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Search of human proteins with 32171201
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32171201 ankyrin repeat domain 37 [Homo sapiens]
(158 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32171201 ankyrin repeat domain 37 [Homo sapiens] 328 2e-90
gi|70995241 ankyrin repeat domain 10 [Homo sapiens] 100 4e-22
gi|110431370 espin [Homo sapiens] 62 2e-10
gi|116875852 HECT domain and ankyrin repeat containing, E3 ubiqu... 57 5e-09
gi|68131557 ankyrin repeat domain 28 [Homo sapiens] 56 1e-08
gi|22208957 ankyrin repeat and SOCS box-containing protein 13 [H... 54 6e-08
gi|22208951 ankyrin repeat and SOCS box-containing protein 3 iso... 54 6e-08
gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isof... 54 6e-08
gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3 ... 53 9e-08
gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2 ... 53 9e-08
gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1 ... 53 9e-08
gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens] 53 9e-08
gi|34304383 Usher syndrome 1G protein [Homo sapiens] 53 9e-08
gi|14195601 protein phosphatase 1, regulatory (inhibitor) subuni... 51 4e-07
gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit... 51 4e-07
gi|157743284 ankyrin repeat domain 52 [Homo sapiens] 51 4e-07
gi|219842214 protein phosphatase 1, regulatory (inhibitor) subun... 50 6e-07
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 50 6e-07
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 50 6e-07
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 50 6e-07
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 50 6e-07
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 50 6e-07
gi|55742857 ankyrin repeat domain 6 [Homo sapiens] 50 8e-07
gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens] 50 8e-07
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 50 8e-07
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 50 1e-06
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 50 1e-06
gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens] 50 1e-06
gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens] 50 1e-06
gi|116325987 ankyrin repeat domain 42 [Homo sapiens] 50 1e-06
>gi|32171201 ankyrin repeat domain 37 [Homo sapiens]
Length = 158
Score = 328 bits (840), Expect = 2e-90
Identities = 158/158 (100%), Positives = 158/158 (100%)
Query: 1 MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQ 60
MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQ
Sbjct: 1 MLLLDCNPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQ 60
Query: 61 DVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIK 120
DVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIK
Sbjct: 61 DVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIK 120
Query: 121 CMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC 158
CMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC
Sbjct: 121 CMQTIKASEHPDRNDCVAVLRQKRSLGSVENTSGKRKC 158
>gi|70995241 ankyrin repeat domain 10 [Homo sapiens]
Length = 420
Score = 100 bits (250), Expect = 4e-22
Identities = 49/112 (43%), Positives = 74/112 (66%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+++ L L+ GA++N Q+P H+AA G L+W +Q GA++N+ D GE P+
Sbjct: 70 KLECLVQLVRAGATLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPI 129
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIK 120
HKAA+ GSLEC+S LVA+ A +DL N +G TA D+A + GF +CA+FL ++
Sbjct: 130 HKAARSGSLECISALVANGAHVDLRNASGLTAADIAQTQGFQECAQFLLNLQ 181
Score = 40.0 bits (92), Expect = 8e-04
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 12/107 (11%)
Query: 34 PVHLAAGSG---LACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
P+H A G C LL Q ++ G P+H AA G LECL LV + A +
Sbjct: 25 PLHRACRDGDLATLCSLLQQTPHAHLASEDSFYGWTPVHWAAHFGKLECLVQLVRAGATL 84
Query: 91 DL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDC 136
++ + QT +A G P C +L I+A + ++ DC
Sbjct: 85 NVSTTRYAQTPAHIAAFGGHPQCLVWL--------IQAGANINKPDC 123
>gi|110431370 espin [Homo sapiens]
Length = 854
Score = 62.4 bits (150), Expect = 2e-10
Identities = 32/86 (37%), Positives = 51/86 (59%), Gaps = 1/86 (1%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H AA G L W L G +++ D+ G PLH AA+ G LEC +LV + A++D+ +
Sbjct: 244 MHFAASRGHTKVLSWLLLHGGEISA-DLWGGTPLHDAAENGELECCQILVVNGAELDVRD 302
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIK 120
++G TA DL+ G C ++L T++
Sbjct: 303 RDGYTAADLSDFNGHSHCTRYLRTVE 328
Score = 37.4 bits (85), Expect = 0.005
Identities = 35/112 (31%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSG-LAC--FLLWQLQTGADLNQQDVLGE 65
E+D L+ L G + DP PVH AA +G L C FL+ + A ++ G
Sbjct: 14 ELDVLRSLHAAGLLGPSLRDPLDALPVHHAARAGKLHCLRFLVEEAALPAAARARN--GA 71
Query: 66 APLHKAAKVGSLECLS-LLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
P H A+ G L CL LL ++ + +G T LA G P+ +L
Sbjct: 72 TPAHDASATGHLACLQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWL 123
Score = 35.4 bits (80), Expect = 0.020
Identities = 38/137 (27%), Positives = 54/137 (39%), Gaps = 7/137 (5%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGA-DLNQQDVLGEAPLHKA 71
L+ LL G D + +HLAA G + W L G D +G P+H A
Sbjct: 86 LQWLLSQGGCRVQDKDNSGATVLHLAARFGHPEVVNWLLHHGGGDPTAATDMGALPIHYA 145
Query: 72 AKVGSLECLSLLVASDAQ-IDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEH 130
A G L LLV + ++ KNG T LA G + ++L +Q A H
Sbjct: 146 AAKGDFPSLRLLVEHYPEGVNAQTKNGATPLYLACQEGHLEVTQYL-----VQECGADPH 200
Query: 131 PDRNDCVAVLRQKRSLG 147
+D + L +G
Sbjct: 201 ARAHDGMTPLHAAAQMG 217
Score = 30.0 bits (66), Expect = 0.86
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 33 SPVHLAAGSGLACFLLWQLQT-GADLNQQDVLGEAPLHKAAKVGSLECLSLLVA-SDAQI 90
+P++LA G + +Q GAD + + G PLH AA++G + LV+ +D +
Sbjct: 174 TPLYLACQEGHLEVTQYLVQECGADPHARAHDGMTPLHAAAQMGHSPVIVWLVSCTDVSL 233
Query: 91 DLCNKNGQTAEDLAWSCG 108
+K+G TA A S G
Sbjct: 234 SEQDKDGATAMHFAASRG 251
>gi|116875852 HECT domain and ankyrin repeat containing, E3
ubiquitin protein ligase 1 [Homo sapiens]
Length = 909
Score = 57.4 bits (137), Expect = 5e-09
Identities = 29/70 (41%), Positives = 43/70 (61%)
Query: 31 KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
K+S +H+AA G L+ L+ GA+ N QD+ G PLH AA+ G +C+S L+ A +
Sbjct: 65 KRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADV 124
Query: 91 DLCNKNGQTA 100
++CN G TA
Sbjct: 125 NICNNEGLTA 134
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D Q+ +H+A +G + L +GAD+N+ +V G PL+ A G + +L+
Sbjct: 161 DAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRG 220
Query: 88 AQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
A+ L +KNG T DL G+ + + L
Sbjct: 221 AKY-LPDKNGVTPLDLCVQGGYGETCEVL 248
Score = 38.5 bits (88), Expect = 0.002
Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 7/113 (6%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ L LL+ GA+ N D +P+HLAA +G + L+ AD+N + G +H
Sbjct: 78 VECLVLLLKKGANPNYQ-DISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIH 136
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCM 122
A G E L LV + +D+ + GQTA +A G TT++C+
Sbjct: 137 WLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHK------TTVQCL 183
Score = 28.1 bits (61), Expect = 3.3
Identities = 18/45 (40%), Positives = 23/45 (51%)
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDC 112
LH AA GS+ECL LL+ A + + +G T LA G C
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKC 113
>gi|68131557 ankyrin repeat domain 28 [Homo sapiens]
Length = 1053
Score = 55.8 bits (133), Expect = 1e-08
Identities = 48/150 (32%), Positives = 69/150 (46%), Gaps = 17/150 (11%)
Query: 11 DGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHK 70
D + LL +G ++ P D + AAG L C L L TGAD N++D G +PLH
Sbjct: 386 DCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL-LNTGADFNKKDKFGRSPLHY 444
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEH 130
AA + +CL LV S A ++ ++ G T A A T KC+ E+
Sbjct: 445 AAANCNYQCLFALVGSGASVNDLDERGCTPLHYA--------ATSDTDGKCL------EY 490
Query: 131 PDRNDCVAVLRQKRSLGSVENTS--GKRKC 158
RND +R K+ +V ++ G R C
Sbjct: 491 LLRNDANPGIRDKQGYNAVHYSAAYGHRLC 520
Score = 48.1 bits (113), Expect = 3e-06
Identities = 29/88 (32%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH-KA 71
+K+LL+ G +N P + +P+H+A +G + + GA +NQ++ G PLH A
Sbjct: 222 VKYLLDLGVDMNEP-NAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFAA 280
Query: 72 AKVGSLECLSLLVASDAQIDLCNKNGQT 99
A CL LLV + A +++ +K+G+T
Sbjct: 281 ASTHGALCLELLVGNGADVNMKSKDGKT 308
Score = 45.8 bits (107), Expect = 2e-05
Identities = 26/66 (39%), Positives = 39/66 (59%)
Query: 34 PVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLC 93
P+HLAA SG + L +G D++ D G LH AA G+LECL+LL+ + A +
Sbjct: 375 PLHLAALSGFSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKK 434
Query: 94 NKNGQT 99
+K G++
Sbjct: 435 DKFGRS 440
Score = 44.7 bits (104), Expect = 3e-05
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 1/90 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
++ +K L+ GA V D +P+H AA SG+ + + L G D+N+ + G PLH
Sbjct: 186 IEVVKLLVSHGAEVTCK-DKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLH 244
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQT 99
A G ++ L+ A ++ N+ G T
Sbjct: 245 VACYNGQDVVVNELIDCGAIVNQKNEKGFT 274
Score = 44.3 bits (103), Expect = 4e-05
Identities = 29/101 (28%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
++++GA ++ D +P+H+AA G + + +GAD ++ + G PLH AA G
Sbjct: 325 IIQSGAVIDCE-DKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSG 383
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+C L++S ID + G+T A + G +C L
Sbjct: 384 FSDCCRKLLSSGFDIDTPDDFGRTCLHAAAAGGNLECLNLL 424
Score = 43.1 bits (100), Expect = 1e-04
Identities = 32/94 (34%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGS--GLACFLLWQLQTGADLNQQDVLGEAPLHK 70
+ L++ GA VN + +P+H AA S G C L + GAD+N + G+ PLH
Sbjct: 255 VNELIDCGAIVNQKNEK-GFTPLHFAAASTHGALCLELL-VGNGADVNMKSKDGKTPLHM 312
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
A G ++ S A ID +KNG T +A
Sbjct: 313 TALHGRFSRSQTIIQSGAVIDCEDKNGNTPLHIA 346
Score = 42.7 bits (99), Expect = 1e-04
Identities = 35/127 (27%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEA 66
N + D ++ L+ VN D K++P+H AA G A + + +GA +N +D
Sbjct: 18 NGDPDEVRALIFKKEDVNFQ-DNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLT 76
Query: 67 PLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIK 126
PLH+A S E + +L+ A ++ +KN QT +A + CA+ L + + +
Sbjct: 77 PLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKAVKCAEAL--VPLLSNVN 134
Query: 127 ASEHPDR 133
S+ R
Sbjct: 135 VSDRAGR 141
Score = 42.4 bits (98), Expect = 2e-04
Identities = 34/107 (31%), Positives = 51/107 (47%), Gaps = 2/107 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
L LL TGA N D +SP+H AA + L + +GA +N D G PLH AA
Sbjct: 421 LNLLLNTGADFNKK-DKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDERGCTPLHYAA 479
Query: 73 KVGSL-ECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTT 118
+ +CL L+ +DA + +K G A + + G C + + +
Sbjct: 480 TSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIAS 526
Score = 40.0 bits (92), Expect = 8e-04
Identities = 31/101 (30%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
L+ +GA VNA D +P+H A S + L+ AD+N +D + PLH AA
Sbjct: 60 LILSGARVNAK-DSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANK 118
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+++C LV + +++ ++ G+TA A G + K L
Sbjct: 119 AVKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLL 159
Score = 40.0 bits (92), Expect = 8e-04
Identities = 27/89 (30%), Positives = 42/89 (47%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D ++ +H AA SG + L GA++N D +H AA +G +E + LLV+
Sbjct: 137 DRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHG 196
Query: 88 AQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
A++ +K T A S G K+L
Sbjct: 197 AEVTCKDKKSYTPLHAAASSGMISVVKYL 225
Score = 40.0 bits (92), Expect = 8e-04
Identities = 30/90 (33%), Positives = 45/90 (50%), Gaps = 6/90 (6%)
Query: 33 SPVHLAA---GSGLACFLLWQLQTGADL-NQQDVLGEAPLHKAAKVGSLECLSLLVASDA 88
SP+H A G A L+ L GA + N D G PLH AA +ECL LL++ +A
Sbjct: 790 SPLHCAVINDNEGAAEMLIDTL--GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNA 847
Query: 89 QIDLCNKNGQTAEDLAWSCGFPDCAKFLTT 118
Q++ + G+T +A G + + L +
Sbjct: 848 QVNSVDSTGKTPLMMAAENGQTNTVEMLVS 877
Score = 39.7 bits (91), Expect = 0.001
Identities = 23/77 (29%), Positives = 40/77 (51%)
Query: 32 QSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQID 91
Q+P+ L+ +G + L GA+++ +D G LH+ A G EC+ L+ A+
Sbjct: 654 QTPLMLSVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCL 713
Query: 92 LCNKNGQTAEDLAWSCG 108
L + G+T L+ +CG
Sbjct: 714 LRDSRGRTPIHLSAACG 730
Score = 39.7 bits (91), Expect = 0.001
Identities = 32/95 (33%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 16 LLET-GASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
L++T GAS+ D ++P+H AA + L L A +N D G+ PL AA+
Sbjct: 807 LIDTLGASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAEN 866
Query: 75 GSLECLSLLVAS-DAQIDLCNKNGQTAEDLAWSCG 108
G + +LV+S A++ L + + TA LA S G
Sbjct: 867 GQTNTVEMLVSSASAELTLQDNSKNTALHLACSKG 901
Score = 38.1 bits (87), Expect = 0.003
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLA-CFLLW----QLQTGADLNQQDVLGEAPLHK 70
L+ GAS+ K++P+H AA +G + C L + Q D+ QD G+ PL
Sbjct: 602 LINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVDI--QDGNGQTPLML 659
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+ G +C+ L+ A +D +K G+TA G +C L
Sbjct: 660 SVLNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDAL 705
Score = 35.8 bits (81), Expect = 0.016
Identities = 37/122 (30%), Positives = 56/122 (45%), Gaps = 15/122 (12%)
Query: 9 EVDG--LKHLLETGASVNAPPDPCKQSPVHLAAGSG-LACFLLWQLQTGADLNQQ----D 61
+ DG L++LL A+ D + VH +A G C L +T D+ + D
Sbjct: 482 DTDGKCLEYLLRNDANPGIR-DKQGYNAVHYSAAYGHRLCLQLIASETPLDVLMETSGTD 540
Query: 62 VLGEA-------PLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAK 114
+L ++ PLH AA G + L +LV S +D+ N +G+T DLA G +C
Sbjct: 541 MLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVD 600
Query: 115 FL 116
L
Sbjct: 601 VL 602
Score = 35.4 bits (80), Expect = 0.020
Identities = 22/58 (37%), Positives = 32/58 (55%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
SP+HLAA G L +Q+ DL+ ++ G PL AA G +EC+ +L+ A I
Sbjct: 552 SPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASI 609
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K LL GA++NA D + +H AA G + + GA++ +D PLH AA
Sbjct: 156 VKLLLSRGANINAF-DKKDRRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAA 214
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQT 99
G + + L+ ++ N G T
Sbjct: 215 SSGMISVVKYLLDLGVDMNEPNAYGNT 241
Score = 30.8 bits (68), Expect = 0.50
Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGAD---LNQQDVL 63
N + + ++ L+ + ++ D K + +HLA G L L+ D +N +
Sbjct: 866 NGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAA 925
Query: 64 GEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQT 99
+ PLH AA+ G + L+ A + ++NG T
Sbjct: 926 LQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYT 961
Score = 28.5 bits (62), Expect = 2.5
Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 32 QSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAP-LHKAAKVGSLECLSLLVAS 86
Q+P+H+AA +GL + L GA + D G P L A +CL+L++A+
Sbjct: 927 QTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTPALACAPNKDVADCLALILAT 982
>gi|22208957 ankyrin repeat and SOCS box-containing protein 13 [Homo
sapiens]
Length = 278
Score = 53.9 bits (128), Expect = 6e-08
Identities = 32/86 (37%), Positives = 48/86 (55%)
Query: 31 KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
+++PVH AA G + L +++GA +NQ V PLH A+ G C+ LL+A+ AQ+
Sbjct: 19 ERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQV 78
Query: 91 DLCNKNGQTAEDLAWSCGFPDCAKFL 116
D N +G T A + G +C K L
Sbjct: 79 DARNIDGSTPLCDACASGSIECVKLL 104
Score = 46.2 bits (108), Expect = 1e-05
Identities = 34/109 (31%), Positives = 56/109 (51%), Gaps = 6/109 (5%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
L+ L+E+GA VN +P+H A+ G A + L GA ++ +++ G PL A
Sbjct: 35 LQQLIESGACVNQVTVD-SITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDAC 93
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSC--GFPDCAKFLTTI 119
GS+EC+ LL++ A++ N TA L +C G +C + L +
Sbjct: 94 ASGSIECVKLLLSYGAKV---NPPLYTASPLHEACMSGSSECVRLLIDV 139
Score = 38.5 bits (88), Expect = 0.002
Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 2/82 (2%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
++ +K LL GA VN P SP+H A SG + + + GA+L D PLH
Sbjct: 98 IECVKLLLSYGAKVNPPLYTA--SPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLH 155
Query: 70 KAAKVGSLECLSLLVASDAQID 91
A L+C+ +L+ + A ++
Sbjct: 156 VACAREHLDCVKVLLNAGANVN 177
Score = 37.7 bits (86), Expect = 0.004
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLA-AGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
L++ GA++ A D +P+H+A A L C + L GA++N L E LH AAKV
Sbjct: 136 LIDVGANLEAH-DCHFGTPLHVACAREHLDCVKVL-LNAGANVNAAK-LHETALHHAAKV 192
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFP 110
+++ + +L+ I + G+ D WS P
Sbjct: 193 KNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAP 228
Score = 33.5 bits (75), Expect = 0.077
Identities = 30/101 (29%), Positives = 44/101 (43%), Gaps = 2/101 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL GA V+A A + C L L GA +N + +PLH+A G
Sbjct: 71 LLAAGAQVDARNIDGSTPLCDACASGSIECVKLL-LSYGAKVNPP-LYTASPLHEACMSG 128
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
S EC+ LL+ A ++ + + T +A + DC K L
Sbjct: 129 SSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVL 169
>gi|22208951 ankyrin repeat and SOCS box-containing protein 3
isoform b [Homo sapiens]
Length = 445
Score = 53.9 bits (128), Expect = 6e-08
Identities = 36/110 (32%), Positives = 56/110 (50%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEA 66
N ++D L+ LL+ GA+VN C + +H A+ A + L+ GA+ QD G
Sbjct: 49 NGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGIT 108
Query: 67 PLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
PL AA+ G LE LS+L++S A ++ + T +A G C + L
Sbjct: 109 PLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 158
Score = 33.1 bits (74), Expect = 0.10
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGAD--LNQQDVLGEA 66
+++ L L+ +GA+VN K +P+ +AA G + L +GAD L + +
Sbjct: 118 KLESLSILISSGANVNCQALD-KATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQL 176
Query: 67 PLHKAAKVGSLECLSLLV 84
P+H AA++G + L LL+
Sbjct: 177 PIHAAAQMGHTKILDLLI 194
Score = 29.6 bits (65), Expect = 1.1
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQID 91
+HLAA G + L+ GAD N + PL A + G ++ L LL+ A ++
Sbjct: 10 LHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVN 66
>gi|7705831 ankyrin repeat and SOCS box-containing protein 3 isoform
a [Homo sapiens]
Length = 518
Score = 53.9 bits (128), Expect = 6e-08
Identities = 36/110 (32%), Positives = 56/110 (50%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEA 66
N ++D L+ LL+ GA+VN C + +H A+ A + L+ GA+ QD G
Sbjct: 122 NGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGIT 181
Query: 67 PLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
PL AA+ G LE LS+L++S A ++ + T +A G C + L
Sbjct: 182 PLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELL 231
Score = 36.2 bits (82), Expect = 0.012
Identities = 23/61 (37%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D C S V LAA G L L+ G ++ D G P+H+AA S+ECL +L+ +D
Sbjct: 9 DTC--STVGLAAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINAD 66
Query: 88 A 88
+
Sbjct: 67 S 67
Score = 33.1 bits (74), Expect = 0.10
Identities = 24/78 (30%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGAD--LNQQDVLGEA 66
+++ L L+ +GA+VN K +P+ +AA G + L +GAD L + +
Sbjct: 191 KLESLSILISSGANVNCQALD-KATPLFIAAQEGHTKCVELLLSSGADPDLYCNEDSWQL 249
Query: 67 PLHKAAKVGSLECLSLLV 84
P+H AA++G + L LL+
Sbjct: 250 PIHAAAQMGHTKILDLLI 267
Score = 29.6 bits (65), Expect = 1.1
Identities = 18/57 (31%), Positives = 28/57 (49%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQID 91
+HLAA G + L+ GAD N + PL A + G ++ L LL+ A ++
Sbjct: 83 LHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVN 139
>gi|46519154 ankyrin repeat and KH domain containing 1 isoform 3
[Homo sapiens]
Length = 627
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA+L + + G PL
Sbjct: 418 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLM 476
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+A A I+ + Q TA LA GF + A FL
Sbjct: 477 EAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL 524
Score = 43.5 bits (101), Expect = 7e-05
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + + ++ GAD+ LG PL +A++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIE----LGCSTPLMEASQE 545
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+AS A + G TA A G D A L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 36.2 bits (82), Expect = 0.012
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL+ GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 351 VEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALM 410
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 411 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 448
Score = 34.3 bits (77), Expect = 0.045
Identities = 24/84 (28%), Positives = 38/84 (45%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ A+ G + L AD+N Q G L A G ++ + +L+ A I+
Sbjct: 274 TPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIED 333
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 334 HNENGHTPLMEAASAGHVEVARVL 357
Score = 33.5 bits (75), Expect = 0.077
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 2/121 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
+D +K LL A VN+ + + AG G + L GA++ + G PL
Sbjct: 285 LDIVKLLLLHDADVNSQSATGNTALTYACAG-GFVDIVKVLLNEGANIEDHNENGHTPLM 343
Query: 70 KAAKVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKAS 128
+AA G +E +L+ A I+ N+ ++A LA G D +FL Q K
Sbjct: 344 EAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTD 403
Query: 129 E 129
E
Sbjct: 404 E 404
>gi|46519151 ankyrin repeat and KH domain containing 1 isoform 2
[Homo sapiens]
Length = 616
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA+L + + G PL
Sbjct: 407 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLM 465
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+A A I+ + Q TA LA GF + A FL
Sbjct: 466 EAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL 513
Score = 43.5 bits (101), Expect = 7e-05
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + + ++ GAD+ LG PL +A++
Sbjct: 479 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIE----LGCSTPLMEASQE 534
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+AS A + G TA A G D A L
Sbjct: 535 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 576
Score = 36.2 bits (82), Expect = 0.012
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL+ GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 340 VEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALM 399
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 400 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 437
Score = 34.3 bits (77), Expect = 0.045
Identities = 24/84 (28%), Positives = 38/84 (45%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ A+ G + L AD+N Q G L A G ++ + +L+ A I+
Sbjct: 263 TPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIED 322
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 323 HNENGHTPLMEAASAGHVEVARVL 346
Score = 33.5 bits (75), Expect = 0.077
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 2/121 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
+D +K LL A VN+ + + AG G + L GA++ + G PL
Sbjct: 274 LDIVKLLLLHDADVNSQSATGNTALTYACAG-GFVDIVKVLLNEGANIEDHNENGHTPLM 332
Query: 70 KAAKVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKAS 128
+AA G +E +L+ A I+ N+ ++A LA G D +FL Q K
Sbjct: 333 EAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTD 392
Query: 129 E 129
E
Sbjct: 393 E 393
>gi|46519147 ankyrin repeat and KH domain containing 1 isoform 1
[Homo sapiens]
Length = 2542
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA+L + + G PL
Sbjct: 418 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLM 476
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+A A I+ + Q TA LA GF + A FL
Sbjct: 477 EAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL 524
Score = 44.3 bits (103), Expect = 4e-05
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 9/119 (7%)
Query: 16 LLETGASVNAPPDPC-KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
LL+ GA VNAPP P + + + +AA G F + GA ++ ++ G PL A+
Sbjct: 1276 LLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 1335
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL--------TTIKCMQTI 125
G + + LLV + A +D + T A+ G ++L + I+CM+ I
Sbjct: 1336 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPSDIECMRYI 1394
Score = 43.5 bits (101), Expect = 7e-05
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + + ++ GAD+ LG PL +A++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIE----LGCSTPLMEASQE 545
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+AS A + G TA A G D A L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 38.1 bits (87), Expect = 0.003
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K+LL +GA+V+A + + A +G LQ GADL + G PL KAA
Sbjct: 551 VKYLLASGANVHATT-ATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAA 609
Query: 73 KVGSLECLSLLVASDAQIDLCN-KNGQTAEDLAWSCG 108
+ G L + L++ A ++ N T LA + G
Sbjct: 610 RAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGG 646
Score = 36.2 bits (82), Expect = 0.012
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL+ GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 351 VEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALM 410
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 411 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 448
Score = 34.7 bits (78), Expect = 0.035
Identities = 21/76 (27%), Positives = 37/76 (48%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ G + A + K +P+ LA G + L GA+ ++V PL AA G
Sbjct: 1107 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGG 1166
Query: 76 SLECLSLLVASDAQID 91
+ + +L+ + A+I+
Sbjct: 1167 YVNIIKILLNAGAEIN 1182
Score = 34.3 bits (77), Expect = 0.045
Identities = 24/84 (28%), Positives = 38/84 (45%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ A+ G + L AD+N Q G L A G ++ + +L+ A I+
Sbjct: 274 TPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIED 333
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 334 HNENGHTPLMEAASAGHVEVARVL 357
Score = 33.5 bits (75), Expect = 0.077
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 2/121 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
+D +K LL A VN+ + + AG G + L GA++ + G PL
Sbjct: 285 LDIVKLLLLHDADVNSQSATGNTALTYACAG-GFVDIVKVLLNEGANIEDHNENGHTPLM 343
Query: 70 KAAKVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKAS 128
+AA G +E +L+ A I+ N+ ++A LA G D +FL Q K
Sbjct: 344 EAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTD 403
Query: 129 E 129
E
Sbjct: 404 E 404
Score = 29.6 bits (65), Expect = 1.1
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQ--DVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
+P+ LAA G + L GA++N + LG +PL AA G + + LL+ + I
Sbjct: 1157 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216
Query: 91 DL-CNKNGQTAEDLA 104
+ N TA LA
Sbjct: 1217 NAQIETNRNTALTLA 1231
Score = 27.3 bits (59), Expect = 5.6
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 27 PDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVAS 86
P+ C Q+ ++A+ S + + + N + L A G E +S+L+A
Sbjct: 1023 PESCSQTTSNVASQSMPPVYPSVDIDAHTESNH-----DTALTLACAGGHEELVSVLIAR 1077
Query: 87 DAQIDLCNKNGQTAEDLAWSCG 108
DA+I+ +K G T LA + G
Sbjct: 1078 DAKIEHRDKKGFTPLILAATAG 1099
>gi|37620163 ANKHD1-EIF4EBP3 protein [Homo sapiens]
Length = 2617
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/108 (37%), Positives = 59/108 (54%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA+L + + G PL
Sbjct: 418 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGANLEEVNDEGYTPLM 476
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+A A I+ + Q TA LA GF + A FL
Sbjct: 477 EAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL 524
Score = 44.3 bits (103), Expect = 4e-05
Identities = 34/119 (28%), Positives = 56/119 (47%), Gaps = 9/119 (7%)
Query: 16 LLETGASVNAPPDPC-KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
LL+ GA VNAPP P + + + +AA G F + GA ++ ++ G PL A+
Sbjct: 1276 LLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIHRGAHIDVRNKKGNTPLWLASNG 1335
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL--------TTIKCMQTI 125
G + + LLV + A +D + T A+ G ++L + I+CM+ I
Sbjct: 1336 GHFDVVQLLVQAGADVDAADNRKITPLMSAFRKGHVKVVQYLVKEVNQFPSDIECMRYI 1394
Score = 43.5 bits (101), Expect = 7e-05
Identities = 32/102 (31%), Positives = 50/102 (49%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + + ++ GAD+ LG PL +A++
Sbjct: 490 LLAQGANINAQTEETQETALTLACCGGFSEVADFLIKAGADIE----LGCSTPLMEASQE 545
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+AS A + G TA A G D A L
Sbjct: 546 GHLELVKYLLASGANVHATTATGDTALTYACENGHTDVADVL 587
Score = 38.1 bits (87), Expect = 0.003
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 2/97 (2%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K+LL +GA+V+A + + A +G LQ GADL + G PL KAA
Sbjct: 551 VKYLLASGANVHATT-ATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAA 609
Query: 73 KVGSLECLSLLVASDAQIDLCN-KNGQTAEDLAWSCG 108
+ G L + L++ A ++ N T LA + G
Sbjct: 610 RAGHLCTVQFLISKGANVNRATANNDHTVVSLACAGG 646
Score = 36.2 bits (82), Expect = 0.012
Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL+ GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 351 VEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTDEMHTALM 410
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 411 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 448
Score = 34.7 bits (78), Expect = 0.035
Identities = 21/76 (27%), Positives = 37/76 (48%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ G + A + K +P+ LA G + L GA+ ++V PL AA G
Sbjct: 1107 LLDKGGDIEAQSERTKDTPLSLACSGGRQEVVDLLLARGANKEHRNVSDYTPLSLAASGG 1166
Query: 76 SLECLSLLVASDAQID 91
+ + +L+ + A+I+
Sbjct: 1167 YVNIIKILLNAGAEIN 1182
Score = 34.3 bits (77), Expect = 0.045
Identities = 24/84 (28%), Positives = 38/84 (45%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ A+ G + L AD+N Q G L A G ++ + +L+ A I+
Sbjct: 274 TPLMAASSGGYLDIVKLLLLHDADVNSQSATGNTALTYACAGGFVDIVKVLLNEGANIED 333
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 334 HNENGHTPLMEAASAGHVEVARVL 357
Score = 33.5 bits (75), Expect = 0.077
Identities = 34/121 (28%), Positives = 52/121 (42%), Gaps = 2/121 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
+D +K LL A VN+ + + AG G + L GA++ + G PL
Sbjct: 285 LDIVKLLLLHDADVNSQSATGNTALTYACAG-GFVDIVKVLLNEGANIEDHNENGHTPLM 343
Query: 70 KAAKVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKAS 128
+AA G +E +L+ A I+ N+ ++A LA G D +FL Q K
Sbjct: 344 EAASAGHVEVARVLLDHGAGINTHSNEFKESALTLACYKGHLDMVRFLLEAGADQEHKTD 403
Query: 129 E 129
E
Sbjct: 404 E 404
Score = 29.6 bits (65), Expect = 1.1
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQ--DVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
+P+ LAA G + L GA++N + LG +PL AA G + + LL+ + I
Sbjct: 1157 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHVPAVKLLLDMGSDI 1216
Query: 91 DL-CNKNGQTAEDLA 104
+ N TA LA
Sbjct: 1217 NAQIETNRNTALTLA 1231
Score = 27.3 bits (59), Expect = 5.6
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 27 PDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVAS 86
P+ C Q+ ++A+ S + + + N + L A G E +S+L+A
Sbjct: 1023 PESCSQTTSNVASQSMPPVYPSVDIDAHTESNH-----DTALTLACAGGHEELVSVLIAR 1077
Query: 87 DAQIDLCNKNGQTAEDLAWSCG 108
DA+I+ +K G T LA + G
Sbjct: 1078 DAKIEHRDKKGFTPLILAATAG 1099
>gi|34304383 Usher syndrome 1G protein [Homo sapiens]
Length = 461
Score = 53.1 bits (126), Expect = 9e-08
Identities = 40/116 (34%), Positives = 56/116 (48%), Gaps = 3/116 (2%)
Query: 11 DGLKHLLE--TGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
DG LL+ T +NAP D +P AA G L + G D ++ D+ G PL
Sbjct: 11 DGYLELLKEATRKELNAP-DEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPL 69
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQT 124
H AA G L CLS LV+ A I + + T D+A G +C ++L +I Q+
Sbjct: 70 HLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQS 125
>gi|14195601 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform b [Homo sapiens]
Length = 998
Score = 51.2 bits (121), Expect = 4e-07
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA G + L +Q G +LN QD G PLH AA G E S+L + +D+ N
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRN 280
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCV 137
K GQT D+A + L ++ Q + SE RN +
Sbjct: 281 KLGQTPFDVA----DEGLVEHLELLQKKQNVLRSEKETRNKLI 319
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+ D ++ LL GA +N + + +H A + + ++ A++NQQD G PL
Sbjct: 70 DTDEVRKLLARGADINTV-NVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPL 128
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
H AA G L + A + + N G+ DLA
Sbjct: 129 HAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLA 164
Score = 36.6 bits (83), Expect = 0.009
Identities = 21/65 (32%), Positives = 35/65 (53%)
Query: 51 LQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFP 110
L GAD+N +V G LH+A +L+ + LV + A ++ + G T A SCG+
Sbjct: 78 LARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYL 137
Query: 111 DCAKF 115
+ A++
Sbjct: 138 NIAEY 142
Score = 26.6 bits (57), Expect = 9.5
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 64 GEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQ 123
G LH AA G E L LL+ + ++++ + +G T A G + L C
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 124 TIK 126
I+
Sbjct: 277 DIR 279
>gi|4505319 protein phosphatase 1, regulatory (inhibitor) subunit
12B isoform a [Homo sapiens]
Length = 982
Score = 51.2 bits (121), Expect = 4e-07
Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA G + L +Q G +LN QD G PLH AA G E S+L + +D+ N
Sbjct: 221 LHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDMDIRN 280
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCV 137
K GQT D+A + L ++ Q + SE RN +
Sbjct: 281 KLGQTPFDVA----DEGLVEHLELLQKKQNVLRSEKETRNKLI 319
Score = 41.6 bits (96), Expect = 3e-04
Identities = 27/96 (28%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+ D ++ LL GA +N + + +H A + + ++ A++NQQD G PL
Sbjct: 70 DTDEVRKLLARGADINTV-NVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPL 128
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
H AA G L + A + + N G+ DLA
Sbjct: 129 HAAASCGYLNIAEYFINHGASVGIVNSEGEVPSDLA 164
Score = 36.6 bits (83), Expect = 0.009
Identities = 21/65 (32%), Positives = 35/65 (53%)
Query: 51 LQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFP 110
L GAD+N +V G LH+A +L+ + LV + A ++ + G T A SCG+
Sbjct: 78 LARGADINTVNVDGLTALHQACIDENLDMVKFLVENRANVNQQDNEGWTPLHAAASCGYL 137
Query: 111 DCAKF 115
+ A++
Sbjct: 138 NIAEY 142
Score = 26.6 bits (57), Expect = 9.5
Identities = 17/63 (26%), Positives = 27/63 (42%)
Query: 64 GEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQ 123
G LH AA G E L LL+ + ++++ + +G T A G + L C
Sbjct: 217 GATALHVAAAKGYSEVLRLLIQAGYELNVQDYDGWTPLHAAAHWGVKEACSILAEALCDM 276
Query: 124 TIK 126
I+
Sbjct: 277 DIR 279
>gi|157743284 ankyrin repeat domain 52 [Homo sapiens]
Length = 1076
Score = 51.2 bits (121), Expect = 4e-07
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 14 KHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
+H+L G +N P D ++ +H AA G L L +GADL ++D G PLH AA
Sbjct: 407 EHVLSAGFDINTP-DNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAA 465
Query: 74 VGSLECLSLLVASDAQIDLCNKNG 97
GS +C LV + A ++ + G
Sbjct: 466 NGSYQCAVTLVTAGAGVNEADCKG 489
Score = 49.3 bits (116), Expect = 1e-06
Identities = 33/86 (38%), Positives = 48/86 (55%), Gaps = 4/86 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGS--GLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
L+ GA+VN P D +P+H+AA S G C L + GAD+N Q G++PLH AA
Sbjct: 258 LVNAGANVNQPNDK-GFTPLHVAAVSTNGALCLELL-VNNGADVNYQSKEGKSPLHMAAI 315
Query: 74 VGSLECLSLLVASDAQIDLCNKNGQT 99
G +L+ + ++ID +K G T
Sbjct: 316 HGRFTRSQILIQNGSEIDCADKFGNT 341
Score = 48.5 bits (114), Expect = 2e-06
Identities = 34/111 (30%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+V+ ++ LL ++N D +++P+H AA G L L +GA++N +D L PL
Sbjct: 20 DVEEVRSLLSQKENINVL-DQERRTPLHAAAYVGDVPILQLLLMSGANVNAKDTLWLTPL 78
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTI 119
H+AA + + L LL+A A ++ +K QT +A + CA+ L +
Sbjct: 79 HRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAEALAPL 129
Score = 47.8 bits (112), Expect = 4e-06
Identities = 28/68 (41%), Positives = 38/68 (55%)
Query: 51 LQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFP 110
L G D+N D LG LH AA G++ECL+LL++S A + +K G+T A + G
Sbjct: 410 LSAGFDINTPDNLGRTCLHAAASGGNVECLNLLLSSGADLRRRDKFGRTPLHYAAANGSY 469
Query: 111 DCAKFLTT 118
CA L T
Sbjct: 470 QCAVTLVT 477
Score = 46.2 bits (108), Expect = 1e-05
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL GAS+N D ++ P+H AA G L + GADL +D G LH AA G
Sbjct: 159 LLNKGASLNVC-DKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASG 217
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+E + L+ A+ID N G TA +A G
Sbjct: 218 QIEVVKYLLRMGAEIDEPNAFGNTALHIACYLG 250
Score = 45.1 bits (105), Expect = 3e-05
Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 1/92 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+V L+ LL +GA+VNA D +P+H AA S L L AD+N +D L + PL
Sbjct: 53 DVPILQLLLMSGANVNAK-DTLWLTPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPL 111
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTA 100
H AA + +C L + +++ +++G++A
Sbjct: 112 HVAAANRATKCAEALAPLLSSLNVADRSGRSA 143
Score = 44.3 bits (103), Expect = 4e-05
Identities = 28/97 (28%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+++ +K+LL GA ++ P + + +H+A G + + GA++NQ + G PL
Sbjct: 218 QIEVVKYLLRMGAEIDEP-NAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPL 276
Query: 69 HKAA-KVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
H AA CL LLV + A ++ +K G++ +A
Sbjct: 277 HVAAVSTNGALCLELLVNNGADVNYQSKEGKSPLHMA 313
Score = 43.9 bits (102), Expect = 6e-05
Identities = 35/116 (30%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
L+ L+ GA VN K SP+H+AA G +Q G++++ D G PLH AA
Sbjct: 289 LELLVNNGADVNYQSKEGK-SPLHMAAIHGRFTRSQILIQNGSEIDCADKFGNTPLHVAA 347
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKAS 128
+ G +S L+ + A + LA GF DC + L + + +I +S
Sbjct: 348 RYGHELLISTLMTNGADTARRGIHDMFPLHLAVLFGFSDCCRKLLSSGQLYSIVSS 403
Score = 43.5 bits (101), Expect = 7e-05
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
Query: 11 DGLKHLLETG--ASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
D L L+++G A + D Q+P+ LA +G + L+ G+ + D+ G L
Sbjct: 666 DSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGHVDCVHLLLEKGSTADAADLRGRTAL 725
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
H+ A G +CL+ L+ DA + + G+T LA +CG
Sbjct: 726 HRGAVTGCEDCLAALLDHDAFVLCRDFKGRTPIHLASACG 765
Score = 40.4 bits (93), Expect = 6e-04
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 5/100 (5%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEA 66
N +V GL LL A VNA D Q+P+H+AA + + LN D G +
Sbjct: 86 NEKVLGL--LLAHSADVNAR-DKLWQTPLHVAAANRATKCAEALAPLLSSLNVADRSGRS 142
Query: 67 PLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWS 106
LH A G LE ++LL+ A +++C+K + + L W+
Sbjct: 143 ALHHAVHSGHLETVNLLLNKGASLNVCDK--KERQPLHWA 180
Score = 40.0 bits (92), Expect = 8e-04
Identities = 31/89 (34%), Positives = 41/89 (46%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D +S +H A SG + L GA LN D PLH AA +G LE L LLVA
Sbjct: 137 DRSGRSALHHAVHSGHLETVNLLLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARG 196
Query: 88 AQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
A + ++ G A + G + K+L
Sbjct: 197 ADLGCKDRKGYGLLHTAAASGQIEVVKYL 225
Score = 40.0 bits (92), Expect = 8e-04
Identities = 30/96 (31%), Positives = 43/96 (44%), Gaps = 3/96 (3%)
Query: 20 GASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTG--ADLNQ-QDVLGEAPLHKAAKVGS 76
GAS K +P+H AA SG L + +G AD+ D G+ PL A G
Sbjct: 641 GASALIKERKRKWTPLHAAAASGHTDSLHLLIDSGERADITDVMDAYGQTPLMLAIMNGH 700
Query: 77 LECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDC 112
++C+ LL+ + D + G+TA G DC
Sbjct: 701 VDCVHLLLEKGSTADAADLRGRTALHRGAVTGCEDC 736
Score = 37.4 bits (85), Expect = 0.005
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 3/116 (2%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAA--GSGLACFLLWQLQTGADLNQQDVLGEAPLHK 70
L+ LL+ GA + D + VH AA G+ LL ++ + + + +PLH
Sbjct: 533 LEFLLDNGADPSLR-DRQGYTAVHYAAAYGNRQNLELLLEMSFNCLEDVESTIPVSPLHL 591
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIK 126
AA G E L L + +D+ + G+TA LA G +C + LT IK
Sbjct: 592 AAYNGHCEALKTLAETLVNLDVRDHKGRTALFLATERGSTECVEVLTAHGASALIK 647
Score = 34.3 bits (77), Expect = 0.045
Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ L LL +GA + D ++P+H AA +G + + GA +N+ D G +PLH
Sbjct: 436 VECLNLLLSSGADLRRR-DKFGRTPLHYAAANGSYQCAVTLVTAGAGVNEADCKGCSPLH 494
Query: 70 KAA 72
AA
Sbjct: 495 YAA 497
Score = 32.7 bits (73), Expect = 0.13
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
LK L+ GA + D +H AA SG + + L+ GA++++ + G LH A
Sbjct: 189 LKLLVARGADLGCK-DRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNTALHIAC 247
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQT 99
+G LV + A ++ N G T
Sbjct: 248 YLGQDAVAIELVNAGANVNQPNDKGFT 274
Score = 32.7 bits (73), Expect = 0.13
Identities = 18/60 (30%), Positives = 30/60 (50%)
Query: 57 LNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+N +D G PLH AA ++ L +L+ A+++ + G+TA A G +FL
Sbjct: 851 VNSRDAKGRTPLHAAAFADNVSGLRMLLQHQAEVNATDHTGRTALMTAAENGQTAAVEFL 910
Score = 32.7 bits (73), Expect = 0.13
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTG-ADLNQQDVLGEAPL 68
V GL+ LL+ A VNA D ++ + AA +G + + L G ADL D L
Sbjct: 871 VSGLRMLLQHQAEVNAT-DHTGRTALMTAAENGQTAAVEFLLYRGKADLTVLDENKNTAL 929
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCN 94
H A G +C +++A + L N
Sbjct: 930 HLACSKGHEKCALMILAETQDLGLIN 955
Score = 31.6 bits (70), Expect = 0.29
Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)
Query: 32 QSPVHLAAGSGLACFLLWQLQTGADLNQQDV----LGEAPLHKAAKVGSLECLSLLV 84
++P+HLA+ G L LQ + D G +P+H A+ G +CL LL+
Sbjct: 755 RTPIHLASACGHTAVLRTLLQAALSTDPLDAGVDYSGYSPMHWASYTGHEDCLELLL 811
Score = 30.8 bits (68), Expect = 0.50
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 5/119 (4%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSG---LACFLLWQLQTGADLNQQDVL 63
N + ++ LL G + D K + +HLA G A +L + Q +N +
Sbjct: 901 NGQTAAVEFLLYRGKADLTVLDENKNTALHLACSKGHEKCALMILAETQDLGLINATNSA 960
Query: 64 GEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQT-AEDLAWSCGFPDC-AKFLTTIK 120
+ PLH AA+ G + L++ A + ++ G T A A + DC A L+T+K
Sbjct: 961 LQMPLHIAARNGLASVVQALLSHGATVLAVDEEGHTPALACAPNKDVADCLALILSTMK 1019
>gi|219842214 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform b [Homo sapiens]
Length = 943
Score = 50.4 bits (119), Expect = 6e-07
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA G L +Q G D+N +D G PLH AA G E +LV + +++ N
Sbjct: 116 LHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVN 175
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDR 133
K GQTA D+A D +L ++ Q + SE D+
Sbjct: 176 KVGQTAFDVA----DEDILGYLEELQKKQNLLHSEKRDK 210
Score = 41.6 bits (96), Expect = 3e-04
Identities = 20/54 (37%), Positives = 28/54 (51%)
Query: 51 LQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
++ GA++NQ D G PLH AA G L+ L+ A + N G T D+A
Sbjct: 6 VENGANINQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA 59
Score = 29.3 bits (64), Expect = 1.5
Identities = 21/68 (30%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K L+E GA++N P D P+H AA G + + GA + + G+ PL A
Sbjct: 2 VKFLVENGANINQP-DNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAE 60
Query: 73 KVGSLECL 80
+ E L
Sbjct: 61 EEAMEELL 68
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.4 bits (119), Expect = 6e-07
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA G L +Q G D+N +D G PLH AA G E +LV + +++ N
Sbjct: 203 LHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVN 262
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDR 133
K GQTA D+A D +L ++ Q + SE D+
Sbjct: 263 KVGQTAFDVA----DEDILGYLEELQKKQNLLHSEKRDK 297
Score = 43.9 bits (102), Expect = 6e-05
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 9 EVDGLKHLLETGASVN-APPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAP 67
+ D + LL GA +N A D + +H A + + ++ GA++NQ D G P
Sbjct: 52 DTDEVLKLLHRGADINYANVDGL--TALHQACIDDNVDMVKFLVENGANINQPDNEGWIP 109
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
LH AA G L+ L+ A + N G T D+A
Sbjct: 110 LHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA 146
Score = 41.2 bits (95), Expect = 4e-04
Identities = 27/79 (34%), Positives = 40/79 (50%)
Query: 38 AAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNG 97
A SG +L L GAD+N +V G LH+A +++ + LV + A I+ + G
Sbjct: 47 ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
Query: 98 QTAEDLAWSCGFPDCAKFL 116
A SCG+ D A+FL
Sbjct: 107 WIPLHAAASCGYLDIAEFL 125
Score = 32.0 bits (71), Expect = 0.23
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
VD +K L+E GA++N P D P+H AA G + + GA + + G+ PL
Sbjct: 86 VDMVKFLVENGANINQP-DNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLD 144
Query: 70 KAAKVGSLECL 80
A + E L
Sbjct: 145 IAEEEAMEELL 155
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.4 bits (119), Expect = 6e-07
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA G L +Q G D+N +D G PLH AA G E +LV + +++ N
Sbjct: 203 LHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVN 262
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDR 133
K GQTA D+A D +L ++ Q + SE D+
Sbjct: 263 KVGQTAFDVA----DEDILGYLEELQKKQNLLHSEKRDK 297
Score = 43.9 bits (102), Expect = 6e-05
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 9 EVDGLKHLLETGASVN-APPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAP 67
+ D + LL GA +N A D + +H A + + ++ GA++NQ D G P
Sbjct: 52 DTDEVLKLLHRGADINYANVDGL--TALHQACIDDNVDMVKFLVENGANINQPDNEGWIP 109
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
LH AA G L+ L+ A + N G T D+A
Sbjct: 110 LHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIA 146
Score = 41.2 bits (95), Expect = 4e-04
Identities = 27/79 (34%), Positives = 40/79 (50%)
Query: 38 AAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNG 97
A SG +L L GAD+N +V G LH+A +++ + LV + A I+ + G
Sbjct: 47 ACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGANINQPDNEG 106
Query: 98 QTAEDLAWSCGFPDCAKFL 116
A SCG+ D A+FL
Sbjct: 107 WIPLHAAASCGYLDIAEFL 125
Score = 32.0 bits (71), Expect = 0.23
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 1/71 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
VD +K L+E GA++N P D P+H AA G + + GA + + G+ PL
Sbjct: 86 VDMVKFLVENGANINQP-DNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLD 144
Query: 70 KAAKVGSLECL 80
A + E L
Sbjct: 145 IAEEEAMEELL 155
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 50.4 bits (119), Expect = 6e-07
Identities = 34/91 (37%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+ D ++ LL+ GAS NA +P+HL+A G + L GA L+ G PL
Sbjct: 511 KADIVQQLLQQGASPNAATTS-GYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPL 569
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQT 99
H AAK G LE +LL+ A D K+G T
Sbjct: 570 HVAAKYGKLEVANLLLQKSASPDAAGKSGLT 600
Score = 47.4 bits (111), Expect = 5e-06
Identities = 33/101 (32%), Positives = 50/101 (49%), Gaps = 1/101 (0%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GAS+ A + +P+H+AA G + + GA N +V GE LH AA+ G
Sbjct: 419 LLKHGASIQAVTES-GLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSG 477
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
E + LV AQ++ K+ QT ++ G D + L
Sbjct: 478 QAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQL 518
Score = 47.4 bits (111), Expect = 5e-06
Identities = 32/89 (35%), Positives = 48/89 (53%), Gaps = 1/89 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GAS +A +P+H+AA L+ GAD N G A +H AA+ G
Sbjct: 617 LLDQGASPHAAAKN-GYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEG 675
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLA 104
++ +SLL+ +A ++L NK+G T LA
Sbjct: 676 HVDMVSLLLGRNANVNLSNKSGLTPLHLA 704
Score = 46.2 bits (108), Expect = 1e-05
Identities = 31/108 (28%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+ + +++L++ GA V A Q+P+H++A G A + LQ GA N G PL
Sbjct: 478 QAEVVRYLVQDGAQVEAKAKD-DQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPL 536
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
H +A+ G + + L+ A + + K G T +A G + A L
Sbjct: 537 HLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 42.7 bits (99), Expect = 1e-04
Identities = 34/115 (29%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K LL+ GA ++A +P+H A SG + L A + + G +PLH A
Sbjct: 284 VKLLLDRGAKIDAKTRD-GLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMAT 342
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKA 127
+ L C+ LL+ + +D + TA +A CG AK L K KA
Sbjct: 343 QGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKA 397
Score = 41.6 bits (96), Expect = 3e-04
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 1/107 (0%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + L+ GAS N + ++ +H+AA SG A + + +Q GA + + + PLH
Sbjct: 446 VNIVSQLMHHGASPNTT-NVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 504
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+A++G + + L+ A + +G T L+ G D A FL
Sbjct: 505 ISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFL 551
Score = 40.4 bits (93), Expect = 6e-04
Identities = 23/68 (33%), Positives = 35/68 (51%)
Query: 51 LQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFP 110
++ G D+N + G LH A+K G +E +S L+ +A +D K G TA +A G
Sbjct: 61 IKNGVDINICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA 120
Query: 111 DCAKFLTT 118
+ K L T
Sbjct: 121 EVVKVLVT 128
Score = 40.4 bits (93), Expect = 6e-04
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 4/118 (3%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
L+ GA V+A +P+H+ G + + LQ A +N + G PLH+AA+ G
Sbjct: 716 LVNQGAHVDAQTK-MGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQG 774
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGF---PDCAKFLTTIKCMQTIKASEH 130
+++L+ ++A + NG TA +A G+ D K +T T +H
Sbjct: 775 HTHIINVLLQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKH 832
Score = 39.3 bits (90), Expect = 0.001
Identities = 37/150 (24%), Positives = 65/150 (43%), Gaps = 6/150 (4%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL+ A+V+A + +H+A+ +G A + + GA++N Q G PL+
Sbjct: 87 VEVVSELLQREANVDAATKK-GNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLY 145
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKC-----MQT 124
AA+ LE + L+ + A L ++G T +A G L +
Sbjct: 146 MAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRLPA 205
Query: 125 IKASEHPDRNDCVAVLRQKRSLGSVENTSG 154
+ + D A+L Q + VE+ SG
Sbjct: 206 LHIAARKDDTKAAALLLQNDNNADVESKSG 235
Score = 38.5 bits (88), Expect = 0.002
Identities = 31/91 (34%), Positives = 41/91 (45%), Gaps = 1/91 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
++D LLE GA NA S VHLAA G + L A++N + G PL
Sbjct: 643 QMDIATTLLEYGADANAVTRQGIAS-VHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPL 701
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQT 99
H AA+ + +LV A +D K G T
Sbjct: 702 HLAAQEDRVNVAEVLVNQGAHVDAQTKMGYT 732
Score = 35.8 bits (81), Expect = 0.016
Identities = 32/131 (24%), Positives = 53/131 (40%), Gaps = 9/131 (6%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+H+A + L+ GA + G P+H AA +G + +S L+ A +
Sbjct: 402 TPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNT 461
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKA---------SEHPDRNDCVAVLRQK 143
N G+TA +A G + ++L KA S + D V L Q+
Sbjct: 462 TNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQ 521
Query: 144 RSLGSVENTSG 154
+ + TSG
Sbjct: 522 GASPNAATTSG 532
Score = 34.3 bits (77), Expect = 0.045
Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 17 LETGASVNAPPDPCKQS---PVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
++ G +N C Q+ +HLA+ G + LQ A+++ G LH A+
Sbjct: 61 IKNGVDINI----CNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASL 116
Query: 74 VGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASE 129
G E + +LV + A ++ ++NG T +A + KFL Q++ +
Sbjct: 117 AGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGASQSLATED 172
Score = 33.5 bits (75), Expect = 0.077
Identities = 23/84 (27%), Positives = 40/84 (47%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+H+A+ G A + L GA ++ + G PLH A+ G + + +L+ A I
Sbjct: 270 TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILS 329
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
KNG + +A +C + L
Sbjct: 330 KTKNGLSPLHMATQGDHLNCVQLL 353
Score = 31.6 bits (70), Expect = 0.29
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 3/96 (3%)
Query: 24 NAPPDPCKQS---PVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECL 80
+A PD +S P+H+AA L L GA + G PLH AAK ++
Sbjct: 588 SASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIA 647
Query: 81 SLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
+ L+ A + + G + LA G D L
Sbjct: 648 TTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLL 683
Score = 29.3 bits (64), Expect = 1.5
Identities = 37/148 (25%), Positives = 59/148 (39%), Gaps = 10/148 (6%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GAS++ +P+H+AA G LQ A + G PLH AA
Sbjct: 551 LLDHGASLSITTKK-GFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYD 609
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL---------TTIKCMQTIK 126
+ + LL+ A KNG T +A D A L T + + ++
Sbjct: 610 NQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVH 669
Query: 127 ASEHPDRNDCVAVLRQKRSLGSVENTSG 154
+ D V++L + + ++ N SG
Sbjct: 670 LAAQEGHVDMVSLLLGRNANVNLSNKSG 697
Score = 26.9 bits (58), Expect = 7.3
Identities = 13/35 (37%), Positives = 20/35 (57%)
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
+AA+ G LE + + I++CN+NG A LA
Sbjct: 47 RAARAGHLEKALDYIKNGVDINICNQNGLNALHLA 81
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo
sapiens]
Length = 2603
Score = 50.4 bits (119), Expect = 6e-07
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA L + + G PL
Sbjct: 447 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLM 505
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+ A I+ + Q TA LA GF + A FL
Sbjct: 506 EAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 553
Score = 47.4 bits (111), Expect = 5e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 16 LLETGASVNAPPDPC-KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
LL+ GA VNAPP P + + + +AA G F + GA ++ ++ G PL AA
Sbjct: 1304 LLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 1363
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRN 134
G L+ + LLV + A +D + T A+ G ++L + ++ P +
Sbjct: 1364 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK-------EVNQFPSDS 1416
Query: 135 DCVAVLRQKRSLGSVENTSGKRKC 158
+C+ R + ++ + +KC
Sbjct: 1417 ECM------RYIATITDKEMLKKC 1434
Score = 42.4 bits (98), Expect = 2e-04
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + ++ GAD+ LG PL +AA+
Sbjct: 519 LLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIE----LGCSTPLMEAAQE 574
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+A+ A + G TA A G D A L
Sbjct: 575 GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 616
Score = 37.7 bits (86), Expect = 0.004
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LLE GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 380 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALM 439
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 440 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 477
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/76 (28%), Positives = 38/76 (50%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GA + A + K +P+ LA G + L GA+ ++V PL AA G
Sbjct: 1135 LLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGG 1194
Query: 76 SLECLSLLVASDAQID 91
+ + +L+ + A+I+
Sbjct: 1195 YVNIIKILLNAGAEIN 1210
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/84 (30%), Positives = 39/84 (46%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ AA G + L AD+N Q G L A G ++ + +L+ S A I+
Sbjct: 303 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 362
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 363 HNENGHTPLMEAGSAGHVEVARLL 386
Score = 35.8 bits (81), Expect = 0.016
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K+LL GA+V+A + + A +G LQ GADL + G PL KAA
Sbjct: 580 VKYLLAAGANVHATT-ATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAA 638
Query: 73 KVGSLECLSLLVASDAQIDLCNKN 96
+ G + + L++ A ++ N
Sbjct: 639 RAGHVCTVQFLISKGANVNRTTAN 662
Score = 34.3 bits (77), Expect = 0.045
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K LL A VNA + + AG G + L++GA + + G PL +A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAG-GYVDVVKVLLESGASIEDHNENGHTPLMEAG 375
Query: 73 KVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASE 129
G +E LL+ + A I+ N+ ++A LA G + +FL Q K E
Sbjct: 376 SAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Score = 34.3 bits (77), Expect = 0.045
Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Query: 10 VDGLKHLLETGASVNAPP-DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQ-DVLGEAP 67
V+ +K LL GA +N+ SP+ LAA +G + L G+D+N Q +
Sbjct: 1196 VNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTA 1255
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
L A G E +SLL+ A ++ K G T A S G+ + + L
Sbjct: 1256 LTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1304
Score = 28.9 bits (63), Expect = 1.9
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQ--DVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
+P+ LAA G + L GA++N + LG +PL AA G + LL+ + I
Sbjct: 1185 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 1244
Query: 91 DL-CNKNGQTAEDLA 104
+ N TA LA
Sbjct: 1245 NAQIETNRNTALTLA 1259
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo
sapiens]
Length = 2352
Score = 50.4 bits (119), Expect = 6e-07
Identities = 39/108 (36%), Positives = 57/108 (52%), Gaps = 2/108 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LL++GA VN P D +SP+ LAA G ++ GA L + + G PL
Sbjct: 447 VEVARLLLDSGAQVNMPADSF-ESPLTLAACGGHVELAALLIERGASLEEVNDEGYTPLM 505
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQ-TAEDLAWSCGFPDCAKFL 116
+AA+ G E ++LL+ A I+ + Q TA LA GF + A FL
Sbjct: 506 EAAREGHEEMVALLLGQGANINAQTEETQETALTLACCGGFLEVADFL 553
Score = 47.4 bits (111), Expect = 5e-06
Identities = 37/144 (25%), Positives = 66/144 (45%), Gaps = 14/144 (9%)
Query: 16 LLETGASVNAPPDPC-KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
LL+ GA VNAPP P + + + +AA G F + GA ++ ++ G PL AA
Sbjct: 1053 LLDKGADVNAPPVPSSRDTALTIAADKGHYKFCELLIGRGAHIDVRNKKGNTPLWLAANG 1112
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRN 134
G L+ + LLV + A +D + T A+ G ++L + ++ P +
Sbjct: 1113 GHLDVVQLLVQAGADVDAADNRKITPLMAAFRKGHVKVVRYLVK-------EVNQFPSDS 1165
Query: 135 DCVAVLRQKRSLGSVENTSGKRKC 158
+C+ R + ++ + +KC
Sbjct: 1166 ECM------RYIATITDKEMLKKC 1183
Score = 42.4 bits (98), Expect = 2e-04
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLG-EAPLHKAAKV 74
LL GA++NA + +++ + LA G + ++ GAD+ LG PL +AA+
Sbjct: 519 LLGQGANINAQTEETQETALTLACCGGFLEVADFLIKAGADIE----LGCSTPLMEAAQE 574
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
G LE + L+A+ A + G TA A G D A L
Sbjct: 575 GHLELVKYLLAAGANVHATTATGDTALTYACENGHTDVADVL 616
Score = 37.7 bits (86), Expect = 0.004
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V+ + LLE GA +N + K+S + LA G + + L+ GAD + L
Sbjct: 380 VEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDEMHTALM 439
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
+A G +E LL+ S AQ+++ + ++ LA +CG
Sbjct: 440 EACMDGHVEVARLLLDSGAQVNMPADSFESPLTLA-ACG 477
Score = 37.0 bits (84), Expect = 0.007
Identities = 22/76 (28%), Positives = 38/76 (50%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GA + A + K +P+ LA G + L GA+ ++V PL AA G
Sbjct: 884 LLDNGADIEAQSERTKDTPLSLACSGGRQEVVELLLARGANKEHRNVSDYTPLSLAASGG 943
Query: 76 SLECLSLLVASDAQID 91
+ + +L+ + A+I+
Sbjct: 944 YVNIIKILLNAGAEIN 959
Score = 36.6 bits (83), Expect = 0.009
Identities = 26/84 (30%), Positives = 39/84 (46%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+ AA G + L AD+N Q G L A G ++ + +L+ S A I+
Sbjct: 303 TPLMAAANGGHVKIVKLLLAHKADVNAQSSTGNTALTYACAGGYVDVVKVLLESGASIED 362
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFL 116
N+NG T A S G + A+ L
Sbjct: 363 HNENGHTPLMEAGSAGHVEVARLL 386
Score = 35.8 bits (81), Expect = 0.016
Identities = 25/84 (29%), Positives = 40/84 (47%), Gaps = 1/84 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K+LL GA+V+A + + A +G LQ GADL + G PL KAA
Sbjct: 580 VKYLLAAGANVHATT-ATGDTALTYACENGHTDVADVLLQAGADLEHESEGGRTPLMKAA 638
Query: 73 KVGSLECLSLLVASDAQIDLCNKN 96
+ G + + L++ A ++ N
Sbjct: 639 RAGHVCTVQFLISKGANVNRTTAN 662
Score = 34.3 bits (77), Expect = 0.045
Identities = 33/118 (27%), Positives = 51/118 (43%), Gaps = 2/118 (1%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
+K LL A VNA + + AG G + L++GA + + G PL +A
Sbjct: 317 VKLLLAHKADVNAQSSTGNTALTYACAG-GYVDVVKVLLESGASIEDHNENGHTPLMEAG 375
Query: 73 KVGSLECLSLLVASDAQIDL-CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASE 129
G +E LL+ + A I+ N+ ++A LA G + +FL Q K E
Sbjct: 376 SAGHVEVARLLLENGAGINTHSNEFKESALTLACYKGHLEMVRFLLEAGADQEHKTDE 433
Score = 34.3 bits (77), Expect = 0.045
Identities = 33/109 (30%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Query: 10 VDGLKHLLETGASVNAPP-DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQ-DVLGEAP 67
V+ +K LL GA +N+ SP+ LAA +G + L G+D+N Q +
Sbjct: 945 VNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDINAQIETNRNTA 1004
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
L A G E +SLL+ A ++ K G T A S G+ + + L
Sbjct: 1005 LTLACFQGRTEVVSLLLDRKANVEHRAKTGLTPLMEAASGGYAEVGRVL 1053
Score = 28.9 bits (63), Expect = 1.9
Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQ--DVLGEAPLHKAAKVGSLECLSLLVASDAQI 90
+P+ LAA G + L GA++N + LG +PL AA G + LL+ + I
Sbjct: 934 TPLSLAASGGYVNIIKILLNAGAEINSRTGSKLGISPLMLAAMNGHTAAVKLLLDMGSDI 993
Query: 91 DL-CNKNGQTAEDLA 104
+ N TA LA
Sbjct: 994 NAQIETNRNTALTLA 1008
>gi|55742857 ankyrin repeat domain 6 [Homo sapiens]
Length = 722
Score = 50.1 bits (118), Expect = 8e-07
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+ + + L+ GA V ++P+HLAA G + L+ G DL+ QD + L
Sbjct: 22 QTENVVQLINKGARVAVTKHG--RTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTAL 79
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
H+A VG+ E ++ L+ +D +K+G TA A GF AK L
Sbjct: 80 HRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLL 127
Score = 37.4 bits (85), Expect = 0.005
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ G ++ D Q+ +H A G + + G L++QD G LH+A+ G
Sbjct: 61 LLKAGCDLDVQDDG-DQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHG 119
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLA 104
+ LLV + A + NK G TA LA
Sbjct: 120 FSQSAKLLVKAGANVLAKNKAGNTALHLA 148
Score = 31.2 bits (69), Expect = 0.38
Identities = 27/115 (23%), Positives = 49/115 (42%), Gaps = 2/115 (1%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H+AA + L +++++ G+ LH AA + + +L+ + A + N
Sbjct: 178 LHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVN 237
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRNDCVAVLRQKRSLGSV 149
GQT + A P+ A LT K Q ++ S L+++R SV
Sbjct: 238 NAGQTPLETARYHNNPEVALLLT--KAPQVLRFSRGRSLRKKRERLKEERRAQSV 290
Score = 26.6 bits (57), Expect = 9.5
Identities = 19/87 (21%), Positives = 37/87 (42%)
Query: 35 VHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDLCN 94
+H A+ G + ++ GA++ ++ G LH A + + +L+ + ++ DL N
Sbjct: 112 LHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKN 171
Query: 95 KNGQTAEDLAWSCGFPDCAKFLTTIKC 121
G T +A + L T C
Sbjct: 172 NAGDTCLHVAARYNHLSIIRLLLTAFC 198
>gi|41327752 diabetes related ankyrin repeat protein [Homo sapiens]
Length = 305
Score = 50.1 bits (118), Expect = 8e-07
Identities = 35/98 (35%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
Query: 13 LKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAA 72
LK LL GA VNA D +P+H+A + L ++ GA LN QD G+ LH+A
Sbjct: 193 LKQLLNQGARVNAR-DKIGSTPLHVAVRTRHPDCLEHLIECGAHLNAQDKEGDTALHEAV 251
Query: 73 KVGSLECLSLLVASDAQIDLCNKNGQTAEDLA--WSCG 108
+ GS + + LL+ A++ + N T LA W G
Sbjct: 252 RHGSYKAMKLLLLYGAELGVRNAASVTPVQLARDWQRG 289
Score = 47.4 bits (111), Expect = 5e-06
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL GA+V+A D ++PV A G L L GA +N +D +G PLH A +
Sbjct: 163 LLVAGATVDAR-DLLDRTPVFWACRGGHLVILKQLLNQGARVNARDKIGSTPLHVAVRTR 221
Query: 76 SLECLSLLVASDAQIDLCNKNGQTA 100
+CL L+ A ++ +K G TA
Sbjct: 222 HPDCLEHLIECGAHLNAQDKEGDTA 246
Score = 37.7 bits (86), Expect = 0.004
Identities = 31/113 (27%), Positives = 52/113 (46%), Gaps = 3/113 (2%)
Query: 17 LETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGS 76
L G NA D ++ +H A G + + L GA ++ +D+L P+ A + G
Sbjct: 131 LTDGGDPNAH-DKLHRTALHWACLKGHSQLVNKLLVAGATVDARDLLDRTPVFWACRGGH 189
Query: 77 LECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASE 129
L L L+ A+++ +K G T +A PDC + L I+C + A +
Sbjct: 190 LVILKQLLNQGARVNARDKIGSTPLHVAVRTRHPDCLEHL--IECGAHLNAQD 240
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 50.1 bits (118), Expect = 8e-07
Identities = 33/98 (33%), Positives = 53/98 (54%), Gaps = 1/98 (1%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPL 68
+V+ ++ LLE GA A D + + +H A+ +G + L GAD NQ+D LG PL
Sbjct: 122 DVETVQQLLEDGADPCAADDKGRTA-LHFASCNGNDQIVQLLLDHGADPNQRDGLGNTPL 180
Query: 69 HKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWS 106
H AA + ++ L+ A++D ++ G+T LA S
Sbjct: 181 HLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKS 218
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 49.7 bits (117), Expect = 1e-06
Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 11 DGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHK 70
D ++HLL+ GA+V+A D P+H A G A + L GAD N +D PLH+
Sbjct: 230 DVVEHLLQMGANVHARDDG-GLIPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHE 288
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
AA G ++ +L+ A ++ N +G++A DLA
Sbjct: 289 AAIKGKIDVCIVLLQHGADPNIRNTDGKSALDLA 322
Score = 47.4 bits (111), Expect = 5e-06
Identities = 33/91 (36%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 14 KHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
++LLE GA VNA D P+H AA G ++ +N D PLH+AA+
Sbjct: 854 EYLLEHGADVNAQ-DKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAAQ 912
Query: 74 VGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
G + +LL+A A + N+ GQT DLA
Sbjct: 913 KGRTQLCALLLAHGADPTMKNQEGQTPLDLA 943
Score = 45.4 bits (106), Expect = 2e-05
Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPC-KQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGE 65
N +V +K L++ A+VNA K SP+H AAG G + LQ GA+++ +D G
Sbjct: 192 NGDVSRVKRLVDA-ANVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGANVHARDDGGL 250
Query: 66 APLHKAAKVGSLECLSLLVASDA 88
PLH A G E +SLL+ A
Sbjct: 251 IPLHNACSFGHAEVVSLLLCQGA 273
Score = 43.1 bits (100), Expect = 1e-04
Identities = 23/63 (36%), Positives = 36/63 (57%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+HLAAG + L+ GAD+N QD G PLH AA G ++ +LL+ + ++
Sbjct: 839 TPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNA 898
Query: 93 CNK 95
+K
Sbjct: 899 TDK 901
Score = 42.7 bits (99), Expect = 1e-04
Identities = 32/89 (35%), Positives = 46/89 (51%), Gaps = 1/89 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GA V+A D P+H A G L+ GA +N D+ PLH+AA
Sbjct: 388 LLQHGADVHAK-DKGGLVPLHNACSYGHYEVTELLLKHGACVNAMDLWQFTPLHEAASKN 446
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLA 104
+E SLL++ A L N +G++A D+A
Sbjct: 447 RVEVCSLLLSHGADPTLVNCHGKSAVDMA 475
Score = 42.0 bits (97), Expect = 2e-04
Identities = 24/64 (37%), Positives = 33/64 (51%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D K +P+HLAAG + LQ GAD++ +D G PLH A G E LL+
Sbjct: 366 DGRKSTPLHLAAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG 425
Query: 88 AQID 91
A ++
Sbjct: 426 ACVN 429
Score = 40.8 bits (94), Expect = 5e-04
Identities = 21/62 (33%), Positives = 32/62 (51%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+H AAG + + L GAD++ +D G PLH A G E LLV A +++
Sbjct: 686 TPLHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNV 745
Query: 93 CN 94
+
Sbjct: 746 AD 747
Score = 39.3 bits (90), Expect = 0.001
Identities = 31/94 (32%), Positives = 44/94 (46%), Gaps = 1/94 (1%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V +++LL GA V+A D P+H A G ++ GA +N D+ PLH
Sbjct: 697 VSVVEYLLHHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLH 755
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDL 103
+AA G E LL+ A N++G T DL
Sbjct: 756 EAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDL 789
Score = 38.9 bits (89), Expect = 0.002
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL GA+VN +P+H+AA + + GA +N D LG+ LH+AA G
Sbjct: 544 LLRKGANVNEKNKDF-MTPLHVAAERAHNDVMEVLHKHGAKMNALDTLGQTALHRAALAG 602
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDL 103
L+ LL++ + + + G TA +
Sbjct: 603 HLQTCRLLLSYGSDPSIISLQGFTAAQM 630
Score = 28.5 bits (62), Expect = 2.5
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 50 QLQTGADLNQQDVLGE--APLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSC 107
+L T ++N +D G PLH AA +LE L+ A ++ +K G A S
Sbjct: 821 KLCTPENINCRDTQGRNSTPLHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASY 880
Query: 108 GFPDCAKFL 116
G D A L
Sbjct: 881 GHVDIAALL 889
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 49.7 bits (117), Expect = 1e-06
Identities = 34/94 (36%), Positives = 52/94 (55%), Gaps = 1/94 (1%)
Query: 11 DGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHK 70
D +++LL+ GA+V A D P+H A G A + L+ GAD N +D PLH+
Sbjct: 72 DVVEYLLQNGANVQARDDG-GLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHE 130
Query: 71 AAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLA 104
AA G ++ +L+ A+ + N +G+TA DLA
Sbjct: 131 AAIKGKIDVCIVLLQHGAEPTIRNTDGRTALDLA 164
Score = 46.6 bits (109), Expect = 9e-06
Identities = 33/90 (36%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 14 KHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
++LL+ GA VNA D P+H AA G ++ A +N D PLH+AA+
Sbjct: 696 EYLLQHGADVNAQ-DKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQ 754
Query: 74 VGSLECLSLLVASDAQIDLCNKNGQTAEDL 103
G + +LL+A A L N+ GQT DL
Sbjct: 755 KGRTQLCALLLAHGADPTLKNQEGQTPLDL 784
Score = 45.8 bits (107), Expect = 2e-05
Identities = 25/63 (39%), Positives = 37/63 (58%)
Query: 33 SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
+P+HLAAG + LQ GAD+N QD G PLH AA G ++ +LL+ +A ++
Sbjct: 681 TPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA 740
Query: 93 CNK 95
+K
Sbjct: 741 TDK 743
Score = 43.9 bits (102), Expect = 6e-05
Identities = 31/87 (35%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 9 EVDGLKHLLETGASVNAPPDPCKQS-PVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAP 67
+V+ +K L T SVN +QS P+H AAG + + LQ GAD++ +D G P
Sbjct: 504 DVETVKKLC-TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVP 562
Query: 68 LHKAAKVGSLECLSLLVASDAQIDLCN 94
LH A G E LLV A +++ +
Sbjct: 563 LHNACSYGHYEVAELLVKHGAVVNVAD 589
Score = 42.4 bits (98), Expect = 2e-04
Identities = 29/83 (34%), Positives = 45/83 (54%), Gaps = 2/83 (2%)
Query: 7 NPEVDGLKHLLETGASVNAPPDPCKQS-PVHLAAGSGLACFLLWQLQTGADLNQQDVLGE 65
N +V+ +K L+ T VN+ ++S P+H AAG G + + LQ GA++ +D G
Sbjct: 34 NGDVERVKRLV-TPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGL 92
Query: 66 APLHKAAKVGSLECLSLLVASDA 88
PLH A G E ++LL+ A
Sbjct: 93 IPLHNACSFGHAEVVNLLLRHGA 115
Score = 40.4 bits (93), Expect = 6e-04
Identities = 24/64 (37%), Positives = 32/64 (50%)
Query: 28 DPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVASD 87
D K +P+HLAAG + LQ GAD++ +D PLH A G E LLV
Sbjct: 208 DGRKSTPLHLAAGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHG 267
Query: 88 AQID 91
A ++
Sbjct: 268 ACVN 271
Score = 40.4 bits (93), Expect = 6e-04
Identities = 41/136 (30%), Positives = 58/136 (42%), Gaps = 11/136 (8%)
Query: 10 VDGLKHLLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLH 69
V +++LL+ GA V+A D P+H A G ++ GA +N D+ PLH
Sbjct: 539 VSVVEYLLQHGADVHAK-DKGGLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLH 597
Query: 70 KAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDC-------AKFLTTIK-- 120
+AA G E LL+ A N++G T DL G D A L K
Sbjct: 598 EAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLV-KDGDTDIQDLLRGDAALLDAAKKG 656
Query: 121 CMQTIKASEHPDRNDC 136
C+ +K PD +C
Sbjct: 657 CLARVKKLSSPDNVNC 672
Score = 39.7 bits (91), Expect = 0.001
Identities = 31/89 (34%), Positives = 45/89 (50%), Gaps = 1/89 (1%)
Query: 16 LLETGASVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
LL+ GA V+A D P+H A G ++ GA +N D+ PLH+AA
Sbjct: 230 LLQHGADVHAK-DKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKN 288
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLA 104
+E SLL++ A L N + ++A DLA
Sbjct: 289 RVEVCSLLLSYGADPTLLNCHNKSAIDLA 317
Score = 35.4 bits (80), Expect = 0.020
Identities = 27/104 (25%), Positives = 49/104 (47%), Gaps = 7/104 (6%)
Query: 23 VNAPPDPCKQSPVHLAAGSGLA-----CFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSL 77
VN ++ +H AA S C LL L+ GA++N++ PLH A++
Sbjct: 356 VNFKHPQTHETALHCAAASPYPKRKQICELL--LRKGANINEKTKEFLTPLHVASEKAHN 413
Query: 78 ECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKC 121
+ + ++V +A+++ + GQT+ A CG + L + C
Sbjct: 414 DVVEVVVKHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGC 457
Score = 33.5 bits (75), Expect = 0.077
Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 16 LLETGASVNAPPDPCKQ--SPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAK 73
LL GA++N + K+ +P+H+A+ + ++ A +N D LG+ LH+AA
Sbjct: 386 LLRKGANIN---EKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAY 442
Query: 74 VGSLECLSLLVASDAQIDLCNKNGQTA 100
G L+ LL++ ++ + G TA
Sbjct: 443 CGHLQTCRLLLSYGCDPNIISLQGFTA 469
Score = 27.3 bits (59), Expect = 5.6
Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Query: 50 QLQTGADLNQQDVLGE--APLHKAAKVGSLECLSLLVASDAQIDLCNKNGQTAEDLAWSC 107
+L + ++N +D G PLH AA +LE L+ A ++ +K G A S
Sbjct: 663 KLSSPDNVNCRDTQGRHSTPLHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASY 722
Query: 108 GFPDCAKFL 116
G D A L
Sbjct: 723 GHVDVAALL 731
>gi|169403959 ankyrin repeat domain 53 isoform a [Homo sapiens]
Length = 530
Score = 49.7 bits (117), Expect = 1e-06
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 32 QSPVHLAAGS-----GLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVAS 86
Q+P+HL L C + + L+ GADLN Q G PLH AA+ G L+C+ +LV S
Sbjct: 175 QTPLHLVIHRDNTTVALPC-IYYLLEKGADLNAQTCNGSTPLHLAARDGLLDCVKVLVQS 233
Query: 87 DAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
A + + G D CA+FL
Sbjct: 234 GANVHAQDAMGYKPIDFCKIWNHRACARFL 263
>gi|169403957 ankyrin repeat domain 53 isoform b [Homo sapiens]
Length = 343
Score = 49.7 bits (117), Expect = 1e-06
Identities = 32/90 (35%), Positives = 44/90 (48%), Gaps = 6/90 (6%)
Query: 32 QSPVHLAAGS-----GLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVGSLECLSLLVAS 86
Q+P+HL L C + + L+ GADLN Q G PLH AA+ G L+C+ +LV S
Sbjct: 175 QTPLHLVIHRDNTTVALPC-IYYLLEKGADLNAQTCNGSTPLHLAARDGLLDCVKVLVQS 233
Query: 87 DAQIDLCNKNGQTAEDLAWSCGFPDCAKFL 116
A + + G D CA+FL
Sbjct: 234 GANVHAQDAMGYKPIDFCKIWNHRACARFL 263
>gi|116325987 ankyrin repeat domain 42 [Homo sapiens]
Length = 389
Score = 49.7 bits (117), Expect = 1e-06
Identities = 43/129 (33%), Positives = 58/129 (44%), Gaps = 3/129 (2%)
Query: 16 LLETGASVNAPPDP-CKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKV 74
L+ GA++ A D C +P+HLAA G + L L++G D + D P+H AA
Sbjct: 84 LIMNGANLTAQDDRGC--TPLHLAATHGHSFTLQIMLRSGVDPSVTDKREWRPVHYAAFH 141
Query: 75 GSLECLSLLVASDAQIDLCNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRN 134
G L CL LLV I+ + NG LA G C KFL + T D
Sbjct: 142 GRLGCLQLLVKWGCSIEDVDYNGNLPVHLAAMEGHLHCFKFLVSRMSSATQVLKAFNDNG 201
Query: 135 DCVAVLRQK 143
+ V L Q+
Sbjct: 202 ENVLDLAQR 210
Score = 44.7 bits (104), Expect = 3e-05
Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 7/103 (6%)
Query: 34 PVHLAAGSGLACFLLWQLQTGA-DLNQQDVLGEAPLHKAAKVGSLECLSLLVASDAQIDL 92
P H+AA G L ++ G ++N++ G P+HKAA G +ECL L+ A ++
Sbjct: 239 PGHVAAFKGDLGMLKKLVEDGVININERADNGSTPMHKAAGQGHIECLQWLIKMGADSNI 298
Query: 93 CNKNGQTAEDLAWSCGFPDCAKFLTTIKCMQTIKASEHPDRND 135
NK G+ D+A L +K ++ ++ + D N+
Sbjct: 299 TNKAGERPSDVAKRFA------HLAAVKLLEELQKYDIDDENE 335
Score = 37.7 bits (86), Expect = 0.004
Identities = 26/72 (36%), Positives = 36/72 (50%), Gaps = 2/72 (2%)
Query: 13 LKHLLETGA-SVNAPPDPCKQSPVHLAAGSGLACFLLWQLQTGADLNQQDVLGEAPLHKA 71
LK L+E G ++N D +P+H AAG G L W ++ GAD N + GE P A
Sbjct: 252 LKKLVEDGVININERADN-GSTPMHKAAGQGHIECLQWLIKMGADSNITNKAGERPSDVA 310
Query: 72 AKVGSLECLSLL 83
+ L + LL
Sbjct: 311 KRFAHLAAVKLL 322
Score = 29.6 bits (65), Expect = 1.1
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 13/93 (13%)
Query: 28 DPCKQSPVHLA-------AG-----SGLACFLLWQLQTGADLNQQDVLGEAPLHKAAKVG 75
+PC + VH AG S + C L W L GAD+ G H AA G
Sbjct: 18 NPCSRKKVHFGSIHDAVRAGDVKQLSEIVC-LHWLLWHGADITHVTTRGWTASHIAAIRG 76
Query: 76 SLECLSLLVASDAQIDLCNKNGQTAEDLAWSCG 108
C+ L+ + A + + G T LA + G
Sbjct: 77 QDACVQALIMNGANLTAQDDRGCTPLHLAATHG 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,683,699
Number of Sequences: 37866
Number of extensions: 296560
Number of successful extensions: 2034
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 306
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 642
Number of HSP's gapped (non-prelim): 1244
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.