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Search of human proteins with 12383066
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12383066 axotrophin [Homo sapiens]
(704 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12383066 axotrophin [Homo sapiens] 1385 0.0
gi|154937342 ring finger protein 190 [Homo sapiens] 174 3e-43
gi|154937340 ring finger protein 190 [Homo sapiens] 174 3e-43
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 89 1e-17
gi|60097902 filaggrin [Homo sapiens] 71 4e-12
gi|161016767 mucin 21 [Homo sapiens] 65 2e-10
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 64 4e-10
gi|50083281 KIAA1853 protein [Homo sapiens] 60 9e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 55 2e-07
gi|8923613 membrane-associated RING-CH protein I [Homo sapiens] 54 6e-07
gi|50539414 cellular modulator of immune recognition isoform 7 [... 53 8e-07
gi|50539412 cellular modulator of immune recognition isoform 6 [... 53 8e-07
gi|50539410 cellular modulator of immune recognition isoform 8 [... 53 8e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 2e-06
gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo sapi... 52 2e-06
gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2 ... 50 5e-06
gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1 ... 50 5e-06
gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1 ... 50 5e-06
gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo sapi... 50 9e-06
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 49 2e-05
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens] 48 4e-05
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa... 47 5e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 45 2e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 45 2e-04
gi|50962882 G patch domain containing 8 [Homo sapiens] 45 2e-04
gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo sapi... 44 7e-04
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom... 43 9e-04
gi|167736355 mucin 4 isoform a [Homo sapiens] 43 0.001
gi|239758038 PREDICTED: mucin 3A, cell surface associated, parti... 42 0.001
gi|189011568 adenomatous polyposis coli [Homo sapiens] 42 0.003
>gi|12383066 axotrophin [Homo sapiens]
Length = 704
Score = 1385 bits (3584), Expect = 0.0
Identities = 704/704 (100%), Positives = 704/704 (100%)
Query: 1 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS 60
MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS
Sbjct: 1 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS 60
Query: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR
Sbjct: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
Query: 121 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY 180
HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY
Sbjct: 121 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY 180
Query: 181 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP 240
SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP
Sbjct: 181 SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQP 240
Query: 241 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS 300
GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS
Sbjct: 241 GFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSS 300
Query: 301 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL 360
QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL
Sbjct: 301 QDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSL 360
Query: 361 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR 420
SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR
Sbjct: 361 SHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSR 420
Query: 421 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP 480
SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP
Sbjct: 421 SHIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILP 480
Query: 481 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL 540
GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL
Sbjct: 481 GSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLL 540
Query: 541 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA 600
LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA
Sbjct: 541 LEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEA 600
Query: 601 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN 660
VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN
Sbjct: 601 VTTCELCKEKLELNLEDFDIHELHRAHANEQAEYEFISSGLYLVVLLHLCEQSFSDMMGN 660
Query: 661 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA 704
TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA
Sbjct: 661 TNEPSTRVRFINLARTLQAHMEDLETSEDDSEEDGDHNRTFDIA 704
>gi|154937342 ring finger protein 190 [Homo sapiens]
Length = 808
Score = 174 bits (440), Expect = 3e-43
Identities = 91/187 (48%), Positives = 129/187 (68%), Gaps = 9/187 (4%)
Query: 513 SADGKSDKTKSAPSR-DPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCK 571
+A G +D+ +++ + DPE+L+K++ESLL EDSEEE GDLCRICQ+A S SN L+EPC
Sbjct: 620 AASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEE-GDLCRICQIAGGSPSNPLLEPCG 678
Query: 572 CTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQ 631
C GSLQ+VHQ+C+KKWL+ KI SG+ L AV TCE+CK+ L ++L DF++ E ++ H Q
Sbjct: 679 CVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQ 738
Query: 632 AEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDS 691
A+ E ++SGLYLV+LLHL EQ F+++M + R R L + T E+++
Sbjct: 739 AQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERER-------LSRNYPQPRTEENEN 791
Query: 692 EEDGDHN 698
E GD N
Sbjct: 792 SELGDGN 798
>gi|154937340 ring finger protein 190 [Homo sapiens]
Length = 808
Score = 174 bits (440), Expect = 3e-43
Identities = 91/187 (48%), Positives = 129/187 (68%), Gaps = 9/187 (4%)
Query: 513 SADGKSDKTKSAPSR-DPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCK 571
+A G +D+ +++ + DPE+L+K++ESLL EDSEEE GDLCRICQ+A S SN L+EPC
Sbjct: 620 AASGFTDEKETSKIKADPEKLKKLQESLLEEDSEEE-GDLCRICQIAGGSPSNPLLEPCG 678
Query: 572 CTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEKLELNLEDFDIHELHRAHANEQ 631
C GSLQ+VHQ+C+KKWL+ KI SG+ L AV TCE+CK+ L ++L DF++ E ++ H Q
Sbjct: 679 CVGSLQFVHQECLKKWLKVKITSGADLGAVKTCEMCKQGLLVDLGDFNMIEFYQKHQQSQ 738
Query: 632 AEYEFISSGLYLVVLLHLCEQSFSDMMGNTNEPSTRVRFINLARTLQAHMEDLETSEDDS 691
A+ E ++SGLYLV+LLHL EQ F+++M + R R L + T E+++
Sbjct: 739 AQNELMNSGLYLVLLLHLYEQRFAELMRLNHNQVERER-------LSRNYPQPRTEENEN 791
Query: 692 EEDGDHN 698
E GD N
Sbjct: 792 SELGDGN 798
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 89.0 bits (219), Expect = 1e-17
Identities = 118/530 (22%), Positives = 214/530 (40%), Gaps = 23/530 (4%)
Query: 17 SSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGA 76
SS+ ++ S S +D+ +S DSS DS S S+ +S S S S+ + +
Sbjct: 718 SSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777
Query: 77 RSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFG 136
S + + D + +N + S+ + + + SDS +S +SS S
Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837
Query: 137 TDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQL 196
+ + D +DS SN D S+ S +S S S + NS +
Sbjct: 838 SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897
Query: 197 NTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN 256
+ SS + S + + S DS NS S+ SS S++S S+ S SS ++ S+
Sbjct: 898 SNSSDSDSSDSSNSS--DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955
Query: 257 SERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYV 316
S S+ SSD+ ++ S +S S + S SS S ++ S +S +S
Sbjct: 956 S----SNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 317 SPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQE 376
S +S S ++ S++ + +S++S SS S + S SDS N +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSD-----------SSDSSDSSDSSDSSNSSDS 1060
Query: 377 SEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEA 436
S+ ++ SS + S + D S+ +SD+S S S+ ++
Sbjct: 1061 SDSSDSSD--SSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD----SSDSSDSSDS 1114
Query: 437 QNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNL 496
+ + ++ S+ SS ++ ++SDS+ ++ S S + + S+
Sbjct: 1115 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174
Query: 497 TDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEE 546
+D+ + S + + SD + S+ S D +S DS +
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Score = 87.0 bits (214), Expect = 5e-17
Identities = 131/535 (24%), Positives = 210/535 (39%), Gaps = 33/535 (6%)
Query: 13 SVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEI 72
S S S S+ + S S +D+ S DSS DS+ S+ + + +S S S+S
Sbjct: 587 SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSK--SDSSD 644
Query: 73 TQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVL 132
+ + S + D + ++ + S+ + + + SDSS S SS
Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS-DSSDSSNSSESSD 703
Query: 133 GSFGTDLMRERRDLERRTDSSISNLMDY-SHRSGDFTTSSYVQDRVPSYSQGARPKENSM 191
S +D D +DSS SN D S S D + SS D S S + ++S
Sbjct: 704 SSDSSD-----SDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS-SDSSNSSDSSD 757
Query: 192 STLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEA 251
S+ N+S ++ S S DS NS SN SS S+SS S+ S SS ++
Sbjct: 758 SSDSSNSSDSSDSSDSS-----DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812
Query: 252 PIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNS 311
S+S+ SS SSD+ SS SS S D ++ S N
Sbjct: 813 SDSSDSDSSNSSDS--SNSSDSSD------------SSNSSDSSDSSDSSDGSDSDSSNR 858
Query: 312 ENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSE 371
+S S +S S ++ S+ N +S +S SS S N S SDS
Sbjct: 859 SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 372 NFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEV 431
N + SE N+ +SS + + +SS S SS S +SN
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS----SDSNSS 974
Query: 432 VHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPA 491
++ N + ++ S+ SS ++ +SDS+ ++ S S + +
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034
Query: 492 LGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEE 546
S+ +D+ + S +++ SD + S+ S D +S DS +
Sbjct: 1035 DSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Score = 86.7 bits (213), Expect = 7e-17
Identities = 118/530 (22%), Positives = 214/530 (40%), Gaps = 22/530 (4%)
Query: 21 SARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASA--SPFQSAWYSESEITQGARS 78
S + S S S +D+ +S DSS DS+ +++S+ + S S+ S+S+ + + S
Sbjct: 542 SGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 79 RSQNQQRDHD--SKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFG 136
+ D S S + +S + + ++ SDSS +S +S S
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 137 TDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQL 196
+ + D +DSS S+ S S D + SS + S +S +
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 197 NTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN 256
N+S ++ S+ +S DS +S S+ SS S+SS S+ S SS ++ SN
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 781
Query: 257 SERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYV 316
S S SSD+ SS SS + S DS ++ +S NS
Sbjct: 782 S----SDSNDSSNSSDSSD------------SSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 317 SPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQE 376
S +S S ++ S+ + S++ R SS S + S+ SDS + +
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 377 SEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEA 436
+E N+ SS + S + D S+ +S++S+ S S++ +
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD--NSNSSDSSNSSD 943
Query: 437 QNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNL 496
+D ++ + ++++ SS ++ S S+S+ ++ S S + + SN
Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003
Query: 497 TDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEE 546
+D+ + S + + SD + S+ S D +S DS +
Sbjct: 1004 SDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1053
Score = 84.7 bits (208), Expect = 3e-16
Identities = 124/545 (22%), Positives = 212/545 (38%), Gaps = 23/545 (4%)
Query: 2 ESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASP 61
+S S S S S + S S +D+ +S +SS DS S S+S+S S
Sbjct: 625 DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684
Query: 62 FQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRH 121
S S+ + + S + D DS S + N ++ SDSS +
Sbjct: 685 NSSDSSDSSDSSNSSESSDSSDSSDSDS------------SDSSDSSNSNSSDSDSS--N 730
Query: 122 SQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYS 181
S SS S + D +DSS S+ S S D + SS D S S
Sbjct: 731 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDS-S 789
Query: 182 QGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPG 241
+ ++S S+ N+S ++ S +S DS NS S+ SS S+SS S
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDS----- 844
Query: 242 FSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQ 301
S S D + S++ S+ +SSD+ + SS SS +S
Sbjct: 845 ---SDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 302 DSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLS 361
DS ++ S NS +S S +S+S ++ +++ + +S++S +S
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 362 HNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRS 421
++SS+S N + S+ N+ SS + + +SS S SS S
Sbjct: 962 SSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021
Query: 422 HIFRRESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPG 481
SN ++ + + ++ S+ SS+++ +SDS+ ++ S
Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1081
Query: 482 SLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLL 541
S + + S+ +D+ + S + + SD + S+ S D +S
Sbjct: 1082 SESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 1141
Query: 542 EDSEE 546
DS +
Sbjct: 1142 SDSSD 1146
Score = 73.2 bits (178), Expect = 8e-13
Identities = 103/448 (22%), Positives = 177/448 (39%), Gaps = 20/448 (4%)
Query: 18 SSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGAR 77
SS S+ S + +++ S DSS DS+ +S S+ +S ++ S
Sbjct: 873 SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932
Query: 78 SRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGT 137
S S + DS S + +S + N ++ SDS+ S +SS S +
Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS-SDSNSSDSSDSSNSSDSSDSSDS 991
Query: 138 DLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLN 197
+ D +DSS S+ S S D + SS + S + S +
Sbjct: 992 SDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1051
Query: 198 TSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNS 257
+ S+N S+ S DS +S S+ SS S+SS S+ S SS ++ S+S
Sbjct: 1052 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDS---SDS 1108
Query: 258 ERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVS 317
S S+ ++ ++ S +S+ S + S SS S ++ S +S +S S
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 318 PRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQES 377
+S S ++ S+ + +S++S SS S + S SDS + + S
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSD-----------SSDSSDSSDSSDSSDSSDSS 1217
Query: 378 EGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQ 437
+ ++ SS N S + D S +SD+S S S+ ++Q
Sbjct: 1218 DSSDSSDSSDSSDSNE-----SSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Query: 438 NDPLGAAANRPQASAASSSATTGGSTSD 465
+ N + + S + + STSD
Sbjct: 1273 SKSGNGNNNGSDSDSDSEGSDSNHSTSD 1300
Score = 70.9 bits (172), Expect = 4e-12
Identities = 122/522 (23%), Positives = 201/522 (38%), Gaps = 74/522 (14%)
Query: 26 SGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQR 85
S + S +D Y S D D Q ++S ES A S S N
Sbjct: 439 SNTGSDSNSDGYDSYDFD---DKSMQGDDPNSS---------DESNGNDDANSESDN--- 483
Query: 86 DHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRD 145
+ S R S + + N + D S S S S G+ G D +
Sbjct: 484 -NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 146 LERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQL 205
+ ++DSS S+ S D + SS D S S + +S S+ ++ S++
Sbjct: 543 GKGKSDSSDSD-------SSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS-- 593
Query: 206 PSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQR 265
S DS NS S+ SS S+SS S+ SS+ E+ + + SS
Sbjct: 594 --------DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDS 645
Query: 266 PFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQ 325
+SSDN S +S+ S++ S SS S ++ S +S NS S + S
Sbjct: 646 NSSDSSDNSD--------SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS----SDSS 693
Query: 326 SRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPW 385
SN +S+ D+ S++S S S+++SS+SDS N + S+ N+
Sbjct: 694 DSSNSSESSDSSDSSDSDSSDS----------SDSSNSNSSDSDSSNSSDSSDSSNSSDS 743
Query: 386 L-SSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAA 444
SS N S D S +SD+S S+ +SN+ + +D ++
Sbjct: 744 SDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN--SSDSNDSSNSSDSSDSSNSS 801
Query: 445 ANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGSNLTDNVMITV 504
+ + ++ SS ++ +S+S+ ++ S SN +D+ +
Sbjct: 802 DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD---------------SSNSSDS-SDSS 845
Query: 505 DIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEE 546
D + + +SD + S+ S D +S DS E
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887
Score = 35.8 bits (81), Expect = 0.14
Identities = 31/116 (26%), Positives = 46/116 (39%)
Query: 2 ESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASP 61
+S S S SS S+ S S +D+ S DSS DS S S+ +S S
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSS 1229
Query: 62 FQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDS 117
+ S+ + + S + + D S +N + + GNG N SDS
Sbjct: 1230 DSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDS 1285
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 70.9 bits (172), Expect = 4e-12
Identities = 118/500 (23%), Positives = 179/500 (35%), Gaps = 53/500 (10%)
Query: 21 SARMMSGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARS 78
++R SGSR +S + S DSS S + S A S A +SE ++ +R
Sbjct: 3151 ASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRR 3210
Query: 79 RSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTD 138
+ + +D DS+ + SA RN + S RH PRS G
Sbjct: 3211 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRH---PRSHHEDRAGHGHS 3267
Query: 139 LMRERRDLERRTDSSISNLMDYSHRS-----GDFTTSSYVQDRVPSYSQG---------A 184
R R+ R ++S SH G+ S + Q S G
Sbjct: 3268 ADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAV 3327
Query: 185 RPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSN-FSSRESESSRSNTQPGFS 243
R + S+ + S H S+ Q++ + +S+ S+R+ RS F
Sbjct: 3328 RDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFL 3387
Query: 244 YSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASS--MSSTFFSRRSSQ 301
Y S E ++ S+ R Q S + R ++R S+ SRR Q
Sbjct: 3388 YQVSTHEQSESAHGRTRTSTGRR-QGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
Query: 302 DSLNTRSLNSENSYVSPRILTASQSRSNV---PSASEVPDNRASEASQGFRFLRRRWGLS 358
S +S++ S T SQ RS+ S S + Q R W
Sbjct: 3447 GSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW--- 3503
Query: 359 SLSHNHSSESDSENFNQESEGRNTGPWLS----------------SSLRNRCTPLFSRRR 402
S H S+++DS +Q +G++ GP S S R + SR
Sbjct: 3504 SHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNH 3563
Query: 403 R----EGRDESSRIPTS---DTSSRSHIFRRESNEVVHLEAQNDPLGAAANRPQASAASS 455
R E + SR PTS D + H H A+N G AA+ + + +S+
Sbjct: 3564 RGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTH-HAENSSGGQAASSHEQARSSA 3622
Query: 456 SATTGGSTSDSAQGGRNTGI 475
G SA R++GI
Sbjct: 3623 GERHGSHHQQSADSSRHSGI 3642
Score = 57.8 bits (138), Expect = 3e-08
Identities = 109/459 (23%), Positives = 170/459 (37%), Gaps = 70/459 (15%)
Query: 21 SARMMSGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARS 78
++R SGSR +S + SRD S S + S+ A S A +SE ++ +R
Sbjct: 882 ASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRR 941
Query: 79 RSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTD 138
+ + +D DS+ + SA RN S RH PRS G
Sbjct: 942 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRH---PRSHHEDRAGHGHS 998
Query: 139 LMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNT 198
R+ ++S SG SS+ Q R + P E S Q +
Sbjct: 999 ADSSRQSGTPHAETS----------SGGQAASSHEQAR-------SSPGERHGSRHQQSA 1041
Query: 199 SSTNHQLPSEHQTILSSRDSRN--SLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN 256
S+ H Q + RDS + S S S E S S+TQ S S + P
Sbjct: 1042 DSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQ---SVSGHGQDGP---- 1094
Query: 257 SERVVSSQRPFQESS-DNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSY 315
Q+ QES+ D G R+ R S +F + S+ + SE+++
Sbjct: 1095 ------HQQSHQESARDWSGGRSGR----------SGSFIYQVSTHE-------QSESAH 1131
Query: 316 VSPRILTASQSRSNVPSASEVPDNRASEASQ-------GFRFLRRRWGLSSLSHNHSSES 368
R T + S+ A + + AS+ Q G R R+ S + S S
Sbjct: 1132 GRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHS 1191
Query: 369 DSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRES 428
S + + S+GR+ S R S R+ +D+ S + + SR H +
Sbjct: 1192 GSHHSHTTSQGRSDASHGQSGSR-------SASRQTRKDKQSGDGSRHSGSRHHEAASWA 1244
Query: 429 NEVVHLE-AQNDPLGAAANRPQASAASSSATTGGSTSDS 466
+ H + Q G+ +R Q S+ S + + + DS
Sbjct: 1245 DSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDS 1283
Score = 56.6 bits (135), Expect = 8e-08
Identities = 100/435 (22%), Positives = 162/435 (37%), Gaps = 63/435 (14%)
Query: 26 SGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQ 83
SG R +S + S D S S + S A +S ES ++ +R + +
Sbjct: 1535 SGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSV 1594
Query: 84 QRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRER 143
+D DS+ + SA RN + + S S+ PRS S G R
Sbjct: 1595 SQDRDSEGHSEDSERRSESASRN---HYGSAREQSRHGSRNPRSHQEDRASHGHSAESSR 1651
Query: 144 RDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRV-PSYSQGARPKENSMSTLQLNTSSTN 202
+ R ++S SG SS Q R P G+R ++++ S+ T
Sbjct: 1652 QSGTRHAETS----------SGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRR- 1700
Query: 203 HQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVS 262
+ +++ +R S S S E S S+TQ ++ + S R S
Sbjct: 1701 -----QDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQS 1755
Query: 263 SQRP-------FQESSDNE-------------GRRTTRRLLSRIASSMSSTF-------- 294
+R +Q S+ + GR+ +R +R +S S++
Sbjct: 1756 GERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRG 1815
Query: 295 ---FSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVP---SASEVPDNRASEASQGF 348
SR Q S +S++S S T SQ RS+V S S + Q
Sbjct: 1816 HPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSG 1875
Query: 349 RFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDE 408
R S H SS +DS +Q +G+++GP S RN+ + + +G E
Sbjct: 1876 DGSRHS---GSRHHEASSRADSSRHSQVGQGQSSGPRTS---RNQGSSVSQDSDSQGHSE 1929
Query: 409 SSRIPTSDTSSRSHI 423
S S ++SR+H+
Sbjct: 1930 DSE-RWSGSASRNHL 1943
Score = 55.5 bits (132), Expect = 2e-07
Identities = 112/454 (24%), Positives = 160/454 (35%), Gaps = 100/454 (22%)
Query: 21 SARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRS 80
SA SG RGSS + +S S DS+ QS SA A P Q S E +G S
Sbjct: 1380 SAVRDSGHRGSSGSQVTNSEGHSE--DSDTQSVSAHGQAGPHQQ---SHKESARGQSGES 1434
Query: 81 QNQQRD---HDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGT 137
+ R S + T+ T+ G RH Q SS G
Sbjct: 1435 SGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGS--------RHEQARNSSRHSASQDGQ 1486
Query: 138 DLMRERRDLER--RTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQ 195
D +R R R S +D S SG + + Q R + + P+
Sbjct: 1487 DTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRS------- 1539
Query: 196 LNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIIS 255
+SR +RN +S SR +S SR P
Sbjct: 1540 ------------------ASRQTRNEEQSGDGSR--------------HSGSRHHEP--- 1564
Query: 256 NSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSY 315
S R SS+ ++ G +T+RR SS+S S S+DS S N Y
Sbjct: 1565 -STRAGSSRHSQVGQGESAGSKTSRRQ----GSSVSQDRDSEGHSEDSERRSESASRNHY 1619
Query: 316 VSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQ 375
S R QSR + ++RAS H HS+ES ++ +
Sbjct: 1620 GSAR----EQSRHGSRNPRSHQEDRAS-------------------HGHSAESSRQSGTR 1656
Query: 376 ESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLE 435
+E + G SS + R +P R R + S +D+S+ S RR+ + VV
Sbjct: 1657 HAETSSGGQAASSQEQARSSP---GERHGSRHQQS----ADSSTDSGTGRRQDSSVV--- 1706
Query: 436 AQNDPLGAAANRPQASAASSSATTGGSTSDSAQG 469
D ++ QAS + + + S SA G
Sbjct: 1707 --GDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
Score = 53.5 bits (127), Expect = 6e-07
Identities = 112/461 (24%), Positives = 167/461 (36%), Gaps = 74/461 (16%)
Query: 21 SARMMSGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARS 78
++R SGSR +S + S D S S + S A S A +SE ++ +R
Sbjct: 2827 ASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRR 2886
Query: 79 RSQNQQRDHDSKRPKLSCTNCTTSAGRN-VGNGLNTLSDSSWRHSQVPRSSSMVLGSFGT 137
+ + +D DS+ + SA RN G+ L D S RH PRS G
Sbjct: 2887 QGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGS-RH---PRSHQEDRAGHGH 2942
Query: 138 DLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLN 197
R+ R T +S SG SS+ Q R + E S Q +
Sbjct: 2943 SADSSRQSGTRHTQTS----------SGGQAASSHEQAR-------SSAGERHGSHHQQS 2985
Query: 198 TSSTNHQLPSEHQTILSSRDS--RNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIIS 255
S+ H Q + RDS R S S E S S+TQ +S
Sbjct: 2986 ADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQS-------------VS 3032
Query: 256 NSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSY 315
+ S Q+ QES+ T S S +F + S+ + SE+S+
Sbjct: 3033 AHGQAGSHQQSHQESARGRSGET---------SGHSGSFLYQVSTHE-------QSESSH 3076
Query: 316 VSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLR-----RRWGLSSLSHNHSSESD- 369
T + S A + +R S + G +R R G H HS +S
Sbjct: 3077 GWTGPSTRGRQGSRHEQAQD--SSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSG 3134
Query: 370 ---SENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRR 426
S + + S+GR+ S R S R +E S + + SR H
Sbjct: 3135 HSGSHHSHTTSQGRSDASRGQSGSR-------SASRTTRNEEQSGDSSRHSVSRHHEAST 3187
Query: 427 ESNEVVHLEA-QNDPLGAAANRPQASAASSSATTGGSTSDS 466
++ H +A Q G+ +R Q S+ S + + G + DS
Sbjct: 3188 HADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS 3228
Score = 53.1 bits (126), Expect = 8e-07
Identities = 109/499 (21%), Positives = 183/499 (36%), Gaps = 84/499 (16%)
Query: 26 SGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQ 83
SGSR +S S D S S + ++ A +S +S ++ +R + +
Sbjct: 1211 SGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSV 1270
Query: 84 QRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRER 143
+D DS+R + SA RN S RH
Sbjct: 1271 SQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHP--------------------- 1309
Query: 144 RDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGAR--PKENSMSTLQLNTSST 201
+ +S + D S +SG T S + S + AR P E S Q + S+
Sbjct: 1310 -GFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSS 1368
Query: 202 NHQLPSEHQTILSSRDS--RNSLRSNFSSRESESSRSNTQPGFSY--------------- 244
H Q + RDS R S S ++ E S S+TQ ++
Sbjct: 1369 RHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESAR 1428
Query: 245 -----SSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSST------ 293
SS R + + S S Q + GR+ +R +R +S S++
Sbjct: 1429 GQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDT 1488
Query: 294 -----FFSRRSSQDSLNTRSLNS------ENSYVSPRILT-ASQSRSNVPSASEVPDNRA 341
SR Q S + +S++ +S+ +P+ + AS +S SAS N
Sbjct: 1489 IRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNE- 1547
Query: 342 SEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRR 401
++ G R S H S+ + S +Q +G + G S + R + + + R
Sbjct: 1548 EQSGDGSRH------SGSRHHEPSTRAGSSRHSQVGQGESAG---SKTSRRQGSSVSQDR 1598
Query: 402 RREGRDESSRIPTSDTSSRSHI--FRRES-----NEVVHLEAQNDPLGAAANRPQASAAS 454
EG E S S+++SR+H R +S N H E + +A + Q+
Sbjct: 1599 DSEGHSEDSE-RRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRH 1657
Query: 455 SSATTGGSTSDSAQGGRNT 473
+ ++GG + S + R++
Sbjct: 1658 AETSSGGQAASSQEQARSS 1676
Score = 50.4 bits (119), Expect = 5e-06
Identities = 110/463 (23%), Positives = 168/463 (36%), Gaps = 46/463 (9%)
Query: 22 ARMMSGSRGSSLNDTYHSRDSSFRL-DSEYQSTSASASASPFQSAWYSE-SEITQGARSR 79
+R G S +N + H S L +S + S + S +SE SE G+ SR
Sbjct: 260 SRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASR 319
Query: 80 SQNQ---QRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFG 136
+ + ++ D R S S G + +DSS R S + + G
Sbjct: 320 NHHGSAWEQSRDGSRHPRSHDEDRASHGHS--------ADSS-RQSGTRHAETSSRGQTA 370
Query: 137 TDLMRERRDLERRTDSSISNLMDYSHRS--GDFTTSSYVQDRVPSYSQGARPKENSMSTL 194
+ + R R S D S S G SS V DR S G++ +
Sbjct: 371 SSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRGSSGSQASD------ 424
Query: 195 QLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSS----SRDE 250
S H S+ Q++ S + LR S +ES RS + G S SS S E
Sbjct: 425 -----SEGHSENSDTQSV--SGHGKAGLRQQ-SHQESTRGRSGERSGRSGSSLYQVSTHE 476
Query: 251 APIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSM--SSTFFSRRSSQDSLNTRS 308
P ++ R +S Q S + R ++R S+ SR Q S + +S
Sbjct: 477 QPDSAHG-RTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
Query: 309 LNSENSYVSPRILTASQSRSNVP---SASEVPDNRASEASQGFRFLRRRWGLSSLSHNHS 365
+N S T SQ RS+ S S + Q R S H S
Sbjct: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS---GSRHHEAS 592
Query: 366 SESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFR 425
S++DS +Q +G+++GP S RN+ + + +G E S + S H
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTS---RNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSA 649
Query: 426 RESNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQ 468
+E + ++ A + A ++ S T S S Q
Sbjct: 650 QEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQ 692
Score = 49.3 bits (116), Expect = 1e-05
Identities = 100/383 (26%), Positives = 144/383 (37%), Gaps = 36/383 (9%)
Query: 10 RRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSE 69
R + + SA SG RGSS + S S DS+ QS SA A P Q S
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSE--DSDTQSVSAHGQAGPHQQ---SH 3692
Query: 70 SEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSS 129
E T+G RS + S ++S + SA G S RH Q SS
Sbjct: 3693 QESTRG---RSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGS--RHEQARDSSR 3747
Query: 130 MVLGSFGTDLMRERRDLER--RTDSSISNLMDYSHRSGDFTTSSYVQDRV-PSYSQ-GAR 185
G D +R R R S +D S SG + + Q R S+ Q G+R
Sbjct: 3748 HSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSR 3807
Query: 186 PKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYS 245
+ + + H H+ +S + +S S ES SR + + G S S
Sbjct: 3808 SASRETRNEEQSGDGSRHSGSRHHE---ASTQADSSRHSQSGQGESAGSRRSRRQGSSVS 3864
Query: 246 SSRDEAPIISNSE-RVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSL 304
D +SE R S+ R SS + R +R S + S S S S
Sbjct: 3865 QDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSST 3924
Query: 305 -----NTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSS 359
+ SL+ +++Y S QSR + S+S + SE ++ R+ G S
Sbjct: 3925 AKEHGHFSSLSQDSAYHS-----GIQSRGSPHSSSSY--HYQSEGTE------RQKGQSG 3971
Query: 360 LSHNHSSESDSENFNQESEGRNT 382
L H S ++ ES R++
Sbjct: 3972 LVWRHGSYGSADYDYGESGFRHS 3994
Score = 48.5 bits (114), Expect = 2e-05
Identities = 99/446 (22%), Positives = 154/446 (34%), Gaps = 76/446 (17%)
Query: 31 SSLNDTYHSRDSSF-RLDSEY-QSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHD 88
S + ++HS +S R D+ + QS S SAS + G+R + Q D
Sbjct: 539 SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSS 598
Query: 89 SKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLER 148
+ RN G+ ++ SDS R S + + RD R
Sbjct: 599 RHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSR 658
Query: 149 RTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSE 208
S + + H + S G R +NS S Q S
Sbjct: 659 HPRSHHEDRAGHGHSADS------------SRKSGTRHTQNSSS----------GQAASS 696
Query: 209 HQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQ 268
H+ SS R+ R S +S S S T G + S+ RD S+ + S+
Sbjct: 697 HEQARSSAGERHGSRHQLQSADS-SRHSGTGHGQASSAVRDSGHRGSSGSQATDSE-GHS 754
Query: 269 ESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRS 328
E SD + S ++S Q+S RS +SR
Sbjct: 755 EDSDTQS-----------VSGHGQAGHHQQSHQESARDRS--------------GERSRR 789
Query: 329 NVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSS 388
+ +V ++ SE+S G + G+ SH H D+ + +G++T
Sbjct: 790 SGSFLYQVSTHKQSESSHG--WTGPSTGVRQGSH-HEQARDNSRHSASQDGQDT------ 840
Query: 389 SLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAAANRP 448
R P SRR R+G + S S H H +Q + A+R
Sbjct: 841 ---IRGHPGSSRRGRQGSHHEQSVDRSGHSGSHH---------SHTTSQG---RSDASRG 885
Query: 449 QASAASSSATTGGSTSDSAQGGRNTG 474
Q+ + S+S TT + S G R++G
Sbjct: 886 QSGSRSASRTT-RNEEQSRDGSRHSG 910
Score = 47.8 bits (112), Expect = 4e-05
Identities = 97/443 (21%), Positives = 166/443 (37%), Gaps = 31/443 (6%)
Query: 38 HSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCT 97
HS DSS + + + S+S A ++ + ++ + G R S++Q + DS R +
Sbjct: 672 HSADSSRKSGTRHTQNSSSGQA----ASSHEQARSSAGERHGSRHQLQSADSSRHSGTGH 727
Query: 98 NCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNL 157
+SA R+ G+ ++ S ++ S + + G ++ E D S
Sbjct: 728 GQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRS---- 783
Query: 158 MDYSHRSGDF--TTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSS 215
+ S RSG F S++ Q G S + ++ H + Q +
Sbjct: 784 GERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRG 843
Query: 216 RDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNE- 274
+S R S +S + G +S + + S++ R S R ++ NE
Sbjct: 844 HPG-SSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGR--SDASRGQSGSRSASRTTRNEE 900
Query: 275 -GRRTTRRLLSRIASSMSSTFFSRRS------SQDSLNTRSLNSENSYVSPRILTASQSR 327
R +R SR + S SR S S+ S +R S S S + S
Sbjct: 901 QSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSE 960
Query: 328 SNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLS 387
SAS A E S+ R H HS++S ++ +E + G S
Sbjct: 961 RWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAAS 1020
Query: 388 SSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAAANR 447
S + R +P R R + S +D+S S I RR+++ V + G++ ++
Sbjct: 1021 SHEQARSSP---GERHGSRHQQS----ADSSRHSGIPRRQASSAVR---DSGHWGSSGSQ 1070
Query: 448 PQASAASSSATTGGSTSDSAQGG 470
S S + S S Q G
Sbjct: 1071 ASDSEGHSEESDTQSVSGHGQDG 1093
Score = 47.4 bits (111), Expect = 5e-05
Identities = 106/494 (21%), Positives = 171/494 (34%), Gaps = 64/494 (12%)
Query: 21 SARMMSGSRGSSLN--DTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARS 78
++R SGSR +S D S D S S + S+ A +S +S + +R
Sbjct: 2179 ASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRP 2238
Query: 79 RSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTD 138
R + +D DS+ + SA RN S RH PRS G
Sbjct: 2239 RGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH---PRSHHEDRAGHGHS 2295
Query: 139 LMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNT 198
R+ ++S SG SS+ Q R + E S Q +
Sbjct: 2296 AESSRQSGTHHAENS----------SGGQAASSHEQAR-------SSAGERHGSHHQQSA 2338
Query: 199 SSTNHQLPSEHQTILSSRDS--RNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN 256
S+ H Q + RDS R S S S E S S+TQ ++ +
Sbjct: 2339 DSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE 2398
Query: 257 SERVVSSQR------------PFQESSDNEGRRTT----RRLLSRIASSMSSTFFSRRSS 300
S R S+ R ++S GR T R+ + SS + +
Sbjct: 2399 STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEG 2458
Query: 301 QDSLN----TRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRW- 355
QD+++ + S + S+ + + S S+ + + AS G R R+
Sbjct: 2459 QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTR 2518
Query: 356 ----------GLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREG 405
S H SS +DS +Q +G++ GP S RN + +G
Sbjct: 2519 NDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTS---RNWGSSFSQDSDSQG 2575
Query: 406 RDESSRIPTSDTSSRSHIFRRES------NEVVHLEAQNDPLGAAANRPQASAASSSATT 459
E S + S H +E + H E + +A + Q+ + ++
Sbjct: 2576 HSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSS 2635
Query: 460 GGSTSDSAQGGRNT 473
GG + S + R++
Sbjct: 2636 GGQAASSHEQARSS 2649
Score = 43.9 bits (102), Expect = 5e-04
Identities = 110/514 (21%), Positives = 176/514 (34%), Gaps = 82/514 (15%)
Query: 22 ARMMSGSRGSS--LNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSR 79
+R SGSR S + S D S S + S+ A +S +S + +R++
Sbjct: 1855 SRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQ 1914
Query: 80 SQNQQRDHDSKRPKLSCTNCTTSAGRN-VGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTD 138
+ +D DS+ + SA RN +G+ D S RH P S G
Sbjct: 1915 GSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGS-RH---PGSHHEDRAGHGHS 1970
Query: 139 LMRERRDLERRTDSSISNLMDYSHRSGDFTTSS------YVQDRVPSYSQGARPKENSMS 192
R+ R T+SS SH + +Q S G + S +
Sbjct: 1971 ADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSA 2030
Query: 193 TLQLN---------TSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPG-F 242
+ S H S+ Q++ + + +S+ S +S S+ + G F
Sbjct: 2031 VRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSF 2090
Query: 243 SYSSSRDEAPIISNSERVVSS-----------QRPFQESSDNEGRRTTRRLLSRIASSMS 291
Y S E ++ + S+ Q + S+ EG+ T R
Sbjct: 2091 LYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIR----------G 2140
Query: 292 STFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVP---SASEVPDNRASEASQGF 348
SR Q S +S++ S T SQ RS+ S S + + Q
Sbjct: 2141 HPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSG 2200
Query: 349 RFLRRRWGLSSLSHNH--SSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGR 406
R S SH+H SS +DS + +G+++GP S R R + + EG
Sbjct: 2201 DGSRH-----SGSHHHEASSWADSSRHSLVGQGQSSGPRTS---RPRGSSVSQDSDSEGH 2252
Query: 407 DESSRIPTSDTSSRSHIFRRE-------------------------SNEVVHLEAQNDPL 441
E S + S H +E S + A+N
Sbjct: 2253 SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSG 2312
Query: 442 GAAANRPQASAASSSATTGGSTSDSAQGGRNTGI 475
G AA+ + + +S+ G SA R++GI
Sbjct: 2313 GQAASSHEQARSSAGERHGSHHQQSADSSRHSGI 2346
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 65.5 bits (158), Expect = 2e-10
Identities = 80/348 (22%), Positives = 142/348 (40%), Gaps = 27/348 (7%)
Query: 3 SKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPF 62
S+ S + IS+ +S S S ++ + S +S +S+ +TS+ AS
Sbjct: 93 SEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGAS---- 148
Query: 63 QSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHS 122
+A S+S T S + N + + TTS+G + + + SS +
Sbjct: 149 -TATNSDSSTTSSEASTATNSE-------------SSTTSSGASTATNSESSTVSSRAST 194
Query: 123 QVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQ 182
SS T E R ++ ++ + S S +T++ + PS
Sbjct: 195 ATNSESSTTSSGASTATNSESRTTSNGAGTATNS--ESSTTSSGASTATNSESSTPSSGA 252
Query: 183 GARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGF 242
G S +T ++TN + + I + +S +S S+ ++ + S S T G
Sbjct: 253 GTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGA 312
Query: 243 SYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQD 302
+ +++ D + S + +S + S+ + G T S SS +ST + SS
Sbjct: 313 NTATNSDSSTTSSGASTATNS----ESSTTSSGASTATNSESSTTSSGASTATNSGSSTT 368
Query: 303 SLNT-RSLNSENSYVSPRILTASQSRSNVPS--ASEVPDNRASEASQG 347
S T + NSE+S VS TA+ S S+ S AS ++ +S S G
Sbjct: 369 SSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSG 416
Score = 57.8 bits (138), Expect = 3e-08
Identities = 75/376 (19%), Positives = 142/376 (37%), Gaps = 33/376 (8%)
Query: 13 SVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEI 72
S +S S S ++ + + S ++S +SE +TS+ AS +A SES
Sbjct: 133 STATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGAS-----TATNSESST 187
Query: 73 TQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVL 132
S + N + S + + + + G N+ S ++ + +S
Sbjct: 188 VSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESST 247
Query: 133 GSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMS 192
S G + + + + S S +T + + PS S +
Sbjct: 248 PSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESST 307
Query: 193 TLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAP 252
T ++TN + ++ +S +S S+ +S + S S T G S +++ +
Sbjct: 308 TSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSST 367
Query: 253 IISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSE 312
S + +S+ S ++S S+ S S+ S + + NSE
Sbjct: 368 TSSGTSTATNSES------------------STVSSGASTATTSESSTTSSGASTATNSE 409
Query: 313 NSYVSPRILTASQSRSNVPS--ASEVPDNRASEASQGFRFLRRRWGLSSLSHNH-SSESD 369
+S VS TA+ S S+ S A+ ++ +S S G G ++L+ H +S S
Sbjct: 410 SSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGS-------GTAALTGMHTTSHSA 462
Query: 370 SENFNQESEGRNTGPW 385
S ++ G + PW
Sbjct: 463 STAVSEAKPGGSLVPW 478
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/327 (23%), Positives = 134/327 (40%), Gaps = 46/327 (14%)
Query: 214 SSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDN 273
+S ++ +S+ S+ +S + S S T G S +++ + + SN +V++ SS
Sbjct: 29 TSANTGSSVISSGASTATNSGSSVTSSGVS-TATISGSSVTSNGVSIVTNSEFHTTSSG- 86
Query: 274 EGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPS- 332
S+ +++ FS SS S+ T NSE+S S TA+ S S+ PS
Sbjct: 87 -------------ISTATNSEFSTVSSGISIAT---NSESSTTSSGASTATNSESSTPSS 130
Query: 333 -ASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSE-NFNQESEGRNTGPWLSSSL 390
AS ++ +S S G S+ +++ SS + SE + SE T S++
Sbjct: 131 GASTATNSDSSTTSS---------GASTATNSDSSTTSSEASTATNSESSTTSSGASTAT 181
Query: 391 RNRCTPLFSRRRREGRDESSRI---PTSDTSSRSHIFRRESNEVVHLEAQNDPLGA--AA 445
+ + + SR ESS ++ T+S S + + E+ GA A
Sbjct: 182 NSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTAT 241
Query: 446 NRPQASAASSSATTGGSTSDSAQGGRNTGI--------SGILPGSLFRFAVPPALGSNLT 497
N ++ +S + T S S + G T SGI + + P + + T
Sbjct: 242 NSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTAT 301
Query: 498 DNVMITVDIIPSGWNSADGKSDKTKSA 524
++ T SG N+A T S+
Sbjct: 302 NSESSTTS---SGANTATNSDSSTTSS 325
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 64.3 bits (155), Expect = 4e-10
Identities = 104/475 (21%), Positives = 186/475 (39%), Gaps = 77/475 (16%)
Query: 2 ESKPSRIPRRISVQPSSSLSARMMSG------SRGSSLNDTYHSRDSSFRLDSEYQSTSA 55
++K RI ++ S S + RM S SR SSL+ + S+ + D + QS+
Sbjct: 453 QTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLT 512
Query: 56 SASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLS 115
+S ++S +S+S +RSR+ ++ H R K + ++ +G
Sbjct: 513 HSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSK---SRSSSKSGHRK-------- 561
Query: 116 DSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQD 175
R S+ PR ++ L ++ + + R T + N++ + +
Sbjct: 562 ----RASKSPRKTASQL----SENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDS 613
Query: 176 RVPS-YSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSS----------------RDS 218
PS + G +P + S +Q + T H LP + L++ +S
Sbjct: 614 PPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSES 673
Query: 219 RNSLRSNFSSRESESS-----RSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQES--- 270
S S +S R SESS RS+ +S S +R + S+S S R +
Sbjct: 674 DQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYS 733
Query: 271 --------------SDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYV 316
S ++GRR RRL S + S SS+ +L+++ + +
Sbjct: 734 DHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSS 793
Query: 317 SPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNH------SSESDS 370
R + S+S + S SE +A++++Q + + G +HN +S S
Sbjct: 794 CVRKYSESRSSLDYSSDSEQSSVQATQSAQE----KEKQGQMERTHNKQEKNRGEEKSKS 849
Query: 371 ENFNQESEGRNTGPWLSSSLRNRCTPL---FSRRRREGRDESSRIPTSDTSSRSH 422
E S+ R LS LRN P ++ + + S R T ++ + SH
Sbjct: 850 ERECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSH 904
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/197 (25%), Positives = 78/197 (39%), Gaps = 28/197 (14%)
Query: 193 TLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAP 252
T +LN N + S+ QT DS++ S S+ SR T+ SYS SR +
Sbjct: 1284 TARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTR-SVSYSHSRSRSR 1342
Query: 253 IISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNS- 311
++S R S R + GR +R SS++ S +S + S +RS +S
Sbjct: 1343 SSTSSYRSRSYSRSRSRGWYSRGRTRSR----------SSSYRSYKSHRTSSRSRSRSSS 1392
Query: 312 ------ENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHS 365
SY + S+SRS R+ +G + RR S S+
Sbjct: 1393 YDPHSRSRSYTYDSYYSRSRSRSR--------SQRSDSYHRGRSYNRR--SRSCRSYGSD 1442
Query: 366 SESDSENFNQESEGRNT 382
SESD + S ++
Sbjct: 1443 SESDRSYSHHRSPSESS 1459
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/240 (23%), Positives = 91/240 (37%), Gaps = 25/240 (10%)
Query: 7 RIPRRI-SVQPSSSLSARMMSGSRGSSLNDTY---HSRDSSFRLDSEYQST---SASASA 59
R RR+ S +S+S + S S +L+ Y R S R SE +S+ S+ +
Sbjct: 754 RAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQ 813
Query: 60 SPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSW 119
S Q+ ++ + QG R+ N+Q + + S C S R + L+
Sbjct: 814 SSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLS----DHL 869
Query: 120 RHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPS 179
R+ P+ + GS RD+ + + + SH S D D
Sbjct: 870 RNGSKPKRKNYA-GSKWDSESNSERDVTKNSKND-------SHPSSDKEEGEATSDSESE 921
Query: 180 YSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQ 239
S E + SSTN LP ++ SS+ ++ S S SE++R Q
Sbjct: 922 VS------EIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQ 975
Score = 32.3 bits (72), Expect = 1.5
Identities = 48/178 (26%), Positives = 73/178 (41%), Gaps = 16/178 (8%)
Query: 31 SSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSK 90
SS ++ SRD DS+ +S S S S S +S + S +RSRS++ + S+
Sbjct: 1296 SSSDEQTPSRDD----DSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSR 1351
Query: 91 RPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRT 150
S + S GR + S S R S RS S + R
Sbjct: 1352 SYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRS-------SSYDPHSRSRSYTY 1404
Query: 151 DSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSE 208
DS S RS + SY + R SY++ +R + S + + S ++H+ PSE
Sbjct: 1405 DSYYSRSRS---RSRSQRSDSYHRGR--SYNRRSRSCRSYGSDSESDRSYSHHRSPSE 1457
Score = 32.3 bits (72), Expect = 1.5
Identities = 31/111 (27%), Positives = 49/111 (44%), Gaps = 14/111 (12%)
Query: 26 SGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASP-----FQSAWYSESEITQGARSRS 80
S SRG SR SS+R ++++S S S S +S Y+ +RSRS
Sbjct: 1356 SRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRS 1415
Query: 81 QNQQRD--HDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSS 129
++Q+ D H + +C + G ++ SD S+ H + P SS
Sbjct: 1416 RSQRSDSYHRGRSYNRRSRSCRS-------YGSDSESDRSYSHHRSPSESS 1459
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 59.7 bits (143), Expect = 9e-09
Identities = 104/424 (24%), Positives = 158/424 (37%), Gaps = 57/424 (13%)
Query: 2 ESKPSRIPRRISVQPSSSLSARMM---SGSRGSSLNDTYHSRDSSFRLDSEYQSTSASAS 58
E++ SR P + +Q LSAR + SGS T +S EY S + ++S
Sbjct: 235 EAQSSRPPSQ-PLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSS 293
Query: 59 ASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSS 118
Q++ +G+ S ++ R+ +S S + TTS+ +N G L LS +S
Sbjct: 294 PPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTS 353
Query: 119 -WRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRV 177
R S+ +S + E + S + + S G +SSY R
Sbjct: 354 RGRESRGFQSPCLECA-------------EVKKSSLVPSTARSSPMKGCSRSSSYASTRS 400
Query: 178 PSY-SQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRS 236
S+ S+ P+ + T +TSS SR S +S S S SSRS
Sbjct: 401 SSHSSRSPNPRASPRYTQSRSTSSEKRSY---------SRSPSYSSKSGKRSPPSRSSRS 451
Query: 237 NTQPGFS-YSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFF 295
P +S YS SR+ P S ++S E R RR S S
Sbjct: 452 RRSPSYSRYSPSRERDPKYSE-----------KDSQQRERERARRR-----RRSYSPMRK 495
Query: 296 SRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRW 355
RR S L R + S P + S ++ S S + +S ++ R
Sbjct: 496 RRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSAS-------RS 548
Query: 356 GLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTS 415
S S + S + S R+ P S R+R SR R R +S ++
Sbjct: 549 YSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSR-----SRSRSRSRSQSRSYSSA 603
Query: 416 DTSS 419
D+ S
Sbjct: 604 DSYS 607
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 55.1 bits (131), Expect = 2e-07
Identities = 76/311 (24%), Positives = 119/311 (38%), Gaps = 14/311 (4%)
Query: 26 SGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQR 85
S S S + + HSR S R S S S S S S S S+S +RSRS+ ++
Sbjct: 188 SRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKS 247
Query: 86 DHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRD 145
SK S ++ SAG++ + + + V + S + R
Sbjct: 248 RSPSKEKSRSRSH---SAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRS 304
Query: 146 LERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQL 205
ERR + S G S Q R S S+G + + + +
Sbjct: 305 QERRVEEEKRG----SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRS 360
Query: 206 PSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSE-----RV 260
E ++ SR R S R+S++ S + S+ +P S S+ +
Sbjct: 361 REESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKS 420
Query: 261 VSSQRPFQESSDNEG--RRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSP 318
SSQR + S+N G + T R S S + SR S+ + TRS + S +
Sbjct: 421 ESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 480
Query: 319 RILTASQSRSN 329
R + S+SRS+
Sbjct: 481 RSPSRSRSRSH 491
>gi|8923613 membrane-associated RING-CH protein I [Homo sapiens]
Length = 272
Score = 53.5 bits (127), Expect = 6e-07
Identities = 24/59 (40%), Positives = 34/59 (57%), Gaps = 9/59 (15%)
Query: 550 DLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCK 608
D+CRIC S L I PC+CTG+L++VHQ C+ +W+++ CELCK
Sbjct: 61 DICRICHCEGDEESPL-ITPCRCTGTLRFVHQSCLHQWIKS--------SDTRCCELCK 110
>gi|50539414 cellular modulator of immune recognition isoform 7
[Homo sapiens]
Length = 291
Score = 53.1 bits (126), Expect = 8e-07
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 9/59 (15%)
Query: 550 DLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCK 608
D+CRIC S L I PC CTGSL +VHQ C+++W+++ CELCK
Sbjct: 78 DICRICHCEGDDESPL-ITPCHCTGSLHFVHQACLQQWIKS--------SDTRCCELCK 127
>gi|50539412 cellular modulator of immune recognition isoform 6
[Homo sapiens]
Length = 291
Score = 53.1 bits (126), Expect = 8e-07
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 9/59 (15%)
Query: 550 DLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCK 608
D+CRIC S L I PC CTGSL +VHQ C+++W+++ CELCK
Sbjct: 78 DICRICHCEGDDESPL-ITPCHCTGSLHFVHQACLQQWIKS--------SDTRCCELCK 127
>gi|50539410 cellular modulator of immune recognition isoform 8
[Homo sapiens]
Length = 291
Score = 53.1 bits (126), Expect = 8e-07
Identities = 25/59 (42%), Positives = 33/59 (55%), Gaps = 9/59 (15%)
Query: 550 DLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCK 608
D+CRIC S L I PC CTGSL +VHQ C+++W+++ CELCK
Sbjct: 78 DICRICHCEGDDESPL-ITPCHCTGSLHFVHQACLQQWIKS--------SDTRCCELCK 127
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 52.0 bits (123), Expect = 2e-06
Identities = 115/461 (24%), Positives = 175/461 (37%), Gaps = 83/461 (18%)
Query: 9 PRRISVQPSS-SLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASA-------SAS 60
PR S PSS L+ + ++ R S +++ + + R +S S S+ SAS
Sbjct: 1493 PRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSAS 1552
Query: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
P Q S+S A++R+ +QR P++ + S R+ + D +
Sbjct: 1553 P-QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD-SKSRLSPRRSRSGSSPEVKD---K 1607
Query: 121 HSQVPRSSSMVLGSFGTDLMRER-----RDLERRTDSSISNLMDYSHRSGDFTTSSYVQD 175
PR+ S G+D E R L RR+ S S+ G +T S +
Sbjct: 1608 PRAAPRAQS------GSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661
Query: 176 RVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESS- 234
P S+ AR S S+ + T S + P ++ SS + R + SR + SS
Sbjct: 1662 --PPKSRTAR--RGSRSSPEPKTKS---RTPPRRRSSRSSPELTRKARLSRRSRSASSSP 1714
Query: 235 --RSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSS 292
RS T P S S VSS P ++S + RR+ ASS +
Sbjct: 1715 ETRSRTPPRHRRSPS-------------VSSPEPAEKSRSSRRRRS--------ASSPRT 1753
Query: 293 TFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLR 352
SRR S R L S S R T + R + +S+ R + R R
Sbjct: 1754 KTTSRRGRSPSPKPRGLQRSRSR-SRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTR 1812
Query: 353 RRWGLSSL-SHNHSSESDSENFNQESEGR---------------NTGPWLSSSLRNRCTP 396
RR G S S + + + S ++ GR + PW S R+R +P
Sbjct: 1813 RRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS--RSRASP 1870
Query: 397 LFSRR---------RREGRDESSRIPTSDTSSRSHIFRRES 428
RR RR R +S + + SR+ + RR S
Sbjct: 1871 ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911
Score = 38.9 bits (89), Expect = 0.016
Identities = 90/372 (24%), Positives = 127/372 (34%), Gaps = 26/372 (6%)
Query: 10 RRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASA-------SPF 62
RR+ S + + R S SR + SR +R Q S S SP
Sbjct: 479 RRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQ 538
Query: 63 QSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHS 122
+ W + RSRS + R H + T A R G + S
Sbjct: 539 RPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARR--GRSRSRTPARRRSRS 596
Query: 123 QVP---RSSSMVLGSFGTDLMRERRDLERRTDSSI---SNLMDYSHRSGDFTTSSYVQDR 176
+ P RS S G R RT S + S + RSG + + +
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRG 656
Query: 177 VPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESES-SR 235
AR + T + + + P+ S R RS R S SR
Sbjct: 657 RSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSR 716
Query: 236 SNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFF 295
+ + G S SSS + ++ R S+ P + S RR SR SS S
Sbjct: 717 TPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR------SRSLSSPRSKAK 770
Query: 296 SRRSSQDSLNTRS-LNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRR 354
SR S + SL+ S + S PR S+S S+ P A R S +S ++
Sbjct: 771 SRLSLRRSLSGSSPCPKQKSQTPPR---RSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKS 827
Query: 355 WGLSSLSHNHSS 366
S SH+ SS
Sbjct: 828 KTPSRQSHSSSS 839
Score = 37.4 bits (85), Expect = 0.048
Identities = 84/371 (22%), Positives = 132/371 (35%), Gaps = 61/371 (16%)
Query: 3 SKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLD-SEYQSTSASASASP 61
+ P + R S P S+ S M+ R S + S L ++ Q S SA
Sbjct: 2397 TSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFS 2456
Query: 62 FQS-AWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
QS +++ G++S S + T+SAG + NG+ ++
Sbjct: 2457 DQSRCLIAQTTPVAGSQSLSSG------------AVATTTSSAGDH--NGMLSVPAPGVP 2502
Query: 121 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSY 180
HS V + + L + ERR+ SS S+ S S ++SS S
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 181 SQGA---------------------------RPKENSMSTLQLNTSSTNHQLPSEHQTIL 213
S+G+ RP E + + + +SS++ S +
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622
Query: 214 SSRDSRNSLRSNFSSRESESSRSNTQPG--------FSYSSSRDEAPIISNSERVVSSQR 265
SS S +S S+ SS S SS S++ P +S + P R S ++
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP--PGERRSRSPRK 2680
Query: 266 PFQESSDN--------EGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVS 317
P D+ E RR + + R S SS SRR + + S S
Sbjct: 2681 PIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Query: 318 PRILTASQSRS 328
PR + SRS
Sbjct: 2741 PRPMRHRSSRS 2751
Score = 36.6 bits (83), Expect = 0.082
Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 25/154 (16%)
Query: 182 QGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPG 241
Q A+ + +S S+ ++SS++ SS S +S S SS +SE S QP
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSS-----------SSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 242 FSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQ 301
+ + V S P + + EGR R S SS+ S SS
Sbjct: 2574 VAL--------------KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSS 2619
Query: 302 DSLNTRSLNSENSYVSPRILTASQSRSNVPSASE 335
S ++ S +S +S S ++S S S+ PS ++
Sbjct: 2620 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK 2653
Score = 35.8 bits (81), Expect = 0.14
Identities = 103/434 (23%), Positives = 159/434 (36%), Gaps = 45/434 (10%)
Query: 6 SRIPRRISVQPSSSLSARMMSGS--RGSSLNDTYHSRDSSFRLDSEYQSTSA---SASAS 60
SR P+R S + R S S RG S HSR + R S ++ + S S +
Sbjct: 534 SRSPQRPGWSRSRNTQRRGRSRSARRGRS-----HSRSPATRGRSRSRTPARRGRSRSRT 588
Query: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
P + S + + +RSR+ ++ S+ P + T S R + S
Sbjct: 589 PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR-TRSPVRRRSRSRSPARRSGRS 647
Query: 121 HSQVP----RSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDR 176
S+ P RS S G R RR+ S S RS T + R
Sbjct: 648 RSRTPARRGRSRSRTPARRGRS---RSRTPARRSGRSRSRTPARRGRSRSRTPR---RGR 701
Query: 177 VPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRS 236
S S R + +S + + S ++ + ++ SR S+ RSN SS E + SR
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK------SRTSQRRSRSN-SSPEMKKSRI 754
Query: 237 NTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTR------RLLSRIASSM 290
+++ S SS R +A + R +S P + R +R + SR
Sbjct: 755 SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR 814
Query: 291 SSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNV---PSASE---VPDNRASEA 344
S + S Q S + +S P++ + + R P A+E P R+
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 345 SQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRRE 404
S L+ R HS S + S P SSS + + + S R+R
Sbjct: 875 SSPDPELKSR-----TPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRS 929
Query: 405 GRDESSRIPTSDTS 418
SS P+ TS
Sbjct: 930 HSGSSSPSPSRVTS 943
Score = 34.3 bits (77), Expect = 0.41
Identities = 62/244 (25%), Positives = 86/244 (35%), Gaps = 24/244 (9%)
Query: 218 SRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRR 277
SRN+ R SR + RS+++ + SR P R + R S RR
Sbjct: 545 SRNTQRRG-RSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRR 603
Query: 278 TTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVP-----S 332
+ R +R S S T RRS TRS S + +SRS P S
Sbjct: 604 SRSRTPARRGRSRSRTPARRRS-----RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS 658
Query: 333 ASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPWLSSSLRN 392
S P R S R RR G S S + + S G S SL
Sbjct: 659 RSRTPARRGRSRS---RTPARRSGRS------RSRTPARRGRSRSRTPRRGRSRSRSLVR 709
Query: 393 RCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHLEAQNDPLGAAANRPQASA 452
R +R GR SS S+ ++S +R S E + + + +R +S
Sbjct: 710 RGRSHSRTPQRRGRSGSS----SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765
Query: 453 ASSS 456
S +
Sbjct: 766 RSKA 769
Score = 32.7 bits (73), Expect = 1.2
Identities = 67/294 (22%), Positives = 110/294 (37%), Gaps = 32/294 (10%)
Query: 201 TNHQLPSEHQTILSSRDSRNSL---RSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNS 257
T+ ++P +S R S L RS SR ++ S SS +AP S
Sbjct: 2381 TSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLL 2440
Query: 258 ERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVS 317
R S+ ++ R + +A S S + S + T S N +S
Sbjct: 2441 PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLS-----SGAVATTTSSAGDHNGMLS 2495
Query: 318 PRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQES 377
S P AS ++ A+ RR SS S + SS S S + + S
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 378 EGRNTGPWLSSSLRNRC----------TPLFSRRRREGRDESSRIPTSDTSSRSHIFRRE 427
G ++ SSL + TP REGR P T ++ RR
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGR------PPEPTPAKRK--RRS 2607
Query: 428 SNEVVHLEAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPG 481
S+ + + ++++ +S++SSS+++ S+S S+ ++ S PG
Sbjct: 2608 SS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
>gi|33589846 membrane-associated ring finger (C3HC4) 6 [Homo
sapiens]
Length = 910
Score = 51.6 bits (122), Expect = 2e-06
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 9/63 (14%)
Query: 548 EGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELC 607
E D+CR+C+ + + L PC CTGS++++HQ+C+ +WL+ CELC
Sbjct: 5 EEDICRVCR-SEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKE--------YCELC 55
Query: 608 KEK 610
K +
Sbjct: 56 KHR 58
>gi|53729334 membrane-associated ring finger (C3HC4) 2 isoform 2
[Homo sapiens]
Length = 176
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 14/82 (17%)
Query: 526 SRDPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMK 585
SRD L + +L +G CRIC A + L+ PC CTG+L VH+ C++
Sbjct: 42 SRDGRLLSTVIRAL----DTPSDGPFCRICHEGA--NGECLLSPCGCTGTLGAVHKSCLE 95
Query: 586 KWLQAKINSGSSLEAVTTCELC 607
KWL + S CELC
Sbjct: 96 KWLSSSNTS--------YCELC 109
>gi|53729332 membrane-associated ring finger (C3HC4) 2 isoform 1
[Homo sapiens]
Length = 246
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 14/82 (17%)
Query: 526 SRDPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMK 585
SRD L + +L +G CRIC A + L+ PC CTG+L VH+ C++
Sbjct: 42 SRDGRLLSTVIRAL----DTPSDGPFCRICHEGA--NGECLLSPCGCTGTLGAVHKSCLE 95
Query: 586 KWLQAKINSGSSLEAVTTCELC 607
KWL + S CELC
Sbjct: 96 KWLSSSNTS--------YCELC 109
>gi|53729330 membrane-associated ring finger (C3HC4) 2 isoform 1
[Homo sapiens]
Length = 246
Score = 50.4 bits (119), Expect = 5e-06
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 14/82 (17%)
Query: 526 SRDPERLQKIKESLLLEDSEEEEGDLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMK 585
SRD L + +L +G CRIC A + L+ PC CTG+L VH+ C++
Sbjct: 42 SRDGRLLSTVIRAL----DTPSDGPFCRICHEGA--NGECLLSPCGCTGTLGAVHKSCLE 95
Query: 586 KWLQAKINSGSSLEAVTTCELC 607
KWL + S CELC
Sbjct: 96 KWLSSSNTS--------YCELC 109
>gi|30425370 membrane-associated ring finger (C3HC4) 3 [Homo
sapiens]
Length = 253
Score = 49.7 bits (117), Expect = 9e-06
Identities = 30/118 (25%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 490 PALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPSRDPERLQKIKESLLLEDSEEEEG 549
P + + T + V + + +G+ ++D + L + +L + S +
Sbjct: 10 PEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQ-SPFNDR 68
Query: 550 DLCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELC 607
+CRIC SS L+ PC+CTG+L +H+ C++ WL + S CELC
Sbjct: 69 PMCRICH--EGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTS--------YCELC 116
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 48.9 bits (115), Expect = 2e-05
Identities = 82/341 (24%), Positives = 125/341 (36%), Gaps = 23/341 (6%)
Query: 2 ESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASP 61
+ + S PR+ S + S + SR S N +RD S R S Y++ S S SP
Sbjct: 376 DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK---ARDRS-RSRSPYKARDRSRSRSP 431
Query: 62 FQSAWYSESEITQGAR----SRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDS 117
++ S S AR SRS N+ RDH R + + S + + L
Sbjct: 432 NKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSP 491
Query: 118 S----WRHSQVPRSSSMVLGSFGTDLMRERR-------DLERRTDSSISNLMDYSHRSGD 166
S R S+ P S + R+ R + +RR S + D S
Sbjct: 492 SKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSP 551
Query: 167 FTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNF 226
+ Q R PS + R + S S + S + +H S R
Sbjct: 552 SEEREHRQSRSPSKERDRR-RWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRA 610
Query: 227 SSRESESSRSNT-QPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSR 285
SS+E SRS T ++S SR + S+ V ++ S + R S+
Sbjct: 611 SSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSK 670
Query: 286 IASSMSSTFFS--RRSSQDSLNTRSLNSENSYVSPRILTAS 324
+S STF S + SQD + S+ + R ++S
Sbjct: 671 TSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSS 711
Score = 45.4 bits (106), Expect = 2e-04
Identities = 107/457 (23%), Positives = 155/457 (33%), Gaps = 62/457 (13%)
Query: 10 RRISVQPSSSLSARMMSGSRGSSLNDTYHSR-DSSFRLDSEYQSTSASASASPFQSAWYS 68
R + PSSS S + S R S + SR S R S + + ++ AS
Sbjct: 53 RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112
Query: 69 ESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSS 128
+ T +R R+ ++ SKR + ++ GR + T S+V +
Sbjct: 113 QRRGTH-SRGRTPGRRGSRSSKRSP----SRASTPGR-----IRTHGARPGMASRVRTPT 162
Query: 129 SMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHR------------------------- 163
S GS G R R R+DS NL S+R
Sbjct: 163 SQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTP 222
Query: 164 --------------SGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEH 209
S SY Q +PS + P E S N +ST + P H
Sbjct: 223 TGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSR-PQSH 281
Query: 210 QTILSSRDSRNSLRSNFSSR-ESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQ 268
S R SR+ + SR S S + N S + SR I+S R S+ +
Sbjct: 282 SQSRSPRRSRSGSQKRTHSRVRSHSWKRN----HSRARSRTRKGILSQMGRHSQSRSHSK 337
Query: 269 ESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENS--YVSPRILTASQS 326
S N+ RT RR S S S S S+ S R +S S R + S +
Sbjct: 338 GKSQNQS-RTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPN 396
Query: 327 RSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSEN--FNQESEGRNTGP 384
+ S S P N+A + S+ + R S S N + + + R+ P
Sbjct: 397 KQRDHSRSRSP-NKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP 455
Query: 385 WLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRS 421
+ +P +R R R S S S S
Sbjct: 456 NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492
Score = 40.4 bits (93), Expect = 0.006
Identities = 87/392 (22%), Positives = 123/392 (31%), Gaps = 68/392 (17%)
Query: 6 SRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSA 65
SR PRR S ++ S S S + R SS +S S S + S
Sbjct: 344 SRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR 403
Query: 66 WYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVP 125
S ++ +RSRS + RD R +C+ S S ++
Sbjct: 404 SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSR-------------SPYKARDRS 450
Query: 126 RSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGAR 185
RS S + + +R S S D+S + + R PS + R
Sbjct: 451 RSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCR 510
Query: 186 PKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYS 245
+S RD R S RS R+ SRS P
Sbjct: 511 QSRSSS----------------------KERDHRRS-RSPSKERQRRQSRS---PNKERD 544
Query: 246 SSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLN 305
S+ +P S +R ++S R RR S S +D
Sbjct: 545 RSQSRSP---------SEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSR 595
Query: 306 TRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHS 365
+RS N ++ Y PR + S+ S S P G S S S
Sbjct: 596 SRSPNKQSGYSRPR----ASSKEKAHSRSRTPSKE---------------GNHSQSRTSS 636
Query: 366 SESD-SENFNQESEGRNTGPWLSSSLRNRCTP 396
ESD S++ S P +SSL TP
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQNRTP 668
>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
Length = 1486
Score = 47.8 bits (112), Expect = 4e-05
Identities = 69/325 (21%), Positives = 117/325 (36%), Gaps = 41/325 (12%)
Query: 51 QSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNG 110
+ST S + P T+ A S S ++ P S + TT
Sbjct: 327 RSTPTSETTYPTSPTSTVTDSTTKIAYSTSMTGTLSTETSLPPTSSSLPTTETATTPMTN 386
Query: 111 LNTLSDSSWRHSQVPRSSSMVLGS--------FGTDLMRERRDLER--RTDSSISNLMDY 160
L T + HS SSS + + F + + R SS +N
Sbjct: 387 LVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTT 446
Query: 161 SHRSGDFT----TSSYVQDRVPSYSQGARPKENSMSTLQLNTSS------TNHQLPSEHQ 210
SHRS FT T+ PS++ E + + + TSS T+H S
Sbjct: 447 SHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTS 506
Query: 211 TILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN-------------- 256
+I ++ + +S S SS + + S++ P FS S + E P+ S
Sbjct: 507 SITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTS 566
Query: 257 ------SERVVSSQRPFQESSDNEGRRTTRRLLSRIASSM-SSTFFSRRSSQDSLNTRSL 309
+ + +++ + TT S S+ SST +S S+ + T
Sbjct: 567 HITPGLTSSITTTETTSHSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHF 626
Query: 310 NSENSYVSPRILTASQSRSNVPSAS 334
+ + V+P +T S +++P+ S
Sbjct: 627 TTSETAVTPTPVTPSSLSTDIPTTS 651
Score = 35.8 bits (81), Expect = 0.14
Identities = 68/351 (19%), Positives = 138/351 (39%), Gaps = 26/351 (7%)
Query: 192 STLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEA 251
ST T ST LP + L + ++ + +N + +E S +T S+SSS +
Sbjct: 354 STSMTGTLSTETSLPPTSSS-LPTTETATTPMTNLVTTTTEISSHSTP---SFSSSTIYS 409
Query: 252 PIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNS 311
+ S+S +S E+ + R T + +S S F+ + + S S
Sbjct: 410 TVTSHSTPRFTSSITTTETPSHSTPRFTSSFTNTKTTSHRSPSFTSLITTTETTSHSTPS 469
Query: 312 ENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSE 371
S ++ T+ +RS S + + S ++ +++HS+ S +
Sbjct: 470 FTSSITTTETTSHSARSFTSSITTTETTSHNTRSFTSSIT------TTETNSHSTTSFTS 523
Query: 372 NFNQESEGRNTGPWLSSSLRNRCTPLFS------------RRRREGRDESSRIPTSDTSS 419
+ ++ P SSS+ TPL S +S I T++T+S
Sbjct: 524 SITTTETTSHSTPSFSSSITTTETPLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTS 583
Query: 420 RSHIFRRESNEVVHLEAQNDP-LGAAANRPQASAASSSATTGGSTSDSA---QGGRNTGI 475
S S +++ P L ++ S ++++ T+ +TS++A + +
Sbjct: 584 HSTPGFTSSITTTETTSESTPSLSSSTIYSTVSTSTTAITSHFTTSETAVTPTPVTPSSL 643
Query: 476 SGILPGSLFRFAVPPALGSNLTDNVMITVDIIPSGWNSADGKSDKTKSAPS 526
S +P + R P ++G++ + IP+ ++ ++ S+PS
Sbjct: 644 STDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPS 694
>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
sapiens]
Length = 402
Score = 47.4 bits (111), Expect = 5e-05
Identities = 23/57 (40%), Positives = 32/57 (56%), Gaps = 10/57 (17%)
Query: 551 LCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELC 607
+C+IC A L+ PC+C GS++Y HQ C+ KW+ + GS TCELC
Sbjct: 169 ICKICFQGAEQGE--LLNPCRCDGSVRYTHQLCLLKWISER---GS-----WTCELC 215
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 45.4 bits (106), Expect = 2e-04
Identities = 96/353 (27%), Positives = 129/353 (36%), Gaps = 57/353 (16%)
Query: 108 GNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDF 167
G T + SWR+ + P S +R LERR S S S +
Sbjct: 1552 GPSERTRHNPSWRNHRSPSERS------------QRSSLERRHHSP-SQRSHCSPSRKNH 1598
Query: 168 TTSSYVQDRVPSYSQGARPKENSMSTLQL----NTSSTNHQLPSEHQTILSSRDSRNSL- 222
++ S R PS P E S +L + S +H+ PS+ + S S S
Sbjct: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPS 1658
Query: 223 -RSNFSSRE----SESSRSNTQPG----FSYSSSRDEAPIISNSERVVSSQR---PFQES 270
RS+ SS E S S RS+ P S S R +P S R S +R P + S
Sbjct: 1659 ERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPS-QRSHRGPSERRHHSPSKRS 1717
Query: 271 SDNEGRRTTRRLLSRIASSMSSTFF----SRRSSQDSLNTRSLNSENSYVSP---RILTA 323
+ RR+ R R S S RR S + SE S+ SP R +
Sbjct: 1718 HRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSP 1777
Query: 324 SQSRSNVPSA------SEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDS------- 370
S+ R + PS SE + SE + R R L SH SE S
Sbjct: 1778 SERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERS 1837
Query: 371 -ENFNQESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSH 422
++ S + LS R+RC+P R G S + S S RSH
Sbjct: 1838 HRRISERSHSPSEKSHLSPLERSRCSP----SERRGHSSSGKTCHS-PSERSH 1885
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 45.1 bits (105), Expect = 2e-04
Identities = 68/330 (20%), Positives = 127/330 (38%), Gaps = 36/330 (10%)
Query: 215 SRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNS------ERVVSSQRPFQ 268
+R S +S S+ E + +PG S AP S ++ V Q+P +
Sbjct: 261 TRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVE 320
Query: 269 ESSDN----------EGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSP 318
S D+ E + T+ ++S+ + + SS DS ++ S + + P
Sbjct: 321 SSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP 380
Query: 319 RILTASQSRSNVPSASEVPDNRASEASQ----GFRFLRRRWGLSSLSHNHSSESDSENFN 374
T + S + A+ Q G + L R+ + + SSE +S +
Sbjct: 381 AGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRK------ADSSSSEEESSSSE 434
Query: 375 QESEGRNTGPWLSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFRRESNEVVHL 434
+E + + L +++ +G +SS SD+SS + S V
Sbjct: 435 EEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS--DSDSSSSEEEEEKTSKSAVKK 492
Query: 435 EAQNDPLGAAANRPQASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALGS 494
+ Q GAA ++P ++ + ++ S+SD + + G GS R P A G+
Sbjct: 493 KPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKG--KGSP-RPQAPKANGT 549
Query: 495 NLTDNVMITVDIIPSGWNSADGKSDKTKSA 524
+ +T + NS + + +K K+A
Sbjct: 550 S-----ALTAQNGKAAKNSEEEEEEKKKAA 574
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 45.1 bits (105), Expect = 2e-04
Identities = 78/284 (27%), Positives = 118/284 (41%), Gaps = 39/284 (13%)
Query: 16 PSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAWYSESEITQG 75
P SS R +G++ SS ++ S+ SS DS+ S+ SP Q + E E +
Sbjct: 791 PPSSCQRR--AGTKRSS-RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGS 847
Query: 76 ARSRSQNQQ-RDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGS 134
SRS+++ R H S R S+ R+ + SD+S S R S S
Sbjct: 848 EHSRSRSRSGRRHSSHR----------SSRRSYSSS----SDASSDQSCYSRQRSYSDDS 893
Query: 135 FGTDLMRERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTL 194
+ R RR +R DS S+ HRS SS D S+S
Sbjct: 894 YSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD-------------YSLSCS 940
Query: 195 QLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNT-QPGFSYSSSRDEAPI 253
Q + S +H + ++ R +S + S R S S+ +++ Q SYS R +
Sbjct: 941 QSRSRSRSH---TRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRS-T 996
Query: 254 ISNSERVVSSQRPFQESSDNEGRRTTRR--LLSRIASSMSSTFF 295
S S+R S +R + S E R + RR + S+I S S +F
Sbjct: 997 RSPSQRSGSRKRSWGHESPEE-RHSGRRDFIRSKIYRSQSPHYF 1039
Score = 36.2 bits (82), Expect = 0.11
Identities = 55/256 (21%), Positives = 94/256 (36%), Gaps = 36/256 (14%)
Query: 11 RISVQPSSSLSARMMSGSRGSSLNDTY----------HSRDSSFRLDSEYQSTSASASAS 60
R S SS S+ SR S +D HS+ S DS+Y S+ +
Sbjct: 867 RRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRH 926
Query: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWR 120
+ S+ S +RSRS++ R+ R + ++C+ S + + + SW+
Sbjct: 927 KYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSSSCSRSRSKRRS---RSTTAHSWQ 983
Query: 121 HSQVPRSSSMVLGSFGTDLMRERRDLERRTDS---SISNLMDYSHRSG--DFTTSSYVQD 175
S+ S+ D R R +R+ S S + SG DF S +
Sbjct: 984 RSR----------SYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRS 1033
Query: 176 RVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDS--------RNSLRSNFS 227
+ P Y + R + S PS++ I + R S +NS+ +
Sbjct: 1034 QSPHYFRSGRGEGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKNSVTAKLL 1093
Query: 228 SRESESSRSNTQPGFS 243
+ +S + +P S
Sbjct: 1094 LEKIQSRKVERKPSVS 1109
Score = 30.8 bits (68), Expect = 4.5
Identities = 66/259 (25%), Positives = 103/259 (39%), Gaps = 37/259 (14%)
Query: 26 SGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASASPFQSAW-----YSESEITQGARSRS 80
SGS S R SS R S +S S+S+ AS QS + YS+ + +
Sbjct: 845 SGSEHSRSRSRSGRRHSSHR--SSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSR 902
Query: 81 QNQQRDHDSKRPKLSCTNCTTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLM 140
++ +R HDS ++ +S R+ + ++ D RS S
Sbjct: 903 RHSKRSHDS-----DDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRS-------RSHT 950
Query: 141 RERRDLERRTDSSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSS 200
RER R+ SS + RS T S+ + R SYS ++ S ST + S
Sbjct: 951 RERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSR--SYS-----RDRSRSTRSPSQRS 1003
Query: 201 TNHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERV 260
+ + H+ S + R+S R +F + S+S P + + S R E P + R
Sbjct: 1004 GSRKRSWGHE----SPEERHSGRRDFIRSKIYRSQS---PHY-FRSGRGEGPGKKDDGRG 1055
Query: 261 VSSQR---PFQESSDNEGR 276
S+ P Q S+ GR
Sbjct: 1056 DDSKATGPPSQNSNIGTGR 1074
>gi|57977325 membrane-associated ring finger (C3HC4) 4 [Homo
sapiens]
Length = 410
Score = 43.5 bits (101), Expect = 7e-04
Identities = 22/60 (36%), Positives = 29/60 (48%), Gaps = 10/60 (16%)
Query: 551 LCRICQMAAASSSNLLIEPCKCTGSLQYVHQDCMKKWLQAKINSGSSLEAVTTCELCKEK 610
LCRIC L+ PC+C GS++ HQ C+ KW+ S +CELC K
Sbjct: 162 LCRICFQGPEQGE--LLSPCRCDGSVKCTHQPCLIKWI--------SERGCWSCELCYYK 211
>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
sapiens]
Length = 1804
Score = 43.1 bits (100), Expect = 9e-04
Identities = 55/218 (25%), Positives = 88/218 (40%), Gaps = 37/218 (16%)
Query: 47 DSEYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDH---DSKRPKLSCTNCTTSA 103
DS Y S S+S + S S+ +S+ + G R+ S+ ++ S + T+ S
Sbjct: 1278 DSHYSSHSSSNTLSSNASSAHSDEKWYDGDRTESELNSYNYLQGTSADSGIDTTSYGPSH 1337
Query: 104 GRNVGNGLNTLSDSSW----RHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMD 159
G G T S S + + + SSS V+ L E L+R+T+SS+S +D
Sbjct: 1338 GSTASLGAATSSPRSGPGKEKVAPLWHSSSEVISMADRTLETESHGLDRKTESSLS--LD 1395
Query: 160 YSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSR 219
+S G+ P ST +N +++ H + +SSR S
Sbjct: 1396 IHSKS----------------QAGSTPLTRENSTFSINDAAS-------HTSTMSSRHSA 1432
Query: 220 N-----SLRSNFSSRESESSRSNTQPGFSYSSSRDEAP 252
+ S RS+ ++ S P FS SSS P
Sbjct: 1433 SPVVFTSARSSPKEELHPAAPSQLAPSFSSSSSSSSGP 1470
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 42.7 bits (99), Expect = 0.001
Identities = 92/421 (21%), Positives = 150/421 (35%), Gaps = 41/421 (9%)
Query: 49 EYQSTSASASASPFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCTNCTTSAGRNVG 108
E Q TSASAS SP +A + + + + Q Q + S + TTSAG
Sbjct: 752 EGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSR------TTSAG---- 801
Query: 109 NGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDYSHRSGDFT 168
SS P S + S T + T S + L+ S G
Sbjct: 802 ---TATPSSSGASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSASASHGAIP 858
Query: 169 TSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQTILSSRDSRNSLRSNFSS 228
S+ + + + E S + SS S +T SR ++ + +S
Sbjct: 859 VSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQT--QRTRTS 916
Query: 229 RESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTRRLLSRIAS 288
R S++ +Q ++S+ P I+++ S G+ T L+S A+
Sbjct: 917 RGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISN-AT 975
Query: 289 SMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILTASQSRSNVPSASEVPDNRASEASQGF 348
+ T+ S S+ + +P +T + S S A+ +P S S G
Sbjct: 976 PLPVTYASSAST-------------GHTTPLHVTDASSVS-TGHATPLPVTSPSSVSTGH 1021
Query: 349 RFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTG---PWLSSSLRNRCTPL-FSRRRRE 404
SS S H + +F+ S G +T SS+ TPL +
Sbjct: 1022 TTPLPVTDTSSESTGHVTPLPVTSFSSASTGDSTPLPVTDTSSASTGHVTPLPVTSLSSA 1081
Query: 405 GRDESSRIPTSDTSSRSHIFRRESNEVVHLE-AQNDPLGAAANRPQASAASSSATTGGST 463
+++ +P +DTSS S + L + P +SSA+TG +T
Sbjct: 1082 STGDTTPLPVTDTSSAS------TGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHAT 1135
Query: 464 S 464
S
Sbjct: 1136 S 1136
Score = 29.6 bits (65), Expect = 10.0
Identities = 52/226 (23%), Positives = 85/226 (37%), Gaps = 37/226 (16%)
Query: 100 TTSAGRNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMD 159
TTS +GN T + + + V + S+ G G + RT S +++ D
Sbjct: 141 TTSTDSTLGNTEETSTAGTESSTPVTSAVSITAGQEG----------QSRTTSWRTSIQD 190
Query: 160 YSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEH--------QT 211
S S + T S R E+ STL T+ST PS H +T
Sbjct: 191 TSASSQNHWTRSTQTTR-----------ESQTSTLTHRTTSTPSFSPSVHNVTGTVSQKT 239
Query: 212 ILSSRDSRNSLRS--NFSSRESESSRSNTQPGFSYSSSRDEAPI-ISNSERVVSSQRPFQ 268
S + +SL S N S SE T G + + + + + ++ S V+S
Sbjct: 240 SPSGETATSSLCSVTNTSMMTSEKITVTTSTGSTLGNPGETSSVPVTGSLMPVTSAALVT 299
Query: 269 ESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENS 314
+ + T R S+ +T FS+ S+ T ++ N+
Sbjct: 300 FDPEGQSPATFSR-----TSTQDTTAFSKNHQTQSVETTRVSQINT 340
>gi|239758038 PREDICTED: mucin 3A, cell surface associated, partial
[Homo sapiens]
Length = 909
Score = 42.4 bits (98), Expect = 0.001
Identities = 63/276 (22%), Positives = 107/276 (38%), Gaps = 34/276 (12%)
Query: 168 TTSSYVQDRVPSYSQGARPKENSMSTLQLNTSS------TNHQLPSEHQTILSSRDSRNS 221
TTS R PS++ E S+ TSS T+H PS +I ++ + +S
Sbjct: 2 TTSETPSHRTPSFTSSITTTETPSSSTPSFTSSITTTETTSHSTPSFTSSISTTETTSHS 61
Query: 222 LRSNFSSRESESSRSNTQPGFSYSSSRDEAPIISN---SERVVSSQRPFQESSDNEGRRT 278
S S + S++ P ++ S + E P S + + +++ P + T
Sbjct: 62 TPSFTSLITITETTSHSTPSYTTSITTTETPSHSTPSYTTSITTTETPSHSTPSFTSSIT 121
Query: 279 TRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSEN-----------SYVSPRILTASQSR 327
T S S +S+ R + S +T S S N SY++ I T
Sbjct: 122 TTETTSHSTPSFTSSI--RTTETTSYSTPSFTSSNTITETTSHSTPSYIT-SITTTETPS 178
Query: 328 SNVP--SASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRNTGPW 385
S+ P S+S S ++ GF ++ + +HS+ S + + + P
Sbjct: 179 SSTPSFSSSITTTETTSHSTPGFTSSI----TTTETTSHSTPSFTSSITTTETTSHDTPS 234
Query: 386 LSSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRS 421
+SS+ TP S +S I T+ T+S S
Sbjct: 235 FTSSITTSETPSHST-----PSSTSLITTTKTTSHS 265
Score = 40.4 bits (93), Expect = 0.006
Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 21/204 (10%)
Query: 152 SSISNLMDYSHRSGDFTTSSYVQDRV----PSYSQGARPKEN------SMSTLQLNTSST 201
SSI S+ + FT+S+ + + PSY E S S+ T +T
Sbjct: 135 SSIRTTETTSYSTPSFTSSNTITETTSHSTPSYITSITTTETPSSSTPSFSSSITTTETT 194
Query: 202 NHQLPSEHQTILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEAPIIS--NSER 259
+H P +I ++ + +S S SS + + S+ P F+ S + E P S +S
Sbjct: 195 SHSTPGFTSSITTTETTSHSTPSFTSSITTTETTSHDTPSFTSSITTSETPSHSTPSSTS 254
Query: 260 VVSSQRPFQESSDN-EGRRTTRRLLSRIASSMSS-------TFFSRRSSQDSLNTRSLNS 311
++++ + S+ + TT S A S +S T + RS S+ T NS
Sbjct: 255 LITTTKTTSHSTPSFTSSITTTETTSHSAHSFTSSITTTETTSHNTRSFTSSITTTETNS 314
Query: 312 ENSYVSPRILTASQSRS-NVPSAS 334
++ +T +++ S + PS S
Sbjct: 315 HSTTSFTSSITTTETTSHSTPSFS 338
Score = 29.6 bits (65), Expect = 10.0
Identities = 49/203 (24%), Positives = 83/203 (40%), Gaps = 22/203 (10%)
Query: 152 SSISNLMDYSHRSGDFTTSSYVQDRVPSYSQGARPKENSMSTLQLNTSSTNHQLPSEHQT 211
S I+ SH + FT+S + S A +S++T T +T+H S +
Sbjct: 254 SLITTTKTTSHSTPSFTSSITTTETT---SHSAHSFTSSITT----TETTSHNTRSFTSS 306
Query: 212 ILSSRDSRNSLRSNFSSRESESSRSNTQPGFSYSSSRDEA---PIISNSERVVSSQRPFQ 268
I ++ + +S S SS + + S++ P FS S + E SE V+
Sbjct: 307 ITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITTTETXXXXXXXTSETAVTPTPVTP 366
Query: 269 ESSDNEGRRTTRRLL--SRIASSMSST----FFSRRSSQDSLNTR------SLNSENSYV 316
S + T+ R L S + +S S T F S + +L TR S + +++
Sbjct: 367 SSLSTDIPTTSLRTLTPSSVGTSTSLTTTTDFPSIPTDISTLPTRTHIISSSPSIQSTET 426
Query: 317 SPRILTASQSRSNVPSASEVPDN 339
S + T S + S V + +N
Sbjct: 427 SSLVGTTSPTMSTVRMTLRITEN 449
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 41.6 bits (96), Expect = 0.003
Identities = 116/582 (19%), Positives = 218/582 (37%), Gaps = 77/582 (13%)
Query: 1 MESKPSRIPRRISVQPSSSLSARMMSGSRGSSLNDTYHSRDSSFRLDSEYQSTSASASAS 60
++S+ S + R+ S Q S A SGSR D+ SR + L QS + S S
Sbjct: 2278 VKSELSPVARQTS-QIGGSSKAPSRSGSR-----DSTPSRPAQQPLSRPIQSPGRN-SIS 2330
Query: 61 PFQSAWYSESEITQGARSRSQNQQRDHDSKRPKLSCT---------NCTTSAG------- 104
P ++ ++++Q R+ S + S K+S T N T G
Sbjct: 2331 PGRNGISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASS 2390
Query: 105 ----RNVGNGLNTLSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLERRTDSSISNLMDY 160
+ GLN +++ + + +V S S G++ R R + R + I
Sbjct: 2391 IPRSESASKGLNQMNNGNGANKKVELSRMSSTKSSGSESDRSERPVLVRQSTFIKEAPSP 2450
Query: 161 SHR-----SGDFTT-SSYVQDRVPSYSQGARPKEN-SMSTLQLNTSSTNH-----QLPSE 208
+ R S F + S + P+ SQ P + S+ + L+T S+ +LP
Sbjct: 2451 TLRRKLEESASFESLSPSSRPASPTRSQAQTPVLSPSLPDMSLSTHSSVQAGGWRKLPPN 2510
Query: 209 HQTILSSRDSRNSLRSNFSSRESES------SRSNTQPGFSYSSSRDEAPIISNSERVVS 262
+ D R + R + + SES +RS T +S P +S R S
Sbjct: 2511 LSPTIEYNDGRPAKRHDIARSHSESPSRLPINRSGTWKR-EHSKHSSSLPRVSTWRRTGS 2569
Query: 263 SQRPFQESSDNEGRRTTRRLLSRIASSMSSTFFSRRSSQDSLNTRSLNSENSYVSPRILT 322
S SS++ + + + +S+S T S+ + + T EN +
Sbjct: 2570 SSSILSASSESSEKAKSED--EKHVNSISGTKQSKENQVSAKGTWRKIKENEF------- 2620
Query: 323 ASQSRSNVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRN- 381
S S S+ + A+ ++ + + S + + + N GR+
Sbjct: 2621 -----SPTNSTSQTVSSGATNGAESKTLIYQMAPAVSKTEDVWVRIEDCPINNPRSGRSP 2675
Query: 382 TG--PWLSSSLRNRCTPLFSRRRREGRDESSR--IPTSDTSSRSHIFRRESNEVVHLEAQ 437
TG P + S+ + P ++ +D ++ + R+ N + ++A
Sbjct: 2676 TGNTPPVIDSVSEKANPNI----KDSKDNQAKQNVGNGSVPMRTVGLENRLNSFIQVDAP 2731
Query: 438 NDP---LGAAANRP-QASAASSSATTGGSTSDSAQGGRNTGISGILPGSLFRFAVPPALG 493
+ + N P S + S+ + S+ +++ SG + + F P+
Sbjct: 2732 DQKGTEIKPGQNNPVPVSETNESSIVERTPFSSSSSSKHSSPSGTVAARVTPFNYNPSPR 2791
Query: 494 SNLTDNVMITVDIIPSGWNS----ADGKSDKTKSAPSRDPER 531
+ D+ IP+ N+ D K+D T+S+ ++ P+R
Sbjct: 2792 KSSADSTSARPSQIPTPVNNNTKKRDSKTDSTESSGTQSPKR 2833
Score = 35.4 bits (80), Expect = 0.18
Identities = 76/392 (19%), Positives = 139/392 (35%), Gaps = 51/392 (13%)
Query: 114 LSDSSWRHSQVPRSSSMVLGSFGTDLMRERRDLER-------RTDSSISNLMDYSHRSGD 166
L + +HS PR+ +LG DL + +D++R DS + +
Sbjct: 2056 LKGDNEKHS--PRNMGGILGE---DLTLDLKDIQRPDSEHGLSPDSENFDWKAIQEGANS 2110
Query: 167 FTTSSYVQDRVPSYSQGARPKENSMSTLQ--LNTSSTNHQLPSEHQTILSSRDSRNSLR- 223
+S + S+ A +S+ +L+ ++ S H P + + +S L+
Sbjct: 2111 IVSSLHQAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPFTSNKGPRILKP 2170
Query: 224 ---SNFSSRESESSRSNTQPGFSYSSSRDEAPIISNSERVVSSQRPFQESSDNEGRRTTR 280
S +++ ES + G S + SNSE ++P Q + + R T
Sbjct: 2171 GEKSTLETKKIESESKGIKGGKKVYKSLITGKVRSNSEISGQMKQPLQANMPSISRGRTM 2230
Query: 281 RLLSRIASSMSSTF------------FSRRSSQDSLNTRSLNSENSYVSPRILTASQSRS 328
+ + +S SST S+ S+ T S V + ++ S
Sbjct: 2231 IHIPGVRNSSSSTSPVSKKGPPLKTPASKSPSEGQTATTSPRGAKPSVKSELSPVARQTS 2290
Query: 329 NVPSASEVPDNRASEASQGFRFLRRRWGLSSLSHNHSSESDSENFNQESEGRN--TGPWL 386
+ +S+ P S S R S S N S GRN + P
Sbjct: 2291 QIGGSSKAPSRSGSRDSTPSR---------PAQQPLSRPIQSPGRNSISPGRNGISPPNK 2341
Query: 387 SSSLRNRCTPLFSRRRREGRDESSRIPTSDTSSRSHIFR-----RESNEVVHLEAQNDPL 441
S L +P + + G + S S+ ++ + + ++ + E+ + L
Sbjct: 2342 LSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQTGLSKNASSIPRSESASKGL 2401
Query: 442 -----GAAANRPQASAASSSATTGGSTSDSAQ 468
G AN+ + SS + GS SD ++
Sbjct: 2402 NQMNNGNGANKKVELSRMSSTKSSGSESDRSE 2433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.122 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,466,926
Number of Sequences: 37866
Number of extensions: 1129698
Number of successful extensions: 6297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 210
Number of HSP's that attempted gapping in prelim test: 5508
Number of HSP's gapped (non-prelim): 785
length of query: 704
length of database: 18,247,518
effective HSP length: 109
effective length of query: 595
effective length of database: 14,120,124
effective search space: 8401473780
effective search space used: 8401473780
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.