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Search of human proteins with 31711992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]
(647 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens] 1296 0.0
gi|203098816 pyruvate dehydrogenase complex, component X isoform... 318 7e-87
gi|203098753 pyruvate dehydrogenase complex, component X isoform... 315 8e-86
gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component... 158 2e-38
gi|110671329 dihydrolipoamide branched chain transacylase precur... 154 3e-37
gi|157168329 formin 1 [Homo sapiens] 49 1e-05
gi|149363685 hypothetical protein LOC23379 [Homo sapiens] 49 2e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 49 2e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 49 2e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 49 2e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 49 2e-05
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 49 2e-05
gi|9945318 MAX binding protein [Homo sapiens] 48 3e-05
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 47 4e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 47 5e-05
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 47 5e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 47 5e-05
gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2) int... 47 7e-05
gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 46 9e-05
gi|148613878 acrosin precursor [Homo sapiens] 45 2e-04
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 45 2e-04
gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens] 45 2e-04
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 45 2e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 45 2e-04
gi|153792074 proline rich 12 [Homo sapiens] 45 2e-04
gi|169163027 PREDICTED: similar to Putative acrosin-like proteas... 45 3e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 4e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 4e-04
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 44 4e-04
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 44 4e-04
>gi|31711992 dihydrolipoamide S-acetyltransferase [Homo sapiens]
Length = 647
Score = 1296 bits (3354), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCG 60
MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCG
Sbjct: 1 MWRVCARRAQNVAPWAGLEARWTALQEVPGTPRVTSRSGPAPARRNSVTTGYGGVRALCG 60
Query: 61 WTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKIN 120
WTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKIN
Sbjct: 61 WTPSSGATPRNRLLLQLLGSPGRRYYSLPPHQKVPLPSLSPTMQAGTIARWEKKEGDKIN 120
Query: 121 EGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYT 180
EGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYT
Sbjct: 121 EGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIGAIICITVGKPEDIEAFKNYT 180
Query: 181 LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEK 240
LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEK
Sbjct: 181 LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEK 240
Query: 241 KVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADI 300
KVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADI
Sbjct: 241 KVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADI 300
Query: 301 SAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPL 360
SAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPL
Sbjct: 301 SAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPL 360
Query: 361 AKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF 420
AKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF
Sbjct: 361 AKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF 420
Query: 421 TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFI 480
TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFI
Sbjct: 421 TDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFI 480
Query: 481 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 540
IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND
Sbjct: 481 IKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIAND 540
Query: 541 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 600
VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA
Sbjct: 541 VVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPA 600
Query: 601 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 647
DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL
Sbjct: 601 DNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 647
>gi|203098816 pyruvate dehydrogenase complex, component X isoform 2
[Homo sapiens]
Length = 486
Score = 318 bits (816), Expect = 7e-87
Identities = 195/483 (40%), Positives = 278/483 (57%), Gaps = 50/483 (10%)
Query: 197 PAATASPPTP-SAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEI 255
P + +PP S+ AP +++L+P+LSPTM G + +W KK GE +S GD L EI
Sbjct: 19 PGSGKAPPAEISSGAPDFPGGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEI 78
Query: 256 ETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVT-DL 314
ETDKA + + ++G LAKI+V EG++++ LG+ + +IVE+ D ++ E+ D+
Sbjct: 79 ETDKAVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGED------WKHVEIPKDV 132
Query: 315 KPQVPPPTPPPVAAVP-PTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLT 373
P PPP P P P PQ P P T R +SP A+ + + +D +
Sbjct: 133 GP--PPPVSKPSEPRPSPEPQISIPVKKEHIPGTL-----RFRLSPAARNILEKHSLDAS 185
Query: 374 QVKGTGPDGRITKKDIDSFVP---------SKVAPAPAA-------------------VV 405
Q TGP G TK+D V S+ PAP A V+
Sbjct: 186 QGTATGPRGIFTKEDALKLVQLKQTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVI 245
Query: 406 PPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELN 465
PP P G FT+IP SNIRRVIA+RL +SK T+PH Y + D ++G VL VR++L
Sbjct: 246 PPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLV 305
Query: 466 KILEGRSKISVNDFIIKASALACLKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPI 525
K K+SVNDFIIKA+A+ ++P+ N SW +Q +D+SVAV+T GL+TPI
Sbjct: 306 K---DDIKVSVNDFIIKAAAVTLKQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPI 362
Query: 526 VFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQA 585
+ +A KG++ IA+ V +L+ KAR+GKL P E+QGG+F+ISNLGMFGI F+A+INPPQA
Sbjct: 363 IKDAAAKGIQEIADSVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQA 422
Query: 586 CILAIGASEDKLVPADNEKG---FDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKP 642
CILA+G L ++E+G +++VT+S D RVVD + ++L F+ LE P
Sbjct: 423 CILAVGRFRPVLKLTEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 482
Query: 643 ITM 645
I +
Sbjct: 483 IRL 485
Score = 92.8 bits (229), Expect = 9e-19
Identities = 83/300 (27%), Positives = 126/300 (42%), Gaps = 60/300 (20%)
Query: 93 KVPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAE 152
K+ +PSLSPTM+ G I +W KKEG+ ++ GD + E+ETDKA V ++ ++ +AKI+V E
Sbjct: 43 KILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEE 102
Query: 153 GTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAA----PAPTPAATASPPTPSA 208
G++++ +G++I + V + ED +K+ + P P + P P+P S P
Sbjct: 103 GSKNIRLGSLIGLIVEEGED---WKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKE 159
Query: 209 QAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQE 268
PG+ L LSP + + EK S
Sbjct: 160 HIPGT--------LRFRLSPA---------ARNILEKHS--------------------- 181
Query: 269 EGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAA 328
+ +GT P G I KE + + ++T+ +P P PT P A
Sbjct: 182 ------LDASQGTATGPRG-----IFTKEDALKLVQLKQTGKITESRP-TPAPTATPTAP 229
Query: 329 VP--PTPQPLAPTPSAPCPATPAGPKG-RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRIT 385
P T P P P P +TP P F A + LT+ K T P T
Sbjct: 230 SPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYAT 289
>gi|203098753 pyruvate dehydrogenase complex, component X isoform 1
[Homo sapiens]
Length = 501
Score = 315 bits (807), Expect = 8e-86
Identities = 189/460 (41%), Positives = 269/460 (58%), Gaps = 49/460 (10%)
Query: 219 MQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVP 278
+++L+P+LSPTM G + +W KK GE +S GD L EIETDKA + + ++G LAKI+V
Sbjct: 57 IKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVE 116
Query: 279 EGTRDVPLGTPLCIIVEKEADISAFADYRPTEVT-DLKPQVPPPTPPPVAAVP-PTPQPL 336
EG++++ LG+ + +IVE+ D ++ E+ D+ P PPP P P P PQ
Sbjct: 117 EGSKNIRLGSLIGLIVEEGED------WKHVEIPKDVGP--PPPVSKPSEPRPSPEPQIS 168
Query: 337 APTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVP-- 394
P P T R +SP A+ + + +D +Q TGP G TK+D V
Sbjct: 169 IPVKKEHIPGTL-----RFRLSPAARNILEKHSLDASQGTATGPRGIFTKEDALKLVQLK 223
Query: 395 -------SKVAPAPAA-------------------VVPPTGPGMAPVPTGVFTDIPISNI 428
S+ PAP A V+PP P G FT+IP SNI
Sbjct: 224 QTGKITESRPTPAPTATPTAPSPLQATAGPSYPRPVIPPVSTPGQPNAVGTFTEIPASNI 283
Query: 429 RRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRSKISVNDFIIKASALAC 488
RRVIA+RL +SK T+PH Y + D ++G VL VR++L K K+SVNDFIIKA+A+
Sbjct: 284 RRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVK---DDIKVSVNDFIIKAAAVTL 340
Query: 489 LKVPEANSSWMDTVIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKA 548
++P+ N SW +Q +D+SVAV+T GL+TPI+ +A KG++ IA+ V +L+ KA
Sbjct: 341 KQMPDVNVSWDGEGPKQLPFIDISVAVATDKGLLTPIIKDAAAKGIQEIADSVKALSKKA 400
Query: 549 REGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDKLVPADNEKG--- 605
R+GKL P E+QGG+F+ISNLGMFGI F+A+INPPQACILA+G L ++E+G
Sbjct: 401 RDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKLTEDEEGNAK 460
Query: 606 FDVASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITM 645
+++VT+S D RVVD + ++L F+ LE PI +
Sbjct: 461 LQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENPIRL 500
Score = 95.9 bits (237), Expect = 1e-19
Identities = 98/352 (27%), Positives = 144/352 (40%), Gaps = 76/352 (21%)
Query: 42 PARRNSVTTGYGGVRALCGWTPSSGATPRNRLLLQLL-GSPGRRYYSLPPHQKVPLPSLS 100
P RR+ G V+ GW+ S GA R Q L G P K+ +PSLS
Sbjct: 21 PGRRS-----VGLVKGALGWSVSRGANWRWFHSTQWLRGDP----------IKILMPSLS 65
Query: 101 PTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEGTRDVPIG 160
PTM+ G I +W KKEG+ ++ GD + E+ETDKA V ++ ++ +AKI+V EG++++ +G
Sbjct: 66 PTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLDASDDGILAKIVVEEGSKNIRLG 125
Query: 161 AIICITVGKPEDIEAFKNYTLDSSAAPTPQAA----PAPTPAATASPPTPSAQAPGSSYP 216
++I + V + ED +K+ + P P + P P+P S P PG+
Sbjct: 126 SLIGLIVEEGED---WKHVEIPKDVGPPPPVSKPSEPRPSPEPQISIPVKKEHIPGT--- 179
Query: 217 PHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKIL 276
L LSP + + EK S +
Sbjct: 180 -----LRFRLSPA---------ARNILEKHS---------------------------LD 198
Query: 277 VPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVP--PTPQ 334
+GT P G I KE + + ++T+ +P P PT P A P T
Sbjct: 199 ASQGTATGPRG-----IFTKEDALKLVQLKQTGKITESRP-TPAPTATPTAPSPLQATAG 252
Query: 335 PLAPTPSAPCPATPAGPKG-RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRIT 385
P P P P +TP P F A + LT+ K T P T
Sbjct: 253 PSYPRPVIPPVSTPGQPNAVGTFTEIPASNIRRVIAKRLTESKSTVPHAYAT 304
>gi|19923748 dihydrolipoamide S-succinyltransferase (E2 component of
2-oxo-glutarate complex) [Homo sapiens]
Length = 453
Score = 158 bits (399), Expect = 2e-38
Identities = 127/431 (29%), Positives = 196/431 (45%), Gaps = 56/431 (12%)
Query: 221 VLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEG 280
V PA + ++T G V RWEK VG+ ++E +++ EIETDK ++ G + +LVP+G
Sbjct: 73 VKTPAFAESVTEGDV-RWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG 131
Query: 281 TRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTP 340
+ V GTPL + + A A A +P E P P AAVPP P+ PT
Sbjct: 132 GK-VEGGTPLFTLRKTGA---APAKAKPAEAP---AAAAPKAEPTAAAVPPPAAPI-PTQ 183
Query: 341 SAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPA 400
P P+ P G K + + P+ A
Sbjct: 184 MPPVPSPSQPPSG---------------------------------KPVSAVKPTV---A 207
Query: 401 PAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLV 460
P P G G+ ++ +R+ IAQRL +++ T +++M + +
Sbjct: 208 PPLAEPGAGKGLRSEHRE-----KMNRMRQRIAQRLKEAQNTCAMLTTFNEIDMSNIQEM 262
Query: 461 RKELNK--ILEGRSKISVNDFIIKASALACLKVPEANSSWMDTV--IRQNHVVDVSVAVS 516
R + + + K+ +KASA A + P N+ DT + +D+SVAV+
Sbjct: 263 RARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVYRDYIDISVAVA 322
Query: 517 TPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNF 576
TP GL+ P++ N I + L KAR+ +L + GGTFTISN G+FG
Sbjct: 323 TPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTISNGGVFGSLFG 382
Query: 577 SAIINPPQACILAIGASEDKLVPADNEKGFDVASMMSVTLSCDHRVVDGAVGAQWLAEFR 636
+ IINPPQ+ IL + D+ V + +V MM V L+ DHR++DG +L + +
Sbjct: 383 TPIINPPQSAILGMHGIFDRPVAIGGK--VEVRPMMYVALTYDHRLIDGREAVTFLRKIK 440
Query: 637 KYLEKPITMLL 647
+E P +LL
Sbjct: 441 AAVEDPRVLLL 451
Score = 55.8 bits (133), Expect = 1e-07
Identities = 45/143 (31%), Positives = 68/143 (47%), Gaps = 11/143 (7%)
Query: 94 VPLPSLSPTMQAGTIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKILVAEG 153
V P+ + ++ G + RWEK GD + E +++ E+ETDK +V S + +LV +G
Sbjct: 73 VKTPAFAESVTEGDV-RWEKAVGDTVAEDEVVCEIETDKTSVQVPSPANGVIEALLVPDG 131
Query: 154 TRDVPIGAIICITVGKPEDIEA-FKNYTLDSSAAP--TPQAAPAPTPAA---TASPPTPS 207
+ G T+ K A K ++AAP P AA P PAA T PP PS
Sbjct: 132 GK--VEGGTPLFTLRKTGAAPAKAKPAEAPAAAAPKAEPTAAAVPPPAAPIPTQMPPVPS 189
Query: 208 AQAPGSSYPPHMQVLLPALSPTM 230
P S P + + P ++P +
Sbjct: 190 PSQPPSGKP--VSAVKPTVAPPL 210
>gi|110671329 dihydrolipoamide branched chain transacylase precursor
[Homo sapiens]
Length = 482
Score = 154 bits (388), Expect = 3e-37
Identities = 127/437 (29%), Positives = 211/437 (48%), Gaps = 60/437 (13%)
Query: 234 TVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVP-LGTPLCI 292
TV+ W K G+ +S+ D + E+++DKA++ + +G + K+ D+ +G PL +
Sbjct: 80 TVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYY--NLDDIAYVGKPL-V 136
Query: 293 IVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPK 352
+E EA + D T P V+ T Q + K
Sbjct: 137 DIETEALKDSEEDVVET--------------PAVSHDEHTHQEI---------------K 167
Query: 353 GR-VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVA----PAPAAVVPP 407
GR +P ++LA+E I L++V G+G DGRI K+DI +++ + P+P + P
Sbjct: 168 GRKTLATPAVRRLAMENNIKLSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMP 227
Query: 408 TGP-----------GMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGE 456
P PV TG PI ++ + + M + IPH+ ++++ E
Sbjct: 228 PPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQKAMV-KTMSAALKIPHFGYCDEIDLTE 286
Query: 457 VLLVRKELNKILEGRS-KISVNDFIIKASALACLKVPEANSS----WMDTVIRQNHVVDV 511
++ +R+EL I R K+S F +KA++L L+ P N+S + + +H ++
Sbjct: 287 LVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPILNASVDENCQNITYKASH--NI 344
Query: 512 SVAVSTPAGLITPIVFNAHIKGVETIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMF 571
+A+ T GLI P V N I + IA ++ L +L + GGTFT+SN+G
Sbjct: 345 GIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSI 404
Query: 572 GIKNFSAIINPPQACILAIGASEDKLVPADNEKG-FDVASMMSVTLSCDHRVVDGAVGAQ 630
G +I PP+ I A+G+ K +P N+KG A +M+V+ S DHRV+DGA ++
Sbjct: 405 GGTFAKPVIMPPEVAIGALGSI--KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSR 462
Query: 631 WLAEFRKYLEKPITMLL 647
+ ++ YLE P MLL
Sbjct: 463 FSNLWKSYLENPAFMLL 479
Score = 35.4 bits (80), Expect = 0.16
Identities = 16/42 (38%), Positives = 26/42 (61%)
Query: 107 TIARWEKKEGDKINEGDLIAEVETDKATVGFESLEECYMAKI 148
T+ W KEGD +++ D I EV++DKA+V S + + K+
Sbjct: 80 TVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKL 121
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 48.9 bits (115), Expect = 1e-05
Identities = 19/36 (52%), Positives = 22/36 (61%)
Query: 316 PQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGP 351
P PPP PPP +A PP P P P P++P P P GP
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGP 719
Score = 36.6 bits (83), Expect = 0.074
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Query: 319 PPPTPPPVAAVPPTPQPLAPTPSAPCPA-TPAGPKGRVF 356
PPP PPP+ P P P P P+ P P P P G F
Sbjct: 700 PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFF 738
Score = 35.8 bits (81), Expect = 0.13
Identities = 17/33 (51%), Positives = 19/33 (57%), Gaps = 1/33 (3%)
Query: 319 PPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGP 351
P P PPV+A PP P P P P P P + AGP
Sbjct: 667 PAPPMPPVSAGPPLPPPPPPPPPLP-PPSSAGP 698
Score = 33.5 bits (75), Expect = 0.63
Identities = 17/45 (37%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPL---APTPSAPCPATPA 349
P P PPP PPP PP P L + S+ CP PA
Sbjct: 708 PNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPA 752
Score = 32.7 bits (73), Expect = 1.1
Identities = 16/37 (43%), Positives = 17/37 (45%), Gaps = 2/37 (5%)
Query: 316 PQVPPPTPPPVAAVPPTP--QPLAPTPSAPCPATPAG 350
P PPP P P + PP P P AP P P P G
Sbjct: 699 PPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
Score = 32.3 bits (72), Expect = 1.4
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 2/29 (6%)
Query: 320 PPTPPPVAAVPPTPQPLAPTPSAPCPATP 348
PP PPP +P +P P P P P PA P
Sbjct: 698 PPPPPPPPPLPNSPAP--PNPGGPPPAPP 724
Score = 32.0 bits (71), Expect = 1.8
Identities = 43/178 (24%), Positives = 67/178 (37%), Gaps = 29/178 (16%)
Query: 293 IVEKEADISAFADYRP-TEVTDLKPQVPP----------PTPPPVAAVPPTPQPL----- 336
+V K+ +IS+ + P + D+ + P PPP A++PP P PL
Sbjct: 605 LVPKKLNISSLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPP-PPPLPSGLG 663
Query: 337 APTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSK 396
+ +P+ P P AGP PL + G P P+
Sbjct: 664 SLSPAPPMPPVSAGP-------PLPPPPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNP 716
Query: 397 VAPAPAAVVPPTGPGMA-PVPTGVFTDIPISNIRRVIAQRLMQSKQTIPHYYLSIDVN 453
P PA P PG+A P P G+F + S+ + + S P Y+ I ++
Sbjct: 717 GGPPPA----PPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYWTRIQIS 770
Score = 30.8 bits (68), Expect = 4.1
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 4/39 (10%)
Query: 183 SSAAPTPQAAPAPTPAATASP----PTPSAQAPGSSYPP 217
SSA P P P P P + A P P P+ PG + PP
Sbjct: 694 SSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPP 732
>gi|149363685 hypothetical protein LOC23379 [Homo sapiens]
Length = 2266
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/62 (41%), Positives = 37/62 (59%), Gaps = 4/62 (6%)
Query: 298 ADISAFADYRPTEVTDLKPQVPPPTPP---PVAAVPP-TPQPLAPTPSAPCPATPAGPKG 353
AD S D P ++ ++ +V PP PP P+ A PP T QPL+P S+ P++PA P G
Sbjct: 1608 ADTSTPTDCSPDTLSKIRQEVGPPLPPLLAPLIATPPRTSQPLSPLISSSSPSSPASPVG 1667
Query: 354 RV 355
+V
Sbjct: 1668 QV 1669
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 76/237 (32%), Gaps = 26/237 (10%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT +P TP AP + P PA PT
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTP 361
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
K+ + + T E P T+ P T E
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEP----------APTTTKSAPTTTK-----EPAPT 406
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPT-PSAPCPATPAGPKGRVFVS 358
+ A P E + + P PT P A P TP+ APT P P P TP P
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465
Query: 359 PLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGMAP 414
P K T K T P T K + P K+AP P P T +AP
Sbjct: 466 PAP---TTPKEPAPTTPKETAP---TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516
Score = 47.4 bits (111), Expect = 4e-05
Identities = 68/253 (26%), Positives = 84/253 (33%), Gaps = 53/253 (20%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T PT PAPT A+P TP AP + P +PT
Sbjct: 517 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP---------APTTPKEPAPTTP 567
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEA- 298
K ET T P+GT L P +K A
Sbjct: 568 K---------------ETAPTT----------------PKGTAPTTLKEPAPTTPKKPAP 596
Query: 299 -DISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP-TPSAPCPATPAG--PKGR 354
+++ PT T KP P TP A P TP+ AP TP P P TP G P
Sbjct: 597 KELAPTTTKEPTSTTCDKP--APTTPKGTA--PTTPKEPAPTTPKEPAPTTPKGTAPTTL 652
Query: 355 VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
+P K K + T K GP + K + P + AP PT P P
Sbjct: 653 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKP 708
Query: 415 VPTGVFTDIPISN 427
PT T P ++
Sbjct: 709 APTTPETPPPTTS 721
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/242 (27%), Positives = 79/242 (32%), Gaps = 27/242 (11%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT SP TP AP ++ PA + T + T +
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 240 KKVGEKLSEGDLLAEIE--TDKATIGFEVQEEGYLA-KILVPEGTRDVPLGTPLCIIVEK 296
K E T K +E K P T+ TP K
Sbjct: 419 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP------K 472
Query: 297 EADISAFADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPT-PSAPCPATPAGPKG 353
E + + PT L P P P P P TP+ LAPT P P P TP P
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-- 530
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGM 412
+P K A K P T K+ P + AP P P T G
Sbjct: 531 ----APTTPKAAAP-----NTPKEPAP---TTPKEPAPTTPKEPAPTTPKETAPTTPKGT 578
Query: 413 AP 414
AP
Sbjct: 579 AP 580
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/236 (25%), Positives = 80/236 (33%), Gaps = 14/236 (5%)
Query: 188 TPQAAPAPTPAATASPPTPSAQA--PGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEK 245
TP + + SP +A+ P S PP+ TV+ E K
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 160
Query: 246 LSEGDLLAEIETDKATIGFEVQE-EGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
+ D +K T E Q E AK L P ++ + TP K ++
Sbjct: 161 QTSTD-----GKEKTTSAKETQSIEKTSAKDLAPT-SKVLAKPTPKAETTTKGPALTTPK 214
Query: 305 DYRPTEVTDLKPQVPP-PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
+ PT + P PTP + + P TP+ APT + P TP P P A
Sbjct: 215 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APT 273
Query: 364 LAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
E T+ T T K+ P K AP PT P P PT
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPT 328
Score = 37.0 bits (84), Expect = 0.057
Identities = 65/263 (24%), Positives = 88/263 (33%), Gaps = 46/263 (17%)
Query: 166 TVGKPEDIEAFKNYTLDSSAA----PTPQAAPAPTPAATASPPTPSAQAPGSSYP--PHM 219
T GK + A + +++ ++A PT + PTP A + P+ P P P
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 223
Query: 220 QVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPE 279
PT T + + T K + K P
Sbjct: 224 PASTTPKEPTPTT------------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPT 265
Query: 280 GTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLK--PQVPPPTPPPVAAVPPTPQPLA 337
T++ TP KE + + PT P+ P PT P A P TP+ A
Sbjct: 266 TTKEPAPTTP------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPA 318
Query: 338 PT-PSAPCPATPAGPKGRVFVSPLAKKLA--VEKGIDLTQVKGTGPDGRITKKDIDSFVP 394
PT P P P TP P +P K+ A K T K P T K+ P
Sbjct: 319 PTTPKEPTPTTPKEP------APTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTP 369
Query: 395 SKVAPAPAAVVPPTGPGMAPVPT 417
+ AP PT P P PT
Sbjct: 370 KEPAPTTTKEPSPTTP-KEPAPT 391
Score = 36.6 bits (83), Expect = 0.074
Identities = 63/260 (24%), Positives = 80/260 (30%), Gaps = 40/260 (15%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS-SYPPHMQVLLPA---LSPTMTMGTV 235
T APT PAPT +P TP AP + P PA L+PT T
Sbjct: 549 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 608
Query: 236 QRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVE 295
K +G + T E P+GT L P +
Sbjct: 609 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT-------TPKGTAPTTLKEPAPTTPK 661
Query: 296 KEA--DISAFADYRPTEVTDLKP-------------QVPPPTPP--PVAAVPPTPQPLAP 338
K A +++ PT T KP + P PT P P P TP P
Sbjct: 662 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 721
Query: 339 TPSAPC----PAT----PAGPKGRVFVSPLAKKL---AVEKGIDLTQV-KGTGPDGRITK 386
S P P T P + P K L E G+ T+ T P+ T
Sbjct: 722 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 781
Query: 387 KDIDSFVPSKVAPAPAAVVP 406
KD + + P P
Sbjct: 782 KDKTTERDLRTTPETTTAAP 801
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 76/237 (32%), Gaps = 26/237 (10%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT +P TP AP + P PA PT
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTP 402
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
K+ + + T E P T+ P T E
Sbjct: 403 KEPAPTTPKEPAPTTTKEPSPTTPKEP----------APTTTKSAPTTTK-----EPAPT 447
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPT-PSAPCPATPAGPKGRVFVS 358
+ A P E + + P PT P A P TP+ APT P P P TP P
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506
Query: 359 PLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGMAP 414
P K T K T P T K + P K+AP P P T +AP
Sbjct: 507 PAP---TTPKEPAPTTPKETAP---TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557
Score = 47.4 bits (111), Expect = 4e-05
Identities = 68/253 (26%), Positives = 84/253 (33%), Gaps = 53/253 (20%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T PT PAPT A+P TP AP + P +PT
Sbjct: 558 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP---------APTTPKEPAPTTP 608
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEA- 298
K ET T P+GT L P +K A
Sbjct: 609 K---------------ETAPTT----------------PKGTAPTTLKEPAPTTPKKPAP 637
Query: 299 -DISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP-TPSAPCPATPAG--PKGR 354
+++ PT T KP P TP A P TP+ AP TP P P TP G P
Sbjct: 638 KELAPTTTKEPTSTTCDKP--APTTPKGTA--PTTPKEPAPTTPKEPAPTTPKGTAPTTL 693
Query: 355 VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
+P K K + T K GP + K + P + AP PT P P
Sbjct: 694 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKP 749
Query: 415 VPTGVFTDIPISN 427
PT T P ++
Sbjct: 750 APTTPETPPPTTS 762
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/242 (27%), Positives = 79/242 (32%), Gaps = 27/242 (11%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT SP TP AP ++ PA + T + T +
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 240 KKVGEKLSEGDLLAEIE--TDKATIGFEVQEEGYLA-KILVPEGTRDVPLGTPLCIIVEK 296
K E T K +E K P T+ TP K
Sbjct: 460 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP------K 513
Query: 297 EADISAFADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPT-PSAPCPATPAGPKG 353
E + + PT L P P P P P TP+ LAPT P P P TP P
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-- 571
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGM 412
+P K A K P T K+ P + AP P P T G
Sbjct: 572 ----APTTPKAAAP-----NTPKEPAP---TTPKEPAPTTPKEPAPTTPKETAPTTPKGT 619
Query: 413 AP 414
AP
Sbjct: 620 AP 621
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/236 (25%), Positives = 80/236 (33%), Gaps = 14/236 (5%)
Query: 188 TPQAAPAPTPAATASPPTPSAQA--PGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEK 245
TP + + SP +A+ P S PP+ TV+ E K
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 201
Query: 246 LSEGDLLAEIETDKATIGFEVQE-EGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
+ D +K T E Q E AK L P ++ + TP K ++
Sbjct: 202 QTSTD-----GKEKTTSAKETQSIEKTSAKDLAPT-SKVLAKPTPKAETTTKGPALTTPK 255
Query: 305 DYRPTEVTDLKPQVPP-PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
+ PT + P PTP + + P TP+ APT + P TP P P A
Sbjct: 256 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APT 314
Query: 364 LAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
E T+ T T K+ P K AP PT P P PT
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPT 369
Score = 37.0 bits (84), Expect = 0.057
Identities = 65/263 (24%), Positives = 88/263 (33%), Gaps = 46/263 (17%)
Query: 166 TVGKPEDIEAFKNYTLDSSAA----PTPQAAPAPTPAATASPPTPSAQAPGSSYP--PHM 219
T GK + A + +++ ++A PT + PTP A + P+ P P P
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 264
Query: 220 QVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPE 279
PT T + + T K + K P
Sbjct: 265 PASTTPKEPTPTT------------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPT 306
Query: 280 GTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLK--PQVPPPTPPPVAAVPPTPQPLA 337
T++ TP KE + + PT P+ P PT P A P TP+ A
Sbjct: 307 TTKEPAPTTP------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPA 359
Query: 338 PT-PSAPCPATPAGPKGRVFVSPLAKKLA--VEKGIDLTQVKGTGPDGRITKKDIDSFVP 394
PT P P P TP P +P K+ A K T K P T K+ P
Sbjct: 360 PTTPKEPTPTTPKEP------APTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTP 410
Query: 395 SKVAPAPAAVVPPTGPGMAPVPT 417
+ AP PT P P PT
Sbjct: 411 KEPAPTTTKEPSPTTP-KEPAPT 432
Score = 36.6 bits (83), Expect = 0.074
Identities = 63/260 (24%), Positives = 80/260 (30%), Gaps = 40/260 (15%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS-SYPPHMQVLLPA---LSPTMTMGTV 235
T APT PAPT +P TP AP + P PA L+PT T
Sbjct: 590 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 649
Query: 236 QRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVE 295
K +G + T E P+GT L P +
Sbjct: 650 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT-------TPKGTAPTTLKEPAPTTPK 702
Query: 296 KEA--DISAFADYRPTEVTDLKP-------------QVPPPTPP--PVAAVPPTPQPLAP 338
K A +++ PT T KP + P PT P P P TP P
Sbjct: 703 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 762
Query: 339 TPSAPC----PAT----PAGPKGRVFVSPLAKKL---AVEKGIDLTQV-KGTGPDGRITK 386
S P P T P + P K L E G+ T+ T P+ T
Sbjct: 763 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 822
Query: 387 KDIDSFVPSKVAPAPAAVVP 406
KD + + P P
Sbjct: 823 KDKTTERDLRTTPETTTAAP 842
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 76/237 (32%), Gaps = 26/237 (10%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT +P TP AP + P PA PT
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTP 454
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
K+ + + T E P T+ P T E
Sbjct: 455 KEPAPTTPKEPAPTTTKEPSPTTPKEP----------APTTTKSAPTTTK-----EPAPT 499
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPT-PSAPCPATPAGPKGRVFVS 358
+ A P E + + P PT P A P TP+ APT P P P TP P
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 558
Query: 359 PLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGMAP 414
P K T K T P T K + P K+AP P P T +AP
Sbjct: 559 PAP---TTPKEPAPTTPKETAP---TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609
Score = 47.4 bits (111), Expect = 4e-05
Identities = 68/253 (26%), Positives = 84/253 (33%), Gaps = 53/253 (20%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T PT PAPT A+P TP AP + P +PT
Sbjct: 610 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP---------APTTPKEPAPTTP 660
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEA- 298
K ET T P+GT L P +K A
Sbjct: 661 K---------------ETAPTT----------------PKGTAPTTLKEPAPTTPKKPAP 689
Query: 299 -DISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP-TPSAPCPATPAG--PKGR 354
+++ PT T KP P TP A P TP+ AP TP P P TP G P
Sbjct: 690 KELAPTTTKEPTSTTCDKP--APTTPKGTA--PTTPKEPAPTTPKEPAPTTPKGTAPTTL 745
Query: 355 VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
+P K K + T K GP + K + P + AP PT P P
Sbjct: 746 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKP 801
Query: 415 VPTGVFTDIPISN 427
PT T P ++
Sbjct: 802 APTTPETPPPTTS 814
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/242 (27%), Positives = 79/242 (32%), Gaps = 27/242 (11%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT SP TP AP ++ PA + T + T +
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 240 KKVGEKLSEGDLLAEIE--TDKATIGFEVQEEGYLA-KILVPEGTRDVPLGTPLCIIVEK 296
K E T K +E K P T+ TP K
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP------K 565
Query: 297 EADISAFADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPT-PSAPCPATPAGPKG 353
E + + PT L P P P P P TP+ LAPT P P P TP P
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-- 623
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGM 412
+P K A K P T K+ P + AP P P T G
Sbjct: 624 ----APTTPKAAAP-----NTPKEPAP---TTPKEPAPTTPKEPAPTTPKETAPTTPKGT 671
Query: 413 AP 414
AP
Sbjct: 672 AP 673
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/236 (25%), Positives = 80/236 (33%), Gaps = 14/236 (5%)
Query: 188 TPQAAPAPTPAATASPPTPSAQA--PGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEK 245
TP + + SP +A+ P S PP+ TV+ E K
Sbjct: 194 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 253
Query: 246 LSEGDLLAEIETDKATIGFEVQE-EGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
+ D +K T E Q E AK L P ++ + TP K ++
Sbjct: 254 QTSTD-----GKEKTTSAKETQSIEKTSAKDLAPT-SKVLAKPTPKAETTTKGPALTTPK 307
Query: 305 DYRPTEVTDLKPQVPP-PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
+ PT + P PTP + + P TP+ APT + P TP P P A
Sbjct: 308 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APT 366
Query: 364 LAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
E T+ T T K+ P K AP PT P P PT
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPT 421
Score = 37.0 bits (84), Expect = 0.057
Identities = 65/263 (24%), Positives = 88/263 (33%), Gaps = 46/263 (17%)
Query: 166 TVGKPEDIEAFKNYTLDSSAA----PTPQAAPAPTPAATASPPTPSAQAPGSSYP--PHM 219
T GK + A + +++ ++A PT + PTP A + P+ P P P
Sbjct: 257 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 316
Query: 220 QVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPE 279
PT T + + T K + K P
Sbjct: 317 PASTTPKEPTPTT------------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPT 358
Query: 280 GTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLK--PQVPPPTPPPVAAVPPTPQPLA 337
T++ TP KE + + PT P+ P PT P A P TP+ A
Sbjct: 359 TTKEPAPTTP------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPA 411
Query: 338 PT-PSAPCPATPAGPKGRVFVSPLAKKLA--VEKGIDLTQVKGTGPDGRITKKDIDSFVP 394
PT P P P TP P +P K+ A K T K P T K+ P
Sbjct: 412 PTTPKEPTPTTPKEP------APTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTP 462
Query: 395 SKVAPAPAAVVPPTGPGMAPVPT 417
+ AP PT P P PT
Sbjct: 463 KEPAPTTTKEPSPTTP-KEPAPT 484
Score = 36.6 bits (83), Expect = 0.074
Identities = 63/260 (24%), Positives = 80/260 (30%), Gaps = 40/260 (15%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS-SYPPHMQVLLPA---LSPTMTMGTV 235
T APT PAPT +P TP AP + P PA L+PT T
Sbjct: 642 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 701
Query: 236 QRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVE 295
K +G + T E P+GT L P +
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT-------TPKGTAPTTLKEPAPTTPK 754
Query: 296 KEA--DISAFADYRPTEVTDLKP-------------QVPPPTPP--PVAAVPPTPQPLAP 338
K A +++ PT T KP + P PT P P P TP P
Sbjct: 755 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 814
Query: 339 TPSAPC----PAT----PAGPKGRVFVSPLAKKL---AVEKGIDLTQV-KGTGPDGRITK 386
S P P T P + P K L E G+ T+ T P+ T
Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874
Query: 387 KDIDSFVPSKVAPAPAAVVP 406
KD + + P P
Sbjct: 875 KDKTTERDLRTTPETTTAAP 894
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 48.5 bits (114), Expect = 2e-05
Identities = 63/237 (26%), Positives = 76/237 (32%), Gaps = 26/237 (10%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT +P TP AP + P PA PT
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA--PTAPKKPAPTTP 495
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
K+ + + T E P T+ P T E
Sbjct: 496 KEPAPTTPKEPAPTTTKEPSPTTPKEP----------APTTTKSAPTTTK-----EPAPT 540
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPT-PSAPCPATPAGPKGRVFVS 358
+ A P E + + P PT P A P TP+ APT P P P TP P
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 599
Query: 359 PLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGMAP 414
P K T K T P T K + P K+AP P P T +AP
Sbjct: 600 PAP---TTPKEPAPTTPKETAP---TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650
Score = 47.4 bits (111), Expect = 4e-05
Identities = 68/253 (26%), Positives = 84/253 (33%), Gaps = 53/253 (20%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T PT PAPT A+P TP AP + P +PT
Sbjct: 651 TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP---------APTTPKEPAPTTP 701
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEA- 298
K ET T P+GT L P +K A
Sbjct: 702 K---------------ETAPTT----------------PKGTAPTTLKEPAPTTPKKPAP 730
Query: 299 -DISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP-TPSAPCPATPAG--PKGR 354
+++ PT T KP P TP A P TP+ AP TP P P TP G P
Sbjct: 731 KELAPTTTKEPTSTTCDKP--APTTPKGTA--PTTPKEPAPTTPKEPAPTTPKGTAPTTL 786
Query: 355 VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
+P K K + T K GP + K + P + AP PT P P
Sbjct: 787 KEPAPTTPKKPAPKELAPTTTK--GPTSTTSDKPAPT-TPKETAPTTPKEPAPTTP-KKP 842
Query: 415 VPTGVFTDIPISN 427
PT T P ++
Sbjct: 843 APTTPETPPPTTS 855
Score = 46.2 bits (108), Expect = 9e-05
Identities = 66/242 (27%), Positives = 79/242 (32%), Gaps = 27/242 (11%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APT PAPT SP TP AP ++ PA + T + T +
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 240 KKVGEKLSEGDLLAEIE--TDKATIGFEVQEEGYLA-KILVPEGTRDVPLGTPLCIIVEK 296
K E T K +E K P T+ TP K
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP------K 606
Query: 297 EADISAFADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPT-PSAPCPATPAGPKG 353
E + + PT L P P P P P TP+ LAPT P P P TP P
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-- 664
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVPPTGPGM 412
+P K A K P T K+ P + AP P P T G
Sbjct: 665 ----APTTPKAAAP-----NTPKEPAP---TTPKEPAPTTPKEPAPTTPKETAPTTPKGT 712
Query: 413 AP 414
AP
Sbjct: 713 AP 714
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/236 (25%), Positives = 80/236 (33%), Gaps = 14/236 (5%)
Query: 188 TPQAAPAPTPAATASPPTPSAQA--PGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEK 245
TP + + SP +A+ P S PP+ TV+ E K
Sbjct: 235 TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 294
Query: 246 LSEGDLLAEIETDKATIGFEVQE-EGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
+ D +K T E Q E AK L P ++ + TP K ++
Sbjct: 295 QTSTD-----GKEKTTSAKETQSIEKTSAKDLAPT-SKVLAKPTPKAETTTKGPALTTPK 348
Query: 305 DYRPTEVTDLKPQVPP-PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
+ PT + P PTP + + P TP+ APT + P TP P P A
Sbjct: 349 EPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-APT 407
Query: 364 LAVEKGIDLTQ--VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
E T+ T T K+ P K AP PT P P PT
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP-KEPTPT 462
Score = 37.0 bits (84), Expect = 0.057
Identities = 65/263 (24%), Positives = 88/263 (33%), Gaps = 46/263 (17%)
Query: 166 TVGKPEDIEAFKNYTLDSSAA----PTPQAAPAPTPAATASPPTPSAQAPGSSYP--PHM 219
T GK + A + +++ ++A PT + PTP A + P+ P P P
Sbjct: 298 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE 357
Query: 220 QVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPE 279
PT T + + T K + K P
Sbjct: 358 PASTTPKEPTPTT------------------IKSAPTTPKEPAPTTTKSAPTTPKEPAPT 399
Query: 280 GTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLK--PQVPPPTPPPVAAVPPTPQPLA 337
T++ TP KE + + PT P+ P PT P A P TP+ A
Sbjct: 400 TTKEPAPTTP------KEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA-PTTPKEPA 452
Query: 338 PT-PSAPCPATPAGPKGRVFVSPLAKKLA--VEKGIDLTQVKGTGPDGRITKKDIDSFVP 394
PT P P P TP P +P K+ A K T K P T K+ P
Sbjct: 453 PTTPKEPTPTTPKEP------APTTKEPAPTTPKEPAPTAPKKPAP---TTPKEPAPTTP 503
Query: 395 SKVAPAPAAVVPPTGPGMAPVPT 417
+ AP PT P P PT
Sbjct: 504 KEPAPTTTKEPSPTTP-KEPAPT 525
Score = 36.6 bits (83), Expect = 0.074
Identities = 63/260 (24%), Positives = 80/260 (30%), Gaps = 40/260 (15%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS-SYPPHMQVLLPA---LSPTMTMGTV 235
T APT PAPT +P TP AP + P PA L+PT T
Sbjct: 683 TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPT 742
Query: 236 QRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVE 295
K +G + T E P+GT L P +
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPT-------TPKGTAPTTLKEPAPTTPK 795
Query: 296 KEA--DISAFADYRPTEVTDLKP-------------QVPPPTPP--PVAAVPPTPQPLAP 338
K A +++ PT T KP + P PT P P P TP P
Sbjct: 796 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 855
Query: 339 TPSAPC----PAT----PAGPKGRVFVSPLAKKL---AVEKGIDLTQV-KGTGPDGRITK 386
S P P T P + P K L E G+ T+ T P+ T
Sbjct: 856 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915
Query: 387 KDIDSFVPSKVAPAPAAVVP 406
KD + + P P
Sbjct: 916 KDKTTERDLRTTPETTTAAP 935
>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
1 [Homo sapiens]
Length = 828
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/142 (31%), Positives = 59/142 (41%), Gaps = 14/142 (9%)
Query: 285 PLGTPLCIIVEKEADISAFADYRPTEVT-DLKPQ---VPPPTPPPVAAVPPTPQPLAPTP 340
P+ +P + V E F+D P VT +L P+ V PP P A P P PL P
Sbjct: 297 PVLSPKSVAVNAEEKWVHFSDTSPEHVTPELTPREKVVSPPATPDNPADSPAPGPLGP-- 354
Query: 341 SAPCPATPAGPKG--RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDID----SFVP 394
P P P GP G R +SPL + +K + T +K + + KD + P
Sbjct: 355 --PGPTGPPGPPGPPRNVLSPLNLEEVQKKVAEQTFIKDDYLETISSPKDFGLGQRATPP 412
Query: 395 SKVAPAPAAVVPPTGPGMAPVP 416
P VV GPG P P
Sbjct: 413 PPPPPTYRTVVSSPGPGSGPGP 434
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 47.8 bits (112), Expect = 3e-05
Identities = 38/134 (28%), Positives = 53/134 (39%), Gaps = 27/134 (20%)
Query: 314 LKPQVPPPTPPPVAAVPP------------TPQPLAPTPSAPCPATPAGPKGRVFVSPLA 361
L P PPP PPP A P +PQPL P P P A P PLA
Sbjct: 67 LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPL---------PLA 117
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTG--PGMAPVPTGV 419
+ G +K P ++ + + P+ + P A +PP G + P+PT V
Sbjct: 118 PRQPALVGAPGLSIKEPAP--LPSRPQVPT--PAPLLPDSKATIPPNGSPKPLQPLPTPV 173
Query: 420 FTDIPISNIRRVIA 433
T P ++ +A
Sbjct: 174 LTIAPHPGVQPQLA 187
Score = 30.4 bits (67), Expect = 5.3
Identities = 33/107 (30%), Positives = 39/107 (36%), Gaps = 12/107 (11%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVE 367
P V PQ PP PP AA P PLAP A A K +PL + V
Sbjct: 90 PIPVVTNSPQPLPPPPPLPAAAQPL--PLAPRQPALVGAPGLSIKE---PAPLPSRPQVP 144
Query: 368 KGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
L PD + T S P + P P + P PG+ P
Sbjct: 145 TPAPLL------PDSKATIPPNGSPKPLQPLPTPVLTIAP-HPGVQP 184
Score = 29.6 bits (65), Expect = 9.0
Identities = 30/103 (29%), Positives = 40/103 (38%), Gaps = 13/103 (12%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVE 367
P + + + P P PPP A P Q L P P A AT G + + ++
Sbjct: 397 PVQQQQPQQKTPLPAPPPPPAAP--AQTLVPAP-AHLVATAGGGSTVIAHTATTHASVIQ 453
Query: 368 KGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGP 410
+ Q GP G K I PS AP+PA + P P
Sbjct: 454 TVNHVLQ----GPGG----KHIAHIAPS--APSPAVQLAPATP 486
>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
Length = 3859
Score = 47.4 bits (111), Expect = 4e-05
Identities = 62/236 (26%), Positives = 87/236 (36%), Gaps = 39/236 (16%)
Query: 196 TPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEI 255
TPA T P P A P ++PA SP + + + V ++ + I
Sbjct: 791 TPADTNGPAVPVTSADSPFVP-----VIPADSPVVPVTPAD--DPIVPVTPADSSFVPVI 843
Query: 256 ETDKATIGFEVQEEGYLAKILVPEGTRDV---PLGTPLCIIVEKEADISAFADYRPTEVT 312
D + + +G + V + + DV P+ CI+V AFAD +
Sbjct: 844 SADSPFVPV-IPADGPV----VVDSSTDVLVVPVFPVNCILVP------AFADETVVPLN 892
Query: 313 DLKPQVPPPTPPPVAAVPPTPQ--PLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGI 370
V P TPP VP TP P+AP SA CP P P SP A +
Sbjct: 893 PADSPVIPVTPPDDLVVPVTPTDCPVAPVTSADCPVVPVTPAD----SPADPVTAAD--- 945
Query: 371 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPIS 426
GP T D D VP A +P V P + PV + +P++
Sbjct: 946 --------GPVVPFTPAD-DPIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVT 992
Score = 41.2 bits (95), Expect = 0.003
Identities = 81/302 (26%), Positives = 115/302 (38%), Gaps = 61/302 (20%)
Query: 168 GKPEDIEAFKNYTLDSSAAPTPQAAPAP------TPAATASPPTP----------SAQAP 211
G P+ I AF S+ +P + PA TPA A P S P
Sbjct: 2866 GVPDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADCADVPVNPVNGPVVPDLSGDCP 2925
Query: 212 GSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQ---E 268
PP +++ L+P + V V +++G ++ TD AT G V
Sbjct: 2926 VVPVPPTDDIVV--LNPPDVVFAV------VSTPVTDGPVV----TDPATDGLMVPVTPA 2973
Query: 269 EGYLAKILVPE----------GTRDVP-LGTPLCIIVEKEADISAFADYRPTEVTDLKPQ 317
G +A + + E GT P +G P ++ + AD S ++ PT + P
Sbjct: 2974 NGSVAPVTLSEYPDVTVTPADGTVVSPTIGGP--VVPDPSADSSVVSN--PTTDGLIVPN 3029
Query: 318 VPPPTPPPVAAVPPTPQPLAPTPSAPCP---ATPA-GP-------KGRVFVSPLAKKLAV 366
P PV V PT PLAP A CP TPA GP G VF P A+ L V
Sbjct: 3030 --PLLAGPVVPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTTGGPVFPDPTAEGLVV 3087
Query: 367 EK-GIDLTQVKGTGPDGRITKKDID-SFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIP 424
+D V G ++ D + VP A P +V + P T +T +
Sbjct: 3088 SNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSVVPDFTADWTVVS 3147
Query: 425 IS 426
+S
Sbjct: 3148 VS 3149
Score = 40.8 bits (94), Expect = 0.004
Identities = 57/246 (23%), Positives = 88/246 (35%), Gaps = 29/246 (11%)
Query: 187 PTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGT-VQRWEKKVGEK 245
PT TPA T P SA P P ++P ++P T G+ V + V
Sbjct: 1401 PTGDPIVPVTPADTPGSPVTSADGPVVPVTPAGDPIVP-VTPADTPGSPVTSADGPVVPV 1459
Query: 246 LSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFAD 305
+ L + + +G + + P + +P+ T AD
Sbjct: 1460 TTPDGPLVPVSPPDGPVVPVTSADGPVVPV-TPADSPFIPVTT---------------AD 1503
Query: 306 YRPTEVTDLKPQVPPPTPPPVAAVPPTPQ--PLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
VT V P TP + VP TP P+ SA CP P V P
Sbjct: 1504 DPIVPVTPADSPVVPVTPADIPVVPVTPANGPVIHVTSADCPFVP--------VIPADGL 1555
Query: 364 LAVEKGIDLTQVKGTGPDGRITKKDIDSFVPS-KVAPAPAAVVPPTGPGMAPVPTGVFTD 422
+A++ D+ V + DG + D V S +A +P V P + PV
Sbjct: 1556 VALDSSTDVLVVPVSPTDGVLVPDLADDPVVSVTIADSPVIPVTPADSTVVPVTLADGPV 1615
Query: 423 IPISNI 428
+P++++
Sbjct: 1616 VPVTSV 1621
Score = 37.7 bits (86), Expect = 0.033
Identities = 36/123 (29%), Positives = 43/123 (34%), Gaps = 18/123 (14%)
Query: 311 VTDLKPQVPPPTP--PPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFV------SPLAK 362
VT V P TP PV +V P + P SA CP P P + V SP+
Sbjct: 1628 VTPANGPVAPVTPVDDPVVSVNPADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVP 1687
Query: 363 KLAVEKGIDLTQ---------VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMA 413
+ + L P +T D DS S V A VVP T
Sbjct: 1688 VTPADSPVVLVTSADSPVIPVTPADSPVVPVTSADTDS-PGSPVTSADGPVVPVTSADSL 1746
Query: 414 PVP 416
PVP
Sbjct: 1747 PVP 1749
Score = 37.0 bits (84), Expect = 0.057
Identities = 42/147 (28%), Positives = 56/147 (38%), Gaps = 8/147 (5%)
Query: 285 PLGTPLCIIVEKEAD-ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTP--QPLAPTPS 341
P +P+ + ++ I AD VT V P TPP VP TP P+ P
Sbjct: 2011 PTDSPVVPVTSADSPVIPVTADSPFVPVTPADSPVIPVTPPDDLVVPVTPIDCPVVPVTL 2070
Query: 342 APCPATPAGPKGRVF--VSPLAKKLAVEKGIDLTQVKGTGPDGRITK-KDIDSFVPSKVA 398
CP P V+P + D + T D I DS + S V
Sbjct: 2071 VDCPVVSVTPANSPVDPVTPADGPVVPVTPADSPVIPVTPADDLIVPVTPADSLIVS-VT 2129
Query: 399 PAPAAVVPPTGPGMAPVPTGVFTDIPI 425
PA + VVP T P +PV + D P+
Sbjct: 2130 PADSPVVPVT-PADSPVISVASADSPV 2155
Score = 36.6 bits (83), Expect = 0.074
Identities = 70/277 (25%), Positives = 91/277 (32%), Gaps = 70/277 (25%)
Query: 182 DSSAAP-TPQAAPAPTPAATASP--PTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRW 238
DS P TP P + A+ SP P A P S P ++P S + V
Sbjct: 374 DSPVVPVTPADGPVVSVASADSPFVPVTPADDPIVSVTPADSPVVPVTSADSPLIPVTTA 433
Query: 239 EKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEA 298
+ +V + GD + VP D P G+P+
Sbjct: 434 DGRVVPVTAAGDPI------------------------VPVTPADTP-GSPV-------- 460
Query: 299 DISAFADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVF 356
AD VT + P TPP PV V P+AP SA P P P F
Sbjct: 461 ---TSADGPVVPVTSADIPLVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTPADSPF 517
Query: 357 V----------------SPLAKKLAVEK-GIDLTQ--------VKGTGPDGRITKKDIDS 391
+ SP+ E I +T GP +T D
Sbjct: 518 IPVTTADDLIVPVTPADSPVLSVTPAESPAIPVTPADSPIVPVTPANGPVVPVTSAD-SP 576
Query: 392 FVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNI 428
FVP V PA VVP T P +PV D P+ ++
Sbjct: 577 FVP--VIPADGPVVPVT-PADSPVVPVTPADSPVLSV 610
Score = 36.6 bits (83), Expect = 0.074
Identities = 57/257 (22%), Positives = 87/257 (33%), Gaps = 12/257 (4%)
Query: 182 DSSAAPTPQAAPAPTPAATASPPT---PSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRW 238
D P A P TA PT A +P PP ++P S V
Sbjct: 1774 DGPVVPVTPADSPVVPVTTADDPTVPVTPADSPVVPVPPANGPIVPVTSADSPFVPVIPA 1833
Query: 239 EKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDV-PLGTPLCIIVEKE 297
+ V S L+ + + ++ ++ ++ + V P +P+ ++ +
Sbjct: 1834 DGLVVLDSSTDVLVVPVSPTDGILVPDLADDPVVSVTIADSPVIPVTPADSPVVLVTPAD 1893
Query: 298 ADISAFA--DYRPTEVTDLKPQVPPPTP--PPVAAVPPTPQPLAPTPSAPCPATPAGPKG 353
+ D VT V P TP PV V P P+ P SA P P
Sbjct: 1894 GPVVPVTSVDNPVVPVTPADNPVIPVTPVDDPVVPVTPADDPIVPVTSADSPIVSVTPAD 1953
Query: 354 R-VF-VSPLAKKLAVEKGIDLTQVKGTGPDGRITK--KDIDSFVPSKVAPAPAAVVPPTG 409
VF V+P + D V T D + +P A +PA V PT
Sbjct: 1954 SPVFPVTPADSPVIPVASADSPLVPVTPADMVVVPVIPADGPVIPVTPAESPAIPVTPTD 2013
Query: 410 PGMAPVPTGVFTDIPIS 426
+ PV + IP++
Sbjct: 2014 SPVVPVTSADSPVIPVT 2030
Score = 36.6 bits (83), Expect = 0.074
Identities = 67/308 (21%), Positives = 105/308 (34%), Gaps = 61/308 (19%)
Query: 156 DVPIGAIICITVG-KPEDIEAFKNYTLDSSAAPTPQ----AAPAPTPAATASPPT----- 205
DVP+ C V P+ + +D P P AP P P
Sbjct: 3466 DVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPEPPDEVPVVPDPITDSL 3525
Query: 206 ----PSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKAT 261
P P +S P +++P +SP+ + V + +++ +L + D
Sbjct: 3526 VVSDPMTDGPVASDPSIDGIVVPVVSPSGLL---------VLDSVADVSILPDTSADVPV 3576
Query: 262 IGFEVQEEGYLAKILVPEGTRDVPLGTPLC-------------IIVEKEADISAFADYRP 308
+ + +VP+ D P+ L ++V AD+
Sbjct: 3577 TPVTLADGS-----VVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPT 3631
Query: 309 TEVTD-LK--PQVPPPTPP-PVAAVPPTPQPLAPTPSAP---CPATPAGPKGRVFVSPLA 361
T+ D +K P VP P P PV V T P+ SA P TP G V+P
Sbjct: 3632 TDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTP-GDDSVALVTPTD 3690
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDI------------DSFVPSKVAPAPAAVVPPTG 409
+ + D V DG + + D+ VP+ VA P A+ P T
Sbjct: 3691 NLVVPDLTTDGPVVPDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTD 3750
Query: 410 PGMAPVPT 417
+ P P+
Sbjct: 3751 CPLVPEPS 3758
Score = 36.2 bits (82), Expect = 0.097
Identities = 35/117 (29%), Positives = 47/117 (40%), Gaps = 11/117 (9%)
Query: 316 PQVP-PPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQ 374
P VP P PV VPP P+ P SA P P V P + ++ D+
Sbjct: 1796 PTVPVTPADSPVVPVPPANGPIVPVTSADSPFVP--------VIPADGLVVLDSSTDVLV 1847
Query: 375 VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRV 431
V + DG + D V S V A + V+P T P +PV D P+ + V
Sbjct: 1848 VPVSPTDGILVPDLADDPVVS-VTIADSPVIPVT-PADSPVVLVTPADGPVVPVTSV 1902
Score = 36.2 bits (82), Expect = 0.097
Identities = 72/286 (25%), Positives = 97/286 (33%), Gaps = 33/286 (11%)
Query: 160 GAIICITVGKP------EDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS 213
G ++ T+G P D N T D P P A P PT AP
Sbjct: 2995 GTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIVPNPLLAGPVVPVT----PTDGPLAPVI 3050
Query: 214 SYPPHMQVLLPALSPTM----TMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEE 269
+ PA P + T G V G +S + + T+ +T G
Sbjct: 3051 LADCPDVTVTPADGPVVCAFTTGGPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATP 3110
Query: 270 GYLAKI-LVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPP--PV 326
A + ++P DV L +V AD+ V+ V P P PV
Sbjct: 3111 ADCADVPVIPADCPDV-----LVNLVNDSVVPDFTADWTVVSVSPPDDLVAPDPPDEVPV 3165
Query: 327 AAVPPTPQPLAP---TPSAPCPATPAG-PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDG 382
VP T P+ P T TPAG P VF++ D V DG
Sbjct: 3166 VLVPITDGPVVPDLTTDGLVVSVTPAGAPVVPVFLTDCPDVTVTP--ADSPVVPDPSSDG 3223
Query: 383 RITKKDIDSFVPSKVAPAPAAVVP--PTGPGMAPVPTGVFTDIPIS 426
+ +D V PA +VVP P + P PT TD P++
Sbjct: 3224 PVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPT---TDGPVA 3266
Score = 35.8 bits (81), Expect = 0.13
Identities = 40/128 (31%), Positives = 48/128 (37%), Gaps = 19/128 (14%)
Query: 304 ADYRPTEVTDLKPQVPPPTPP-----PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVF-V 357
AD VT V P TP PVA+ P+ P S P TPA +F V
Sbjct: 124 ADNPVVPVTSANGPVIPVTPADSPVFPVASADGPVVPVTPADSPVFPVTPA--DSPLFPV 181
Query: 358 SPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
+P L D + T DG + V PA VVP T P +PV T
Sbjct: 182 TPADSPLFPVTPADSAAIPVTPADGPVV----------HVTPANGTVVPVT-PADSPVVT 230
Query: 418 GVFTDIPI 425
TD P+
Sbjct: 231 VASTDSPV 238
Score = 35.4 bits (80), Expect = 0.16
Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 5/106 (4%)
Query: 325 PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVS--PLAKKLAVEKGIDLTQVKGTGPDG 382
PV V P P+ P P A P P FV P + ++ D+ V + DG
Sbjct: 1167 PVVPVTPADSPVIPVPPANGPVVPVSSADSPFVPVIPADGLVVLDSSTDVLVVPVSPTDG 1226
Query: 383 RITKKDI--DSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPIS 426
I D+ D V +A +P V P + PV + +P++
Sbjct: 1227 -ILVPDLADDPVVSVTIADSPVIPVTPADSPVVPVTSADSPVVPVT 1271
Score = 34.7 bits (78), Expect = 0.28
Identities = 29/112 (25%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 321 PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVS--PLAKKLAVEKGIDLTQVKGT 378
P PV V P P+ P P A P G FV P + ++ D+ V +
Sbjct: 2310 PADSPVVPVTPANIPVVPVPPANGSVVPVTSAGSPFVPIIPADGLVVLDSSTDVLVVLVS 2369
Query: 379 GPDGRITKKDI--DSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNI 428
DG I D+ D V + +P V PT + PV +P++++
Sbjct: 2370 PTDG-IPVPDLADDPVVSVTTSDSPVIPVTPTDSPVVPVAPADGPVVPVTSV 2420
Score = 33.9 bits (76), Expect = 0.48
Identities = 37/117 (31%), Positives = 43/117 (36%), Gaps = 21/117 (17%)
Query: 311 VTDLKPQVPPPTPP--PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEK 368
VT V P TP PV V P P+ P P A P P P SP+A
Sbjct: 2188 VTPADSPVVPVTPADDPVVPVTPADSPIVPVPPASDPVVPVTPADTP-GSPVA------- 2239
Query: 369 GIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPI 425
GP +T D VP V P + VVP T P +PV D P+
Sbjct: 2240 -------SADGPVVPVTSAD-SPLVP--VTPGDSPVVPVT-PADSPVFPVTSADGPV 2285
Score = 33.9 bits (76), Expect = 0.48
Identities = 30/108 (27%), Positives = 37/108 (34%), Gaps = 3/108 (2%)
Query: 312 TDLKPQVP-PPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGR--VFVSPLAKKLAVEK 368
T P +P PT PV V P P+ P S P P P + V+P +
Sbjct: 2389 TSDSPVIPVTPTDSPVVPVAPADGPVVPVTSVDSPVVPVTPADSPVIPVTPADSLVVPAT 2448
Query: 369 GIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVP 416
D V T DG + V A + VVP T VP
Sbjct: 2449 PADDPVVSVTPADGPVVPVTTADIPVISVTSADSPVVPVTPADGLVVP 2496
Score = 33.9 bits (76), Expect = 0.48
Identities = 63/261 (24%), Positives = 89/261 (34%), Gaps = 32/261 (12%)
Query: 180 TLDSSAAP-TPQAAPA--PTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQ 236
++DS P TP +P TPA + P A P S P ++P + + + +V
Sbjct: 2419 SVDSPVVPVTPADSPVIPVTPADSLVVPATPADDPVVSVTPADGPVVPVTTADIPVISVT 2478
Query: 237 RWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPL------GTPL 290
+ V L+ + + + ++VP D PL +P+
Sbjct: 2479 SADSPVVPVTPADGLVVPVTSADS--------------VVVPATPADCPLVPVDPADSPI 2524
Query: 291 CIIVEKEADI-SAFADYRPT-EVTDLKPQVPPPTPPPVAAVPPTP-----QPLAPTPSAP 343
+ + + S +D P VT V P TP V VP TP P+ P S
Sbjct: 2525 VLFTPYDNPVVSVTSDDSPVFPVTPADSSVVPVTPAGVPVVPVTPGDGPVVPVTPADSLV 2584
Query: 344 CPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAA 403
P T A + V DL G + DS V V PA
Sbjct: 2585 VPVTSADSPVFPVTPADSPVFPVSPADDLVVPVTPGDSPVVPVSPADSPV-VLVTPADGP 2643
Query: 404 VVPPTGPGMAPVPTGVFTDIP 424
VVP T P PV D P
Sbjct: 2644 VVPVT-PANGPVVPVTSADSP 2663
Score = 33.5 bits (75), Expect = 0.63
Identities = 29/113 (25%), Positives = 38/113 (33%), Gaps = 8/113 (7%)
Query: 321 PTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFV------SPLAKKLAVEKGIDLTQ 374
P PV V P P+ SA P P P V V P+ E +
Sbjct: 2130 PADSPVVPVTPADSPVISVASADSPVVPVTPADTVVVPVTPADGPVIPVTPAESPA-IPV 2188
Query: 375 VKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISN 427
P +T D D VP A +P VPP + PV P+++
Sbjct: 2189 TPADSPVVPVTPAD-DPVVPVTPADSPIVPVPPASDPVVPVTPADTPGSPVAS 2240
Score = 33.1 bits (74), Expect = 0.82
Identities = 43/156 (27%), Positives = 57/156 (36%), Gaps = 22/156 (14%)
Query: 304 ADYRPTEVTDLKPQVPPPTPPPVAAVPPTP--QPLAP-TP---------SAPCPATPAGP 351
AD VT V P TP VP TP P+ P TP SA P P P
Sbjct: 1651 ADGSVVPVTSADCPVVPVTPADGLVVPVTPADSPIVPVTPADSPVVLVTSADSPVIPVTP 1710
Query: 352 KGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPT--- 408
SP+ + + + V T DG + +P V PA VVP T
Sbjct: 1711 AD----SPVVPVTSADTDSPGSPV--TSADGPVVPVTSADSLPVPVTPADGPVVPVTSAD 1764
Query: 409 GPGMAPVPTGVFTDIPISNIRRVIAQRLMQSKQTIP 444
GP +APV + +P++ + T+P
Sbjct: 1765 GP-VAPVSSADGPVVPVTPADSPVVPVTTADDPTVP 1799
Score = 33.1 bits (74), Expect = 0.82
Identities = 32/127 (25%), Positives = 45/127 (35%), Gaps = 15/127 (11%)
Query: 316 PQVP-PPTPPPVAAVPPTPQPLAPTPSAPCPATP--AGPKGRVFVSPLAKKLAVEKGIDL 372
P VP PP PV V P P +P SA P P + V V+P + D
Sbjct: 2214 PIVPVPPASDPVVPVTPADTPGSPVASADGPVVPVTSADSPLVPVTPGDSPVVPVTPADS 2273
Query: 373 TQVKGTGPDGRITKKDI------------DSFVPSKVAPAPAAVVPPTGPGMAPVPTGVF 420
T DG + + D P A +P V P + PVP
Sbjct: 2274 PVFPVTSADGPVFPVTLADDPVFPVTPADDPIFPVSPADSPVVPVTPANIPVVPVPPANG 2333
Query: 421 TDIPISN 427
+ +P+++
Sbjct: 2334 SVVPVTS 2340
Score = 32.3 bits (72), Expect = 1.4
Identities = 34/147 (23%), Positives = 45/147 (30%), Gaps = 32/147 (21%)
Query: 285 PLGTPLCIIVEKEAD------ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP 338
P +P+ + + D SA P D P P PV V P+AP
Sbjct: 1710 PADSPVVPVTSADTDSPGSPVTSADGPVVPVTSADSLPVPVTPADGPVVPVTSADGPVAP 1769
Query: 339 TPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVA 398
SA P P P P +T D D VP A
Sbjct: 1770 VSSADGPVVPVTP-------------------------ADSPVVPVTTAD-DPTVPVTPA 1803
Query: 399 PAPAAVVPPTGPGMAPVPTGVFTDIPI 425
+P VPP + PV + +P+
Sbjct: 1804 DSPVVPVPPANGPIVPVTSADSPFVPV 1830
Score = 31.6 bits (70), Expect = 2.4
Identities = 60/255 (23%), Positives = 91/255 (35%), Gaps = 26/255 (10%)
Query: 187 PTPQAAPAPTPAATASP------PTPSAQAPGSSYPPHMQVLL---PALSPTMTMGTVQR 237
P PA +P + +P P SA +P P ++ PA SP + V +
Sbjct: 957 PIVPVTPADSPVVSVTPADGPVVPVASADSPFVPVTPADDPIVSVTPAESPAIP---VTQ 1013
Query: 238 WEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKE 297
+ V S ++ + T I V G + P T P+ + +V
Sbjct: 1014 ADSPVVPVTSADRPVSPVTTADGRI-VPVTAAGDPIVPVTPADTPGSPVTSADGPVVPVT 1072
Query: 298 ADISAFADYRPTE-----VTDLKPQVPPPTPP--PVAAVPPTPQPLAPTPSAPCPATPAG 350
+ S F P + VT V P + PV V P+AP SA P P
Sbjct: 1073 SADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSSADGPVVPVT 1132
Query: 351 PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGP 410
P F+ P+ A + + +T P +T D VP A +P VPP
Sbjct: 1133 PADSPFI-PVT--TADDPIVPVT--PADSPVLSVTLAD-SPVVPVTPADSPVIPVPPANG 1186
Query: 411 GMAPVPTGVFTDIPI 425
+ PV + +P+
Sbjct: 1187 PVVPVSSADSPFVPV 1201
Score = 30.8 bits (68), Expect = 4.1
Identities = 59/274 (21%), Positives = 90/274 (32%), Gaps = 51/274 (18%)
Query: 170 PEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPT 229
P D DS A P A P A P + S + P + PA P
Sbjct: 602 PADSPVLSVTLADSPAVPVTPADSPVVPVTPADGPVVPVASADSPFVP----VTPADDPI 657
Query: 230 MTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKI------LVPEGTRD 283
+++ + V + ++ ++ D+ I + G + + +VP D
Sbjct: 658 VSVTPAESPAIPVTQ--ADSPVVPVTSADRPVIPVTTAD-GRIVPVTAAGDPIVPVTPAD 714
Query: 284 VPLGTPLC-----IIVEKEADISAFADYRPTE-----VTDLKPQVPPPTPP--PVAAVPP 331
P G+P+ ++ AD S F P + VT V P + PV V
Sbjct: 715 TP-GSPVTSADGPVVPVTSAD-SPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTS 772
Query: 332 TPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDS 391
P+AP SA P P +T GP +T D
Sbjct: 773 ADGPVAPVSSADGPVVP-----------------------VTPADTNGPAVPVTSAD-SP 808
Query: 392 FVPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPI 425
FVP A +P V P + PV + +P+
Sbjct: 809 FVPVIPADSPVVPVTPADDPIVPVTPADSSFVPV 842
Score = 30.8 bits (68), Expect = 4.1
Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 14/134 (10%)
Query: 304 ADYRPTEVTDLKPQVPPPTPP--PVAAVPPTPQPLAPTPSAPCPATPA----GPKGRVFV 357
AD VT P TPP PV V P+AP SA P P GP V
Sbjct: 1064 ADGPVVPVTSADSPFVPVTPPDGPVVPVTSADGPVAPVSSADGPVVPVTSADGPVAPVSS 1123
Query: 358 S--PLAKKLAVEKG-IDLTQVKGTGPDGRITKKDIDSFVPS-KVAPAPAAVVPPTGPGMA 413
+ P+ + I +T T D + DS V S +A +P V P +
Sbjct: 1124 ADGPVVPVTPADSPFIPVT----TADDPIVPVTPADSPVLSVTLADSPVVPVTPADSPVI 1179
Query: 414 PVPTGVFTDIPISN 427
PVP +P+S+
Sbjct: 1180 PVPPANGPVVPVSS 1193
Score = 30.8 bits (68), Expect = 4.1
Identities = 34/113 (30%), Positives = 41/113 (36%), Gaps = 16/113 (14%)
Query: 304 ADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
AD VT + V P TP +P T P S PATPA V V+P
Sbjct: 2410 ADGPVVPVTSVDSPVVPVTPADSPVIPVT-----PADSLVVPATPADDP-VVSVTPADGP 2463
Query: 364 LAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVP 416
+ D+ + T D + VP V PA VVP T VP
Sbjct: 2464 VVPVTTADIPVISVTSADSPV--------VP--VTPADGLVVPVTSADSVVVP 2506
Score = 30.4 bits (67), Expect = 5.3
Identities = 28/108 (25%), Positives = 34/108 (31%), Gaps = 6/108 (5%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVE 367
P TD P PV V P P A CP P + VS + V
Sbjct: 3257 PDPTTDGPVAPDPSVDGPVVPVTPADAPTVSVTLADCPDVTVTPPDGLVVSDSKRGGPVV 3316
Query: 368 KGID-----LTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGP 410
G+ +T D +T D + VP A P V P P
Sbjct: 3317 TGLSTNDPVITATPADFSDVTVTPADFED-VPVTPANCPDVPVNPESP 3363
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 47.0 bits (110), Expect = 5e-05
Identities = 75/299 (25%), Positives = 103/299 (34%), Gaps = 71/299 (23%)
Query: 145 MAKILVAEGTRDVPIGAIICITVGKP-EDIEAFKNYTL---DSSAAPTPQAAPAPTPAAT 200
+A + EGT A++ V P EDI +L D +AA A PA T
Sbjct: 860 IAAVPAPEGT------AVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVT 913
Query: 201 ASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKA 260
S P +A S P + PA++ +T E A
Sbjct: 914 VSVPEGTAAVAAVSSP---EETAPAVAAAITQ-----------------------EGMSA 947
Query: 261 TIGFEVQEEGYLAKILVPE--GTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQV 318
GF + + + E GT + P+ + +E D +A P E V
Sbjct: 948 VAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAV 1007
Query: 319 PPPTPP---------------PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKK 363
P P P P AAVPP +P +P + P P P P V P ++
Sbjct: 1008 PTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAV---PTPEE 1064
Query: 364 LAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAP-APAAVVP----PTGPGMAPVPT 417
T + T P + VP+ P +PAA VP PT P A VPT
Sbjct: 1065 PTSPAAAVPTPEEPTSP---------AAAVPTPEEPTSPAAAVPTPEEPTSPA-AAVPT 1113
Score = 44.7 bits (104), Expect = 3e-04
Identities = 69/261 (26%), Positives = 94/261 (36%), Gaps = 54/261 (20%)
Query: 183 SSAAPTPQ-----AAPAPTPAATASP----PTPSAQA--------PGSSYPPHMQVLLPA 225
++A PTP+ AA PTP A P PTP A P S P V PA
Sbjct: 1121 AAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180
Query: 226 LSPTMT--MGTVQRWEKKVGEKLSEGDLLAEIE---TDKATIGFEVQEEGYLAKILVPEG 280
S + + T++ + ++A +E + A++ + A + PE
Sbjct: 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240
Query: 281 TRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPP--PVAAV-----PPTP 333
P + +E SA A P E++ VP P P P AAV P +P
Sbjct: 1241 ----PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASP 1296
Query: 334 QPLAPTP--------SAPCPATPAGPKGRV----FVSPLAKK-LAVEKGIDLTQVKGTG- 379
PTP S P P PA P V VSP+ L V D + G
Sbjct: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGT 1356
Query: 380 -------PDGRITKKDIDSFV 393
G K+D+DS V
Sbjct: 1357 PVLEEASSTGMWIKEDLDSLV 1377
Score = 43.1 bits (100), Expect = 8e-04
Identities = 66/293 (22%), Positives = 93/293 (31%), Gaps = 81/293 (27%)
Query: 152 EGTRDVPIGAIICITVGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASP----PTPS 207
+GT + P+ + + D A + T + A+P AA PTP SP PTP
Sbjct: 968 DGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASP---AAAVPTPEEPTSPAAAVPTPE 1024
Query: 208 AQ-APGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEV 266
+P ++ PP + PA +
Sbjct: 1025 EPTSPAAAVPPPEEPTSPAAA--------------------------------------- 1045
Query: 267 QEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPP-- 324
VP T + P + +E A A P E T VP P P
Sbjct: 1046 ----------VP--TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Query: 325 PVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRI 384
P AAVP +P +P + P P PA P V T + P +
Sbjct: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAV----------------PTPEEPASPAAAV 1137
Query: 385 TKKDIDSF----VPSKVAPAPAAVVPPTGPGMAPVPTGVFTDIPISNIRRVIA 433
+ +F VP+ A AAV PT A V T ++ V+A
Sbjct: 1138 PTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190
>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
Length = 1711
Score = 47.0 bits (110), Expect = 5e-05
Identities = 67/243 (27%), Positives = 90/243 (37%), Gaps = 53/243 (21%)
Query: 185 AAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGE 244
A P + PAP P + P + P S PP V PAL+P V
Sbjct: 220 AFQVPLSVPAPVPHSGLVPVQVATSVPAPS-PPLAPV--PALAPA---------PPSVPT 267
Query: 245 KLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
+S+ + L+ A +LVP P G P+ + A +S
Sbjct: 268 LISDSNPLS-----------------VSASVLVPVPASAPPSG-PVPLSAPAPAPLSVPV 309
Query: 305 DYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKL 364
P + ++ VPP P V A PTP LAP P++ PA PA P P+
Sbjct: 310 SAPPLAL--IQAPVPPSAPTLVLAPVPTP-VLAPMPASTPPAAPAPPS-----VPMP--- 358
Query: 365 AVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKV-APAPAAV-VPPTGPGMAPVPTGVFTD 422
T +GP T I +F P+ V AP PA + P P A P + T
Sbjct: 359 --------TPTPSSGPPS--TPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408
Query: 423 IPI 425
PI
Sbjct: 409 API 411
Score = 43.9 bits (102), Expect = 5e-04
Identities = 56/182 (30%), Positives = 73/182 (40%), Gaps = 29/182 (15%)
Query: 260 ATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRPTEVTDLKPQVP 319
AT+G V EG L + T PL P+C A SA + + + VP
Sbjct: 177 ATLGTGVPVEGTLPLVT----TNFSPLPAPIC----PPAPGSASVPHSVPDAFQVPLSVP 228
Query: 320 PPTPP----PV---AAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKGIDL 372
P P PV +VP PLAP P A PA P+ P +PL+ +V L
Sbjct: 229 APVPHSGLVPVQVATSVPAPSPPLAPVP-ALAPAPPSVPTLISDSNPLSVSASV-----L 282
Query: 373 TQVKGTGPDGRITKKDIDSFVPSKV---APAPAAV---VPPTGPGM--APVPTGVFTDIP 424
V + P + P V AP A + VPP+ P + APVPT V +P
Sbjct: 283 VPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMP 342
Query: 425 IS 426
S
Sbjct: 343 AS 344
Score = 42.4 bits (98), Expect = 0.001
Identities = 62/266 (23%), Positives = 93/266 (34%), Gaps = 46/266 (17%)
Query: 180 TLDSSAAPTPQAAPAPT---PAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQ 236
TL + PTP AP P PAA A P P SS PP L+PA +PT
Sbjct: 327 TLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTP 386
Query: 237 RWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEK 296
A I T + L+++ P PL
Sbjct: 387 APIFTPAPTPMPAATPAAIPTSA-----PIPASFSLSRVCFPAAQAPAMQKVPL------ 435
Query: 297 EADISAFADYRP-TEVTDLKP--QVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKG 353
++P T +T +P +PPP+ +V P L + + P P+ +
Sbjct: 436 --------SFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTTLGVSSTLTLPVLPSYLQD 487
Query: 354 R----VFVSP----------LAKKLAVEK---GIDLTQVKGTGPDGRITKKDIDSFVPSK 396
R V SP +A+ L + +++ ++ T P G T + VP
Sbjct: 488 RCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGP 547
Query: 397 VAP----APAAVVPPTGPGMAPVPTG 418
+A +A V PT + P P+G
Sbjct: 548 LADTSLVTASAKVLPTPQPLLPAPSG 573
Score = 38.5 bits (88), Expect = 0.019
Identities = 64/252 (25%), Positives = 86/252 (34%), Gaps = 26/252 (10%)
Query: 183 SSAAPTPQAAPAPTPAATA--SPPTPSAQAPG-SSYPPHMQVLLPALSPTMTMGTVQRWE 239
S AP P + P AT+ +P P A P + PP + L+ +P +V
Sbjct: 226 SVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPV 285
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
L A A + V LA I P VP P ++
Sbjct: 286 PASAPPSGPVPLSAPAP---APLSVPVSAPP-LALIQAP-----VPPSAPTLVLAPVPTP 336
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTP---QPLAPTP-SAPCPA---TPA-GP 351
+ A P VP PTP P + P TP APTP AP PA TPA P
Sbjct: 337 VLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTP 396
Query: 352 KGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKV--APAPAAVVPPTG 409
+ + + L++V +K SF P V P +PP
Sbjct: 397 MPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGTVLTPSQPLVYIPPPS 456
Query: 410 PG----MAPVPT 417
G +A +PT
Sbjct: 457 CGQPLSVATLPT 468
Score = 35.0 bits (79), Expect = 0.22
Identities = 70/292 (23%), Positives = 104/292 (35%), Gaps = 64/292 (21%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASP-----------PT---------------PSAQAPGS 213
TL + APTP AP P P T +P PT P+AQAP
Sbjct: 371 TLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAM 430
Query: 214 SYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQ----EE 269
P L+P+ + + G+ LS L + +T+ V ++
Sbjct: 431 QKVPLSFQPGTVLTPSQPLVYIP--PPSCGQPLSVATLPTTLGVS-STLTLPVLPSYLQD 487
Query: 270 GYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYR-----PTEVTDLKPQVPPPTPP 324
L +L R P + + ++ + + R P+ T +P P P
Sbjct: 488 RCLPGVLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQP-APDGVPG 546
Query: 325 PVA---------AVPPTPQPLAPTPSA----PCPA-TPAGPKGR-----VFVSPLAKKLA 365
P+A V PTPQPL P PS P PA P+G + + V SPL
Sbjct: 547 PLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSGTEQQTEGTSVTFSPLKSPPQ 606
Query: 366 VEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPT 417
+E+ + + P+ D+ S + P P P P + PV T
Sbjct: 607 LEREM------ASPPECSEMPLDLSSKSNRQKLPLPNQRKTPPMPVLTPVHT 652
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 47.0 bits (110), Expect = 5e-05
Identities = 73/242 (30%), Positives = 86/242 (35%), Gaps = 42/242 (17%)
Query: 185 AAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGE 244
A P P+ AP TPAAT PP+P ++ PP PA +P G + K
Sbjct: 1141 ATPPPKGAPT-TPAAT--PPSPKGGL--ATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195
Query: 245 KLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFA 304
T AT +G LA P+G P TP A
Sbjct: 1196 T-----------TPAAT---PPSPKGGLATPS-PKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 305 DYRPTEVTDLK---PQVPPP--TPPPVAAVPPTPQPLAPTP---SAPCPA--TPAGPKGR 354
P P PPP P P AA PP+ + TP AP PA TP PKG
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 355 VFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
SP KG T T P + K P K AP P AV PP+ G
Sbjct: 1301 PATSP-------PKGAP-TPPAATPP----SPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 415 VP 416
+P
Sbjct: 1349 LP 1350
Score = 46.2 bits (108), Expect = 9e-05
Identities = 67/251 (26%), Positives = 84/251 (33%), Gaps = 65/251 (25%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T APTP AA P+P + P+P G+ PP + P SP T
Sbjct: 979 TPSPKGAPTPPAATPPSPKGGPATPSPK----GAPTPPAVTPPSPKGSPAAT-------- 1026
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
+G P T P G+P + K A
Sbjct: 1027 -----PFPKG------------------------ASTPPAATPPSPKGSPAATPLPKGAP 1057
Query: 300 ISAFADYRPTEVTDLKPQVP-PPTPPPVAAVPPTPQ--PLAPTP-SAPCP--ATPAGPKG 353
+ A + P + PTPP AA PP+P+ P P+P AP P ATP PKG
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPP--AATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 354 RVFVSPLAKKLAVEKGIDLT-QVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPG- 411
+ P KG T P G + P K AP A PP+ G
Sbjct: 1116 GLATPP-------HKGAPTTPAATPPSPKGGLATP------PPKGAPTTPAATPPSPKGG 1162
Query: 412 -MAPVPTGVFT 421
P P G T
Sbjct: 1163 LATPPPKGAPT 1173
Score = 45.1 bits (105), Expect = 2e-04
Identities = 66/253 (26%), Positives = 90/253 (35%), Gaps = 21/253 (8%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
T ++ P+P+ +PA TP +P TP+A P P L A PT T +
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA--PTPPAATPPSPK 1091
Query: 240 KKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEAD 299
+G + T + G + + P T P G L K A
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKG-GLATPPHKGAPTTPAATPPSPKG-GLATPPPKGAP 1149
Query: 300 ISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPS---APC--PATPAGPKGR 354
+ A P+ L P P AA PP+P+ TPS AP ATP PKG
Sbjct: 1150 TTPAAT-PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 355 VF--------VSPLAKKLAVEKGIDLTQVKGTGPDGRIT---KKDIDSFVPSKVAPAPAA 403
+ +P A + + G+ KG T K + P K AP P A
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268
Query: 404 VVPPTGPGMAPVP 416
PP+ G P
Sbjct: 1269 ATPPSLKGGLATP 1281
Score = 44.3 bits (103), Expect = 4e-04
Identities = 64/250 (25%), Positives = 85/250 (34%), Gaps = 21/250 (8%)
Query: 185 AAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGE 244
A P+P+ AP P PA T PP+P + +P PA +P G+ G
Sbjct: 1001 ATPSPKGAPTP-PAVT--PPSPKGSPAATPFPKGAST-PPAATPPSPKGSPAATPLPKGA 1056
Query: 245 KLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEG--TRDVPLGTPLCIIVEKEADISA 302
+ L + AT + A P+G P G P+ +
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116
Query: 303 FADYRPTEVTDLKPQVPPPTP------PPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVF 356
A P + P PP+P PP P TP P+P P PKG
Sbjct: 1117 LAT-PPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP--PKGAP- 1172
Query: 357 VSPLAKKLAVEKGIDLTQVKG--TGPDGRITKKDIDSFVPS-KVAPAPAAVVPPTGPG-- 411
+P A + + G+ KG T P PS K AP A PP+ G
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232
Query: 412 MAPVPTGVFT 421
P P G T
Sbjct: 1233 ATPSPKGAPT 1242
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/112 (36%), Positives = 46/112 (41%), Gaps = 22/112 (19%)
Query: 319 PPPTPPPVAAVPPTPQ--PLAPTPS-APCP--ATPAGPKGRVFVSPLAKKLAVEKGIDLT 373
P P P AA PP+P+ P P+P AP P ATP PKG +P K
Sbjct: 936 PKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP-ATPSPKGAPTPPAATPP 994
Query: 374 QVKGTGPDGRITKKDIDSFVPS-KVAPAPAAVVPPT---GPGMAPVPTGVFT 421
KG GP PS K AP P AV PP+ P P P G T
Sbjct: 995 SPKG-GP-----------ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Score = 43.5 bits (101), Expect = 6e-04
Identities = 76/263 (28%), Positives = 95/263 (36%), Gaps = 49/263 (18%)
Query: 185 AAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQV-LLPALSPTMTMGTVQRWEKKVG 243
A P+P+ AP P PAAT PP+P G + PPH PA +P G + K
Sbjct: 1095 ATPSPKGAPMP-PAAT--PPSPKG---GLATPPHKGAPTTPAATPPSPKGGLATPPPKGA 1148
Query: 244 EKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTP------LCIIVEKE 297
T AT +G LA P+G P TP L K
Sbjct: 1149 PT-----------TPAAT---PPSPKGGLATP-PPKGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 298 ADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPP-------TPQP--LAPTPSAPCPATP 348
A + A P+ L P P AA PP TP P TP+A P+
Sbjct: 1194 APTTPAAT-PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 349 AG-----PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRIT---KKDIDSFVPSKVAPA 400
G PKG P A +++ G+ KG +T K + P K AP
Sbjct: 1253 GGPATPPPKGAP-TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 401 PAAVVPPTGPGM--APVPTGVFT 421
P A PP+ G P P G T
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPT 1334
Score = 43.1 bits (100), Expect = 8e-04
Identities = 71/251 (28%), Positives = 92/251 (36%), Gaps = 37/251 (14%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWE 239
TL + P+P+ PAP AT+S P + P P + ++P+ SP T
Sbjct: 1466 TLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS-SPKEVPATPS--- 1521
Query: 240 KKVGEKLSEGDLLAEIET--DKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKE 297
S D +A T K T +E ++ P T P TP I KE
Sbjct: 1522 -------SRRDPIAPTATLLSKKTPATLAPKEA----LIPPAMTVPSPKKTP-AIPTPKE 1569
Query: 298 ADI---SAFADYRPTEVTDLKPQVPPP----TPPPVAAVPP--TPQPLAPTPSAP--CPA 346
A S A P P P PP V + P P P A TP +P PA
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629
Query: 347 TPAGPKGRVF---VSPLAKKLAVEKGIDLTQVKGT----GPDGRITKKDIDSFVPSKVAP 399
TPA PKG V+P + K + +T G G KK + VAP
Sbjct: 1630 TPA-PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 400 APAAVVPPTGP 410
AP + T P
Sbjct: 1689 APESTPIITAP 1699
Score = 40.0 bits (92), Expect = 0.007
Identities = 63/261 (24%), Positives = 97/261 (37%), Gaps = 34/261 (13%)
Query: 180 TLDSSAAPTPQAAPA-PTPAATASPP--TPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQ 236
T ++ P+P+ PA P P +PP TP + G + PPH PA+ +T + +
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV---VTPPSPK 1298
Query: 237 RWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILV---PEGTRDVPLGTPLCII 293
K + A + K + G + + P+GT +P TP
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP---- 1354
Query: 294 VEKEADISAFADYRPTEVTDLK-----PQVPPPTPPPVAAVP-----PTPQPLAPTPSAP 343
K + + PT P + PP+P A+P PT + P
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 344 CPATPAGPKGRVFVS------PLAKKLAVEKGIDLTQVKGTGPDGRITKKD--IDSFVP- 394
PATP +G S P ++++K + KG GP +K D + + P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPATPSSKGDPTLPAVTPP 1473
Query: 395 -SKVAPAPAAVVPPTGPGMAP 414
K PAP V + P AP
Sbjct: 1474 SPKEPPAPKQVATSSSPKKAP 1494
Score = 40.0 bits (92), Expect = 0.007
Identities = 57/243 (23%), Positives = 83/243 (34%), Gaps = 28/243 (11%)
Query: 180 TLDSSAAPTPQAAPAPTP-AATASPPTPSAQAPGSSYPPHMQ--VLLPALSPTMTMGTVQ 236
T APTP AA P+P + +PP A P + PP + LPA +P+ G
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 237 RWEKK-----VGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLC 291
K+ +G + K + + ++P + P TP
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP-ATP-- 1419
Query: 292 IIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTP----QPLAPTPSAPCPAT 347
+ + A + D P VT + + P T P P TP P P + P P
Sbjct: 1420 -VTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG-PATPSSKGDPTLPAVTPPSPKE 1477
Query: 348 PAGPKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPP 407
P PK +V S KK P G T + P +V P++ P
Sbjct: 1478 PPAPK-QVATSSSPKKAPAT----------PAPMGAPTLPAVIPSSPKEVPATPSSRRDP 1526
Query: 408 TGP 410
P
Sbjct: 1527 IAP 1529
Score = 39.3 bits (90), Expect = 0.011
Identities = 65/267 (24%), Positives = 94/267 (35%), Gaps = 40/267 (14%)
Query: 186 APTPQAAPAPTPAATASPP----TPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKK 241
AP+PQ AP +P PS P + PP + + +S T + V K+
Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKV-DGISHTSALAPVASSPKE 769
Query: 242 VGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTR----------DVPLGTPLC 291
+ S A + K T+ + L + P+ R D P+G
Sbjct: 770 CPTEDSGASATA---SSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826
Query: 292 IIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAG- 350
+ EA +F K P T P PP+P+ APTPSA P +P G
Sbjct: 827 PVSPVEA---SFLPENSLSFQGSKDS-PATTHSPT---PPSPKG-APTPSAVTPLSPKGV 878
Query: 351 -------PKGRVFVSPLAKK----LAVEKGIDLTQVKGTGPDGRIT--KKDIDSFVPSKV 397
P V P K+ A ++ L+ + R T K I + K
Sbjct: 879 TLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKG 938
Query: 398 APAPAAVVPPTGPGMAPVPTGVFTDIP 424
AP P A PP+ G P+ + P
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTP 965
>gi|223278403 glutamate receptor, ionotropic, delta 2 (Grid2)
interacting protein [Homo sapiens]
Length = 1211
Score = 46.6 bits (109), Expect = 7e-05
Identities = 55/200 (27%), Positives = 76/200 (38%), Gaps = 35/200 (17%)
Query: 167 VGKPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGS-------SYPPH- 218
+ P E+ +LDSS AP+PQ P P P SPP+P P S S+P
Sbjct: 619 LASPSSSESHPYASLDSSRAPSPQ--PGPGPICPDSPPSPDPTRPPSRRKLFTFSHPVRS 676
Query: 219 ------MQVLLPALSPTMTMGTVQRWEKKVGEKLS----EGDLLAEIETDKATIGFEVQE 268
+ VL L P +T+ + E++S +G + E A+ E
Sbjct: 677 RDTDRFLDVLSEQLGPRVTIVDDFLTPENDYEEMSFHDDQGSFVTN-ERSSASDCISSSE 735
Query: 269 EGYLAKIL-----VPEGTRDVPLGTPLCIIVEKEADISAFADYRPTE-----VTDLKPQV 318
EG +P P PL K + S+ P + +T L V
Sbjct: 736 EGSSLTYSSISDHIPPPPLSPPPPPPLPFHDAKPSSRSSDGSRGPAQALAKPLTQLSHPV 795
Query: 319 PPPTPPPVAAVPPTPQPLAP 338
PPP PPP+ P P P AP
Sbjct: 796 PPPPPPPL----PPPVPCAP 811
>gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo
sapiens]
Length = 406
Score = 46.2 bits (108), Expect = 9e-05
Identities = 37/113 (32%), Positives = 44/113 (38%), Gaps = 21/113 (18%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAP--CPATPAGPKGRVFVSPLAKKLA 365
P L PQ+P P PV +PP P P+ P P P P P P V P ++
Sbjct: 231 PALCVHLVPQLPRPPVLPVPPMPPRP-PMVPMPPRPPIAPMPPMAP-----VPPGSRMAP 284
Query: 366 VEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTG 418
V G + V P + V P P PTGP MAPVP G
Sbjct: 285 VPPGPRMAPVPPWPP-------------MAPVPPWPPMAPVPTGPPMAPVPPG 324
Score = 45.1 bits (105), Expect = 2e-04
Identities = 37/110 (33%), Positives = 44/110 (40%), Gaps = 13/110 (11%)
Query: 316 PQVPPPTPPPVAAVPP-TPQP----LAPTPSAP--CPATPAGPKGRVFVSPLAKKLAVEK 368
P VP P PP+A +PP P P +AP P P P P P V P V
Sbjct: 257 PMVPMPPRPPIAPMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPMAP--VPPWPPMAPVPT 314
Query: 369 GIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTG 418
G + V P R+ + VP P P P GP MAP+P G
Sbjct: 315 GPPMAPVPPGPPMARVPPGPPMARVP----PGPPMAPLPPGPPMAPLPPG 360
Score = 37.7 bits (86), Expect = 0.033
Identities = 34/111 (30%), Positives = 43/111 (38%), Gaps = 25/111 (22%)
Query: 307 RPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPA-TPAGPKGRVFVSPLAKKLA 365
R V P P P PP+A VP P P+AP P P A P GP P+A+
Sbjct: 290 RMAPVPPWPPMAPVPPWPPMAPVPTGP-PMAPVPPGPPMARVPPGP-------PMAR--- 338
Query: 366 VEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVP 416
V G + + P + + P P P GP MAP+P
Sbjct: 339 VPPGPPMAPLPPGPP-------------MAPLPPGPPMAPLPPGPPMAPLP 376
>gi|148613878 acrosin precursor [Homo sapiens]
Length = 421
Score = 45.4 bits (106), Expect = 2e-04
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
Query: 316 PQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKG 369
P PPP PPP + +PP P P PTPS +T P+G F L + + V KG
Sbjct: 348 PSPPPPPPPPASPLPPPPPPPPPTPS----STTKLPQGLSFAKRLQQLIEVLKG 397
Score = 33.5 bits (75), Expect = 0.63
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 6/39 (15%)
Query: 319 PPPTP----PPVAAV--PPTPQPLAPTPSAPCPATPAGP 351
PPP P PP A PP+P P P P++P P P P
Sbjct: 330 PPPRPLPPRPPAAQPRPPPSPPPPPPPPASPLPPPPPPP 368
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 5/49 (10%)
Query: 308 PTEVTDLKPQVPPPTPPPVAA-----VPPTPQPLAPTPSAPCPATPAGP 351
P T P + PP P++A P P+PL P P A P P P
Sbjct: 302 PPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSP 350
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 45.1 bits (105), Expect = 2e-04
Identities = 61/245 (24%), Positives = 87/245 (35%), Gaps = 21/245 (8%)
Query: 180 TLDSSAAPTPQAAPAPTPAATASP-PTPSAQAPGSSYPPHMQVL-LPALSPTMTMGTVQR 237
T D+ AAPTP AP P P +P P P +A + P Q+ LP P + VQ
Sbjct: 3236 TPDAKAAPTPTPAPVPVPVPLPAPAPAPHGEARILTVTPSNQLQGLPLTPPVVVTHGVQI 3295
Query: 238 WEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKE 297
GE E +I T + + + +P T+ G P +
Sbjct: 3296 VHSS-GELFQE-YRYGDIRTYHPPAQLTHTQFPAASSVGLPSRTKTAAQGPP-----PEG 3348
Query: 298 ADISAFADYRPTEVTDLKPQVPP-----PTPPPVAAVPPTPQPLAPTPS-APCPATPAGP 351
+ + T+ P PP P PP + +P Q T + P PAGP
Sbjct: 3349 EPLQPPQPVQSTQPAQPAPPCPPSQLGQPGQPPSSKMPQVSQEAKGTQTGVEQPRLPAGP 3408
Query: 352 KGRVFVSPLAKKLAVEKG-IDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPT-G 409
R P V++ + P K D+ +P++ AP VP T G
Sbjct: 3409 ANR----PPEPHTQVQRAQAETGPTSFPSPVSVSMKPDLPVSLPTQTAPKQPLFVPTTSG 3464
Query: 410 PGMAP 414
P P
Sbjct: 3465 PSTPP 3469
Score = 34.3 bits (77), Expect = 0.37
Identities = 42/189 (22%), Positives = 61/189 (32%), Gaps = 22/189 (11%)
Query: 189 PQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKVGEKLSE 248
PQ A P PA P S P H+ V A +P + V + E ++
Sbjct: 3134 PQRASTPQPAPAGVPALASQHPPEEEVHYHLPV-ARATAPVQSEVLVMQSEYRLHPYTVP 3192
Query: 249 GDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADISAFADYRP 308
D+ + + + + +G VP + KEA
Sbjct: 3193 RDVRIMVHPHVTAVSEQPR---------AADGVVKVPPASKAPQQPGKEA---------- 3233
Query: 309 TEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEK 368
+ D K P PTP PV P P P AP P P ++ PL + V
Sbjct: 3234 AKTPDAK-AAPTPTPAPVPVPVPLPAP-APAPHGEARILTVTPSNQLQGLPLTPPVVVTH 3291
Query: 369 GIDLTQVKG 377
G+ + G
Sbjct: 3292 GVQIVHSSG 3300
Score = 33.1 bits (74), Expect = 0.82
Identities = 45/197 (22%), Positives = 77/197 (39%), Gaps = 25/197 (12%)
Query: 169 KPEDIEAFKNYTLDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP 228
KP+++E ++ + TP++AP + +PP+ PP + V+ +P
Sbjct: 1603 KPKEVEKQED---TENHPKTPESAPENKDSELKTPPSVG--------PPSVTVVTLESAP 1651
Query: 229 TMTMGTVQRWEKKVGEKLSEGDLLAEIET-DKATIGFEVQEEGYLAKILVPEGTR-DVPL 286
+ EK G+K E L+ E +T + AT+ E + A V + + D+P
Sbjct: 1652 SAL-------EKTTGDKTVEAPLVTEEKTVEPATVSEEAKPASEPAPAPVEQLEQVDLPP 1704
Query: 287 GTPLCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPA 346
G +KEA + A D P + P P A+ + P P + P
Sbjct: 1705 GAD----PDKEAAMMP-AGVEEGSSGDQPPYLDAKPPTPGASFSQAESNVDPEPDSTQPL 1759
Query: 347 TPAGPKGRVFVSPLAKK 363
+ K P A+K
Sbjct: 1760 SKPAQKSEEANEPKAEK 1776
>gi|96974985 coiled-coil and C2 domain containing 1A [Homo sapiens]
Length = 951
Score = 45.1 bits (105), Expect = 2e-04
Identities = 70/273 (25%), Positives = 101/273 (36%), Gaps = 54/273 (19%)
Query: 183 SSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMGTVQRWEKKV 242
S P P P P+ + PPTP+ + PP + LL AL M +R++
Sbjct: 309 SCLPPPPDQLPPDPPSPPSQPPTPATAPSTTEVPPPPRTLLEALEQRM-----ERYQVAA 363
Query: 243 GEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTP------------- 289
+ S+GD ++ ++ + A V VP G P
Sbjct: 364 AQAKSKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLEATKPTQQ 423
Query: 290 LCIIVEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAP---TP-SAPCP 345
+ V + A A D P + D +VP PVA PT QP AP TP S P
Sbjct: 424 SLVGVLETAMKLANQDEGPEDEED---EVPKKQNSPVA---PTAQPKAPPSRTPQSGSAP 477
Query: 346 ATPAGPKGR--------VFVSPLAKKL------AVEKG------IDLTQVKGTGPDGRIT 385
A PK F+ K+L A +K + L Q KG P +
Sbjct: 478 TAKAPPKATSTRAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEAS 537
Query: 386 KKDIDSFVPSKVAPAPA-----AVVPPTGPGMA 413
+ + + +KV PAP A+V GPG++
Sbjct: 538 RNGLPVDI-TKVPPAPVNKDDFALVQRPGPGLS 569
Score = 37.4 bits (85), Expect = 0.043
Identities = 54/248 (21%), Positives = 88/248 (35%), Gaps = 26/248 (10%)
Query: 177 KNYTLDSSAAPTPQA---APAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSPTMTMG 233
K +D + P P A PA TP + P P+ AP + P +V L S T
Sbjct: 182 KGNAIDEADIPPPVAIGKGPASTPTYS---PAPTQPAPRIASAPEPRVTLEGPSATAPAS 238
Query: 234 TVQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCII 293
+ + ++ LA++++ Q + LA + + +
Sbjct: 239 SPGLAKPQMPPGPCSPGPLAQLQSR--------QRDYKLAALHAKQQGDTTAAARHFRVA 290
Query: 294 VEKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKG 353
+A + A + P +++ L PPP P PP+P PTP+ T P
Sbjct: 291 KSFDAVLEALSRGEPVDLSCL---PPPPDQLP--PDPPSPPSQPPTPATAPSTTEVPPPP 345
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPD------GRITKKDIDSFVPSKVAPAPAAVVPP 407
R + L +++ + Q K G RI K+ D+ K A P
Sbjct: 346 RTLLEALEQRME-RYQVAAAQAKSKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELP 404
Query: 408 TGPGMAPV 415
PG P+
Sbjct: 405 VPPGFPPI 412
>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
Length = 1426
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/169 (27%), Positives = 68/169 (40%), Gaps = 30/169 (17%)
Query: 205 TPS-AQAPGSSYPPHMQVLLPALSPTMTMGT----VQRWEKKVGEKLSEGDLLAEIETDK 259
TPS A AP SS P H Q A PT T V + ++ K +E L ++ET
Sbjct: 144 TPSNATAPRSSTPSHGQTT--ATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVET-- 199
Query: 260 ATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCII------VEKEADISAFADYRPTEVTD 313
+ F +Q ++ T PL T + + + ++ A D ++ T
Sbjct: 200 -IVSFHIQN---ISNNKTERST--APLNTQISALRNDPKPLPQQPPAPANQDQNSSQNTR 253
Query: 314 LKPQVPPPTPPPVAAVPPTP---------QPLAPTPSAPCPATPAGPKG 353
L+P P P P P A PP P L P+ +P +TP P G
Sbjct: 254 LQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDG 302
Score = 32.0 bits (71), Expect = 1.8
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 9/72 (12%)
Query: 170 PEDIEAFKNYTLDSSAAPTP-----QAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLP 224
P + K+ + SAA +P + PAP+P T+S P P Q+PG PP+ + L
Sbjct: 899 PAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSS-PKPPLQSPG--IPPNHKAPLT 955
Query: 225 ALSPTMTMGTVQ 236
SP M +G V+
Sbjct: 956 MASPAM-LGNVE 966
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 45.1 bits (105), Expect = 2e-04
Identities = 60/264 (22%), Positives = 80/264 (30%), Gaps = 59/264 (22%)
Query: 184 SAAPTPQAAPAPTPAATASP-PTPSAQAPGS-SYPPHMQVLLPALSPTMTMGTVQRWEKK 241
++AP P + A PA+T++P P P S S P L P L+ T
Sbjct: 1750 ASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAPVLASTSAPVPASP---- 1805
Query: 242 VGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIVEKEADIS 301
LA + A++ V A I P TP+ V A ++
Sbjct: 1806 ----------LAPVSAS-ASVSASVPASTSAAAITSSSAPASAPAPTPILASVSTPASVT 1854
Query: 302 AFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPT--PSAPCPATPAGPKGRVFVSP 359
A + PTP P A+ P P APT SAP + P P
Sbjct: 1855 ILASASIPILASALASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPAS------ 1908
Query: 360 LAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAPVPTGV 419
S APAP V P AP T
Sbjct: 1909 ----------------------------------ASAPAPAPTPVSAPNPAPPAPAQTQA 1934
Query: 420 FTDIPISNIRRVIAQRLMQSKQTI 443
T P+ N + +Q Q +I
Sbjct: 1935 QTHKPVQNPLQTTSQSSKQPPPSI 1958
Score = 34.7 bits (78), Expect = 0.28
Identities = 32/123 (26%), Positives = 47/123 (38%), Gaps = 17/123 (13%)
Query: 310 EVTDLKPQVPPPTPPPVAAVPPTPQPLAPTP---SAPCPAT----PAGPKGRVFVSPLAK 362
+ T ++ + PP+A+ P P A P SAP PAT PA V S LA
Sbjct: 1733 QATGIQQAQSSASVPPLASAPLPPSTSASVPASTSAPLPATLTPVPASTSAPVPASTLAP 1792
Query: 363 KLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKV--APAPAAVVPPTGPGMAPVPTGVF 420
LA P + + V + V + + AA+ + P AP PT +
Sbjct: 1793 VLA--------STSAPVPASPLAPVSASASVSASVPASTSAAAITSSSAPASAPAPTPIL 1844
Query: 421 TDI 423
+
Sbjct: 1845 ASV 1847
Score = 30.4 bits (67), Expect = 5.3
Identities = 36/117 (30%), Positives = 47/117 (40%), Gaps = 20/117 (17%)
Query: 309 TEVTDLKPQVPPPTPP-PV--AAVPPTPQP------------LAPTPSAPCPATPAGPKG 353
TE DL P PPP PP P+ +VPP QP LA PS P P
Sbjct: 1053 TEKKDLPPPPPPPQPPAPIQPQSVPPPIQPEAEKFPSTETATLAQKPSQD-TEKPLEPVS 1111
Query: 354 RVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVP---SKVAPAPAAVVPP 407
V V P A K ++ + VK ++ KD+ P S+ A + +PP
Sbjct: 1112 TVQVEP-AVKTVNQQTMAAPVVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLPP 1167
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 45.1 bits (105), Expect = 2e-04
Identities = 21/45 (46%), Positives = 25/45 (55%)
Query: 315 KPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSP 359
+PQ PPP PPP A+P P +APTPS+P P P SP
Sbjct: 1468 QPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSP 1512
Score = 40.0 bits (92), Expect = 0.007
Identities = 20/44 (45%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 308 PTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGP 351
PT + P +PPP PPP PP P P A P A P PA P
Sbjct: 1491 PTPSSPPPPPLPPP-PPPAMPSPPPPPPPAAAPLAAPPEEPAAP 1533
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 304 ADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSP 359
A+ T L + PPPTPPP PTPQP P P P P PA P V+P
Sbjct: 1442 ANSNGTPEPPLLEEKPPPTPPPA----PTPQPQPPPP--PPPPQPALPSPPPLVAP 1491
Score = 37.0 bits (84), Expect = 0.057
Identities = 16/36 (44%), Positives = 20/36 (55%)
Query: 316 PQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGP 351
PQ P+PPP+ A P+ P P P P PA P+ P
Sbjct: 1478 PQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Score = 32.3 bits (72), Expect = 1.4
Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 2/27 (7%)
Query: 319 PPPTPPPVAA--VPPTPQPLAPTPSAP 343
PPP PPP AA P +P AP+P P
Sbjct: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 31.6 bits (70), Expect = 2.4
Identities = 16/48 (33%), Positives = 19/48 (39%), Gaps = 3/48 (6%)
Query: 181 LDSSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP 228
L+ PTP AP P P PP P P PP + P+ P
Sbjct: 1453 LEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS---PPPLVAPTPSSPP 1497
Score = 31.6 bits (70), Expect = 2.4
Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 4/48 (8%)
Query: 186 APTPQAAPAPTPA----ATASPPTPSAQAPGSSYPPHMQVLLPALSPT 229
APTPQ P P P A SPP A P S PP + P P+
Sbjct: 1464 APTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS 1511
Score = 31.2 bits (69), Expect = 3.1
Identities = 21/63 (33%), Positives = 22/63 (34%), Gaps = 12/63 (19%)
Query: 314 LKPQVPPPTPPPVAAVP------------PTPQPLAPTPSAPCPATPAGPKGRVFVSPLA 361
L P PP P V A P P P P P P AP G +F S
Sbjct: 1010 LDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKP 1069
Query: 362 KKL 364
KKL
Sbjct: 1070 KKL 1072
Score = 30.8 bits (68), Expect = 4.1
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 185 AAPTPQAAPAPTPAATASPPTPSAQAPGSSYPP 217
A P+P APTP++ PP P P PP
Sbjct: 1481 ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Score = 29.6 bits (65), Expect = 9.0
Identities = 30/111 (27%), Positives = 39/111 (35%), Gaps = 40/111 (36%)
Query: 313 DLKPQVPPPTPPPVAAVPPTPQPL---------APTPSAPCPATPAGPKGRVFVSPLAKK 363
D PQ PPP PP PP P PL P+AP P +
Sbjct: 830 DGAPQPPPPPPP-----PPPPMPLQLEAHLRSHGLEPAAPSP-----------------R 867
Query: 364 LAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTGPGMAP 414
L E+ +D P G + ++ + + P AP V PP G P
Sbjct: 868 LRPEESLD--------PPGAM-QELLGALEPLPPAPGDTGVGPPNSEGKDP 909
>gi|169163027 PREDICTED: similar to Putative acrosin-like protease
[Homo sapiens]
Length = 355
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/54 (42%), Positives = 29/54 (53%), Gaps = 4/54 (7%)
Query: 316 PQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGRVFVSPLAKKLAVEKG 369
P PPP PPP + +PP P P PTPS +T P+G F L + + V KG
Sbjct: 282 PSPPPPPPPPPSPLPPPPPPPPPTPS----STTKLPQGLSFAKRLQQLIEVLKG 331
Score = 33.1 bits (74), Expect = 0.82
Identities = 16/37 (43%), Positives = 16/37 (43%), Gaps = 4/37 (10%)
Query: 319 PPPTP----PPVAAVPPTPQPLAPTPSAPCPATPAGP 351
PPP P PP A P P P P P P P P P
Sbjct: 264 PPPRPLPPRPPAAQPRPPPSPPPPPPPPPSPLPPPPP 300
Score = 31.2 bits (69), Expect = 3.1
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 5/49 (10%)
Query: 308 PTEVTDLKPQVPPPTPPPVAA-----VPPTPQPLAPTPSAPCPATPAGP 351
P T P + PP P++A P P+PL P P A P P P
Sbjct: 236 PPPPTTRPPPIRPPFSHPLSAHLPWYFQPPPRPLPPRPPAAQPRPPPSP 284
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/119 (31%), Positives = 47/119 (39%), Gaps = 21/119 (17%)
Query: 316 PQVPPPTPPPVA-----AVPPTPQPL---------APTPSAPCPATPAGPKGRVFVSPLA 361
P VPPP PPP AVPP P PL AP P AP P+ P R +P+
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR--AAPVC 407
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTG----PGMAPVP 416
+ + V + +V+G P PS A PP+G P AP P
Sbjct: 408 ETVPVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP 465
Score = 32.0 bits (71), Expect = 1.8
Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 44/175 (25%)
Query: 308 PTEVTDLKPQVPPPTPPPVA------------------AVPPTPQPLA-----PTPSAPC 344
P + P V P PPP+A VP P P P P P
Sbjct: 371 PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP 430
Query: 345 PATPAG--PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPA 402
P P G P V V+ LA G+ T GP VP P+
Sbjct: 431 PLPPPGIRPSSPVTVTALAHP---PSGLHPTPSTAPGP-----------HVPLMPPSPPS 476
Query: 403 AVVPPTGPGMAPVPTGVFTD---IPISNIRRVIAQRLM--QSKQTIPHYYLSIDV 452
V+P + P P V +D + + IR+ I R + Q +Q H + DV
Sbjct: 477 QVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDV 531
Score = 31.6 bits (70), Expect = 2.4
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 7/53 (13%)
Query: 184 SAAPTPQAAPAPTPAATA-------SPPTPSAQAPGSSYPPHMQVLLPALSPT 229
++ P P P P P ATA PP P APG +P + P + P+
Sbjct: 345 TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Score = 30.8 bits (68), Expect = 4.1
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 183 SSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP--TMTMGTVQR--W 238
S PTP AP P PP+P +Q +S P LP +S ++ + +++
Sbjct: 453 SGLHPTPSTAPGPH--VPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQ 510
Query: 239 EKKVGEKLSEGDLLAEIETDKATI 262
+KV E+ + IE D ATI
Sbjct: 511 LRKVEEQREQEAKHERIENDVATI 534
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/46 (34%), Positives = 18/46 (39%), Gaps = 13/46 (28%)
Query: 319 PPPTPPP-------------VAAVPPTPQPLAPTPSAPCPATPAGP 351
PPP PPP + + PP P P P P A PA P
Sbjct: 324 PPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 14/72 (19%)
Query: 294 VEKEADISAFADYRPTEVTDLKPQVPPPTPPP-------------VAAVPPTPQPLAPTP 340
V + A + P +++ PPP PPP V A+ P L PTP
Sbjct: 400 VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 341 S-APCPATPAGP 351
S AP P P P
Sbjct: 460 STAPGPHVPLMP 471
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/119 (31%), Positives = 47/119 (39%), Gaps = 21/119 (17%)
Query: 316 PQVPPPTPPPVA-----AVPPTPQPL---------APTPSAPCPATPAGPKGRVFVSPLA 361
P VPPP PPP AVPP P PL AP P AP P+ P R +P+
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR--AAPVC 407
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTG----PGMAPVP 416
+ + V + +V+G P PS A PP+G P AP P
Sbjct: 408 ETVPVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP 465
Score = 32.0 bits (71), Expect = 1.8
Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 44/175 (25%)
Query: 308 PTEVTDLKPQVPPPTPPPVA------------------AVPPTPQPLA-----PTPSAPC 344
P + P V P PPP+A VP P P P P P
Sbjct: 371 PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP 430
Query: 345 PATPAG--PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPA 402
P P G P V V+ LA G+ T GP VP P+
Sbjct: 431 PLPPPGIRPSSPVTVTALAHP---PSGLHPTPSTAPGP-----------HVPLMPPSPPS 476
Query: 403 AVVPPTGPGMAPVPTGVFTD---IPISNIRRVIAQRLM--QSKQTIPHYYLSIDV 452
V+P + P P V +D + + IR+ I R + Q +Q H + DV
Sbjct: 477 QVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDV 531
Score = 31.6 bits (70), Expect = 2.4
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 7/53 (13%)
Query: 184 SAAPTPQAAPAPTPAATA-------SPPTPSAQAPGSSYPPHMQVLLPALSPT 229
++ P P P P P ATA PP P APG +P + P + P+
Sbjct: 345 TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Score = 30.8 bits (68), Expect = 4.1
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 183 SSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP--TMTMGTVQR--W 238
S PTP AP P PP+P +Q +S P LP +S ++ + +++
Sbjct: 453 SGLHPTPSTAPGPH--VPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQ 510
Query: 239 EKKVGEKLSEGDLLAEIETDKATI 262
+KV E+ + IE D ATI
Sbjct: 511 LRKVEEQREQEAKHERIENDVATI 534
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/46 (34%), Positives = 18/46 (39%), Gaps = 13/46 (28%)
Query: 319 PPPTPPP-------------VAAVPPTPQPLAPTPSAPCPATPAGP 351
PPP PPP + + PP P P P P A PA P
Sbjct: 324 PPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 14/72 (19%)
Query: 294 VEKEADISAFADYRPTEVTDLKPQVPPPTPPP-------------VAAVPPTPQPLAPTP 340
V + A + P +++ PPP PPP V A+ P L PTP
Sbjct: 400 VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 341 S-APCPATPAGP 351
S AP P P P
Sbjct: 460 STAPGPHVPLMP 471
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/119 (31%), Positives = 47/119 (39%), Gaps = 21/119 (17%)
Query: 316 PQVPPPTPPPVA-----AVPPTPQPL---------APTPSAPCPATPAGPKGRVFVSPLA 361
P VPPP PPP AVPP P PL AP P AP P+ P R +P+
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR--AAPVC 407
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTG----PGMAPVP 416
+ + V + +V+G P PS A PP+G P AP P
Sbjct: 408 ETVPVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP 465
Score = 32.0 bits (71), Expect = 1.8
Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 44/175 (25%)
Query: 308 PTEVTDLKPQVPPPTPPPVA------------------AVPPTPQPLA-----PTPSAPC 344
P + P V P PPP+A VP P P P P P
Sbjct: 371 PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP 430
Query: 345 PATPAG--PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPA 402
P P G P V V+ LA G+ T GP VP P+
Sbjct: 431 PLPPPGIRPSSPVTVTALAHP---PSGLHPTPSTAPGP-----------HVPLMPPSPPS 476
Query: 403 AVVPPTGPGMAPVPTGVFTD---IPISNIRRVIAQRLM--QSKQTIPHYYLSIDV 452
V+P + P P V +D + + IR+ I R + Q +Q H + DV
Sbjct: 477 QVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDV 531
Score = 31.6 bits (70), Expect = 2.4
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 7/53 (13%)
Query: 184 SAAPTPQAAPAPTPAATA-------SPPTPSAQAPGSSYPPHMQVLLPALSPT 229
++ P P P P P ATA PP P APG +P + P + P+
Sbjct: 345 TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Score = 30.8 bits (68), Expect = 4.1
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 183 SSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP--TMTMGTVQR--W 238
S PTP AP P PP+P +Q +S P LP +S ++ + +++
Sbjct: 453 SGLHPTPSTAPGPH--VPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQ 510
Query: 239 EKKVGEKLSEGDLLAEIETDKATI 262
+KV E+ + IE D ATI
Sbjct: 511 LRKVEEQREQEAKHERIENDVATI 534
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/46 (34%), Positives = 18/46 (39%), Gaps = 13/46 (28%)
Query: 319 PPPTPPP-------------VAAVPPTPQPLAPTPSAPCPATPAGP 351
PPP PPP + + PP P P P P A PA P
Sbjct: 324 PPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 14/72 (19%)
Query: 294 VEKEADISAFADYRPTEVTDLKPQVPPPTPPP-------------VAAVPPTPQPLAPTP 340
V + A + P +++ PPP PPP V A+ P L PTP
Sbjct: 400 VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 341 S-APCPATPAGP 351
S AP P P P
Sbjct: 460 STAPGPHVPLMP 471
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/119 (31%), Positives = 47/119 (39%), Gaps = 21/119 (17%)
Query: 316 PQVPPPTPPPVA-----AVPPTPQPL---------APTPSAPCPATPAGPKGRVFVSPLA 361
P VPPP PPP AVPP P PL AP P AP P+ P R +P+
Sbjct: 350 PPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPSPPVAR--AAPVC 407
Query: 362 KKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVPPTG----PGMAPVP 416
+ + V + +V+G P PS A PP+G P AP P
Sbjct: 408 ETVPVHP-LPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGP 465
Score = 32.0 bits (71), Expect = 1.8
Identities = 45/175 (25%), Positives = 59/175 (33%), Gaps = 44/175 (25%)
Query: 308 PTEVTDLKPQVPPPTPPPVA------------------AVPPTPQPLA-----PTPSAPC 344
P + P V P PPP+A VP P P P P P
Sbjct: 371 PPAPLQIAPGVLHPAPPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPP 430
Query: 345 PATPAG--PKGRVFVSPLAKKLAVEKGIDLTQVKGTGPDGRITKKDIDSFVPSKVAPAPA 402
P P G P V V+ LA G+ T GP VP P+
Sbjct: 431 PLPPPGIRPSSPVTVTALAHP---PSGLHPTPSTAPGP-----------HVPLMPPSPPS 476
Query: 403 AVVPPTGPGMAPVPTGVFTD---IPISNIRRVIAQRLM--QSKQTIPHYYLSIDV 452
V+P + P P V +D + + IR+ I R + Q +Q H + DV
Sbjct: 477 QVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERIENDV 531
Score = 31.6 bits (70), Expect = 2.4
Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 7/53 (13%)
Query: 184 SAAPTPQAAPAPTPAATA-------SPPTPSAQAPGSSYPPHMQVLLPALSPT 229
++ P P P P P ATA PP P APG +P + P + P+
Sbjct: 345 TSTPPPPVPPPPPPPATALQAPAVPPPPAPLQIAPGVLHPAPPPIAPPLVQPS 397
Score = 30.8 bits (68), Expect = 4.1
Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 183 SSAAPTPQAAPAPTPAATASPPTPSAQAPGSSYPPHMQVLLPALSP--TMTMGTVQR--W 238
S PTP AP P PP+P +Q +S P LP +S ++ + +++
Sbjct: 453 SGLHPTPSTAPGPH--VPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRKGIQ 510
Query: 239 EKKVGEKLSEGDLLAEIETDKATI 262
+KV E+ + IE D ATI
Sbjct: 511 LRKVEEQREQEAKHERIENDVATI 534
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/46 (34%), Positives = 18/46 (39%), Gaps = 13/46 (28%)
Query: 319 PPPTPPP-------------VAAVPPTPQPLAPTPSAPCPATPAGP 351
PPP PPP + + PP P P P P A PA P
Sbjct: 324 PPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVP 369
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/72 (30%), Positives = 28/72 (38%), Gaps = 14/72 (19%)
Query: 294 VEKEADISAFADYRPTEVTDLKPQVPPPTPPP-------------VAAVPPTPQPLAPTP 340
V + A + P +++ PPP PPP V A+ P L PTP
Sbjct: 400 VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTP 459
Query: 341 S-APCPATPAGP 351
S AP P P P
Sbjct: 460 STAPGPHVPLMP 471
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,726,453
Number of Sequences: 37866
Number of extensions: 1810150
Number of successful extensions: 37693
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 403
Number of HSP's successfully gapped in prelim test: 637
Number of HSP's that attempted gapping in prelim test: 18834
Number of HSP's gapped (non-prelim): 11945
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.