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Search of human proteins with 122937502
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937502 transmembrane channel-like 3 [Homo sapiens]
(1100 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937502 transmembrane channel-like 3 [Homo sapiens] 2215 0.0
gi|94536852 transmembrane cochlear-expressed protein 2 [Homo sap... 639 0.0
gi|21071070 transmembrane channel-like 1 [Homo sapiens] 576 e-164
gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens] 146 9e-35
gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens] 146 9e-35
gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens] 122 2e-27
gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens] 122 2e-27
gi|23943900 transmembrane channel-like 8 [Homo sapiens] 108 2e-23
gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens] 103 7e-22
gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens] 103 7e-22
gi|187608784 transmembrane channel-like 6 [Homo sapiens] 97 8e-20
gi|187608791 transmembrane channel-like 6 [Homo sapiens] 97 8e-20
gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens] 82 2e-15
gi|32484977 angiomotin like 2 [Homo sapiens] 44 0.001
gi|8923243 palmdelphin [Homo sapiens] 39 0.021
gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens] 39 0.035
gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens] 39 0.035
gi|54792782 C-type lectin domain family 16, member A [Homo sapiens] 38 0.046
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 38 0.046
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.060
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 36 0.23
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 35 0.39
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 34 0.87
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 34 0.87
gi|113430845 PREDICTED: similar to protein kinase, DNA-activated... 34 0.87
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 34 0.87
gi|199562283 retrotransposon-like 1 [Homo sapiens] 33 1.1
gi|54112407 protein kinase CHK2 isoform c [Homo sapiens] 33 1.5
gi|22209009 protein kinase CHK2 isoform b [Homo sapiens] 33 1.5
gi|6005850 protein kinase CHK2 isoform a [Homo sapiens] 33 1.5
>gi|122937502 transmembrane channel-like 3 [Homo sapiens]
Length = 1100
Score = 2215 bits (5739), Expect = 0.0
Identities = 1100/1100 (100%), Positives = 1100/1100 (100%)
Query: 1 MKTSKASQRYRGIRRNASQCYLYQESLLLSNLDDSFSADETGDSNDPEQIFQNIQFQKDL 60
MKTSKASQRYRGIRRNASQCYLYQESLLLSNLDDSFSADETGDSNDPEQIFQNIQFQKDL
Sbjct: 1 MKTSKASQRYRGIRRNASQCYLYQESLLLSNLDDSFSADETGDSNDPEQIFQNIQFQKDL 60
Query: 61 MANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIF 120
MANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIF
Sbjct: 61 MANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIF 120
Query: 121 IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK 180
IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK
Sbjct: 121 IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK 180
Query: 181 TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVGMAVFAY 240
TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVGMAVFAY
Sbjct: 181 TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVGMAVFAY 240
Query: 241 SFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREAI 300
SFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREAI
Sbjct: 241 SFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREAI 300
Query: 301 LEEQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKN 360
LEEQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKN
Sbjct: 301 LEEQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKN 360
Query: 361 EVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNS 420
EVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNS
Sbjct: 361 EVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNS 420
Query: 421 MSIEEMATKNNTSHWIDSTTFFATRTAPEEEKWSTSRPGMGLRRNNTWALEETSISAYTM 480
MSIEEMATKNNTSHWIDSTTFFATRTAPEEEKWSTSRPGMGLRRNNTWALEETSISAYTM
Sbjct: 421 MSIEEMATKNNTSHWIDSTTFFATRTAPEEEKWSTSRPGMGLRRNNTWALEETSISAYTM 480
Query: 481 PLIKANKTSLHTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDY 540
PLIKANKTSLHTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDY
Sbjct: 481 PLIKANKTSLHTQSPQDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDY 540
Query: 541 WCWDLESKFPEYGEFKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAV 600
WCWDLESKFPEYGEFKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAV
Sbjct: 541 WCWDLESKFPEYGEFKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAV 600
Query: 601 LTCNVPHQQVFRASRSNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDI 660
LTCNVPHQQVFRASRSNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDI
Sbjct: 601 LTCNVPHQQVFRASRSNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDI 660
Query: 661 VSETIEKDFPVWFGSVVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQN 720
VSETIEKDFPVWFGSVVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQN
Sbjct: 661 VSETIEKDFPVWFGSVVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQN 720
Query: 721 ARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSK 780
ARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSK
Sbjct: 721 ARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSK 780
Query: 781 SGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYLHGLCASTSDLHRNRSRTP 840
SGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYLHGLCASTSDLHRNRSRTP
Sbjct: 781 SGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYLHGLCASTSDLHRNRSRTP 840
Query: 841 MTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINECDSYKKKH 900
MTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINECDSYKKKH
Sbjct: 841 MTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINECDSYKKKH 900
Query: 901 LNVWPERHFKIDASGDIVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPP 960
LNVWPERHFKIDASGDIVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPP
Sbjct: 901 LNVWPERHFKIDASGDIVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPP 960
Query: 961 RSLIDLRRAPHFYIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAYVPRKPRSRNFQ 1020
RSLIDLRRAPHFYIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAYVPRKPRSRNFQ
Sbjct: 961 RSLIDLRRAPHFYIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAYVPRKPRSRNFQ 1020
Query: 1021 YPQPPLKPRGKPRFEPSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRR 1080
YPQPPLKPRGKPRFEPSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRR
Sbjct: 1021 YPQPPLKPRGKPRFEPSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRR 1080
Query: 1081 KAKSGQELTVDLDDLICSDV 1100
KAKSGQELTVDLDDLICSDV
Sbjct: 1081 KAKSGQELTVDLDDLICSDV 1100
>gi|94536852 transmembrane cochlear-expressed protein 2 [Homo
sapiens]
Length = 906
Score = 639 bits (1647), Expect = 0.0
Identities = 334/789 (42%), Positives = 488/789 (61%), Gaps = 48/789 (6%)
Query: 30 SNLDDSFSADETGDSNDPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFE 89
S+L S S E+ + QI + ++ +K L+A +R +PW M +KL LR+A+ V K+E
Sbjct: 136 SSLASSASGGESLSEEELAQILEQVEEKKKLIATMRSKPWPMAKKLTELREAQEFVEKYE 195
Query: 90 GRLTRTRG-----YQAAGAELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIF 144
G L + +G Y+ A+ W KF R NF IPWEM+IK IESHFGS VASYFIF
Sbjct: 196 GALGKGKGKQLYAYKMLMAKKWVKFKRDFDNFKTQCIPWEMKIKDIESHFGSSVASYFIF 255
Query: 145 LRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQ 204
LRW++G+N+VL + ++IPE++ G P+GS RKT+P+ + A D +W GY++
Sbjct: 256 LRWMYGVNLVLFGLIFGLVIIPEVLMGMPYGSIPRKTVPRAEEEKAMDFSVLWDFEGYIK 315
Query: 205 YSVLFYGYYGRERKIGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNEN 264
YS LFYGYY +R IG YRLP+AYF+VG++VF YS II+++ MA N++ S ++N
Sbjct: 316 YSALFYGYYNNQRTIGWLRYRLPMAYFMVGVSVFGYSLIIVIRSMASNTQGSTGEGESDN 375
Query: 265 YTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANI 324
+TF +++F +WDYLIGN E A++K A+I S +E+I++EQE K +N+ +T LR++AN
Sbjct: 376 FTFSFKMFTSWDYLIGNSETADNKYASITTSFKESIVDEQESNKEENIHLTRFLRVLANF 435
Query: 325 LVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALE 384
L++ L GS YLIYFVV RSQ+ + + ++ +E+NEV +V+SL+ M P F+ IAALE
Sbjct: 436 LIICCLCGSGYLIYFVVKRSQQFSK-MQNVSWYERNEVEIVMSLLGMFCPPLFETIAALE 494
Query: 385 MYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFAT 444
YHPRT L++QL R+ L+LGNLY+ ++AL+D V+ E KN T HW T F
Sbjct: 495 NYHPRTGLKWQLGRIFALFLGNLYTFLLALMDDVHLKLANEETIKNIT-HW----TLF-- 547
Query: 445 RTAPEEEKWSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLH-TQSPQDQCWETY 503
W+ S P + LH P+ CWET
Sbjct: 548 -NYYNSSGWNESVP----------------------------RPPLHPADVPRGSCWETA 578
Query: 504 VGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLH 563
VG E ++L++ DML T +ILL DF R FVR+++ WCWDLE+ FP Y EF I+ NVL
Sbjct: 579 VGIEFMRLTVSDMLVTYITILLGDFLRACFVRFMNYCWCWDLEAGFPSYAEFDISGNVLG 638
Query: 564 LVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAM 623
L++NQGMIWMG+F++P L NVL+L+ MY + WAV++ NVPH++VF+ASRSNNFY+ +
Sbjct: 639 LIFNQGMIWMGSFYAPGLVGINVLRLLTSMYFQCWAVMSSNVPHERVFKASRSNNFYMGL 698
Query: 624 LLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSP 683
LL +LFL +LP + I+ PS +CGPFSG+ ++YD++ ETIE DFP + G + +++P
Sbjct: 699 LLLVLFLSLLPVAYTIMSLPPSFDCGPFSGKNRMYDVLQETIENDFPTFLGKIFAFLANP 758
Query: 684 VVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQEE- 742
+I+PA+LL+F+ IYYL S+++SL +N QL+ +IQ R +K + +A + E+
Sbjct: 759 GLIIPAILLMFLAIYYLNSVSKSLSRANAQLRKKIQVLREVEKSHKSVKGKATARDSEDT 818
Query: 743 --STKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQS--MPQSPRPG 798
S+ K LT + ++ S + + G+S S T+ S +P S PG
Sbjct: 819 PKSSSKNATQLQLTKEETTPPSASQSQAMDKKAQGPGTSNSASRTTLPASGHLPISRPPG 878
Query: 799 DRAPSSPLP 807
S P
Sbjct: 879 IGPDSGHAP 887
>gi|21071070 transmembrane channel-like 1 [Homo sapiens]
Length = 760
Score = 576 bits (1485), Expect = e-164
Identities = 289/704 (41%), Positives = 432/704 (61%), Gaps = 38/704 (5%)
Query: 39 DETGDSNDPEQIFQNIQFQKDLMANIRCRPWTMGQKLRALRQAKNIVLKFEGRLTRTRG- 97
+E D + E++ + ++ ++A ++C+PW M +K+ L++AK V + EG L + +G
Sbjct: 81 EEEIDEEELERLKAELDEKRQIIATVKCKPWKMEKKIEVLKEAKKFVSENEGALGKGKGK 140
Query: 98 ----YQAAGAELWRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINI 153
++ A+ W KF R NF +PWE +IK IES FGS VASYF+FLRW++G+N+
Sbjct: 141 RWFAFKMMMAKKWAKFLRDFENFKAACVPWENKIKAIESQFGSSVASYFLFLRWMYGVNM 200
Query: 154 VLTIMTGAFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYY 213
VL I+T + I++PE + G P+GS RKT+P+ + +SA + ++ G QYSVLFYGYY
Sbjct: 201 VLFILTFSLIMLPEYLWGLPYGSLPRKTVPRAEEASAANFGVLYDFNGLAQYSVLFYGYY 260
Query: 214 GRERKIGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFC 273
+R IG +RLPL+YFLVG+ YSF+++LK M KN + + F W+VF
Sbjct: 261 DNKRTIGWMNFRLPLSYFLVGIMCIGYSFLVVLKAMTKNIGDD-GGGDDNTFNFSWKVFT 319
Query: 274 AWDYLIGNPEAAESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLLSLAGS 333
+WDYLIGNPE A++K +I + +EAI EE+ + +N+ + LR +AN V L+L GS
Sbjct: 320 SWDYLIGNPETADNKFNSITMNFKEAITEEKAAQVEENVHLIRFLRFLANFFVFLTLGGS 379
Query: 334 IYLIYFVVDRSQKL-EQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTL 392
YLI++ V RSQ+ +Q L WEKNE+++V+SL+ M P+ FDL A LE YHP L
Sbjct: 380 GYLIFWAVKRSQEFAQQDPDTLGWWEKNEMNMVMSLLGMFCPTLFDLFAELEDYHPLIAL 439
Query: 393 RFQLARVLVLYLGNLYSLIIALLDKVNSMSIEEMATKNNTSHWIDSTTFFATRTAPEEEK 452
++ L R+ L LGNLY I+AL+D++N+ EE K N + W
Sbjct: 440 KWLLGRIFALLLGNLYVFILALMDEINNKIEEEKLVKANITLW----------------- 482
Query: 453 WSTSRPGMGLRRNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEMLKLS 512
M N +++ T + P P+ CWET VGQE ++L+
Sbjct: 483 ----EANMIKAYNASFSENSTGPPFFVHP----------ADVPRGPCWETMVGQEFVRLT 528
Query: 513 IIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIAENVLHLVYNQGMIW 572
+ D+L T +IL+ DF R FVR+ + WCWDLE +P Y EF I+ NVL L++NQGMIW
Sbjct: 529 VSDVLTTYVTILIGDFLRACFVRFCNYCWCWDLEYGYPSYTEFDISGNVLALIFNQGMIW 588
Query: 573 MGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNNFYLAMLLFMLFLCM 632
MG+FF+P LP N+L+L MY + WAV+ CNVP +VF+ASRSNNFYL MLL +LFL
Sbjct: 589 MGSFFAPSLPGINILRLHTSMYFQCWAVMCCNVPEARVFKASRSNNFYLGMLLLILFLST 648
Query: 633 LPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAVLL 692
+P ++ IV PS +CGPFSG+ ++++++ ET+E DFP W ++ +S+P +++ +L+
Sbjct: 649 MPVLYMIVSLPPSFDCGPFSGKNRMFEVIGETLEHDFPSWMAKILRQLSNPGLVIAVILV 708
Query: 693 LFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEAR 736
+ + IYYL + A+ K +N LK +++ E+K + +M AR
Sbjct: 709 MVLAIYYLNATAKGQKAANLDLKKKMKMQALENKMRNKKMAAAR 752
>gi|238550100 transmembrane channel-like 7 isoform b [Homo sapiens]
Length = 613
Score = 146 bits (369), Expect = 9e-35
Identities = 85/231 (36%), Positives = 128/231 (55%), Gaps = 12/231 (5%)
Query: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSD---YWCWDLESKFPEYGEF 555
CWET VGQEM KL I D + +A L +DF R L V Y S CW + EF
Sbjct: 376 CWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EF 428
Query: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASR 615
I +NVL +VY Q + W+GAFFSP LPA LK I + Y++ W++L P + FRAS
Sbjct: 429 AIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASN 488
Query: 616 SNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGS 675
SN F+L +LL L L ++P +I R S CGPF+ ++++ +T+ FP S
Sbjct: 489 SNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQS 547
Query: 676 VVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDK 726
+ ++S +P +++ ++++Y ++A + K QL+ Q+ + S DK
Sbjct: 548 FIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQL-SLESRDK 597
Score = 125 bits (314), Expect = 2e-28
Identities = 92/343 (26%), Positives = 155/343 (45%), Gaps = 30/343 (8%)
Query: 106 WRKFARLACNFVVIFIPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVI 165
W++F A W I+ IE FG+G+ SYF FLR+L +N+V+ ++ +++
Sbjct: 18 WKRFLEKAREMTTHLELWREDIRSIEGKFGTGIQSYFSFLRFLVLLNLVIFLIIFMLVLL 77
Query: 166 PELIAGQPFGSTARKTIPKEQVSSAQDLDTVWSLG---------------GYLQYSVLFY 210
P L+ +++ IP + + + V S G G+L+ + LFY
Sbjct: 78 PVLLTKYKITNSSFVLIPFKDMDKQCTVYPVSSSGLIYFYSYIIDLLSGTGFLEETSLFY 137
Query: 211 GYYGRER-KIGRAGYRLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCW 269
G+Y + K Y LPLAY L +A A S + ++K+ + + +L + ++C
Sbjct: 138 GHYTIDGVKFQNFTYDLPLAYLLSTIASLALSLLWIVKRSVEGFKINLIRSEEHFQSYCN 197
Query: 270 RVFCAWDYLIGNPEAAESKTAAIVNSIREAILEEQEKKK-----SKNLAVTICLRIIANI 324
++F WD+ I N A+ K +++ +R + EE+ ++K S+ LR+ N
Sbjct: 198 KIFAGWDFCITNRSMADLKHSSLRYELRADLEEERMRQKIAERTSEETIRIYSLRLFLNC 257
Query: 325 LVLLSLAGSIYLIYFVVDRSQKLEQSKKELTLWEKNE-------VSVVVSLVTMIAPSAF 377
+VL L Y IY SQ E KKE+ E S+V++L I P F
Sbjct: 258 IVLAVLGACFYAIYVATVFSQ--EHMKKEIDKMVFGENLFILYLPSIVITLANFITPMIF 315
Query: 378 DLIAALEMYHPRTTLRFQLARVLVLYLGNLYSLIIALLDKVNS 420
I E Y P +R + R + + L + L+ L K+ S
Sbjct: 316 AKIIRYEDYSPGFEIRLTILRCVFMRLATICVLVFTLGSKITS 358
>gi|238550098 transmembrane channel-like 7 isoform a [Homo sapiens]
Length = 723
Score = 146 bits (369), Expect = 9e-35
Identities = 85/231 (36%), Positives = 128/231 (55%), Gaps = 12/231 (5%)
Query: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSD---YWCWDLESKFPEYGEF 555
CWET VGQEM KL I D + +A L +DF R L V Y S CW + EF
Sbjct: 486 CWETQVGQEMYKLMIFDFIIILAVTLFVDFPRKLLVTYCSSCKLIQCWGQQ-------EF 538
Query: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASR 615
I +NVL +VY Q + W+GAFFSP LPA LK I + Y++ W++L P + FRAS
Sbjct: 539 AIPDNVLGIVYGQTICWIGAFFSPLLPAIATLKFIIIFYVKEWSLLYTCRPSPRPFRASN 598
Query: 616 SNNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGS 675
SN F+L +LL L L ++P +I R S CGPF+ ++++ +T+ FP S
Sbjct: 599 SNFFFLLVLLIGLCLAIIPLTISISRIPSSKACGPFTNFNTTWEVIPKTVST-FPSSLQS 657
Query: 676 VVGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDK 726
+ ++S +P +++ ++++Y ++A + K QL+ Q+ + S DK
Sbjct: 658 FIHGVTSEAFAVPFFMIICLIMFYFIALAGAHKRVVIQLREQL-SLESRDK 707
Score = 127 bits (320), Expect = 4e-29
Identities = 97/373 (26%), Positives = 166/373 (44%), Gaps = 33/373 (8%)
Query: 76 RALRQAKNIVLKFEGRLTRTRGYQAAGAELWRKFARLACNFVVIFIPWEMRIKKIESHFG 135
R LR + +K+ + + Y + W++F A W I+ IE FG
Sbjct: 101 RRLRDIQETQMKYLSEWDQWKRYSSKS---WKRFLEKAREMTTHLELWREDIRSIEGKFG 157
Query: 136 SGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTIPKEQVSSAQDLDT 195
+G+ SYF FLR+L +N+V+ ++ +++P L+ +++ IP + + +
Sbjct: 158 TGIQSYFSFLRFLVLLNLVIFLIIFMLVLLPVLLTKYKITNSSFVLIPFKDMDKQCTVYP 217
Query: 196 VWSLG---------------GYLQYSVLFYGYYGRER-KIGRAGYRLPLAYFLVGMAVFA 239
V S G G+L+ + LFYG+Y + K Y LPLAY L +A A
Sbjct: 218 VSSSGLIYFYSYIIDLLSGTGFLEETSLFYGHYTIDGVKFQNFTYDLPLAYLLSTIASLA 277
Query: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299
S + ++K+ + + +L + ++C ++F WD+ I N A+ K +++ +R
Sbjct: 278 LSLLWIVKRSVEGFKINLIRSEEHFQSYCNKIFAGWDFCITNRSMADLKHSSLRYELRAD 337
Query: 300 ILEEQEKKK-----SKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKEL 354
+ EE+ ++K S+ LR+ N +VL L Y IY SQ E KKE+
Sbjct: 338 LEEERMRQKIAERTSEETIRIYSLRLFLNCIVLAVLGACFYAIYVATVFSQ--EHMKKEI 395
Query: 355 TLWEKNE-------VSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNL 407
E S+V++L I P F I E Y P +R + R + + L +
Sbjct: 396 DKMVFGENLFILYLPSIVITLANFITPMIFAKIIRYEDYSPGFEIRLTILRCVFMRLATI 455
Query: 408 YSLIIALLDKVNS 420
L+ L K+ S
Sbjct: 456 CVLVFTLGSKITS 468
>gi|21389589 transmembrane channel-like 4 isoform 2 [Homo sapiens]
Length = 706
Score = 122 bits (305), Expect = 2e-27
Identities = 77/242 (31%), Positives = 125/242 (51%), Gaps = 7/242 (2%)
Query: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIA 558
CWET +GQEM KL + D+L +A LLI F R L C + EF++
Sbjct: 469 CWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGL-----CPGALGRLAGTQEFQVP 523
Query: 559 ENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNN 618
+ VL L+Y Q ++W+G+FF P LP N +K + L YL+ + + P + FRAS +N
Sbjct: 524 DEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANF 583
Query: 619 FYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVG 678
F+ +LL L + +P +++I PS CGPF GQ I+ + E+I P + +
Sbjct: 584 FFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESI-SSLPETTQNFLF 642
Query: 679 HISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQ 738
+ + +P +L+ +L+ Y ++A S +LK Q Q +++K +A+ A
Sbjct: 643 FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQ-TEAQNKVFLARRAVALTS 701
Query: 739 TQ 740
T+
Sbjct: 702 TK 703
Score = 103 bits (257), Expect = 9e-22
Identities = 81/316 (25%), Positives = 142/316 (44%), Gaps = 26/316 (8%)
Query: 122 PWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFG------ 175
PW +K+I FG+G SYF LR+L +N++ +++ ++P + G P G
Sbjct: 138 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 197
Query: 176 -STARKTIPKEQ--VSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFL 232
S P Q V+ A L + S GYL++S LFYG+Y RL + Y
Sbjct: 198 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 250
Query: 233 VGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAI 292
AV +++L + + +L + S ++ RVF AWD+ + + I
Sbjct: 251 WAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQRII 310
Query: 293 VNSIR----EAILEEQEKKKSKNLAVTICL-RIIANILVLLSLAGSIYLIYFVVDRSQKL 347
+ ++ E ++ Q ++ + L R++ N+LV+ L + Y +Y+ + +L
Sbjct: 311 LYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTVEL 370
Query: 348 E-----QSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVL 402
+ Q L L S+ ++ V + P F LIA LE Y + F L R + L
Sbjct: 371 QEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFL 430
Query: 403 YLGNLYSLIIALLDKV 418
L +L L+ +L +++
Sbjct: 431 RLASLVVLLFSLWNQI 446
>gi|223718080 transmembrane channel-like 4 isoform 1 [Homo sapiens]
Length = 712
Score = 122 bits (305), Expect = 2e-27
Identities = 77/242 (31%), Positives = 125/242 (51%), Gaps = 7/242 (2%)
Query: 499 CWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEFKIA 558
CWET +GQEM KL + D+L +A LLI F R L C + EF++
Sbjct: 475 CWETVLGQEMYKLLLFDLLTVLAVALLIQFPRKLLCGL-----CPGALGRLAGTQEFQVP 529
Query: 559 ENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRSNN 618
+ VL L+Y Q ++W+G+FF P LP N +K + L YL+ + + P + FRAS +N
Sbjct: 530 DEVLGLIYAQTVVWVGSFFCPLLPLLNTVKFLLLFYLKKLTLFSTCSPAARTFRASAANF 589
Query: 619 FYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVG 678
F+ +LL L + +P +++I PS CGPF GQ I+ + E+I P + +
Sbjct: 590 FFPLVLLLGLAISSVPLLYSIFLIPPSKLCGPFRGQSSIWAQIPESI-SSLPETTQNFLF 648
Query: 679 HISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQ 738
+ + +P +L+ +L+ Y ++A S +LK Q Q +++K +A+ A
Sbjct: 649 FLGTQAFAVPLLLISSILMAYTVALANSYGRLISELKRQRQ-TEAQNKVFLARRAVALTS 707
Query: 739 TQ 740
T+
Sbjct: 708 TK 709
Score = 103 bits (257), Expect = 9e-22
Identities = 81/316 (25%), Positives = 142/316 (44%), Gaps = 26/316 (8%)
Query: 122 PWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFG------ 175
PW +K+I FG+G SYF LR+L +N++ +++ ++P + G P G
Sbjct: 144 PWAWTLKRIGGQFGAGTESYFSLLRFLLLLNVLASVLMACMTLLPTWLGGAPPGPPGPDI 203
Query: 176 -STARKTIPKEQ--VSSAQDLDTVWSLGGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFL 232
S P Q V+ A L + S GYL++S LFYG+Y RL + Y
Sbjct: 204 SSPCGSYNPHSQGLVTFATQLFNLLSGEGYLEWSPLFYGFYPPRP-------RLAVTYLC 256
Query: 233 VGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAI 292
AV +++L + + +L + S ++ RVF AWD+ + + I
Sbjct: 257 WAFAVGLICLLLILHRSVSGLKQTLLAESEALTSYSHRVFSAWDFGLCGDVHVRLRQRII 316
Query: 293 VNSIR----EAILEEQEKKKSKNLAVTICL-RIIANILVLLSLAGSIYLIYFVVDRSQKL 347
+ ++ E ++ Q ++ + L R++ N+LV+ L + Y +Y+ + +L
Sbjct: 317 LYELKVELEETVVRRQAAVRTLGQQARVWLVRVLLNLLVVALLGAAFYGVYWATGCTVEL 376
Query: 348 E-----QSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVL 402
+ Q L L S+ ++ V + P F LIA LE Y + F L R + L
Sbjct: 377 QEMPLVQELPLLKLGVNYLPSIFIAGVNFVLPPVFKLIAPLEGYTRSRQIVFILLRTVFL 436
Query: 403 YLGNLYSLIIALLDKV 418
L +L L+ +L +++
Sbjct: 437 RLASLVVLLFSLWNQI 452
>gi|23943900 transmembrane channel-like 8 [Homo sapiens]
Length = 726
Score = 108 bits (271), Expect = 2e-23
Identities = 66/222 (29%), Positives = 109/222 (49%), Gaps = 7/222 (3%)
Query: 498 QCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFV-RYLSDYWCWDLESKFPEYGEFK 556
QCWE VG+E+ KLSI + L TVA L+ R L V R+ +W W E EF
Sbjct: 417 QCWENSVGEELYKLSIFNFLLTVAFAFLVTLPRRLLVDRFSGRFWAW------LEREEFL 470
Query: 557 IAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRASRS 616
+ +NVL +V Q + WMG F+ P LP N + L Y++ + +L + + FRAS S
Sbjct: 471 VPKNVLDIVAGQTVTWMGLFYCPLLPLLNSVFLFLTFYIKKYTLLKNSRASSRPFRASSS 530
Query: 617 NNFYLAMLLFMLFLCMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSV 676
F+ +LL L L +P + + S +CG F+ + +V E + P
Sbjct: 531 TFFFQLVLLLGLLLAAVPLGYVVSSIHSSWDCGLFTNYSAPWQVVPELVALGLPPIGQRA 590
Query: 677 VGHISSPVVILPAVLLLFMLIYYLQSIARSLKLSNHQLKMQI 718
+ ++ S P +++L +++ S ++ + H+L+ Q+
Sbjct: 591 LHYLGSHAFSFPLLIMLSLVLTVCVSQTQANARAIHRLRKQL 632
Score = 90.5 bits (223), Expect = 8e-18
Identities = 85/307 (27%), Positives = 139/307 (45%), Gaps = 20/307 (6%)
Query: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPF-GSTARKT 181
WE + +I FG+G+ SYF FLR+L +N++ ++T +F+++P + P G T T
Sbjct: 91 WEGALYEIGGLFGTGIRSYFTFLRFLLLLNLLSLLLTASFVLLPLVWLRPPDPGPTLNLT 150
Query: 182 I--PKEQVSSAQDL---DTVWSL--GGYLQYSVLFYGYYGRERKIGRAGYRLPLAYFLVG 234
+ P + S L + +W + G + LFYG Y R + Y + LAY L
Sbjct: 151 LQCPGSRQSPPGVLRFHNQLWHVLTGRAFTNTYLFYGAY-RVGPESSSVYSIRLAYLLSP 209
Query: 235 MAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVN 294
+A F L++M K +VF +WD+ I EAA K I N
Sbjct: 210 LACLLLCFCGTLRRMVKGLPQKTLLGQGYQAPLSAKVFSSWDFCIRVQEAATIKKHEISN 269
Query: 295 SIREAILEEQ--EKKKSKNLAVTIC-----LRIIANILVLLSLAGSIYLIYFVVDRSQKL 347
+ + E + + + + A T C LR+ N+L L + G+I I++ SQ
Sbjct: 270 EFKVELEEGRRFQLMQQQTRAQTACRLLSYLRV--NVLNGLLVVGAISAIFWATKYSQ-- 325
Query: 348 EQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMYHPRTTLRFQLARVLVLYLGNL 407
+ ++ L L + V++LV + P F + LE Y P T + L +VL L +L
Sbjct: 326 DNKEESLFLLLQYLPPGVIALVNFLGPLLFTFLVQLENYPPNTEVNLTLIWCVVLKLASL 385
Query: 408 YSLIIAL 414
++L
Sbjct: 386 GMFSVSL 392
>gi|157426860 transmembrane channel-like 5 isoform a [Homo sapiens]
Length = 1006
Score = 103 bits (258), Expect = 7e-22
Identities = 75/261 (28%), Positives = 127/261 (48%), Gaps = 23/261 (8%)
Query: 497 DQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYG--E 554
++CWET +GQ++ +L ++D +F++ + L +F R + L G E
Sbjct: 722 EECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQL-----------ITSLGLQE 770
Query: 555 FKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRAS 614
F IA NVL L+Y Q ++W+G FF P LP ++ L + Y ++ +++ P + +RAS
Sbjct: 771 FDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRAS 830
Query: 615 RSNNFYLAMLLFMLFLCMLPTI-FAIVRYKPSLNCGPFSGQ----EKIYDIVSETIEKDF 669
+ F++ +L F F +L T+ I R KPS +CGPF G IY + +
Sbjct: 831 QMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPG 890
Query: 670 PVWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDKKK 728
+W + ++ V + L+ ++I YL I K+ L QI N E K K
Sbjct: 891 YLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIIN---EGKDK 947
Query: 729 VAQMVEARIQTQEESTKKLPN 749
+ ++E I+ Q+ K P+
Sbjct: 948 MF-LIEKLIKLQDMEKKANPS 967
Score = 79.7 bits (195), Expect = 1e-14
Identities = 78/310 (25%), Positives = 128/310 (41%), Gaps = 24/310 (7%)
Query: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTI 182
W+ +K I FG+ V SYF FLRWL NI I+ +FI+IP+ T+
Sbjct: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQF------------TV 478
Query: 183 PKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGR---ERKIGRAGYRLPLAYFLVGMAVFA 239
K+ L+ + GY + +V++YG+Y + A Y + LAY A
Sbjct: 479 AKKNTLQFTGLEFFTGV-GYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLT 537
Query: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299
F LL MAK R + + + +FC WD+ + + +A + K + IRE
Sbjct: 538 TCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIREN 596
Query: 300 ILE---EQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTL 356
+ E E K L ++A ++ +Y++ + LE K
Sbjct: 597 LSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAE--YNLEFLKTHSNP 654
Query: 357 WEKNEVSVVVSLVTMIAPSAFDLIAALEMYH-PRTTLRFQLARVLVLYLGNLYSLIIALL 415
+ VVS + + P + + +E Y PR + L R + L + + L L
Sbjct: 655 GAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWL 714
Query: 416 DKVNSMSIEE 425
+ V ++S EE
Sbjct: 715 NTV-ALSGEE 723
>gi|31377679 transmembrane channel-like 5 isoform c [Homo sapiens]
Length = 760
Score = 103 bits (258), Expect = 7e-22
Identities = 75/261 (28%), Positives = 127/261 (48%), Gaps = 23/261 (8%)
Query: 497 DQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYG--E 554
++CWET +GQ++ +L ++D +F++ + L +F R + L G E
Sbjct: 476 EECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQL-----------ITSLGLQE 524
Query: 555 FKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRAS 614
F IA NVL L+Y Q ++W+G FF P LP ++ L + Y ++ +++ P + +RAS
Sbjct: 525 FDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRAS 584
Query: 615 RSNNFYLAMLLFMLFLCMLPTI-FAIVRYKPSLNCGPFSGQ----EKIYDIVSETIEKDF 669
+ F++ +L F F +L T+ I R KPS +CGPF G IY + +
Sbjct: 585 QMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPG 644
Query: 670 PVWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDKKK 728
+W + ++ V + L+ ++I YL I K+ L QI N E K K
Sbjct: 645 YLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIIN---EGKDK 701
Query: 729 VAQMVEARIQTQEESTKKLPN 749
+ ++E I+ Q+ K P+
Sbjct: 702 MF-LIEKLIKLQDMEKKANPS 721
Score = 79.7 bits (195), Expect = 1e-14
Identities = 78/310 (25%), Positives = 128/310 (41%), Gaps = 24/310 (7%)
Query: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTI 182
W+ +K I FG+ V SYF FLRWL NI I+ +FI+IP+ T+
Sbjct: 185 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQF------------TV 232
Query: 183 PKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGR---ERKIGRAGYRLPLAYFLVGMAVFA 239
K+ L+ + GY + +V++YG+Y + A Y + LAY A
Sbjct: 233 AKKNTLQFTGLEFFTGV-GYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLT 291
Query: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299
F LL MAK R + + + +FC WD+ + + +A + K + IRE
Sbjct: 292 TCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIREN 350
Query: 300 ILE---EQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTL 356
+ E E K L ++A ++ +Y++ + LE K
Sbjct: 351 LSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAE--YNLEFLKTHSNP 408
Query: 357 WEKNEVSVVVSLVTMIAPSAFDLIAALEMYH-PRTTLRFQLARVLVLYLGNLYSLIIALL 415
+ VVS + + P + + +E Y PR + L R + L + + L L
Sbjct: 409 GAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWL 468
Query: 416 DKVNSMSIEE 425
+ V ++S EE
Sbjct: 469 NTV-ALSGEE 477
>gi|187608784 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 97.1 bits (240), Expect = 8e-20
Identities = 74/239 (30%), Positives = 117/239 (48%), Gaps = 19/239 (7%)
Query: 496 QDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEF 555
Q QCWE +VGQE+ + ++D + +LL F L R +S+ + K EF
Sbjct: 537 QGQCWEDFVGQELYRFLVMDFVL----MLLDTLFGELVWRIISEK-----KLKRRRKPEF 587
Query: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVL-TCNVPHQQVFRAS 614
IA NVL L+Y Q + W+G FSP LPA ++KL+ + Y++ ++L C P ++ + AS
Sbjct: 588 DIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAP-RRPWLAS 646
Query: 615 RSNNFYLAMLLFMLFL-CMLPTIFAIVRYKPSLNCGPFSGQEKIYD---IVSETIEKDFP 670
+ +L +L F FL + +A+ + KPS CGPF + +Y+ + +E P
Sbjct: 647 HMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGP 706
Query: 671 --VWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDK 726
W V ++ + V L + + YL + R + LK QI N EDK
Sbjct: 707 RVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISN-EGEDK 764
Score = 79.3 bits (194), Expect = 2e-14
Identities = 76/311 (24%), Positives = 132/311 (42%), Gaps = 35/311 (11%)
Query: 121 IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK 180
+PW +K+I FGS V SYF+FL+ L N +L ++ AFI+ P++ A
Sbjct: 228 MPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV 287
Query: 181 TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRER----------------KIGRAGY 224
E ++ A G ++V++YG+Y ++G Y
Sbjct: 288 CTGLELLTGA----------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPY 337
Query: 225 RLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEA 284
+PLAY F + I L+ MA + S S VFC+WDY + A
Sbjct: 338 NMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSG-IHAITVFCSWDYKVTQKRA 396
Query: 285 AESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLL----SLAGSIYLIYFV 340
+ + I ++E + E Q + +++ + + ++ LL +L ++ + F
Sbjct: 397 SRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFS 456
Query: 341 VDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMY-HPRTTLRFQLARV 399
Q E + +E L + +VV L+ + AP ++AALE + P + + R
Sbjct: 457 EFMIQSPEAAGQEAVLL---VLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRN 513
Query: 400 LVLYLGNLYSL 410
L+L L L +L
Sbjct: 514 LILKLAILGTL 524
>gi|187608791 transmembrane channel-like 6 [Homo sapiens]
Length = 805
Score = 97.1 bits (240), Expect = 8e-20
Identities = 74/239 (30%), Positives = 117/239 (48%), Gaps = 19/239 (7%)
Query: 496 QDQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYGEF 555
Q QCWE +VGQE+ + ++D + +LL F L R +S+ + K EF
Sbjct: 537 QGQCWEDFVGQELYRFLVMDFVL----MLLDTLFGELVWRIISEK-----KLKRRRKPEF 587
Query: 556 KIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVL-TCNVPHQQVFRAS 614
IA NVL L+Y Q + W+G FSP LPA ++KL+ + Y++ ++L C P ++ + AS
Sbjct: 588 DIARNVLELIYGQTLTWLGVLFSPLLPAVQIIKLLLVFYVKKTSLLANCQAP-RRPWLAS 646
Query: 615 RSNNFYLAMLLFMLFL-CMLPTIFAIVRYKPSLNCGPFSGQEKIYD---IVSETIEKDFP 670
+ +L +L F FL + +A+ + KPS CGPF + +Y+ + +E P
Sbjct: 647 HMSTVFLTLLCFPAFLGAAVFLCYAVWQVKPSSTCGPFRTLDTMYEAGRVWVRHLEAAGP 706
Query: 671 --VWFGSVVGHISSPVVILPAVLLLFMLIYYLQ-SIARSLKLSNHQLKMQIQNARSEDK 726
W V ++ + V L + + YL + R + LK QI N EDK
Sbjct: 707 RVSWLPWVHRYLMENTFFVFLVSALLLAVIYLNIQVVRGQRKVICLLKEQISN-EGEDK 764
Score = 79.3 bits (194), Expect = 2e-14
Identities = 76/311 (24%), Positives = 132/311 (42%), Gaps = 35/311 (11%)
Query: 121 IPWEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARK 180
+PW +K+I FGS V SYF+FL+ L N +L ++ AFI+ P++ A
Sbjct: 228 MPWRYALKRIGGQFGSSVLSYFLFLKTLLAFNALLLLLLVAFIMGPQVAFPPALPGPAPV 287
Query: 181 TIPKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGRER----------------KIGRAGY 224
E ++ A G ++V++YG+Y ++G Y
Sbjct: 288 CTGLELLTGA----------GCFTHTVMYYGHYSNATLNQPCGSPLDGSQCTPRVGGLPY 337
Query: 225 RLPLAYFLVGMAVFAYSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEA 284
+PLAY F + I L+ MA + S S VFC+WDY + A
Sbjct: 338 NMPLAYLSTVGVSFFITCITLVYSMAHSFGESYRVGSTSG-IHAITVFCSWDYKVTQKRA 396
Query: 285 AESKTAAIVNSIREAILEEQEKKKSKNLAVTICLRIIANILVLL----SLAGSIYLIYFV 340
+ + I ++E + E Q + +++ + + ++ LL +L ++ + F
Sbjct: 397 SRLQQDNIRTRLKELLAEWQLRHSPRSVCGRLRQAAVLGLVWLLCLGTALGCAVAVHVFS 456
Query: 341 VDRSQKLEQSKKELTLWEKNEVSVVVSLVTMIAPSAFDLIAALEMY-HPRTTLRFQLARV 399
Q E + +E L + +VV L+ + AP ++AALE + P + + R
Sbjct: 457 EFMIQSPEAAGQEAVLL---VLPLVVGLLNLGAPYLCRVLAALEPHDSPVLEVYVAICRN 513
Query: 400 LVLYLGNLYSL 410
L+L L L +L
Sbjct: 514 LILKLAILGTL 524
>gi|157426862 transmembrane channel-like 5 isoform b [Homo sapiens]
Length = 948
Score = 82.4 bits (202), Expect = 2e-15
Identities = 48/152 (31%), Positives = 82/152 (53%), Gaps = 17/152 (11%)
Query: 497 DQCWETYVGQEMLKLSIIDMLFTVASILLIDFFRGLFVRYLSDYWCWDLESKFPEYG--E 554
++CWET +GQ++ +L ++D +F++ + L +F R + L G E
Sbjct: 722 EECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQL-----------ITSLGLQE 770
Query: 555 FKIAENVLHLVYNQGMIWMGAFFSPCLPAFNVLKLIGLMYLRSWAVLTCNVPHQQVFRAS 614
F IA NVL L+Y Q ++W+G FF P LP ++ L + Y ++ +++ P + +RAS
Sbjct: 771 FDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRAS 830
Query: 615 RSNNFYLAMLLFMLF---LCMLP-TIFAIVRY 642
+ F++ +L F F LC L TI+ I+ Y
Sbjct: 831 QMMTFFIFLLFFPSFTGVLCTLAITIWRIITY 862
Score = 79.7 bits (195), Expect = 1e-14
Identities = 78/310 (25%), Positives = 128/310 (41%), Gaps = 24/310 (7%)
Query: 123 WEMRIKKIESHFGSGVASYFIFLRWLFGINIVLTIMTGAFIVIPELIAGQPFGSTARKTI 182
W+ +K I FG+ V SYF FLRWL NI I+ +FI+IP+ T+
Sbjct: 431 WQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQF------------TV 478
Query: 183 PKEQVSSAQDLDTVWSLGGYLQYSVLFYGYYGR---ERKIGRAGYRLPLAYFLVGMAVFA 239
K+ L+ + GY + +V++YG+Y + A Y + LAY A
Sbjct: 479 AKKNTLQFTGLEFFTGV-GYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLT 537
Query: 240 YSFIILLKKMAKNSRTSLASASNENYTFCWRVFCAWDYLIGNPEAAESKTAAIVNSIREA 299
F LL MAK R + + + +FC WD+ + + +A + K + IRE
Sbjct: 538 TCFFSLLFSMAKYFRNNFINPHIYSGGITKLIFC-WDFTVTHEKAVKLKQKNLSTEIREN 596
Query: 300 ILE---EQEKKKSKNLAVTICLRIIANILVLLSLAGSIYLIYFVVDRSQKLEQSKKELTL 356
+ E E K L ++A ++ +Y++ + LE K
Sbjct: 597 LSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAE--YNLEFLKTHSNP 654
Query: 357 WEKNEVSVVVSLVTMIAPSAFDLIAALEMYH-PRTTLRFQLARVLVLYLGNLYSLIIALL 415
+ VVS + + P + + +E Y PR + L R + L + + L L
Sbjct: 655 GAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWL 714
Query: 416 DKVNSMSIEE 425
+ V ++S EE
Sbjct: 715 NTV-ALSGEE 723
>gi|32484977 angiomotin like 2 [Homo sapiens]
Length = 780
Score = 43.5 bits (101), Expect = 0.001
Identities = 48/166 (28%), Positives = 64/166 (38%), Gaps = 23/166 (13%)
Query: 788 AQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYL-HGLCASTSD------LHRNRSRTP 840
AQ P GDR P G SR + E R L HG S S+ L RN +R P
Sbjct: 119 AQQAGTRPHAGDRDPRGAPGG---SRRQDEALRELRHGHVRSLSERLLQLSLERNGARAP 175
Query: 841 MTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINE-CDSYKKK 899
+H+ HS P ++ Q PP RGP A ++GP P P + +E +
Sbjct: 176 ----SHMSSSHSFPQLARNQQ--GPPLRGPPAEGPESRGPPPQYPHVVLAHETTTAVTDP 229
Query: 900 HLNVWPERHFK------IDASGDIVELYPRNVRQYASRVPRQPPSP 939
HF+ + A V L + QY + PP P
Sbjct: 230 RYRARGSPHFQHAEVRILQAQVPPVFLQQQQQYQYLQQSQEHPPPP 275
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 39.3 bits (90), Expect = 0.021
Identities = 42/169 (24%), Positives = 69/169 (40%), Gaps = 17/169 (10%)
Query: 880 PRPHAPRYYVINECDSYKKKHLNVWPERHFKID--ASGDIVELYPRNVRQYASRVPRQPP 937
P P + + + +K+ + W E + D A L PR + Q
Sbjct: 327 PHPRSVIQQAEEKLHTPQKRLMTPWEESNVMQDKDAPSPKPRLSPRET--IFGKSEHQNS 384
Query: 938 SPQLSEEEEETPSRDWIKRSLPPRSLIDLRRAPHFYIG-ERSESQTRDPE----HQGRVH 992
SP E+EE+ R I SLPP + D ++G +++E D + + G +H
Sbjct: 385 SPTCQEDEEDV--RYNIVHSLPP-DINDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIH 441
Query: 993 YK-----SWNEDFEGHLERPAYVPRKPRSRNFQYPQPPLKPRGKPRFEP 1036
+ E+ EG E+P+Y P P S+ +Q +P PR + P
Sbjct: 442 AELVVIDDEEEEDEGEAEKPSYHPIAPHSQVYQPAKPTPLPRKRSEASP 490
>gi|83367069 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 10/129 (7%)
Query: 699 YLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLS 758
Y+ +I +S + +++ K + A S D K V+ + EAR Q E ST + S L L+
Sbjct: 469 YIDTIPQSSRSPSYRTKAKSHGALS-DSKSVSNLSEARAQIAEPSTSRYFPSSCL--DLN 525
Query: 759 SAHSGTPQNNGNVAHFDSGSSKSGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHET 818
S S TP + + S S ++ R E S + R LP EH
Sbjct: 526 SPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLP-------EHMD 578
Query: 819 NRYLHGLCA 827
+ + H L A
Sbjct: 579 SSHSHSLSA 587
>gi|4507281 cyclin-dependent kinase-like 5 [Homo sapiens]
Length = 1030
Score = 38.5 bits (88), Expect = 0.035
Identities = 36/129 (27%), Positives = 55/129 (42%), Gaps = 10/129 (7%)
Query: 699 YLQSIARSLKLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLS 758
Y+ +I +S + +++ K + A S D K V+ + EAR Q E ST + S L L+
Sbjct: 469 YIDTIPQSSRSPSYRTKAKSHGALS-DSKSVSNLSEARAQIAEPSTSRYFPSSCL--DLN 525
Query: 759 SAHSGTPQNNGNVAHFDSGSSKSGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHET 818
S S TP + + S S ++ R E S + R LP EH
Sbjct: 526 SPTSPTPTRHSDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLP-------EHMD 578
Query: 819 NRYLHGLCA 827
+ + H L A
Sbjct: 579 SSHSHSLSA 587
>gi|54792782 C-type lectin domain family 16, member A [Homo sapiens]
Length = 1053
Score = 38.1 bits (87), Expect = 0.046
Identities = 20/58 (34%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 753 LTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQSMPQSPRPGDRAPSSPLPGVP 810
L+SQ + SG+P +G+ +H DSG + S + AQS +P +P P P +P
Sbjct: 896 LSSQSPPSASGSPSGSGSTSHCDSGGTSSSSTPSTAQSPADAP----MSPELPKPHLP 949
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 38.1 bits (87), Expect = 0.046
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 3/127 (2%)
Query: 942 SEEEEETPSRDWIKRSLPPRSLIDLRRAPHFYIG---ERSESQTRDPEHQGRVHYKSWNE 998
S E + + S++ +R+ D+ + H Y ERS S+ R + R H + +
Sbjct: 527 SNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSR 586
Query: 999 DFEGHLERPAYVPRKPRSRNFQYPQPPLKPRGKPRFEPSLTESDSVSAASSSDQQNSSAD 1058
E H R R+ RSR+ + PP + R K R S S S ++ +
Sbjct: 587 SKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRN 646
Query: 1059 QYLQVTH 1065
Q + +H
Sbjct: 647 QESKSSH 653
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 37.7 bits (86), Expect = 0.060
Identities = 70/323 (21%), Positives = 118/323 (36%), Gaps = 49/323 (15%)
Query: 789 QSMPQSPRPGDRAPSSP-------LPGVPKSRLEHETNRYL--------HGLCASTSDLH 833
+++PQ+PRP R+PSSP P +S E ++ S+ +L
Sbjct: 1487 KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 834 RNRSRTPMTFTTHIEDVHSEPLFRKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINEC 893
S +P + S+ R +Q + P+ + PR +
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR------SGS 1600
Query: 894 DSYKKKHLNVWPERHFKIDASGD----IVELYPRNVRQYASRVPRQPPSPQLSEEEEETP 949
K P D+S + PR R +S R P SP+ S E +P
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGP-SPEGSSSTESSP 1659
Query: 950 SRDWIKRSLPPRSLIDLRRAPHFYIGERSESQTRDPEHQGRVHYKSWNEDFEGHLERPAY 1009
PP+S R G RS + P+ + R + + L R A
Sbjct: 1660 EH-------PPKSRTARR-------GSRSSPE---PKTKSRTPPRRRSSRSSPELTRKAR 1702
Query: 1010 VPRKPRSRNFQYPQPPLKPRGKPRFE--PSLTESDSVSAASSSDQQNSSADQYLQVTHSQ 1067
+ R+ RS + P + R PR PS++ + + SS ++ S++ + T +
Sbjct: 1703 LSRRSRSAS---SSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRR 1759
Query: 1068 GRFPRSVGQP-SRRKAKSGQELT 1089
GR P + R +++S +E T
Sbjct: 1760 GRSPSPKPRGLQRSRSRSRREKT 1782
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 35.8 bits (81), Expect = 0.23
Identities = 38/159 (23%), Positives = 59/159 (37%), Gaps = 15/159 (9%)
Query: 940 QLSEEE----EETPSRDWIKRSLP--PRSLIDLRRAPHFYIGERSESQTRDPEHQGRVHY 993
QLS+ E E+TP + + P P+SL + + H E + D
Sbjct: 428 QLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESES 487
Query: 994 KSWNEDFEGHLERPAYVPRKPRSRNFQYP-------QPPLKPRGKPRFEPSL--TESDSV 1044
S + + LE PA P P + +Q QP P G EP ES
Sbjct: 488 SSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGS 547
Query: 1045 SAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRRKAK 1083
S +++S + + S D + + R P P +R +
Sbjct: 548 SDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQ 586
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 35.0 bits (79), Expect = 0.39
Identities = 87/429 (20%), Positives = 138/429 (32%), Gaps = 71/429 (16%)
Query: 708 KLSNHQLKMQIQNARSEDKKKVAQMVEARIQTQEESTKKLPNDSDLTSQLSSAHSGTPQN 767
++ +H K ARS +K + + Q++ S K N S T + +H+ +
Sbjct: 301 RVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSR-TPRRGRSHNWSRNP 359
Query: 768 NGNVAHFDSGSSKSGRIETVAQSMPQSPRPGDRAPSSPLPGVPKSRLEHETNRYLHGLCA 827
+ +H S SS R + S PR S G P + +H +R
Sbjct: 360 SKERSHSHSRSSSKERDHRGSSS----PRKESGRSQS---GSPNKQRDHSRSR------- 405
Query: 828 STSDLHRNRSRTPMTFTTHIEDVHSEPLFRKDFQQINPPH--------RGPQASTLLAQG 879
+ + R+RSR+ + P +D + P+ R P + ++
Sbjct: 406 -SPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRS 464
Query: 880 PRPHAPRYYVINECDSYKKKHLNVWP---------------ERHFKIDASGDIVELYPRN 924
P+ R + S ++ H + ER + S + R+
Sbjct: 465 RSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS 524
Query: 925 VRQYASRVPRQPPSPQL----------SEEEEE----TPSRDWIKRSLPPRSLIDLRRAP 970
R RQ SP SEE E +PS++ +R S RR
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584
Query: 971 HFYIGERSESQTRDPEHQG-----------RVHYKSWNEDFEGHLERPAYVPRKPRSRNF 1019
ER S++R P Q + H +S EG+ + ++
Sbjct: 585 RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
Query: 1020 QYPQPPLKPRGKPRFE-------PSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPR 1072
P+ P R R PS T S S S S Q S D T S+ P
Sbjct: 645 TVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPG 704
Query: 1073 SVGQPSRRK 1081
S K
Sbjct: 705 ERSSSSSSK 713
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 33.9 bits (76), Expect = 0.87
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
Query: 631 CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690
CM P + SL GP G+E +++ +D P W + G + +P+V L
Sbjct: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
Query: 691 LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725
L L L+ + + R + H L +Q A SE+
Sbjct: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 33.9 bits (76), Expect = 0.87
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
Query: 631 CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690
CM P + SL GP G+E +++ +D P W + G + +P+V L
Sbjct: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
Query: 691 LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725
L L L+ + + R + H L +Q A SE+
Sbjct: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
>gi|113430845 PREDICTED: similar to protein kinase, DNA-activated,
catalytic polypeptide [Homo sapiens]
Length = 4096
Score = 33.9 bits (76), Expect = 0.87
Identities = 26/95 (27%), Positives = 42/95 (44%), Gaps = 11/95 (11%)
Query: 631 CMLPTIFAIVRYKPSLNCGPFSGQEKIYDIVSETIEKDFPVWFGSVVGHISSPVVILPAV 690
CM P + SL GP G+E +++ +D P W + G + +P+V L
Sbjct: 2093 CMAPLTALVKHMHRSL--GPPQGEE-------DSVPRDLPSWMKFLHGKLGNPIVPLNIR 2143
Query: 691 LLLFMLIYYLQSIARSLKLSNHQLKMQIQNARSED 725
L L L+ + + R + H L +Q A SE+
Sbjct: 2144 LFLAKLVINTEEVFR--PYAKHWLSPLLQLAASEN 2176
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 33.9 bits (76), Expect = 0.87
Identities = 57/231 (24%), Positives = 75/231 (32%), Gaps = 36/231 (15%)
Query: 857 RKDFQQINPPHRGPQASTLLAQGPRPHAPRYYVINECDSYKKKHLNVWPERHFKIDASGD 916
R+ +++ N S+ ++ RP R +V N +++H P R
Sbjct: 482 RRQYRRQNQQSSSDSGSSSSSEDERPK--RSHVKNGEVGRRRRHS---PSRSASPSPRKR 536
Query: 917 IVELYPRNVRQYASRVPRQPPSPQLSEEEEETPSRDWIKRSLPPRSLIDLRRAPHFYIGE 976
E PR R+ R P PP+ + P R + PPR RR P
Sbjct: 537 QKETSPRGRRR---RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR-----RRTPSPPPRR 588
Query: 977 RSESQTR-DPEHQGRVHYKSWNEDFEGHLERPAYVPRKPRSRNFQYPQPPLKPRGKPRFE 1035
RS S R P Q R Y P P R P PP K R P
Sbjct: 589 RSPSPRRYSPPIQRR------------------YSPSPPPKRRTASPPPPPKRRASPSPP 630
Query: 1036 PSLTESDSVSAASSSDQQNSSADQYLQVTHSQGRFPRSVGQPSRRKAKSGQ 1086
P S S S L H +G P S R+A+S Q
Sbjct: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP----SRSTREARSPQ 677
>gi|199562283 retrotransposon-like 1 [Homo sapiens]
Length = 1358
Score = 33.5 bits (75), Expect = 1.1
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 35/162 (21%)
Query: 403 YLGNLYSLIIALLDKVNSMSIEEMATKNNT-------SHWID--STTFFATRTAPEEEKW 453
YL N I+ LL+ E++A+ NN HW+ S F PE++
Sbjct: 937 YLENTEEPIMILLNT------EDLASLNNDRLTVLLPGHWVFFFSHFNFDVMELPEQDGG 990
Query: 454 STSRPGMGLR-----RNNTWALEETSISAYTMPLIKANKTSLHTQSPQDQCWETYVGQEM 508
P LR + NT A + +++ P + ++ QD+ E + QE+
Sbjct: 991 RALPPVRNLRWRRAFQRNTAARQTLLLASRGFPRDPSTESGEEENEEQDELNEQILRQEL 1050
Query: 509 LKLSIIDML-------FTVASI--LLIDFFRGLFVRYLSDYW 541
L + ID + F++A I +++ FFRGL YW
Sbjct: 1051 LAMIPIDQILNSFLAHFSMAQIRAVILHFFRGLL------YW 1086
>gi|54112407 protein kinase CHK2 isoform c [Homo sapiens]
Length = 586
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 743 STKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQ----SMPQSPRPG 798
S + S + +SS+ + T N+ +H SG+ S +ETV+ S+P+ P
Sbjct: 24 SVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSS--LETVSTQELYSIPEDQEPE 81
Query: 799 DRAPSSPLPGVPKSRL 814
D+ P P P P +RL
Sbjct: 82 DQEPEEPTP-APWARL 96
>gi|22209009 protein kinase CHK2 isoform b [Homo sapiens]
Length = 514
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 743 STKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQ----SMPQSPRPG 798
S + S + +SS+ + T N+ +H SG+ S +ETV+ S+P+ P
Sbjct: 24 SVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSS--LETVSTQELYSIPEDQEPE 81
Query: 799 DRAPSSPLPGVPKSRL 814
D+ P P P P +RL
Sbjct: 82 DQEPEEPTP-APWARL 96
>gi|6005850 protein kinase CHK2 isoform a [Homo sapiens]
Length = 543
Score = 33.1 bits (74), Expect = 1.5
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 7/76 (9%)
Query: 743 STKKLPNDSDLTSQLSSAHSGTPQNNGNVAHFDSGSSKSGRIETVAQ----SMPQSPRPG 798
S + S + +SS+ + T N+ +H SG+ S +ETV+ S+P+ P
Sbjct: 24 SVTQSQGSSSQSQGISSSSTSTMPNSSQSSHSSSGTLSS--LETVSTQELYSIPEDQEPE 81
Query: 799 DRAPSSPLPGVPKSRL 814
D+ P P P P +RL
Sbjct: 82 DQEPEEPTP-APWARL 96
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,796,015
Number of Sequences: 37866
Number of extensions: 1979044
Number of successful extensions: 8440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 8257
Number of HSP's gapped (non-prelim): 210
length of query: 1100
length of database: 18,247,518
effective HSP length: 113
effective length of query: 987
effective length of database: 13,968,660
effective search space: 13787067420
effective search space used: 13787067420
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.