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Search of human proteins with 32171215
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32171215 CREB regulated transcription coactivator 2 [Homo
sapiens]
(693 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32171215 CREB regulated transcription coactivator 2 [Homo sap... 1411 0.0
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [... 348 1e-95
gi|110431354 transducer of regulated CREB protein 3 isoform a [H... 340 2e-93
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [... 338 8e-93
gi|110431352 transducer of regulated CREB protein 3 isoform b [H... 337 3e-92
gi|55750053 atrophin-1 [Homo sapiens] 81 3e-15
gi|55750041 atrophin-1 [Homo sapiens] 81 3e-15
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 72 2e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 69 2e-11
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 67 7e-11
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 2e-09
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 62 2e-09
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 62 2e-09
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 62 2e-09
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 62 2e-09
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 60 7e-09
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 59 1e-08
gi|38373671 SEC24-related protein C [Homo sapiens] 59 2e-08
gi|38373669 SEC24-related protein C [Homo sapiens] 59 2e-08
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 58 3e-08
gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens] 58 3e-08
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 58 3e-08
gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens] 57 6e-08
gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens] 57 6e-08
gi|40807452 peroxisome proliferator-activated receptor gamma, co... 56 1e-07
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 55 2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 55 2e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 55 2e-07
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 55 2e-07
gi|163965366 nascent polypeptide-associated complex alpha subuni... 55 2e-07
>gi|32171215 CREB regulated transcription coactivator 2 [Homo
sapiens]
Length = 693
Score = 1411 bits (3652), Expect = 0.0
Identities = 693/693 (100%), Positives = 693/693 (100%)
Query: 1 MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA 60
MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA
Sbjct: 1 MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA 60
Query: 61 YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR 120
YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR
Sbjct: 61 YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRR 120
Query: 121 YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVM 180
YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVM
Sbjct: 121 YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVM 180
Query: 181 NPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSS 240
NPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSS
Sbjct: 181 NPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSS 240
Query: 241 RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS 300
RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS
Sbjct: 241 RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS 300
Query: 301 LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ 360
LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ
Sbjct: 301 LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ 360
Query: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST 420
PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST
Sbjct: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST 420
Query: 421 PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD 480
PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD
Sbjct: 421 PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD 480
Query: 481 QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS 540
QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS
Sbjct: 481 QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS 540
Query: 541 GHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTF 600
GHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTF
Sbjct: 541 GHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTF 600
Query: 601 NHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRM 660
NHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRM
Sbjct: 601 NHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRM 660
Query: 661 EPLGLEGLNMLSDPCALLPDPAVEESFRSDRLQ 693
EPLGLEGLNMLSDPCALLPDPAVEESFRSDRLQ
Sbjct: 661 EPLGLEGLNMLSDPCALLPDPAVEESFRSDRLQ 693
>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
[Homo sapiens]
Length = 634
Score = 348 bits (892), Expect = 1e-95
Identities = 279/708 (39%), Positives = 361/708 (50%), Gaps = 104/708 (14%)
Query: 14 ASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR---LQAQK---LRLAYTRSSHY 67
A+++NPRKFSEKIAL Q+QAEETAAFEEVM D+ TR LQ QK L+L +R +Y
Sbjct: 2 ATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYY 61
Query: 68 GGSLPNVNQIGSGLAE--FQSPLHSP-LDSSRSTRHHGLVERVQRDPRRMVSPLRR---- 120
GGSLPNVNQIGSG + FQ+P S LD+SR+TRHHGLV+RV R+ R+ SP RR
Sbjct: 62 GGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLSV 121
Query: 121 --YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTS 178
+ R DS PY YLSPP ++SWRRT +SDSALH S
Sbjct: 122 DKHGRQADSCPYGTMYLSPPADTSWRRT-----------------------NSDSALHQS 158
Query: 179 VMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLD-DKHLLKP-WDAKKLS 236
M P+ +++ + + +R +L VP +EE + DK+L K WD KK
Sbjct: 159 TMTPTQPESFSSGSQD--VHQKRVLLLT------VPGMEETTSEADKNLSKQAWDTKK-- 208
Query: 237 SSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEET 296
+ SRP+SCEVPGINIFPS DQ ++P NTGGSLPDLTN+HFP PLPTPLDPEE
Sbjct: 209 -TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPDLTNIHFPSPLPTPLDPEEP 267
Query: 297 AYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASL 356
+P+LS +ST NL +THLGI G G G PG SP P+ S L SL
Sbjct: 268 TFPALSSSSSTGNLAANLTHLGIG---GAGQGMSTPG-SSPQHRPAGVSPL-------SL 316
Query: 357 SSPQPQLQGSHSHPSL-PASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPS 415
S+ + Q S P+L P S + + V L + + S P P
Sbjct: 317 STEARRQQAS---PTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPPPP 373
Query: 416 YPAS--TPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFS-PTMSPTLSSITQGVPL 472
PAS P P V L P L A R Q P + P+ P G P
Sbjct: 374 PPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSSLPQSPPENPGQPS 433
Query: 473 DTSKLSTDQRLPPYPYS--SPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSH 530
+++ L Y S SP+ PT P + + S G P S
Sbjct: 434 MGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF--------------SPGSSPQHTST 479
Query: 531 YGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFS-MESPSASLVLDPPGFS---EGPGFLG 586
G+ + G + + QQ R + + LEQF+ ME+ +S L PG + +G
Sbjct: 480 LGSVF--GDAYYEQQMAARQANALS-HQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMG 536
Query: 587 GEGPMGGPQDPHTFNHQNLTHCSRHGSGPNIIL--TGDSSPGFSKEIAAALAGVPGFEVS 644
G G D Q L + S H PNIIL TG+S P SKE+ ++LAGV
Sbjct: 537 LTGSHGSLPD-----SQQLGYAS-HSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFD 590
Query: 645 AAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692
+ + L DEL+++PL L+GL+ML+DP +L DPA E++FR DRL
Sbjct: 591 SDS-QFPL---DELKIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL 634
>gi|110431354 transducer of regulated CREB protein 3 isoform a [Homo
sapiens]
Length = 619
Score = 340 bits (873), Expect = 2e-93
Identities = 271/710 (38%), Positives = 353/710 (49%), Gaps = 115/710 (16%)
Query: 6 ANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSS 65
A PGS +A NPRKFSEKIAL QRQAEET AFE++M D+ +R+Q QKL+ +
Sbjct: 2 AASPGSGSA---NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQ-QLRLTQ 57
Query: 66 HYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT--- 122
++GGSLPNV+Q+ S +EFQ H D+ R TRHHGLVER R+ PL R +
Sbjct: 58 YHGGSLPNVSQLRSSASEFQPSFHQA-DNVRGTRHHGLVERPSRN---RFHPLHRRSGDK 113
Query: 123 --RHIDSSPYSPAYLSPPPESSW-RRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV 179
R D S + Y S P + SW R+ W + EK FRL SALNRT+SDSALHTS
Sbjct: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKD---EKHPGFRLTSALNRTNSDSALHTSA 170
Query: 180 MNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV-------PAIEENLLD-DKHLLKP-W 230
++ PQD Y G S P+ G DGE + P EENLL+ K L K W
Sbjct: 171 LSTKPQDPYGGGGQ-SAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLW 229
Query: 231 DAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP 290
+ K++ S S RPRSC+V G N FP Q + +NTGGSLPDLTNLH+ PLP
Sbjct: 230 ETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPAS 289
Query: 291 LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP 350
LD + + S+S GNS +N+ MTHLGI + GL S S+PS+Q++L+
Sbjct: 290 LDTTDHHFGSMSVGNSVNNIPAAMTHLGIR---------SSSGLQSSRSNPSIQATLNKT 340
Query: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410
L +SL+ +H S+P +S L SL +PSLS LS S
Sbjct: 341 VLSSSLN--------NHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPS--------- 383
Query: 411 LGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGV 470
R+ P+SPL+L GP + Q +Q S T +Q V
Sbjct: 384 ---------------RRRQPPVSPLTLSPGP----EAHQGFSRQLSSTSPLAPYPTSQMV 424
Query: 471 PLDTSKLS------TDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524
D S+LS Q PP PY +P Q T LQQP P
Sbjct: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAP------QELTQPLLQQPRAPE------------ 466
Query: 525 PGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGF 584
P+ Q + P SDF L + S+ + + D GP F
Sbjct: 467 -------------APAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAF 513
Query: 585 LGGEGPM--GGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFE 642
+ P+ G ++ H + S GS PN IL DSS K++ +ALAG+P E
Sbjct: 514 -PQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILPEDSSTSLFKDLNSALAGLP--E 570
Query: 643 VSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692
VS ++ LE+EL++EPL L+GLNMLSD L DP+VEE+FR+DRL
Sbjct: 571 VS-LNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 619
>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
[Homo sapiens]
Length = 650
Score = 338 bits (868), Expect = 8e-93
Identities = 280/727 (38%), Positives = 360/727 (49%), Gaps = 126/727 (17%)
Query: 14 ASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTR---LQAQK---LRLAYTRSSHY 67
A+++NPRKFSEKIAL Q+QAEETAAFEEVM D+ TR LQ QK L+L +R +Y
Sbjct: 2 ATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQYY 61
Query: 68 GGSLPNVNQIGSG----------------------LAEFQSPLHSPLDSSRSTRHHGLVE 105
GGSLPNVNQIGSG L FQS S LD+SR+TRHHGLV+
Sbjct: 62 GGSLPNVNQIGSGTMDLPFQPSGFLGEALAAAPVSLTPFQS---SGLDTSRTTRHHGLVD 118
Query: 106 RVQRDPRRMVSPLRR------YTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQL 159
RV R+ R+ SP RR + R DS PY YLSPP ++SWRRT
Sbjct: 119 RVYRERGRLGSPHRRPLSVDKHGRQADSCPYGTMYLSPPADTSWRRT------------- 165
Query: 160 FRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEEN 219
+SDSALH S M P+ +++ + + +R +L VP +EE
Sbjct: 166 ----------NSDSALHQSTMTPTQPESFSSGSQD--VHQKRVLLLT------VPGMEET 207
Query: 220 LLD-DKHLLKP-WDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPD 277
+ DK+L K WD KK + SRP+SCEVPGINIFPS DQ ++P NTGGSLPD
Sbjct: 208 TSEADKNLSKQAWDTKK---TGSRPKSCEVPGINIFPSADQENTTALIPATHNTGGSLPD 264
Query: 278 LTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSP 337
LTN+HFP PLPTPLDPEE +P+LS +ST NL +THLGI G G G PG SP
Sbjct: 265 LTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIG---GAGQGMSTPG-SSP 320
Query: 338 LSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSL-PASSLARHVLPTTSLGHPSLSAPA 396
P+ S L SLS+ + Q S P+L P S + + V L
Sbjct: 321 QHRPAGVSPL-------SLSTEARRQQAS---PTLSPLSPITQAVAMDALSLEQQLPYAF 370
Query: 397 LSSSSSSSSTSSPVLGAPSYPAS--TPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQ 454
+ + S P P PAS P P V L P L A R Q P
Sbjct: 371 FTQAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLA 430
Query: 455 FS-PTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYS--SPSLVLPTQPHTPKSLQQPGLP 511
+ P+ P G P +++ L Y S SP+ PT P + +
Sbjct: 431 VTVPSSLPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGF------ 484
Query: 512 SQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFS-MESPSAS 570
S G P S G+ + G + + QQ R + + LEQF+ ME+ +S
Sbjct: 485 --------SPGSSPQHTSTLGSVF--GDAYYEQQMAARQANALS-HQLEQFNMMENAISS 533
Query: 571 LVLDPPGFS---EGPGFLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGPNIIL--TGDSSP 625
L PG + +G G G D Q L + S H PNIIL TG+S P
Sbjct: 534 SSLYSPGSTLNYSQAAMMGLTGSHGSLPD-----SQQLGYAS-HSGIPNIILTVTGESPP 587
Query: 626 GFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEE 685
SKE+ ++LAGV + + L DEL+++PL L+GL+ML+DP +L DPA E+
Sbjct: 588 SLSKELTSSLAGVGDVSFDSDS-QFPL---DELKIDPLTLDGLHMLNDPDMVLADPATED 643
Query: 686 SFRSDRL 692
+FR DRL
Sbjct: 644 TFRMDRL 650
>gi|110431352 transducer of regulated CREB protein 3 isoform b [Homo
sapiens]
Length = 618
Score = 337 bits (863), Expect = 3e-92
Identities = 271/710 (38%), Positives = 353/710 (49%), Gaps = 116/710 (16%)
Query: 6 ANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSS 65
A PGS +A NPRKFSEKIAL QRQAEET AFE++M D+ +R+Q QKL+ +
Sbjct: 2 AASPGSGSA---NPRKFSEKIALHTQRQAEETRAFEQLMTDLTLSRVQFQKLQ-QLRLTQ 57
Query: 66 HYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT--- 122
++GGSLPNV+Q+ S +EFQ H D+ R TRHHGLVER R+ PL R +
Sbjct: 58 YHGGSLPNVSQLRSSASEFQPSFHQA-DNVRGTRHHGLVERPSRN---RFHPLHRRSGDK 113
Query: 123 --RHIDSSPYSPAYLSPPPESSW-RRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV 179
R D S + Y S P + SW R+ W + EK FRL SALNRT+SDSALHTS
Sbjct: 114 PGRQFDGSAFGANYSSQPLDESWPRQQPPWKD---EKHPGFRLTSALNRTNSDSALHTSA 170
Query: 180 MNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV-------PAIEENLLD-DKHLLKP-W 230
++ PQD Y G S P+ G DGE + P EENLL+ K L K W
Sbjct: 171 LSTKPQDPYGGGGQ-SAWPAPYMGFCDGENNGHGEVASFPGPLKEENLLNVPKPLPKQLW 229
Query: 231 DAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP 290
+ K++ S S RPRSC+V G N FP Q + +NTGGSLPDLTNLH+ PLP
Sbjct: 230 ETKEIQSLSGRPRSCDVGGGNAFPHNGQNLGLSPFLGTLNTGGSLPDLTNLHYSTPLPAS 289
Query: 291 LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP 350
LD + + S+S GNS +N+ MTHLGI + GL S S+PS+Q++L+
Sbjct: 290 LDTTDHHFGSMSVGNSVNNIPAAMTHLGIR---------SSSGLQSSRSNPSIQATLNKT 340
Query: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410
L +SL+ +H S+P +S L SL +PSLS LS S
Sbjct: 341 VLSSSLN--------NHPQTSVPNASALHPSLRLFSLSNPSLSTTNLSGPS--------- 383
Query: 411 LGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGV 470
R+ P+SPL+L GP + Q +Q S T +Q V
Sbjct: 384 ---------------RRRQPPVSPLTLSPGP----EAHQGFSRQLSSTSPLAPYPTSQMV 424
Query: 471 PLDTSKLS------TDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524
D S+LS Q PP PY +P Q T LQQP P
Sbjct: 425 SSDRSQLSFLPTEAQAQVSPPPPYPAP------QELTQPLLQQPRAPE------------ 466
Query: 525 PGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGF 584
P+ Q + P SDF L + S+ + + D GP F
Sbjct: 467 -------------APAQQPQAASSLPQSDFQLLPAQGSSLTNFFPDVGFDQQSMRPGPAF 513
Query: 585 LGGEGPM--GGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFE 642
+ P+ G ++ H + S GS PN IL DSS K++ +ALAG+P E
Sbjct: 514 -PQQVPLVQQGSRELQDSFHLRPSPYSNCGSLPNTILP-DSSTSLFKDLNSALAGLP--E 569
Query: 643 VSAAGLELGLGLEDELRMEPLGLEGLNMLSDPCALLPDPAVEESFRSDRL 692
VS ++ LE+EL++EPL L+GLNMLSD L DP+VEE+FR+DRL
Sbjct: 570 VS-LNVDTPFPLEEELQIEPLSLDGLNMLSDSSMGLLDPSVEETFRADRL 618
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 81.3 bits (199), Expect = 3e-15
Identities = 158/644 (24%), Positives = 227/644 (35%), Gaps = 115/644 (17%)
Query: 1 MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA 60
+ + G PG + S+S+ + +K RQ + A EE + ++ Q
Sbjct: 27 LRSRGRASPGGVSTSSSDGKA-------EKSRQTAKKARVEEA----STPKVNKQGRSEE 75
Query: 61 YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDS--SRSTRHHGLVERVQRDPR------ 112
+ S + P + L QSP S LDS RS G DPR
Sbjct: 76 ISESESEETNAPKKTKTEQELPRPQSP--SDLDSLDGRSLNDDG-----SSDPRDIDQDN 128
Query: 113 RMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSAL---NRT 169
R SP +++ S + LS P + + P R P A + +
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPS 188
Query: 170 SSDSALHTSVMNPSPQ--DTYPGPTPP--SILPSRRGGILDGE-MDPKVPAIEENL---L 221
+ + H + P+ + PG PP + P GG+L G M PK ++
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 222 DDKHLLKPWDAKKLSSSSS------RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSL 275
K P +SSS + +P + V G N+ PS PAN P + P +L
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL-PSAPPPANFPHVTP------NL 301
Query: 276 PDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLH 335
P PPP PL+ + P L HL MG G G PG
Sbjct: 302 P-------PPPALRPLNNASASPPGLGAQPLPG-------HLPSPHAMGQGMGGLPPG-- 345
Query: 336 SPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAP 395
P P+L S + AS S+P P ++ +S S S SA
Sbjct: 346 -PEKGPTLAPS-PHSLPPASSSAPAPPMRFPYSSSS-------------------SSSAA 384
Query: 396 ALSSSSSSSSTSSPVLGA---PSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLP 452
A SSSSSSSS++SP + PSYP S P P SL + +Q LP
Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPHSFP-----------PPTSLSVSNQPPKYTQPSLP 433
Query: 453 KQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPS 512
Q + P P +L + P P+ PS + H P S
Sbjct: 434 SQAVWSQGPP-------PPPPYGRLLANSNAHPGPFP-PSTGAQSTAHPPVSTHHHHHQQ 485
Query: 513 QSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLV 572
Q Q Q +Q H+G PP P ++ P+ + + ++M SL
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPG-----AFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 573 LDPPGFSE-GPGFLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGP 615
PPG + P GP P + N + + GS P
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584
Score = 37.0 bits (84), Expect = 0.061
Identities = 86/403 (21%), Positives = 131/403 (32%), Gaps = 87/403 (21%)
Query: 85 QSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHIDSSPYSPAYLSPPPESSWR 144
QS H P+ ST HH ++ Q+ ++ ++ H +S P PPP +
Sbjct: 469 QSTAHPPV----STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP-------PPPGA--- 514
Query: 145 RTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGI 204
P L SS A H M+PS P P P+ LP +
Sbjct: 515 -----------------FPHPLEGGSSHHA-HPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556
Query: 205 LDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQ-PANVP 263
+ P P + + + SS+S C PSP Q P P
Sbjct: 557 SYSQAGPNGPPVSSS------------SNSSSSTSQGSYPCS------HPSPSQGPQGAP 598
Query: 264 VLPPAMNTGGSLPDLTNLHFP-PPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRG 322
+P PP+PT T ST T + G
Sbjct: 599 -------------------YPFPPVPTVTTSSATL--------STVIATVASSPAGYKTA 631
Query: 323 MGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPAS------S 376
GP SP ++ + P S + P S P+ P + +
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 377 LARHVLPTTS-LGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPL 435
+ LP G PSL P + +S +++ + P+ TP + R P P
Sbjct: 692 VGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Query: 436 SLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLS 478
++ P+ A +S + K + S VPL+ SKL+
Sbjct: 752 KVVDVPSHASQS-ARFNKHLDRGFNSCARSDLYFVPLEGSKLA 793
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 81.3 bits (199), Expect = 3e-15
Identities = 158/644 (24%), Positives = 227/644 (35%), Gaps = 115/644 (17%)
Query: 1 MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLA 60
+ + G PG + S+S+ + +K RQ + A EE + ++ Q
Sbjct: 27 LRSRGRASPGGVSTSSSDGKA-------EKSRQTAKKARVEEA----STPKVNKQGRSEE 75
Query: 61 YTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDS--SRSTRHHGLVERVQRDPR------ 112
+ S + P + L QSP S LDS RS G DPR
Sbjct: 76 ISESESEETNAPKKTKTEQELPRPQSP--SDLDSLDGRSLNDDG-----SSDPRDIDQDN 128
Query: 113 RMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSAL---NRT 169
R SP +++ S + LS P + + P R P A + +
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPS 188
Query: 170 SSDSALHTSVMNPSPQ--DTYPGPTPP--SILPSRRGGILDGE-MDPKVPAIEENL---L 221
+ + H + P+ + PG PP + P GG+L G M PK ++
Sbjct: 189 VTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPN 248
Query: 222 DDKHLLKPWDAKKLSSSSS------RPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSL 275
K P +SSS + +P + V G N+ PS PAN P + P +L
Sbjct: 249 GGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNL-PSAPPPANFPHVTP------NL 301
Query: 276 PDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLH 335
P PPP PL+ + P L HL MG G G PG
Sbjct: 302 P-------PPPALRPLNNASASPPGLGAQPLPG-------HLPSPHAMGQGMGGLPPG-- 345
Query: 336 SPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAP 395
P P+L S + AS S+P P ++ +S S S SA
Sbjct: 346 -PEKGPTLAPS-PHSLPPASSSAPAPPMRFPYSSSS-------------------SSSAA 384
Query: 396 ALSSSSSSSSTSSPVLGA---PSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLP 452
A SSSSSSSS++SP + PSYP S P P SL + +Q LP
Sbjct: 385 ASSSSSSSSSSASPFPASQALPSYPHSFP-----------PPTSLSVSNQPPKYTQPSLP 433
Query: 453 KQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPS 512
Q + P P +L + P P+ PS + H P S
Sbjct: 434 SQAVWSQGPP-------PPPPYGRLLANSNAHPGPFP-PSTGAQSTAHPPVSTHHHHHQQ 485
Query: 513 QSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLV 572
Q Q Q +Q H+G PP P ++ P+ + + ++M SL
Sbjct: 486 QQQQQQQQQQQQQQQQQHHGNSGPPPPG-----AFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 573 LDPPGFSE-GPGFLGGEGPMGGPQDPHTFNHQNLTHCSRHGSGP 615
PPG + P GP P + N + + GS P
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYP 584
Score = 37.0 bits (84), Expect = 0.061
Identities = 86/403 (21%), Positives = 131/403 (32%), Gaps = 87/403 (21%)
Query: 85 QSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHIDSSPYSPAYLSPPPESSWR 144
QS H P+ ST HH ++ Q+ ++ ++ H +S P PPP +
Sbjct: 469 QSTAHPPV----STHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP-------PPPGA--- 514
Query: 145 RTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGI 204
P L SS A H M+PS P P P+ LP +
Sbjct: 515 -----------------FPHPLEGGSSHHA-HPYAMSPSLGSLRPYPPGPAHLPPPHSQV 556
Query: 205 LDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQ-PANVP 263
+ P P + + + SS+S C PSP Q P P
Sbjct: 557 SYSQAGPNGPPVSSS------------SNSSSSTSQGSYPCS------HPSPSQGPQGAP 598
Query: 264 VLPPAMNTGGSLPDLTNLHFP-PPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRG 322
+P PP+PT T ST T + G
Sbjct: 599 -------------------YPFPPVPTVTTSSATL--------STVIATVASSPAGYKTA 631
Query: 323 MGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPAS------S 376
GP SP ++ + P S + P S P+ P + +
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 377 LARHVLPTTS-LGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPL 435
+ LP G PSL P + +S +++ + P+ TP + R P P
Sbjct: 692 VGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPP 751
Query: 436 SLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLS 478
++ P+ A +S + K + S VPL+ SKL+
Sbjct: 752 KVVDVPSHASQS-ARFNKHLDRGFNSCARSDLYFVPLEGSKLA 793
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 71.6 bits (174), Expect = 2e-12
Identities = 147/610 (24%), Positives = 199/610 (32%), Gaps = 101/610 (16%)
Query: 87 PLHSPLDSSRSTRHHGLVE---RVQRDPRRMVSPLRRYTRHIDSS--PYSPAYLSPPPES 141
P P S S H E +R P R +R + SS P S S P
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 142 SWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRR 201
R A + P KG P + D+A ++ SP T P+P + L S
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT---PSPSAALQS-- 315
Query: 202 GGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPAN 261
+ P +PA + L P S S+ P + PSP
Sbjct: 316 ------QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-------PSLQTLPSP----- 357
Query: 262 VPVLPPAMNTGG-SLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGIS 320
P PP+ T P L H P P PL P T P
Sbjct: 358 -PATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAP------------------ 397
Query: 321 RGMGLGPGYDAPGLHSPLSHPSLQ--SSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLA 378
P P L +P S P+ S L+ P+ QA + LQ S P P
Sbjct: 398 ------PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA- 450
Query: 379 RHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLL 438
P + P +S A S + S ++P L P P ++P SP P +P L
Sbjct: 451 ----PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 439 AGPADARRSQQQLPKQFS----------PTMSPTLSSITQGVPLDTSKLSTDQ------- 481
A P + Q P + P P + + L S L+T
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 482 -----RLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYP 536
++PP P +SP+L P +P TP P + ++ + G PP +S T
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSG 625
Query: 537 PGPSGHGQQSYHRP--MSDFNLGNLEQFSMESPSASLVL---DPPGFSEGP----GFLGG 587
P +GH + P + ++ G E + SP L P +S GP F G
Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGP-EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 684
Query: 588 EG------PMGGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGF 641
G P GP T + L SPG S AAA AG
Sbjct: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGAS 744
Query: 642 EVSAAGLELG 651
S LG
Sbjct: 745 SRSPKQARLG 754
Score = 55.8 bits (133), Expect = 1e-07
Identities = 116/459 (25%), Positives = 171/459 (37%), Gaps = 76/459 (16%)
Query: 126 DSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQ 185
D+S +P SP + RR+ A G E G PSA R ++ SV + S
Sbjct: 163 DTSGPTPGTPSP---AMARRSRAAGT---EVGLPRPAPSARPRPPTEGP-RKSVSSASEH 215
Query: 186 DTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSS-SRPRS 244
T T PS RR G P ++ + A LSS + S P +
Sbjct: 216 ST----TEPSPAARRRPSAGGGLQRPASRSLSSS------------ATPLSSPARSGPSA 259
Query: 245 CEVPGINIFPSPDQPANVPVL------PPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAY 298
P PS +P + L PP + +L L++ P P+ + A
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAA-LQSQAP 318
Query: 299 PSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSS 358
P+L +S+LT ++ + L P P +P S +L S + P QA+ S
Sbjct: 319 PTLPATPHSSSLT-----CQLATPLPLAP----PSPSAPPSLQTLPSPPATPPSQATTSL 369
Query: 359 PQPQLQGSHSH-PSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYP 417
P LQ +HS PS P S LA P AP + + SP P P
Sbjct: 370 GSPTLQATHSFLPSPPLSPLAT----------PPPQAPPALALPPLQAPPSPPASPPLSP 419
Query: 418 ASTPG-ASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSK 476
+TP +P+ V L L P + Q SP +SP+ + +Q P S
Sbjct: 420 LATPSPQAPNALAVHL--LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP---SL 474
Query: 477 LSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYP 536
+ ++PP P +SP P +P + P P + +PP + P
Sbjct: 475 AAPPLQVPPSPPASP-------PMSPSATPPPQAPPPLAAPPLQLAKPPPQA-------P 520
Query: 537 PGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDP 575
P + Q+ P + F + SPSASL + P
Sbjct: 521 PALATPPLQALPSPPASF-----PGQAPFSPSASLPMSP 554
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 68.6 bits (166), Expect = 2e-11
Identities = 135/542 (24%), Positives = 188/542 (34%), Gaps = 88/542 (16%)
Query: 153 PAEKGQLFRLPSALNRTSSDSALHTSVMN-PSPQDTYPGPTPPSILPSRRGGILDGEMDP 211
P+ G L R P++ + +SS + L + + PS + T P PS P +G L P
Sbjct: 219 PSAGGGLQR-PASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKG--LQALRPP 274
Query: 212 KVPAIEENLLDDKHLLKPWDAKKLS--SSSSRPRSCEVPGINIFPSPDQPANVPVLPPAM 269
+V + D L P + L+ S S+ P P + PSP P PP+
Sbjct: 275 QVTPPRK---DAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP------PATPPSQ 325
Query: 270 NTGG-SLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPG 328
T P L H P P PL P T P P
Sbjct: 326 ATTSLGSPTLQATHSFLPSP-PLSPLATPPPQAP------------------------PA 360
Query: 329 YDAPGLHSPLSHPSLQ--SSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTS 386
P L +P S P+ S L+ P+ QA + LQ S P P P +
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-----PFSP 415
Query: 387 LGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARR 446
P +S A S + S ++P L P P ++P SP P +P L A P +
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAK 475
Query: 447 SQQQLPKQFS----------PTMSPTLSSITQGVPLDTSKLSTDQ------------RLP 484
Q P + P P + + L S L+T ++P
Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535
Query: 485 PYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQ 544
P P +SP+L P +P TP P + ++ + G PP +S T P +GH
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDLAGHSS 594
Query: 545 QSYHRP--MSDFNLGNLEQFSMESPSASLVL---DPPGFSEGP----GFLGGEG------ 589
+ P + ++ G E + SP L P +S GP F G G
Sbjct: 595 SATSTPEELRGYDSGP-EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653
Query: 590 PMGGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLE 649
P GP T + L SPG S AAA AG S
Sbjct: 654 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713
Query: 650 LG 651
LG
Sbjct: 714 LG 715
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 66.6 bits (161), Expect = 7e-11
Identities = 152/602 (25%), Positives = 218/602 (36%), Gaps = 83/602 (13%)
Query: 120 RYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALH--- 176
R T+ +SP PA S PP+S A + PA L A++ SS +H
Sbjct: 435 RQTQASLTSPSRPA--STPPDSP--PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 177 --TSVMNPSPQDTYPGPTPPSILP--SRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDA 232
+S+ + SPQ P I+P + + + ++ L++ L P
Sbjct: 491 ALSSLASHSPQ----APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 233 KKLSSSSSRPR--------SCEV---PGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNL 281
+ S+ + P C + P P P+ P+++ PP + P L L
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGL 606
Query: 282 HFPP--PLPTP--------------LDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGL 325
PP PL TP P A P LS + S + + +
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 326 GPGYDAPGLHSPLSHPSLQ--SSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLP 383
P +P + +P S P+ S + P QA S P LQ S P+ P S + P
Sbjct: 667 PP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 384 TTS--LGHPSLSAPALSSSSSSSSTSS-------PVLGAP------SYPASTPGASPHHR 428
L P L P +S S S+ P+L AP S PAS P SP +
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP-MSPLAK 783
Query: 429 RVPLSPLSLLAGPADARRSQQ-QLPKQ--FSPTMSPTLSSITQGVPLDTSKLSTDQ-RLP 484
P +P +L P A S P Q FSP+ S +S + P L+ ++P
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 485 PYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQ 544
P P +SP+L P +P TP P + ++ + G PP +S T P +GH
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 545 QSYHRP--MSDFNLGNLEQFSMESPSASLVL---DPPGFSEGP----GFLGGEG------ 589
+ P + ++ G E + SP L P +S GP F G G
Sbjct: 903 SATSTPEELRGYDSGP-EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 961
Query: 590 PMGGPQDPHTFNHQNLTHCSRHGSGPNIILTGDSSPGFSKEIAAALAGVPGFEVSAAGLE 649
P GP T + L SPG S AAA AG S
Sbjct: 962 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Query: 650 LG 651
LG
Sbjct: 1022 LG 1023
Score = 65.5 bits (158), Expect = 2e-10
Identities = 117/404 (28%), Positives = 143/404 (35%), Gaps = 77/404 (19%)
Query: 163 PSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLD 222
P+A R S+ L P +P PS RG P+ PA
Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-------TPRAPAHPSQP-- 272
Query: 223 DKHLLKPWDAKKLSSSS-SRPRSCEVPGINIF-------PSPDQPANVPVLPPAMNTGGS 274
KP + L + PR P + PSP PV PP N
Sbjct: 273 -----KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV-PPPDNAATP 326
Query: 275 LPDLTNLHFPPPLPTPLD---PEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDA 331
LP L PPL TPL P +A PSL T+ + P
Sbjct: 327 LP--ATLPPSPPLATPLPLAPPSPSAPPSLQ----------TLPSPPATPPSQAPPSMTT 374
Query: 332 PGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLP-TTSLGHP 390
P + +P PSLQ+ P +Q S P LQ P S LA L TTSLG P
Sbjct: 375 PPMQAP---PSLQTI---PPIQVPHSLTSPSLQA-------PPSPLALSSLQATTSLGSP 421
Query: 391 SLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPL-SPLSLLAGPADARRSQQ 449
+L A + S T + L +PS PASTP SP PL +PLSL A P Q
Sbjct: 422 TLQATHSFLTMSPRQTQAS-LTSPSRPASTPPDSP-----PLQAPLSLPASPP----LQT 471
Query: 450 QLPKQFSPTMSP-------TLSSITQGVP------LDTSKLSTDQRLPPYPYSSPSLVLP 496
L SP SP LSS+ P L L T L P +P L
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531
Query: 497 TQP-HTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGP 539
T P SL P L + S + + + P + PP P
Sbjct: 532 TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
Score = 51.6 bits (122), Expect = 2e-06
Identities = 101/399 (25%), Positives = 139/399 (34%), Gaps = 45/399 (11%)
Query: 164 SALNRTSSDSALHTSVMNPSPQDTYPGP--TPPSILPSRRGGILDGEMDPKVPAIEENLL 221
S+ N S A P ++T PGP +P + R G L G+ ++ A EE +
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL-GQKGLRISA-EETVA 143
Query: 222 DDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNL 281
K P LS+ + R S PG PSP A T LP
Sbjct: 144 RGKATEAP-KRSALSAGARRDTSGPTPGT---PSPAMARR----SRAAGTEVGLPR---- 191
Query: 282 HFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHS----- 336
P P P P E S+S S S + T R G G P S
Sbjct: 192 --PAPSARPRPPTEGPRKSVS---SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
Query: 337 -PLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAP 395
PLS P+ S P+ + + +P +HPS P + + P +AP
Sbjct: 247 TPLSSPAR----SGPSARGTPRAP--------AHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 396 ALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQF 455
AL SSS + G + P P + L P LA P P
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 456 SPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSC 515
SP + +Q P S + + PP + P + +P +P SLQ P P
Sbjct: 355 QTLPSPPATPPSQAPP---SMTTPPMQAPPSLQTIPPIQVPHSLTSP-SLQAPPSPLALS 410
Query: 516 SVQ--SSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMS 552
S+Q +S G P + +H P + S RP S
Sbjct: 411 SLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAS 449
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/452 (25%), Positives = 155/452 (34%), Gaps = 96/452 (21%)
Query: 107 VQRDPRRMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSAL 166
VQ +P+ + +PL + SP LSPPPE S P E +L P L
Sbjct: 424 VQLEPQ-LEAPLNEEMPLLPPPEESP--LSPPPEESPTSP------PPEASRLSPPPEEL 474
Query: 167 NRTSSDSALHTS------VMNPSPQDTYPGPTPPS--ILPSRRGGILDGEMDPKVPAIEE 218
+ ALH S ++P P+++ P P S P + E P PA+E
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 219 NLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDL 278
L P +A LS P P P +P PP + S P
Sbjct: 535 PLSP------PPEASPLS-----------PPFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 279 TNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPL 338
+ PPP +P+ P A SR L P ++ SPL
Sbjct: 578 ESPMSPPPEESPMSPPPEA----------------------SR---LFPPFE----ESPL 608
Query: 339 SHPSLQSSLSNPNLQASLSSP---QPQLQGSHSHPSLPASSLAR-HVLPTTS-LGHPSLS 393
S P +S LS P + LS P P P P ++R LP S L P
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Query: 394 APALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPK 453
+P S ++ P S P SP P SP P D S LP
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP-----PPED---SLMSLPL 720
Query: 454 QFSPTM----SPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPG 509
+ SP + P L ++G L P P+ SP P +PH ++P
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPR--------PEEPHLSPR---PEEPHLSPQAEEPH 769
Query: 510 LPSQS-----CSVQSSGGQPPGRQSHYGTPYP 536
L Q C+V P + + +P P
Sbjct: 770 LSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP 801
Score = 55.8 bits (133), Expect = 1e-07
Identities = 101/428 (23%), Positives = 140/428 (32%), Gaps = 65/428 (15%)
Query: 126 DSSPYSPAY---LSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSV--- 179
+ SP SPA LSPPPE+S P E+ L P L + A S
Sbjct: 524 EESPPSPALETPLSPPPEASPLSP------PFEESPLSPPPEELPTSPPPEASRLSPPPE 577
Query: 180 ---MNPSPQDTYPGPTPPS--ILPSRRGGILDG--EMDPKVPAIEENLL----DDKHLLK 228
M+P P+++ P P + + P L E P P E + L +D +
Sbjct: 578 ESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSP 637
Query: 229 PWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLP 288
P + +S R +P ++ P P P+ PP + S P + PPP
Sbjct: 638 PPEESPMSPPPEVSRLSPLPVVSRLSPP--PEESPLSPPPEESPTSPPPEASRLSPPPED 695
Query: 289 TPLDPEETAYPSLSGGNSTSNLTHTMTHLGI------------SRGMGLGPGYDAPGLHS 336
+P P P+ S S ++ + + S G L P + P L
Sbjct: 696 SPTSPPPEDSPA-SPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSP 754
Query: 337 PLSHPSLQSSLSNPNLQASLSSP-------QPQLQGSHSHPSLPASSLARHVLPTTSLGH 389
P L P+L P +P L P L H+ P T H
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814
Query: 390 --PSLSAPALS----SSSSSSSTSSPVLGAP------SYPASTPGASPHHRRVPLSPLSL 437
P P LS S S + P L S P SP + P P
Sbjct: 815 LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP--- 871
Query: 438 LAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSL---V 494
G A P P++SP L P + + LP P PSL +
Sbjct: 872 --GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Query: 495 LPTQPHTP 502
+P P P
Sbjct: 930 MPPDPLPP 937
Score = 55.1 bits (131), Expect = 2e-07
Identities = 92/347 (26%), Positives = 130/347 (37%), Gaps = 66/347 (19%)
Query: 175 LHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKV--PAIEENLLDDKHLLKPWDA 232
LH S P + P P P + P L + + P EE+ L + L KP +
Sbjct: 804 LHLSPQTEEPHLS-PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE-LEKPPLS 861
Query: 233 KKLSSSSSRPRSCEVPG-INIFPSPDQPANVPVL-PPAMNTGGSLP-------------- 276
+ P C P + +FP P +P+ P+L PA++ G P
Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG 921
Query: 277 --DLTNLHFPP-PLPTPLDPEETAY--PSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDA 331
L+ PP PLP PL P TA P+LS L + G S
Sbjct: 922 EPSLSPQLMPPDPLPPPLSPIITAAAPPALS---PLGELEYPFGAKGDS----------- 967
Query: 332 PGLHSPLSHPSLQSSLSNPNLQASLSSPQPQ----LQGSHSHPSLPASSLARHVLPTTSL 387
SPL+ P L++ +S P +A+ + P+P L S P PAS + LP
Sbjct: 968 -DPESPLAAPILETPISPPP-EANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQC- 1024
Query: 388 GHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRS 447
P L + +S S S P L P S P PLSP+ + G +D
Sbjct: 1025 -SPLLQHSLVPQNSPPSQCSPPAL-----PLSVPS--------PLSPIGKVVGVSDEAEL 1070
Query: 448 QQQLPKQFSPTMSPTLS-SITQGVPLDTSKLSTDQRLPPYPYSSPSL 493
+ ++ S P L S T +P LS P P +P+L
Sbjct: 1071 HEMETEKVSEPECPALEPSATSPLPSPMGDLSC-----PAPSPAPAL 1112
Score = 49.7 bits (117), Expect = 9e-06
Identities = 78/277 (28%), Positives = 97/277 (35%), Gaps = 34/277 (12%)
Query: 283 FPPPLP--TPLDPEETAYPSLSGGNSTSNLTHTMTH-----------LGISRGMGLGPGY 329
F PP P TP D + Y + G ++T LG G+ L P
Sbjct: 372 FSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG-KAGVQLEPQL 430
Query: 330 DAP-GLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLG 388
+AP PL P +S LS P ++ S P + S LPAS L + + L
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLE 490
Query: 389 HPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHH--RRVPLSPLSLLAGPADARR 446
LS P S S SSP P S P SP PLSP P +A
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP------PPEA-- 542
Query: 447 SQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPP--YPYSSPSLVLPTQPHTPKS 504
S P + SP +SP + P + S+LS PP P S P P P S
Sbjct: 543 SPLSPPFEESP-LSPPPEELPTSPPPEASRLSP----PPEESPMSPPPEESPMSPPPEAS 597
Query: 505 LQQPGLPSQSCS--VQSSGGQPPGRQSHYGTPYPPGP 539
P S + S PP S P P
Sbjct: 598 RLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634
Score = 45.8 bits (107), Expect = 1e-04
Identities = 100/418 (23%), Positives = 147/418 (35%), Gaps = 70/418 (16%)
Query: 139 PESSWRRTMAWG-NFPAEKGQLFRLPSALNRTSSDSALHTSVMNPS-PQDTYPGPTPPSI 196
P+ ++ +A G PA+ Q F P AL T + + ++P+ + GP+
Sbjct: 3987 PQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPS---- 4042
Query: 197 LPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSP 256
+ +GG L P+ A E P + K S S+ + + P P
Sbjct: 4043 --THQGGPLAIGTTPESMATE-----------PGEVKPSLSGDSQL-------LLVQPQP 4082
Query: 257 D-QPANVPVLPPAMNTGGSLPDLTNLHFP-----------PPLPTPLDPEETAYPSLSGG 304
QP+++ + PP G ++ LH P A PS+S G
Sbjct: 4083 QPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLG 4142
Query: 305 NSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPN--LQASLSSPQPQ 362
+ ++T + LG + M P + G P P LQS P + ++ + Q
Sbjct: 4143 DQPGSMTQNL--LGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQ 4200
Query: 363 LQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPG 422
LQG L + RH+ P L A + S V P Y
Sbjct: 4201 LQGV-----LAKNPQLRHLSPQQQ---QQLQALLMQRQLQQSQA---VRQTPPYQEPGTQ 4249
Query: 423 ASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQR 482
SP + P L P Q+L P P L P LST
Sbjct: 4250 TSPLQGLLGCQP-QLGGFPGPQTGPLQELGAGPRPQGPPRL-------PAPPGALSTGPV 4301
Query: 483 LPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPS 540
L P + P P+ P PK Q LPS S + + PP +H GTP P GP+
Sbjct: 4302 LGPVHPTPP----PSSPQEPKRPSQ--LPSPSSQLPTEAQLPP---THPGTPKPQGPT 4350
Score = 32.0 bits (71), Expect = 2.0
Identities = 52/219 (23%), Positives = 79/219 (36%), Gaps = 31/219 (14%)
Query: 332 PGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPS--------------LPASSL 377
PG P P + S P L + L +P+++ HPS A+SL
Sbjct: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAANSL 3150
Query: 378 ARHVLPTTS-LGHPSL---SAPALSSSSSSSSTSSPVLGAP------SYPASTPGASPHH 427
+ P S +G + P SS ++ S G P P S PG S
Sbjct: 3151 GLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLL 3210
Query: 428 RRVPL--SPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPP 485
+ L L+L GPA S +L K S ++ L + + + L+ K ++
Sbjct: 3211 EKFELESGALTLPGGPA---ASGDELDKMESSLVASELPLLIEDL-LEHEKKELQKKQQL 3266
Query: 486 YPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQP 524
P+ Q L PG P+Q+ S+ G P
Sbjct: 3267 SAQLQPAQQQQQQQQQHSLLSAPG-PAQAMSLPHEGSSP 3304
Score = 31.6 bits (70), Expect = 2.6
Identities = 40/171 (23%), Positives = 57/171 (33%), Gaps = 19/171 (11%)
Query: 135 LSPPPESSWRRTMAWGNFPAEKGQLFRLPSA----LNRTSSDSALH-TSVMNPSPQDTYP 189
L + W++ A R PS L R + S L S P P + P
Sbjct: 2810 LQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVP 2869
Query: 190 GPTPPSILPSRRGGI----------LDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSS 239
GP P+ R + G+ P+ P + +D H L P + L+ S
Sbjct: 2870 GPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYP-VSEDPHRLAPEGLRGLAVSG 2928
Query: 240 ---SRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPL 287
+P + P +N P P LP + P T L P PL
Sbjct: 2929 LPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPL 2979
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 62.0 bits (149), Expect = 2e-09
Identities = 137/601 (22%), Positives = 199/601 (33%), Gaps = 157/601 (26%)
Query: 3 TSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYT 62
+SG N P +A+ S+++ + + K + +K + EE + S + Q +K+
Sbjct: 54 SSGRNSPSAASTSSNDSKAETVKKSAKKVK--------EEASSPLKSNKRQREKVASDTE 105
Query: 63 RSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT 122
+ +I + + S SRS G DP+ +
Sbjct: 106 EADRTSSKKTKTQEISRPNSPSEGEGES--SDSRSVNDEG-----SSDPKDIDQ------ 152
Query: 123 RHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNP 182
D+ SP+ SP S + A++ L P AL + + +S
Sbjct: 153 ---DNRSTSPSIPSPQDNESD------SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
Query: 183 SPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRP 242
+PQ PGPTP + + P + S + ++P
Sbjct: 204 TPQLPTPGPTPSAT-----------------------------AVPPQGSPTASQAPNQP 234
Query: 243 R--SCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS 300
+ + VP +I PA P PP+ + PPP P+P P + P
Sbjct: 235 QAPTAPVPHTHI---QQAPALHPQRPPSPH-------------PPPHPSPHPPLQ---PL 275
Query: 301 LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ 360
S +H L G GP PG HS + P LQ +P P
Sbjct: 276 TGSAGQPSAPSHAQPPL-----HGQGP----PGPHSLQAGPLLQ----HPGPPQPFGLPP 322
Query: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST 420
QG + PA++ H SL PA S S+ + P P PA
Sbjct: 323 QASQGQAPLGTSPAAAYP----------HTSLQLPA---SQSALQSQQPPREQPLPPA-- 367
Query: 421 PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD 480
P A PH + P +P+ QLP + P LS S S +
Sbjct: 368 PLAMPHIKPPPTTPI-------------PQLPAPQAHKHPPHLSG--------PSPFSMN 406
Query: 481 QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLP--SQSCSVQSSGGQPPGRQSHYGTPYPPG 538
LPP P P L T H P S P L QS + SS QPPG PP
Sbjct: 407 ANLPPPPALKPLSSLST--HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN--LPPP 462
Query: 539 PSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPH 598
P+ H H+ V P F++ P GG P+ P P
Sbjct: 463 PASHPPTGLHQ----------------------VAPQPPFAQHPFVPGGPPPITPPTCPS 500
Query: 599 T 599
T
Sbjct: 501 T 501
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.0 bits (149), Expect = 2e-09
Identities = 137/601 (22%), Positives = 199/601 (33%), Gaps = 157/601 (26%)
Query: 3 TSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYT 62
+SG N P +A+ S+++ + + K + +K + EE + S + Q +K+
Sbjct: 608 SSGRNSPSAASTSSNDSKAETVKKSAKKVK--------EEASSPLKSNKRQREKVASDTE 659
Query: 63 RSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT 122
+ +I + + S SRS G DP+ +
Sbjct: 660 EADRTSSKKTKTQEISRPNSPSEGEGES--SDSRSVNDEG-----SSDPKDIDQ------ 706
Query: 123 RHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNP 182
D+ SP+ SP S + A++ L P AL + + +S
Sbjct: 707 ---DNRSTSPSIPSPQDNESD------SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757
Query: 183 SPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRP 242
+PQ PGPTP + + P + S + ++P
Sbjct: 758 TPQLPTPGPTPSAT-----------------------------AVPPQGSPTASQAPNQP 788
Query: 243 R--SCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS 300
+ + VP +I PA P PP+ + PPP P+P P + P
Sbjct: 789 QAPTAPVPHTHI---QQAPALHPQRPPSPH-------------PPPHPSPHPPLQ---PL 829
Query: 301 LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ 360
S +H L G GP PG HS + P LQ +P P
Sbjct: 830 TGSAGQPSAPSHAQPPL-----HGQGP----PGPHSLQAGPLLQ----HPGPPQPFGLPP 876
Query: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST 420
QG + PA++ H SL PA S S+ + P P PA
Sbjct: 877 QASQGQAPLGTSPAAAYP----------HTSLQLPA---SQSALQSQQPPREQPLPPA-- 921
Query: 421 PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD 480
P A PH + P +P+ QLP + P LS S S +
Sbjct: 922 PLAMPHIKPPPTTPI-------------PQLPAPQAHKHPPHLSG--------PSPFSMN 960
Query: 481 QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLP--SQSCSVQSSGGQPPGRQSHYGTPYPPG 538
LPP P P L T H P S P L QS + SS QPPG PP
Sbjct: 961 ANLPPPPALKPLSSLST--HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN--LPPP 1016
Query: 539 PSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPH 598
P+ H H+ V P F++ P GG P+ P P
Sbjct: 1017 PASHPPTGLHQ----------------------VAPQPPFAQHPFVPGGPPPITPPTCPS 1054
Query: 599 T 599
T
Sbjct: 1055 T 1055
Score = 34.7 bits (78), Expect = 0.31
Identities = 73/329 (22%), Positives = 104/329 (31%), Gaps = 51/329 (15%)
Query: 285 PPLPTPLDPEETAYP-------SLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSP 337
PP+ P+DP + LSG +S + + G P G SP
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPA-SPDGRTSP 601
Query: 338 LSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPAL 397
++ S ++P+ AS SS + + + + S
Sbjct: 602 INEDIRSSGRNSPSA-ASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEE 660
Query: 398 SSSSSSSSTSSPVLGAPSYPASTPGASPHHRRV-------------------PLSPLSLL 438
+ +SS T + + P+ P+ G S R V P P S
Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP-SPQ 719
Query: 439 AGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLP-PYPYSSPSLV--- 494
+D+ S QQ Q P P L + T P +S +LP P P S + V
Sbjct: 720 DNESDSDSSAQQQMLQAQP---PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ 776
Query: 495 -LPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSD 553
PT P Q P P +Q + P R PP P S H P+
Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR--------PPSPHPPPHPSPHPPLQP 828
Query: 554 FNLGNLEQFSMESPSASLVLDPPGFSEGP 582
S PSA PP +GP
Sbjct: 829 LT------GSAGQPSAPSHAQPPLHGQGP 851
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 62.0 bits (149), Expect = 2e-09
Identities = 137/601 (22%), Positives = 199/601 (33%), Gaps = 157/601 (26%)
Query: 3 TSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYT 62
+SG N P +A+ S+++ + + K + +K + EE + S + Q +K+
Sbjct: 608 SSGRNSPSAASTSSNDSKAETVKKSAKKVK--------EEASSPLKSNKRQREKVASDTE 659
Query: 63 RSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYT 122
+ +I + + S SRS G DP+ +
Sbjct: 660 EADRTSSKKTKTQEISRPNSPSEGEGES--SDSRSVNDEG-----SSDPKDIDQ------ 706
Query: 123 RHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNP 182
D+ SP+ SP S + A++ L P AL + + +S
Sbjct: 707 ---DNRSTSPSIPSPQDNESD------SDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 757
Query: 183 SPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRP 242
+PQ PGPTP + + P + S + ++P
Sbjct: 758 TPQLPTPGPTPSAT-----------------------------AVPPQGSPTASQAPNQP 788
Query: 243 R--SCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPS 300
+ + VP +I PA P PP+ + PPP P+P P + P
Sbjct: 789 QAPTAPVPHTHI---QQAPALHPQRPPSPH-------------PPPHPSPHPPLQ---PL 829
Query: 301 LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQ 360
S +H L G GP PG HS + P LQ +P P
Sbjct: 830 TGSAGQPSAPSHAQPPL-----HGQGP----PGPHSLQAGPLLQ----HPGPPQPFGLPP 876
Query: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPAST 420
QG + PA++ H SL PA S S+ + P P PA
Sbjct: 877 QASQGQAPLGTSPAAAYP----------HTSLQLPA---SQSALQSQQPPREQPLPPA-- 921
Query: 421 PGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTD 480
P A PH + P +P+ QLP + P LS S S +
Sbjct: 922 PLAMPHIKPPPTTPI-------------PQLPAPQAHKHPPHLSG--------PSPFSMN 960
Query: 481 QRLPPYPYSSPSLVLPTQPHTPKSLQQPGLP--SQSCSVQSSGGQPPGRQSHYGTPYPPG 538
LPP P P L T H P S P L QS + SS QPPG PP
Sbjct: 961 ANLPPPPALKPLSSLST--HHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN--LPPP 1016
Query: 539 PSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPH 598
P+ H H+ V P F++ P GG P+ P P
Sbjct: 1017 PASHPPTGLHQ----------------------VAPQPPFAQHPFVPGGPPPITPPTCPS 1054
Query: 599 T 599
T
Sbjct: 1055 T 1055
Score = 34.7 bits (78), Expect = 0.31
Identities = 73/329 (22%), Positives = 104/329 (31%), Gaps = 51/329 (15%)
Query: 285 PPLPTPLDPEETAYP-------SLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSP 337
PP+ P+DP + LSG +S + + G P G SP
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPA-SPDGRTSP 601
Query: 338 LSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPAL 397
++ S ++P+ AS SS + + + + S
Sbjct: 602 INEDIRSSGRNSPSA-ASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEE 660
Query: 398 SSSSSSSSTSSPVLGAPSYPASTPGASPHHRRV-------------------PLSPLSLL 438
+ +SS T + + P+ P+ G S R V P P S
Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIP-SPQ 719
Query: 439 AGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLP-PYPYSSPSLV--- 494
+D+ S QQ Q P P L + T P +S +LP P P S + V
Sbjct: 720 DNESDSDSSAQQQMLQAQP---PALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ 776
Query: 495 -LPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSD 553
PT P Q P P +Q + P R PP P S H P+
Sbjct: 777 GSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQR--------PPSPHPPPHPSPHPPLQP 828
Query: 554 FNLGNLEQFSMESPSASLVLDPPGFSEGP 582
S PSA PP +GP
Sbjct: 829 LT------GSAGQPSAPSHAQPPLHGQGP 851
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 61.6 bits (148), Expect = 2e-09
Identities = 124/476 (26%), Positives = 159/476 (33%), Gaps = 90/476 (18%)
Query: 170 SSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEE---NLLDDKHL 226
+S HT ++P P P P P G G + P+ P++ + L L
Sbjct: 130 ASPQMFHT--VSPGPPSARPPCRVPPTTPLNGG---PGSLPPEPPSVSQAFPTLAGPGGL 184
Query: 227 LKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSL------PDLTN 280
P A + S S G P+P P + + P+ N G +L DL +
Sbjct: 185 FPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGS 244
Query: 281 LHFP---------PPL--------PTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGM 323
P PPL P PL P P+ G S ++ HL +
Sbjct: 245 PPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNL-PAHPGPASQPPVSSATMHLPLV--- 300
Query: 324 GLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLP 383
LGP AP + P + P L SSL + +A HP LP P
Sbjct: 301 -LGPLGGAPTVEGPGAPPFLASSLLSAAAKAQ-------------HPPLPP--------P 338
Query: 384 TTSLGH-PSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPH--HRRVPLSPLSLLAG 440
+T G P AP+ S SSS + P+ G P R P +P +
Sbjct: 339 STLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQP 398
Query: 441 PADARRSQQQLPKQFS----PTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLP 496
+ SQ LP S PT P+ S + + L +D LPP P S P
Sbjct: 399 FSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNL------LGSDAHLPPPPTLSSGS--P 450
Query: 497 TQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYP--PGPS-----GHGQQSYHR 549
QP P PG S S S PP P P PS G G
Sbjct: 451 PQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLP 510
Query: 550 PMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGG---EGPMGGPQDPHTFNH 602
P L E F SP L L GF PG LG +G P NH
Sbjct: 511 P-----LAGGEAFPFPSPEQGLALSGAGF---PGMLGALPLPLSLGQPPPSPLLNH 558
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 60.1 bits (144), Expect = 7e-09
Identities = 123/535 (22%), Positives = 171/535 (31%), Gaps = 144/535 (26%)
Query: 146 TMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGIL 205
T A G+ PA +G + A + TS NP GP +LP++
Sbjct: 276 TPALGSLPAGRGPRGTVAPA----TPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSA-- 329
Query: 206 DGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVL 265
+DP +PA + S+ PR P Q +
Sbjct: 330 SNALDPMLPA------------------SVGGSTRTPRPAAA-------QPSQKITATKI 364
Query: 266 PPAMNTGGSLPDLTNLHFPPPLPT----PLDPEETAYPSLSGGNSTSNLTHTMTHLGISR 321
P ++ T S P + + P PT P ++A P+ TS +
Sbjct: 365 PKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPAEK 424
Query: 322 GMGLGPGYDAPGLHSPLSHPSLQSSLSNP---------NLQASLSSPQPQLQGSHSHPSL 372
+ PG P S P SS P + + S P +H P
Sbjct: 425 PIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPF 484
Query: 373 PASSL---------------ARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYP 417
A S A V PT+ P +APA+ + S+ + S +G+ +
Sbjct: 485 TALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPR-TAPAVPTPGSAPTGSKKPIGSEASK 543
Query: 418 ASTPGASPHH----------RRVPLSPLSLLAGPADARRSQQQLPK------QF-SPTMS 460
+ P +SP R VPLS L+ P + SQQ P QF S +
Sbjct: 544 KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPR 603
Query: 461 PTLSSIT----------------------------QGVP-LDTSKLSTDQRLPPYPYSSP 491
PT S + G+P L + R PP PY +P
Sbjct: 604 PTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNP 663
Query: 492 SLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQ-------------PPGRQSHYGTPYPPG 538
L P P + Q G P S G + PPGR+ H G PG
Sbjct: 664 GL-----PGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGY---PG 715
Query: 539 PSGH-GQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMG 592
P+GH G+Q P SP A PG PG +G GP G
Sbjct: 716 PAGHPGEQGQPGPEG-------------SPGAK---GYPGRQGLPGPVGDPGPKG 754
Score = 31.6 bits (70), Expect = 2.6
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 19/86 (22%)
Query: 524 PPGRQSHYGTPYPPGPSGH----GQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFS 579
P G Q G PPGP G GQQ +LG+ + PS PPG
Sbjct: 1073 PAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERG--HLGSRGFPGIPGPSG-----PPGTK 1125
Query: 580 EGPGFLGGEGPMG--------GPQDP 597
PG G +GP G GP+ P
Sbjct: 1126 GLPGEPGPQGPQGPIGPPGEMGPKGP 1151
>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
Length = 1426
Score = 59.3 bits (142), Expect = 1e-08
Identities = 123/474 (25%), Positives = 174/474 (36%), Gaps = 111/474 (23%)
Query: 263 PVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGG-----NSTSNLTHTMTHL 317
P LP + G + L NL P+ P++ LS N +SN T T
Sbjct: 783 PFLPMSQGPGSN-SGLRNLR------EPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAP 835
Query: 318 GISRGMG--------LGPGYDAPGLH---SPLSHPSLQSSLSNPNLQASLSSPQP--QLQ 364
+ RG+G G +PG++ SP H L +P+ +L SPQ QL
Sbjct: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPS--GNLKSPQTPSQLA 893
Query: 365 GSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGAS 424
G + P+ AS + VL + + L +P+L + S ++S P P +PG
Sbjct: 894 GMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSS------PKPPLQSPGIP 947
Query: 425 PHHRRVPL---SPLSL----LAGPADARRSQQ-------QLPKQFSPTM--SPTLS---- 464
P+H + PL SP L GP SQ LP TM PTLS
Sbjct: 948 PNH-KAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPL 1006
Query: 465 ----------SITQGVPL--DTSK--LSTDQRLPPY---------------------PYS 489
++ PL D K S+D PP S
Sbjct: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS 1066
Query: 490 SPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGH----GQQ 545
P+ V+P +P + QP S S + S P H G P PG H G
Sbjct: 1067 GPNPVVPMPTLSPMGMTQP--LSHSNQMPSPNAVGPNIPPH-GVPMGPGLMSHNPIMGHG 1123
Query: 546 SYHRPM-SDFNLGNLEQF-SMESPSASLVLDPPGFSEG----PGFLG--GEGPMGGPQD- 596
S PM +G + F ++SP + G S G PG +G GEGP+G P +
Sbjct: 1124 SQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNL 1183
Query: 597 PHTFNHQNLTHCSRHGSGPNIILTGDS------SPGFSKEIAAALAGVPGFEVS 644
P + L G + + G+S P + I G+P F++S
Sbjct: 1184 PQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLS 1237
Score = 43.5 bits (101), Expect = 7e-04
Identities = 83/394 (21%), Positives = 137/394 (34%), Gaps = 57/394 (14%)
Query: 239 SSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNL---------HFPPPLPT 289
SS P+ P N SP V V PP + + P L + P+
Sbjct: 3 SSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPS 62
Query: 290 PLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLG-------------PGYDAPGLHS 336
P D S SGG++ L +G+ G G G +D +
Sbjct: 63 PCD-------SKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGT 115
Query: 337 PLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPA 396
P ++ S ++++ S P + S+ + P SS H T + P+ PA
Sbjct: 116 PNDDSDIKECNSADHIKSQDSQHTPHSM-TPSNATAPRSSTPSHGQTTATEPTPAQKTPA 174
Query: 397 LSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFS 456
S+ ++ A S H + + + P + + S + +
Sbjct: 175 KVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPL 234
Query: 457 PTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCS 516
P P ++ Q ++S+ + Q PP P +P P P P + PG+ ++
Sbjct: 235 PQQPPAPANQDQ----NSSQNTRLQPTPPIPAPAPK---PAAPPRPLDRESPGVENK--- 284
Query: 517 VQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPP 576
+ S G P TP PP +G +R ++ + G+ S SA PP
Sbjct: 285 LIPSVGSPAS-----STPLPPDGTGPNSTPNNRAVTPVSQGS------NSSSADPKAPPP 333
Query: 577 GFSEGPGFLGGEGPMGGPQDPHTFNHQNLTHCSR 610
P GE P G ++P + + L H R
Sbjct: 334 -----PPVSSGEPPTLG-ENPDGLSQEQLEHRER 361
Score = 43.5 bits (101), Expect = 7e-04
Identities = 140/646 (21%), Positives = 211/646 (32%), Gaps = 145/646 (22%)
Query: 109 RDPRRMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNR 168
R+ R + P +R + P P L+P + T P ++G L R P L+
Sbjct: 798 RNLREPIGPDQRTNSRLSHMP--PLPLNPSSNPTSLNTAP----PVQRG-LGRKP--LDI 848
Query: 169 TSSDSALHTSVMNP---------------SPQDTYPGPTPPSILPSRRGGILDGEMDPKV 213
+ + S +H+ +NP SP P PS L G
Sbjct: 849 SVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSP 908
Query: 214 PAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPP---AMN 270
P + HL P S P SP P P +PP A
Sbjct: 909 PVLGSAAASPVHLKSP--------------SLPAPSPGWTSSPKPPLQSPGIPPNHKAPL 954
Query: 271 TGGSLPDLTNLHFP-PPLPTPLDPEETAYPSLSGGNSTSNLTHTM------THLGISRGM 323
T S L N+ PP PT P P G+ S+ +TM + +S M
Sbjct: 955 TMASPAMLGNVESGGPPPPTASQPASVNIP----GSLPSSTPYTMPPEPTLSQNPLSIMM 1010
Query: 324 GLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVL- 382
+ P +PL H ++++ S+ + S + P L ++ P + ++ +
Sbjct: 1011 SRMSKFAMPS-STPLYHDAIKTVASSDD--DSPPARSPNLPSMNNMPGMGINTQNPRISG 1067
Query: 383 PTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPA 442
P + P+LS ++ S S+ PS A P PH VP+ P + P
Sbjct: 1068 PNPVVPMPTLSPMGMTQPLSHSNQM------PSPNAVGPNIPPHG--VPMGPGLMSHNPI 1119
Query: 443 DARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPH-- 500
SQ+ P + G P + + + P+P++ PS + P
Sbjct: 1120 MGHGSQEP----------PMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGM 1169
Query: 501 ---------TPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRP- 550
P +L Q + C GG P + G P + Q RP
Sbjct: 1170 GFPGEGPLGRPSNLPQSSADAALCKPGGPGG--PDSFTVLGNSMPSVFTDPDLQEVIRPG 1227
Query: 551 ---MSDFNLGNLEQFSMESPSASLVLDP----PGFSE----GPGF--------------- 584
+ +F+L + E PS +L P PG + GPGF
Sbjct: 1228 ATGIPEFDLSRI--IPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMG 1285
Query: 585 -----LGGEGPMG---------------GPQDPHTFNHQNLTHCSRHGSGPNIILTGDSS 624
+GG GP+G P P F Q + P T
Sbjct: 1286 LALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP-AQSTMPGQ 1344
Query: 625 PGFSKEIAAALAGVPGFEVSAAGLELGLGLEDELRMEPLGLEGLNM 670
P AAA+ +PG + AGL G P+G G+ M
Sbjct: 1345 PTLMSNPAAAVGMIPGKDRGPAGLYTHPG--------PVGSPGMMM 1382
>gi|38373671 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/296 (25%), Positives = 107/296 (36%), Gaps = 74/296 (25%)
Query: 256 PDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMT 315
P + LP + G L + N PP+ P P T+ ++ S ++ +
Sbjct: 95 PSSTVQMQRLPGSQPFGSPLAPVGN---QPPVLQPYGPPPTS-AQVATQLSGMQISGAVA 150
Query: 316 HLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPAS 375
S G+G GP +SL++ AS S P L GS+ P
Sbjct: 151 PAPPSSGLGFGP----------------PTSLAS----ASGSFPNSGLYGSYPQGQAPPL 190
Query: 376 SLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPL 435
S A+ GHP + P S+ S +SS + P G P P+ T PL P
Sbjct: 191 SQAQ--------GHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTG---------PLLPG 233
Query: 436 SLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVL 495
GP+ ++ + +SS Q +P T LPP
Sbjct: 234 QSFGGPSVSQPNH--------------VSSPPQALPPGTQMTGPLGPLPPM--------- 270
Query: 496 PTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPM 551
H+P QQPG Q S G G QS+YG PYP P+ Q +P+
Sbjct: 271 ----HSP---QQPGYQPQQ---NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPL 316
>gi|38373669 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 58.5 bits (140), Expect = 2e-08
Identities = 75/296 (25%), Positives = 107/296 (36%), Gaps = 74/296 (25%)
Query: 256 PDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMT 315
P + LP + G L + N PP+ P P T+ ++ S ++ +
Sbjct: 95 PSSTVQMQRLPGSQPFGSPLAPVGN---QPPVLQPYGPPPTS-AQVATQLSGMQISGAVA 150
Query: 316 HLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPAS 375
S G+G GP +SL++ AS S P L GS+ P
Sbjct: 151 PAPPSSGLGFGP----------------PTSLAS----ASGSFPNSGLYGSYPQGQAPPL 190
Query: 376 SLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPL 435
S A+ GHP + P S+ S +SS + P G P P+ T PL P
Sbjct: 191 SQAQ--------GHPGIQTPQRSAPSQASSFTPPASGGPRLPSMTG---------PLLPG 233
Query: 436 SLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVL 495
GP+ ++ + +SS Q +P T LPP
Sbjct: 234 QSFGGPSVSQPNH--------------VSSPPQALPPGTQMTGPLGPLPPM--------- 270
Query: 496 PTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPM 551
H+P QQPG Q S G G QS+YG PYP P+ Q +P+
Sbjct: 271 ----HSP---QQPGYQPQQ---NGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPL 316
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 58.2 bits (139), Expect = 3e-08
Identities = 101/401 (25%), Positives = 134/401 (33%), Gaps = 94/401 (23%)
Query: 215 AIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGS 274
A + LLD + KP + + PR E + + D P + LPP M G
Sbjct: 702 AARQQLLDRELKKKP-PPRPTAPKPLLPRREESEAVE---AGDPPEELRSLPPDMVAGPR 757
Query: 275 LPD-----LTNLHFPP-PLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPG 328
LPD T LHFPP P P+ P GP
Sbjct: 758 LPDTFLGSATPLHFPPSPFPSSTGP--------------------------------GPH 785
Query: 329 YDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLG 388
Y LS P + S P QP+ G H+ P P +L
Sbjct: 786 Y--------LSGPLPPGTYSGPT-----QLIQPRAPGPHAMPVAPGPAL----------- 821
Query: 389 HPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQ 448
APA + SSP G S P G +P +P +P +GP
Sbjct: 822 ---YPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGP------- 871
Query: 449 QQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPY--SSPSLVLPTQPHTPKSLQ 506
+L P + T+ SI +P T+ PP P P LPT P +
Sbjct: 872 -ELAMAVRPA-TTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAK 929
Query: 507 QPGLPSQSCSVQSSGGQPPGRQSHYGTPYP-PGPSGHGQQSY--HRPMSDFNLGNLEQFS 563
QP +P+Q S G P G + P P P P H Q++ P L + F
Sbjct: 930 QP-IPAQH---HFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFP 985
Query: 564 MESPSASLVLDPPGFSEGPGFLGGEGP-------MGGPQDP 597
++P P ++ PG LG P G QDP
Sbjct: 986 PQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDP 1026
Score = 40.0 bits (92), Expect = 0.007
Identities = 72/255 (28%), Positives = 85/255 (33%), Gaps = 42/255 (16%)
Query: 236 SSSSSRPRSCEVPGINIFP-SPDQPANVPVLPPAMNTGGSLPDLTNLHF----PPPLPTP 290
S ++ RP P FP P QP P PA G P HF P P P
Sbjct: 893 SHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPA---GAKQPIPAQHHFSSGIPAGFPAP 949
Query: 291 L-----DPEETAYPSLSGGNSTSN--LTHTMTHLGISRGMGLGP--------------GY 329
P +PS + G L HL + GL P G
Sbjct: 950 RIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQ 1009
Query: 330 DAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTS-LG 388
P LH+ L Q L P +L P P P P LA P+T +G
Sbjct: 1010 PPPPLHTQLYPGPAQDPL--PAHSGALPFPSP------GPPQPPHPPLAYGPAPSTRPMG 1061
Query: 389 HPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLS--PLSLLAGPADARR 446
+ SS+ ST SP L PS PA +PG P R P + P L G A A
Sbjct: 1062 PQAAPLTIRGPSSAGQSTPSPHL-VPS-PAPSPGPGPVPPRPPAAEPPPCLRRGAAAADL 1119
Query: 447 SQQQLPKQFSPTMSP 461
Q T SP
Sbjct: 1120 LSSSPESQHGGTQSP 1134
Score = 31.6 bits (70), Expect = 2.6
Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 8/95 (8%)
Query: 342 SLQSSLSNPNLQ--ASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSS 399
S+Q++++ +++ L SP L G P LP +SL S PS S P LSS
Sbjct: 1497 SIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPE------STPIPSSSPPPLSS 1550
Query: 400 SSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSP 434
+ P P+S P +S L+P
Sbjct: 1551 PLPEAPQPKEEPPVPEAPSSGPPSSSLELLASLTP 1585
>gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]
Length = 632
Score = 57.8 bits (138), Expect = 3e-08
Identities = 118/446 (26%), Positives = 154/446 (34%), Gaps = 71/446 (15%)
Query: 190 GPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPG 249
GP+ PS LP+ +G + P E A PR +
Sbjct: 149 GPSGPSELPAAQGRLAPDSAGEGAPGREP------------PASPAPPGKEHPRDLKFSI 196
Query: 250 INIFPSPDQPANVPVLPPAMNTGGSLPDLTNLH--------FPPPLPTPLDPEETAYPSL 301
I SPD + PP + G P L + LPTP+ L
Sbjct: 197 DYILSSPDPFPGLK--PPCLAQEGRYPRLEKVSPQCQRQTLSKRGLPTPVS-------IL 247
Query: 302 SGGNSTSNLTHTMTHLGISRGMGLG-PGYDAPGLHS--------PLSHPSLQSSLSNPNL 352
+ +SR + G P D P L + L PS Q+ + +
Sbjct: 248 INSQIQGHQQGVTGQAVVSRPLDAGWPWMDGPPLQAVFAPAPNHTLQRPSEQTCPQDLHT 307
Query: 353 QASLSSPQ-PQLQGSHSHPSLP--ASSLARHVLPTT--SLGHPSLSAPALSSSSSSSSTS 407
+ SLSSPQ P +GS S P P SL+ P T SL P S SS +
Sbjct: 308 RGSLSSPQDPHTRGSLSSPKDPHTRGSLSCPQDPHTRGSLSCPQDPHTRGSLSSPQDPHT 367
Query: 408 SPVLGAPSYPASTPGAS----PHHRRVPLSP-----LSLLAGPADAR-RSQQQLPKQFSP 457
L +P P + S PH R SP L+ P D R PK P
Sbjct: 368 RGSLSSPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPK--DP 425
Query: 458 TMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSV 517
+LSS P LS+ P P++ SL P PHT +SL P P S+
Sbjct: 426 HTRGSLSSPQD--PHTRGSLSS----PKDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSL 479
Query: 518 QSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLE--QFSMESPSASLVLDP 575
S Q P + +P P H ++S P G+L Q S S DP
Sbjct: 480 SSP--QDPHTRGSLSSPKDP----HTRRSLSCPQDPHTRGSLSCPQDPHTRGSLSCPQDP 533
Query: 576 --PGFSEGPGFLGGEGPMGGPQDPHT 599
G P L G + P+DPHT
Sbjct: 534 HTRGSLSSPQDLHTRGSLSSPKDPHT 559
Score = 31.6 bits (70), Expect = 2.6
Identities = 42/163 (25%), Positives = 59/163 (36%), Gaps = 24/163 (14%)
Query: 59 LAYTRSSHYGGSL--PNVNQIGSGLAEFQSP-LHSPLDSSRSTRHHGLVERVQRDP---R 112
L+ + H GSL P L+ Q P L S + G + +DP R
Sbjct: 407 LSSPQDPHTRGSLSSPKDPHTRGSLSSPQDPHTRGSLSSPKDPHTRGSLSS-PKDPHTRR 465
Query: 113 RMVSPLRRYTRHIDSSPYSP---AYLSPPPESSWRRTMAWGNFPAEKGQLF--------- 160
+ P +TR SSP P LS P + RR+++ P +G L
Sbjct: 466 SLSCPQDPHTRGSLSSPQDPHTRGSLSSPKDPHTRRSLSCPQDPHTRGSLSCPQDPHTRG 525
Query: 161 -----RLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILP 198
+ P SS LHT SP+D + P P + P
Sbjct: 526 SLSCPQDPHTRGSLSSPQDLHTRGSLSSPKDPHTPPRSPLVAP 568
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 57.8 bits (138), Expect = 3e-08
Identities = 82/315 (26%), Positives = 102/315 (32%), Gaps = 61/315 (19%)
Query: 254 PSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHT 313
P P QP P PP P PPP P P P++ A P++ T
Sbjct: 752 PVPQQPPPPPQQPPPPP-----PPQQQQQPPPPPPPPSMPQQAA-PAMKSSPPPFIATQV 805
Query: 314 MTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP---NLQASLSSPQPQLQGSHSHP 370
P+ P L S+ +P Q L PQP+L P
Sbjct: 806 -----------------------PVLEPQLPGSVFDPIGHFTQPILHLPQPELP-----P 837
Query: 371 SLPASSLARHVLPTTSLGHPSLSAPALSSS--SSSSSTSSPVLGAPSYPASTPGASPHHR 428
LP H P H +S PAL ++ S S+ P PA P SP
Sbjct: 838 HLPQP--PEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALT 895
Query: 429 RVPLSPLSLLAGPADARRSQQQLPKQFSPTMS-----PTLSSITQGVPLDTSKLSTDQ-- 481
+ PL P +A P ++ P +M L + PL S Q
Sbjct: 896 QTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPP 955
Query: 482 -RLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSH-----YGTPY 535
LPP P+ S L QP P Q P Q QPP R H + T
Sbjct: 956 PPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQ-------HQPPPRPVHLQPMQFSTHI 1008
Query: 536 PPGPSGHGQQSYHRP 550
P GQQ H P
Sbjct: 1009 QQPPPPQGQQPPHPP 1023
Score = 40.4 bits (93), Expect = 0.006
Identities = 83/335 (24%), Positives = 115/335 (34%), Gaps = 47/335 (14%)
Query: 256 PDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTP----LDPEETAYPSLSGGNSTSNLT 311
P +PA P + PA+ LP PP+ P L+ EE P L+ L
Sbjct: 881 PPKPARPPAVSPALTQTPLLPQ-------PPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQ 933
Query: 312 HTM-----THLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGS 366
T L S + P P P HPS+Q L PQP Q
Sbjct: 934 QLQKVQPPTPLLPSVKVQSQPPPPLP----PPPHPSVQQQLQQQPPPPPPPQPQPPPQQQ 989
Query: 367 HSHPSLPA----SSLARHVL--PTTSLGHPSLSAPALSSSSSSSSTSSPVL---GAPSYP 417
H P P + H+ P P P + V+ +P +
Sbjct: 990 HQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHH 1049
Query: 418 ASTPGASPHHRRVPLSPLSLLAGPADARRS--QQQLPKQFSPTMSPTL--SSITQGVPLD 473
S P ++ H R P SPL + + +S Q P+Q L +S+ Q PL
Sbjct: 1050 KSDPYSTGHLREAP-SPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLV 1108
Query: 474 TSK----LSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQP-GLPSQSCSVQSSGGQPPGRQ 528
K S R P+ SPSL P P P+S++ P LP + G+P R
Sbjct: 1109 VVKEEKIHSPIIRSEPF---SPSL-RPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRP 1164
Query: 529 SHYGTPYPPGPSGHGQQSYHR----PMSDFNLGNL 559
P P P Q+ + P D + N+
Sbjct: 1165 PEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNM 1199
Score = 30.8 bits (68), Expect = 4.4
Identities = 90/445 (20%), Positives = 138/445 (31%), Gaps = 65/445 (14%)
Query: 111 PRRMVSPLRRYTRHIDSSPYS--PAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNR 168
P + P+ +T+ I P P +L PPE S + + LP +R
Sbjct: 813 PGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSR 872
Query: 169 TSSDSAL------HTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLD 222
S+ +A ++P+ T P PP P + +L+ E P P +
Sbjct: 873 PSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQV--LLEDEEPPAPPLTSMQMQL 930
Query: 223 DKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLH 282
L+ S + +S P + P P + PP P H
Sbjct: 931 YLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQH 990
Query: 283 FPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPS 342
PPP P L P + + TH G P + PG P P
Sbjct: 991 QPPPRPVHLQPMQFS-------------THIQQP---PPPQGQQPPHPPPGQQPPPPQP- 1033
Query: 343 LQSSLSNPNLQASLSSPQPQLQGSHS---HPSLPASSLARHVLPTTSLGHPSLSAPALSS 399
+ PQ +Q HS H S P S+ P+ + H +P +S
Sbjct: 1034 --------------AKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIH----SPQMSQ 1075
Query: 400 SSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTM 459
S + S P AS + P L+ + S + FSP++
Sbjct: 1076 FQSLTHQSPPQQNVQPKKQELRAAS------VVQPQPLVVVKEEKIHSPIIRSEPFSPSL 1129
Query: 460 SPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQ-------PHTPKSLQQPG--- 509
P + + L + P P + P Q P K Q+P
Sbjct: 1130 RPEPPKHPESIKAPV-HLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPV 1188
Query: 510 LPSQSCSVQSSGGQPPGRQSHYGTP 534
P + +++ G Q H TP
Sbjct: 1189 APKKDLKIKNMGSWASLVQKHPTTP 1213
>gi|125858485 hypothetical protein LOC80209 isoform 2 [Homo sapiens]
Length = 922
Score = 57.0 bits (136), Expect = 6e-08
Identities = 111/421 (26%), Positives = 157/421 (37%), Gaps = 99/421 (23%)
Query: 237 SSSSRPRSCEVPGINIFP--------SPDQPANVPVLPPAMNTG---------------- 272
S+ P+ PG+ +FP S P +PV P
Sbjct: 500 SAIPTPQRTSTPGLALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASL 559
Query: 273 --GSLPDLTNLHFPP-------PLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGM 323
G P ++LH P+ +P + G + + N +H LG+S +
Sbjct: 560 LRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHSGNPSHGT--LGLSGTL 617
Query: 324 GLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSH--SHPSLPASSLARHV 381
G ++ S P S+ NP L + LSS L GS+ S SLP + +
Sbjct: 618 GRA--------YTSTSVPISLSACLNPAL-SGLSSLSTPLNGSNPLSSISLPPHGSSTPI 668
Query: 382 LPT-------TSL-------GHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHH 427
P TSL G+PSL+ P++S S +TSS A+T + PH
Sbjct: 669 APVFTALPSFTSLTNNFPLTGNPSLN-PSVSLPGSLIATSST--------AATSTSLPH- 718
Query: 428 RRVPLSPLSLLAG-PADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPY 486
P S ++L+G A A S P S T P+L S+TQG PL +S S P +
Sbjct: 719 ---PSSTAAVLSGLSASAPVSAAPFPLNLS-TAVPSLFSVTQG-PLSSSNPS----YPGF 769
Query: 487 PYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQS 546
S+ V P P P LQ P + + + P +P P P S
Sbjct: 770 SVSNTPSVTPALPSFP-GLQAPSTVAAVTPLPVAATAP--------SPAPVLPGFASAFS 820
Query: 547 YHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTFNHQNLT 606
S+FN + Q + S L G S PG L G G PQ+P + Q L
Sbjct: 821 -----SNFNSALVAQAGLSSG-----LQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQ 870
Query: 607 H 607
H
Sbjct: 871 H 871
Score = 56.6 bits (135), Expect = 7e-08
Identities = 99/376 (26%), Positives = 132/376 (35%), Gaps = 74/376 (19%)
Query: 187 TYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCE 246
T PG P PSR GI G P EE + K + A ++ S P S
Sbjct: 119 TIPGNPYPKGRPSRINGIFPGT--PLKKDGEECTNEGKGI-----AARILGPSKPPPSTY 171
Query: 247 VPGINI-FPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGN 305
P + +P P + + P A N G +P L N+ PPP P +P T
Sbjct: 172 NPHKPVPYPIPPCRPHATIAPSAYNNAGLVP-LANVIAPPPPPYTPNPVGTE-------- 222
Query: 306 STSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQG 365
+ LS+PS P + S+P QL
Sbjct: 223 -----------------------------NEDLSNPS------KPIQNQTFSTPASQLFS 247
Query: 366 SH-SHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVL-GAPSYPASTPGA 423
H S+PS PA++ P ++ HPS SA A S + +T PV G S TP
Sbjct: 248 PHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQP 307
Query: 424 SPHHRRVPLSPLSLLAGPADARRS--QQQLPKQFS-------PTMSPTLSSITQGVPLDT 474
S + V +P SL P + S +P FS P+ +PT ++ T G P
Sbjct: 308 SIPNPTVIRTP-SLPTAPVTSIHSTTTTPVPSIFSGLVSLPGPSATPTAATPTPG-PTPR 365
Query: 475 SKL-------STDQRLPPYPYSSPSLVLPTQPHTPKSLQQ--PGLPSQSCSVQSSGGQPP 525
S L ST P+S+ S T SL GLP P
Sbjct: 366 STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPT 425
Query: 526 GRQSHYGTPYPPGPSG 541
+ TP GP G
Sbjct: 426 PVIAGGSTPSVAGPLG 441
Score = 47.8 bits (112), Expect = 3e-05
Identities = 83/365 (22%), Positives = 136/365 (37%), Gaps = 41/365 (11%)
Query: 182 PSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSR 241
P+ PGPTP S L S E A +L P+ ++S+S
Sbjct: 353 PTAATPTPGPTPRSTLGS-------SEAFASTSAPFTSL--------PFSTSSSAASTSN 397
Query: 242 PRSCEVPGINI-FPSPDQPANVPVLPPA-MNTGGSLPDLTN-LHFPPPLPTPLDPEETAY 298
P S + + P P P + + P + GGS P + L PL + L T+
Sbjct: 398 PNSASLSSVFAGLPLPLPPTSQGLSNPTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSN 457
Query: 299 PS--LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPG-LHSPLSHPSLQSSLSNPNLQAS 355
+ ++ +S +T + L AP ++P + P+ Q + S P L
Sbjct: 458 DTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRT-STPGLALF 516
Query: 356 LSSPQPQLQGSHSHPSLPASS-LARHVLPTTSLG-------------HPSLSAPALSSSS 401
P P + + +LP S LA +TS+ HP S +SS+
Sbjct: 517 PGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTP 576
Query: 402 SSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSP 461
++++ + P+ P + P H P L+G + +P S ++P
Sbjct: 577 AATTLPVMIKTEPTSPTPSAFKGPSHSGNPSHGTLGLSGTLGRAYTSTSVPISLSACLNP 636
Query: 462 TLSSITQ-GVPLDTSKLSTDQRLPPYPYSSP----SLVLPTQPHTPKSLQQPGLPSQSCS 516
LS ++ PL+ S + LPP+ S+P LP+ + G PS + S
Sbjct: 637 ALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSLNPS 696
Query: 517 VQSSG 521
V G
Sbjct: 697 VSLPG 701
>gi|125656155 hypothetical protein LOC80209 isoform 1 [Homo sapiens]
Length = 944
Score = 57.0 bits (136), Expect = 6e-08
Identities = 111/421 (26%), Positives = 157/421 (37%), Gaps = 99/421 (23%)
Query: 237 SSSSRPRSCEVPGINIFP--------SPDQPANVPVLPPAMNTG---------------- 272
S+ P+ PG+ +FP S P +PV P
Sbjct: 522 SAIPTPQRTSTPGLALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASL 581
Query: 273 --GSLPDLTNLHFPP-------PLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGM 323
G P ++LH P+ +P + G + + N +H LG+S +
Sbjct: 582 LRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHSGNPSHGT--LGLSGTL 639
Query: 324 GLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSH--SHPSLPASSLARHV 381
G ++ S P S+ NP L + LSS L GS+ S SLP + +
Sbjct: 640 GRA--------YTSTSVPISLSACLNPAL-SGLSSLSTPLNGSNPLSSISLPPHGSSTPI 690
Query: 382 LPT-------TSL-------GHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHH 427
P TSL G+PSL+ P++S S +TSS A+T + PH
Sbjct: 691 APVFTALPSFTSLTNNFPLTGNPSLN-PSVSLPGSLIATSST--------AATSTSLPH- 740
Query: 428 RRVPLSPLSLLAG-PADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPY 486
P S ++L+G A A S P S T P+L S+TQG PL +S S P +
Sbjct: 741 ---PSSTAAVLSGLSASAPVSAAPFPLNLS-TAVPSLFSVTQG-PLSSSNPS----YPGF 791
Query: 487 PYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPGPSGHGQQS 546
S+ V P P P LQ P + + + P +P P P S
Sbjct: 792 SVSNTPSVTPALPSFP-GLQAPSTVAAVTPLPVAATAP--------SPAPVLPGFASAFS 842
Query: 547 YHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPMGGPQDPHTFNHQNLT 606
S+FN + Q + S L G S PG L G G PQ+P + Q L
Sbjct: 843 -----SNFNSALVAQAGLSSG-----LQAAGSSVFPGLLSLPGIPGFPQNPSQSSLQELQ 892
Query: 607 H 607
H
Sbjct: 893 H 893
Score = 56.6 bits (135), Expect = 7e-08
Identities = 99/376 (26%), Positives = 132/376 (35%), Gaps = 74/376 (19%)
Query: 187 TYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCE 246
T PG P PSR GI G P EE + K + A ++ S P S
Sbjct: 141 TIPGNPYPKGRPSRINGIFPGT--PLKKDGEECTNEGKGI-----AARILGPSKPPPSTY 193
Query: 247 VPGINI-FPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGN 305
P + +P P + + P A N G +P L N+ PPP P +P T
Sbjct: 194 NPHKPVPYPIPPCRPHATIAPSAYNNAGLVP-LANVIAPPPPPYTPNPVGTE-------- 244
Query: 306 STSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQG 365
+ LS+PS P + S+P QL
Sbjct: 245 -----------------------------NEDLSNPS------KPIQNQTFSTPASQLFS 269
Query: 366 SH-SHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVL-GAPSYPASTPGA 423
H S+PS PA++ P ++ HPS SA A S + +T PV G S TP
Sbjct: 270 PHGSNPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQP 329
Query: 424 SPHHRRVPLSPLSLLAGPADARRS--QQQLPKQFS-------PTMSPTLSSITQGVPLDT 474
S + V +P SL P + S +P FS P+ +PT ++ T G P
Sbjct: 330 SIPNPTVIRTP-SLPTAPVTSIHSTTTTPVPSIFSGLVSLPGPSATPTAATPTPG-PTPR 387
Query: 475 SKL-------STDQRLPPYPYSSPSLVLPTQPHTPKSLQQ--PGLPSQSCSVQSSGGQPP 525
S L ST P+S+ S T SL GLP P
Sbjct: 388 STLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPT 447
Query: 526 GRQSHYGTPYPPGPSG 541
+ TP GP G
Sbjct: 448 PVIAGGSTPSVAGPLG 463
Score = 47.8 bits (112), Expect = 3e-05
Identities = 83/365 (22%), Positives = 136/365 (37%), Gaps = 41/365 (11%)
Query: 182 PSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSR 241
P+ PGPTP S L S E A +L P+ ++S+S
Sbjct: 375 PTAATPTPGPTPRSTLGS-------SEAFASTSAPFTSL--------PFSTSSSAASTSN 419
Query: 242 PRSCEVPGINI-FPSPDQPANVPVLPPA-MNTGGSLPDLTN-LHFPPPLPTPLDPEETAY 298
P S + + P P P + + P + GGS P + L PL + L T+
Sbjct: 420 PNSASLSSVFAGLPLPLPPTSQGLSNPTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSN 479
Query: 299 PS--LSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPG-LHSPLSHPSLQSSLSNPNLQAS 355
+ ++ +S +T + L AP ++P + P+ Q + S P L
Sbjct: 480 DTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRT-STPGLALF 538
Query: 356 LSSPQPQLQGSHSHPSLPASS-LARHVLPTTSLG-------------HPSLSAPALSSSS 401
P P + + +LP S LA +TS+ HP S +SS+
Sbjct: 539 PGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTP 598
Query: 402 SSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSP 461
++++ + P+ P + P H P L+G + +P S ++P
Sbjct: 599 AATTLPVMIKTEPTSPTPSAFKGPSHSGNPSHGTLGLSGTLGRAYTSTSVPISLSACLNP 658
Query: 462 TLSSITQ-GVPLDTSKLSTDQRLPPYPYSSP----SLVLPTQPHTPKSLQQPGLPSQSCS 516
LS ++ PL+ S + LPP+ S+P LP+ + G PS + S
Sbjct: 659 ALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSLNPS 718
Query: 517 VQSSG 521
V G
Sbjct: 719 VSLPG 723
>gi|40807452 peroxisome proliferator-activated receptor gamma,
coactivator-related 1 [Homo sapiens]
Length = 1664
Score = 55.8 bits (133), Expect = 1e-07
Identities = 107/471 (22%), Positives = 157/471 (33%), Gaps = 100/471 (21%)
Query: 153 PAEKGQLFRLPSALNRTSSD------SALHTSVMNPSPQDTYPGPTPPSILPSRRGGILD 206
PA++G L P + ++ S + ++ +P P D+ P+ G +L
Sbjct: 549 PAKEGPLDLYPKLADTIQTNPIPTHLSLVDSAQASPMPVDSVEAD------PTAVGPVLA 602
Query: 207 GEMDPKVPAIEENLLDDKHLLKPWDAKK------LSSSSSR-----PRSCEVPGINIFPS 255
G + P P + + L++P A+ L+ S++ P S +P ++ PS
Sbjct: 603 GPV-PVDPGLVDLASTSSELVEPLPAEPVLINPVLADSAAVDPAVVPISDNLPPVDAVPS 661
Query: 256 PDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHT-- 313
P ++ ++ P N DLT + P DP A S GG++ L +
Sbjct: 662 GPAPVDLALVDPVPN------DLTPVDPVLVKSRPTDPRRGAVSSALGGSAPQLLVESES 715
Query: 314 --------------MTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSP 359
+ L I G P PLS + + SP
Sbjct: 716 LDPPKTIIPEVKEVVDSLKIESGTSATTHEARP---RPLSLSEYRRRRQQRQAETEERSP 772
Query: 360 QPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSST-------SSPVLG 412
QP + PSLP + +P + AL S + SP
Sbjct: 773 QPP---TGKWPSLPETPTGLADIPCLVIPPAPAKKTALQRSPETPLEICLVPVGPSPASP 829
Query: 413 APSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPL 472
+P P S P AS +VP + LLA P+ +S SP + PT S++ +P
Sbjct: 830 SPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQS-------VSPAV-PTPPSMSAALPF 881
Query: 473 DTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPG-LPSQSC--SVQSSG-------- 521
L LPP P PSL L P P LPS C V SG
Sbjct: 882 PAGGLGMPPSLPPPPLQPPSLPLSMGPVLPDPFTHYAPLPSWPCYPHVSPSGYPCLPPPP 941
Query: 522 ----------------------GQPPGRQSHYGTPYPPGPSGHGQQSYHRP 550
PP S Y + GP G G H P
Sbjct: 942 TVPLVSGTPGAYAVPPTCSVPWAPPPAPVSPYSSTCTYGPLGWGPGPQHAP 992
Score = 37.7 bits (86), Expect = 0.036
Identities = 96/432 (22%), Positives = 151/432 (34%), Gaps = 91/432 (21%)
Query: 69 GSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHIDSS 128
G P++ + +GLA+ + P + ++ +QR P +PL + S
Sbjct: 777 GKWPSLPETPTGLADIPCLVIPPAPAKKTA--------LQRSPE---TPLEICLVPVGPS 825
Query: 129 PYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTY 188
P SP+ PP S + P+++ L PS P Q
Sbjct: 826 PASPS--PEPPVSKPVASSPTEQVPSQEMPLLARPS-----------------PPVQSVS 866
Query: 189 PG-PTPPSI---LPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRP-- 242
P PTPPS+ LP GG+ M P +P L+P + LS P
Sbjct: 867 PAVPTPPSMSAALPFPAGGL---GMPPSLPPPP---------LQP-PSLPLSMGPVLPDP 913
Query: 243 --RSCEVPGINIFPSPDQPANVPVLPP------AMNTGGS--LPDLTNLHFPPPLPTPLD 292
+P +P P+ P LPP T G+ +P ++ + PP P P+
Sbjct: 914 FTHYAPLPSWPCYPHVS-PSGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWAPP-PAPVS 971
Query: 293 PEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNL 352
P + T T+ +G GPG S + P L P
Sbjct: 972 PYSS----------------TCTY----GPLGWGPGPQHAPFWSTVPPPPL------PPA 1005
Query: 353 QASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLG 412
+ PQP+++ + P + L + P SLG P AP + + P
Sbjct: 1006 SIGRAVPQPKMESRGTPAGPPENVLPLSMAPPLSLGLPGHGAPQ-TEPTKVEVKPVPASP 1064
Query: 413 APSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPL 472
P + S SP + + + A + ++ P P L + T+ VP
Sbjct: 1065 HPKHKVSALVQSPQMKALACVSAEGVTVEEPASERLKPETQETRPREKPPLPA-TKAVP- 1122
Query: 473 DTSKLSTDQRLP 484
T + ST +LP
Sbjct: 1123 -TPRQSTVPKLP 1133
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 55.5 bits (132), Expect = 2e-07
Identities = 112/434 (25%), Positives = 158/434 (36%), Gaps = 33/434 (7%)
Query: 138 PPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDT-YPGPTPPSI 196
P +W ++ G P G PSA + S S ++ +P+P PGP+ P I
Sbjct: 1526 PAYGAWSPSVGSGMTPGAAGFS---PSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYI 1582
Query: 197 LPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFP-- 254
PS GG + P PA E P + S S S N P
Sbjct: 1583 -PSP-GGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTS 1640
Query: 255 ---SPDQPANVPVLPPAMNTGGSLPDLTNLHFPP-----PLPTPLDPEETAYPSLSGGNS 306
SP P+ P P T S + + P P P +Y S S
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1700
Query: 307 TSNLTHTMTHLGIS-RGMGLGPGYDAPGLHSPLSHPSLQS-SLSNPNLQASLSSPQPQLQ 364
++ +++ T S P + SP P+ S S ++PN + + P
Sbjct: 1701 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP 1760
Query: 365 G-SHSHPSL-PASSLARHVLPTTSLGHPSLS--APALSSSSSSSSTSSP--VLGAPSYPA 418
S + PS P S P S PS S +P+ S +S S S SSP +P+Y
Sbjct: 1761 SYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTP 1820
Query: 419 STPGASPHHRRV-PLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKL 477
S+P SP P SP P+ + S + P SP SPT + P +
Sbjct: 1821 SSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPT--SPKYSPTSPKYSPTSPKYSPTS 1878
Query: 478 ST-DQRLPPYPYSSPSLVLPTQP-HTPKSLQ-QPGLPSQSCSVQSSGGQPP--GRQSHYG 532
T P Y +SP+ PT P +TP S + P P+ S + P S G
Sbjct: 1879 PTYSPTTPKYSPTSPT-YSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKG 1937
Query: 533 TPYPPGPSGHGQQS 546
+ Y P G+ S
Sbjct: 1938 STYSPTSPGYSPTS 1951
Score = 50.1 bits (118), Expect = 7e-06
Identities = 90/339 (26%), Positives = 134/339 (39%), Gaps = 37/339 (10%)
Query: 259 PANVPVLPPAMNTG---GSLPDLTNLHFPPPLPTPLDPEET-AY----PSLSGGNSTSNL 310
P N+P L A TG GS P + + P TP + T AY PS+ G +
Sbjct: 1487 PTNIPGLGAAGPTGMFFGSAP--SPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAA 1544
Query: 311 THTMTHLGISRGMGLGPGYD--------APGLHSPLSH--PSLQSSLSNPNLQASLSSPQ 360
+ + S G PGY +PG P S PS ++S P+ + + +
Sbjct: 1545 GFSPS--AASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMS-PSYSPTSPAYE 1601
Query: 361 PQLQGSHSHPSLPASSLARHVLPTTSLGHP-----SLSAPALSSSSSSSSTSSPVLG--A 413
P+ G ++ S S + PT+ P S ++P+ S +S S S +SP +
Sbjct: 1602 PRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTS 1661
Query: 414 PSYPASTPGASPHHRRV-PLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVP- 471
PSY ++P SP P SP P+ + S P SP+ SPT S + P
Sbjct: 1662 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT--SPSYSPTSPSYSPTSPS 1719
Query: 472 LDTSKLSTDQRLPPYPYSSPSLVLPTQP-HTPKSLQ-QPGLPSQSCSVQSSGGQPPGRQS 529
+ S P Y +SPS PT P ++P S P PS S + S P
Sbjct: 1720 YSPTSPSYSPTSPSYSPTSPS-YSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTP 1778
Query: 530 HYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPS 568
P PS + P S + +++ +SP+
Sbjct: 1779 TSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPT 1817
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.5 bits (132), Expect = 2e-07
Identities = 120/527 (22%), Positives = 180/527 (34%), Gaps = 56/527 (10%)
Query: 54 AQKLRLAYTRSSHYGGSLPNVNQIGSGLAEFQSP-LHSPLDSSRSTRHHGLVERVQRDPR 112
AQ + T + G + P Q+G+ Q P L SP + T+ + P
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 113 RMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSD 172
+ P + T + P P P P + P ++ + PS ++
Sbjct: 452 QQAGPGK--TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 173 SALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDA 232
PSPQ PG T P PS++ G PA K + +
Sbjct: 510 PPQQPGPAKPSPQQ--PGSTKP---PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 233 KKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLD 292
K L + P S + P PS P + P NT L LH P
Sbjct: 565 KPLQPPTVSP-SAKQP-----PSQGLPKTIC---PLCNTTELL-----LHVPEKANFNTC 610
Query: 293 PE-ETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYD-APGLHSPLSHPSLQSSLSNP 350
E +T SL G N +LT L ++ M G D AP SP P L+++
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTT 668
Query: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410
S SSPQPQ Q S + P L++ P P + P L S S+ + P
Sbjct: 669 TSAVSKSSPQPQ-QTSPKKDAAPKQDLSK--APEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 411 LGAPSYPA--STPGASPHHRRVPLS-----------PLSLLAGPADAR--------RSQQ 449
+ S PA P + P++ P + L + A + Q
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 450 QLPKQFSPTMSPTLSSITQGVPLDTSKLST-DQRLPPYPYSSPSLVLPTQPHTPKSLQQP 508
Q ++ +P + + +Q P K+S D + P P S ++ P + Q+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 509 GLPSQSCSVQSSGG-----QPPGRQSHYGTPYPPGPSGHGQQSYHRP 550
P Q +P + G+P PPGP Q+ P
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Score = 43.5 bits (101), Expect = 7e-04
Identities = 78/301 (25%), Positives = 99/301 (32%), Gaps = 32/301 (10%)
Query: 255 SPDQPANVPVLPPAMNTGGSLPDLTNL----HFPPPLPTPLDPEETAYPSLSGGNSTSNL 310
S QP + PP TG + T H PL +T + G S
Sbjct: 240 SSQQPEKIKSQPPG--TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 311 THTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQAS-LSSPQPQLQGSHSH 369
+ + I + P PG H Q + P Q S L+ P Q G+
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPG------HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 370 PSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVL-----GAPSYPASTPG-A 423
P P + P LG A S SS P G PA PG A
Sbjct: 352 PVQPPGTTKP---PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 424 SPHHRRV----PLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLST 479
P ++V PL+ L PA A + +Q P P Q P TS T
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA----QQAGPGKTSAQQT 464
Query: 480 DQRLPPYPYSSPSLVLPTQPHTPKSL-QQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPG 538
PP P+ P QP K QQPG ++ S Q +PP +Q P P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523
Query: 539 P 539
P
Sbjct: 524 P 524
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/315 (24%), Positives = 106/315 (33%), Gaps = 54/315 (17%)
Query: 235 LSSSSSRPRSCE---VPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHF---PPPLP 288
L +SRP++ + V G ++ PS P+ P+ P T G P H P P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP---TPGKPPAQQPGHEKSQPGPAK 330
Query: 289 TPLDPEETAYPSLSGGNSTSNLTHTMTHL-GISRGMGLGPGYDAPGLH--SPLSHPSLQS 345
P P S LT + G + PG P P P+ Q+
Sbjct: 331 PPAQP--------------SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 346 SLSNPNLQASLSSPQPQLQGSHSHPSL---PASSLARHVLPTTSLG-------HPSLSAP 395
P SS QP + P + PA PT +G P L +P
Sbjct: 377 GSEKP------SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 396 ALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQF 455
A + + + P G + PG + + P P S L GPA + QQ
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA--KPPPQQPGPAK 488
Query: 456 SPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPK-SLQQPGLPSQS 514
P P + P T PP P+ P QP + K QQPG S
Sbjct: 489 PPPQQPGSAKPPSQQPGSTK--------PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
Query: 515 CSVQSSGGQPPGRQS 529
Q S +P +QS
Sbjct: 541 AQ-QPSPAKPSAQQS 554
Score = 40.8 bits (94), Expect = 0.004
Identities = 84/360 (23%), Positives = 125/360 (34%), Gaps = 47/360 (13%)
Query: 153 PAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPK 212
P+ + LP+ S+L S P P P P PP P L PK
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP--PPPPPPPLPPPTSPK 2434
Query: 213 VPAIEENLLDDKHLLKP----WDAKKLSSSSSRPRSCEVPGINIF-----PSPDQPANVP 263
+ + L + +DA +++ RS +P I P P +P+++P
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP 2494
Query: 264 V-LPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRG 322
L S P + P LPT +P +G + TS++T +
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV------- 2547
Query: 323 MGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVL 382
Y P SPLS S+ S+P SL+ + S P P S A +
Sbjct: 2548 --TSADYKLPSPTSPLSP---HSNKSSPRFSKSLTETYVVIT-LPSEPGTPTDSSASQAI 2601
Query: 383 PTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPA 442
+ LG PS L S S PV P +S + + + A P
Sbjct: 2602 TSWPLGSPSKD---LVSVEPVFSVVPPVTA-----VEIPISSEQTFYISGALQTFSATPV 2653
Query: 443 DARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKL---STDQRLPPYPYSSPSLVLPTQP 499
A S Q P +S+TQ + + SK +T P SS S+ +P +P
Sbjct: 2654 TAPSSFQAAP-----------TSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 31.2 bits (69), Expect = 3.4
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 461 PTLSSITQGV--PLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQS 514
PT G+ P + Q +PP + LV PT P+T P LP+Q+
Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
Score = 30.0 bits (66), Expect = 7.5
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 460 SPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQS 519
SP+ ++I G+ D S+LS ++R S + LP P + + P + + S
Sbjct: 31 SPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSS 90
Query: 520 SGGQPPGRQSHYGTPYPPGPS 540
+ GR G P PG S
Sbjct: 91 HPPKQSGRPPDPGRPAQPGLS 111
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.5 bits (132), Expect = 2e-07
Identities = 120/527 (22%), Positives = 180/527 (34%), Gaps = 56/527 (10%)
Query: 54 AQKLRLAYTRSSHYGGSLPNVNQIGSGLAEFQSP-LHSPLDSSRSTRHHGLVERVQRDPR 112
AQ + T + G + P Q+G+ Q P L SP + T+ + P
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451
Query: 113 RMVSPLRRYTRHIDSSPYSPAYLSPPPESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSD 172
+ P + T + P P P P + P ++ + PS ++
Sbjct: 452 QQAGPGK--TSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKP 509
Query: 173 SALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDA 232
PSPQ PG T P PS++ G PA K + +
Sbjct: 510 PPQQPGPAKPSPQQ--PGSTKP---PSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 233 KKLSSSSSRPRSCEVPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLD 292
K L + P S + P PS P + P NT L LH P
Sbjct: 565 KPLQPPTVSP-SAKQP-----PSQGLPKTIC---PLCNTTELL-----LHVPEKANFNTC 610
Query: 293 PE-ETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYD-APGLHSPLSHPSLQSSLSNP 350
E +T SL G N +LT L ++ M G D AP SP P L+++
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLKTAPVTT 668
Query: 351 NLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV 410
S SSPQPQ Q S + P L++ P P + P L S S+ + P
Sbjct: 669 TSAVSKSSPQPQ-QTSPKKDAAPKQDLSK--APEPKKPPPLVKQPTLHGSPSAKAKQPPE 725
Query: 411 LGAPSYPA--STPGASPHHRRVPLS-----------PLSLLAGPADAR--------RSQQ 449
+ S PA P + P++ P + L + A + Q
Sbjct: 726 ADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQS 785
Query: 450 QLPKQFSPTMSPTLSSITQGVPLDTSKLST-DQRLPPYPYSSPSLVLPTQPHTPKSLQQP 508
Q ++ +P + + +Q P K+S D + P P S ++ P + Q+
Sbjct: 786 QAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQ 845
Query: 509 GLPSQSCSVQSSGG-----QPPGRQSHYGTPYPPGPSGHGQQSYHRP 550
P Q +P + G+P PPGP Q+ P
Sbjct: 846 VDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Score = 43.5 bits (101), Expect = 7e-04
Identities = 78/301 (25%), Positives = 99/301 (32%), Gaps = 32/301 (10%)
Query: 255 SPDQPANVPVLPPAMNTGGSLPDLTNL----HFPPPLPTPLDPEETAYPSLSGGNSTSNL 310
S QP + PP TG + T H PL +T + G S
Sbjct: 240 SSQQPEKIKSQPPG--TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297
Query: 311 THTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQAS-LSSPQPQLQGSHSH 369
+ + I + P PG H Q + P Q S L+ P Q G+
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPG------HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKP 351
Query: 370 PSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVL-----GAPSYPASTPG-A 423
P P + P LG A S SS P G PA PG A
Sbjct: 352 PVQPPGTTKP---PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPA 408
Query: 424 SPHHRRV----PLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKLST 479
P ++V PL+ L PA A + +Q P P Q P TS T
Sbjct: 409 KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA----QQAGPGKTSAQQT 464
Query: 480 DQRLPPYPYSSPSLVLPTQPHTPKSL-QQPGLPSQSCSVQSSGGQPPGRQSHYGTPYPPG 538
PP P+ P QP K QQPG ++ S Q +PP +Q P P
Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG-SAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523
Query: 539 P 539
P
Sbjct: 524 P 524
Score = 42.0 bits (97), Expect = 0.002
Identities = 78/315 (24%), Positives = 106/315 (33%), Gaps = 54/315 (17%)
Query: 235 LSSSSSRPRSCE---VPGINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHF---PPPLP 288
L +SRP++ + V G ++ PS P+ P+ P T G P H P P
Sbjct: 274 LQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP---TPGKPPAQQPGHEKSQPGPAK 330
Query: 289 TPLDPEETAYPSLSGGNSTSNLTHTMTHL-GISRGMGLGPGYDAPGLH--SPLSHPSLQS 345
P P S LT + G + PG P P P+ Q+
Sbjct: 331 PPAQP--------------SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT 376
Query: 346 SLSNPNLQASLSSPQPQLQGSHSHPSL---PASSLARHVLPTTSLG-------HPSLSAP 395
P SS QP + P + PA PT +G P L +P
Sbjct: 377 GSEKP------SSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 396 ALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQF 455
A + + + P G + PG + + P P S L GPA + QQ
Sbjct: 431 AKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPA--KPPPQQPGPAK 488
Query: 456 SPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPK-SLQQPGLPSQS 514
P P + P T PP P+ P QP + K QQPG S
Sbjct: 489 PPPQQPGSAKPPSQQPGSTK--------PPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPS 540
Query: 515 CSVQSSGGQPPGRQS 529
Q S +P +QS
Sbjct: 541 AQ-QPSPAKPSAQQS 554
Score = 40.8 bits (94), Expect = 0.004
Identities = 84/360 (23%), Positives = 125/360 (34%), Gaps = 47/360 (13%)
Query: 153 PAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPK 212
P+ + LP+ S+L S P P P P PP P L PK
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPP--PPPPPPPLPPPTSPK 2434
Query: 213 VPAIEENLLDDKHLLKP----WDAKKLSSSSSRPRSCEVPGINIF-----PSPDQPANVP 263
+ + L + +DA +++ RS +P I P P +P+++P
Sbjct: 2435 PTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIP 2494
Query: 264 V-LPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRG 322
L S P + P LPT +P +G + TS++T +
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLV------- 2547
Query: 323 MGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVL 382
Y P SPLS S+ S+P SL+ + S P P S A +
Sbjct: 2548 --TSADYKLPSPTSPLSP---HSNKSSPRFSKSLTETYVVIT-LPSEPGTPTDSSASQAI 2601
Query: 383 PTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPA 442
+ LG PS L S S PV P +S + + + A P
Sbjct: 2602 TSWPLGSPSKD---LVSVEPVFSVVPPVTA-----VEIPISSEQTFYISGALQTFSATPV 2653
Query: 443 DARRSQQQLPKQFSPTMSPTLSSITQGVPLDTSKL---STDQRLPPYPYSSPSLVLPTQP 499
A S Q P +S+TQ + + SK +T P SS S+ +P +P
Sbjct: 2654 TAPSSFQAAP-----------TSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEP 2702
Score = 32.3 bits (72), Expect = 1.5
Identities = 34/117 (29%), Positives = 44/117 (37%), Gaps = 11/117 (9%)
Query: 353 QASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLG 412
Q+S SP+P + S SH P S V PT H S+P S SSS S
Sbjct: 4841 QSSQQSPKPSVIKSRSHGIFPDPSKDMQV-PTIEKSH---SSPGSSKSSSEGHLRS---H 4893
Query: 413 APSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQG 469
PS S + H L A+A Q ++ P P SS++ G
Sbjct: 4894 GPSRSQSKTSVTQTH----LEDAGAAIAAAEAAVQQLRIQPTKPPNHRPAESSVSTG 4946
Score = 31.2 bits (69), Expect = 3.4
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 461 PTLSSITQGV--PLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQS 514
PT G+ P + Q +PP + LV PT P+T P LP+Q+
Sbjct: 3844 PTRIESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQA 3899
Score = 30.0 bits (66), Expect = 7.5
Identities = 22/81 (27%), Positives = 35/81 (43%)
Query: 460 SPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQS 519
SP+ ++I G+ D S+LS ++R S + LP P + + P + + S
Sbjct: 31 SPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSS 90
Query: 520 SGGQPPGRQSHYGTPYPPGPS 540
+ GR G P PG S
Sbjct: 91 HPPKQSGRPPDPGRPAQPGLS 111
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 55.5 bits (132), Expect = 2e-07
Identities = 97/403 (24%), Positives = 137/403 (33%), Gaps = 62/403 (15%)
Query: 81 LAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHIDSSPY--SPAYLSPP 138
L E + + +S S GL + P+ + + H + P P++L P
Sbjct: 822 LDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPG 881
Query: 139 PESSWRRTMAWGNFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPGP---TPP- 194
P R+ AE + + P A+ + S S + + P P + P P TPP
Sbjct: 882 PGLMLRQKSIGA---AEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPV 938
Query: 195 -----SILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPG 249
+ PS RGG + +PA D P D + S S S +P
Sbjct: 939 PSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGP---SPPDTRVGSREKSLYHSGPLPP 995
Query: 250 INIFPS--------PDQPANV---PVLPPAMNTGGS------------LPDLTNLHFPPP 286
+ P P QP + P PP M TGGS P L P
Sbjct: 996 AHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGP 1055
Query: 287 LPTPLDPEETAYPSLSGGNSTSN---LTHTMTHLGISRGMGLGPGYDAPGLHSPL----- 338
PTP P + + S GG +S L + + P G PL
Sbjct: 1056 SPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTK 1115
Query: 339 --SHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHV-LPTTSLGHPSLSAP 395
P L S +SPQP P++ A S + +PT + PS S+
Sbjct: 1116 VEGEPQKGGGLPPAPSPTSPASPQPP-------PAVAAPSEKNSIPIPTIIIKAPSTSSS 1168
Query: 396 ALSSSSSSSSTSSPV----LGAPSYPASTPGASPHHRRVPLSP 434
SS SS+ P G S+P +P VP SP
Sbjct: 1169 GRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSP 1211
Score = 45.1 bits (105), Expect = 2e-04
Identities = 90/374 (24%), Positives = 129/374 (34%), Gaps = 71/374 (18%)
Query: 189 PGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVP 248
P PS LP G +L + A E DD+ L P A K S S S P S ++P
Sbjct: 870 PSYERPSFLPPGPGLML---RQKSIGAAE----DDRPYLAP-PAMKFSRSLSVPGSEDIP 921
Query: 249 GINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLHFPP----PLP--TPLDPEETAYPSLS 302
P+ P + P +P + +G P F P PLP +P + + P
Sbjct: 922 PPPTTSPPEPPYSTPPVPSS--SGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTR 979
Query: 303 GGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNPNLQASLSSPQPQ 362
G+ +L H+ G P H P H + P PQ
Sbjct: 980 VGSREKSLYHS--------------GPLPPAHHHPPHHHHHHA-------------PPPQ 1012
Query: 363 LQGSHSHPSLP----ASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPA 418
H+HP P P +LG P+L + +P +PS+
Sbjct: 1013 PHHHHAHPPHPPEMETGGSPDDPPPRLALG----PQPSLRGWRGGGPSPTPGAPSPSHHG 1068
Query: 419 STPGAS-----PHHRRVPLSPLSLLAG---PADARRSQQ-QLPKQFSPTMSPTLSSITQG 469
S G P R L P + A PA + R ++ L KQ P
Sbjct: 1069 SAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPP 1128
Query: 470 VPLDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQS 529
P TS P P P++ P++ + S+ P + ++ S SSG G +
Sbjct: 1129 APSPTS--------PASPQPPPAVAAPSEKN---SIPIPTIIIKAPSTSSSGRSSQGSST 1177
Query: 530 HYGTPYPPGPSGHG 543
P P P+G G
Sbjct: 1178 EAEPPTQPEPTGGG 1191
Score = 35.4 bits (80), Expect = 0.18
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 26/182 (14%)
Query: 284 PPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGL-------GPGYDAPGLHS 336
PPPLP PL + + + + S L+ + G S G G G H
Sbjct: 1848 PPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHG 1907
Query: 337 PLSH-PSLQSSLSNPNLQ-----ASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHP 390
S+ P SSL L + LS P L + P LP V PT +
Sbjct: 1908 GASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPG 1967
Query: 391 SLSAPALSSSSSSSSTSS-------PVL-GAPS---YPASTPGASPHHRRVPLSPLSLLA 439
+ S A SSS+S+ P+L APS PAS SP R P S L +
Sbjct: 1968 ATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPR--PSSLPILPS 2025
Query: 440 GP 441
GP
Sbjct: 2026 GP 2027
Score = 32.3 bits (72), Expect = 1.5
Identities = 70/289 (24%), Positives = 95/289 (32%), Gaps = 45/289 (15%)
Query: 284 PPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHL-GIS------RGMGLGPGYDAPGLHS 336
P P P P P A P +S + L G S R +G G +
Sbjct: 1374 PQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSL 1433
Query: 337 PLSHPSLQSSLSN------PN-----LQASLSSPQPQLQGSHSHPSLPASSLARHVLPTT 385
P S P+ + SL + P LQ P P S S R L
Sbjct: 1434 PASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVR 1493
Query: 386 SLGHPSLSAPALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADAR 445
L + AP ++S S P + PS S P + R + L LL P A
Sbjct: 1494 FLENCQPRAP-VTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAP 1552
Query: 446 RSQQQ-----------LPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLV 494
+ P +FS + S +T G P LP P +P+
Sbjct: 1553 SVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPP---------HPLPDTP--APATP 1601
Query: 495 LPTQPHTPKSLQQPGLPSQSCSVQSSGGQ----PPGRQSHYGTPYPPGP 539
LP P + P L S + S+ S + G + G P+PPGP
Sbjct: 1602 LPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP 1650
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 55.5 bits (132), Expect = 2e-07
Identities = 101/440 (22%), Positives = 150/440 (34%), Gaps = 96/440 (21%)
Query: 128 SPYSPAYLSPPPESSWRRTMAWGNFPAEKGQ----LFRLPSALNRTSSDSALHTSVMNPS 183
+P PA P P+ S P KG PS + + +S P+
Sbjct: 1309 APTPPAATPPSPKGS-------PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 184 PQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPR 243
+ GPTPP+ PS +GG M P P K + P+
Sbjct: 1362 TPSSKEGPTPPAATPSHKGG---PAMTPPSP-------------------KRGPAIPSPK 1399
Query: 244 SCEVPGINIFPSPDQPANVPVLP------PAMNTGGSLPDLTNLHFPPPLPTPLDPEET- 296
P PA +P+ P P G + P +L PP TP+ ++
Sbjct: 1400 G----------DPTSPAVIPLSPKKAPATPVTREGAATPSKGDL--TPPAVTPVSLKKAP 1447
Query: 297 AYPSLSGGNSTSNLTHTMTHLGISRGMGLGP--GYDAPGLHSPLSHPSLQSSLSNPNLQA 354
A + GG +T + T ++ P SP P+ + + P L A
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507
Query: 355 SL-SSPQ--PQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPV- 410
+ SSP+ P S P P ++L P T +L PA++ S + + P
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 411 LGAPSYP-----ASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSS 465
AP+ P +S P +P + SP LL PA SP +PT +
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSP---------SPKEAPTPPA 1618
Query: 466 ITQGVPLDTSKLSTDQRLPPYPYSSPSLVLP-----TQPHTPKSLQQPGLPSQSCSVQSS 520
+T PP P P+ P + P TP SL+ S + +
Sbjct: 1619 VT----------------PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMG 1662
Query: 521 GGQPPGRQSHYGTPYPPGPS 540
P Q+ G P GP+
Sbjct: 1663 ATVP---QASKGLPAKKGPT 1679
Score = 55.1 bits (131), Expect = 2e-07
Identities = 104/428 (24%), Positives = 144/428 (33%), Gaps = 65/428 (15%)
Query: 182 PSPQDTYPGPTPPSILP-SRRGGILDGEMD--PKVPAIEENLLDDKHLLKPWDAKKLSSS 238
PSP+ PTPP+ P S +GG P PA+ P K ++
Sbjct: 980 PSPKGA---PTPPAATPPSPKGGPATPSPKGAPTPPAVT-----------PPSPKGSPAA 1025
Query: 239 SSRPRSCEVPGINIFPSPD-QPANVPVLPPAMNT-GGSLPDLTNLHFPPPLPTPLDPEET 296
+ P+ P PSP PA P+ A T +LP P L P
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 297 AYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPSLQSSLSNP-----N 351
PS GG +T + +G + P P L+ P + + + P +
Sbjct: 1086 TPPSPKGGPATPS----------PKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS 1135
Query: 352 LQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSSSSSTSSPVL 411
+ L++P P+ G+ + P+ S + G P+ A S +T SP
Sbjct: 1136 PKGGLATPPPK--GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK- 1192
Query: 412 GAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPTLSSITQGVP 471
GAP+ PA+TP SP SP PA S PK T SP +G P
Sbjct: 1193 GAPTTPAATP-PSPKGGLATPSPKGAPTTPAATPPS----PKGGLATPSP------KGAP 1241
Query: 472 LDTSKLSTDQRLPPYPYSSPSLVLPTQPHTPKSLQQPGLPSQSCSVQSSGGQPPGRQSHY 531
+T PP P P+ P TP + P L + G P
Sbjct: 1242 ------TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP------ 1289
Query: 532 GTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPPGFSEGPGFLGGEGPM 591
PP P G S + + SP S PP + P + P
Sbjct: 1290 AVVTPPSPKGGPATSPPK-----GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Query: 592 GGPQDPHT 599
G P P T
Sbjct: 1345 GTPTLPAT 1352
Score = 50.8 bits (120), Expect = 4e-06
Identities = 110/470 (23%), Positives = 161/470 (34%), Gaps = 129/470 (27%)
Query: 211 PKVPAIEENLLDDKHLLKPWDAKKLSSSSSRP----RSCEVPGINIFPSPDQPANVPVLP 266
P++P E L K L +P K +SS + P S V + + PD P+L
Sbjct: 580 PEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG--PLLK 637
Query: 267 PAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLG 326
++ T P PL+ + A + + TS T T +
Sbjct: 638 SSLIT------------PTVAAFPLESADPAGVAPTTAKGTSTYTTTAS----------- 674
Query: 327 PGYDAPGLHSPLSHPSLQSSLSNPNLQASLS-------SPQ------------PQLQGSH 367
P + +P +HP + +L+ L + S SPQ P++ S
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 368 SHPSLPASSLARHVLPTTSLGHPSLSAPALSS------SSSSSSTSSPVLGAPSYPASTP 421
PSLP + + H S AP SS S +S ++ G +Y A +P
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 422 -----GASPHHRR-----------VPLSPLSLLAGPADA---------------RRSQQQ 450
SP +R P+ LS P +A +
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 451 LPKQFSPTMSPTLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLV-LP---TQPHTPKSLQ 506
P SP +PT S++T PL ++ LPP +PS+V LP P TP Q
Sbjct: 855 SPTPPSPKGAPTPSAVT---PLSPKGVT----LPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 507 QPGLPSQSCSVQSSGGQP-----PGRQSHYGTPYPPG---PSGHGQQSYHRPMSDFNLGN 558
P L S S + + P P S G P PP PS G + P
Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP-------- 959
Query: 559 LEQFSMESPSASLVLDPPGFSEGPGFLGGEG-----------PMGGPQDP 597
+++ P+A+ PP GP +G P GGP P
Sbjct: 960 --KWAPTPPAAT----PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003
Score = 50.4 bits (119), Expect = 5e-06
Identities = 95/441 (21%), Positives = 135/441 (30%), Gaps = 78/441 (17%)
Query: 170 SSDSALHTSVMNPSPQDTYPGPTPPSILPSRRGGILDGEMDPKVPAIEENLLDDKH---L 226
S DS T +P+P PTP ++ P G+ + P++ NL K
Sbjct: 846 SKDSPATTH--SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV-NLPFPKEGPAT 902
Query: 227 LKPWDAKKLSSSSSRPRSCEVP----GINIFPSPDQPANVPVLPPAMNTGGSLPDLTNLH 282
P A LS +SS P+ GI PSP P P GG
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 283 FPPPLPTPLDPEETAYPSLSGGNSTSNLTHTMTHLGISRGMGLGPGYDAPGLHSPLSHPS 342
PP TP PS GG P SP P+
Sbjct: 963 PTPPAATP--------PSPKGG---------------------------PATPSPKGAPT 987
Query: 343 LQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLSAPALSSSSS 402
++ + P+ + ++P P+ P+ PA V P + G P+ ++
Sbjct: 988 PPAA-TPPSPKGGPATPSPK-----GAPTPPA------VTPPSPKGSPA-------ATPF 1028
Query: 403 SSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPKQFSPTMSPT 462
S+P P P +P A+P + P +P + L P + P +P
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 463 LSSITQGVPLDTSKLSTDQRLPPYP----YSSPSLVLPTQPHTPKSLQQPGL--PSQSCS 516
P PP P + P PT P + GL P +
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 517 VQSSGGQPPGRQSHYGTPYPPGPSGHGQQSYHRPMSDFNLGNLEQFSMESPSASLVLDPP 576
+ PP + TP P G + P G L S + + PP
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK-----GGLATPSPKGAPTTPAATPP 1203
Query: 577 GFSEGPGFLGGEGPMGGPQDP 597
G L P G P P
Sbjct: 1204 ---SPKGGLATPSPKGAPTTP 1221
Score = 33.5 bits (75), Expect = 0.68
Identities = 51/186 (27%), Positives = 75/186 (40%), Gaps = 30/186 (16%)
Query: 334 LHSPLSHPSLQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHVLPTTSLGHPSLS 393
L P+S P+ S LS +L SS + G ++ P P S L H+ P L S
Sbjct: 266 LKGPVSPPAALS-LSTQSLPVVTSSQKTA--GPNTPPDFPIS-LGSHLAP---LHQSSFG 318
Query: 394 APALSSSSSSSSTSSPVLGAPSYPASTPGASPHHRRVPLSPLSLLAGPADARRSQQQLPK 453
+ L + S+ S P + S S+ GAS +R + PL +R
Sbjct: 319 SVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL-------PSRNEVVPATV 371
Query: 454 QFSPTMSP-------TLSSITQGVPLDTSKLSTDQRLPPYPYSSPSLVLPTQP----HTP 502
P ++P T+SSIT P + ++T L P + SL+L + P H P
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCS-PSGSLNVATSFSLSP----TTSLILKSSPNATYHYP 426
Query: 503 KSLQQP 508
Q P
Sbjct: 427 LVAQMP 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.385
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,270,776
Number of Sequences: 37866
Number of extensions: 2327672
Number of successful extensions: 16842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 1252
Number of HSP's that attempted gapping in prelim test: 10334
Number of HSP's gapped (non-prelim): 5457
length of query: 693
length of database: 18,247,518
effective HSP length: 109
effective length of query: 584
effective length of database: 14,120,124
effective search space: 8246152416
effective search space used: 8246152416
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.