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Search of human proteins with 32171238
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
(511 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens] 1020 0.0
gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens] 403 e-112
gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens] 395 e-110
gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens] 378 e-105
gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens] 378 e-105
gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens] 234 1e-61
gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens] 58 2e-08
gi|144226234 metastasis suppressor 1 [Homo sapiens] 57 4e-08
gi|46195763 metastasis suppressor 1-like [Homo sapiens] 49 1e-05
gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo ... 49 1e-05
gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo ... 49 1e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 46 7e-05
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 45 1e-04
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 45 1e-04
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 45 2e-04
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 45 2e-04
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo... 45 2e-04
gi|19224660 protein kinase C and casein kinase substrate in neur... 44 3e-04
gi|187761324 shootin1 isoform a [Homo sapiens] 41 0.003
gi|50511340 shootin1 isoform b [Homo sapiens] 41 0.003
gi|208022687 GTPase regulator associated with the focal adhesion... 40 0.004
gi|7662108 Cdc42 guanine exchange factor 9 [Homo sapiens] 40 0.007
gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... 40 0.007
gi|166197690 neuronal guanine nucleotide exchange factor isoform... 39 0.011
gi|166197688 neuronal guanine nucleotide exchange factor isoform... 39 0.011
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 39 0.011
gi|166064036 PAK-interacting exchange factor beta isoform d [Hom... 39 0.015
gi|166064034 PAK-interacting exchange factor beta isoform c [Hom... 39 0.015
gi|22027528 PAK-interacting exchange factor beta isoform b [Homo... 39 0.015
gi|151301154 mucin 6, gastric [Homo sapiens] 39 0.015
>gi|32171238 BAI1-associated protein 2-like 1 [Homo sapiens]
Length = 511
Score = 1020 bits (2638), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGE 60
MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGE
Sbjct: 1 MSRGPEEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGE 60
Query: 61 IATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLK 120
IATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLK
Sbjct: 61 IATGSPVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLK 120
Query: 121 RYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIAD 180
RYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIAD
Sbjct: 121 RYQTEHKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIAD 180
Query: 181 GCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIM 240
GCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIM
Sbjct: 181 GCKEALLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIM 240
Query: 241 NMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDM 300
NMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDM
Sbjct: 241 NMIEEIKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDM 300
Query: 301 FNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLS 360
FNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLS
Sbjct: 301 FNNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLS 360
Query: 361 FAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRS 420
FAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRS
Sbjct: 361 FAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRS 420
Query: 421 ISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGT 480
ISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGT
Sbjct: 421 ISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGT 480
Query: 481 AKPPFLSGENPFATVKLRPTVTNDRSAPIIR 511
AKPPFLSGENPFATVKLRPTVTNDRSAPIIR
Sbjct: 481 AKPPFLSGENPFATVKLRPTVTNDRSAPIIR 511
>gi|222080100 BAI1-associated protein 2 isoform 4 [Homo sapiens]
Length = 534
Score = 403 bits (1035), Expect = e-112
Identities = 220/542 (40%), Positives = 326/542 (60%), Gaps = 52/542 (9%)
Query: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+ + A K Y+D + K+GE+A+ S
Sbjct: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
Query: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
S ELG VL +++ H+++ L+E K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
Query: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
++K ++L+K QAELKK+R+KSQGS+N KY KE++Y++ ++++Q E++ +++DG K A
Sbjct: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
Query: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
L EE+RRFCFLV+K C A + YH + ELL KLP WQ+ C D K+PE+ + ++++
Sbjct: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
Query: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271
+ + P + P+ P+ +P + R +
Sbjct: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
Query: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330
+DY + P + S S L D ++N S NS T+E+ +L RS
Sbjct: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
Query: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390
S+A GL + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
Query: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450
WFP SYT++L+ + ++ + + S +S ST NL + + IPPPDY GAA+
Sbjct: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
Query: 451 RRADSARTTSTFKAPASKP-ETAAPNDANGTAKPPFLS-GENPFATVKLRPTVTNDRSAP 508
RA A+T S FK +P A P + G S NPFA V+L+PTVTNDRSAP
Sbjct: 476 -RAFPAQTASGFK---QRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDRSAP 531
Query: 509 II 510
++
Sbjct: 532 LL 533
>gi|9257199 BAI1-associated protein 2 isoform 2 [Homo sapiens]
Length = 552
Score = 395 bits (1016), Expect = e-110
Identities = 217/537 (40%), Positives = 321/537 (59%), Gaps = 52/537 (9%)
Query: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+ + A K Y+D + K+GE+A+ S
Sbjct: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
Query: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
S ELG VL +++ H+++ L+E K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
Query: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
++K ++L+K QAELKK+R+KSQGS+N KY KE++Y++ ++++Q E++ +++DG K A
Sbjct: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
Query: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
L EE+RRFCFLV+K C A + YH + ELL KLP WQ+ C D K+PE+ + ++++
Sbjct: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
Query: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271
+ + P + P+ P+ +P + R +
Sbjct: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
Query: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330
+DY + P + S S L D ++N S NS T+E+ +L RS
Sbjct: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
Query: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390
S+A GL + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
Query: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450
WFP SYT++L+ + ++ + + S +S ST NL + + IPPPDY GAA+
Sbjct: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
Query: 451 RRADSARTTSTFKAPASKP-ETAAPNDANGTAKPPFLS-GENPFATVKLRPTVTNDR 505
RA A+T S FK +P A P + G S NPFA V+L+PTVTNDR
Sbjct: 476 -RAFPAQTASGFK---QRPYSVAVPAFSQGLDDYGARSMSRNPFAHVQLKPTVTNDR 528
>gi|5453565 BAI1-associated protein 2 isoform 3 [Homo sapiens]
Length = 520
Score = 378 bits (971), Expect = e-105
Identities = 199/493 (40%), Positives = 299/493 (60%), Gaps = 47/493 (9%)
Query: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+ + A K Y+D + K+GE+A+ S
Sbjct: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
Query: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
S ELG VL +++ H+++ L+E K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
Query: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
++K ++L+K QAELKK+R+KSQGS+N KY KE++Y++ ++++Q E++ +++DG K A
Sbjct: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
Query: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
L EE+RRFCFLV+K C A + YH + ELL KLP WQ+ C D K+PE+ + ++++
Sbjct: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
Query: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271
+ + P + P+ P+ +P + R +
Sbjct: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
Query: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330
+DY + P + S S L D ++N S NS T+E+ +L RS
Sbjct: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
Query: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390
S+A GL + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
Query: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450
WFP SYT++L+ + ++ + + S +S ST NL + + IPPPDY GAA+
Sbjct: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
Query: 451 RRADSARTTSTFK 463
RA A+T S FK
Sbjct: 476 -RAFPAQTASGFK 487
>gi|9257197 BAI1-associated protein 2 isoform 1 [Homo sapiens]
Length = 521
Score = 378 bits (971), Expect = e-105
Identities = 199/493 (40%), Positives = 299/493 (60%), Gaps = 47/493 (9%)
Query: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
EE++RLTE+ Y+ +MEQFNP LRN I +GKNYEKA+ + A K Y+D + K+GE+A+ S
Sbjct: 7 EEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASES 66
Query: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
S ELG VL +++ H+++ L+E K FH E++ +LE+K+ELD +Y++A LK+YQTE
Sbjct: 67 QGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTE 126
Query: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
++K ++L+K QAELKK+R+KSQGS+N KY KE++Y++ ++++Q E++ +++DG K A
Sbjct: 127 QRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTA 186
Query: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
L EE+RRFCFLV+K C A + YH + ELL KLP WQ+ C D K+PE+ + ++++
Sbjct: 187 LTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQ 246
Query: 246 IKT----------------------PASTPVSGTPQASPMIERSNVVR------------ 271
+ + P + P+ P+ +P + R +
Sbjct: 247 VASNGATLPSALSASKSNLVISDPIPGAKPLPVPPELAPFVGRMSAQESTPIMNGVTGPD 306
Query: 272 -KDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGTSEDPSLQRSV 330
+DY + P + S S L D ++N S NS T+E+ +L RS
Sbjct: 307 GEDYSPWADRKAAQPKSLSPPQSQSKLSDSYSN-TLPVRKSVTPKNSYATTENKTLPRSS 365
Query: 331 SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARG 390
S+A GL + +VK IF H AG N TLLSF +GD+ITLL+PE +DGW YGE + +K RG
Sbjct: 366 SMAAGLERNGRMRVKAIFSHAAGDNSTLLSFKEGDLITLLVPEARDGWHYGESEKTKMRG 425
Query: 391 WFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAAD 450
WFP SYT++L+ + ++ + + S +S ST NL + + IPPPDY GAA+
Sbjct: 426 WFPFSYTRVLDSDGSDRLHM---SLQQGKSSSTGNLLDKDDLAIPPPDY------GAAS- 475
Query: 451 RRADSARTTSTFK 463
RA A+T S FK
Sbjct: 476 -RAFPAQTASGFK 487
>gi|113205091 BAI1-associated protein 2-like 2 [Homo sapiens]
Length = 529
Score = 234 bits (597), Expect = 1e-61
Identities = 167/554 (30%), Positives = 266/554 (48%), Gaps = 78/554 (14%)
Query: 6 EEVNRLTESTYRNVMEQFNPGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGS 65
++ R T + Y+++MEQFNP L NL+ LG NY +A +A+ A + Y+ + KIGE A S
Sbjct: 6 DQFYRSTMAIYKSIMEQFNPALENLVYLGNNYLRAFHALSEAAEVYFSAIQKIGERALQS 65
Query: 66 PVSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTE 125
P S LG +L+++S T + LN L+ + FH ++ +EK +LD++++ + + Y+ E
Sbjct: 66 PTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGGLLQHMEKNTKLDMQFIKDSRQHYELE 125
Query: 126 HKNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEA 185
++++ +LEK +EL ++ RK + +K E+V +++Q F+++ + A
Sbjct: 126 YRHRAANLEKCMSELWRMERKRDKNVREMK---------ESVNRLHAQMQAFVSESQRAA 176
Query: 186 LLEEKRRFCFLVDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEE 245
LEEKRR+ FL +KH +N + ++ +L +++ W+E +A + P +
Sbjct: 177 ELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQS-EASRSPSR------- 228
Query: 246 IKTPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPL----IDMF 301
A +P P P + D MPP P G ++SP +
Sbjct: 229 ----AHSPGLLGPALGPPYPSGRLTPTCLD--------MPPRPLGE-FSSPRSRHGSGSY 275
Query: 302 NNPATAAPNSQRVNNSTGTSEDPSLQRSVSVATGLNMMKK-----------QKVKTIFPH 350
A P SQ + PS S + + ++V+ + H
Sbjct: 276 GTEPDARPASQLEPDRRSLPRTPSASSLYSGSAQSSRSNSFGERPGGGGGARRVRALVSH 335
Query: 351 TAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTV 410
+ G+N TLL F+ GDV+ +L+PE ++GWLYG+ + S A GWFP +Y K LEE +T
Sbjct: 336 SEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSASGWFPEAYVKALEEGPVNPMTP 395
Query: 411 PTP-------SP-TPVR--------------SISTVNLSENSSVVIPPPDYLECLSMGAA 448
TP SP TP+ S S +L + I P +Y + S
Sbjct: 396 VTPMTSMTSMSPMTPMNPGNELPSRSYPLRGSHSLDDLLDRPGNSIAPSEYWDGQSRSRT 455
Query: 449 ADRRADSARTTSTFKAPASK----PETAAPNDA----NGTAKPP---FLSGENPFATVKL 497
R A + + P+S+ TA D + PP F G NPFATVKL
Sbjct: 456 PSRVPSRAPSPAPPPLPSSRRSSMGSTAVATDVKKLMSSEQYPPQELFPRGTNPFATVKL 515
Query: 498 RPTVTNDRSAPIIR 511
RPT+TNDRSAP+IR
Sbjct: 516 RPTITNDRSAPLIR 529
>gi|41406080 growth arrest-specific 7 isoform c [Homo sapiens]
Length = 476
Score = 58.2 bits (139), Expect = 2e-08
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 25/159 (15%)
Query: 339 MKKQKVKTIFPHTAGSNKTLLSFAQGDVITLL-IPEEKDGWLYGEHDVSKARGWFPSSYT 397
M + +T++P + + L FA G++ITLL +P+ GW GE + RGWFP+SY
Sbjct: 1 MSGARCRTLYPFSGERHGQGLRFAAGELITLLQVPD--GGWWEGEKE-DGLRGWFPASYV 57
Query: 398 KLLEENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRR--ADS 455
+LLE+ P P P E S VI PP + LS RR ++
Sbjct: 58 QLLEK--------PGMVPPPP--------GEESQTVILPPGWQSYLS---PQGRRYYVNT 98
Query: 456 ARTTSTFKAPASKPETAAPNDANGTAKPPFLSGENPFAT 494
+T++ P+S P A ++ ++ PP ++G + T
Sbjct: 99 TTNETTWERPSSSPGIPASPGSHRSSLPPTVNGYHASGT 137
>gi|144226234 metastasis suppressor 1 [Homo sapiens]
Length = 755
Score = 57.0 bits (136), Expect = 4e-08
Identities = 57/290 (19%), Positives = 122/290 (42%), Gaps = 28/290 (9%)
Query: 25 PGLRNLINLGKNYEKAVNAMILAGKAYYDGVAKIGEIATGSPVST-ELGHVLIEISSTHK 83
P + IN + + ++A A+ D K+ ++AT + T E+G L + H+
Sbjct: 28 PVWEDFINKAGKLQSQLRTTVVAAAAFLDAFQKVADMATNTRGGTREIGSALTRMCMRHR 87
Query: 84 KLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKI 143
+ L + +I+ L++++E K N K + E+K + ++K ++ K+
Sbjct: 88 SIEAKLRQFSSALIDCLINPLQEQMEEWKKVANQLDKDHAKEYKKARQEIKKKSSDTLKL 147
Query: 144 RRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCF-------L 196
++K++ R ++ + ++ V + +++ ++AL+EE+ RFC +
Sbjct: 148 QKKAKKGRGDIQPQLDSA--LQDVNDKYLLLEETEKQAVRKALIEERGRFCTFISMLRPV 205
Query: 197 VDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIK--------- 247
+++ I + S +L + +D K+P +I ++K
Sbjct: 206 IEEEISMLGEITHLQTISEDL--------KSLTMDPHKLPSSSEQVILDLKGSDYSWSYQ 257
Query: 248 TPASTPVSGTPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPL 297
TP S+P + + S + N V D+ S S P+ R +S L
Sbjct: 258 TPPSSPSTTMSRKSSVCSSLNSVNSS-DSRSSGSHSHSPSSHYRYRSSNL 306
Score = 34.7 bits (78), Expect = 0.21
Identities = 40/143 (27%), Positives = 55/143 (38%), Gaps = 33/143 (23%)
Query: 372 PEEKDGWLYGEHDV-SKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSENS 430
PEE+ GEH S + G P T + + +V P P P SI
Sbjct: 637 PEER-----GEHSPESPSVGEGPQGVTSMPSSMWSGQASVNPPLPGPKPSI--------- 682
Query: 431 SVVIPPPDYLECLSMGAAADR-RADSARTTSTFKAPASKPETAAPNDANGTAKPPFLSGE 489
P ++ + + A D+ R + T S + P S P +P D GE
Sbjct: 683 -----PEEHRQAIPESEAEDQEREPPSATVSPGQIPESDPADLSPRDTP--------QGE 729
Query: 490 NPFAT----VKLRPTVTNDRSAP 508
+ VKL+ T TNDRSAP
Sbjct: 730 DMLNAIRRGVKLKKTTTNDRSAP 752
>gi|46195763 metastasis suppressor 1-like [Homo sapiens]
Length = 747
Score = 48.9 bits (115), Expect = 1e-05
Identities = 35/158 (22%), Positives = 74/158 (46%), Gaps = 8/158 (5%)
Query: 45 ILAGKAYYDGVAKIGEIATGSPVST-ELGHVLIEISSTHKKLNESLDENFKKFHKEIIHE 103
+LA A+ D K+ ++AT + +T ++G L + H+ + L + + +I+
Sbjct: 47 VLAAVAFLDAFQKVADMATNTRGATRDIGSALTRMCMRHRSIETKLRQFTNALLESLINP 106
Query: 104 LEKKIELDVKYMNATLKRYQTEHKNKLESLEKSQAELKKIRRKSQ----GSRNALKYEHK 159
L+++IE K N K + E+K ++K ++ K+++K++ G +
Sbjct: 107 LQERIEDWKKAANQLDKDHAKEYKRARHEIKKKSSDTLKLQKKARKELLGKGDLQPQLDS 166
Query: 160 EIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLV 197
++ V + E +K + AL+EE+ RFC +
Sbjct: 167 ALQDVNDMYLLLEETEK---QAVRRALIEERGRFCTFI 201
>gi|67514036 SH3-domain kinase binding protein 1 isoform b [Homo
sapiens]
Length = 628
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/157 (28%), Positives = 61/157 (38%), Gaps = 9/157 (5%)
Query: 341 KQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD-GWLYGEHDVSKARGWFPSSYTKL 399
K K IFP+ A N L+ +GD++TL+ + D GW GE ++ RG FP ++ KL
Sbjct: 232 KDYCKVIFPYEA-QNDDELTIKEGDIVTLINKDCIDVGWWEGE--LNGRRGVFPDNFVKL 288
Query: 400 LE---ENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSA 456
L E E P P PV + PP+ E L R +
Sbjct: 289 LPPDFEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPERE 348
Query: 457 RTTSTFK--APASKPETAAPNDANGTAKPPFLSGENP 491
K PA P+ P N ++P L P
Sbjct: 349 PKLDLQKPSVPAIPPKKPRPPKTNSLSRPGALPPRRP 385
>gi|13994242 SH3-domain kinase binding protein 1 isoform a [Homo
sapiens]
Length = 665
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/157 (28%), Positives = 61/157 (38%), Gaps = 9/157 (5%)
Query: 341 KQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD-GWLYGEHDVSKARGWFPSSYTKL 399
K K IFP+ A N L+ +GD++TL+ + D GW GE ++ RG FP ++ KL
Sbjct: 269 KDYCKVIFPYEA-QNDDELTIKEGDIVTLINKDCIDVGWWEGE--LNGRRGVFPDNFVKL 325
Query: 400 LE---ENETEAVTVPTPSPTPVRSISTVNLSENSSVVIPPPDYLECLSMGAAADRRADSA 456
L E E P P PV + PP+ E L R +
Sbjct: 326 LPPDFEKEGNRPKKPPPPSAPVIKQGAGTTERKHEIKKIPPERPEMLPNRTEEKERPERE 385
Query: 457 RTTSTFK--APASKPETAAPNDANGTAKPPFLSGENP 491
K PA P+ P N ++P L P
Sbjct: 386 PKLDLQKPSVPAIPPKKPRPPKTNSLSRPGALPPRRP 422
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 46.2 bits (108), Expect = 7e-05
Identities = 84/352 (23%), Positives = 149/352 (42%), Gaps = 50/352 (14%)
Query: 81 THKKLNESLDENFKKFHKEIIHELE-KKIELDVKYMNATLKRYQTEHKNKLESLEKSQAE 139
T KL+E ++F KE+ +++ L+ Y K + E K +LE ++K + E
Sbjct: 606 TASKLSEM--DSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERK-RLELMQKKKLE 662
Query: 140 LKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKRRFCFLVDK 199
+ R+ QG N K ++ E + ++ + Q+ I + +E EEK+R DK
Sbjct: 663 DEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQE--EERKAEEKQR----KDK 716
Query: 200 HCGFANH---------IHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPA 250
A ++Y L E N + D I+V EK +
Sbjct: 717 DTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSG--DIIQVDEKTVG--------E 766
Query: 251 STPVSGTPQASPMIERSNVVRK--DYDTLSKCSPK---MPPAPSGRAYTSPLIDMFNNPA 305
+ G+ Q + N V K + SPK +PP S A ++ + +N
Sbjct: 767 PGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQP 826
Query: 306 TAAPNSQRVNNS-----TGTSEDPSLQRSVSVATGL------NMMKKQKVKTIFPHTAGS 354
+ + Q V+ S T + + R+VS + +++ K + + TA
Sbjct: 827 ASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKK 886
Query: 355 NKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETE 406
+ L +F++ D+IT+L E+++ W +GE V RGWFP SY K++ +E +
Sbjct: 887 DNHL-NFSKHDIITVL--EQQENWWFGE--VHGGRGWFPKSYVKIIPGSEVK 933
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 345 KTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD----GWLYGEHDVSKARGWFPSSYTKLL 400
+ ++P A N +SF GD+I + +EK GWLYG + GWFP +Y + +
Sbjct: 736 RALYPFEA-RNHDEMSFNSGDIIQV---DEKTVGEPGWLYGSFQGNF--GWFPCNYVEKM 789
Query: 401 EENETEAVTVPTPSPTPVRSISTVNLSENSS 431
+E E P + P TV+LS S+
Sbjct: 790 PSSENEKAVSPKKALLP----PTVSLSATST 816
Score = 39.3 bits (90), Expect = 0.009
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 340 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDV---SKARGWFPSSY 396
KK ++ + S LS A G +I L++ + GW GE + +GWFP+S+
Sbjct: 1026 KKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQARGKKRQKGWFPASH 1084
Query: 397 TKLLEENETEAVTVPTPSPTPV 418
KLL + A TP+ PV
Sbjct: 1085 VKLLGPSSERA----TPAFHPV 1102
Score = 35.4 bits (80), Expect = 0.12
Identities = 15/53 (28%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 352 AGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENE 404
A +N+ LSF++G +I ++ ++ D W + +++ G FPS+Y K+ +++
Sbjct: 1112 AANNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTDSD 1161
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 45.4 bits (106), Expect = 1e-04
Identities = 72/305 (23%), Positives = 129/305 (42%), Gaps = 46/305 (15%)
Query: 127 KNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEAL 186
+ +LE ++K + E + R+ QG N K ++ E + ++ + Q+ I + +E
Sbjct: 677 RKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQE--EERK 734
Query: 187 LEEKRRFCFLVDKHCGFANH---------IHYYHLQSAELLNSKLPRWQETCVDAIKVPE 237
EEK+R DK A ++Y L E N + D I+V E
Sbjct: 735 AEEKQR----KDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSG--DIIQVDE 788
Query: 238 KIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRK--DYDTLSKCSPK---MPPAPSGRA 292
K + + G+ Q + N V K + SPK +PP S A
Sbjct: 789 KTVG--------EPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSA 840
Query: 293 YTSPLIDMFNNPATAAPNSQRVNNS-----TGTSEDPSLQRSVSVATGL------NMMKK 341
++ + +N + + Q V+ S T + + R+VS + +++
Sbjct: 841 TSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVEN 900
Query: 342 QKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLE 401
K + + TA + L +F++ D+IT+L E+++ W +GE V RGWFP SY K++
Sbjct: 901 LKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGE--VHGGRGWFPKSYVKIIP 955
Query: 402 ENETE 406
+E +
Sbjct: 956 GSEVK 960
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 345 KTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD----GWLYGEHDVSKARGWFPSSYTKLL 400
+ ++P A N +SF GD+I + +EK GWLYG + GWFP +Y + +
Sbjct: 763 RALYPFEA-RNHDEMSFNSGDIIQV---DEKTVGEPGWLYGSFQGNF--GWFPCNYVEKM 816
Query: 401 EENETEAVTVPTPSPTPVRSISTVNLSENSS 431
+E E P + P TV+LS S+
Sbjct: 817 PSSENEKAVSPKKALLP----PTVSLSATST 843
Score = 39.3 bits (90), Expect = 0.009
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 340 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDV---SKARGWFPSSY 396
KK ++ + S LS A G +I L++ + GW GE + +GWFP+S+
Sbjct: 1053 KKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQARGKKRQKGWFPASH 1111
Query: 397 TKLLEENETEAVTVPTPSPTPV 418
KLL + A TP+ PV
Sbjct: 1112 VKLLGPSSERA----TPAFHPV 1129
Score = 35.4 bits (80), Expect = 0.12
Identities = 15/53 (28%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 352 AGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENE 404
A +N+ LSF++G +I ++ ++ D W + +++ G FPS+Y K+ +++
Sbjct: 1139 AANNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTDSD 1188
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 45.4 bits (106), Expect = 1e-04
Identities = 72/305 (23%), Positives = 129/305 (42%), Gaps = 46/305 (15%)
Query: 127 KNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFIADGCKEAL 186
+ +LE ++K + E + R+ QG N K ++ E + ++ + Q+ I + +E
Sbjct: 677 RKRLELMQKKKLEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQE--EERK 734
Query: 187 LEEKRRFCFLVDKHCGFANH---------IHYYHLQSAELLNSKLPRWQETCVDAIKVPE 237
EEK+R DK A ++Y L E N + D I+V E
Sbjct: 735 AEEKQR----KDKDTLKAEEKKRETASVLVNYRALYPFEARNHDEMSFNSG--DIIQVDE 788
Query: 238 KIMNMIEEIKTPASTPVSGTPQASPMIERSNVVRK--DYDTLSKCSPK---MPPAPSGRA 292
K + + G+ Q + N V K + SPK +PP S A
Sbjct: 789 KTVG--------EPGWLYGSFQGNFGWFPCNYVEKMPSSENEKAVSPKKALLPPTVSLSA 840
Query: 293 YTSPLIDMFNNPATAAPNSQRVNNS-----TGTSEDPSLQRSVSVATGL------NMMKK 341
++ + +N + + Q V+ S T + + R+VS + +++
Sbjct: 841 TSTSSEPLSSNQPASVTDYQNVSFSNLTVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVEN 900
Query: 342 QKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLE 401
K + + TA + L +F++ D+IT+L E+++ W +GE V RGWFP SY K++
Sbjct: 901 LKAQALCSWTAKKDNHL-NFSKHDIITVL--EQQENWWFGE--VHGGRGWFPKSYVKIIP 955
Query: 402 ENETE 406
+E +
Sbjct: 956 GSEVK 960
Score = 39.3 bits (90), Expect = 0.009
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 345 KTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD----GWLYGEHDVSKARGWFPSSYTKLL 400
+ ++P A N +SF GD+I + +EK GWLYG + GWFP +Y + +
Sbjct: 763 RALYPFEA-RNHDEMSFNSGDIIQV---DEKTVGEPGWLYGSFQGNF--GWFPCNYVEKM 816
Query: 401 EENETEAVTVPTPSPTPVRSISTVNLSENSS 431
+E E P + P TV+LS S+
Sbjct: 817 PSSENEKAVSPKKALLP----PTVSLSATST 843
Score = 39.3 bits (90), Expect = 0.009
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 340 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDV---SKARGWFPSSY 396
KK ++ + S LS A G +I L++ + GW GE + +GWFP+S+
Sbjct: 1053 KKPEIAQVTSAYVASGSEQLSLAPGQLI-LILKKNTSGWWQGELQARGKKRQKGWFPASH 1111
Query: 397 TKLLEENETEAVTVPTPSPTPV 418
KLL + A TP+ PV
Sbjct: 1112 VKLLGPSSERA----TPAFHPV 1129
Score = 35.4 bits (80), Expect = 0.12
Identities = 15/53 (28%), Positives = 33/53 (62%), Gaps = 3/53 (5%)
Query: 352 AGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENE 404
A +N+ LSF++G +I ++ ++ D W + +++ G FPS+Y K+ +++
Sbjct: 1139 AANNEDELSFSKGQLINVMNKDDPDWW---QGEINGVTGLFPSNYVKMTTDSD 1188
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 15/110 (13%)
Query: 317 STGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD 376
+TG+S P L + V GL + + ++P A + L +F + DVIT+L E++D
Sbjct: 898 ATGSSPSPVLGQGEKVE-GL------QAQALYPWRAKKDNHL-NFNKNDVITVL--EQQD 947
Query: 377 GWLYGEHDVSKARGWFPSSYTKLLE---ENETEAVTVPTPSPTPVRSIST 423
W +GE V +GWFP SY KL+ T + + SP ++ +++
Sbjct: 948 MWWFGE--VQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVAS 995
Score = 37.0 bits (84), Expect = 0.043
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 4/88 (4%)
Query: 340 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKAR---GWFPSSY 396
KK ++ + + L+ A G +I L+ + GW GE + GWFP++Y
Sbjct: 1074 KKPEIAQVIASYTATGPEQLTLAPGQLI-LIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132
Query: 397 TKLLEENETEAVTVPTPSPTPVRSISTV 424
KLL ++ P T + ++ V
Sbjct: 1133 VKLLSPGTSKITPTEPPKSTALAAVCQV 1160
Score = 35.4 bits (80), Expect = 0.12
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 6/45 (13%)
Query: 377 GWLYGEHDVSKARGWFPSSYTKLLEENETEA----VTVPTPSPTP 417
GWL GE + GWFP++Y + + ENE A VT T +P P
Sbjct: 783 GWLGGE--LKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAP 825
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
Query: 347 IFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKL 399
++ +TA N L+F +G +I +L E+ D W + +V+ G FPS+Y KL
Sbjct: 1163 MYDYTA-QNDDELAFNKGQIINVLNKEDPDWW---KGEVNGQVGLFPSNYVKL 1211
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 15/110 (13%)
Query: 317 STGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKD 376
+TG+S P L + V GL + + ++P A + L +F + DVIT+L E++D
Sbjct: 898 ATGSSPSPVLGQGEKVE-GL------QAQALYPWRAKKDNHL-NFNKNDVITVL--EQQD 947
Query: 377 GWLYGEHDVSKARGWFPSSYTKLLE---ENETEAVTVPTPSPTPVRSIST 423
W +GE V +GWFP SY KL+ T + + SP ++ +++
Sbjct: 948 MWWFGE--VQGQKGWFPKSYVKLISGPIRKSTSMDSGSSESPASLKRVAS 995
Score = 37.0 bits (84), Expect = 0.043
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 4/88 (4%)
Query: 340 KKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKAR---GWFPSSY 396
KK ++ + + L+ A G +I L+ + GW GE + GWFP++Y
Sbjct: 1074 KKPEIAQVIASYTATGPEQLTLAPGQLI-LIRKKNPGGWWEGELQARGKKRQIGWFPANY 1132
Query: 397 TKLLEENETEAVTVPTPSPTPVRSISTV 424
KLL ++ P T + ++ V
Sbjct: 1133 VKLLSPGTSKITPTEPPKSTALAAVCQV 1160
Score = 35.4 bits (80), Expect = 0.12
Identities = 19/45 (42%), Positives = 25/45 (55%), Gaps = 6/45 (13%)
Query: 377 GWLYGEHDVSKARGWFPSSYTKLLEENETEA----VTVPTPSPTP 417
GWL GE + GWFP++Y + + ENE A VT T +P P
Sbjct: 783 GWLGGE--LKGKTGWFPANYAEKIPENEVPAPVKPVTDSTSAPAP 825
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
Query: 347 IFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKL 399
++ +TA N L+F +G +I +L E+ D W + +V+ G FPS+Y KL
Sbjct: 1163 MYDYTA-QNDDELAFNKGQIINVLNKEDPDWW---KGEVNGQVGLFPSNYVKL 1211
>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
sapiens]
Length = 805
Score = 44.7 bits (104), Expect = 2e-04
Identities = 34/120 (28%), Positives = 65/120 (54%), Gaps = 8/120 (6%)
Query: 78 ISSTHKKLNESLDENFKKFHKEIIHELEKKIEL-----DVKYMNATLKRYQTEHKNKLES 132
ISS KK + ++N +K + I LEK + DV+ + L+ + ++KN E+
Sbjct: 487 ISSLKKKCQKESEQNKEKQRR--IETLEKYLADLPTLDDVQSQSLQLQILEEKNKNLQEA 544
Query: 133 LEKSQAELKKIRRKSQGSRNAL-KYEHKEIEYVETVTSRQSEIQKFIADGCKEALLEEKR 191
L ++ +L++I+++ Q L + KE E V TV S Q ++++ + DG + +L+ K+
Sbjct: 545 LIDTEKKLEEIKKQCQDKETQLICQKKKEKELVTTVQSLQQKVERCLEDGIRLPMLDAKQ 604
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 43.9 bits (102), Expect = 3e-04
Identities = 72/323 (22%), Positives = 128/323 (39%), Gaps = 41/323 (12%)
Query: 86 NESLDENFKKFHKEIIHELEKKIELDVKYMNATLK---RYQTEHKNKLESLEKSQAELKK 142
+ + ++ F+K K + L K++E K +A K QT + SQ +L+K
Sbjct: 129 SRAAEDGFRKAQKPWLKRL-KEVEASKKSYHAARKDEKTAQTRESHAKADSAVSQEQLRK 187
Query: 143 IRRKSQGSRNALKYEHKEIEYVETV------TSRQSEIQKFIADGCKEALLEEKRRFCFL 196
++ + + R A + E + +Y +T+ T R E + + C+ A E++R F
Sbjct: 188 LQERVE--RCAKEAEKTKAQYEQTLAELHRYTPRYMEDMEQAFETCQAA---ERQRLLFF 242
Query: 197 VDKHCGFANHIHYYHLQSAELLNSKLPRWQETCVDAIKVPEKIMNMIEEIKTPASTPVSG 256
D H+ + L+ L + E D E+++ ST G
Sbjct: 243 KDMLLTLHQHLDLSSSEKFHELHRDLHQGIEAASDE-----------EDLRWWRSTHGPG 291
Query: 257 TPQASPMIERSNVVRKDYDTLSKCSPKMPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNN 316
P E ++ DT S K S T I + TA P +
Sbjct: 292 MAMNWPQFEEWSL-----DTQRTISRKEKGGRSPDEVTLTSI-VPTRDGTAPPPQSPGSP 345
Query: 317 STGTSEDPSLQRSV-SVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEK 375
TG E+ S + S ATG+ +V+ ++ + AG LSF G+ + + E++
Sbjct: 346 GTGQDEEWSDEESPRKAATGV------RVRALYDY-AGQEADELSFRAGEELLKMSEEDE 398
Query: 376 DGWLYGEHDVSKARGWFPSSYTK 398
GW G+ + G +P++Y +
Sbjct: 399 QGWCQGQLQSGRI-GLYPANYVE 420
>gi|187761324 shootin1 isoform a [Homo sapiens]
Length = 631
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 73 HVLIEISSTHKKLNESLDENFK---KFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNK 129
H+L++ S ++L ++LDEN K + +E I +K EL+ + N TL + K +
Sbjct: 250 HLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQ 309
Query: 130 LESLEKSQAELKKIRRKSQGSRNALKYEHKEIE 162
LE LE+ + EL+ + S+ LK+ E++
Sbjct: 310 LELLEEDKKELELKYQNSEEKARNLKHSVDELQ 342
>gi|50511340 shootin1 isoform b [Homo sapiens]
Length = 456
Score = 40.8 bits (94), Expect = 0.003
Identities = 28/93 (30%), Positives = 50/93 (53%), Gaps = 3/93 (3%)
Query: 73 HVLIEISSTHKKLNESLDENFK---KFHKEIIHELEKKIELDVKYMNATLKRYQTEHKNK 129
H+L++ S ++L ++LDEN K + +E I +K EL+ + N TL + K +
Sbjct: 250 HLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQ 309
Query: 130 LESLEKSQAELKKIRRKSQGSRNALKYEHKEIE 162
LE LE+ + EL+ + S+ LK+ E++
Sbjct: 310 LELLEEDKKELELKYQNSEEKARNLKHSVDELQ 342
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 40.4 bits (93), Expect = 0.004
Identities = 52/200 (26%), Positives = 82/200 (41%), Gaps = 32/200 (16%)
Query: 211 HLQSAELLNSKLPRWQE---TCVDAIKVPEK------IMNMIEEIKTPASTPVSGTPQAS 261
HL + +SK P E T ++ EK I+N +++ +S P S +S
Sbjct: 582 HLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIIN--SSLESVSSNPNSILNSSS 639
Query: 262 PMIERSNVVRKDYDTLSKCSPK-MPPAPSGRAYTSPLIDMFNNPATAAPNSQRVNNSTGT 320
+ N D + P +PP PS + SP MF+ P++ P S T
Sbjct: 640 SLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSAPSSPMPTS-------ST 692
Query: 321 SEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLY 380
S D S V+T +K K ++ A + + LSF G V + P ++ GWL
Sbjct: 693 SSDSS-----PVSTPF-----RKAKALYACKA-EHDSELSFTAGTVFDNVHPSQEPGWLE 741
Query: 381 GEHDVSKARGWFPSSYTKLL 400
G ++ G P +Y + L
Sbjct: 742 G--TLNGKTGLIPENYVEFL 759
>gi|7662108 Cdc42 guanine exchange factor 9 [Homo sapiens]
Length = 516
Score = 39.7 bits (91), Expect = 0.007
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 4/68 (5%)
Query: 345 KTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENE 404
+ ++ H +N+ L +F GDVI +L KD W +G+ D + GWFP+S+ +L E
Sbjct: 14 EAVWDHVTMANREL-AFKAGDVIKVLDASNKDWW-WGQIDDEE--GWFPASFVRLWVNQE 69
Query: 405 TEAVTVPT 412
E P+
Sbjct: 70 DEVEEGPS 77
>gi|22027525 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo
sapiens]
Length = 776
Score = 39.7 bits (91), Expect = 0.007
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 12/130 (9%)
Query: 307 AAPNSQRVNNSTGTSEDPS-LQR-SVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQG 364
+A N+ + N S S LQR S +V N + VK F + +N+ LS +G
Sbjct: 126 SAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGSHQLIVKARF-NFKQTNEDELSVCKG 184
Query: 365 DVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTV 424
D+I + EE W E ++ GWFPS+Y + ++ +E SP V+ T
Sbjct: 185 DIIYVTRVEEGGWW---EGTLNGRTGWFPSNYVREIKSSERPL------SPKAVKGFETA 235
Query: 425 NLSENSSVVI 434
L++N V+
Sbjct: 236 PLTKNYYTVV 245
>gi|166197690 neuronal guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 618
Score = 38.9 bits (89), Expect = 0.011
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 327 QRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVS 386
+R+ V+ ++ +V+ + P+ A L+ D++ +L + DGW++GE
Sbjct: 508 RRTKFVSFTSRLLDCPQVQCVHPYVA-QQPDELTLELADILNIL-DKTDDGWIFGERLHD 565
Query: 387 KARGWFPSSYTK 398
+ RGWFPSS T+
Sbjct: 566 QERGWFPSSMTE 577
>gi|166197688 neuronal guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 710
Score = 38.9 bits (89), Expect = 0.011
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 2/72 (2%)
Query: 327 QRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVS 386
+R+ V+ ++ +V+ + P+ A L+ D++ +L + DGW++GE
Sbjct: 600 RRTKFVSFTSRLLDCPQVQCVHPYVA-QQPDELTLELADILNIL-DKTDDGWIFGERLHD 657
Query: 387 KARGWFPSSYTK 398
+ RGWFPSS T+
Sbjct: 658 QERGWFPSSMTE 669
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 38.9 bits (89), Expect = 0.011
Identities = 33/112 (29%), Positives = 60/112 (53%), Gaps = 8/112 (7%)
Query: 67 VSTELGHVLIEISSTHKKLNESLDENFKKFHKEIIHELEKKIELDVKYMNATLKRYQTEH 126
+ T+L L +I + K+LN+ L + + +E +H E+K+ D+K A L + E
Sbjct: 528 LKTQLYAALQQIENLRKELNDVLTK--RALQEEELHSKEEKLR-DIKSHQADL---ELEV 581
Query: 127 KNKLESLEKSQAELKKIRRKSQGSRNALKYEHKEIEYVETVTSRQSEIQKFI 178
KN L+++ + ++ELKK + K Q S+ ++ H E E E S+ + K +
Sbjct: 582 KNSLDTIHRLESELKK-QSKIQ-SQMKVEKAHLEEEIAELKKSQAQDKAKLL 631
>gi|166064036 PAK-interacting exchange factor beta isoform d [Homo
sapiens]
Length = 753
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 328 RSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSK 387
RS+ + N + K F T N+ LSF++GDVI + EE W E ++
Sbjct: 125 RSLDMTDNSNNQLVVRAKFNFQQT---NEDELSFSKGDVIHVTRVEEGGWW---EGTLNG 178
Query: 388 ARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSEN 429
GWFPS+Y + ++ +E +P + T ++++
Sbjct: 179 RTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKS 220
>gi|166064034 PAK-interacting exchange factor beta isoform c [Homo
sapiens]
Length = 803
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 328 RSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSK 387
RS+ + N + K F T N+ LSF++GDVI + EE W E ++
Sbjct: 175 RSLDMTDNSNNQLVVRAKFNFQQT---NEDELSFSKGDVIHVTRVEEGGWW---EGTLNG 228
Query: 388 ARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSEN 429
GWFPS+Y + ++ +E +P + T ++++
Sbjct: 229 RTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKS 270
>gi|22027528 PAK-interacting exchange factor beta isoform b [Homo
sapiens]
Length = 782
Score = 38.5 bits (88), Expect = 0.015
Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 6/102 (5%)
Query: 328 RSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSFAQGDVITLLIPEEKDGWLYGEHDVSK 387
RS+ + N + K F T N+ LSF++GDVI + EE W E ++
Sbjct: 154 RSLDMTDNSNNQLVVRAKFNFQQT---NEDELSFSKGDVIHVTRVEEGGWW---EGTLNG 207
Query: 388 ARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSISTVNLSEN 429
GWFPS+Y + ++ +E +P + T ++++
Sbjct: 208 RTGWFPSNYVREVKASEKPVSPKSGTLKSPPKGFDTTAINKS 249
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 38.5 bits (88), Expect = 0.015
Identities = 56/244 (22%), Positives = 88/244 (36%), Gaps = 35/244 (14%)
Query: 248 TPASTPVSGTPQAS--PMIERSNVVRKDYDTLSKCSPKMPP--APSGRAYTSPLIDMFNN 303
T S P +G+P S P+ S Y T S +P P + +P
Sbjct: 1405 TTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTSLVTPSTHTVIT 1464
Query: 304 PATAAPNSQRVNNS--TGTSEDPSLQRSVSVATGLNMMKKQKVKTIFPHTAGSNKTLLSF 361
P A + N+S TGT P+ + ATG I P T+G+++ SF
Sbjct: 1465 PTHAQMATSASNHSAPTGTIPPPTTLK----ATG----STHTAPPITPTTSGTSQAHSSF 1516
Query: 362 AQGDVITLLIPEEKDGWLYGEHDVSKARGWFPSSYTKLLEENETEAVTVPTPSPTPVRSI 421
+ T L +S T E T T+ TP+PT R+
Sbjct: 1517 STNKTPTSLHSH--------------------TSSTHHPEVTPTSTTTI-TPNPTSTRTR 1555
Query: 422 STVNLSENSSVVIPPPDYLECLSMGAAADRRADSARTTSTFKAPASKPETAAPNDANGTA 481
+ V + +++ PPP + ++ + T ++FK + P + P T
Sbjct: 1556 TPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTH 1615
Query: 482 KPPF 485
PPF
Sbjct: 1616 VPPF 1619
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.362
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,211,933
Number of Sequences: 37866
Number of extensions: 977892
Number of successful extensions: 4577
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 303
Number of HSP's that attempted gapping in prelim test: 4048
Number of HSP's gapped (non-prelim): 844
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.