Guide to the Human Genome
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Search of human proteins with 31795546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31795546 solute carrier family 13 (sodium/sulfate
symporters), member 4 [Homo sapiens]
         (626 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31795546 solute carrier family 13 (sodium/sulfate symporters)...  1261   0.0  
gi|19923838 solute carrier family 13 (sodium/sulfate symporters)...   585   e-167
gi|29171306 solute carrier family 13, member 5 isoform a [Homo s...   484   e-136
gi|4506979 solute carrier family 13, member 2 isoform b [Homo sa...   477   e-134
gi|225637549 solute carrier family 13, member 2 isoform a [Homo ...   454   e-127
gi|31377715 solute carrier family 13 member 3 isoform a [Homo sa...   451   e-127
gi|58761541 solute carrier family 13 member 3 isoform b [Homo sa...   427   e-119
gi|225637552 solute carrier family 13, member 2 isoform c [Homo ...   412   e-115
gi|219802232 solute carrier family 13, member 5 isoform b [Homo ...   405   e-113
gi|157266326 oculocutaneous albinism II [Homo sapiens]                 56   1e-07
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    35   0.16 
gi|13677214 receptor-type protein tyrosine phosphatase O isoform...    33   0.79 
gi|4506323 receptor-type protein tyrosine phosphatase O isoform ...    33   0.79 
gi|25282469 retinol dehydrogenase 10 [Homo sapiens]                    33   0.79 
gi|40217829 G protein-coupled receptor 68 [Homo sapiens]               33   1.0  
gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]      32   1.8  
gi|54606888 hypothetical protein LOC23251 [Homo sapiens]               32   2.3  
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    32   2.3  
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    32   2.3  
gi|56676335 RAP1 interacting factor 1 [Homo sapiens]                   32   2.3  
gi|188497642 ARHGAP15 [Homo sapiens]                                   31   3.0  
gi|104526627 triadin [Homo sapiens]                                    31   3.0  
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom...    31   3.9  
gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Hom...    31   3.9  
gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo...    31   3.9  
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]           31   3.9  
gi|5174593 melatonin receptor 1A [Homo sapiens]                        30   5.1  
gi|24475869 cellular repressor of E1A-stimulated genes 2 [Homo s...    30   5.1  
gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens]          30   6.7  
gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs...    30   8.7  

>gi|31795546 solute carrier family 13 (sodium/sulfate symporters),
           member 4 [Homo sapiens]
          Length = 626

 Score = 1261 bits (3264), Expect = 0.0
 Identities = 626/626 (100%), Positives = 626/626 (100%)

Query: 1   MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAAL 60
           MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAAL
Sbjct: 1   MGLLQGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAAL 60

Query: 61  VPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKP 120
           VPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKP
Sbjct: 61  VPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKP 120

Query: 121 GMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPIS 180
           GMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPIS
Sbjct: 121 GMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPIS 180

Query: 181 LDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKP 240
           LDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKP
Sbjct: 181 LDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKP 240

Query: 241 QVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQ 300
           QVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQ
Sbjct: 241 QVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQ 300

Query: 301 YPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEK 360
           YPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEK
Sbjct: 301 YPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEK 360

Query: 361 RIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFL 420
           RIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFL
Sbjct: 361 RIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFL 420

Query: 421 GFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGS 480
           GFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGS
Sbjct: 421 GFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGS 480

Query: 481 KSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH 540
           KSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH
Sbjct: 481 KSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH 540

Query: 541 INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI 600
           INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI
Sbjct: 541 INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI 600

Query: 601 NTWGVSLFHLDTYPAWARVSNITDQA 626
           NTWGVSLFHLDTYPAWARVSNITDQA
Sbjct: 601 NTWGVSLFHLDTYPAWARVSNITDQA 626


>gi|19923838 solute carrier family 13 (sodium/sulfate symporters),
           member 1 [Homo sapiens]
          Length = 595

 Score =  585 bits (1509), Expect = e-167
 Identities = 300/612 (49%), Positives = 406/612 (66%), Gaps = 33/612 (5%)

Query: 7   LLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLY 66
           +L  R+ L VV   L+LLPLP++  + EA CAY L V A +W++EA+PL   AL+P+ + 
Sbjct: 7   ILVYRRFLFVVFTVLVLLPLPIVLHTKEAECAYTLFVVATFWLTEALPLSVTALLPSLML 66

Query: 67  PFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLC 126
           P FG++ S +VA+ YFK+  LLL+GVIC+A ++EKWNLHKRIAL+MV+M G  P  L L 
Sbjct: 67  PMFGIMPSKKVASAYFKDFHLLLIGVICLATSIEKWNLHKRIALKMVMMVGVNPAWLTLG 126

Query: 127 FMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNS 186
           FM  T  LSMWLSNTST AMVMPI EAV+Q++++AE E          EA  ++    ++
Sbjct: 127 FMSSTAFLSMWLSNTSTAAMVMPIAEAVVQQIINAEAEV---------EATQMTYFNGST 177

Query: 187 QPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPS 246
              LE+    +ES       ++   +N     T P+   N   GK     + +       
Sbjct: 178 NHGLEI----DES-------VNGHEINERKEKTKPVPGYNNDTGKISSKVELE------- 219

Query: 247 PRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEV 306
            +   +  KYR+    +  K   L I+YS+TIGGLTTI GTST+LIF E+FN +YP    
Sbjct: 220 -KNSGMRTKYRTKKGHVTRKLTCLCIAYSSTIGGLTTITGTSTNLIFAEYFNTRYPDCRC 278

Query: 307 VNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEY 366
           +NFG+WF FSFP +LI+L++SW W+ WLFLG NFKE     K K  +++  +E  I++EY
Sbjct: 279 LNFGSWFTFSFPAALIILLLSWIWLQWLFLGFNFKEMFKCGKTKTVQQKACAEV-IKQEY 337

Query: 367 EKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFF-EKKGYRTDATVSVFLGFLLF 425
           +KLG I Y E+VT   FI+M +LWF+R+PGFVPGW + F E  G+ TD+TV++ +G L F
Sbjct: 338 QKLGPIRYQEIVTLVLFIIMALLWFSRDPGFVPGWSALFSEYPGFATDSTVALLIGLLFF 397

Query: 426 LIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGL 485
           LIPAK      K     +  +    P+ITWK+FQ  MPW+I ILVGGG+ALA G + SGL
Sbjct: 398 LIPAKTLT---KTTPTGEIVAFDYSPLITWKEFQSFMPWDIAILVGGGFALADGCEESGL 454

Query: 486 STWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLY 545
           S WIGN++  L SLP W + L++ ++V+ +TE  SNPATIT+FLPIL  L+E +H+NPLY
Sbjct: 455 SKWIGNKLSPLGSLPAWLIILISSLMVTSLTEVASNPATITLFLPILSPLAEAIHVNPLY 514

Query: 546 TLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGV 605
            LIP T+C SFA +LPV NPPNAIVFSYGH ++ DMVKAGLGVN++G+ +VM+ I TW V
Sbjct: 515 ILIPSTLCTSFAFLLPVANPPNAIVFSYGHLKVIDMVKAGLGVNIVGVAVVMLGICTWIV 574

Query: 606 SLFHLDTYPAWA 617
            +F L TYP+WA
Sbjct: 575 PMFDLYTYPSWA 586


>gi|29171306 solute carrier family 13, member 5 isoform a [Homo
           sapiens]
          Length = 568

 Score =  484 bits (1245), Expect = e-136
 Identities = 256/622 (41%), Positives = 384/622 (61%), Gaps = 73/622 (11%)

Query: 9   RVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPF 68
           + +  +++   PLLLLPL +L P+    CAYV+I+ A+YW +E +PL   +L+P  L+P 
Sbjct: 10  KFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPL 69

Query: 69  FGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFM 128
           F +L S +V  +Y K+T +L +G + VA AVE+WNLHKRIALR +L  GAKP  L+L FM
Sbjct: 70  FQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFM 129

Query: 129 CCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQP 188
             T LLSMW+SNT+TTAM++PIVEA+LQ        Q+ A ++ TE              
Sbjct: 130 GVTALLSMWISNTATTAMMVPIVEAILQ--------QMEATSAATEAG------------ 169

Query: 189 SLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGK-KQHPSQEKPQVLTPSP 247
            LEL+                                   +GK K+ P     QV+   P
Sbjct: 170 -LELV----------------------------------DKGKAKELPGS---QVIFEGP 191

Query: 248 RKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYP-AAEV 306
              +   + R      +CK ++L I Y+A+IGG  T+ GT  +++ L   N  +P + ++
Sbjct: 192 TLGQQEDQERKR----LCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDL 247

Query: 307 VNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKET--CSLSKKKKTKREQLSEKRIQE 364
           VNF +WF F+FP  L+ML+ +W W+ ++++  NFK++  C L  KK    E+ + K +QE
Sbjct: 248 VNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKN---EKAALKVLQE 304

Query: 365 EYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKG---YRTDATVSVFLG 421
           EY KLG +S+ E+     F L+ +LWF+R+PGF+PGW +    +G   Y +DATV++F+ 
Sbjct: 305 EYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVA 364

Query: 422 FLLFLIPAKKPCFGKKNDGENQEHS-LGTEPIITWKDFQKTMPWEIVILVGGGYALASGS 480
            LLF++P++KP F  ++  E +  +     P++ WK  Q+ +PW IV+L+GGG+ALA GS
Sbjct: 365 TLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGS 424

Query: 481 KSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH 540
           ++SGLS W+G QM  L ++PP A+TL+  +LV++ TE  SN AT T+FLPI  S+S ++ 
Sbjct: 425 EASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIG 484

Query: 541 INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI 600
           +NPLY ++P T+  SFA MLPV  PPNAIVF+YGH ++ DMVK G+ +N+IG+  V +A+
Sbjct: 485 LNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAV 544

Query: 601 NTWGVSLFHLDTYPAWARVSNI 622
           NTWG ++F LD +P WA V++I
Sbjct: 545 NTWGRAIFDLDHFPDWANVTHI 566


>gi|4506979 solute carrier family 13, member 2 isoform b [Homo
           sapiens]
          Length = 592

 Score =  477 bits (1228), Expect = e-134
 Identities = 257/626 (41%), Positives = 382/626 (61%), Gaps = 57/626 (9%)

Query: 5   QGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAF 64
           Q L   R  L+V  VP+LLLPLP+L PS EA CAY +I+ A++W +EA+PL   AL P  
Sbjct: 6   QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLI 65

Query: 65  LYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLL 124
           L+P  G++ ++EVA EY K++ LL  G + VA AVE WNLHKRIALR++L+ G +P  L+
Sbjct: 66  LFPMMGIVDASEVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLI 125

Query: 125 LCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVK 184
           L FM  T  LSMW+SNT+T+AM++PI  AVL +L S++       +SN EE         
Sbjct: 126 LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQ------ASSNVEEG-------- 171

Query: 185 NSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLT 244
           ++ P+ EL    E S     T + N                           Q  P    
Sbjct: 172 SNNPTFEL---QEPSPQKEVTKLDN--------------------------GQALPVTSA 202

Query: 245 PSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPA- 303
            S  +  L++K+       + +C+SL + YSA+IGG+ T+ GT+ +L+     N+ +P  
Sbjct: 203 SSEGRAHLSQKHLH-----LTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQN 257

Query: 304 AEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQ 363
             VVNF +WF F+FP  +I+L+++W W+  LFLG NF++   + +K + +++Q +   IQ
Sbjct: 258 GNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQ-EQQQAAYCVIQ 316

Query: 364 EEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDS--FFEKKGYR--TDATVSVF 419
            E+  LG +++ E      F+++ +LWFTREPGF  GW +  F   KG    +D TV++F
Sbjct: 317 TEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIF 376

Query: 420 LGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASG 479
           +G ++F+IP+K P  G   D EN         ++ WK   + MPW IV+L+GGGYALA G
Sbjct: 377 IGIIMFIIPSKFP--GLTQDPENPGKLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKG 434

Query: 480 SKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETL 539
           S+ SGLS W+GN++  L S+P  A+ ++  +LV+  TE  SN AT TIFLPIL S+++ +
Sbjct: 435 SERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAI 494

Query: 540 HINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVA 599
            ++PLY ++P T+  S A MLPV  PPNAIVFS+G  ++ DM +AG  +N+IG++I+ +A
Sbjct: 495 CLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALA 554

Query: 600 INTWGVSLFHLDTYPAWARVSNITDQ 625
           IN+WG+ LF L ++P+WA+ SN T Q
Sbjct: 555 INSWGIPLFSLHSFPSWAQ-SNTTAQ 579


>gi|225637549 solute carrier family 13, member 2 isoform a [Homo
           sapiens]
          Length = 641

 Score =  454 bits (1168), Expect = e-127
 Identities = 257/675 (38%), Positives = 382/675 (56%), Gaps = 106/675 (15%)

Query: 5   QGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAF 64
           Q L   R  L+V  VP+LLLPLP+L PS EA CAY +I+ A++W +EA+PL   AL P  
Sbjct: 6   QALWAYRSYLIVFFVPILLLPLPILVPSKEAYCAYAIILMALFWCTEALPLAVTALFPLI 65

Query: 65  LYPFFGVLRSNE------------------------------------------------ 76
           L+P  G++ ++E                                                
Sbjct: 66  LFPMMGIVDASEIIQRPFPSSFESPGECQSVGMSVTASHNLGGTVGDSRVFPPLSHVSTC 125

Query: 77  -VAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCCTTLLS 135
            VA EY K++ LL  G + VA AVE WNLHKRIALR++L+ G +P  L+L FM  T  LS
Sbjct: 126 QVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLILGFMLVTAFLS 185

Query: 136 MWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFV 195
           MW+SNT+T+AM++PI  AVL +L S++       +SN EE         ++ P+ EL   
Sbjct: 186 MWISNTATSAMMVPIAHAVLDQLHSSQ------ASSNVEEG--------SNNPTFEL--- 228

Query: 196 NEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRK 255
            E S     T + N                           Q  P     S  +  L++K
Sbjct: 229 QEPSPQKEVTKLDN--------------------------GQALPVTSASSEGRAHLSQK 262

Query: 256 YRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPA-AEVVNFGTWFL 314
           +       + +C+SL + YSA+IGG+ T+ GT+ +L+     N+ +P    VVNF +WF 
Sbjct: 263 HLH-----LTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQNGNVVNFASWFS 317

Query: 315 FSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISY 374
           F+FP  +I+L+++W W+  LFLG NF++   + +K + +++Q +   IQ E+  LG +++
Sbjct: 318 FAFPTMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQ-EQQQAAYCVIQTEHRLLGPMTF 376

Query: 375 PEMVTGFFFILMTVLWFTREPGFVPGWDS--FFEKKGYR--TDATVSVFLGFLLFLIPAK 430
            E      F+++ +LWFTREPGF  GW +  F   KG    +D TV++F+G ++F+IP+K
Sbjct: 377 AEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIFIGIIMFIIPSK 436

Query: 431 KPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIG 490
            P  G   D EN         ++ WK   + MPW IV+L+GGGYALA GS+ SGLS W+G
Sbjct: 437 FP--GLTQDPENPGKLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKGSERSGLSEWLG 494

Query: 491 NQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPV 550
           N++  L S+P  A+ ++  +LV+  TE  SN AT TIFLPIL S+++ + ++PLY ++P 
Sbjct: 495 NKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAICLHPLYVMLPC 554

Query: 551 TMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSLFHL 610
           T+  S A MLPV  PPNAIVFS+G  ++ DM +AG  +N+IG++I+ +AIN+WG+ LF L
Sbjct: 555 TLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALAINSWGIPLFSL 614

Query: 611 DTYPAWARVSNITDQ 625
            ++P+WA+ SN T Q
Sbjct: 615 HSFPSWAQ-SNTTAQ 628


>gi|31377715 solute carrier family 13 member 3 isoform a [Homo
           sapiens]
          Length = 602

 Score =  451 bits (1161), Expect = e-127
 Identities = 238/615 (38%), Positives = 368/615 (59%), Gaps = 47/615 (7%)

Query: 11  RKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPFFG 70
           R+LL+++  PL LLP+    P  E  C +V+++ AVYW +EA+PL   AL+P  L+PF G
Sbjct: 15  RRLLVLLFTPLALLPVVFALPPKEGRCLFVILLMAVYWCTEALPLSVTALLPIVLFPFMG 74

Query: 71  VLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFMCC 130
           +L SN+V  +YF +T  L +  + +A+A+E+WNLH+RIAL+++++ G +P  L+L  M  
Sbjct: 75  ILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNLHRRIALKILMLVGVQPARLILGMMVT 134

Query: 131 TTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSL 190
           T+ LSMWLSNT++TAM++PI  A+L+ L   ++ +                      PS 
Sbjct: 135 TSFLSMWLSNTASTAMMLPIANAILKSLFGQKEVR--------------------KDPSQ 174

Query: 191 ELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQ-EKPQVLTPSPRK 249
           E    +EE+    T  +    L+ VP+    + +       K HP + E P  L    RK
Sbjct: 175 E----SEEN----TAAVRRNGLHTVPTEMQFLASTEA----KDHPGETEVPLDLPADSRK 222

Query: 250 QKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPAAEVVNF 309
           +    +YR +    I K   +SI YSA+IGG  T+ GT+ +LI L    + +P  +VVNF
Sbjct: 223 ED---EYRRN----IWKGFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFPQCDVVNF 275

Query: 310 GTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQEEYEKL 369
           G+WF+F+FP+ L+ L+  W W+ +L+ G +F+       + +T  E  +   I+EEY+ L
Sbjct: 276 GSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGWRKNKSEIRTNAEDRARAVIREEYQNL 335

Query: 370 GDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKGYRTDATVSVFLGFLLFLIPA 429
           G I + E      F +  +L FTR+P F+PGW S F   G+ +DA   V +  +LF  P+
Sbjct: 336 GPIKFAEQAVFILFCMFAILLFTRDPKFIPGWASLFNP-GFLSDAVTGVAIVTILFFFPS 394

Query: 430 KKPCFGKKND--GENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASGSKSSGLST 487
           ++P      D    N E    TEP++TWK  Q+T+PW I++L+GGG+A+A G + SGLS 
Sbjct: 395 QRPSLKWWFDFKAPNTE----TEPLLTWKKAQETVPWNIILLLGGGFAMAKGCEESGLSV 450

Query: 488 WIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLHINPLYTL 547
           WIG Q+  L ++PP    LL  ++++  TEF SN ATI IFLP+L  L+  L ++PLY +
Sbjct: 451 WIGGQLHPLENVPPALAVLLITVVIAFFTEFASNTATIIIFLPVLAELAIRLRVHPLYLM 510

Query: 548 IPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAINTWGVSL 607
           IP T+  SFA MLPV  PPN+I F+ GH  +KDMV+ GL +N++G++++ +A+NTW  ++
Sbjct: 511 IPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDMVRTGLLMNLMGVLLLSLAMNTWAQTI 570

Query: 608 FHLDTYPAWARVSNI 622
           F L T+P WA + ++
Sbjct: 571 FQLGTFPDWADMYSV 585


>gi|58761541 solute carrier family 13 member 3 isoform b [Homo
           sapiens]
          Length = 555

 Score =  427 bits (1097), Expect = e-119
 Identities = 226/581 (38%), Positives = 347/581 (59%), Gaps = 47/581 (8%)

Query: 45  AVYWVSEAVPLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNL 104
           AVYW +EA+PL   AL+P  L+PF G+L SN+V  +YF +T  L +  + +A+A+E+WNL
Sbjct: 2   AVYWCTEALPLSVTALLPIVLFPFMGILPSNKVCPQYFLDTNFLFLSGLIMASAIEEWNL 61

Query: 105 HKRIALRMVLMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDE 164
           H+RIAL+++++ G +P  L+L  M  T+ LSMWLSNT++TAM++PI  A+L+ L   ++ 
Sbjct: 62  HRRIALKILMLVGVQPARLILGMMVTTSFLSMWLSNTASTAMMLPIANAILKSLFGQKEV 121

Query: 165 QLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKT 224
           +                      PS E    +EE+    T  +    L+ VP+    + +
Sbjct: 122 R--------------------KDPSQE----SEEN----TAAVRRNGLHTVPTEMQFLAS 153

Query: 225 ANQHQGKKQHPSQ-EKPQVLTPSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTT 283
                  K HP + E P  L    RK+    +YR +    I K   +SI YSA+IGG  T
Sbjct: 154 TEA----KDHPGETEVPLDLPADSRKED---EYRRN----IWKGFLISIPYSASIGGTAT 202

Query: 284 IIGTSTSLIFLEHFNNQYPAAEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKET 343
           + GT+ +LI L    + +P  +VVNFG+WF+F+FP+ L+ L+  W W+ +L+ G +F+  
Sbjct: 203 LTGTAPNLILLGQLKSFFPQCDVVNFGSWFIFAFPLMLLFLLAGWLWISFLYGGLSFRGW 262

Query: 344 CSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDS 403
                + +T  E  +   I+EEY+ LG I + E      F +  +L FTR+P F+PGW S
Sbjct: 263 RKNKSEIRTNAEDRARAVIREEYQNLGPIKFAEQAVFILFCMFAILLFTRDPKFIPGWAS 322

Query: 404 FFEKKGYRTDATVSVFLGFLLFLIPAKKPCFGKKND--GENQEHSLGTEPIITWKDFQKT 461
            F   G+ +DA   V +  +LF  P+++P      D    N E    TEP++TWK  Q+T
Sbjct: 323 LFNP-GFLSDAVTGVAIVTILFFFPSQRPSLKWWFDFKAPNTE----TEPLLTWKKAQET 377

Query: 462 MPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSN 521
           +PW I++L+GGG+A+A G + SGLS WIG Q+  L ++PP    LL  ++++  TEF SN
Sbjct: 378 VPWNIILLLGGGFAMAKGCEESGLSVWIGGQLHPLENVPPALAVLLITVVIAFFTEFASN 437

Query: 522 PATITIFLPILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDM 581
            ATI IFLP+L  L+  L ++PLY +IP T+  SFA MLPV  PPN+I F+ GH  +KDM
Sbjct: 438 TATIIIFLPVLAELAIRLRVHPLYLMIPGTVGCSFAFMLPVSTPPNSIAFASGHLLVKDM 497

Query: 582 VKAGLGVNVIGLVIVMVAINTWGVSLFHLDTYPAWARVSNI 622
           V+ GL +N++G++++ +A+NTW  ++F L T+P WA + ++
Sbjct: 498 VRTGLLMNLMGVLLLSLAMNTWAQTIFQLGTFPDWADMYSV 538


>gi|225637552 solute carrier family 13, member 2 isoform c [Homo
           sapiens]
          Length = 549

 Score =  412 bits (1060), Expect = e-115
 Identities = 238/626 (38%), Positives = 353/626 (56%), Gaps = 100/626 (15%)

Query: 5   QGLLRVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAF 64
           Q L   R  L+V  VP+LLLPLP+L PS                                
Sbjct: 6   QALWAYRSYLIVFFVPILLLPLPILVPS-------------------------------- 33

Query: 65  LYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLL 124
                      +VA EY K++ LL  G + VA AVE WNLHKRIALR++L+ G +P  L+
Sbjct: 34  -----------KVAVEYLKDSNLLFFGGLLVAIAVEHWNLHKRIALRVLLIVGVRPAPLI 82

Query: 125 LCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVK 184
           L FM  T  LSMW+SNT+T+AM++PI  AVL +L S++       +SN EE         
Sbjct: 83  LGFMLVTAFLSMWISNTATSAMMVPIAHAVLDQLHSSQ------ASSNVEEG-------- 128

Query: 185 NSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLT 244
           ++ P+ EL    E S     T + N                           Q  P    
Sbjct: 129 SNNPTFEL---QEPSPQKEVTKLDN--------------------------GQALPVTSA 159

Query: 245 PSPRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYPA- 303
            S  +  L++K+       + +C+SL + YSA+IGG+ T+ GT+ +L+     N+ +P  
Sbjct: 160 SSEGRAHLSQKHLH-----LTQCMSLCVCYSASIGGIATLTGTAPNLVLQGQINSLFPQN 214

Query: 304 AEVVNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKETCSLSKKKKTKREQLSEKRIQ 363
             VVNF +WF F+FP  +I+L+++W W+  LFLG NF++   + +K + +++Q +   IQ
Sbjct: 215 GNVVNFASWFSFAFPTMVILLLLAWLWLQILFLGFNFRKNFGIGEKMQ-EQQQAAYCVIQ 273

Query: 364 EEYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDS--FFEKKGYR--TDATVSVF 419
            E+  LG +++ E      F+++ +LWFTREPGF  GW +  F   KG    +D TV++F
Sbjct: 274 TEHRLLGPMTFAEKAISILFVILVLLWFTREPGFFLGWGNLAFPNAKGESMVSDGTVAIF 333

Query: 420 LGFLLFLIPAKKPCFGKKNDGENQEHSLGTEPIITWKDFQKTMPWEIVILVGGGYALASG 479
           +G ++F+IP+K P  G   D EN         ++ WK   + MPW IV+L+GGGYALA G
Sbjct: 334 IGIIMFIIPSKFP--GLTQDPENPGKLKAPLGLLDWKTVNQKMPWNIVLLLGGGYALAKG 391

Query: 480 SKSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETL 539
           S+ SGLS W+GN++  L S+P  A+ ++  +LV+  TE  SN AT TIFLPIL S+++ +
Sbjct: 392 SERSGLSEWLGNKLTPLQSVPAPAIAIILSLLVATFTECTSNVATTTIFLPILASMAQAI 451

Query: 540 HINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVA 599
            ++PLY ++P T+  S A MLPV  PPNAIVFS+G  ++ DM +AG  +N+IG++I+ +A
Sbjct: 452 CLHPLYVMLPCTLATSLAFMLPVATPPNAIVFSFGDLKVLDMARAGFLLNIIGVLIIALA 511

Query: 600 INTWGVSLFHLDTYPAWARVSNITDQ 625
           IN+WG+ LF L ++P+WA+ SN T Q
Sbjct: 512 INSWGIPLFSLHSFPSWAQ-SNTTAQ 536


>gi|219802232 solute carrier family 13, member 5 isoform b [Homo
           sapiens]
          Length = 522

 Score =  405 bits (1040), Expect = e-113
 Identities = 231/622 (37%), Positives = 349/622 (56%), Gaps = 119/622 (19%)

Query: 9   RVRKLLLVVCVPLLLLPLPVLHPSSEASCAYVLIVTAVYWVSEAVPLGAAALVPAFLYPF 68
           + +  +++   PLLLLPL +L P+    CAYV+I+ A+YW +E +PL   +L+P  L+P 
Sbjct: 10  KFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPL 69

Query: 69  FGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGMLLLCFM 128
           F +L S +V  +Y K+T +L +G + VA AVE+WNLHKRIALR +L  GAKP  L+L FM
Sbjct: 70  FQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFM 129

Query: 129 CCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQP 188
             T LLSMW+SNT+TTAM++PIVEA+LQ        Q+ A ++ TE              
Sbjct: 130 GVTALLSMWISNTATTAMMVPIVEAILQ--------QMEATSAATEAG------------ 169

Query: 189 SLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGK-KQHPSQEKPQVLTPSP 247
            LEL+                                   +GK K+ P     QV+   P
Sbjct: 170 -LELV----------------------------------DKGKAKELPGS---QVIFEGP 191

Query: 248 RKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSLIFLEHFNNQYP-AAEV 306
              +   + R      +CK ++L I Y+A+IGG  T+ GT  +++ L   N  +P + ++
Sbjct: 192 TLGQQEDQERKR----LCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDL 247

Query: 307 VNFGTWFLFSFPISLIMLVVSWFWMHWLFLGCNFKET--CSLSKKKKTKREQLSEKRIQE 364
           VNF +WF F+FP  L+ML+ +W W+ ++++  NFK++  C L  KK    E+ + K +QE
Sbjct: 248 VNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKKN---EKAALKVLQE 304

Query: 365 EYEKLGDISYPEMVTGFFFILMTVLWFTREPGFVPGWDSFFEKKG---YRTDATVSVFLG 421
           EY KLG +S+ E+     F L+ +LWF+R+PGF+PGW +    +G   Y +DATV++F+ 
Sbjct: 305 EYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVA 364

Query: 422 FLLFLIPAKKPCFGKKNDGENQEHS-LGTEPIITWKDFQKTMPWEIVILVGGGYALASGS 480
            LLF++P++KP F  ++  E +  +     P++ WK  Q+ +PW IV+L+GGG+ALA GS
Sbjct: 365 TLLFIVPSQKPKFNFRSQTEEERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGS 424

Query: 481 KSSGLSTWIGNQMLSLSSLPPWAVTLLACILVSIVTEFVSNPATITIFLPILCSLSETLH 540
           ++SGLS W+G QM  L ++PP A+TL+  +LV++ TE  SN AT T+FLPI  S      
Sbjct: 425 EASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFAS------ 478

Query: 541 INPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIGLVIVMVAI 600
                                                   MVK G+ +N+IG+  V +A+
Sbjct: 479 ----------------------------------------MVKTGVIMNIIGVFCVFLAV 498

Query: 601 NTWGVSLFHLDTYPAWARVSNI 622
           NTWG ++F LD +P WA V++I
Sbjct: 499 NTWGRAIFDLDHFPDWANVTHI 520


>gi|157266326 oculocutaneous albinism II [Homo sapiens]
          Length = 838

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 35/149 (23%), Positives = 72/149 (48%), Gaps = 8/149 (5%)

Query: 452 IITWKDFQKTMPWEIVILVGGGYALASGSKSSGLSTWIGNQMLSLSSLPPWAVTLLACIL 511
           ++ W DF      E + L+ G   L +    +G   +   +   LS    WA+ ++ C++
Sbjct: 379 VVEWIDF------ETLALLFGMMILVAIFSETGFFDYCAVKAYRLSRGRVWAMIIMLCLI 432

Query: 512 VSIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISF-AVMLPVGNPPNAIV 570
            ++++ F+ N  T+ +F P+   L E L+++P   LI   +  +       +G+PPN I+
Sbjct: 433 AAVLSAFLDNVTTMLLFTPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAIGDPPNVII 492

Query: 571 FSYGHCQIKDMVKAGLGVNV-IGLVIVMV 598
            S    +   +  AG   ++ IG+ +V++
Sbjct: 493 VSNQELRKMGLDFAGFTAHMFIGICLVLL 521


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 35.4 bits (80), Expect = 0.16
 Identities = 41/181 (22%), Positives = 68/181 (37%), Gaps = 28/181 (15%)

Query: 138 LSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEE------------------AEPI 179
           +SN    ++V    +    +L+    + L AGN NT E                  A P 
Sbjct: 381 VSNVKPLSLVNQAKKETYMKLIVPSPDVLKAGNKNTSEESSLLTSELRSKREQYKQAFPS 440

Query: 180 SLDVKNSQPSLELIFV-------NEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKK 232
            L  + S  SL+ +            S A     + N + N  P +TN +   +Q  G  
Sbjct: 441 QLKKQESSKSLKKVIAALSNPKATSSSPAHPKQTLENNHPN--PFLTNALLGNHQPNGVI 498

Query: 233 QHPSQEKPQVLTPSPRKQ-KLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIGTSTSL 291
           Q   QE P  LT   + Q K+N    +         ++LS S   T G  T ++ +++ +
Sbjct: 499 QSVIQEAPLALTTKTKMQSKINENIAAASSTPFSSPVNLSTSGRRTPGNQTPVMPSASPI 558

Query: 292 I 292
           +
Sbjct: 559 L 559


>gi|13677214 receptor-type protein tyrosine phosphatase O isoform a
           precursor [Homo sapiens]
          Length = 1216

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 35/162 (21%), Positives = 61/162 (37%), Gaps = 36/162 (22%)

Query: 54  PLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMV 113
           PLG  A+V ++  P+ GV R   V   YF   T+             +W  +  IA  + 
Sbjct: 540 PLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATM-----------TSEWTTYYEIAATVS 588

Query: 114 LMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNT 173
           L A  +             LL  W  N   T             +V+  D +L   +S+T
Sbjct: 589 LTASVR----------IANLLPAWYYNFRVT-------------MVTWGDPELSCCDSST 625

Query: 174 EE--AEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLN 213
                 P++ ++ + +    L++++     D T L H+  L+
Sbjct: 626 ISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLH 667


>gi|4506323 receptor-type protein tyrosine phosphatase O isoform b
           precursor [Homo sapiens]
          Length = 1188

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 35/162 (21%), Positives = 61/162 (37%), Gaps = 36/162 (22%)

Query: 54  PLGAAALVPAFLYPFFGVLRSNEVAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMV 113
           PLG  A+V ++  P+ GV R   V   YF   T+             +W  +  IA  + 
Sbjct: 540 PLGPTAVVLSWTRPYLGVFRKYVVEMFYFNPATM-----------TSEWTTYYEIAATVS 588

Query: 114 LMAGAKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNT 173
           L A  +             LL  W  N   T             +V+  D +L   +S+T
Sbjct: 589 LTASVR----------IANLLPAWYYNFRVT-------------MVTWGDPELSCCDSST 625

Query: 174 EE--AEPISLDVKNSQPSLELIFVNEESNADLTTLMHNENLN 213
                 P++ ++ + +    L++++     D T L H+  L+
Sbjct: 626 ISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLH 667


>gi|25282469 retinol dehydrogenase 10 [Homo sapiens]
          Length = 341

 Score = 33.1 bits (74), Expect = 0.79
 Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 3/110 (2%)

Query: 77  VAAEYFKNTTLLLVGVICVAAAVEKWNLHKRIALRMVLMAGAKPGM---LLLCFMCCTTL 133
           +  E+F  T  +L   +  AA        K +A ++ L+ GA  G+     L F     L
Sbjct: 3   IVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRAL 62

Query: 134 LSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDV 183
           L +W  NT +      +V  + ++L +A+   L AGN   E     +L V
Sbjct: 63  LVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQV 112


>gi|40217829 G protein-coupled receptor 68 [Homo sapiens]
          Length = 375

 Score = 32.7 bits (73), Expect = 1.0
 Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 19/84 (22%)

Query: 533 CSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIVFSYGHCQIKDMVKAGLGVNVIG 592
           C++  T+H     TL PV     +  +L VG P N +   +G+ QIK   +  LGV +  
Sbjct: 23  CTIDHTIH----QTLAPVV----YVTVLVVGFPANCLSLYFGYLQIK--ARNELGVYLCN 72

Query: 593 LVIVMVAINTWGVSLFHLDTYPAW 616
           L +           LF++ + P W
Sbjct: 73  LTV---------ADLFYICSLPFW 87


>gi|194018482 NLR family, pyrin domain containing 4 [Homo sapiens]
          Length = 994

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 35/138 (25%), Positives = 61/138 (44%), Gaps = 19/138 (13%)

Query: 332 HWLFLGCNFKETCSLSKKKKTKRE-----QLSE---KRIQEEYEKLGDISYPEMVTGFFF 383
           HW+FLGC    T  L+KK++ K +     QLS+   ++I +  + LG+   P+       
Sbjct: 495 HWIFLGCFL--TGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLA 552

Query: 384 ILMTVLWFTREPGFVPGWDSFFEKKGY----RTDATVSVFLGFLLFLIPAKKPCFGKKN- 438
           I    L+  ++P FV    +  ++  +      D  VS +   L +    +K CF  +N 
Sbjct: 553 IFY-CLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYC--LKYCSSLRKLCFSVQNV 609

Query: 439 -DGENQEHSLGTEPIITW 455
              E++  S     +I W
Sbjct: 610 FKKEDEHSSTSDYSLICW 627


>gi|54606888 hypothetical protein LOC23251 [Homo sapiens]
          Length = 916

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 37/136 (27%), Positives = 55/136 (40%), Gaps = 7/136 (5%)

Query: 174 EEAEPISLDVKNSQPSLELIFVNEESNADLTTLMHN-ENLNGV-PSITNPI-KTANQHQG 230
           +++ PI+  +K +  S E  FV +           +  NL  V PS+  PI K  N+H+ 
Sbjct: 228 QDSLPINQSIKETFISNEEPFVVQSCVQKRNIFKEDFHNLMAVSPSLVGPISKAENEHRE 287

Query: 231 KKQHPSQEKPQVLTPS----PRKQKLNRKYRSHHDQMICKCLSLSISYSATIGGLTTIIG 286
            +      KP     S       Q LN  Y    D+   K  SL    ++T  G T ++G
Sbjct: 288 PQSRKEPHKPPFFNHSFEMPYNSQYLNPVYSPVPDKRRAKHESLDDLQASTYFGPTPVMG 347

Query: 287 TSTSLIFLEHFNNQYP 302
           T  +   L   N Q P
Sbjct: 348 TQEARRCLGKPNKQTP 363


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

Query: 184  KNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVL 243
            KN  P   +   +E+ +  L ++    +    P + NP K++  H      P Q     L
Sbjct: 1413 KNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHT-----PVQHG--YL 1465

Query: 244  TPSPRKQKLNRKYRSHHDQ 262
            +P P  Q+L   YR HH Q
Sbjct: 1466 SPKPPSQQLGSPYRPHHSQ 1484


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

Query: 184  KNSQPSLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVL 243
            KN  P   +   +E+ +  L ++    +    P + NP K++  H      P Q     L
Sbjct: 1413 KNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHT-----PVQHG--YL 1465

Query: 244  TPSPRKQKLNRKYRSHHDQ 262
            +P P  Q+L   YR HH Q
Sbjct: 1466 SPKPPSQQLGSPYRPHHSQ 1484


>gi|56676335 RAP1 interacting factor 1 [Homo sapiens]
          Length = 2472

 Score = 31.6 bits (70), Expect = 2.3
 Identities = 26/95 (27%), Positives = 43/95 (45%), Gaps = 9/95 (9%)

Query: 160  SAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELI---FVNEESNADLT----TLMHNENL 212
            + E+  L+  N+  E+   I+L+ K + P + +     VNE+S   +T    TL  +   
Sbjct: 1361 TVENAVLLETNTVEEKNVEINLESKENTPPVVISADQMVNEDSQVQITPNQKTLRRSSRR 1420

Query: 213  NG--VPSITNPIKTANQHQGKKQHPSQEKPQVLTP 245
                V S T      N HQ K++   +EKP   +P
Sbjct: 1421 RSEVVESTTESQDKENSHQKKERRKEEEKPLQKSP 1455


>gi|188497642 ARHGAP15 [Homo sapiens]
          Length = 475

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 19/72 (26%), Positives = 33/72 (45%), Gaps = 3/72 (4%)

Query: 195 VNEESNADLTTLMHNENLNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNR 254
           + + +N+D +    N    G  ++   IK AN H  +    SQ K  +LT   +  +   
Sbjct: 1   MQKSTNSDTSVETLNSTRQGTGAVQMRIKNANSHHDRL---SQSKSMILTDVGKVTEPIS 57

Query: 255 KYRSHHDQMICK 266
           ++R +H Q I K
Sbjct: 58  RHRRNHSQHILK 69


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 31.2 bits (69), Expect = 3.0
 Identities = 21/107 (19%), Positives = 49/107 (45%), Gaps = 1/107 (0%)

Query: 153 AVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNEESNADLTT-LMHNEN 211
           ++L +++S+EDE+   G+ +T++ E     ++  +   +     E+    + T + H E 
Sbjct: 108 SLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEK 167

Query: 212 LNGVPSITNPIKTANQHQGKKQHPSQEKPQVLTPSPRKQKLNRKYRS 258
             G   +    K   +   K++   +EKP+  T +  ++K     +S
Sbjct: 168 EKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKS 214


>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
           sapiens]
          Length = 1366

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 339 NFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTG 380
           +F E+  ++  K TK  ++++ ++ EE EK   IS PE   G
Sbjct: 392 HFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNG 433


>gi|47717106 zinc finger, FYVE domain containing 9 isoform 3 [Homo
           sapiens]
          Length = 1425

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 339 NFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTG 380
           +F E+  ++  K TK  ++++ ++ EE EK   IS PE   G
Sbjct: 392 HFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNG 433


>gi|6552337 zinc finger, FYVE domain containing 9 isoform 2 [Homo
           sapiens]
          Length = 762

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 14/42 (33%), Positives = 24/42 (57%)

Query: 339 NFKETCSLSKKKKTKREQLSEKRIQEEYEKLGDISYPEMVTG 380
           +F E+  ++  K TK  ++++ ++ EE EK   IS PE   G
Sbjct: 392 HFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNG 433


>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
          Length = 1219

 Score = 30.8 bits (68), Expect = 3.9
 Identities = 28/106 (26%), Positives = 46/106 (43%), Gaps = 19/106 (17%)

Query: 138 LSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQPSLELIFVNE 197
           +S T  T+M+M  ++ ++QE    + E L   N   E+ + IS          ELI  N+
Sbjct: 554 MSVTMETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKIS----------ELIERNQ 603

Query: 198 ESNADLTTLMHNENLNGVPSITNPIKTANQH-QGKKQHPSQEKPQV 242
                   +M   N        N ++TA ++ Q +  H  QEK +V
Sbjct: 604 RYVEQSNLMMEKRN--------NSLQTATENTQARVLHAEQEKAKV 641


>gi|5174593 melatonin receptor 1A [Homo sapiens]
          Length = 350

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 27/114 (23%), Positives = 51/114 (44%), Gaps = 20/114 (17%)

Query: 500 PPWAVTLLACILV-SIVTEFVSNPATITIFLPILCSLSETLHINPLYTLIPVTMCISFAV 558
           P W  + LAC+L+ +IV + + N       L ++ S+     +     +  V++ ++  V
Sbjct: 23  PSWLASALACVLIFTIVVDILGN-------LLVILSVYRNKKLRNAGNIFVVSLAVADLV 75

Query: 559 MLPVGNP-------PNAIVFSYGHCQIKDMVKAGLGVNVIGLV--IVMVAINTW 603
           +     P        N     Y HCQ+   +   +G++VIG +  I  +AIN +
Sbjct: 76  VAIYPYPLVLMSIFNNGWNLGYLHCQVSGFL---MGLSVIGSIFNITGIAINRY 126


>gi|24475869 cellular repressor of E1A-stimulated genes 2 [Homo
           sapiens]
          Length = 290

 Score = 30.4 bits (67), Expect = 5.1
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 10/69 (14%)

Query: 118 AKPGMLLLCFMCCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAE 177
           A+PG  L   +CC+ LLS         A    IV +V   + +  DE+L   +++TEEA 
Sbjct: 10  ARPGTRLSWLLCCSALLS--------PAAGYVIVSSVSWAVTNEVDEEL--DSASTEEAM 59

Query: 178 PISLDVKNS 186
           P  L+   S
Sbjct: 60  PALLEDSGS 68


>gi|218083730 zinc finger protein 237 isoform 3 [Homo sapiens]
          Length = 669

 Score = 30.0 bits (66), Expect = 6.7
 Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 5/120 (4%)

Query: 129 CCTTLLSMWLSNTSTTAMVMPIVEAVLQELVSAEDEQLVAGNSNTEEAEPISLDVKNSQP 188
           CC + ++ +     T +  +   E   +     E+E+ + G+SNT   +   +  K  + 
Sbjct: 407 CCQSCINEYKQMMETKSKKLTASENRKRNAFREENEKQLYGSSNTLLKKIEGIPEKKEKT 466

Query: 189 SLELIFVNEESNADLTTLMHNENLNGVPSITNPIKTANQHQ-GKKQHPSQEKPQVLTPSP 247
           S   + V  E   D  TL+  EN+N  PS T+ I    Q Q  +K       P VL+  P
Sbjct: 467 SQLQLSV--ECGTD--TLLIQENVNLPPSSTSTIADTFQEQLEEKNFEDSIVPVVLSADP 522


>gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor
           [Homo sapiens]
          Length = 818

 Score = 29.6 bits (65), Expect = 8.7
 Identities = 15/41 (36%), Positives = 21/41 (51%)

Query: 530 PILCSLSETLHINPLYTLIPVTMCISFAVMLPVGNPPNAIV 570
           P+  S+S  LHI  +    PV    S+ V +P  NPP A +
Sbjct: 427 PLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASI 467


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,135,744
Number of Sequences: 37866
Number of extensions: 1017656
Number of successful extensions: 3250
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 3169
Number of HSP's gapped (non-prelim): 56
length of query: 626
length of database: 18,247,518
effective HSP length: 108
effective length of query: 518
effective length of database: 14,157,990
effective search space: 7333838820
effective search space used: 7333838820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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