
Sbjct: 476 TTPK----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 531
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS 575
K P+ +T +PAP P T+ A TP+ P +
Sbjct: 532 PK------------KPAPTTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKET 575
Query: 576 APPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPL 635
AP P K+ T ++ T +P K P E+A P E P + + P
Sbjct: 576 APTTPKKLTPTTPEKLAPT----TPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 629
Query: 636 PNQRKTPPMPVLT----PVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFP 691
TP P T P T+ K T + TT T + ++P P
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689
Query: 692 EIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPI 751
+ + +T ST P T G A P ++P +EP
Sbjct: 690 KEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTP--------------KEPAPTTPKEPA 733
Query: 752 SIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELS-LWKPTGP 810
PKGT T K E P+T K+ P +AP T S PT P
Sbjct: 734 PT----TPKGTAPTTLK-------EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782
Query: 811 ANIYPRCSVNGKPTS 825
P PT+
Sbjct: 783 KETAPTTPKEPAPTT 797
Score = 90.5 bits (223), Expect = 1e-17
Identities = 161/669 (24%), Positives = 222/669 (33%), Gaps = 101/669 (15%)
Query: 311 APPLALIQAPVPPS-----APTLVLAPVPTPVLAPMPASTPPAAPAP------PSVPM-P 358
AP ++ P P + P L PTP PAST P P P P+ P P
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPT----PAPIFTPAPTPMPAATPAAIPTSAPIPAS 414
PT + P+TP PA T PAPT PAP T P P T + PT+ PA
Sbjct: 341 APTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTPKEPAP 396
Query: 415 FSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
+ P AP K P P T P+ P P+ +P PTT
Sbjct: 397 TT------PKKPAPTTPKEP---APTTPKEPTPTTPKEPAPTTKEP-----APTT-PKEP 441
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
T P P+ P P P P T+ + P T+ S
Sbjct: 442 APTAPKKPA-------PTTPKEPA----PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490
Query: 535 TTTQPAPDGVPGPLADTSLVTASAKVLPT----PQPLLPAPSGSSAPPHPA----KMPSG 586
TTT+ P P S T + PT P P P + P PA K P+
Sbjct: 491 TTTKE-----PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPV 646
T + + T P + P+ E +P E ++ + +KL K P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPK-EPAPTTPKE--------TAPTTPKKLTPTTPEKLAPTTP 596
Query: 647 LTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS 706
P T+ + L T TT T + ++P P + P+T + +
Sbjct: 597 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 707 -TALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGAT 765
T T P T G A P +L K+P P K P + + T T
Sbjct: 657 PTTPKETAPTTPKGTA---PTTL---KEP------APTTPKKPAPKELAPTTTKEPTSTT 704
Query: 766 CGKKGSQAGAEGQPSTVKR---YTPARIAPGLP-GCQTKELSLWKPTGPANIYPR----C 817
C K P+T K TP AP P G L PT P P+
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764
Query: 818 SVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSS 877
+ G ++T P +P A + P+ P P SE S +
Sbjct: 765 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824
Query: 878 SEAVHGLPE-------GQPRPGGSFVPEQDPVTKNKTCRIAAKP-----YEEQVNPVLLT 925
+H P+ +P P ++P A KP +++ L
Sbjct: 825 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 884
Query: 926 LSPQTGTLA 934
+P+T T A
Sbjct: 885 TTPETTTAA 893
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 111 bits (278), Expect = 5e-24
Identities = 129/527 (24%), Positives = 187/527 (35%), Gaps = 39/527 (7%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P TT P P PAP + P P + P P + P T P+P+
Sbjct: 459 PTPTTPKEPAPTTK-EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT 517
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVP-VPASAPPSGPVPLSAPAPAPLSVP 308
P P P S PT + P + ++ P P+ P P + PAP +
Sbjct: 518 TPKEPAPT---TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574
Query: 309 VSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP 366
AP AP P APT P PT P P + AP P PT TP
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT-TPEKLA 633
Query: 367 PST-----PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAAT------PAAIPTSAPIPASF 415
P+T PT APT PTP PAPT AA PA P P +
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 416 SLSRVCFPAAQAPAMQK--VPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVS 473
P AP K P + + TP +P P+ + + T +
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 474 STLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSG 533
T P P + + P P T+ K E+ P+
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP-TTPKKPAPKELAPTTTKGPTS 812
Query: 534 STTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEG 593
+T+ +PAP P A T+ + PT P PAP+ PP S E
Sbjct: 813 TTSDKPAPT-TPKETAPTT----PKEPAPT-TPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 594 TSVTFSPLKSPPQLERE-----MASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT 648
T++ SP +S P+L E + + P+ +P + + + ++ + KT + T
Sbjct: 867 TTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT 926
Query: 649 PVHTSSKA--LLSTVLSRSQRTTQ----AAGGNVTSCLGSTSSPFVI 689
T++ A + + +++TT+ A VTS ++PF I
Sbjct: 927 TPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKI 973
Score = 108 bits (271), Expect = 3e-23
Identities = 145/624 (23%), Positives = 205/624 (32%), Gaps = 89/624 (14%)
Query: 178 TLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV 237
T P P TT P P PAP + P P + P P +
Sbjct: 540 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 238 PVQVATSVPAPSPP------------------LAPVPALAPAPPS----VPTLISDSNPL 275
P PAP+ P LAP PAP + PT + P
Sbjct: 600 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 659
Query: 276 SVSASVLVPVPASAP--PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPP--SAPTLVLA 331
+ A+AP P P P + PAP + AP AP P +APT +
Sbjct: 660 TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKE 719
Query: 332 PVPTPVLAPMP---ASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT--- 385
P PT P P A T P + P PT G T PA PAPT
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779
Query: 386 ---PAPIFTPAP-TPMPAATPAAIPTSAPIPASFSLSRVC--FPAAQAPAMQKVPLSFQP 439
P + PAP TP A PT+ P S + + P AP K P P
Sbjct: 780 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP---AP 836
Query: 440 GTVLTPSQPLVYIPPPSCGQPLSVATL--PTTLGVSSTLTLPVLPSYLQDRCL------P 491
T P+ PPP+ + + T PTT+ S + P L + + L P
Sbjct: 837 TTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Query: 492 GV-------LASPE-------------LRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSP 531
GV PE LR+ P + A +T ++ + + T+
Sbjct: 897 GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 956
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
+ T+ D P + T + KV T + + + P AK
Sbjct: 957 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEI-MNKPEETAKPKDRATNSK 1015
Query: 592 EGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVH 651
T P K+P + P ++ P + + P P ++ T MP L P
Sbjct: 1016 ATTPKPQKPTKAPKK--------PTSTKKPKTMPRVRKPKTTPTP-RKMTSTMPELNPTS 1066
Query: 652 TSSKALLSTVLSRSQR----------TTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPST 701
++A+L T +Q ++ AGG P V PE+ + D
Sbjct: 1067 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLP 1126
Query: 702 WVKNSTALISTIPGTYVGVANPVP 725
V N +I+ + + N P
Sbjct: 1127 RVPNQGIIINPMLSDETNICNGKP 1150
Score = 102 bits (255), Expect = 2e-21
Identities = 137/553 (24%), Positives = 179/553 (32%), Gaps = 69/553 (12%)
Query: 200 PAPICPPAPGSAS----VPHSVPDAFQVPLSVPAPV-----PHSGLVPVQVATSVPAPSP 250
P P P P S + P ++ A P PAP P + P T PAP+
Sbjct: 350 PTPTTPKEPASTTPKEPTPTTIKSAPTTPKE-PAPTTTKSAPTTPKEPAPTTTKEPAPTT 408
Query: 251 PLAPVPALA--PAPP---SVPTLISDSNPLSVS--ASVLVPVPASAPPSGPVPLSAPAPA 303
P P P PAP S PT + P + A PA P P P + PA
Sbjct: 409 PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPA 468
Query: 304 PLSVPVSAPPLALIQAPVPPS--APTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPT-- 359
P + AP AP P APT P PT P P +T +P P P PT
Sbjct: 469 P-TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTT 527
Query: 360 -----------PTPSSGPPSTP-------TLIPAFA----PTPVPAPTPAPIFTPAPTPM 397
PT + P+TP T PA P P PAP P P
Sbjct: 528 KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587
Query: 398 PAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIP-PPS 456
PA T P P + P AP K P LTP+ P P P
Sbjct: 588 TPKEPAPTTTKKPAPTT--------PKEPAPTTPKETAPTTP-KKLTPTTPEKLAPTTPE 638
Query: 457 CGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPL-TSD 515
P + L T T T P P+ + A+P P + P T+
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKA-----AAPNTPKEPAPTTPKEPAPTTP 693
Query: 516 SKLVSLEVNRLPCTSPSGSTTT---QPAP----DGVPGPLADTSLVTASAKVLPTPQPLL 568
+ T+P G+ T +PAP P LA T+ ++ P P
Sbjct: 694 KEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT 753
Query: 569 PAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKS 628
P + + P PA T + LK P + +P E + + +
Sbjct: 754 PKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813
Query: 629 NRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGST--SSP 686
K ++T P P T+ K T TT T+ +T SP
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873
Query: 687 FVIFPEIVRNGDP 699
PE+ P
Sbjct: 874 DESTPELSAEPTP 886
Score = 94.4 bits (233), Expect = 9e-19
Identities = 139/555 (25%), Positives = 181/555 (32%), Gaps = 73/555 (13%)
Query: 286 PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPT-LVLAPVPTPVLAPMPAS 344
PA P P P + PA + P P + AP P P PT P P +
Sbjct: 342 PALTTPKEPTPTTPKEPAS-TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400
Query: 345 TPPAAPAPPSVPMPTPTPSSGPPST---PTLIPAFAPT--PVPAPT----PAPIFTPAPT 395
T AP P P PT T P +T PT APT PAPT PAP PT
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 460
Query: 396 PMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
P PA T P P + P AP K P P T P+ P P
Sbjct: 461 PTTPKEPAP-TTKEPAPTTPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTKEPSP 516
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
+ + PTT + T T P+ + SP P + P +
Sbjct: 517 TTPK----EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTT 572
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSS 575
K P+ +T +PAP P T+ A TP+ P +
Sbjct: 573 PK------------KPAPTTPKEPAPTTPKEPAPTTTKKPAPT----TPKEPAPTTPKET 616
Query: 576 APPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPL 635
AP P K+ T ++ T +P K P E+A P E P + + P
Sbjct: 617 APTTPKKLTPTTPEKLAPT----TPEKPAPTTPEELA--PTTPEEPTPTTPEEPAPTTPK 670
Query: 636 PNQRKTPPMPVLT----PVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFP 691
TP P T P T+ K T + TT T + ++P P
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730
Query: 692 EIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPI 751
+ + +T ST P T G A P ++P +EP
Sbjct: 731 KEL--APTTTKEPTSTTCDKPAPTTPKGTAPTTP--------------KEPAPTTPKEPA 774
Query: 752 SIIDQGEPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELS-LWKPTGP 810
PKGT T K E P+T K+ P +AP T S PT P
Sbjct: 775 PT----TPKGTAPTTLK-------EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823
Query: 811 ANIYPRCSVNGKPTS 825
P PT+
Sbjct: 824 KETAPTTPKEPAPTT 838
Score = 90.5 bits (223), Expect = 1e-17
Identities = 161/669 (24%), Positives = 222/669 (33%), Gaps = 101/669 (15%)
Query: 311 APPLALIQAPVPPS-----APTLVLAPVPTPVLAPMPASTPPAAPAP------PSVPM-P 358
AP ++ P P + P L PTP PAST P P P P+ P P
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 359 TPTPSSGPPSTPTLIPAFAPTPVPAPT----PAPIFTPAPTPMPAATPAAIPTSAPIPAS 414
PT + P+TP PA T PAPT PAP T P P T + PT+ PA
Sbjct: 382 APTTTKSAPTTPK-EPAPTTTKEPAPTTPKEPAPTTTKEPAP---TTTKSAPTTPKEPAP 437
Query: 415 FSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
+ P AP K P P T P+ P P+ +P PTT
Sbjct: 438 TT------PKKPAPTTPKEP---APTTPKEPTPTTPKEPAPTTKEP-----APTT-PKEP 482
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
T P P+ P P P P T+ + P T+ S
Sbjct: 483 APTAPKKPA-------PTTPKEPA----PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531
Query: 535 TTTQPAPDGVPGPLADTSLVTASAKVLPT----PQPLLPAPSGSSAPPHPA----KMPSG 586
TTT+ P P S T + PT P P P + P PA K P+
Sbjct: 532 TTTKE-----PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPV 646
T + + T P + P+ E +P E ++ + +KL K P
Sbjct: 587 TTPKEPAPTTTKKPAPTTPK-EPAPTTPKE--------TAPTTPKKLTPTTPEKLAPTTP 637
Query: 647 LTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNS 706
P T+ + L T TT T + ++P P + P+T + +
Sbjct: 638 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 707 -TALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGAT 765
T T P T G A P +L K+P P K P + + T T
Sbjct: 698 PTTPKETAPTTPKGTA---PTTL---KEP------APTTPKKPAPKELAPTTTKEPTSTT 745
Query: 766 CGKKGSQAGAEGQPSTVKR---YTPARIAPGLP-GCQTKELSLWKPTGPANIYPR----C 817
C K P+T K TP AP P G L PT P P+
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805
Query: 818 SVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSS 877
+ G ++T P +P A + P+ P P SE S +
Sbjct: 806 TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865
Query: 878 SEAVHGLPE-------GQPRPGGSFVPEQDPVTKNKTCRIAAKP-----YEEQVNPVLLT 925
+H P+ +P P ++P A KP +++ L
Sbjct: 866 PTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR 925
Query: 926 LSPQTGTLA 934
+P+T T A
Sbjct: 926 TTPETTTAA 934
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 108 bits (269), Expect = 6e-23
Identities = 143/502 (28%), Positives = 181/502 (36%), Gaps = 79/502 (15%)
Query: 179 LGTGVPVEGTLPLVTTNFSPLPA-PICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV 237
LG P LP +T P A P PP G+ +P P + P P+P +G++
Sbjct: 873 LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932
Query: 238 PVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVP---ASAPPSGP 294
P+ P PP P A+ P PP I PL A + P P A PP P
Sbjct: 933 PLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP-GAGIPPPPPLPGAGIPPPPP 991
Query: 295 VP-LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMP-ASTPPAAPAP 352
+P P P PL PP L A +PP P L A +P P P+P A PP P P
Sbjct: 992 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPP--PPLPGAGIPPPPPLP 1048
Query: 353 -PSVPMPTPTPSSGPPSTPTLIPAFAPTP-------VPAPTPAP-IFTPAPTPMPAATPA 403
+P P P P +G P P L A P P +P P P P P P P+P
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG---V 1105
Query: 404 AIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPL--VYIPPPSCGQPL 461
IP P+P + P A P P PG + P PL V IPPP PL
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPGAGIP-----PPPPLPGAGIPPPPPLPRVGIPPP---PPL 1157
Query: 462 SVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSL 521
A +P + P P LPGV P L +
Sbjct: 1158 PGAGIPPPPPLPGAGIPPPPP-------LPGVGIPP-----------------PPPLPGV 1193
Query: 522 EVNRLPCTSPSGSTTTQPAPD-GVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHP 580
+ P +G P P G+P P P P LP P G+ PP P
Sbjct: 1194 GIPPPPPLPGAGIPPPPPLPGMGIP----------------PAPAPPLP-PPGTGIPPPP 1236
Query: 581 AKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRK 640
SG + S T PQ+ + P L ++ +K P+ R
Sbjct: 1237 LLPVSGPPLLPQVGSSTL----PTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292
Query: 641 TPPMPVLTPVHTSSKALLSTVL 662
P+ T + SK ST L
Sbjct: 1293 MKPL-YWTRIQLHSKRDSSTSL 1313
Score = 97.8 bits (242), Expect = 8e-20
Identities = 134/478 (28%), Positives = 170/478 (35%), Gaps = 78/478 (16%)
Query: 215 HSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS---PPLAPVPALAPAPPSVPTLISD 271
HSV AF+ ++P+P P L + ++S+P PP P+P + +VPTL S
Sbjct: 843 HSVSSAFKNSCNIPSPPP---LPCTESSSSMPGLGMVPPPPPPLPGM-----TVPTLPST 894
Query: 272 S--NPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLV 329
+ P + + ++P P P +P P P +P+ PPL P PP P
Sbjct: 895 AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPL--PPLPGAGIPPPPPLPGAA 952
Query: 330 LAPVPT------PVLAPMP-ASTPPAAPAPPS-VPMPTPTPSSGPPSTPTLIPAFAPTPV 381
+ P P P+ P+P A PP P P + +P P P P +G P P L A P P
Sbjct: 953 IPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1012
Query: 382 PAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT 441
P P P P P+P A IP P+P + P A P P PG
Sbjct: 1013 PLPGAG---IPPPPPLPG---AGIPPPPPLPGAGIPPPPPLPGAGIP-----PPPPLPGA 1061
Query: 442 VLTPSQPL--VYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPEL 499
+ P PL IPPP PL A +P + P P LPGV P
Sbjct: 1062 GIPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPPPP-------LPGVGIPPPP 1111
Query: 500 RSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPD----GVPGPLADTSLVT 555
PL +P P P P G+P P
Sbjct: 1112 PLPGAGIPPPPPLPGAG---------IPPPPPLPGAGIPPPPPLPRVGIPPP------PP 1156
Query: 556 ASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPP 615
+P P PL G+ PP P G V P PP L PP
Sbjct: 1157 LPGAGIPPPPPL----PGAGIPPPPPLPGVGIPPPPPLPGVGIPP---PPPLPGAGIPPP 1209
Query: 616 ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAG 673
PL PLP P P L PV S LL V S + T Q G
Sbjct: 1210 P----PLPGMGIPPAPAPPLPPPGTGIPPPPLLPV--SGPPLLPQVGSSTLPTPQVCG 1261
Score = 38.1 bits (87), Expect = 0.074
Identities = 44/187 (23%), Positives = 69/187 (36%), Gaps = 33/187 (17%)
Query: 539 PAPDGVP---GPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTS 595
P+P G+P P + A T P A G A P + T+++ E +
Sbjct: 294 PSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDA 353
Query: 596 VTFSPLKSPPQ---------LEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPV 646
+P SP + + + PE D + ++ P P+QR P P+
Sbjct: 354 FEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPL 413
Query: 647 LTP--VHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVK 704
+TP + T+++ L S S SQ Q+ P I R +PS
Sbjct: 414 ITPCYIKTTTRQLSSPNHSPSQSPNQS-------------------PRIKRRPEPSLSRG 454
Query: 705 NSTALIS 711
+ TAL S
Sbjct: 455 SRTALAS 461
Score = 34.7 bits (78), Expect = 0.82
Identities = 46/188 (24%), Positives = 64/188 (34%), Gaps = 23/188 (12%)
Query: 201 APICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAP 260
AP P + S +P++ P P G +PV A S+PA PA
Sbjct: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQ------PAAKD 316
Query: 261 APPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAP--------APLSVPVSAP 312
+P S ++ P +A V G AP AP V AP
Sbjct: 317 SPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAP-EVGEDAP 375
Query: 313 ------PLALIQAPVPPSAPTLVLAPVPTP-VLAPMPASTP-PAAPAPPSVPMPTPTPSS 364
P Q P P+A +L +P P+ P P TP + P +PS
Sbjct: 376 QRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQ 435
Query: 365 GPPSTPTL 372
P +P +
Sbjct: 436 SPNQSPRI 443
>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
Length = 2639
Score = 107 bits (267), Expect = 1e-22
Identities = 134/535 (25%), Positives = 197/535 (36%), Gaps = 93/535 (17%)
Query: 243 TSVPAPSP-PLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA 301
T+ P+P P+ + P P T + P++ + +V P P P + P
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTV---TPTPTPTGTQTPTTTPI 1362
Query: 302 PAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPT 361
+V + P P T + P PTP P ST P P PTPT
Sbjct: 1363 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTST-PITTTTTVTPTPTPT 1421
Query: 362 PSSGPPSTP-----TLIPAFAPTPVPAPTPAPIFTPAP-TPMPAATPAAIPTSAPIPASF 415
+ P +TP T+ P PT APTP I T + TP P T PT+ PI +
Sbjct: 1422 GTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTT 1481
Query: 416 SLSRVCFP-AAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
+++ P Q P P + T +TP+ P P+ Q PT+ +++
Sbjct: 1482 TVTPTPTPTGTQTP----TPTAITTTTTVTPT------PTPTGTQ------TPTSTPITT 1525
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
T T+ P+ P +P P S +T + P T+P +
Sbjct: 1526 TTTVTPTPT-------PTGTQTPT----PTPISTTTTVTPTPTPTGTQT---PTTTPITT 1571
Query: 535 TTT---QPAPDGVPGPLADTSLVTASAKVLPTPQP-------LLPAPSGSSAPPHPAKMP 584
TTT P P G P T L+T + + PTP P + P + ++ P P
Sbjct: 1572 TTTVTPTPTPTGTQTP--TTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPT--P 1627
Query: 585 SGTEQQTE---GTSVTFSPLKSP--------------PQLEREMASPPECSEMPLDLSSK 627
+GT+ T T+ T +P +P P E ++PP S P S
Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 1687
Query: 628 SN--------RQKLP--LPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVT 677
S+ LP + PP P TS LS TT + G T
Sbjct: 1688 SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----GHTLSPPPSTTTSPPGTPT 1743
Query: 678 --SCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPASLLL 730
+ GS+S+P P V+ S W T L + G+ P P+S+L+
Sbjct: 1744 RGTTTGSSSAP---TPSTVQTTTTSAWTPTPTPLSTPSIIRTTGL-RPYPSSVLI 1794
Score = 99.4 bits (246), Expect = 3e-20
Identities = 144/593 (24%), Positives = 194/593 (32%), Gaps = 104/593 (17%)
Query: 142 TPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTN-FSPLP 200
TP+ T + +P G + + + T TG T P+ TT +P P
Sbjct: 1337 TPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1395
Query: 201 APICPPAPGSASV-------PHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPP-L 252
P P S + P P Q P + P + + P T AP+P +
Sbjct: 1396 TPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-VTPTPTPTGTQAPTPTAI 1454
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLS---------APAPA 303
+ P P T + P++ + +V P P P P + P P
Sbjct: 1455 TTTSTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTPTAITTTTTVTPTPTPT 1513
Query: 304 PLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPM---PASTPPAAPAPPSVPM--- 357
P S P + P PT P PTP+ P TP P + P+
Sbjct: 1514 GTQTPTSTP-ITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTT 1572
Query: 358 ----PTPTPSSGPPSTPTLIPA---FAPTPVPAPTPAPIFTP---------APTPMPAAT 401
PTPTP+ T LI PTP P T + TP PTP T
Sbjct: 1573 TTVTPTPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQT 1632
Query: 402 PAAIP-------TSAPIPASFSLSRVCF----PAAQAPAMQKVPLSFQPGTVLTPSQPLV 450
P IP T P P + S P A+ P S P T + S PL
Sbjct: 1633 PTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 1692
Query: 451 Y-------IPPP---SCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR 500
+PP + P S T PTT TL+ P PS PG +P
Sbjct: 1693 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPP--PSTTTSP--PG---TPTRG 1745
Query: 501 SYPYAFSVARPLTSDSKLVSLEV-NRLPCTSPSGSTTT--QPAPDGV------------- 544
+ + S P T + S P ++PS TT +P P V
Sbjct: 1746 TTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAP 1805
Query: 545 -----PGPLADTS-LVTASAKVL------PTPQPLLPAPSGSSAPPHPAKMPSGTEQQTE 592
G DT V S P P P+ S + P P+K S + T
Sbjct: 1806 GEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTP 1865
Query: 593 GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMP 645
GT P PP+ E E +C + K N + + + PPMP
Sbjct: 1866 GTKPPECPDFDPPRQENETWWLCDC----FMATCKYNNTVEIVKVECEPPPMP 1914
Score = 48.1 bits (113), Expect = 7e-05
Identities = 92/453 (20%), Positives = 148/453 (32%), Gaps = 70/453 (15%)
Query: 527 PCTSPSGSTTT-QPAPDGVPGPLADTSLVTASAKVLPTPQPL-----LPAPSGSSAPPHP 580
P +P +TTT P P + +T + V PTP P P ++ P
Sbjct: 1311 PTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1370
Query: 581 AKMPSGTEQQTE---GTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPN 637
P+GT+ T T+ T +P +P + ++P +++ + P P
Sbjct: 1371 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTP---------ITTTTTVTPTPTPT 1421
Query: 638 QRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNG 697
+T P TP+ T++ + + +Q T A +T+S P
Sbjct: 1422 GTQT---PTTTPITTTTTVTPTPTPTGTQAPTPTA--------ITTTSTVTPTPTPTGTQ 1470
Query: 698 DPSTWVKNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDPRHLPKQEPISIIDQG 757
P+T +T ++ P T G P P ++ P PI+
Sbjct: 1471 TPTTTPITTTTTVTPTP-TPTGTQTPTPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1529
Query: 758 EPKGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRC 817
P T G+Q ST TP P G QT + T + P
Sbjct: 1530 TPTPT-----PTGTQTPTPTPISTTTTVTP---TPTPTGTQTPTTT--PITTTTTVTPTP 1579
Query: 818 SVNGKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSS 877
+ G T T VL I++ +TP+ PT ++ + V +++
Sbjct: 1580 TPTGTQTPTTVL----------------ITTTTTMTPT------PTPTSTKSTTVTPITT 1617
Query: 878 SEAVHGLPEGQPRPGGSFVPEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSV 937
+ V P P G+ P P++ T P P T + L S
Sbjct: 1618 TTTV----TATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSN 1673
Query: 938 QPSGGDI----RMNQGPEESESHLCSDSTPKME 966
P R P + L S P +E
Sbjct: 1674 PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIE 1706
Score = 40.0 bits (92), Expect = 0.019
Identities = 68/336 (20%), Positives = 103/336 (30%), Gaps = 50/336 (14%)
Query: 616 ECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGN 675
EC P +++ + P P T P TP T S + + T G
Sbjct: 1295 ECVTQPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGT 1354
Query: 676 VTSCLGSTSSPFVIFPEIVRNG--DPSTWVKNSTALISTIP---GTYVGVANPVPASLLL 730
T ++ + P G P+T +T ++ P GT + P+ + +
Sbjct: 1355 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTV 1414
Query: 731 NKDPNLGLNRDPRHLPKQEPISIIDQGEPKGTGA--------------TCGKKGSQAGAE 776
P + P P ++ P GT A T G+Q
Sbjct: 1415 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTT 1474
Query: 777 GQPSTVKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPY 836
+T TP P G QT PT P I +V PT T +P
Sbjct: 1475 TPITTTTTVTP---TPTPTGTQT-------PT-PTAITTTTTVTPTPTPTGTQTPTSTPI 1523
Query: 837 HQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFV 896
+ ++ + G TP+ PI T+ V+ P P G+
Sbjct: 1524 TTTTTVTPTPTPTGTQTPTP-TPISTTTTVTP-------------------TPTPTGTQT 1563
Query: 897 PEQDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGT 932
P P+T T P Q +L + T T
Sbjct: 1564 PTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMT 1599
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 106 bits (264), Expect = 2e-22
Identities = 151/595 (25%), Positives = 218/595 (36%), Gaps = 106/595 (17%)
Query: 65 VGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSPGDGLKL 124
VGS ARG P + H +P P+P+ EA+ L+P + P L
Sbjct: 558 VGSPDKARGP-PVPLQVQVTYHAQAGQPGPPEPEEP------EADQHLLPPTLPTSATSL 610
Query: 125 PAS---DSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSR---------QGVGEKN 172
+ DS + S +D + + + D +P+ + + S Q +
Sbjct: 611 ASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLG 670
Query: 173 TFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPA-------PGSASVPHSVPDAFQVPL 225
+ T G+PV +PAP CPP+ P + P P + +P
Sbjct: 671 AYQQPTAAPGLPV-----------GSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPT 719
Query: 226 SVPAPVPHSGLVPVQVATSVPAPSPPLAPVPA--LAPAPPSVPTLISDSN---------P 274
P P G P +A P P LAP P L P PP +P ++ ++ P
Sbjct: 720 GPGQPAP-PGQQPPPLAQPTPLPQV-LAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKP 777
Query: 275 LSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQA--PVPPSAPTLVLAP 332
L + + L P+ P P+P+ P PLA I P P PT + P
Sbjct: 778 LQMPQAPLQPLAQVPPQMPPIPVVPP----------ITPLAGIDGLPPALPDLPTATVPP 827
Query: 333 VPTP-------VLAPMPASTPPAAPAPPSVPMPTPTPSSGP---------PSTPTLIP-- 374
VP P +L + A PPA+PA P + P P P P+ P IP
Sbjct: 828 VPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLL 887
Query: 375 AFAPTPVPAPT--PAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQK 432
A AP V A + A P PAA P PT P ++ + Q PA+
Sbjct: 888 AVAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQ-PALPP 946
Query: 433 VPLSFQPGTVLTPS---QPLVYIPPPSCGQPLSV----ATLPTTLGVSSTLTLPVLPSYL 485
P + P VL P P +PP P V LP + LPV P L
Sbjct: 947 QP-TLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVRPEPL 1005
Query: 486 Q----DRCLPGVLASPEL---RSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQ 538
Q ++ P ++ PYA VA +++ ++ V SP
Sbjct: 1006 QPHLPEQAAPAATPGSQILLGHPAPYAVDVA------AQVPTVPVPPAAVLSPPLPEVLL 1059
Query: 539 P-APDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPA-KMPSGTEQQT 591
P AP+ +P + + V+AS + +PT L P+ P P P T Q T
Sbjct: 1060 PAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPPLPGGPGIASPCPTVQLT 1114
Score = 101 bits (251), Expect = 7e-21
Identities = 145/549 (26%), Positives = 196/549 (35%), Gaps = 93/549 (16%)
Query: 230 PVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPT----LISDSNPLSVSASVLVPV 285
PVP V P P P P PP++PT L SDS S S +
Sbjct: 568 PVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSD 627
Query: 286 PASAPPS---GPVPLSAPAPA------PLS----VPVSAPPLALIQAPVPPSAPTLVLAP 332
S+ S G + +AP+PA P+S +P S P L Q P +AP L +
Sbjct: 628 SQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPT--AAPGLPVGS 685
Query: 333 VPTPVLAPM-------PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT 385
VP P P PA + PPS PMPT PP P P+ PT
Sbjct: 686 VPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQ-------PPPLAQPT 738
Query: 386 PAP-IFTPAPT----PMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPG 440
P P + P P P+P P + ++ + A L + P A + +VP P
Sbjct: 739 PLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI 798
Query: 441 TVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELR 500
V+ P PL I G P ++ LPT T+P +P P SP +
Sbjct: 799 PVVPPITPLAGID----GLPPALPDLPTA-------TVPPVP--------PPQYFSPAV- 838
Query: 501 SYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQP-------APDGVP----GPLA 549
S+A PL S + L+ +LP P G+ P AP +P P
Sbjct: 839 ---ILPSLAAPLPPASPALPLQAVKLP--HPPGAPLAMPCRTIVPNAPATIPLLAVAPPG 893
Query: 550 DTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLER 609
+L SA QP+ PA AP P T Q T L P L
Sbjct: 894 VAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQ-PALPPQPTLPP 952
Query: 610 EMASPPECSEMPLD-LSSKSNRQKLP-LPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQR 667
+ PP+ + P L + R P LP Q PP PVL P Q
Sbjct: 953 QPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPP----------------QP 996
Query: 668 TTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVANPVPAS 727
+ L ++P + G P+ + + A + T+P V +P
Sbjct: 997 ALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPE 1056
Query: 728 LLLNKDPNL 736
+LL P L
Sbjct: 1057 VLLPAAPEL 1065
Score = 72.0 bits (175), Expect = 5e-12
Identities = 108/434 (24%), Positives = 162/434 (37%), Gaps = 47/434 (10%)
Query: 205 PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPS 264
PP P S+ P + D+ + + S L Q+ + +PP AP LAP+ P
Sbjct: 1331 PPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPP 1390
Query: 265 VPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPS 324
V L D + A+ +P PAS S P + S P +AP+
Sbjct: 1391 VTALPQDG---AAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQ 1447
Query: 325 APTLVLAP-VPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPA-FAPTPVP 382
+ LAP P P A ++ P P PP P P P+P SG P PA P V
Sbjct: 1448 PLVVGLAPCTPAPEAASTRDASAPREPLPP--PAPEPSPHSGTPQPALGQPAPLLPAAVG 1505
Query: 383 APTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTV 442
A + A P+P P+ P P++ RV F + ++ + + T+
Sbjct: 1506 AVSLATSQLPSP-PLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDE-----KLRTL 1559
Query: 443 LTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPEL--R 500
L Q V S G P+ V TL P+ + G LA P +
Sbjct: 1560 L--YQEHVPTSSASAGTPVEVGDRDFTLE-------PLRGDQPRSEVCGGDLALPPVPKE 1610
Query: 501 SYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKV 560
+ + +PL S+L + S S T + +P + G D V + + V
Sbjct: 1611 AVSGRVQLPQPLVEKSELAPTR-GAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHV 1669
Query: 561 LPTPQPLLPA----------------PSGSSAPPHPAKMPS----GTEQQTEGTSVTFSP 600
+P+ +PA SSA P P+ M + + QT G SP
Sbjct: 1670 VPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSP 1729
Query: 601 LKSPPQLEREMASP 614
K P Q ++++SP
Sbjct: 1730 RKRPEQ--QDVSSP 1741
Score = 60.1 bits (144), Expect = 2e-08
Identities = 59/208 (28%), Positives = 73/208 (35%), Gaps = 35/208 (16%)
Query: 200 PAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALA 259
P P PP P P P P V P P P P L P P L
Sbjct: 940 PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQP------------TRPPQPVLPPQPMLP 987
Query: 260 PAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQA 319
P P P P + + +A P + L PAP + V P +
Sbjct: 988 PQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTV----- 1042
Query: 320 PVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA-----PPSVPMPTPTPSSGPPSTPTLIP 374
PVPP+A VL+P P+P PAAP P S+ + + S P T TL+P
Sbjct: 1043 PVPPAA---VLSP-------PLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092
Query: 375 AFAPTPVPAPTPAPIFTPAPTPMPAATP 402
P P P I +P PT P
Sbjct: 1093 ---PANPPLPGGPGIASPCPTVQLTVEP 1117
Score = 45.4 bits (106), Expect = 5e-04
Identities = 89/315 (28%), Positives = 112/315 (35%), Gaps = 54/315 (17%)
Query: 382 PAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASF-SLSRVCFPAAQAPAMQKVPLSFQPG 440
PAP AP +P P P+ + P A SAP S + F A+Q Q P S PG
Sbjct: 1322 PAPE-APESSP-PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP-SNPPG 1378
Query: 441 TVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRC----LPGVLAS 496
P PL PP V LP +T T+P S + P L S
Sbjct: 1379 ---APPAPLAPSSPP-------VTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTS 1428
Query: 497 PELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTA 556
S P A + PL +V L PCT PAP+ A T +A
Sbjct: 1429 ELETSQPLAETHEAPLAVQPLVVGL----APCT---------PAPEA-----ASTRDASA 1470
Query: 557 SAKVLPTPQPLLPAPSGSSAPPHPA-KMPSGTEQQTEG-TSVTFSPLKSPPQLEREMASP 614
+ LP P P PS S P PA P+ G S+ S L SPP P
Sbjct: 1471 PREPLPPP---APEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQP 1527
Query: 615 PECSEMP----------LDLSSKSNRQKL-PLPNQRKTPPMPVL--TPVHTSSKALLSTV 661
P E +D + KS +KL L Q P TPV +
Sbjct: 1528 PSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEP 1587
Query: 662 LSRSQRTTQAAGGNV 676
L Q ++ GG++
Sbjct: 1588 LRGDQPRSEVCGGDL 1602
Score = 43.5 bits (101), Expect = 0.002
Identities = 74/276 (26%), Positives = 100/276 (36%), Gaps = 75/276 (27%)
Query: 180 GTGVP------VEGTLPLVTTNFSPLPA-PI------CPPAPGSASVPHSVPDAFQVPLS 226
G G P +E + PL T+ +PL P+ C PAP +AS + +P
Sbjct: 1419 GPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPP 1478
Query: 227 VPAPVPHSG-----------LVP-----VQVATSVPAPSPPLAPVPALAPAPPS------ 264
P P PHSG L+P V +ATS PSPPL P + P PPS
Sbjct: 1479 APEPSPHSGTPQPALGQPAPLLPAAVGAVSLATS-QLPSPPLG--PTVPPQPPSALESDG 1535
Query: 265 --------------------VPTLISDSNPLSVSASVLVPVPAS------APPSGPVPLS 298
+ TL+ + + SAS PV P G P S
Sbjct: 1536 EGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRS 1595
Query: 299 APAPAPLSVPVSAPPLAL---IQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSV 355
L++P P A+ +Q P P LAP V+ +S+ A +P S+
Sbjct: 1596 EVCGGDLALP-PVPKEAVSGRVQLP-QPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSM 1653
Query: 356 ------PMPTPTPSSGPPSTPTLIPAFAPTPVPAPT 385
+ S PS P +PAF PT
Sbjct: 1654 LGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPT 1689
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 102 bits (255), Expect = 2e-21
Identities = 77/249 (30%), Positives = 102/249 (40%), Gaps = 24/249 (9%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSG--LVPVQVATSVPA 247
P +T + +P P P +S P P S P P S L P T P+
Sbjct: 56 PTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 115
Query: 248 PSPPLAP--VPALAPA------PPSVPTLISDSNPLSVSASVLVPVPASAP--------- 290
+P L P P L P+ P S PTL S P+ +S P+S P
Sbjct: 116 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 291 --PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPA 348
PS P P+ P P S P L P+ + T L P P+L P+STP
Sbjct: 176 LTPSS-TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILT--PSSTPTL 232
Query: 349 APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408
P+ + + TP+ P STPTL P+ PT P+ TP + PT P++TP P+S
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSS 292
Query: 409 APIPASFSL 417
P SL
Sbjct: 293 TPTLTPSSL 301
Score = 100 bits (248), Expect = 2e-20
Identities = 102/365 (27%), Positives = 143/365 (39%), Gaps = 74/365 (20%)
Query: 243 TSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAP 300
T P+ +P L P P S PTL S P+ +S P+S P P P P
Sbjct: 1 TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60
Query: 301 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP 360
+ P P S P L P S PTL P P+L +STP P+ P P+
Sbjct: 61 SNTPTLTPSSTPTLT------PSSTPTLT----PQPILTR--SSTPTLTPSSPPTLTPSN 108
Query: 361 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV 420
TP+ P +TPTL P+ PT P+ TP T P++TP P+S PI L+R
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTP--------TLTPSSTPTLTPSSRPI-----LTRS 155
Query: 421 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
P LTPS +P+ + TL SST TL
Sbjct: 156 STPT------------------LTPSS-----------RPILTRSSTPTLTPSSTPTLT- 185
Query: 481 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540
P + S P +RP+ + S +L + P +PS + T P+
Sbjct: 186 ----------PSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPS 235
Query: 541 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPH-PAKMPSGTEQQTEGTSVTFS 599
+ L +S T + PT L P+ + + P + P PS T T ++ T +
Sbjct: 236 SRPI---LTRSSTPTLTPSSTPT---LTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLT 289
Query: 600 PLKSP 604
P +P
Sbjct: 290 PSSTP 294
Score = 95.9 bits (237), Expect = 3e-19
Identities = 93/307 (30%), Positives = 120/307 (39%), Gaps = 32/307 (10%)
Query: 192 VTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPL--SVPAPVPHSG--LVPVQVATSVPA 247
+T + +P P PP +S P P + + S P P S L P T P+
Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61
Query: 248 PSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAPAPAPL 305
+P L P P S PTL P+ +S P+S P P P P+ P
Sbjct: 62 NTPTLTPSSTPTLTPSSTPTL--TPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Query: 306 SVPVSAPPLALIQAP--VPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPS 363
P + P L P P S PTL + P + P TP + P PT TPS
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 364 S----GPPSTPTLIPAFAPTPVPAPTP------APIFTPAPTPM--PAATPAAIPTSAPI 411
S P STPTL P+ PT P+ P P TP+ P+ P++TP P+S PI
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239
Query: 412 PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLG 471
L+R P + + S P LTPS P P + TL
Sbjct: 240 -----LTRSSTPTLTPSSTPTLTPSNTP--TLTPSNTPTLTP---SNTPTLTPSSTPTLT 289
Query: 472 VSSTLTL 478
SST TL
Sbjct: 290 PSSTPTL 296
Score = 93.2 bits (230), Expect = 2e-18
Identities = 73/247 (29%), Positives = 94/247 (38%), Gaps = 26/247 (10%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQV----------PLSVPAPVPHSGLVPV 239
P++T + +P P PP ++ P P P S P P L
Sbjct: 32 PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRS 91
Query: 240 QVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV--PL 297
T P+ P L P P + PTL + P +S P+S P P P+
Sbjct: 92 STPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPI 151
Query: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAP--MPASTPPAAPAPPSV 355
+ P P S P L P + T L P TP L P P TP + P
Sbjct: 152 LTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRS 211
Query: 356 PMPTPTPSS----GPPSTPTLIPAFAP------TPVPAPTPAPIFTPAPTP--MPAATPA 403
PT TPSS P STPTL P+ P TP P+ P TP+ TP P+ TP
Sbjct: 212 STPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Query: 404 AIPTSAP 410
P++ P
Sbjct: 272 LTPSNTP 278
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/221 (28%), Positives = 86/221 (38%), Gaps = 24/221 (10%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P++T + +P P PP ++ P P P P+ P L P T P+ +
Sbjct: 86 PILTRSSTPTLTPSSPPTLTPSNTPTLTPS--NTPTLTPSNTPT--LTPSSTPTLTPSST 141
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAPAPAPLSV 307
P L P S PTL S P+ +S P+S P P P P+ P
Sbjct: 142 PTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201
Query: 308 PVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPM--------------PASTPPAAPA-- 351
P S P L P + +L P TP L P P+STP P+
Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNT 261
Query: 352 PPSVPMPTPT--PSSGPPSTPTLIPAFAPTPVPAPTPAPIF 390
P P TPT PS+ P TP+ P P+ P TP+ ++
Sbjct: 262 PTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSLW 302
Score = 69.3 bits (168), Expect = 3e-11
Identities = 55/212 (25%), Positives = 77/212 (36%), Gaps = 28/212 (13%)
Query: 172 NTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV 231
NT L T + P +T + +P P P +S P P + + P
Sbjct: 116 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 232 PHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291
P +S P + P S PTL S P+ +S
Sbjct: 176 LTPSSTPTLTPSSTPTLT------------PSSTPTLTPSSRPILTRSS----------- 212
Query: 292 SGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351
P P+ P+ P S P L P+ + T L P TP L P++TP P+
Sbjct: 213 ---TPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLT--PSNTPTLTPS 267
Query: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA 383
P+ TP+ P STPTL P+ PT P+
Sbjct: 268 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 299
Score = 42.0 bits (97), Expect = 0.005
Identities = 42/182 (23%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 142 TPLNTQM---SKQVDCSPAGVKAL--DSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNF 196
TP NT S +P+ L SR + +T L + + P +T +
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180
Query: 197 SPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPV- 255
+P P P +S P P + + P P+ +S P +P P+
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240
Query: 256 -----PALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVS 310
P L P+ S PTL + P ++ P++ P P S P P S P
Sbjct: 241 TRSSTPTLTPS--STPTLTPSNTPTLTPSNTPTLTPSNTPTL--TPSSTPTLTPSSTPTL 296
Query: 311 AP 312
P
Sbjct: 297 TP 298
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 102 bits (255), Expect = 2e-21
Identities = 77/249 (30%), Positives = 102/249 (40%), Gaps = 24/249 (9%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSG--LVPVQVATSVPA 247
P +T + +P P P +S P P S P P S L P T P+
Sbjct: 56 PTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 115
Query: 248 PSPPLAP--VPALAPA------PPSVPTLISDSNPLSVSASVLVPVPASAP--------- 290
+P L P P L P+ P S PTL S P+ +S P+S P
Sbjct: 116 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 291 --PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPA 348
PS P P+ P P S P L P+ + T L P P+L P+STP
Sbjct: 176 LTPSS-TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILT--PSSTPTL 232
Query: 349 APAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408
P+ + + TP+ P STPTL P+ PT P+ TP + PT P++TP P+S
Sbjct: 233 TPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSS 292
Query: 409 APIPASFSL 417
P SL
Sbjct: 293 TPTLTPSSL 301
Score = 100 bits (248), Expect = 2e-20
Identities = 102/365 (27%), Positives = 143/365 (39%), Gaps = 74/365 (20%)
Query: 243 TSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAP 300
T P+ +P L P P S PTL S P+ +S P+S P P P P
Sbjct: 1 TLTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTP 60
Query: 301 APAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTP 360
+ P P S P L P S PTL P P+L +STP P+ P P+
Sbjct: 61 SNTPTLTPSSTPTLT------PSSTPTLT----PQPILTR--SSTPTLTPSSPPTLTPSN 108
Query: 361 TPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRV 420
TP+ P +TPTL P+ PT P+ TP T P++TP P+S PI L+R
Sbjct: 109 TPTLTPSNTPTLTPSNTPTLTPSSTP--------TLTPSSTPTLTPSSRPI-----LTRS 155
Query: 421 CFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPV 480
P LTPS +P+ + TL SST TL
Sbjct: 156 STPT------------------LTPSS-----------RPILTRSSTPTLTPSSTPTLT- 185
Query: 481 LPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPA 540
P + S P +RP+ + S +L + P +PS + T P+
Sbjct: 186 ----------PSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPS 235
Query: 541 PDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPH-PAKMPSGTEQQTEGTSVTFS 599
+ L +S T + PT L P+ + + P + P PS T T ++ T +
Sbjct: 236 SRPI---LTRSSTPTLTPSSTPT---LTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLT 289
Query: 600 PLKSP 604
P +P
Sbjct: 290 PSSTP 294
Score = 95.9 bits (237), Expect = 3e-19
Identities = 93/307 (30%), Positives = 120/307 (39%), Gaps = 32/307 (10%)
Query: 192 VTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPL--SVPAPVPHSG--LVPVQVATSVPA 247
+T + +P P PP +S P P + + S P P S L P T P+
Sbjct: 2 LTPSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPS 61
Query: 248 PSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAPAPAPL 305
+P L P P S PTL P+ +S P+S P P P P+ P
Sbjct: 62 NTPTLTPSSTPTLTPSSTPTL--TPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPT 119
Query: 306 SVPVSAPPLALIQAP--VPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPS 363
P + P L P P S PTL + P + P TP + P PT TPS
Sbjct: 120 LTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 364 S----GPPSTPTLIPAFAPTPVPAPTP------APIFTPAPTPM--PAATPAAIPTSAPI 411
S P STPTL P+ PT P+ P P TP+ P+ P++TP P+S PI
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPI 239
Query: 412 PASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLG 471
L+R P + + S P LTPS P P + TL
Sbjct: 240 -----LTRSSTPTLTPSSTPTLTPSNTP--TLTPSNTPTLTP---SNTPTLTPSSTPTLT 289
Query: 472 VSSTLTL 478
SST TL
Sbjct: 290 PSSTPTL 296
Score = 93.2 bits (230), Expect = 2e-18
Identities = 73/247 (29%), Positives = 94/247 (38%), Gaps = 26/247 (10%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQV----------PLSVPAPVPHSGLVPV 239
P++T + +P P PP ++ P P P S P P L
Sbjct: 32 PILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPQPILTRS 91
Query: 240 QVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPV--PL 297
T P+ P L P P + PTL + P +S P+S P P P+
Sbjct: 92 STPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPI 151
Query: 298 SAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAP--MPASTPPAAPAPPSV 355
+ P P S P L P + T L P TP L P P TP + P
Sbjct: 152 LTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRS 211
Query: 356 PMPTPTPSS----GPPSTPTLIPAFAP------TPVPAPTPAPIFTPAPTP--MPAATPA 403
PT TPSS P STPTL P+ P TP P+ P TP+ TP P+ TP
Sbjct: 212 STPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Query: 404 AIPTSAP 410
P++ P
Sbjct: 272 LTPSNTP 278
Score = 84.0 bits (206), Expect = 1e-15
Identities = 63/221 (28%), Positives = 86/221 (38%), Gaps = 24/221 (10%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
P++T + +P P PP ++ P P P P+ P L P T P+ +
Sbjct: 86 PILTRSSTPTLTPSSPPTLTPSNTPTLTPS--NTPTLTPSNTPT--LTPSSTPTLTPSST 141
Query: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VPLSAPAPAPLSV 307
P L P S PTL S P+ +S P+S P P P P+ P
Sbjct: 142 PTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201
Query: 308 PVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPM--------------PASTPPAAPA-- 351
P S P L P + +L P TP L P P+STP P+
Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNT 261
Query: 352 PPSVPMPTPT--PSSGPPSTPTLIPAFAPTPVPAPTPAPIF 390
P P TPT PS+ P TP+ P P+ P TP+ ++
Sbjct: 262 PTLTPSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSLW 302
Score = 69.3 bits (168), Expect = 3e-11
Identities = 55/212 (25%), Positives = 77/212 (36%), Gaps = 28/212 (13%)
Query: 172 NTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV 231
NT L T + P +T + +P P P +S P P + + P
Sbjct: 116 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPT 175
Query: 232 PHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291
P +S P + P S PTL S P+ +S
Sbjct: 176 LTPSSTPTLTPSSTPTLT------------PSSTPTLTPSSRPILTRSS----------- 212
Query: 292 SGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351
P P+ P+ P S P L P+ + T L P TP L P++TP P+
Sbjct: 213 ---TPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLT--PSNTPTLTPS 267
Query: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA 383
P+ TP+ P STPTL P+ PT P+
Sbjct: 268 NTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 299
Score = 42.0 bits (97), Expect = 0.005
Identities = 42/182 (23%), Positives = 64/182 (35%), Gaps = 15/182 (8%)
Query: 142 TPLNTQM---SKQVDCSPAGVKAL--DSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNF 196
TP NT S +P+ L SR + +T L + + P +T +
Sbjct: 121 TPSNTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSS 180
Query: 197 SPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPV- 255
+P P P +S P P + + P P+ +S P +P P+
Sbjct: 181 TPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240
Query: 256 -----PALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVS 310
P L P+ S PTL + P ++ P++ P P S P P S P
Sbjct: 241 TRSSTPTLTPS--STPTLTPSNTPTLTPSNTPTLTPSNTPTL--TPSSTPTLTPSSTPTL 296
Query: 311 AP 312
P
Sbjct: 297 TP 298
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 102 bits (255), Expect = 2e-21
Identities = 155/560 (27%), Positives = 213/560 (38%), Gaps = 153/560 (27%)
Query: 143 PLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAP 202
P T + + V P+ V L++ G+ + T AT G PV + PAP
Sbjct: 577 PAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAAT-GEAAPV----------LTVQPAP 625
Query: 203 ICPPAPGSASVPHSV--PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVP---A 257
PPA S +P + P A Q P AP P + P + P PSP LA P
Sbjct: 626 QAPPAV-STPLPLGLQQPQAQQPP---QAPTPQAAAPP---QATTPQPSPGLASSPEKIV 678
Query: 258 LAPAPPSVPTLI--------------------SDSNPLSVSASVLV--PVPASAP----- 290
L P + PT I ++ LSV ASV+V P PA P
Sbjct: 679 LGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATP 738
Query: 291 --------PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA---------PV 333
P P ++PAPAP +P +AP ++ P P S+P+L P
Sbjct: 739 VAKGAGLGPQAPDSQASPAPAP-QIPAAAP----LKGPGPSSSPSLPHQAPLGDSPHLPS 793
Query: 334 PTPVLAPM-PASTPPAAPAPPSVPMPTPTPS-SGPPSTPTLI----------PAFAPTP- 380
P P P P S P + PPS P P P PP+ P + PA P P
Sbjct: 794 PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPT 853
Query: 381 VPAPTPAPI----------FTPAPTPMPAATPAAIPTS--------APIPASFSLSRVCF 422
P P P+ PAP P++T +A+ +S AP P+ F L F
Sbjct: 854 APGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ---F 910
Query: 423 PAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
P +Q P P P T+ +P PPP P T + +T P LP
Sbjct: 911 PPSQGPHKSPTP----PPTLHLVPEPAAPPPPP-----------PRTFQMVTT-PFPALP 954
Query: 483 SYLQDRCL--------PGVLASPELRSYPYAFSVAR---PLTSDSKLVSLEVNRLPCTSP 531
Q + L G++ + P A + PLTS + V + +P
Sbjct: 955 ---QPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQ-----AP 1006
Query: 532 SGSTTTQPAPDGVPGPLADTS---LVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTE 588
SG T T P+ P P+A T L+ A K + P L +S+ P PSG +
Sbjct: 1007 SG-TPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGP---GKPSGLQ 1062
Query: 589 QQTEGTSVTFSPLKSPPQLE 608
+++ S LK PP L+
Sbjct: 1063 YESK-----LSGLKKPPTLQ 1077
Score = 84.3 bits (207), Expect = 9e-16
Identities = 140/519 (26%), Positives = 191/519 (36%), Gaps = 83/519 (15%)
Query: 205 PPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL--VPVQVAT-SVPAPSPPLAPVPALAPA 261
P + G PHS + + + P V L +PV +A S+P S P APA
Sbjct: 523 PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQP-------APA 575
Query: 262 PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPV 321
P+ T++ V +P A A + P L PA + +AP L + AP
Sbjct: 576 GPAATTVLQ---------GVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP- 625
Query: 322 PPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMP---TPTPSSGPPSTPTLI----- 373
AP V P+P + P A PP AP P + P TP PS G S+P I
Sbjct: 626 --QAPPAVSTPLPLGLQQPQ-AQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQP 682
Query: 374 PAFAPTPVPAPTPAPIFTP---APTPMPA-----ATPAAIPTSAPIPASFSLSRVCFPAA 425
P+ PT + +F P + P+ A + PA++ SAP PA PA
Sbjct: 683 PSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQD-------PAP 735
Query: 426 QAPAMQKVPLSFQPGTVLTPSQPLVYIP---PPSCGQPLSVATLPTTLGVSSTLTLPVLP 482
P + L Q P IP P P S +LP + + P LP
Sbjct: 736 ATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS---PHLP 792
Query: 483 SYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPD 542
S R P R SV+RP S+ L + P T P
Sbjct: 793 SPHPTR--------PPSRPPSRPQSVSRP-PSEPPLHPCPPPQAPPTLPGIFVIQNQL-- 841
Query: 543 GVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLK 602
GVP P A TA P +P P G PP P PS T +S T S L
Sbjct: 842 GVPPP-ASNPAPTAPGPPQPPLRPQSQPPEGP-LPPAPHLPPSSTSSAVASSSETSSRLP 899
Query: 603 SPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLT--------PVHTSS 654
+P + ++ PP S+ P + L +P PP P T P
Sbjct: 900 APTPSDFQLQFPP--SQGPHKSPTPPPTLHL-VPEPAAPPPPPPRTFQMVTTPFPALPQP 956
Query: 655 KALL-------STVLSRSQRTTQAAGGNVTSCLGSTSSP 686
KALL S ++ +++ A ++ LG +SP
Sbjct: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSP 995
Score = 72.8 bits (177), Expect = 3e-12
Identities = 134/564 (23%), Positives = 188/564 (33%), Gaps = 111/564 (19%)
Query: 194 TNFSPLPAPICPP----------APGSASV-----PHSVPDAFQVPLSVPAPVPHSGLVP 238
T P PA + PP AP A++ P ++P + P ++
Sbjct: 349 TPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQN 408
Query: 239 VQVATSVPAPS--------PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAP 290
V V + PAP+ PP A P PP + + L+ +S+++P P
Sbjct: 409 V-VLSGFPAPALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLP 467
Query: 291 PSGPVPLSAPAPAPLSVPVSAPPL----ALIQAPVPPSAPTLVLAPVPT----------- 335
L L +SA P ++ A P + L+ P+ T
Sbjct: 468 GQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLG 527
Query: 336 PVLAP--------MPASTPPAAPAPPSVPMPT-------PTPSSGPPSTPTLIPAFAPTP 380
PVLAP + ++ P P MP PT S P+ P
Sbjct: 528 PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVT 587
Query: 381 VPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSF--- 437
+P A + TP PA AA +AP+ PA QAP PL
Sbjct: 588 LPPSAVAMLNTPDGLVQPATPAAATGEAAPV-------LTVQPAPQAPPAVSTPLPLGLQ 640
Query: 438 -----QPGTVLTP---SQPLVYIPPPSCGQPLS----VATLPTTLGVSSTLTLPVLPSYL 485
QP TP + P P PS G S V P + ++ LT L +L
Sbjct: 641 QPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFL 700
Query: 486 -QDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNR---LPCTSPSGSTTTQPAP 541
Q+R + A S P + V+ P + + V + L +P + PAP
Sbjct: 701 PQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAP 760
Query: 542 D-------GVPGPLADTSL----VTASAKVLPTPQPLLP------APSGSSAPP-----H 579
PGP + SL + LP+P P P P S PP H
Sbjct: 761 QIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLH 820
Query: 580 PAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQR 639
P P G V + L PP + P + PL S+ P +
Sbjct: 821 PCPPPQ-APPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQ--------PPEG 871
Query: 640 KTPPMPVLTPVHTSSKALLSTVLS 663
PP P L P TSS S+ S
Sbjct: 872 PLPPAPHLPPSSTSSAVASSSETS 895
Score = 41.6 bits (96), Expect = 0.007
Identities = 192/868 (22%), Positives = 271/868 (31%), Gaps = 201/868 (23%)
Query: 221 FQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAP-----APPSVPTLISDSNPL 275
FQ+P PA G P + + P A P PP+V T + P
Sbjct: 129 FQLPTLQPAD---GGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQ 185
Query: 276 SVSASVLVPVPASAPPS-GPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVP 334
V L P P G V L P P +P +P A +A TL LAP+
Sbjct: 186 DVVNKALSVQPFLQPVGLGNVTLQ-PIPGLQGLPNGSPGGA--------TAATLGLAPIQ 236
Query: 335 T---PVLA-----------PMPASTPPAAPAPPSVPM----------------------- 357
PV+A +P S A+ A PS P+
Sbjct: 237 VVGQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAA 296
Query: 358 -------------------PTPTPSSGPPSTPTLIPAFAPTP-VPAP------TPAPI-- 389
PT TPS P + + P +P VPAP TP PI
Sbjct: 297 VATTLNGNSVFGGAGAASAPTGTPSGQPLA---VAPGLGSSPLVPAPNVILHRTPTPIQP 353
Query: 390 ------------FTPAPTPMPAAT------PAAIPTSAPIPASFSL-------SRVCFPA 424
TP P AT P A+P P + + V
Sbjct: 354 KPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSG 413
Query: 425 AQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLP---VL 481
APA+Q P T + P PP + +P+SV L S++ +P +L
Sbjct: 414 FPAPALQANVFKQPPATTTGAAPPQ---PPGALSKPMSV----HLLNQGSSIVIPAQHML 466
Query: 482 PSYLQDRC--LPGVLASPELRSYPYAFS---------------VARPLTSDSKL---VSL 521
P Q P V +L + P +A P+ ++ L +SL
Sbjct: 467 PGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSL 526
Query: 522 EVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPT---PQPLLPAPS----GS 574
P + + AP V P V+ +A LPT P P PA + G
Sbjct: 527 GPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGV 586
Query: 575 SAPPHPAKM---PSGTEQQTEGTSVT-------------------FSPL---------KS 603
+ PP M P G Q + T +PL +
Sbjct: 587 TLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646
Query: 604 PPQLER-EMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVL 662
PPQ + A+PP+ + S+ +K+ L PP T + T +
Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQ----PPSATPTAILTQDSLQMFLPQ 702
Query: 663 SRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTIPGTYVGVAN 722
RSQ+ A G + L +S V P ++ P+T V L P + A+
Sbjct: 703 ERSQQPLSAEGPH----LSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQ---AS 755
Query: 723 PVPASLLLNKDPNLGLN-RDPRHLPKQEPISIIDQ-GEPKGTGATCGKKGSQAGAEGQPS 780
P PA + P G LP Q P+ P T PS
Sbjct: 756 PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815
Query: 781 TVKRY--TPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTSTQVLPVGWSPYHQ 838
+ P + P LPG + L P +N P +P P
Sbjct: 816 EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
Query: 839 ASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPE 898
A L +S+ + S+ + P S+F S+ H P P P VPE
Sbjct: 876 APHLPPSSTSSAVASSSETSSRLPAPTPSDFQ--LQFPPSQGPHKSP--TPPPTLHLVPE 931
Query: 899 --QDPVTKNKTCRIAAKPYEEQVNPVLL 924
P +T ++ P+ P L
Sbjct: 932 PAAPPPPPPRTFQMVTTPFPALPQPKAL 959
Score = 36.6 bits (83), Expect = 0.22
Identities = 55/195 (28%), Positives = 68/195 (34%), Gaps = 46/195 (23%)
Query: 241 VATSVPAPS---PPLAPVPAL-----APAPPSVPTLISDSNPLSVSASVLVPVPASAPPS 292
+++S P S PP P + A PSV + S+ S S+S A
Sbjct: 1227 LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADED 1286
Query: 293 GPVP-------------------LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPV 333
GP+P L A LS V L + P PP A V P
Sbjct: 1287 GPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPP 1346
Query: 334 PTPVLAPMPAS--------TPPAAP-------AP--PSVPM-PTPTPSSGPPSTPTLIPA 375
P P P P PPAAP AP P +P+ T + G P P PA
Sbjct: 1347 PRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPA 1406
Query: 376 -FAPTPVPAPTPAPI 389
A PAP PA +
Sbjct: 1407 GRARGGSPAPLPAKV 1421
Score = 31.6 bits (70), Expect = 6.9
Identities = 18/55 (32%), Positives = 20/55 (36%)
Query: 342 PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTP 396
P PP PA V P P P PP T + P AP P+ T P
Sbjct: 1329 PVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP 1383
>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
Length = 280
Score = 102 bits (254), Expect = 3e-21
Identities = 74/241 (30%), Positives = 96/241 (39%), Gaps = 16/241 (6%)
Query: 179 LGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVP 238
+GT + P +T + +P P P S P P P P+ P L P
Sbjct: 49 MGTPTLTPSSPPTLTPSNTPTLTPCSTPTLTPCSTPTLTPS--NTPTLTPSSTPT--LTP 104
Query: 239 VQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGP--VP 296
T P+ +P L P P S PTL S P +S P+S P P P
Sbjct: 105 SSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTP 164
Query: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP 356
P+ P P S P L P S P L + PT P+STP P+
Sbjct: 165 TLTPSSTPTLTPSSTPTLT------PSSRPILTRSSTPTLT----PSSTPTLTPSSTPTL 214
Query: 357 MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFS 416
P+ TP+ P STPTL P+ PT P+ P + PT P++TP P+S P S
Sbjct: 215 TPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSS 274
Query: 417 L 417
L
Sbjct: 275 L 275
Score = 101 bits (252), Expect = 5e-21
Identities = 74/237 (31%), Positives = 96/237 (40%), Gaps = 17/237 (7%)
Query: 218 PDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSV 277
P P P+ P L P T P +P L P P + PTL S P
Sbjct: 46 PREMGTPTLTPSSPPT--LTPSNTPTLTPCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLT 103
Query: 278 SASVLVPVPASAPPSGP--VPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPT 335
+S P+S P P P P+ P P S P L P + T L P T
Sbjct: 104 PSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSST 163
Query: 336 PVLAPM------PASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPI 389
P L P P+STP P+ + + TP+ P STPTL P+ PT P+ TP I
Sbjct: 164 PTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLI 223
Query: 390 FTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPS 446
+ PT P++TP P+S P +L+R P + + S P LTPS
Sbjct: 224 PSSTPTLTPSSTPTLTPSSRP-----TLTRSSTPTLTPSSTPTLTPSSTP--TLTPS 273
Score = 84.7 bits (208), Expect = 7e-16
Identities = 76/228 (33%), Positives = 93/228 (40%), Gaps = 22/228 (9%)
Query: 264 SVPTLISDSNPLSVSASVLVPV-PASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVP 322
SV + P + L P P + PS P P P P S P L P
Sbjct: 36 SVGEMTGPYGPREMGTPTLTPSSPPTLTPSN-TPTLTPCSTPTLTPCSTPTLTPSNTPTL 94
Query: 323 PSAPTLVLAPVPTPVLAP--MPASTPPAAPAPPSVPMPTPTPSSGP----PSTPTLIPAF 376
+ T L P TP L P P TP + P PT TPSS P STPTL P+
Sbjct: 95 TPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPSS 154
Query: 377 APTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLS 436
PT P+ TP + PT P++TP P+S PI L+R P + + S
Sbjct: 155 TPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI-----LTRSSTPTLTPSSTPTLTPS 209
Query: 437 FQPGTVLTPSQPLVYIP------PPSCGQPLSVATLPTTLGVSSTLTL 478
P LTPS IP PS L+ ++ P TL SST TL
Sbjct: 210 STP--TLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRP-TLTRSSTPTL 254
Score = 75.1 bits (183), Expect = 5e-13
Identities = 80/280 (28%), Positives = 107/280 (38%), Gaps = 64/280 (22%)
Query: 322 PPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPV 381
P S PTL P TP L P STP P P+ TP+ P STPTL P+ PT
Sbjct: 56 PSSPPTLT--PSNTPTLTP--CSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLT 111
Query: 382 PAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT 441
P+ TP + PT P++TP P+S P +L+R P
Sbjct: 112 PSSTPTLTPSSTPTLTPSSTPTLTPSSTP-----TLTRSSTPT----------------- 149
Query: 442 VLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRS 501
LTPS P + TL SST TL PS S
Sbjct: 150 -LTPSSTPTLTPSST-----------PTLTPSSTPTLT--PS-----------------S 178
Query: 502 YPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVL 561
P +RP+ + S +L + P +PS + T P+ P + +L +S L
Sbjct: 179 TPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTL 238
Query: 562 -PTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSP 600
P+ +P L S P PS T T ++ T +P
Sbjct: 239 TPSSRPTLTRSS------TPTLTPSSTPTLTPSSTPTLTP 272
Score = 69.7 bits (169), Expect = 2e-11
Identities = 59/212 (27%), Positives = 80/212 (37%), Gaps = 28/212 (13%)
Query: 172 NTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPV 231
NT L T + P +T + +P P P +S P P + P
Sbjct: 90 NTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPT 149
Query: 232 PHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPP 291
P +S P +P + P L P+ S PTL S P+ +S
Sbjct: 150 LTPSSTPTLTPSSTPTLTP--SSTPTLTPS--STPTLTPSSRPILTRSS----------- 194
Query: 292 SGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPA 351
P P+ P P S P L P + PTL+ P TP L P+STP P+
Sbjct: 195 ---TPTLTPSSTPTLTPSSTPTL------TPSNTPTLI--PSSTPTLT--PSSTPTLTPS 241
Query: 352 PPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA 383
+ TP+ P STPTL P+ PT P+
Sbjct: 242 SRPTLTRSSTPTLTPSSTPTLTPSSTPTLTPS 273
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 102 bits (254), Expect = 3e-21
Identities = 118/408 (28%), Positives = 162/408 (39%), Gaps = 70/408 (17%)
Query: 176 LATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHS-VPDAFQVPLSVPAPVPHS 234
L T+ + P+VT P P P PPA + P S +P + P + P PVP
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS---PPTPPVPVPPP 838
Query: 235 GLVPVQVATSVPAPSPPLAPVPALA-------PAPPSVPTLISDSNPLSVSASVLVPVPA 287
L Q + P PS PL+PVP++ P PP+ P + +S PL PVPA
Sbjct: 839 TLPKQQSFCAKPPPS-PLSPVPSVVKQIASQFPPPPTPPAM--ESQPLK-------PVPA 888
Query: 288 S-APPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTP 346
+ AP S P + P P S+PV +P P PP + + P P+PV AP P P
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDF----PPPPPESSLVFPPPPPSPVPAPPPPPPP 944
Query: 347 PAAPAPPSVPMP----TPTPSSG---PPSTP---TLIPAFAPTPVPAPTPAPI------F 390
A+P P P + T S G PP TP + I + + P P + F
Sbjct: 945 TASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKF 1004
Query: 391 T-PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAA--QAPAMQKVPLSFQPG---TVLT 444
T PA + P+ P + P P +LS V P Q K P+ G V
Sbjct: 1005 TPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEF 1064
Query: 445 PSQPL---VYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRS 501
PS P PPP PL +P +++ + V+ Q V +P
Sbjct: 1065 PSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAP---- 1120
Query: 502 YPYAFSVARPLTSDS-KLVSLEVNRLPC---------TSPSGSTTTQP 539
RP +DS +L E++ P TSP S + QP
Sbjct: 1121 -----PPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163
Score = 99.8 bits (247), Expect = 2e-20
Identities = 122/438 (27%), Positives = 156/438 (35%), Gaps = 55/438 (12%)
Query: 223 VPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSA--- 279
VP P P + Q + +P P PP P P P PP P L S S P + SA
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPP--PPPPPPPPPPPPPPLPSQSAPSAGSAAPM 663
Query: 280 ----SVLVPVPASAPPSGPV--PLSAPAPAPLSV--PVSAPPLALIQAPVPPSAPTLVLA 331
S + + ++ SG + P + P SV + PP ++ P PP P
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP----- 718
Query: 332 PVPTPVLAPMPASTPPAAPAPPSVPMPTP---------TPSSGPPSTPTLIPAFAPTPVP 382
PTP A P AP+ P P P PP+ P P AP P
Sbjct: 719 --PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776
Query: 383 APTPAPIFT-PAPTP----MPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSF 437
AP P P+ T PAPT P T AA PT P P + + FPA+ P P
Sbjct: 777 AP-PKPLVTIPAPTSTKTVAPVVTQAAPPTPTP-PVPPAKKQPAFPASYIPPSPPTPPVP 834
Query: 438 QPGTVLTPSQPLVYIPPPSCGQPL--------SVATLPTTLGVSSTLTLPVLPSYLQDRC 489
P L Q PPPS P+ S P T + L +P+ + +
Sbjct: 835 VPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894
Query: 490 LPGVLASPELR--SYPYAFSVARPLTSDSKLV--SLEVNRLPCTSPSGSTTTQPAPD--G 543
P V A P+ + S P P +S LV + +P P T P PD G
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 544 VPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKS 603
PG + K PTPQ S S A K PS + F+P
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPS-----VDSLVSKFTPPAE 1009
Query: 604 PPQLEREMASPPECSEMP 621
+E PP P
Sbjct: 1010 SGSPSKETLPPPAAPPKP 1027
Score = 99.8 bits (247), Expect = 2e-20
Identities = 103/342 (30%), Positives = 134/342 (39%), Gaps = 70/342 (20%)
Query: 183 VPVEGTLPLVTTNFSPLPAPICPPAPGSASVP-HSVPDAFQVPLSVPAPVPHSGLVPVQV 241
VP G +P P P P PP PGSA P A +P AP P + VQ
Sbjct: 703 VPPNGVVP-------PPPPPPPPPTPGSAMAQLKPAPCAPSLP-QFSAPPPPLKIHQVQH 754
Query: 242 ATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPA 301
T V P+PP P P AP PP P + P S + PV A P P P PA
Sbjct: 755 ITQVAPPTPP-PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPA 813
Query: 302 ------------PAPLSVPVSAPPLALIQ-----APVPPS----APTLV------LAPVP 334
P+P + PV PP L + A PPS P++V P P
Sbjct: 814 KKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP 873
Query: 335 TPV------LAPMPASTPPAAPA---------PPSVPMPTPTPSSGPPSTPTLIPAFAPT 379
TP L P+PA+ P +P P S+P+P+P PP + + P
Sbjct: 874 TPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP---- 929
Query: 380 PVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQP 439
P P+P PA P P P P A+P + +P + S +P +K P + Q
Sbjct: 930 PPPSPVPA----PPPPPPPTASPTPDKSGSPGKKTSKTS--------SPGGKKPPPTPQR 977
Query: 440 GTVLTPSQPLVYIPP--PSCGQPLSVATLPTTLGVSSTLTLP 479
+ + S + P PS +S T P G S TLP
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLP 1019
Score = 69.7 bits (169), Expect = 2e-11
Identities = 86/342 (25%), Positives = 127/342 (37%), Gaps = 57/342 (16%)
Query: 340 PMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPA 399
P + PP +P P V TP +S P P P P P P P P P P P+P+
Sbjct: 601 PYTSLVPPLSPQPKIV---TPYTASQPS------PPLPPPPPPPPPPPPPPPPPPPPLPS 651
Query: 400 ATPAAIPTSAPIPASFS-LSRVCFPAAQAPAMQKVPLSFQPGTVLTPS-QPLVYIPPPSC 457
+ + ++AP+ +S ++R+ + + A+ K P P + + S +P + +PP
Sbjct: 652 QSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP---TPPVMQSQSVKPQILVPPNGV 708
Query: 458 GQPLSVATLPTTLG--VSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSD 515
P P T G ++ P PS Q P L ++ + VA P
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL---KIHQVQHITQVAPPTPPP 765
Query: 516 SKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTP-------QPLL 568
+ LP +P T PAP +VT +A PTP QP
Sbjct: 766 PPPIPAP---LPPQAPPKPLVTIPAPTSTK---TVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 569 PA---PSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMAS-------PPECS 618
PA P PP P P+ +QQ+ SPL P + +++AS PP
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 619 EMPL---------------DLSSKSNRQKLPLPNQRKTPPMP 645
PL K +P+P+ PP P
Sbjct: 880 SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPP 921
Score = 68.6 bits (166), Expect = 5e-11
Identities = 97/387 (25%), Positives = 132/387 (34%), Gaps = 79/387 (20%)
Query: 321 VPPSAP-----TLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPA 375
VPP +P T A P+P L P P PP P PP P P P PS PS + P
Sbjct: 606 VPPLSPQPKIVTPYTASQPSPPLPPPPPPPPP--PPPPPPPPPPPLPSQSAPSAGSAAPM 663
Query: 376 FA---------------------PTPVPAPT----------PAPIFTPAPTPMPAATP-A 403
F PTP + P + P P P P TP +
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Query: 404 AIPTSAPIPASFSLSRVCFPAAQAP-AMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLS 462
A+ P P + SL + F A P + +V Q P P + P P P
Sbjct: 724 AMAQLKPAPCAPSLPQ--FSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKP 781
Query: 463 VATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLE 522
+ T+P S+ PV+ P V + + ++P ++ P T
Sbjct: 782 LVTIPAP--TSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTP-------P 832
Query: 523 VNRLPCTSPSGSTTTQPAPDGVPGPLADT-SLVTASAKVLPTP--------QPLLPAPSG 573
V P T P + P P PL+ S+V A P P QPL P P+
Sbjct: 833 VPVPPPTLPKQQSFCAKPP---PSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPA- 888
Query: 574 SSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL----------- 622
+ AP P + + + Q V PP + PP S +P
Sbjct: 889 NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASP 948
Query: 623 --DLSSKSNRQ--KLPLPNQRKTPPMP 645
D S ++ K P +K PP P
Sbjct: 949 TPDKSGSPGKKTSKTSSPGGKKPPPTP 975
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 100 bits (248), Expect = 2e-20
Identities = 175/621 (28%), Positives = 227/621 (36%), Gaps = 146/621 (23%)
Query: 190 PLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249
PLV +P A + PP GSA VP A V P P P P A
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG-PEPAPAGPAKPAGPAALAARAG 171
Query: 250 PPLAPVPALAPAP-PSVPTLISDSNPLSVSASVLVPVPASAPP-----SGPVPL-SAPAP 302
P P P P P P P + L+ SA++L A+AP +GP L P P
Sbjct: 172 PGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
Query: 303 APLSVPVSAPPLALIQAPVPPSAPTLVLAPVP-TPVLAPMPASTPPAAPA----PPSVPM 357
A + PP AP P+AP+ AP P P AP P PP APA PP P
Sbjct: 232 AAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPP---PPPAPATLARPPGHPA 288
Query: 358 --PTPTPSSGPPSTPTLIPAFAPTPVPAPT----------PAP-IFTPAPTP-------- 396
PT P+ PP+ + P PAP P P AP P
Sbjct: 289 GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348
Query: 397 --MPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPP 454
+ AA PAA +A PAS + S V P Q P + P TP+ +P
Sbjct: 349 RVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPS--PAAVPPPAPGTPTG----LPK 402
Query: 455 PSCG---QPLSVATLPTTLGVSSTLTLPVL----------PSYLQDRCLP---------- 491
+ G Q LS TT G+ +TLT VL P+ +Q+ LP
Sbjct: 403 GAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSEN 462
Query: 492 --------GVLASPELRSY--PYAFSVARPLT-SDSKLVSLEVNRLPCTS---------- 530
LA + +++ P RP T + + V + + P T
Sbjct: 463 GQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTT 522
Query: 531 -----PSGSTTTQPA----------PDGVPGPLADT-SLVTASAKVLPTPQPLLP-APSG 573
TT QP+ P V G A T SL TA+A TPQ +P A +
Sbjct: 523 IIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTT 582
Query: 574 SSAPPHP--------------AKMPSGTEQQTEGTSVTFSPLKS------------PPQL 607
SSA K+ S +Q TE T+ L +L
Sbjct: 583 SSAATETMENVKKCKNFLSTLIKLASSGKQSTE-TAANVKELVQNLLDGKIEAEDFTSRL 641
Query: 608 EREMASPPECSEMP-LDLSSKSNRQKLP------LPNQRKTPPMPVLTPVHTSSKALLST 660
RE+ S P+ +P L S + RQ P +Q++ PP P ++ AL +
Sbjct: 642 YRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPP-----PTSQATTALTAV 696
Query: 661 VLSRS-QRTTQAAGGNVTSCL 680
VLS S QRT VTS L
Sbjct: 697 VLSSSVQRTAGKTAATVTSAL 717
Score = 81.6 bits (200), Expect = 6e-15
Identities = 129/531 (24%), Positives = 180/531 (33%), Gaps = 86/531 (16%)
Query: 207 APGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVP 266
+P A+ A P + P P P P P P P P+ PAPP+
Sbjct: 66 SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125
Query: 267 TLISDSNPLSVSASVLVPVPASAP-PSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSA 325
P SA PVPA+A +GP PAPA + P LA P P
Sbjct: 126 L----RPPPEGSAGSCAPVPAAAAVAAGP----EPAPAGPAKPAGPAALAARAGPGPGPG 177
Query: 326 PTLVLAPVPTPVLAPMPAST-----------PPAAPA------PPSVPMPTPTPSSGPPS 368
P P P P A T AAPA P+ +P P P++ P
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA--PG 235
Query: 369 TPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSL--SRVCFPAAQ 426
T P F P AP +P P PAA AA P P PA+ + P
Sbjct: 236 TVIQTPPFVGAAAPPAPAAP--SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293
Query: 427 APAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQ 486
APA+ P + Q G S P P+ G P V+ P G + P
Sbjct: 294 APAVPP-PAAAQNG----GSAGAAPAPAPAAGGPAGVSGQP---GPGAAAAAPA------ 339
Query: 487 DRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPG 546
PGV A R A A+ L + + P+ + + + G
Sbjct: 340 ----PGVKAESPKRVVQAAPPAAQTLAA--------------SGPASTAASMVIGPTMQG 381
Query: 547 PLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQ 606
L + V A PT LP + + ++ P+ T T G T +P P+
Sbjct: 382 ALPSPAAVPPPAPGTPTG---LPKGAAGAVTQSLSRTPTAT---TSGIRATLTPTVLAPR 435
Query: 607 LEREMASPPECSEMPLD----LSSKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVL 662
L + +P L L N Q L +P Q L + + A T +
Sbjct: 436 LPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQ-------ALAQMQAQAHAQPQTTM 488
Query: 663 SRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKNSTALISTI 713
+ T +A S + + +P I R P+T +K + +T+
Sbjct: 489 APRPATPTSAPPVQISTVQAPGTPI-----IARQVTPTTIIKQVSQAQTTV 534
Score = 67.0 bits (162), Expect = 1e-10
Identities = 132/570 (23%), Positives = 189/570 (33%), Gaps = 65/570 (11%)
Query: 291 PSGPVPLSAPAPAPLSVPVSAPPLALIQA-PVPPSAPTLVLAPVPTPVLAPMPASTPPAA 349
P P +A A A + VS P A P P+ AP P P P P
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
Query: 350 PAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPA-PTPMPA-----ATPA 403
P PPS P PP+ P AP PA A P P PA A PA
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
Query: 404 AI---------PTSAPIPASFSLSRVCFPAAQ----APAMQKVPLSFQPGTVLTPSQPLV 450
A+ P P P AAQ + A+ + P L + P
Sbjct: 165 ALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224
Query: 451 YIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVAR 510
+P P P +V P +G ++ P P+ SP P A + A
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAA----PPAPA----------APSPPAAPAPAAPAAAP 270
Query: 511 PLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPA 570
P + P P+G T PA VP P A + SA P P P
Sbjct: 271 PPPPPAPATLAR----PPGHPAGPPTAAPA---VPPPAAAQN--GGSAGAAPAPAPAAGG 321
Query: 571 PSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNR 630
P+G S P P + + S +PP + AS P + + +
Sbjct: 322 PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGP---T 378
Query: 631 QKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIF 690
+ LP+ PP TP A + S S+ T TS + +T +P V+
Sbjct: 379 MQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTA-----TTSGIRATLTPTVLA 433
Query: 691 PEIVRNGDPSTWVKN-----STALISTIPGTYVGVANPVPASL--LLNKDPNLGLNRDPR 743
P + + T ++N L+ + G + + A + + P + P
Sbjct: 434 PRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA 493
Query: 744 HLPKQEPISIIDQGEP-------KGTGATCGKKGSQAGAEGQPSTVKRYTPARIAPGLPG 796
P+ I P + T T K+ SQA QPS + +P + G
Sbjct: 494 TPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLG 553
Query: 797 CQTKELSLWKPTGPANIYPRCSVNGKPTST 826
+ SL T P+ +V G T++
Sbjct: 554 GAAQTASLGTATAVQTGTPQRTVPGATTTS 583
Score = 58.2 bits (139), Expect = 7e-08
Identities = 130/560 (23%), Positives = 190/560 (33%), Gaps = 114/560 (20%)
Query: 198 PLPAPICPPAPGSASVPHSVPDAFQVPLSV---------PAPVPHSGLVPVQVA------ 242
P PA + P PG + P + A P + PAP P +G P V+
Sbjct: 275 PAPATLARP-PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG-GPAGVSGQPGPG 332
Query: 243 TSVPAPSPPL---APVPALAPAPPSVPTLISDSNPLSVSASVLV--------PVPASAPP 291
+ AP+P + +P + APP+ TL + S P S +AS+++ P PA+ PP
Sbjct: 333 AAAAAPAPGVKAESPKRVVQAAPPAAQTLAA-SGPASTAASMVIGPTMQGALPSPAAVPP 391
Query: 292 SGP-VPLSAPAPAPLSVPVS----------------APPLALIQAPVPPSAPTLV----- 329
P P P A +V S P + + P PP PT +
Sbjct: 392 PAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQL 451
Query: 330 -------------LAPVPTPVLAPM-------PASTPPAAPAPPSVPMPTPTPSSGPPST 369
L +P LA M P +T PA P+ P + P T
Sbjct: 452 PPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGT 511
Query: 370 PTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPA 429
P + PT + T P+ +P P A+ + S A Q
Sbjct: 512 PIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGT 571
Query: 430 MQKVPLSFQPGTVLTPSQPLVYIP-PPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDR 488
Q+ PG T S + C LS + G ST T + +Q+
Sbjct: 572 PQRT----VPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQN- 626
Query: 489 CLPGVLASP--------ELRSYPYAFSV---------ARPLTSDSKLVSLEVNRLPCTSP 531
L G + + EL S P + V R LT DS + + P
Sbjct: 627 LLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQQQPPPPT 686
Query: 532 SGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQT 591
S +TT A + +S+ + K T L P S P G +Q
Sbjct: 687 SQATTALTA------VVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQV----GVGKQG 736
Query: 592 EGTSVTFSPLKSPPQLEREMASPPE--CSEMPL-DLSSKSNRQKLPLPNQ---RKTPPMP 645
+ T + P L R PP+ ++ P+ L NR L P Q P+P
Sbjct: 737 QPTPLVIQQPPKPGALIR----PPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPLQPVP 792
Query: 646 VLTPVHTSSKALLSTVLSRS 665
V+ P LS V +++
Sbjct: 793 VVKPAVLPGTKALSAVSAQA 812
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 97.8 bits (242), Expect = 8e-20
Identities = 110/429 (25%), Positives = 149/429 (34%), Gaps = 56/429 (13%)
Query: 184 PVEGTLPLVTTNFSPLPAPICPPAPGS-ASVPHSV----PDAFQVPLSVPAP----VPHS 234
P +P +T SP P P P S S P V P + QVP S P P+S
Sbjct: 1074 PDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYS 1133
Query: 235 GLVPVQVATSVPAPSP--PLAPVPALAPAP------------PSVPTLISDSNPLSVSAS 280
V + P+PSP P P +AP P P+ P + +P +++ S
Sbjct: 1134 STVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHS 1193
Query: 281 VLVPVPASAPPSG---------PVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLA 331
++P P + P P P + P P P + P P T+ +
Sbjct: 1194 TMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHS 1253
Query: 332 P-VPTPVLAPMPAST--PPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAP 388
+P P P P +T P P P + P PT TP PT P TP P TP P
Sbjct: 1254 TMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYP 1313
Query: 389 IFTPAP-------TPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT 441
TP P TP P++TP S P LS P++ P
Sbjct: 1314 TTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAP 1373
Query: 442 VLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRS 501
+ SQ P P+ S ++ T++ ST + P SP L
Sbjct: 1374 HTSTSQIPTLEPSPALESSPSRSSTATSMDPLST-----------EDFKPPRSQSPNLTP 1422
Query: 502 YP--YAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAK 559
P S + S L+S + L P T P P PGP T +
Sbjct: 1423 PPTHTPHSASDLTVSPDPLLSPTAHPLD-HPPLDPLTLGPTPGQSPGPHGPCVAPTPPVR 1481
Query: 560 VLPTPQPLL 568
V+ P L
Sbjct: 1482 VMACEPPAL 1490
Score = 95.9 bits (237), Expect = 3e-19
Identities = 137/537 (25%), Positives = 192/537 (35%), Gaps = 80/537 (14%)
Query: 190 PLVTTNFSPLPAP-----ICPPAPGSAS------VPHSV---------PDAFQVPLSVPA 229
P T P P+P PP P S PHS PD S P
Sbjct: 997 PAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDT-----SPPT 1051
Query: 230 PVPHSGLVPVQVATS--VPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPA 287
P P S P + TS +P + VPAL P P P L + L+ S V +
Sbjct: 1052 PDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTP-LPTLPKELTSDPSTPSEVTS 1110
Query: 288 SAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPP 347
+P S VP S P + P S+ ++P P +P P PT P+ P
Sbjct: 1111 LSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPT 1170
Query: 348 AAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPT-------PAPIFTPAP--TPMP 398
P P+ P PT TP + T+IP TP P T P P TP P T P
Sbjct: 1171 VTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQP 1230
Query: 399 AATPAAI---PTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPP 455
TP + PT+ P P + + S + P QP T + P+ +P P
Sbjct: 1231 TTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTP---------QPFTTMQPTT----MPHP 1277
Query: 456 SCGQPLSVATLPTTLGVSSTLTLPVL---------PSYLQDRCLPGVLASPELRSYPYAF 506
+ + PTT +T P + P+ D +P+ S P
Sbjct: 1278 TTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVIT 1337
Query: 507 SVARPLTSDSKLVSLEV---------NRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTAS 557
+V+ P + ++L S + +L T+P+ T+T P P P ++S +S
Sbjct: 1338 TVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSS 1397
Query: 558 AKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPEC 617
P S P+ P+ T +V+ PL SP + PP
Sbjct: 1398 TATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSP--TAHPLDHPP-- 1453
Query: 618 SEMPLDLSSKSNRQKLPL-PNQRKTPPMPVLT---PVHTSSKALLSTVLSRSQRTTQ 670
PL L + P P TPP+ V+ P A + V + QR TQ
Sbjct: 1454 -LDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVRDVGGQLQRLTQ 1509
Score = 70.1 bits (170), Expect = 2e-11
Identities = 72/246 (29%), Positives = 92/246 (37%), Gaps = 29/246 (11%)
Query: 178 TLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAP--VPHSG 235
T T +P T P T P P P + PH P + P P PH
Sbjct: 1251 THSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPH--------PTTTPHPTTTPHPT 1302
Query: 236 LVPVQVATSVP--APSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPA-SAPPS 292
+ P T P P P P P P P S P + + S P S+ + P A + PS
Sbjct: 1303 MTPDPTTTPYPTTTPDPTTTPHPT-TPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPS 1361
Query: 293 GPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPM-PAST----PP 347
L+ APAP + + Q P +P L +P + M P ST PP
Sbjct: 1362 LHPQLTFTAPAPHT--------STSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPP 1413
Query: 348 AAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAP-TPAPIFTPAPTPMPAATPAAIP 406
+ +P P PT TP S T + P +PT P P T PTP + P P
Sbjct: 1414 RSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHG-P 1472
Query: 407 TSAPIP 412
AP P
Sbjct: 1473 CVAPTP 1478
Score = 58.5 bits (140), Expect = 5e-08
Identities = 91/346 (26%), Positives = 129/346 (37%), Gaps = 61/346 (17%)
Query: 340 PMPASTPPAAPAPPSVPMPTPTPSSGPP-------STPTLIPAFAPTPVPAPTPAPIFTP 392
P PA+T A P P P P+ S GPP S+ L P A T A + AP +P
Sbjct: 995 PRPAATRTA----PPTPSPGPSASPGPPGPALTSDSSRELTPHSALTS-EATSDAPDTSP 1049
Query: 393 APTPMPAA--TPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVP-LSFQPGTVLTPSQPL 449
PTP PA+ P I TS F+LS P VP L+ +P P+ P
Sbjct: 1050 -PTPDPASRTNPDLILTS----PDFALS--------TPDSSVVPALTPEPSPTPLPTLPK 1096
Query: 450 VYIPPPSCGQPLSVATL-PTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSV 508
PS P V +L PT+ V + T P L + + SP+ P+ +
Sbjct: 1097 ELTSDPS--TPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTT 1154
Query: 509 ARPLTSDSKLVSLE--------VNRLPCTSPSGSTTTQ----PAPDGVPGPLADTSLVTA 556
P + + +L P T+P +T T P P P P + T
Sbjct: 1155 PDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTM 1214
Query: 557 SAKVLPTPQP---LLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMAS 613
TPQP + P + S PHP P T++T S + P + +
Sbjct: 1215 IPDPTTTPQPFTTMQPTTTPHSTTPHPTTTP-------HPTTITHSTMIPDPTTTPQPFT 1267
Query: 614 PPECSEMPLDLSSKSNRQKLPLPNQRKTP-----PMPVLTPVHTSS 654
+ + MP + P+ TP P P +TP T++
Sbjct: 1268 TMQPTTMP---HPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTT 1310
Score = 57.0 bits (136), Expect = 2e-07
Identities = 71/274 (25%), Positives = 99/274 (36%), Gaps = 40/274 (14%)
Query: 347 PAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAA-- 404
P +P V T +P P PA T P P+P P +P P P PA T +
Sbjct: 970 PGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGP-PGPALTSDSSR 1028
Query: 405 --IPTSAPIPASFSLSRVCFPAAQAPAMQKVP---LSFQPGTVLTPSQPLV--YIPPPSC 457
P SA + S + P PA + P L+ + TP +V P PS
Sbjct: 1029 ELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPS- 1087
Query: 458 GQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSK 517
P + TLP L + V +P +P+L + PY+ +V+
Sbjct: 1088 --PTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVS-------- 1137
Query: 518 LVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAP 577
E +R P SPS TT P P P P+ + PT P P +
Sbjct: 1138 ----EYSRSPDPSPSPHPTTTPDPTMAPDPITTLN---------PTVTPHFPTTPHPTTT 1184
Query: 578 PHP------AKMPSGTEQQTEGTSVTFSPLKSPP 605
PHP +P T T++T S + P
Sbjct: 1185 PHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDP 1218
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 96.7 bits (239), Expect = 2e-19
Identities = 65/171 (38%), Positives = 76/171 (44%), Gaps = 21/171 (12%)
Query: 246 PAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPL 305
P P PP P P PAPP P L+S+++P P+P P P AP P P
Sbjct: 24 PEPPPPWPPPPP-PPAPPPAPPLLSEASP--------EPIPE------PCPELAPGPCPE 68
Query: 306 SVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAP----PSVPMPTPT 361
+ SA L P P + P AP P AP PA+ P PAP S P PTP
Sbjct: 69 ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPE 128
Query: 362 PS--SGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAP 410
P+ S P P L P AP P PTP P+ AP P A P P+ AP
Sbjct: 129 PALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179
Score = 88.6 bits (218), Expect = 5e-17
Identities = 69/232 (29%), Positives = 82/232 (35%), Gaps = 39/232 (16%)
Query: 177 ATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGL 236
A GT P +G P SP P P PP P PAP P L
Sbjct: 7 AAQGTAPPQDGEQPAE----SPEPPPPWPPPPPP-----------------PAPPPAPPL 45
Query: 237 VPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVP 296
+ +P P P LAP P S L ++ P + P P A P P
Sbjct: 46 LSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEP 105
Query: 297 LSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP 356
+ PAP P AP A AP P P L P P P L TP AP P
Sbjct: 106 ATEPAPEP------APEPATESAPEPTPEPALESVPEPAPEL------TPEVAPELAPEP 153
Query: 357 MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFT------PAPTPMPAATP 402
P P P P P F P+P P P+ T +P+P P+ +P
Sbjct: 154 TPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPSPSP 205
Score = 77.4 bits (189), Expect = 1e-13
Identities = 60/183 (32%), Positives = 72/183 (39%), Gaps = 9/183 (4%)
Query: 284 PVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPA 343
P P APP P LS +P P +P P LA P S L PTP A PA
Sbjct: 33 PPPPPAPPPAPPLLSEASPEP--IPEPCPELAPGPCPEATSESATELYTEPTPEPATEPA 90
Query: 344 STPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPA----PTPAPIFTPAPTPMPA 399
S P PA P P P+ P P A PTP PA P PAP TP P A
Sbjct: 91 SEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELA 150
Query: 400 ATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPSCGQ 459
P P + P + F + AP + + P+ + + T P P PS
Sbjct: 151 PEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSP---SPSPSPRT 207
Query: 460 PLS 462
P+S
Sbjct: 208 PMS 210
Score = 41.6 bits (96), Expect = 0.007
Identities = 57/219 (26%), Positives = 78/219 (35%), Gaps = 39/219 (17%)
Query: 339 APMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPA------FAPTPVP------APTP 386
A + PP P+ P P PP P PA +P P+P AP P
Sbjct: 6 AAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGP 65
Query: 387 APIFT--------PAPTPMPAATPAAIPTSAPI--PASFSLSRVCFPAAQAPAMQKVPLS 436
P T PTP PA PA+ P P PA + A PA + P
Sbjct: 66 CPEATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAP-- 123
Query: 437 FQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLAS 496
+P TP L +P P+ VA +T + P + + A+
Sbjct: 124 -EP----TPEPALESVPEPAPELTPEVAPELAPEPTPEPVT-ELAPEFCPE-------AA 170
Query: 497 PELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGST 535
PE R P + P+ D++ L+ + P SPS T
Sbjct: 171 PEFRPSPAPCLLQCPV--DTRERGLKTSPSPSPSPSPRT 207
Score = 39.3 bits (90), Expect = 0.033
Identities = 49/207 (23%), Positives = 77/207 (37%), Gaps = 24/207 (11%)
Query: 444 TPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYP 503
+P P + PPP P + P L +S +P L P A+ E +
Sbjct: 23 SPEPPPPWPPPPP---PPAPPPAPPLLSEASPEPIPEPCPELAPGPCPE--ATSESATEL 77
Query: 504 YAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPT 563
Y P T + + E P T P+ T+PAP+ P P +++ PT
Sbjct: 78 YTEPTPEPATEPASEPAPE----PATEPAPEPATEPAPEPAPEPATESA-------PEPT 126
Query: 564 PQPLL---PAPSGSSAPP-HPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSE 619
P+P L P P+ P P P T + + F P +P E + P +
Sbjct: 127 PEPALESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAP---EFRPSPAPCLLQ 183
Query: 620 MPLDLSSKSNRQKLPLPNQRKTPPMPV 646
P+D + + P P+ +P P+
Sbjct: 184 CPVDTRERGLKTS-PSPSPSPSPRTPM 209
Score = 34.3 bits (77), Expect = 1.1
Identities = 37/129 (28%), Positives = 47/129 (36%), Gaps = 11/129 (8%)
Query: 527 PCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSG 586
P SP P P P A L AS + +P P P L + P A S
Sbjct: 20 PAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPEL-----APGPCPEATSESA 74
Query: 587 TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL-----DLSSKSNRQKLPLPNQRKT 641
TE TE T + S P E PE + P + +++S + P P
Sbjct: 75 TELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESV 134
Query: 642 P-PMPVLTP 649
P P P LTP
Sbjct: 135 PEPAPELTP 143
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 96.3 bits (238), Expect = 2e-19
Identities = 118/436 (27%), Positives = 174/436 (39%), Gaps = 52/436 (11%)
Query: 186 EGTLPLVTTNFSPLPAPICPPA---PGSASVPHSVPD----AFQVPLSVPAPVPHSGLVP 238
EGT + + AP A G ++V P+ A VP++ P P
Sbjct: 918 EGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEG---P 974
Query: 239 VQVATSVPAPSPP-LAPVPALAPAPPSVPTLI--SDSNPLSVSASVLVPVPASAPPSGPV 295
V AT+V AP P A V P P+ P + P S +A+V P ++P +
Sbjct: 975 VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034
Query: 296 PLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSV 355
P P +VP P + A P PT A VPTP PA+ P P S
Sbjct: 1035 PPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1094
Query: 356 PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTP-MPAATPAAIPTSAPIPAS 414
PTP PT A PTP +PA PTP PA+ AA+PT P +
Sbjct: 1095 AAAVPTPEE-----PTSPAAAVPTPEEPASPA---AAVPTPEEPASPAAAVPT--PEEPA 1144
Query: 415 FSLSRVCFPAAQAPAMQKVPL---SFQP-GTVLTPSQPLVYIP-PPSCGQPLS-VATLPT 468
F V P A A VP S P V TP++ + + +P S A++PT
Sbjct: 1145 FPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204
Query: 469 TLGVSSTL---TLPV--LPSYLQDRCLPGVLASPELRSYPYAF--SVARPLTSDSKLVSL 521
+ +TL T P +P+ + L +++PE + P A ++ P +S + +++
Sbjct: 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264
Query: 522 EVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQ-----------PLLPA 570
E +SP+ S T P +++ + A +PTP+ P +PA
Sbjct: 1265 E----ELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPA 1320
Query: 571 PSGSSAPPHPAKMPSG 586
++ PP P G
Sbjct: 1321 IPAAAVPPMEEVSPIG 1336
Score = 76.6 bits (187), Expect = 2e-13
Identities = 104/390 (26%), Positives = 148/390 (37%), Gaps = 66/390 (16%)
Query: 193 TTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPL 252
T+ + +P P P +P +A P P + + P P P + P+ P
Sbjct: 1014 TSPAAAVPTPEEPTSPAAAVPPPEEPTS----PAAAVPTPEEPTSPAAAVPTPEEPTSPA 1069
Query: 253 APVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAP 312
A VP P P+ P + S + VP P P+ P +A P P A
Sbjct: 1070 AAVP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEE--PTSP---AAAVPTP---EEPAS 1119
Query: 313 PLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP-PSTPT 371
P A + P P++P + P P P PA P A +V +PTP S+ P + PT
Sbjct: 1120 PAAAVPTPEEPASPAAAV-PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT 1178
Query: 372 LIPAFAPTPVPAPTPAPIFTPAPTPMPAA---------TPAAIPTSAPIPASFSLS---- 418
+ + V A P A P PAA +PAA ++ PAS + +
Sbjct: 1179 PAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNP 1238
Query: 419 -RVCFPAAQAPAMQKVPLSFQPGTVLTP---SQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
PAA P +++ P S VLTP S P +P P +P S A S
Sbjct: 1239 EEPTSPAAAVPTLEE-PTS-SAAAVLTPEELSSPAASVPTPE--EPASPA------AAVS 1288
Query: 475 TLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGS 534
L P P+ + +PE+ + P A SV P EV +P +
Sbjct: 1289 NLEEPASPA--------AAVPTPEVAAIP-AASVPTP----------EVPAIPAAAV--P 1327
Query: 535 TTTQPAPDGVP--GPLADTSLVTASAKVLP 562
+ +P GVP G A T V S + P
Sbjct: 1328 PMEEVSPIGVPFLGVSAHTDSVPISEEGTP 1357
Score = 67.0 bits (162), Expect = 1e-10
Identities = 129/514 (25%), Positives = 187/514 (36%), Gaps = 92/514 (17%)
Query: 202 PICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPA 261
P+ +A+VP +V DA L P P G +VPAP A V AL P
Sbjct: 829 PVLQRPSRTAAVP-TVKDALDAAL----PSPEEGTS----IAAVPAPEGT-AVVAALVPF 878
Query: 262 PPS---VPTLISDSNPLSVSASVLVPVPASAPP-SGPVPLSAPAPAPLSVPVSAPP---- 313
P V +++S +A+V P A+ P + VP A A +S P P
Sbjct: 879 PHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAA 938
Query: 314 ------LALIQAPVPPSAPTLVLAPVP----TPVLAPMPASTPPAAPAPPSVPMPTPTPS 363
++ + P A + P+ TP PA+T A P + + TP
Sbjct: 939 AITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPE 998
Query: 364 SGPPSTPTLIPAFAPTPVPAPTPA-PIFTP-APTPMPAATP---------AAIPT----S 408
P++P A PTP +PA + TP PT AA P AA+PT +
Sbjct: 999 E--PASPA---AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Query: 409 APIPASFSLSRVCFPAAQAPAMQK-------VPLSFQP-------GTVLTPSQPLVYIPP 454
+P A + PAA P ++ VP +P T P+ P +P
Sbjct: 1054 SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1113
Query: 455 PSCGQPLS-VATLPTTLGVSS-----------TLTLPVLPSYLQDRCLPGVLASPELRSY 502
P +P S A +PT +S P +P+ + + +PE +
Sbjct: 1114 PE--EPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESAS 1171
Query: 503 PYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLP 562
P A +V P S S + P TSP+ S P P + L + + AS
Sbjct: 1172 P-AAAVPTPAESASFAAVVATLEEP-TSPAASV---PTPAAMVATLEEFTSPAASVPTSE 1226
Query: 563 TPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPL 622
P L A S P PA E+ T + +P +L AS P E
Sbjct: 1227 EPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVL----TPEELSSPAASVPTPEEPAS 1282
Query: 623 DLSSKSNRQK-------LPLPNQRKTPPMPVLTP 649
++ SN ++ +P P P V TP
Sbjct: 1283 PAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316
Score = 35.8 bits (81), Expect = 0.37
Identities = 63/309 (20%), Positives = 102/309 (33%), Gaps = 20/309 (6%)
Query: 360 PTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSR 419
P+ ++ P+ + A P+P + A + P T + AA + + SL
Sbjct: 834 PSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSLEE 893
Query: 420 --VCFPAAQAPAMQKVP---LSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSS 474
V A AP VP +S GT + P+ ++ + G S
Sbjct: 894 EDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSP 953
Query: 475 -----TLTLPVLPS--YLQDRCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLP 527
+T+P+ + P A V+ P S ++ P
Sbjct: 954 EWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEP 1013
Query: 528 CTSPSGSTTTQPAPDGVPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGT 587
TSP+ + T P + T+ A +PTP+ + P P +
Sbjct: 1014 -TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV 1072
Query: 588 EQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVL 647
E T SP + P E E SP + +P S +P P + +P V
Sbjct: 1073 PTPEEPT----SPAAAVPTPE-EPTSP--AAAVPTPEEPTSPAAAVPTPEEPASPAAAVP 1125
Query: 648 TPVHTSSKA 656
TP +S A
Sbjct: 1126 TPEEPASPA 1134
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,709,114
Number of Sequences: 37866
Number of extensions: 5535898
Number of successful extensions: 105411
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1141
Number of HSP's successfully gapped in prelim test: 2164
Number of HSP's that attempted gapping in prelim test: 29793
Number of HSP's gapped (non-prelim): 29031
length of query: 1711
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1595
effective length of database: 13,855,062
effective search space: 22098823890
effective search space used: 22098823890
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.