Guide to the Human Genome
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Search of human proteins with 32469495

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi...   786   0.0  
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...    76   6e-14
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...    76   6e-14
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...    76   6e-14
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]     74   2e-13
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]     72   1e-12
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]    67   2e-11
gi|14589851 potassium channel, subfamily K, member 2 isoform b [...    67   3e-11
gi|126365795 potassium channel, subfamily K, member 2 isoform c ...    67   3e-11
gi|62912487 potassium channel, subfamily K, member 2 isoform a [...    67   3e-11
gi|205360983 potassium channel, subfamily K, member 16 isoform 3...    63   4e-10
gi|205360973 potassium channel, subfamily K, member 16 isoform 4...    63   4e-10
gi|205360971 potassium channel, subfamily K, member 16 isoform 1...    63   4e-10
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ...    63   4e-10
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]     60   3e-09
gi|15718767 TRAAK [Homo sapiens]                                       58   1e-08
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]     58   1e-08
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]     52   1e-06
gi|205361107 potassium channel, subfamily K, member 17 isoform 2...    49   8e-06
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ...    49   8e-06
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H...    47   2e-05
gi|16118231 potassium channel, subfamily K, member 7 isoform A [...    47   2e-05
gi|16118235 potassium channel, subfamily K, member 7 isoform B [...    47   2e-05
gi|16118233 potassium channel, subfamily K, member 7 isoform B [...    47   2e-05
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi...    46   5e-05
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi...    40   0.003
gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]    38   0.013
gi|88758576 Shaw-related voltage-gated potassium channel protein...    37   0.030
gi|24497462 Shaw-related voltage-gated potassium channel protein...    37   0.030
gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]    37   0.039

>gi|32469495 potassium channel, subfamily K, member 18 [Homo
           sapiens]
          Length = 384

 Score =  786 bits (2031), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MEVSGHPQARRCCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK 60
           MEVSGHPQARRCCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK
Sbjct: 1   MEVSGHPQARRCCPEALGKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK 60

Query: 61  FLEELCRILNCSETVVEDRKQDLQGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYG 120
           FLEELCRILNCSETVVEDRKQDLQGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYG
Sbjct: 61  FLEELCRILNCSETVVEDRKQDLQGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYG 120

Query: 121 YIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKW 180
           YIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKW
Sbjct: 121 YIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFRKFPFFTRPLLSKW 180

Query: 181 CPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTL 240
           CPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTL
Sbjct: 181 CPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMELFERSHALEKQNTL 240

Query: 241 QLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAI 300
           QLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAI
Sbjct: 241 QLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCAAAI 300

Query: 301 LPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQN 360
           LPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQN
Sbjct: 301 LPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQN 360

Query: 361 RLIDIYKNVMLFFAKGKFYHLVKK 384
           RLIDIYKNVMLFFAKGKFYHLVKK
Sbjct: 361 RLIDIYKNVMLFFAKGKFYHLVKK 384


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 51/146 (34%), Positives = 72/146 (49%), Gaps = 12/146 (8%)

Query: 30  LVTYALVGAVVFSAIEDG-----QVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQ 84
           +V Y + G +VF A+E       +  +A +  EF +  + +C      ET+++     L 
Sbjct: 84  VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLR--DHVCVSPQELETLIQHA---LD 138

Query: 85  GHLQKVKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIP 142
                V P     N ++HW   S+ FF  TV +T+GYG I P T  GK  C+LYA+FGIP
Sbjct: 139 ADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIP 198

Query: 143 LMFLVLTDTGDILATILSTSYNRFRK 168
           L   +L   GD L TI   S  R  K
Sbjct: 199 LFGFLLAGIGDQLGTIFGKSIARVEK 224



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 258 LGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCA------AAILPFWETQLDFE 311
           LG +    I+ +++V ++ +     + +I+ I+F    C       A I  + E     E
Sbjct: 211 LGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALE 270

Query: 312 NAFYFCFVTLTTIGFGDTV 330
           +  YF  VTLTT+GFGD V
Sbjct: 271 S-IYFVVVTLTTVGFGDFV 288



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/42 (30%), Positives = 22/42 (52%)

Query: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEI 350
           D  +AF+F    +TTIG+G+         +F  +Y I G+ +
Sbjct: 158 DLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 199


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 51/146 (34%), Positives = 72/146 (49%), Gaps = 12/146 (8%)

Query: 30  LVTYALVGAVVFSAIEDG-----QVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQ 84
           +V Y + G +VF A+E       +  +A +  EF +  + +C      ET+++     L 
Sbjct: 84  VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLR--DHVCVSPQELETLIQHA---LD 138

Query: 85  GHLQKVKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIP 142
                V P     N ++HW   S+ FF  TV +T+GYG I P T  GK  C+LYA+FGIP
Sbjct: 139 ADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIP 198

Query: 143 LMFLVLTDTGDILATILSTSYNRFRK 168
           L   +L   GD L TI   S  R  K
Sbjct: 199 LFGFLLAGIGDQLGTIFGKSIARVEK 224



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 258 LGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCA------AAILPFWETQLDFE 311
           LG +    I+ +++V ++ +     + +I+ I+F    C       A I  + E     E
Sbjct: 211 LGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALE 270

Query: 312 NAFYFCFVTLTTIGFGDTV 330
           +  YF  VTLTT+GFGD V
Sbjct: 271 S-IYFVVVTLTTVGFGDFV 288



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/42 (30%), Positives = 22/42 (52%)

Query: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEI 350
           D  +AF+F    +TTIG+G+         +F  +Y I G+ +
Sbjct: 158 DLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 199


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 51/146 (34%), Positives = 72/146 (49%), Gaps = 12/146 (8%)

Query: 30  LVTYALVGAVVFSAIEDG-----QVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQ 84
           +V Y + G +VF A+E       +  +A +  EF +  + +C      ET+++     L 
Sbjct: 79  VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLR--DHVCVSPQELETLIQHA---LD 133

Query: 85  GHLQKVKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIP 142
                V P     N ++HW   S+ FF  TV +T+GYG I P T  GK  C+LYA+FGIP
Sbjct: 134 ADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIP 193

Query: 143 LMFLVLTDTGDILATILSTSYNRFRK 168
           L   +L   GD L TI   S  R  K
Sbjct: 194 LFGFLLAGIGDQLGTIFGKSIARVEK 219



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 258 LGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCA------AAILPFWETQLDFE 311
           LG +    I+ +++V ++ +     + +I+ I+F    C       A I  + E     E
Sbjct: 206 LGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALE 265

Query: 312 NAFYFCFVTLTTIGFGDTV 330
           +  YF  VTLTT+GFGD V
Sbjct: 266 S-IYFVVVTLTTVGFGDFV 283



 Score = 28.9 bits (63), Expect = 8.1
 Identities = 13/42 (30%), Positives = 22/42 (52%)

Query: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEI 350
           D  +AF+F    +TTIG+G+         +F  +Y I G+ +
Sbjct: 153 DLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 194


>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
          Length = 394

 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 48/145 (33%), Positives = 71/145 (48%), Gaps = 8/145 (5%)

Query: 24  LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83
           L  +    TY LVGA VF A+E    L+     E  +  +EL    N S+   E+    L
Sbjct: 9   LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQ--QELRARYNLSQGGYEE----L 62

Query: 84  QGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPL 143
           +  + ++KP        W F  S +F  TV +T+GYG+  P T  GK  CM YAL GIPL
Sbjct: 63  ERVVLRLKPH--KAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120

Query: 144 MFLVLTDTGDILATILSTSYNRFRK 168
             ++    G+ + T++    +R +K
Sbjct: 121 TLVMFQSLGERINTLVRYLLHRAKK 145



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 32/103 (31%), Positives = 50/103 (48%), Gaps = 13/103 (12%)

Query: 273 GQQVERLDIPLPIIALIVF----AYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGD 328
           G  + R D+ +  + LI F    + +   AA    +E    F+ A+Y+CF+TLTTIGFGD
Sbjct: 146 GLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQ-AYYYCFITLTTIGFGD 204

Query: 329 TVL--------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLI 363
            V           P +  F  +YI+ G+ ++     LV  R +
Sbjct: 205 YVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFM 247



 Score = 35.4 bits (80), Expect = 0.087
 Identities = 17/70 (24%), Positives = 33/70 (47%)

Query: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIY 366
           Q  F  +FYF    +TTIG+G          +F   Y ++G+ +  + F+ +  R+  + 
Sbjct: 77  QWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLV 136

Query: 367 KNVMLFFAKG 376
           + ++    KG
Sbjct: 137 RYLLHRAKKG 146



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 8/26 (30%), Positives = 16/26 (61%)

Query: 95  FNRTTHWSFLSSLFFCCTVFSTVGYG 120
           F+   HW+F  + ++C    +T+G+G
Sbjct: 178 FSHYEHWTFFQAYYYCFITLTTIGFG 203


>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
          Length = 374

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 47/137 (34%), Positives = 65/137 (47%), Gaps = 8/137 (5%)

Query: 32  TYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQGHLQKVK 91
           TY LVGA VF A+E    +      E EK   E  RI        ED +Q L+  + + +
Sbjct: 17  TYLLVGAAVFDALESDHEM-----REEEKLKAEEIRIKGKYNISSEDYRQ-LELVILQSE 70

Query: 92  PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDT 151
           P        W F  S +F  TV +T+GYG+  P T  GK  CM YA+ GIPL  ++    
Sbjct: 71  PH--RAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSL 128

Query: 152 GDILATILSTSYNRFRK 168
           G+ + T +     R +K
Sbjct: 129 GERMNTFVRYLLKRIKK 145



 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 8/62 (12%)

Query: 310 FENAFYFCFVTLTTIGFGDTVL--------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNR 361
           F +A+Y+CF+TLTTIGFGD V         + P +  F  +YI+VG+ ++     LV  R
Sbjct: 186 FFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLNLVVLR 245

Query: 362 LI 363
            +
Sbjct: 246 FL 247



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 15/56 (26%), Positives = 26/56 (46%)

Query: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRL 362
           Q  F  +FYF    +TTIG+G           F   Y ++G+ +  + F+ +  R+
Sbjct: 77  QWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERM 132



 Score = 32.3 bits (72), Expect = 0.74
 Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 1/66 (1%)

Query: 95  FNRTTHWSFLSSLFFCCTVFSTVGYG-YIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGD 153
           F++   WSF  + ++C    +T+G+G Y+   T+       LY  F    + + LT  G 
Sbjct: 178 FSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGA 237

Query: 154 ILATIL 159
            L  ++
Sbjct: 238 FLNLVV 243


>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
          Length = 330

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 12/136 (8%)

Query: 24  LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83
           LC LC+L    LVGA VF A+E       A+ G     +++   +        ED ++ L
Sbjct: 13  LCTLCYL----LVGAAVFDALES-----EAESGRQRLLVQKRGALRRKFGFSAEDYRE-L 62

Query: 84  QGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPL 143
           +    + +P    R   W F  S +F  TV +T+GYG+  P T  GK  CM YAL GIPL
Sbjct: 63  ERLALQAEPHRAGR--QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120

Query: 144 MFLVLTDTGDILATIL 159
             +     G+ L  ++
Sbjct: 121 TLVTFQSLGERLNAVV 136



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 13/89 (14%)

Query: 288 LIVFAYISCAAAILPFWETQLDFE-----NAFYFCFVTLTTIGFGDTV-------LEHPN 335
           L+V   ++CAA +         FE     +A+Y+CF+TLTTIGFGD V       L+   
Sbjct: 159 LVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKL 218

Query: 336 FFLFFS-IYIIVGMEIVFIAFKLVQNRLI 363
            ++ FS +YI++G+ ++     LV  R +
Sbjct: 219 PYVAFSFLYILLGLTVIGAFLNLVVLRFL 247



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 17/65 (26%), Positives = 33/65 (50%)

Query: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIY 366
           Q  F  +FYF    +TTIG+G       +  +F   Y ++G+ +  + F+ +  RL  + 
Sbjct: 77  QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVV 136

Query: 367 KNVML 371
           + ++L
Sbjct: 137 RRLLL 141


>gi|14589851 potassium channel, subfamily K, member 2 isoform b
           [Homo sapiens]
          Length = 411

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 30  LVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETVVEDRKQDLQGHL 87
           +V Y ++GA VF A+E    +        +K  F+ +   +   + T +++  Q +   +
Sbjct: 54  VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCV---NSTELDELIQQIVAAI 110

Query: 88  QK-VKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLM 144
              + P     N+ +HW   SS FF  TV +T+G+G I P T  GK  C++YAL GIPL 
Sbjct: 111 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 170

Query: 145 FLVLTDTGDILATI 158
             +L   GD L TI
Sbjct: 171 GFLLAGVGDQLGTI 184



 Score = 32.7 bits (73), Expect = 0.56
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 31/127 (24%)

Query: 229 ERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIAL 288
           E+ H + ++ T+ +  Q     +SC             + LDE+ QQ         I+A 
Sbjct: 69  EQPHEISQRTTIVIQKQTFISQHSCVNS----------TELDELIQQ---------IVAA 109

Query: 289 IVFAYISCAAAILPFWETQ-----LDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIY 343
           I        A I+P   T       D  ++F+F    +TTIGFG+         +F  IY
Sbjct: 110 I-------NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 162

Query: 344 IIVGMEI 350
            ++G+ +
Sbjct: 163 ALLGIPL 169



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 6/43 (13%)

Query: 312 NAFYFCFVTLTTIGFGDTV-----LEHPNFFL-FFSIYIIVGM 348
           +A YF  +TLTTIGFGD V     +E+ +F+      +I+VG+
Sbjct: 240 DAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGL 282


>gi|126365795 potassium channel, subfamily K, member 2 isoform c
           [Homo sapiens]
          Length = 426

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 30  LVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETVVEDRKQDLQGHL 87
           +V Y ++GA VF A+E    +        +K  F+ +   +   + T +++  Q +   +
Sbjct: 69  VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCV---NSTELDELIQQIVAAI 125

Query: 88  QK-VKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLM 144
              + P     N+ +HW   SS FF  TV +T+G+G I P T  GK  C++YAL GIPL 
Sbjct: 126 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 185

Query: 145 FLVLTDTGDILATI 158
             +L   GD L TI
Sbjct: 186 GFLLAGVGDQLGTI 199



 Score = 32.7 bits (73), Expect = 0.56
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 31/127 (24%)

Query: 229 ERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIAL 288
           E+ H + ++ T+ +  Q     +SC             + LDE+ QQ         I+A 
Sbjct: 84  EQPHEISQRTTIVIQKQTFISQHSCVNS----------TELDELIQQ---------IVAA 124

Query: 289 IVFAYISCAAAILPFWETQ-----LDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIY 343
           I        A I+P   T       D  ++F+F    +TTIGFG+         +F  IY
Sbjct: 125 I-------NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 177

Query: 344 IIVGMEI 350
            ++G+ +
Sbjct: 178 ALLGIPL 184



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 6/43 (13%)

Query: 312 NAFYFCFVTLTTIGFGDTV-----LEHPNFFL-FFSIYIIVGM 348
           +A YF  +TLTTIGFGD V     +E+ +F+      +I+VG+
Sbjct: 255 DAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGL 297


>gi|62912487 potassium channel, subfamily K, member 2 isoform a
           [Homo sapiens]
          Length = 422

 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 44/134 (32%), Positives = 68/134 (50%), Gaps = 8/134 (5%)

Query: 30  LVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETVVEDRKQDLQGHL 87
           +V Y ++GA VF A+E    +        +K  F+ +   +   + T +++  Q +   +
Sbjct: 65  VVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCV---NSTELDELIQQIVAAI 121

Query: 88  QK-VKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLM 144
              + P     N+ +HW   SS FF  TV +T+G+G I P T  GK  C++YAL GIPL 
Sbjct: 122 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 181

Query: 145 FLVLTDTGDILATI 158
             +L   GD L TI
Sbjct: 182 GFLLAGVGDQLGTI 195



 Score = 32.7 bits (73), Expect = 0.56
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 31/127 (24%)

Query: 229 ERSHALEKQNTLQLPPQAMERSNSCPELVLGRLSYSIISNLDEVGQQVERLDIPLPIIAL 288
           E+ H + ++ T+ +  Q     +SC             + LDE+ QQ         I+A 
Sbjct: 80  EQPHEISQRTTIVIQKQTFISQHSCVNS----------TELDELIQQ---------IVAA 120

Query: 289 IVFAYISCAAAILPFWETQ-----LDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIY 343
           I        A I+P   T       D  ++F+F    +TTIGFG+         +F  IY
Sbjct: 121 I-------NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIY 173

Query: 344 IIVGMEI 350
            ++G+ +
Sbjct: 174 ALLGIPL 180



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 18/43 (41%), Positives = 27/43 (62%), Gaps = 6/43 (13%)

Query: 312 NAFYFCFVTLTTIGFGDTV-----LEHPNFFL-FFSIYIIVGM 348
           +A YF  +TLTTIGFGD V     +E+ +F+      +I+VG+
Sbjct: 251 DAIYFVVITLTTIGFGDYVAGGSDIEYLDFYKPVVWFWILVGL 293


>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
           [Homo sapiens]
          Length = 294

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 18  GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75
           G++ P    L   V Y L+GA +F  +E      + D  + EK  FLE    +    +  
Sbjct: 12  GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65

Query: 76  VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133
           +E   Q + +  ++ V P+  +   ++W F SS FF  TV +T+GYG + P T  G+  C
Sbjct: 66  MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125

Query: 134 MLYALFGIPLMFLVLTDTG 152
           + YAL GIPL  + L   G
Sbjct: 126 VFYALLGIPLNVIFLNHLG 144



 Score = 36.6 bits (83), Expect = 0.039
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHP 334
           QV  L + L +  L++  +     + +  W     F   FYF F+TL+TIGFGD V+   
Sbjct: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVVGTD 223

Query: 335 NFFLFFSIY 343
               + S+Y
Sbjct: 224 PSKHYISVY 232



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 92  PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKY-------LCMLYALFGIPLM 144
           P  F+    WSF    +F     ST+G+G     T   K+       L  ++ L G+  +
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247

Query: 145 FLVL 148
            L+L
Sbjct: 248 ALIL 251


>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
           [Homo sapiens]
          Length = 262

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 18  GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75
           G++ P    L   V Y L+GA +F  +E      + D  + EK  FLE    +    +  
Sbjct: 12  GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65

Query: 76  VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133
           +E   Q + +  ++ V P+  +   ++W F SS FF  TV +T+GYG + P T  G+  C
Sbjct: 66  MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125

Query: 134 MLYALFGIPLMFLVLTDTG 152
           + YAL GIPL  + L   G
Sbjct: 126 VFYALLGIPLNVIFLNHLG 144



 Score = 35.8 bits (81), Expect = 0.067
 Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 4/57 (7%)

Query: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVL 331
           QV  L + L +  L++  +     + +  W     F   FYF F+TL+TIGFGD V+
Sbjct: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVV 220


>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
           [Homo sapiens]
          Length = 322

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 18  GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75
           G++ P    L   V Y L+GA +F  +E      + D  + EK  FLE    +    +  
Sbjct: 12  GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65

Query: 76  VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133
           +E   Q + +  ++ V P+  +   ++W F SS FF  TV +T+GYG + P T  G+  C
Sbjct: 66  MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125

Query: 134 MLYALFGIPLMFLVLTDTG 152
           + YAL GIPL  + L   G
Sbjct: 126 VFYALLGIPLNVIFLNHLG 144



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 4/64 (6%)

Query: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHP 334
           QV  L + L +  L++  +     + +  W     F   FYF F+TL+TIGFGD V+ HP
Sbjct: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVVGHP 223

Query: 335 NFFL 338
             F+
Sbjct: 224 LNFI 227


>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
           [Homo sapiens]
          Length = 309

 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 18  GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75
           G++ P    L   V Y L+GA +F  +E      + D  + EK  FLE    +    +  
Sbjct: 12  GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65

Query: 76  VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133
           +E   Q + +  ++ V P+  +   ++W F SS FF  TV +T+GYG + P T  G+  C
Sbjct: 66  MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125

Query: 134 MLYALFGIPLMFLVLTDTG 152
           + YAL GIPL  + L   G
Sbjct: 126 VFYALLGIPLNVIFLNHLG 144



 Score = 36.6 bits (83), Expect = 0.039
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHP 334
           QV  L + L +  L++  +     + +  W     F   FYF F+TL+TIGFGD V+   
Sbjct: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVVGTD 223

Query: 335 NFFLFFSIY 343
               + S+Y
Sbjct: 224 PSKHYISVY 232



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 92  PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKY-------LCMLYALFGIPLM 144
           P  F+    WSF    +F     ST+G+G     T   K+       L  ++ L G+  +
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247

Query: 145 FLVL 148
            L+L
Sbjct: 248 ALIL 251


>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
          Length = 336

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 41/133 (30%), Positives = 67/133 (50%), Gaps = 12/133 (9%)

Query: 23  GLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQD 82
           G   L +L+ Y + GAVVFS++E     +  +D   ++  +   R L   E + E + + 
Sbjct: 24  GFLVLGYLL-YLVFGAVVFSSVE-----LPYEDLLRQELRKLKRRFLEEHECLSEQQLEQ 77

Query: 83  LQGHLQKVKPQWFNRTTH------WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLY 136
             G + +      +  ++      W F S+LFF  TV ST GYG+  P++  GK  C++Y
Sbjct: 78  FLGRVLEASNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIY 137

Query: 137 ALFGIPLMFLVLT 149
           ++ GIP   L LT
Sbjct: 138 SVIGIPFTLLFLT 150



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/47 (42%), Positives = 28/47 (59%), Gaps = 4/47 (8%)

Query: 288 LIVFAYISC----AAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
           L+ F  +SC     AA+    E   +F  +FYFCF++L+TIG GD V
Sbjct: 186 LLGFVTVSCFFFIPAAVFSVLEDDWNFLESFYFCFISLSTIGLGDYV 232



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 18/66 (27%), Positives = 32/66 (48%), Gaps = 1/66 (1%)

Query: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRL-IDIYK 367
           DF +A +F    L+T G+G TV        F  IY ++G+    +    V  R+ + + +
Sbjct: 103 DFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFLTAVVQRITVHVTR 162

Query: 368 NVMLFF 373
             +L+F
Sbjct: 163 RPVLYF 168



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 7/55 (12%)

Query: 101 WSFLSSLFFCCTVFSTVGY-------GYIYPVTRLGKYLCMLYALFGIPLMFLVL 148
           W+FL S +FC    ST+G        GY      L K     Y L G+  M +VL
Sbjct: 210 WNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264


>gi|15718767 TRAAK [Homo sapiens]
          Length = 393

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 4/140 (2%)

Query: 24  LCFLCFLVTYALVGAVVFSAIEDGQVLVAADD-GEF-EKFLEELCRILNCSETVVEDRKQ 81
           L  L  ++ Y + GA+VF A+E      A  + GE  EKFL     + +    ++     
Sbjct: 7   LALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEVA 66

Query: 82  DLQGHLQKVKPQWFNRTTH--WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALF 139
           D  G     +    + ++H  W   S+ FF  T+ +T+GYG +   T  G+  C+ YAL 
Sbjct: 67  DALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALV 126

Query: 140 GIPLMFLVLTDTGDILATIL 159
           GIPL  ++L   GD L + L
Sbjct: 127 GIPLFGILLAGVGDRLGSSL 146



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 19/54 (35%), Positives = 28/54 (51%)

Query: 309 DFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRL 362
           D  +AF+F    +TTIG+G+  L      LF   Y +VG+ +  I    V +RL
Sbjct: 89  DLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYALVGIPLFGILLAGVGDRL 142



 Score = 32.0 bits (71), Expect = 0.96
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 7/52 (13%)

Query: 285 IIALIVFAYISCAAAILP------FWETQLDFENAFYFCFVTLTTIGFGDTV 330
           +++ ++F  I C   +L       + E     E A YF  VTLTT+GFGD V
Sbjct: 169 VLSAMLFLLIGCLLFVLTPTFVFCYMEDWSKLE-AIYFVIVTLTTVGFGDYV 219


>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
          Length = 313

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 26/60 (43%), Positives = 38/60 (63%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
           W F S+LFF  T+ +TVGYGY  P+T  GK   + +AL G+P   L+LT +   L+ +L+
Sbjct: 91  WDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSLLLT 150



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 18/46 (39%), Positives = 26/46 (56%)

Query: 285 IIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
           ++ ++V       A I    E    F +AFYFCF++L+TIG GD V
Sbjct: 176 LLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYV 221



 Score = 35.8 bits (81), Expect = 0.067
 Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 7/55 (12%)

Query: 101 WSFLSSLFFCCTVFSTVGYG-YI------YPVTRLGKYLCMLYALFGIPLMFLVL 148
           WSFL + +FC    ST+G G Y+       P   L K L  +Y   G+  M LVL
Sbjct: 199 WSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLVL 253


>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
          Length = 499

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 6/126 (4%)

Query: 30  LVTYALVGAVVFSAIEDGQVLVAADDGEFEKF--LEEL-CRILNCSETVVEDRKQDLQGH 86
           ++ Y  +GA +F  +E+     A  +   +K   L+E  C      + ++E         
Sbjct: 12  IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71

Query: 87  LQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFL 146
           +     Q FN   +W++ +++ F  TV +T+GYG + P T  G+  C+ Y LFG+PL   
Sbjct: 72  VAITGNQTFN---NWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLT 128

Query: 147 VLTDTG 152
            ++  G
Sbjct: 129 WISALG 134



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/109 (19%), Positives = 48/109 (44%), Gaps = 8/109 (7%)

Query: 269 LDEVGQQVERLDIPLPIIALIVFAYISCAAAILPFWETQ-LDFENAFYFCFVTLTTIGFG 327
           L + G  + +  I   +I ++    +        F  T+  ++    Y+ F+T++TIGFG
Sbjct: 148 LTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVTEGWNYIEGLYYSFITISTIGFG 207

Query: 328 DTVL-------EHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIYKNV 369
           D V         H  +  F  ++I +G+  + +      +  ++++K +
Sbjct: 208 DFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFVNWKVSMFVEVHKAI 256


>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
           [Homo sapiens]
          Length = 271

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 20/55 (36%), Positives = 31/55 (56%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDIL 155
           W  + S FF  +  +T+GYG + P T   +  C+ +AL GIPL  +VL   G ++
Sbjct: 101 WELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLM 155



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 12/22 (54%), Positives = 17/22 (77%)

Query: 310 FENAFYFCFVTLTTIGFGDTVL 331
           +   FYF F+TL+T+GFGD V+
Sbjct: 208 YTEGFYFAFITLSTVGFGDYVI 229


>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
           [Homo sapiens]
          Length = 332

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 20/55 (36%), Positives = 31/55 (56%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDIL 155
           W  + S FF  +  +T+GYG + P T   +  C+ +AL GIPL  +VL   G ++
Sbjct: 101 WELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLNLVVLNRLGHLM 155



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 20/60 (33%), Positives = 36/60 (60%), Gaps = 7/60 (11%)

Query: 310 FENAFYFCFVTLTTIGFGDTVL------EHPNFFL-FFSIYIIVGMEIVFIAFKLVQNRL 362
           +   FYF F+TL+T+GFGD V+       +P ++    S++I+ GM  + +  KL+ ++L
Sbjct: 208 YTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWLALIIKLILSQL 267



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 7/64 (10%)

Query: 92  PQWFNRTTHWSFLSSLFFCCTVFSTVGYG-YIYPVTRLGKY------LCMLYALFGIPLM 144
           P  F+    WS+    +F     STVG+G Y+  +    +Y      +  L+ LFG+  +
Sbjct: 197 PLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAWL 256

Query: 145 FLVL 148
            L++
Sbjct: 257 ALII 260


>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
           sapiens]
          Length = 257

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
           W   S+L F  ++ +T GYG++ P++  GK  CM+YA  G+P    ++      L  +LS
Sbjct: 90  WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLS 149


>gi|16118231 potassium channel, subfamily K, member 7 isoform A
           [Homo sapiens]
          Length = 307

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
           W   S+L F  ++ +T GYG++ P++  GK  CM+YA  G+P    ++      L  +LS
Sbjct: 90  WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLS 149


>gi|16118235 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
           W   S+L F  ++ +T GYG++ P++  GK  CM+YA  G+P    ++      L  +LS
Sbjct: 90  WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLS 149


>gi|16118233 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 20/60 (33%), Positives = 33/60 (55%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILS 160
           W   S+L F  ++ +T GYG++ P++  GK  CM+YA  G+P    ++      L  +LS
Sbjct: 90  WDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPASLALVATLRHCLLPVLS 149


>gi|16306555 potassium channel, subfamily K, member 13 [Homo
           sapiens]
          Length = 408

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 37/140 (26%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 24  LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83
           L     +V Y L GA VFSA+E       A + + ++  EE     +    +  D  +  
Sbjct: 21  LLLAALIVLYLLGGAAVFSALE------LAHERQAKQRWEERLANFSRGHNLSRDELRGF 74

Query: 84  QGHLQKVKPQWF---NRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFG 140
             H ++         N    W F  + +F  TV ST+G+G   P T  GK   + Y L G
Sbjct: 75  LRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134

Query: 141 IPLMFLVLTDTGDILATILS 160
                L      + L TI++
Sbjct: 135 CSSTILFFNLFLERLITIIA 154



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 300 ILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQ 359
           + P W    DF  AFYF    ++TIGFG T        +F   Y +VG     + F L  
Sbjct: 91  VRPRW----DFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTILFFNLFL 146

Query: 360 NRLIDIYKNVM 370
            RLI I   +M
Sbjct: 147 ERLITIIAYIM 157



 Score = 38.1 bits (87), Expect = 0.013
 Identities = 37/164 (22%), Positives = 67/164 (40%), Gaps = 20/164 (12%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYI-------YPVTRLGKYLCMLYALFGIPLMFLVLTDTGD 153
           WS+  SL+FC   FST+G+G +       Y    L ++   ++ L G+  ++ +     +
Sbjct: 222 WSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLF----N 277

Query: 154 ILATILSTSYNRFRKFPFFTRPLLSKWCP---KSLFKKKPDPKPADEAVPQIIISAEELP 210
           +++ ++  S N      +  R + S  CP   + L + + +         +  IS E   
Sbjct: 278 VISILIKQSLN------WILRKMDSGCCPQCQRGLLRSRRNVVMPGSVRNRCNISIETDG 331

Query: 211 GPKLGTCPSRPSCSMELFERSHALEKQNTLQLPPQAMERSNSCP 254
             +  T   R S  M   +   A  K +   L  Q  E +N CP
Sbjct: 332 VAESDTDGRRLSGEMISMKDLLAANKASLAILQKQLSEMANGCP 375



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 7/72 (9%)

Query: 294 ISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV------LEHPNFFLFFS-IYIIV 346
           ISC A+ +        + ++ YFCFV  +TIGFGD V       E    + F + ++I++
Sbjct: 208 ISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGLYRFANFVFILM 267

Query: 347 GMEIVFIAFKLV 358
           G+  ++  F ++
Sbjct: 268 GVCCIYSLFNVI 279


>gi|11545761 potassium channel, subfamily K, member 12 [Homo
           sapiens]
          Length = 430

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 9/111 (8%)

Query: 33  YALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQGHLQKVKP 92
           Y + GA VFSA+E      +  + E         R  + +  V E   +    H +    
Sbjct: 49  YLVAGATVFSALE------SPGEAEARARWGATLRNFSAAHGVAEPELRAFLRHYEAALA 102

Query: 93  QWFNRTT---HWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFG 140
                      W F  + +F  TV ST+G+G   P T  GK   + Y LFG
Sbjct: 103 AGVRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFG 153



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 20/47 (42%), Positives = 30/47 (63%), Gaps = 1/47 (2%)

Query: 285 IIALIVFAYI-SCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTV 330
           ++ L +FA + SC A+ +       D+ ++ YFCFVT +TIGFGD V
Sbjct: 217 LLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLV 263



 Score = 36.6 bits (83), Expect = 0.039
 Identities = 18/57 (31%), Positives = 29/57 (50%), Gaps = 16/57 (28%)

Query: 101 WSFLSSLFFCCTVFSTVGYGYIYP----------VTRLGKYL------CMLYALFGI 141
           W ++ SL+FC   FST+G+G +            + RLG +L      C +Y+LF +
Sbjct: 241 WDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNV 297



 Score = 36.2 bits (82), Expect = 0.051
 Identities = 24/74 (32%), Positives = 32/74 (43%), Gaps = 4/74 (5%)

Query: 297 AAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFK 356
           A A+ P W    DF  AFYF    ++TIGFG T         F   Y + G     + F 
Sbjct: 107 ADALRPRW----DFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFN 162

Query: 357 LVQNRLIDIYKNVM 370
           L   R+I +   +M
Sbjct: 163 LFLERIISLLAFIM 176


>gi|19424136 potassium channel, subfamily V, member 2 [Homo sapiens]
          Length = 545

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 4/68 (5%)

Query: 106 SLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNR 165
           S ++     STVGYG +YP T LG++   L   FGI L  + ++    IL    S  Y++
Sbjct: 447 SWWWAAVSISTVGYGDMYPETHLGRFFAFLCIAFGIILNGMPIS----ILYNKFSDYYSK 502

Query: 166 FRKFPFFT 173
            + + + T
Sbjct: 503 LKAYEYTT 510


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 37.0 bits (84), Expect = 0.030
 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 15/131 (11%)

Query: 108 FFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFR 167
           ++     +T+GYG +YP T  G  +  L AL G      VLT     +A  +    N F 
Sbjct: 428 WWAVVTMTTLGYGDMYPKTWSGMLVGALCALAG------VLT-----IAMPVPVIVNNFG 476

Query: 168 KFPFFTRPLLSKWCPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMEL 227
            +  ++  +  +  PK   +KK  P+PA    P    S E  P     +  S P+    +
Sbjct: 477 MY--YSLAMAKQKLPKK--RKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGM 532

Query: 228 FERSHALEKQN 238
            ER  A  KQN
Sbjct: 533 IERKRADSKQN 543


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 37.0 bits (84), Expect = 0.030
 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 15/131 (11%)

Query: 108 FFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPLMFLVLTDTGDILATILSTSYNRFR 167
           ++     +T+GYG +YP T  G  +  L AL G      VLT     +A  +    N F 
Sbjct: 428 WWAVVTMTTLGYGDMYPKTWSGMLVGALCALAG------VLT-----IAMPVPVIVNNFG 476

Query: 168 KFPFFTRPLLSKWCPKSLFKKKPDPKPADEAVPQIIISAEELPGPKLGTCPSRPSCSMEL 227
            +  ++  +  +  PK   +KK  P+PA    P    S E  P     +  S P+    +
Sbjct: 477 MY--YSLAMAKQKLPKK--RKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGM 532

Query: 228 FERSHALEKQN 238
            ER  A  KQN
Sbjct: 533 IERKRADSKQN 543


>gi|41349443 potassium channel, subfamily T, member 2 [Homo sapiens]
          Length = 1135

 Score = 36.6 bits (83), Expect = 0.039
 Identities = 18/50 (36%), Positives = 29/50 (58%)

Query: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFK 356
           +L+  ++ YFC VT +T+GFGD   E  +  LF    I V + ++ I F+
Sbjct: 226 KLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFE 275



 Score = 32.3 bits (72), Expect = 0.74
 Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

Query: 102 SFLSSLFFCCTVFSTVGYGYIYPVT---RLGKYLCMLYALFGIPLMF 145
           +   SL+FC   FSTVG+G + P T   +L     +  AL  +P+ F
Sbjct: 228 NLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQF 274


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,750,695
Number of Sequences: 37866
Number of extensions: 685590
Number of successful extensions: 2650
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2430
Number of HSP's gapped (non-prelim): 226
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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