Guide to the Human Genome
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Search of human proteins with 33186925

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33186925 AMP-activated protein kinase gamma2 subunit isoform
a [Homo sapiens]
         (569 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33186925 AMP-activated protein kinase gamma2 subunit isoform ...  1128   0.0  
gi|100913192 AMP-activated protein kinase gamma2 subunit isoform...  1043   0.0  
gi|100913189 AMP-activated protein kinase gamma2 subunit isoform...   643   0.0  
gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1 su...   473   e-133
gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3 ...   420   e-117
gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1 s...   370   e-102
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             49   1e-05
gi|188536004 zinc finger protein 469 [Homo sapiens]                    47   4e-05
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        46   8e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    45   1e-04
gi|146198654 zinc finger protein 768 [Homo sapiens]                    45   2e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  44   4e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   44   4e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   44   4e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   44   4e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    44   4e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         44   4e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    43   7e-04
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             43   7e-04
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    43   9e-04
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          43   9e-04
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          43   9e-04
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          43   9e-04
gi|189491742 ataxin 7 isoform b [Homo sapiens]                         42   0.002
gi|4506797 ataxin 7 isoform a [Homo sapiens]                           42   0.002
gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]      42   0.002
gi|210032580 SET domain containing 1B [Homo sapiens]                   41   0.003
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        41   0.003
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora...    40   0.006
gi|239757331 PREDICTED: hypothetical protein [Homo sapiens]            40   0.006

>gi|33186925 AMP-activated protein kinase gamma2 subunit isoform a
           [Homo sapiens]
          Length = 569

 Score = 1128 bits (2917), Expect = 0.0
 Identities = 569/569 (100%), Positives = 569/569 (100%)

Query: 1   MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSS 60
           MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSS
Sbjct: 1   MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSS 60

Query: 61  RKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRR 120
           RKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRR
Sbjct: 61  RKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRR 120

Query: 121 MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESY 180
           MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESY
Sbjct: 121 MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESY 180

Query: 181 KHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEA 240
           KHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEA
Sbjct: 181 KHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPAEA 240

Query: 241 GMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANG 300
           GMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANG
Sbjct: 241 GMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANG 300

Query: 301 VRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKP 360
           VRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKP
Sbjct: 301 VRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKP 360

Query: 361 LVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAF 420
           LVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAF
Sbjct: 361 LVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAF 420

Query: 421 MKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVIN 480
           MKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVIN
Sbjct: 421 MKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVIN 480

Query: 481 LAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADS 540
           LAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADS
Sbjct: 481 LAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADS 540

Query: 541 IVGIISLSDILQALILTPAGAKQKETETE 569
           IVGIISLSDILQALILTPAGAKQKETETE
Sbjct: 541 IVGIISLSDILQALILTPAGAKQKETETE 569


>gi|100913192 AMP-activated protein kinase gamma2 subunit isoform c
           [Homo sapiens]
          Length = 525

 Score = 1043 bits (2697), Expect = 0.0
 Identities = 525/525 (100%), Positives = 525/525 (100%)

Query: 45  MPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKT 104
           MPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKT
Sbjct: 1   MPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKT 60

Query: 105 VFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPS 164
           VFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPS
Sbjct: 61  VFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPS 120

Query: 165 TPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYA 224
           TPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYA
Sbjct: 121 TPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYA 180

Query: 225 PSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFD 284
           PSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFD
Sbjct: 181 PSKAAALAAALGPAEAGMLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFD 240

Query: 285 TTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEH 344
           TTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEH
Sbjct: 241 TTLQVKKAFFALVANGVRAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEH 300

Query: 345 KIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRI 404
           KIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRI
Sbjct: 301 KIETWRELYLQETFKPLVNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRI 360

Query: 405 LKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVD 464
           LKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVD
Sbjct: 361 LKFLQLFMSDMPKPAFMKQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVD 420

Query: 465 ESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRI 524
           ESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRI
Sbjct: 421 ESGKVVDIYSKFDVINLAAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRI 480

Query: 525 VRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE 569
           VRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE
Sbjct: 481 VRAEVHRLVVVNEADSIVGIISLSDILQALILTPAGAKQKETETE 525


>gi|100913189 AMP-activated protein kinase gamma2 subunit isoform b
           [Homo sapiens]
          Length = 328

 Score =  643 bits (1659), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 242 MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 301
           MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV
Sbjct: 1   MLEKLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGV 60

Query: 302 RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 361
           RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL
Sbjct: 61  RAAPLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPL 120

Query: 362 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 421
           VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM
Sbjct: 121 VNISPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFM 180

Query: 422 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 481
           KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL
Sbjct: 181 KQNLDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINL 240

Query: 482 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 541
           AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI
Sbjct: 241 AAEKTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSI 300

Query: 542 VGIISLSDILQALILTPAGAKQKETETE 569
           VGIISLSDILQALILTPAGAKQKETETE
Sbjct: 301 VGIISLSDILQALILTPAGAKQKETETE 328


>gi|4506061 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 1 [Homo sapiens]
          Length = 331

 Score =  473 bits (1218), Expect = e-133
 Identities = 233/303 (76%), Positives = 270/303 (89%)

Query: 255 DSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAAPLWESKKQSF 314
           +S + VY  FM+SH+CYD++PTSSKLVVFDT+LQVKKAFFALV NGVRAAPLW+SKKQSF
Sbjct: 23  ESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALVTNGVRAAPLWDSKKQSF 82

Query: 315 VGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAV 374
           VGMLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV
Sbjct: 83  VGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAV 142

Query: 375 YSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYH 434
            SLI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY 
Sbjct: 143 SSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYA 202

Query: 435 NIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITV 494
           NIA +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++V
Sbjct: 203 NIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSV 262

Query: 495 TQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQAL 554
           T+ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL
Sbjct: 263 TKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQAL 322

Query: 555 ILT 557
           +LT
Sbjct: 323 VLT 325


>gi|47132577 AMP-activated protein kinase, non-catalytic gamma-3
           subunit [Homo sapiens]
          Length = 489

 Score =  420 bits (1079), Expect = e-117
 Identities = 200/316 (63%), Positives = 267/316 (84%), Gaps = 1/316 (0%)

Query: 245 KLEFEDEAVEDSESGVYMRFMRSHKCYDIVPTSSKLVVFDTTLQVKKAFFALVANGVRAA 304
           KL ++DE +    + +YMRFM+ H CYD + TSSKLV+FDT L++KKAFFALVANGVRAA
Sbjct: 169 KLGWDDE-LRKPGAQIYMRFMQEHTCYDAMATSSKLVIFDTMLEIKKAFFALVANGVRAA 227

Query: 305 PLWESKKQSFVGMLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNI 364
           PLW+SKKQSFVGMLTITDFI +LHRYY+SP+VQIYE+E+HKIETWRE+YLQ  FKPLV+I
Sbjct: 228 PLWDSKKQSFVGMLTITDFILVLHRYYRSPLVQIYEIEQHKIETWREIYLQGCFKPLVSI 287

Query: 365 SPDASLFDAVYSLIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQN 424
           SP+ SLF+AVY+LIKN+IHRLPV+DP+SGN L+ILTHKR+LKFL +F S +P+P+F+ + 
Sbjct: 288 SPNDSLFEAVYTLIKNRIHRLPVLDPVSGNVLHILTHKRLLKFLHIFGSLLPRPSFLYRT 347

Query: 425 LDELGIGTYHNIAFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAE 484
           + +LGIGT+ ++A +    PI+ AL+IFV+RR+SALPVV+E G+VV +YS+FDVI+LAA+
Sbjct: 348 IQDLGIGTFRDLAVVLETAPILTALDIFVDRRVSALPVVNECGQVVGLYSRFDVIHLAAQ 407

Query: 485 KTYNNLDITVTQALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGI 544
           +TYN+LD++V +AL+ R+   EGV+ C   E L  ++DRI R +VHRLV+V+E   ++G+
Sbjct: 408 QTYNHLDMSVGEALRQRTLCLEGVLSCQPHESLGEVIDRIAREQVHRLVLVDETQHLLGV 467

Query: 545 ISLSDILQALILTPAG 560
           +SLSDILQAL+L+PAG
Sbjct: 468 VSLSDILQALVLSPAG 483


>gi|47132575 AMP-activated protein kinase, noncatalytic gamma-1
           subunit isoform 2 [Homo sapiens]
          Length = 247

 Score =  370 bits (950), Expect = e-102
 Identities = 184/241 (76%), Positives = 213/241 (88%)

Query: 317 MLTITDFINILHRYYKSPMVQIYELEEHKIETWRELYLQETFKPLVNISPDASLFDAVYS 376
           MLTITDFINILHRYYKS +VQIYELEEHKIETWRE+YLQ++FKPLV ISP+ASLFDAV S
Sbjct: 1   MLTITDFINILHRYYKSALVQIYELEEHKIETWREVYLQDSFKPLVCISPNASLFDAVSS 60

Query: 377 LIKNKIHRLPVIDPISGNALYILTHKRILKFLQLFMSDMPKPAFMKQNLDELGIGTYHNI 436
           LI+NKIHRLPVIDP SGN LYILTHKRILKFL+LF+++ PKP FM ++L+EL IGTY NI
Sbjct: 61  LIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKPEFMSKSLEELQIGTYANI 120

Query: 437 AFIHPDTPIIKALNIFVERRISALPVVDESGKVVDIYSKFDVINLAAEKTYNNLDITVTQ 496
           A +   TP+  AL IFV+ R+SALPVVDE G+VVDIYSKFDVINLAAEKTYNNLD++VT+
Sbjct: 121 AMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAAEKTYNNLDVSVTK 180

Query: 497 ALQHRSQYFEGVVKCNKLEILETIVDRIVRAEVHRLVVVNEADSIVGIISLSDILQALIL 556
           ALQHRS YFEGV+KC   E LETI++R+V AEVHRLVVV+E D + GI+SLSDILQAL+L
Sbjct: 181 ALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLSDILQALVL 240

Query: 557 T 557
           T
Sbjct: 241 T 241


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 58/196 (29%), Positives = 79/196 (40%), Gaps = 28/196 (14%)

Query: 67   FGPGSP-----SKGFFSRGPQPRPSSPMSAPVRPKTSPGSPK------TVFPFSYQESP- 114
            + P SP     S  +    P   P+SP  +P  P  SP SP+      T  P S   SP 
Sbjct: 1769 YSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPS 1828

Query: 115  -----PRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSS--SPSTPT 167
                 P SP+    S  +  SS E +P S P  SP   ++   S K S  S   SP+TP 
Sbjct: 1829 SPSYSPTSPKYTPTSPSYSPSSPEYTPTS-PKYSPTSPKYSPTSPKYSPTSPTYSPTTPK 1887

Query: 168  QVTKQHTFPLESYKHEPERLENRIYASSSP--PDTGQRFCPSS-FQSPTRP--PLASPTH 222
                  T+   S  + P   +   Y+ +SP    T  ++ P+S   SPT P     SPT 
Sbjct: 1888 YSPTSPTYSPTSPVYTPTSPK---YSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTS 1944

Query: 223  YAPSKAAALAAALGPA 238
               S  +   +   PA
Sbjct: 1945 PGYSPTSPTYSLTSPA 1960



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 54/161 (33%), Positives = 71/161 (44%), Gaps = 25/161 (15%)

Query: 67   FGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQ-ESPPRSPRRMSFSG 125
            + P SPS  +    P   P+SP  +P  P  SP SP      SY   SP  SP   S+S 
Sbjct: 1692 YSPTSPS--YSPTSPSYSPTSPSYSPTSPSYSPTSP------SYSPTSPSYSPTSPSYSP 1743

Query: 126  IFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPE 185
               + S  +SPN  P TSP     +S +  +   +S   TPT      T P  S      
Sbjct: 1744 TSPNYS-PTSPNYTP-TSPS----YSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSY 1797

Query: 186  RLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPS 226
               +  Y+ SSP     R+ P   QSPT  P +SP+ Y+PS
Sbjct: 1798 SPTSPSYSPSSP-----RYTP---QSPTYTP-SSPS-YSPS 1828



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/130 (31%), Positives = 57/130 (43%), Gaps = 15/130 (11%)

Query: 67   FGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESP------PRSPRR 120
            + P SPS  +    P+  P+SP  +P  PK SP SPK   P S   SP      P SP  
Sbjct: 1839 YTPTSPS--YSPSSPEYTPTSPKYSPTSPKYSPTSPK-YSPTSPTYSPTTPKYSPTSPTY 1895

Query: 121  MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTS-----GLSSSPSTPTQVTKQHTF 175
               S ++  +S + SP S P  SP   ++   S   S     G + SP++P       T+
Sbjct: 1896 SPTSPVYTPTSPKYSPTS-PTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTY 1954

Query: 176  PLESYKHEPE 185
             L S    P+
Sbjct: 1955 SLTSPAISPD 1964



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 47/166 (28%), Positives = 66/166 (39%), Gaps = 17/166 (10%)

Query: 65   SPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFS 124
            SP  PG  S    S G    PS   ++P     SPG      P     SP  SP   S+S
Sbjct: 1571 SPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYS 1630

Query: 125  GIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEP 184
                     +SPN +P TSP      S S   +  S SP++P+      ++   S  + P
Sbjct: 1631 --------PTSPNYSP-TSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1680

Query: 185  ERLENRIYASSSP--PDTGQRFCPSSFQSPTRPPLASPT--HYAPS 226
                +  Y+ +SP    T   + P+S       P  SPT   Y+P+
Sbjct: 1681 ---TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1723


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 53/180 (29%), Positives = 71/180 (39%), Gaps = 27/180 (15%)

Query: 87  SPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGG 146
           SP        T PG+    F  +  +  P     +    +  +S  ES P  +PAT+  G
Sbjct: 544 SPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSES-PLPSPATNTAG 602

Query: 147 IRFFSRSRKTSGLSSSPSTPTQVTKQHTFPL--ESYKHEPERLENRIYASSSPPDTGQRF 204
               S     S +SSSP+ P+    Q   PL   ++ H P          + P +TG   
Sbjct: 603 ----STCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPP----------THPQETG--- 645

Query: 205 CPSSFQSPTRPPLASPTHYAPSKAAAL---AAALGPAEA-GMLEKLEFEDEAVEDSESGV 260
             S F SP  PP + PTHY P  A A    A  LG   A   LE+  F  E  E    G+
Sbjct: 646 --SPFPSP-EPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGL 702



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 46/180 (25%), Positives = 60/180 (33%), Gaps = 20/180 (11%)

Query: 68   GPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
            G GS   G  S G +PR +  +    RP   P  P+T  P S  +  PR PR  +     
Sbjct: 966  GSGSGGGGRAS-GLRPRRNDGLGE--RPPPRPRRPRTQAPGSRADPAPRVPRAAALPEET 1022

Query: 128  RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERL 187
            RSS +   P   P   P       R RK  G +       ++ +Q    L  Y    E  
Sbjct: 1023 RSSRRRRLP---PRKDP-------RKRKARGGAWGKELILKIVQQKN-RLREYDFASESE 1071

Query: 188  ENRIYASSSPPDTGQRFCPSS------FQSPTRPPLASPTHYAPSKAAALAAALGPAEAG 241
            E+       P   G+R            Q P       P   A  +A    A   P E G
Sbjct: 1072 EDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG 1131


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 58/225 (25%), Positives = 87/225 (38%), Gaps = 26/225 (11%)

Query: 23  KKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSP---FGPGSPSKGFFSR 79
           KK+  +K +S+ V + D +  A           G  + RKV        P +P     + 
Sbjct: 505 KKDGLRKIQSMGVRVMDTNWVAR---------RGSSAGRKVSCAPPSMQPPAPPAELAAP 555

Query: 80  GPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSN 139
            P P P  P+ +P  P  SP           Q  P R+    S   +   S+++ SP S+
Sbjct: 556 LPSPLPEQPLDSPAAPALSPSG------LGLQPGPERTSTTKS-KELSPGSAQKGSPGSS 608

Query: 140 PATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHE--PERLENRIYASSSP 197
             T+  G +  ++     G S SPS P      HT    S K    P ++      + + 
Sbjct: 609 QGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPFGQPGAMAD 668

Query: 198 PDTGQRFCPSSFQ-SPTRPPLASPTHYAPSKAAALAAA-LGPAEA 240
              GQ   PS    SPT P   SP   +  +  +LA+  L PA A
Sbjct: 669 QSAGQ---PSPVSLSPTPPSTPSPYGLSYPQGYSLASGQLSPAAA 710


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/179 (25%), Positives = 63/179 (35%), Gaps = 18/179 (10%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
            P SP  G  +  P+  P++P + P  PK  P +P    P     +PP +       G+  
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP----PPKGAPTPPAATPPSLKGGLAT 1280

Query: 129  SSSKES---------SPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLES 179
               K +         SP   PATSP        +        SP TP         P   
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP----PPKGAPTPP 1336

Query: 180  YKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALGPA 238
                P         +++P   G    PSS + PT PP A+P+H         +   GPA
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPT-PPAATPSHKGGPAMTPPSPKRGPA 1394



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 50/187 (26%), Positives = 71/187 (37%), Gaps = 23/187 (12%)

Query: 65   SPFG-PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSP---GSPKTVFPFSYQESPPRSPRR 120
            SP G PG+P        P   P SP   P  P T+P   G P T         P  +P  
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 121  MSFSGIFRSSSKES----SPNSNPATSPGGIRFFSRSRKTSGLS-SSPSTPTQ--VTKQH 173
                 +   S K      SP  +P TSP  I    +    + ++    +TP++  +T   
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDP-TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437

Query: 174  TFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAA 233
              P+ S K  P        A+S+P   G    PSS   PT P +  P+   P     +A 
Sbjct: 1438 VTPV-SLKKAP--------ATSAPK--GGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486

Query: 234  ALGPAEA 240
            +  P +A
Sbjct: 1487 SSSPKKA 1493



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 46/179 (25%), Positives = 68/179 (37%), Gaps = 24/179 (13%)

Query: 65   SPFGPGSPSKGFFSRGPQPRPSSP--MSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMS 122
            SP  P +P +   S  P+  P++P  M AP  P   P SPK V         P +P    
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP---- 1529

Query: 123  FSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGL---SSSPSTPT--QVTKQHTFPL 177
             +    S    ++     A  P  +   S  +KT  +     +P+TP+  + +       
Sbjct: 1530 -TATLLSKKTPATLAPKEALIPPAMTVPS-PKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587

Query: 178  ESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALAAALG 236
             +YK  P   E  I     PP       PS  ++PT P +  P   +P K  A  A  G
Sbjct: 1588 STYKGAPSPKELLI-----PPAVTS---PSPKEAPTPPAVTPP---SPEKGPATPAPKG 1635



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 30/112 (26%), Positives = 47/112 (41%), Gaps = 5/112 (4%)

Query: 133 ESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHT----FPLESYKHEPERLE 188
           E S  S  A+S G + + + S    G+S SP T    TK+ +     P+ +       +E
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832

Query: 189 NRIYASSSPPDTGQRFCPSSFQSPTRP-PLASPTHYAPSKAAALAAALGPAE 239
                 +S    G +  P++  SPT P P  +PT  A +  +     L P E
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKE 884



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 43/168 (25%), Positives = 66/168 (39%), Gaps = 25/168 (14%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
            P SP  G  +  P+  P++P + P  PK    +P      +   + P SP+     G+  
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK----GGLAT 1188

Query: 129  SSSK--ESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTP--TQVTKQHTFPLESYKHEP 184
             S K   ++P + P +  GG+        T     +P+TP  T  + +      S K  P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGL-------ATPSPKGAPTTPAATPPSPKGGLATPSPKGAP 1241

Query: 185  ERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALA 232
                    A++ P   G    P    +PT PP A+P    PS    LA
Sbjct: 1242 -----TTPAATPPSPKGGPATPPPKGAPT-PPAATP----PSLKGGLA 1279



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 51/195 (26%), Positives = 68/195 (34%), Gaps = 20/195 (10%)

Query: 52   LEGSGKHSSRKVDSPFG-PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVF---- 106
            +  S    +R   +P G P SPS       P+  P+ P + P  PK  P +P   +    
Sbjct: 913  MTSSSPKKARATPAPKGIPASPS-------PKGAPTPPAATPPSPKGGPATPSPKWAPTP 965

Query: 107  PFSYQESPPRSPRRMSFSGI-FRSSSKESSPNSNPAT-SPGGIRFFSRSRKTSGLSSSPS 164
            P +   SP   P   S  G     ++   SP   PAT SP G          S   S  +
Sbjct: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025

Query: 165  TPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPL-ASPTHY 223
            TP    K  + P  +    P+            P T     PS    P  P L  +PT  
Sbjct: 1026 TP--FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT-- 1081

Query: 224  APSKAAALAAALGPA 238
             P  A   +   GPA
Sbjct: 1082 -PPAATPPSPKGGPA 1095



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 31/163 (19%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
            P SP  G  +  P+  P++P + P  PK    +P      +   + P SP+     G+  
Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK----GGLAT 1211

Query: 129  SSSK--ESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
             S K   ++P + P +  GG+        T     +P+TP            S K  P  
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGL-------ATPSPKGAPTTPAATP-------PSPKGGP-- 1255

Query: 187  LENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHY-APSKA 228
                    ++PP  G    P++     +  LA+P H  AP+ A
Sbjct: 1256 --------ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 43/181 (23%), Positives = 63/181 (34%), Gaps = 16/181 (8%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
            P SP  G  +  P+  P+ P + P  PK  P +P      +   + P SP+     G   
Sbjct: 947  PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK-----GGPA 1001

Query: 129  SSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLE 188
            + S + +P     T P      + +    G S+ P+      K         K  P    
Sbjct: 1002 TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP---- 1057

Query: 189  NRIYASSSPPDTGQRFCPSSFQSPTRP------PLASPTHYAPSKAAALAAALGPAEAGM 242
                A++ P   G    PS   +PT P      P   P   +P  A    AA  P+  G 
Sbjct: 1058 -TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116

Query: 243  L 243
            L
Sbjct: 1117 L 1117



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 38/156 (24%), Positives = 58/156 (37%), Gaps = 26/156 (16%)

Query: 60   SRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPR 119
            S K      P SP +G     P+  P+SP   P+ PK +P +P T               
Sbjct: 1377 SHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT--------------- 1421

Query: 120  RMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLES 179
                 G    S  + +P   PA +P  ++   ++  TS     P+TP+      T P  +
Sbjct: 1422 ---REGAATPSKGDLTP---PAVTPVSLK---KAPATSAPKGGPATPSS-KGDPTLPAVT 1471

Query: 180  YKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRP 215
                 E    +  A+SS P       P+   +PT P
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPA-TPAPMGAPTLP 1506



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 47/186 (25%), Positives = 66/186 (35%), Gaps = 32/186 (17%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRM--SFSGI 126
            P SP  G       P   SP  AP+ P  +P SPK        +  P +P     S  G 
Sbjct: 1087 PPSPKGG-------PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 127  FRSSSKESSPNSNPATSP---GGIRFFSRSRKTSGLSSSPSTP--TQVTKQHTFPLESYK 181
              +   + +P +  AT P   GG+        T     +P+TP  T  + +      S K
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGL-------ATPPPKGAPTTPAATPPSPKGGLATPSPK 1192

Query: 182  HEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHY------APSKAAALAAAL 235
              P        A++ P   G    PS   +PT P    P+        +P  A    AA 
Sbjct: 1193 GAP-----TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1247

Query: 236  GPAEAG 241
             P+  G
Sbjct: 1248 PPSPKG 1253



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 46/184 (25%), Positives = 62/184 (33%), Gaps = 29/184 (15%)

Query: 68   GPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
            GP +PS       P   P SP   P  P     SPK   P     +PP SP+     G  
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATP-----SPKGA-PMPPAATPP-SPK-----GGL 1117

Query: 128  RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSP--STPTQVTKQHTFPLESYKHEPE 185
             +   + +P +  AT P             GL++ P    PT        P       P 
Sbjct: 1118 ATPPHKGAPTTPAATPPS---------PKGGLATPPPKGAPTTPAATPPSPKGGLATPPP 1168

Query: 186  RLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHY------APSKAAALAAALGPAE 239
            +      A++ P   G    PS   +PT P    P+        +P  A    AA  P+ 
Sbjct: 1169 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1228

Query: 240  AGML 243
             G L
Sbjct: 1229 KGGL 1232



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 45/191 (23%), Positives = 69/191 (36%), Gaps = 27/191 (14%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTV-------FPFSYQESPPR----- 116
            P SP KG  +  P+  P+SP   P   K SP SP +V        P + +  P +     
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA 1680

Query: 117  ------SPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSG----LSSSPSTP 166
                  +P   S   I   + K      + ATSP      S    + G    ++ +P  P
Sbjct: 1681 LKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740

Query: 167  TQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPS 226
             Q     T   +   H P+       + +S P T      ++F+     P ++    APS
Sbjct: 1741 VQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTA-----AAFEKVLPKPESASVSAAPS 1795

Query: 227  KAAALAAALGP 237
               +L  A  P
Sbjct: 1796 PPVSLPLAPSP 1806



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 46/223 (20%), Positives = 79/223 (35%), Gaps = 30/223 (13%)

Query: 44  AMPLLDGDLEGSGKHSSRKVDSPFGPGSPS-KGFFSRGPQPRP---SSPMSAPVRPKTSP 99
           A PL   D  G    +++   +     SP  +G  S  P+  P    +  + P+ P  S 
Sbjct: 647 AFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE 706

Query: 100 GSP------KTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRS 153
             P       T  P +     P  P+ +             SP+  PA +P G +     
Sbjct: 707 NCPVAPSPQNTCAPLATLVLAPEIPKSVP------------SPSLPPAGTPPGTKKVDGI 754

Query: 154 RKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPT 213
             TS L+   S+P +   + +    +   +        Y + SP   G    P + + PT
Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSK----GTLTYLADSPSPLGVSVSPQTKRPPT 810

Query: 214 RPPLASPTHYAPSKAAALAAALGPAEAGMLEKLEFEDEAVEDS 256
           +   A P     +    L++ + P EA  L +     +  +DS
Sbjct: 811 KKGSAGP----DTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 10/143 (6%)

Query: 83  PRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSF--SGIFRSSSKESSPNSNP 140
           P P SP  AP     +P SPK V     +E+P  S   + F   G    + K++   S  
Sbjct: 856 PTPPSPKGAPTPSAVTPLSPKGV-TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 141 ATSPGGIRFFSRSRKTSGLSSSPS---TPTQVTKQHTFPLESYKHEPERLENRIYASSSP 197
           ++SP   R    +    G+ +SPS    PT        P         +      A++ P
Sbjct: 915 SSSPKKAR---ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971

Query: 198 PDTGQRFCPSSFQSPTRPPLASP 220
              G    PS   +PT PP A+P
Sbjct: 972 SPKGGPATPSPKGAPT-PPAATP 993


>gi|146198654 zinc finger protein 768 [Homo sapiens]
          Length = 540

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 62/211 (29%), Positives = 77/211 (36%), Gaps = 27/211 (12%)

Query: 53  EGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQE 112
           EGSG +   ++  PFG    S GF  + P+  P SP   P  P     SP  V P    E
Sbjct: 44  EGSGDYEVEEI--PFGLEPQSPGFEPQSPEFEPQSPRFEPESPGFESRSPGLVPP--SPE 99

Query: 113 SPPRSPRRMSFSGIFRSSS---KESSPNSNPAT------SPGGIRFFSR--SRKTSGLSS 161
             PRSP   S S  F S S   +  SP   P +      SPG     SR  S+ T   + 
Sbjct: 100 FAPRSPESDSQSPEFESQSPRYEPQSPGYEPRSPGYEPRSPGYESESSRYESQNTELKTQ 159

Query: 162 SPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPD----------TGQRFCPSSFQS 211
           SP    Q +K      E   +  E+    I     P D          TG       F+ 
Sbjct: 160 SPEFEAQSSKFQE-GAEMLLNPEEKSPLNISVGVHPLDSFTQGFGEQPTGDLPIGPPFEM 218

Query: 212 PTRPPLASPTHYAPSKAAALAAAL-GPAEAG 241
           PT   L++P          L  AL GP   G
Sbjct: 219 PTGALLSTPQFEMLQNPLGLTGALRGPGRRG 249


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 49/199 (24%), Positives = 70/199 (35%), Gaps = 42/199 (21%)

Query: 52   LEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQ 111
            L+GS   +S+KV  P GPGSP         + + +     PV PK  P            
Sbjct: 1239 LQGSPTPTSKKVPLP-GPGSP---------EVKRAHGTPPPVSPKPPP------------ 1276

Query: 112  ESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTK 171
              PP +P+ +       S S   SP  +PA  P            + L+  P TP  +  
Sbjct: 1277 --PPTAPKPVKAVAGLPSGSAGPSPAPSPARQP-----------PAALAKPPGTPPSLGA 1323

Query: 172  QHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAAL 231
                P       P      ++  + PP        ++   P  P  ASP   A  K    
Sbjct: 1324 SPAKP-------PSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDSARQKLEET 1376

Query: 232  AAALGPAEAGMLEKLEFED 250
            +A L  A   + EK+  ED
Sbjct: 1377 SACLAAALQAVEEKIRQED 1395



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 46/173 (26%), Positives = 64/173 (36%), Gaps = 39/173 (22%)

Query: 81   PQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKES------ 134
            P P P      P +P  SP    T      Q SP  + +++   G      K +      
Sbjct: 1210 PLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPP 1269

Query: 135  -SPN-SNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIY 192
             SP    P T+P  +      +  +GL S  + P+        P  S   +P        
Sbjct: 1270 VSPKPPPPPTAPKPV------KAVAGLPSGSAGPS--------PAPSPARQPPA------ 1309

Query: 193  ASSSPPDTGQRFCPSSFQSPTRPPL-ASPTHYAPSK------AAALAAALGPA 238
            A + PP T     PS   SP +PP   +P  + P+K      AAA AAA  PA
Sbjct: 1310 ALAKPPGTP----PSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPA 1358


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPK-TSPGSPKTVFPFSYQESPPRSPRRMSFSGI 126
           P +P +   +   +P P++P   AP  PK T+P +PK   P + +E  P +P++ +   +
Sbjct: 540 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599

Query: 127 FRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
             +++KE +  +    +P   +  + +       ++P  P   T + T P    +  P  
Sbjct: 600 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 187 LENRIYASSSPPDT-GQRFCPSSFQSPTRPPLASPT 221
            +       +P  T G     S   +PT P   +PT
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/175 (21%), Positives = 69/175 (39%), Gaps = 14/175 (8%)

Query: 59  SSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSP 118
           ++ K  SP  P  P+       P    ++   AP   K++P +PK   P + +E  P +P
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 431

Query: 119 RRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLE 178
           +  +      ++ K+ +P +    +P   +  + +       ++P  P   T + T P  
Sbjct: 432 KEPA-----PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 486

Query: 179 SYKHEPERLENRIYASSSP----PDTGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
             K  P   E    A ++P    P T +   P++ + PT      P    P  AA
Sbjct: 487 PKKLTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 539



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 53/235 (22%), Positives = 94/235 (40%), Gaps = 46/235 (19%)

Query: 8   TKKKKDVSSPGG---SGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKH-SSRKV 63
           T   K  S+ G    +  K+  S ++ S +   P     A P    +    G   ++ K 
Sbjct: 156 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 215

Query: 64  DSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPK--------TSPGSPKTVFPFSYQESPP 115
            +P  P  P+    +   +P P++  SAP  PK        ++P +PK   P + +E  P
Sbjct: 216 PTPTTPKEPAS---TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 272

Query: 116 RSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
            +P+  +      +++KE +P +            ++S  T+    +P+TP +     T 
Sbjct: 273 TTPKEPA-----PTTTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAP--TT 313

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ-SPTRPPLASPTHYAPSKAA 229
           P E     P+            P T +   P++ + +PT P   +PT  AP K A
Sbjct: 314 PKEPAPTTPK---------EPTPTTPKEPAPTTKEPAPTTPKEPAPT--APKKPA 357



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTS-PGSPKTVFPFSYQESPPRSPRR------ 120
           P +P +   +   +P P++P   AP  PK + P +PK   P + +E  P +P+       
Sbjct: 508 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567

Query: 121 -----MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
                 +  G   ++ KE +P +    +P  +   +    TS     P+  T      T 
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ--SPTRPPLASPTHYAPS 226
           P E     P+            P T +   P++ +  +PT P   +P   AP+
Sbjct: 628 PKEPAPTTPK---------EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 671



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 16/160 (10%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
           P +P +   +   +P P++P   AP   + +P +PK   P + ++  P +P+  +     
Sbjct: 311 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----- 365

Query: 128 RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERL 187
            ++ KE +P +    SP       +    +   S+P+T  +     T    +   EP   
Sbjct: 366 PTTPKEPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 421

Query: 188 ENRIYASSSP----PDTGQRFCPSSFQ--SPTRPPLASPT 221
             +  A ++P    P T ++  P++ +  +PT P   +PT
Sbjct: 422 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 461


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPK-TSPGSPKTVFPFSYQESPPRSPRRMSFSGI 126
           P +P +   +   +P P++P   AP  PK T+P +PK   P + +E  P +P++ +   +
Sbjct: 581 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640

Query: 127 FRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
             +++KE +  +    +P   +  + +       ++P  P   T + T P    +  P  
Sbjct: 641 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 187 LENRIYASSSPPDT-GQRFCPSSFQSPTRPPLASPT 221
            +       +P  T G     S   +PT P   +PT
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/175 (21%), Positives = 69/175 (39%), Gaps = 14/175 (8%)

Query: 59  SSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSP 118
           ++ K  SP  P  P+       P    ++   AP   K++P +PK   P + +E  P +P
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 472

Query: 119 RRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLE 178
           +  +      ++ K+ +P +    +P   +  + +       ++P  P   T + T P  
Sbjct: 473 KEPA-----PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 527

Query: 179 SYKHEPERLENRIYASSSP----PDTGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
             K  P   E    A ++P    P T +   P++ + PT      P    P  AA
Sbjct: 528 PKKLTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 580



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 53/235 (22%), Positives = 94/235 (40%), Gaps = 46/235 (19%)

Query: 8   TKKKKDVSSPGG---SGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKH-SSRKV 63
           T   K  S+ G    +  K+  S ++ S +   P     A P    +    G   ++ K 
Sbjct: 197 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 256

Query: 64  DSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPK--------TSPGSPKTVFPFSYQESPP 115
            +P  P  P+    +   +P P++  SAP  PK        ++P +PK   P + +E  P
Sbjct: 257 PTPTTPKEPAS---TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 313

Query: 116 RSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
            +P+  +      +++KE +P +            ++S  T+    +P+TP +     T 
Sbjct: 314 TTPKEPA-----PTTTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAP--TT 354

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ-SPTRPPLASPTHYAPSKAA 229
           P E     P+            P T +   P++ + +PT P   +PT  AP K A
Sbjct: 355 PKEPAPTTPK---------EPTPTTPKEPAPTTKEPAPTTPKEPAPT--APKKPA 398



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTS-PGSPKTVFPFSYQESPPRSPRR------ 120
           P +P +   +   +P P++P   AP  PK + P +PK   P + +E  P +P+       
Sbjct: 549 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608

Query: 121 -----MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
                 +  G   ++ KE +P +    +P  +   +    TS     P+  T      T 
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ--SPTRPPLASPTHYAPS 226
           P E     P+            P T +   P++ +  +PT P   +P   AP+
Sbjct: 669 PKEPAPTTPK---------EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 712



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 16/160 (10%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
           P +P +   +   +P P++P   AP   + +P +PK   P + ++  P +P+  +     
Sbjct: 352 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----- 406

Query: 128 RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERL 187
            ++ KE +P +    SP       +    +   S+P+T  +     T    +   EP   
Sbjct: 407 PTTPKEPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 462

Query: 188 ENRIYASSSP----PDTGQRFCPSSFQ--SPTRPPLASPT 221
             +  A ++P    P T ++  P++ +  +PT P   +PT
Sbjct: 463 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 502


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPK-TSPGSPKTVFPFSYQESPPRSPRRMSFSGI 126
           P +P +   +   +P P++P   AP  PK T+P +PK   P + +E  P +P++ +   +
Sbjct: 633 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692

Query: 127 FRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
             +++KE +  +    +P   +  + +       ++P  P   T + T P    +  P  
Sbjct: 693 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752

Query: 187 LENRIYASSSPPDT-GQRFCPSSFQSPTRPPLASPT 221
            +       +P  T G     S   +PT P   +PT
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/175 (21%), Positives = 69/175 (39%), Gaps = 14/175 (8%)

Query: 59  SSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSP 118
           ++ K  SP  P  P+       P    ++   AP   K++P +PK   P + +E  P +P
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524

Query: 119 RRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLE 178
           +  +      ++ K+ +P +    +P   +  + +       ++P  P   T + T P  
Sbjct: 525 KEPA-----PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 579

Query: 179 SYKHEPERLENRIYASSSP----PDTGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
             K  P   E    A ++P    P T +   P++ + PT      P    P  AA
Sbjct: 580 PKKLTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 53/235 (22%), Positives = 94/235 (40%), Gaps = 46/235 (19%)

Query: 8   TKKKKDVSSPGG---SGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKH-SSRKV 63
           T   K  S+ G    +  K+  S ++ S +   P     A P    +    G   ++ K 
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 308

Query: 64  DSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPK--------TSPGSPKTVFPFSYQESPP 115
            +P  P  P+    +   +P P++  SAP  PK        ++P +PK   P + +E  P
Sbjct: 309 PTPTTPKEPAS---TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 365

Query: 116 RSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
            +P+  +      +++KE +P +            ++S  T+    +P+TP +     T 
Sbjct: 366 TTPKEPA-----PTTTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAP--TT 406

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ-SPTRPPLASPTHYAPSKAA 229
           P E     P+            P T +   P++ + +PT P   +PT  AP K A
Sbjct: 407 PKEPAPTTPK---------EPTPTTPKEPAPTTKEPAPTTPKEPAPT--APKKPA 450



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTS-PGSPKTVFPFSYQESPPRSPRR------ 120
           P +P +   +   +P P++P   AP  PK + P +PK   P + +E  P +P+       
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660

Query: 121 -----MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
                 +  G   ++ KE +P +    +P  +   +    TS     P+  T      T 
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ--SPTRPPLASPTHYAPS 226
           P E     P+            P T +   P++ +  +PT P   +P   AP+
Sbjct: 721 PKEPAPTTPK---------EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 764



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 16/160 (10%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
           P +P +   +   +P P++P   AP   + +P +PK   P + ++  P +P+  +     
Sbjct: 404 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----- 458

Query: 128 RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERL 187
            ++ KE +P +    SP       +    +   S+P+T  +     T    +   EP   
Sbjct: 459 PTTPKEPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 514

Query: 188 ENRIYASSSP----PDTGQRFCPSSFQ--SPTRPPLASPT 221
             +  A ++P    P T ++  P++ +  +PT P   +PT
Sbjct: 515 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 554


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/156 (22%), Positives = 67/156 (42%), Gaps = 3/156 (1%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPK-TSPGSPKTVFPFSYQESPPRSPRRMSFSGI 126
           P +P +   +   +P P++P   AP  PK T+P +PK   P + +E  P +P++ +   +
Sbjct: 674 PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733

Query: 127 FRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
             +++KE +  +    +P   +  + +       ++P  P   T + T P    +  P  
Sbjct: 734 APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793

Query: 187 LENRIYASSSPPDT-GQRFCPSSFQSPTRPPLASPT 221
            +       +P  T G     S   +PT P   +PT
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/175 (21%), Positives = 69/175 (39%), Gaps = 14/175 (8%)

Query: 59  SSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSP 118
           ++ K  SP  P  P+       P    ++   AP   K++P +PK   P + +E  P +P
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPT---TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565

Query: 119 RRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLE 178
           +  +      ++ K+ +P +    +P   +  + +       ++P  P   T + T P  
Sbjct: 566 KEPA-----PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT 620

Query: 179 SYKHEPERLENRIYASSSP----PDTGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
             K  P   E    A ++P    P T +   P++ + PT      P    P  AA
Sbjct: 621 PKKLTPTTPEK--LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 53/235 (22%), Positives = 94/235 (40%), Gaps = 46/235 (19%)

Query: 8   TKKKKDVSSPGG---SGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKH-SSRKV 63
           T   K  S+ G    +  K+  S ++ S +   P     A P    +    G   ++ K 
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKE 349

Query: 64  DSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPK--------TSPGSPKTVFPFSYQESPP 115
            +P  P  P+    +   +P P++  SAP  PK        ++P +PK   P + +E  P
Sbjct: 350 PTPTTPKEPAS---TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAP 406

Query: 116 RSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
            +P+  +      +++KE +P +            ++S  T+    +P+TP +     T 
Sbjct: 407 TTPKEPA-----PTTTKEPAPTT------------TKSAPTTPKEPAPTTPKKPAP--TT 447

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ-SPTRPPLASPTHYAPSKAA 229
           P E     P+            P T +   P++ + +PT P   +PT  AP K A
Sbjct: 448 PKEPAPTTPK---------EPTPTTPKEPAPTTKEPAPTTPKEPAPT--APKKPA 491



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/173 (21%), Positives = 67/173 (38%), Gaps = 24/173 (13%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTS-PGSPKTVFPFSYQESPPRSPRR------ 120
           P +P +   +   +P P++P   AP  PK + P +PK   P + +E  P +P+       
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701

Query: 121 -----MSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTF 175
                 +  G   ++ KE +P +    +P  +   +    TS     P+  T      T 
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761

Query: 176 PLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQ--SPTRPPLASPTHYAPS 226
           P E     P+            P T +   P++ +  +PT P   +P   AP+
Sbjct: 762 PKEPAPTTPK---------EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 805



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 34/160 (21%), Positives = 69/160 (43%), Gaps = 16/160 (10%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMS-APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
           P +P +   +   +P P++P   AP   + +P +PK   P + ++  P +P+  +     
Sbjct: 445 PTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA----- 499

Query: 128 RSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERL 187
            ++ KE +P +    SP       +    +   S+P+T  +     T    +   EP   
Sbjct: 500 PTTPKEPAPTTTKEPSP----TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPT 555

Query: 188 ENRIYASSSP----PDTGQRFCPSSFQ--SPTRPPLASPT 221
             +  A ++P    P T ++  P++ +  +PT P   +PT
Sbjct: 556 TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT 595


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 63/244 (25%), Positives = 87/244 (35%), Gaps = 47/244 (19%)

Query: 9   KKKKDVSSPGGSGGKKNASQKRRS---------LRVHIPDLSSFAMPLLDGDLEGSGKHS 59
           ++ +  SS  GS       + +RS          R H P  S+   P      E S +  
Sbjct: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR-KRQKETSPRGR 545

Query: 60  SRKVDSPF--------GPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQ 111
            R+  SP          P  P +   +  P PR  +P   P R   SP          Y 
Sbjct: 546 RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS 605

Query: 112 ESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRS------------RKTSGL 159
            SPP  P+R       R++S    P    + SP   R  S S            R++  L
Sbjct: 606 PSPP--PKR-------RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656

Query: 160 SS---SPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDT--GQRFCPSSFQSP-- 212
           SS     S+P++ T++   P  + +H P         SSSPP    G    P   QSP  
Sbjct: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSP 716

Query: 213 -TRP 215
            TRP
Sbjct: 717 STRP 720



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 47/166 (28%), Positives = 61/166 (36%), Gaps = 23/166 (13%)

Query: 81  PQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNP 140
           P+ RPS     P  P+  P  P+         SP R  RR S S    SSS  SS + +P
Sbjct: 317 PRRRPSPRRRTP--PRRMPPPPR----HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370

Query: 141 ATSPGGIRFFSRSRKTSGLS------------SSPSTPTQVTKQHTFPLESYKHEPERLE 188
              P   R  S  RKT  LS            S P+TP   T+    P +S +    R+ 
Sbjct: 371 PKKPPK-RTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429

Query: 189 NRIYASSSP----PDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAA 230
                +S        T +R  PS    P +  L+        K AA
Sbjct: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAA 475



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 42/163 (25%), Positives = 60/163 (36%), Gaps = 15/163 (9%)

Query: 69  PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
           P  P K   S  P P+     S P + ++SP + +     S +     SP R +      
Sbjct: 617 PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP 676

Query: 129 SSSKESSPNSNP-----ATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHE 183
             +K  SP+  P     ++SP  +R         G SSSP    Q     T P+      
Sbjct: 677 QPNKRHSPSPRPRAPQTSSSPPPVR--------RGASSSPQR-RQSPSPSTRPIRRVSRT 727

Query: 184 PERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPS 226
           PE  + +  AS SP    +R   S   S +  P A      PS
Sbjct: 728 PEPKKIKKAASPSPQSV-RRVSSSRSVSGSPEPAAKKPPAPPS 769



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 38/156 (24%), Positives = 60/156 (38%), Gaps = 21/156 (13%)

Query: 55  SGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESP 114
           S   SS +  SP  P  P K   S   + R  SP ++P R +  P  P T  P +     
Sbjct: 359 SSSSSSSRSRSP--PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT 416

Query: 115 PRSPRRMSFSGIF----RSSSK-------ESSPNSNPATSPGGIRFFSRSRKTSGLSSSP 163
           P+   R   S +     R+S K       E   + +PA  P  +   S S +  G   + 
Sbjct: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE-LSESEEDKGGKMAA 475

Query: 164 STPTQVTKQHTFPLESYKHEPERLENRIYASSSPPD 199
           +   Q  +Q       Y+ + ++  +   +SSS  D
Sbjct: 476 ADSVQQRRQ-------YRRQNQQSSSDSGSSSSSED 504


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 50/182 (27%), Positives = 68/182 (37%), Gaps = 18/182 (9%)

Query: 58  HSSRKVD-SPFGPGSPSKGFFSRGPQPRPSSPMS-APVRP-KTSPGSPKTVFPFSYQESP 114
           H SR ++ SP  P  P +   S  P+  P SP+  +P+ P + SP SP    P S    P
Sbjct: 484 HLSRPLEESPLSP-PPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS----P 538

Query: 115 PRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLS----SSPSTPTQVT 170
           P  P     S  F  S     P   P + P      S   + S +S     SP +P    
Sbjct: 539 P--PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596

Query: 171 KQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAA 230
            +   P E     P   E+ +    SPP    R  P    SP  PP        P + + 
Sbjct: 597 SRLFPPFEESPLSPPPEESPL----SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSR 652

Query: 231 LA 232
           L+
Sbjct: 653 LS 654



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 45/144 (31%), Positives = 57/144 (39%), Gaps = 17/144 (11%)

Query: 78  SRGPQPRPSSPMSAPVRPKTSPGSP----KTVFPFSYQESPPRSPRRMS-FSGIFRSSSK 132
           SR   P   SPMS P  P+ SP SP      +FP  ++ESP   P   S  S    +S  
Sbjct: 570 SRLSPPPEESPMSPP--PEESPMSPPPEASRLFP-PFEESPLSPPPEESPLSPPPEASRL 626

Query: 133 ESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIY 192
              P  +P + P      S   + S LS     P  V  + + P E     P   E+   
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLS-----PLPVVSRLSPPPEESPLSPPPEES--- 678

Query: 193 ASSSPPDTGQRFCPSSFQSPTRPP 216
             +SPP    R  P    SPT PP
Sbjct: 679 -PTSPPPEASRLSPPPEDSPTSPP 701



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 48/172 (27%), Positives = 62/172 (36%), Gaps = 31/172 (18%)

Query: 64  DSPFGPGSPSKGFFSRGPQPRPSSPMSAPV---RP-KTSPGSPKTVFPFSYQESPPRSPR 119
           +SP  P  P     S  P+  P+SP+   +   RP + SP SP    P     SPP  P 
Sbjct: 455 ESPTSP-PPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPP---PEESPLSPP--PE 508

Query: 120 RMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLES 179
              FS +      E SP S P  SP            S    +P +P       + P E 
Sbjct: 509 SSPFSPL------EESPLSPPEESP-----------PSPALETPLSPPPEASPLSPPFEE 551

Query: 180 YKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAAL 231
               P   E      +SPP    R  P   +SP  PP        P +A+ L
Sbjct: 552 SPLSPPPEE----LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 48/197 (24%), Positives = 70/197 (35%), Gaps = 41/197 (20%)

Query: 71   SPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTV-FPFSYQESPPR---SPRRMSFSGI 126
            SPS G    G + +      AP+ P+ S   P++       QE PP    +P   S   I
Sbjct: 2309 SPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI 2368

Query: 127  FRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPER 186
            FR  S  + P + P  +P                  P          + P + +   P  
Sbjct: 2369 FRPGS-YTDPYAQPPLTPRP-------------QPPPPESCCALPPRSLPSDPFSRVPAS 2414

Query: 187  LENRIYASSSP----PDTGQRFCPS----SFQSP---TRP-----------PLASPTHYA 224
             +++  +S SP    P + + FCPS     FQSP   +RP           PL  P    
Sbjct: 2415 PQSQ-SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQ 2473

Query: 225  PSKAAALAAALGPAEAG 241
            P + A  A +L     G
Sbjct: 2474 PPEVAFKAGSLAHTSLG 2490


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 68/260 (26%), Positives = 94/260 (36%), Gaps = 30/260 (11%)

Query: 1   MGSAVMDTKKKKDVSSPGGSGGKKNASQKRRSLRVHIPDLSS-FAMPLLDGDLEGSGKHS 59
           + S   D++    +S      G+K  SQ+    R   P   S +  P  +G   GSG+ S
Sbjct: 265 LSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNG---GSGQRS 321

Query: 60  SRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPR 119
                 P    SP     S  P+ R  +  +AP  P     SP    P S   S  R  R
Sbjct: 322 GAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPS---PRSAPSSQGRGGR 378

Query: 120 RMSFSG--------IFRSSSKESSP------NSNPATSPGGIRFFSRSRKTSGLSS---- 161
               +G          RS S  S+P         PA   G  R  SR+R +S   S    
Sbjct: 379 AAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGA 438

Query: 162 -SPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCP---SSFQSPTRPPL 217
             P       + H    +  K  P R       S SP   G+R  P   SS +SP   P 
Sbjct: 439 PGPGPEPGSERGHGGHGKRAKERPPR-ARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPR 497

Query: 218 ASPTHYAPSKAAALAAALGP 237
           +  +  +PSK+ + +A   P
Sbjct: 498 SWSSSRSPSKSRSRSAEKRP 517



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 59/229 (25%), Positives = 85/229 (37%), Gaps = 31/229 (13%)

Query: 18  GGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLE-------GSGKHSSR---KVDSPF 67
           GG+G ++   ++RR  R      SS + P   G          GS +  SR     DS  
Sbjct: 381 GGAGRRRRRRRRRRRSR------SSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGS 434

Query: 68  GPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIF 127
           G G+P       GP P P S        K +   P    P S   SP    RR    G  
Sbjct: 435 GRGAP-------GPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEG-- 485

Query: 128 RSSSKESSPNS---NPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEP 184
           +SSS+   P+    + + SP   R  S  ++    S SPS    +++       +   E 
Sbjct: 486 KSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEA 545

Query: 185 ERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASP---THYAPSKAAA 230
           E    R  + S  P   +R    SF  P R   A      +Y PS +++
Sbjct: 546 EATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSS 594


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 62/257 (24%), Positives = 98/257 (38%), Gaps = 34/257 (13%)

Query: 3   SAVMDTKKKKDVSSPGGSGGKKNASQ--KRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSS 60
           +++  T  +   +SP G+  + + S      SL   +P  S   M           + S 
Sbjct: 272 ASITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGM---------LSRTSL 322

Query: 61  RKVDSPFGPG-SPSKGFFSRGP-------QPRPSSPMSAPVRPKTSPGSPKT--VFPFSY 110
            K+DS      +P +   +R P       +P  +SP   P R   + GSP T  +   S 
Sbjct: 323 TKMDSTASISRTPPRASITRTPSRASPTGKPSTASPTGTPSRASPT-GSPSTASLTGLSS 381

Query: 111 QESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVT 170
             SP  +P R S +G   ++S    P   P  SP G+   +   K    +S   TP + +
Sbjct: 382 TASPTGTPPRASPTGTPSTASLTRKP---PRASPTGMLSRTSITKMDSTASPTRTPPRAS 438

Query: 171 KQHTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAA 230
              T P  S    P R        +SP  T     P+   S T  P  SP+  +P+ + +
Sbjct: 439 PTGTPPRASPTGTPSR--------ASPTGTQSTASPTGSPS-TASPTGSPSTASPTGSPS 489

Query: 231 LAAALGPAEAGMLEKLE 247
            A+         L K+E
Sbjct: 490 RASLTRTPSRASLTKME 506



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 43/160 (26%), Positives = 63/160 (39%), Gaps = 28/160 (17%)

Query: 70  GSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRS 129
           GSPS+   +R P  R S   +      T+P           + S  R+P  +  + +  S
Sbjct: 540 GSPSRAALTRTPS-RASLTRTPSRASLTTPS----------RASLTRTPSTVLLTRMPPS 588

Query: 130 SSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLEN 189
           +S    P+    TSP G+   +   K    +S   TP + +   T P  S    P R   
Sbjct: 589 ASPTGMPSR---TSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPPR--- 642

Query: 190 RIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
                +SP  T  R  P+       PP ASPT   PS+A+
Sbjct: 643 -----ASPTGTPPRASPTG-----TPPRASPTG-TPSRAS 671



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 14/150 (9%)

Query: 83  PRPSSPMSAPVRPKTSP-GSPKTVFPFSYQE--SPPRSPRRMSFSGIFRSSSKESSPNSN 139
           P  +SP   P  P+ SP G+P    P   Q   SP  SP   S +G   ++S   SP+  
Sbjct: 434 PPRASPTGTP--PRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRA 491

Query: 140 PATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPD 199
             T        ++   T+ ++ +PS  +      T         P    +   A  SP  
Sbjct: 492 SLTRTPSRASLTKMESTASITRTPSRASPTWTPST-------ASPTGSPSTALAMGSPSR 544

Query: 200 TGQRFCPSSFQSPTRPPLASPTHYAPSKAA 229
                 PS       P  AS T   PS+A+
Sbjct: 545 AALTRTPSRASLTRTPSRASLT--TPSRAS 572



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 42/152 (27%), Positives = 60/152 (39%), Gaps = 12/152 (7%)

Query: 72  PSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSY--QESPPRSPRRMSFSGIFRS 129
           PS    +R P    +S  + P R   S  +P T    +   + S  R+P R S +    +
Sbjct: 116 PSTASLTRSPSR--ASLTTTPSRASLSM-TPSTAAALTMPSRASLTRTPPRASLTMTPST 172

Query: 130 SSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLEN 189
           +S   +P   P  SP G+   SR+  T   S++  T    T   T  L   +  P     
Sbjct: 173 ASLTRTP---PRASPTGMP--SRTSPTGMPSTASLTKMDSTASITRTLS--RASPTGTPP 225

Query: 190 RIYASSSPPDTGQRFCPSSFQSPTRPPLASPT 221
           R   + SPP       PS+      PP ASPT
Sbjct: 226 RASPTGSPPRASLSMMPSTALLIRTPPRASPT 257



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 43/164 (26%), Positives = 58/164 (35%), Gaps = 14/164 (8%)

Query: 70  GSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPK-----TVFPFSYQESPPRSP--RRMS 122
           G+PS+   S    P  +S M  P R   +   P+     T    S   SP R+   R  S
Sbjct: 24  GTPSRA--SLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMASLMVSPSRASLTRMQS 81

Query: 123 FSGIFRSSSKESSPNSNPATSPGGI---RFFSRSRKTSGLSSSPSTPTQVTKQHTFPLES 179
            S + R+ S  S     P  S           R   T+ L+ SPS  +  T      L  
Sbjct: 82  SSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSPSRASLTTTPSRASLSM 141

Query: 180 YKHEPERLE--NRIYASSSPPDTGQRFCPSSFQSPTRPPLASPT 221
                  L   +R   + +PP       PS+      PP ASPT
Sbjct: 142 TPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTPPRASPT 185


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 44/194 (22%), Positives = 77/194 (39%), Gaps = 25/194 (12%)

Query: 82  QPRPSSPMSAP-VRPKTSPGSPKTVFPFSYQESPPRS-PRRMSFSGIFRSSS-----KES 134
           QP P +P++ P ++P  +   P+   P +++  P  S P   S +               
Sbjct: 362 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 421

Query: 135 SPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLE------ 188
           S +  P+  P  ++   +S+    L SSP+ P  +T+    P     H P  L       
Sbjct: 422 STHHPPSAHPPPLQLMPQSQP---LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 478

Query: 189 ---NRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAP--SKAAALAAALGPAEAGML 243
                 +    PP      CPS+    + PP    T   P  S AAA   ++    +  L
Sbjct: 479 PFAQHPFVPGGPPPITPPTCPST----STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 534

Query: 244 EKLEFEDEAVEDSE 257
             ++ ++EA++D+E
Sbjct: 535 PTVQIKEEALDDAE 548


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 44/194 (22%), Positives = 77/194 (39%), Gaps = 25/194 (12%)

Query: 82   QPRPSSPMSAP-VRPKTSPGSPKTVFPFSYQESPPRS-PRRMSFSGIFRSSS-----KES 134
            QP P +P++ P ++P  +   P+   P +++  P  S P   S +               
Sbjct: 916  QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975

Query: 135  SPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLE------ 188
            S +  P+  P  ++   +S+    L SSP+ P  +T+    P     H P  L       
Sbjct: 976  STHHPPSAHPPPLQLMPQSQP---LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032

Query: 189  ---NRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAP--SKAAALAAALGPAEAGML 243
                  +    PP      CPS+    + PP    T   P  S AAA   ++    +  L
Sbjct: 1033 PFAQHPFVPGGPPPITPPTCPST----STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 1088

Query: 244  EKLEFEDEAVEDSE 257
              ++ ++EA++D+E
Sbjct: 1089 PTVQIKEEALDDAE 1102


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 44/194 (22%), Positives = 77/194 (39%), Gaps = 25/194 (12%)

Query: 82   QPRPSSPMSAP-VRPKTSPGSPKTVFPFSYQESPPRS-PRRMSFSGIFRSSS-----KES 134
            QP P +P++ P ++P  +   P+   P +++  P  S P   S +               
Sbjct: 916  QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSL 975

Query: 135  SPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLE------ 188
            S +  P+  P  ++   +S+    L SSP+ P  +T+    P     H P  L       
Sbjct: 976  STHHPPSAHPPPLQLMPQSQP---LPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP 1032

Query: 189  ---NRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAP--SKAAALAAALGPAEAGML 243
                  +    PP      CPS+    + PP    T   P  S AAA   ++    +  L
Sbjct: 1033 PFAQHPFVPGGPPPITPPTCPST----STPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL 1088

Query: 244  EKLEFEDEAVEDSE 257
              ++ ++EA++D+E
Sbjct: 1089 PTVQIKEEALDDAE 1102


>gi|189491742 ataxin 7 isoform b [Homo sapiens]
          Length = 945

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 12/179 (6%)

Query: 27  SQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPS 86
           S   +S+  H   L+  A P   G ++      SR+V S     S   G  S    P   
Sbjct: 612 SPNSKSVPAHGTTLN--AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSR 669

Query: 87  SPM----SAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPAT 142
            P     S  +RPK S G+       S   S     +R + S +   SS  SS +S+ + 
Sbjct: 670 KPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729

Query: 143 SPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTG 201
           S          RK     S P  P+ VT  H+  L    ++   +  R   S   P TG
Sbjct: 730 S------MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTG 782



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 11/116 (9%)

Query: 81  PQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSP---- 136
           P P  +SP+S  +  +T+   P +    SY  +   S   +  S    S + +S P    
Sbjct: 565 PVPSTTSPISTRIPHRTN-SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623

Query: 137 --NSNPATSPGGIRFFS-RSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLEN 189
             N+ PA S       S +SR+ S  SSSPSTP+ ++   + P+     +P++L++
Sbjct: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM---SRKPQKLKS 676


>gi|4506797 ataxin 7 isoform a [Homo sapiens]
          Length = 892

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/179 (25%), Positives = 65/179 (36%), Gaps = 12/179 (6%)

Query: 27  SQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPS 86
           S   +S+  H   L+  A P   G ++      SR+V S     S   G  S    P   
Sbjct: 612 SPNSKSVPAHGTTLN--AQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPMSR 669

Query: 87  SPM----SAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPAT 142
            P     S  +RPK S G+       S   S     +R + S +   SS  SS +S+ + 
Sbjct: 670 KPQKLKSSKSLRPKESSGNSTNCQNASSSTSGGSGKKRKNSSPLLVHSSSSSSSSSSSSH 729

Query: 143 SPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENRIYASSSPPDTG 201
           S          RK     S P  P+ VT  H+  L    ++   +  R   S   P TG
Sbjct: 730 S------MESFRKNCVAHSGPPYPSTVTSSHSIGLNCVTNKANAVNVRHDQSGRGPPTG 782



 Score = 33.1 bits (74), Expect = 0.70
 Identities = 32/116 (27%), Positives = 55/116 (47%), Gaps = 11/116 (9%)

Query: 81  PQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSP---- 136
           P P  +SP+S  +  +T+   P +    SY  +   S   +  S    S + +S P    
Sbjct: 565 PVPSTTSPISTRIPHRTN-SVPTSQCGVSYLAAATVSTSPVLLSSTCISPNSKSVPAHGT 623

Query: 137 --NSNPATSPGGIRFFS-RSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLEN 189
             N+ PA S       S +SR+ S  SSSPSTP+ ++   + P+     +P++L++
Sbjct: 624 TLNAQPAASGAMDPVCSMQSRQVSSSSSSPSTPSGLSSVPSSPM---SRKPQKLKS 676


>gi|145580582 uromodulin-like 1 isoform 2 precursor [Homo sapiens]
          Length = 1446

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 37/146 (25%), Positives = 59/146 (40%), Gaps = 17/146 (11%)

Query: 71  SPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSS 130
           +PS+G  S+G   + S+  ++P +  TS GSP  V P         S R  S +   + S
Sbjct: 652 NPSQGSPSQGSLRQESTSQASPSQRSTSQGSPSQVNP---------SQRSTSHANSSQGS 702

Query: 131 SKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLENR 190
             + SP+    +     +     R T G+  + S+P      H+FP       P  L  +
Sbjct: 703 PSQGSPSQESPSQGSTSQASPSHRNTIGVIGTTSSPKATGSTHSFP-PGATDGPLALPGQ 761

Query: 191 IYASSSPPDTGQRFCPSSFQSPTRPP 216
           +  +S          P S+ SPT  P
Sbjct: 762 LQGNSIME-------PPSWPSPTEDP 780


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 35/88 (39%), Positives = 43/88 (48%), Gaps = 11/88 (12%)

Query: 81   PQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQES-PPRSPRRMSFSGIFRSSSKESSPNSN 139
            P PRP  P S P  P+T+  S  +V P    E  PP +P      G+  S +K  S  + 
Sbjct: 1283 PPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP------GLCGSLAKSQSTETV 1336

Query: 140  PATSPGGIRFFSRSRKTSGLS-SSPSTP 166
            PAT PGG    S    +SGLS SSP  P
Sbjct: 1337 PAT-PGGEPPLSGG--SSGLSLSSPQVP 1361


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 51/196 (26%), Positives = 77/196 (39%), Gaps = 19/196 (9%)

Query: 54   GSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQES 113
            GS   SS  V +         G  S    P P  P S    P  S G+ +   P +    
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLS---VPAPGVPHSDVGEPPASTGAQQ---PSALAAL 2524

Query: 114  PPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQH 173
             P   RR S S    SSS  SS +S+ ++S  G    S S  + G SS P  P    K+ 
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG----SSSSDSEG-SSLPVQPEVALKRV 2579

Query: 174  TFPLESYKH--------EPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAP 225
              P  + K         EP   + +  +SSS   +      SS  S +    +S +  + 
Sbjct: 2580 PSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639

Query: 226  SKAAALAAALGPAEAG 241
            S +++ +++  PA+ G
Sbjct: 2640 SSSSSSSSSPSPAKPG 2655



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 50/179 (27%), Positives = 71/179 (39%), Gaps = 41/179 (22%)

Query: 46  PLLDGDLEGSGKHSSRKVDSPFG------PGSPSKGFFSR---GPQPRPSSPMS------ 90
           P  D D +   K ++R   SP        P +P+     R    PQP  ++P+S      
Sbjct: 334 PYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP 393

Query: 91  ----APVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGG 146
               +P R ++ P SP+ +   S  ES P SP+    S    +SS   SP   PA +PG 
Sbjct: 394 PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSR--HASSSPESP--KPAPAPGS 449

Query: 147 IRFFSRSRKTSGLSSSPSTPTQVTKQHTFPL--ESYKHEPERLENRIYASSSPPDTGQR 203
            R  S            S+PT   + H      +S+ H P R   R    S  P T +R
Sbjct: 450 HREIS------------SSPTSKNRSHGRAKRDKSHSHTPSRRMGR----SRSPATAKR 492



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 58/197 (29%), Positives = 81/197 (41%), Gaps = 21/197 (10%)

Query: 23   KKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQ 82
            K +AS + RS     PD  +     L    + S   SS +VDS     SP +      P+
Sbjct: 1548 KPSASPQERSESDSSPDSKAKTRTPLR---QRSRSGSSPEVDSK-SRLSPRRSRSGSSPE 1603

Query: 83   PRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPAT 142
             +   P +AP     S  SP+   P       PR+  R S SG   SSSK   P+   ++
Sbjct: 1604 VK-DKPRAAPRAQSGSDSSPEPKAP------APRALPRRSRSG---SSSKGRGPSPEGSS 1653

Query: 143  SPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLE-SYKHEPE-----RLENRIYASSS 196
            S           +T+   S  S+P   TK  T P   S +  PE     RL  R  ++SS
Sbjct: 1654 STESSPEHPPKSRTARRGSR-SSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASS 1712

Query: 197  PPDTGQRFCPSSFQSPT 213
             P+T  R  P   +SP+
Sbjct: 1713 SPETRSRTPPRHRRSPS 1729



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 45/155 (29%), Positives = 60/155 (38%), Gaps = 11/155 (7%)

Query: 55   SGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTS---PGSPKTVFPFSYQ 111
            S   SS    S     S S    S G     S   S PV+P+ +     SP      + +
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVR 2591

Query: 112  ESPPRSP------RRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPST 165
            E  P  P      RR S S    SSS  SS +S+ ++S       S S  +S  SSSPS 
Sbjct: 2592 EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS- 2650

Query: 166  PTQVTKQHTFPLESYKHEPERLENRIYASSSPPDT 200
            P +   Q   P  +   +P   E R  +   P D+
Sbjct: 2651 PAKPGPQ-ALPKPASPKKPPPGERRSRSPRKPIDS 2684



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 41/158 (25%), Positives = 58/158 (36%), Gaps = 16/158 (10%)

Query: 69   PGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFR 128
            P +PS+G       P P +    P     SP SP+         +   +P+R       R
Sbjct: 1470 PRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPEL-------NNKCLTPQRE------R 1516

Query: 129  SSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEPERLE 188
            S S+ S      A +P G R  SRS  +  L   PS   Q   +     +S       L 
Sbjct: 1517 SGSESSVDQKTVARTPLGQR--SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLR 1574

Query: 189  NRIYASSSPP-DTGQRFCPSSFQSPTRPPLASPTHYAP 225
             R  + SSP  D+  R  P   +S + P +      AP
Sbjct: 1575 QRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAP 1612



 Score = 33.5 bits (75), Expect = 0.54
 Identities = 42/136 (30%), Positives = 55/136 (40%), Gaps = 31/136 (22%)

Query: 70   GSPSKGFFSRGPQPRPSSPM-SAPVRPKTSP----GSPKTVFPFSYQESPPRSPRRMSFS 124
            GS SKG   RGP P  SS   S+P  P  S     GS  +  P +   +PPR        
Sbjct: 1639 GSSSKG---RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR-------- 1687

Query: 125  GIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSSSPSTPTQVTKQHTFPLESYKHEP 184
               R SS+         +SP   R    SR++   SSSP T ++   +H         EP
Sbjct: 1688 ---RRSSR---------SSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735

Query: 185  ---ERLENRIYASSSP 197
                R   R  ++SSP
Sbjct: 1736 AEKSRSSRRRRSASSP 1751



 Score = 32.7 bits (73), Expect = 0.92
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 12/141 (8%)

Query: 26   ASQKRRSLRVHIPDLSSFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQ--P 83
            A +KRRS        SS +          S   SS    S     S S      GPQ  P
Sbjct: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660

Query: 84   RPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATS 143
            +P+SP   P      PG  ++  P    +S  R  R +S+S + R   +  SP  +P   
Sbjct: 2661 KPASPKKPP------PGERRSRSPRKPIDS-LRDSRSLSYSPVER---RRPSPQPSPRDQ 2710

Query: 144  PGGIRFFSRSRKTSGLSSSPS 164
                      R   G S SPS
Sbjct: 2711 QSSSSERGSRRGQRGDSRSPS 2731



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 40/147 (27%), Positives = 55/147 (37%), Gaps = 13/147 (8%)

Query: 42  SFAMPLLDGDLEGSGKHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGS 101
           S A P  D     S +   +   S   P SP     SR     P SP  AP     +PGS
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP-----APGS 449

Query: 102 PKTV--FPFSYQESPPRSPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGL 159
            + +   P S   S  R+ R  S S    + S+    + +PAT+  G    SRSR  +  
Sbjct: 450 HREISSSPTSKNRSHGRAKRDKSHS---HTPSRRMGRSRSPATAKRG---RSRSRTPTKR 503

Query: 160 SSSPSTPTQVTKQHTFPLESYKHEPER 186
             S S   Q  +  +         P+R
Sbjct: 504 GHSRSRSPQWRRSRSAQRWGRSRSPQR 530


>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
           homolog, Drosophila); translocated to, 1 [Homo sapiens]
          Length = 559

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 66/274 (24%), Positives = 96/274 (35%), Gaps = 35/274 (12%)

Query: 3   SAVMDTKK------KKDVSSPGGSGGKKNASQKRRSLRVHIPDLSSFAMPLLDGDLEGSG 56
           SA  D KK       KD +       K +   K    R      S  +   L+ +   S 
Sbjct: 167 SAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSS 226

Query: 57  KHSSRKVDSPFGPGSPSKGFFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPR 116
           K +SRK+    G G   K   +  P+     P  A    K    SPK   P      PP 
Sbjct: 227 KDTSRKL----GEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPP----PPPPP 278

Query: 117 SPRRMSFSGIFRSSSKESSPNSNPATSPGGIRFFSRSRKTSGLSS----SPSTPTQVTKQ 172
            PR  S       S K S+     ++S G       S +TS  SS     P+     T+ 
Sbjct: 279 PPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRG 338

Query: 173 HTFPLESYKHEPERLENRIYASSSPPDTGQRFCPSSFQSPTRPPLASPTHYAPSKAAALA 232
                ES   EP   +  +    S  +    F   S QS       SP++ + S  ++  
Sbjct: 339 EKVKAES---EPREAKKALEVEESNSEDEASFKSESAQS-------SPSNSSSSSDSSSD 388

Query: 233 AALGPAE-------AGMLEKLEFEDEAVEDSESG 259
           +   P++         M+E L+ E+   +DS SG
Sbjct: 389 SDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSG 422


>gi|239757331 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 231

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 15/92 (16%)

Query: 76  FFSRGPQPRPSSPMSAPVRPKTSPGSPKTVFPFSYQESPPRSPRRMSFSGIFRSSSKESS 135
           + SR   PRPSSP+S P  P  +   P+++         PRSPR  S     RS S+  S
Sbjct: 2   YMSRLSLPRPSSPLSWPPPPPRASSLPRSL---------PRSPRLCS-----RSRSRSRS 47

Query: 136 PNSNPATSPGGIRFFSRSRKTSGLSSSPSTPT 167
            +   + S   +R  SRSR +   SS PS P+
Sbjct: 48  RSRRRSRSLRWLRRRSRSR-SRPFSSGPSGPS 78


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,752,613
Number of Sequences: 37866
Number of extensions: 1298339
Number of successful extensions: 8550
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 38
Number of HSP's successfully gapped in prelim test: 444
Number of HSP's that attempted gapping in prelim test: 7286
Number of HSP's gapped (non-prelim): 1306
length of query: 569
length of database: 18,247,518
effective HSP length: 108
effective length of query: 461
effective length of database: 14,157,990
effective search space: 6526833390
effective search space used: 6526833390
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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