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Search of human proteins with 31543910
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543910 ubiquitin specific protease 1 [Homo sapiens]
(785 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|63053524 ubiquitin specific protease 1 [Homo sapiens] 1570 0.0
gi|63053522 ubiquitin specific protease 1 [Homo sapiens] 1570 0.0
gi|31543910 ubiquitin specific protease 1 [Homo sapiens] 1570 0.0
gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens] 89 2e-17
gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo sap... 88 3e-17
gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo sapi... 88 3e-17
gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens] 86 1e-16
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens] 80 6e-15
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens] 80 6e-15
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 79 2e-14
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 68 4e-11
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 67 8e-11
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 67 8e-11
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 67 8e-11
gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens] 66 1e-10
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 66 1e-10
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 66 1e-10
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 65 2e-10
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 65 2e-10
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 65 2e-10
gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens] 64 4e-10
gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens] 64 4e-10
gi|41055953 ubiquitin thioesterase 40 [Homo sapiens] 64 5e-10
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 63 9e-10
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 63 9e-10
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 63 1e-09
gi|21361749 ubiquitin thioesterase 49 [Homo sapiens] 61 4e-09
gi|62243586 ubiquitin-specific protease 21 [Homo sapiens] 60 8e-09
gi|74027267 ubiquitin-specific protease 21 [Homo sapiens] 60 8e-09
gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo ... 59 2e-08
>gi|63053524 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 1570 bits (4064), Expect = 0.0
Identities = 785/785 (100%), Positives = 785/785 (100%)
Query: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV
Sbjct: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
Query: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK
Sbjct: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
Query: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR
Sbjct: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
Query: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK
Sbjct: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
Query: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
Sbjct: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
Query: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK
Sbjct: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
Query: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ
Sbjct: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
Query: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT
Sbjct: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
Query: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL
Sbjct: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
Query: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
Sbjct: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
Query: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK
Sbjct: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
Query: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD
Sbjct: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
Query: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL
Sbjct: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
Query: 781 FYKKL 785
FYKKL
Sbjct: 781 FYKKL 785
>gi|63053522 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 1570 bits (4064), Expect = 0.0
Identities = 785/785 (100%), Positives = 785/785 (100%)
Query: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV
Sbjct: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
Query: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK
Sbjct: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
Query: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR
Sbjct: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
Query: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK
Sbjct: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
Query: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
Sbjct: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
Query: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK
Sbjct: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
Query: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ
Sbjct: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
Query: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT
Sbjct: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
Query: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL
Sbjct: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
Query: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
Sbjct: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
Query: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK
Sbjct: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
Query: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD
Sbjct: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
Query: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL
Sbjct: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
Query: 781 FYKKL 785
FYKKL
Sbjct: 781 FYKKL 785
>gi|31543910 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 1570 bits (4064), Expect = 0.0
Identities = 785/785 (100%), Positives = 785/785 (100%)
Query: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV
Sbjct: 1 MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQV 60
Query: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK
Sbjct: 61 VPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKK 120
Query: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR
Sbjct: 121 EALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRR 180
Query: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK
Sbjct: 181 LLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPK 240
Query: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
Sbjct: 241 EEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT 300
Query: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK
Sbjct: 301 RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGK 360
Query: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ
Sbjct: 361 ITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQ 420
Query: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT
Sbjct: 421 IGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKT 480
Query: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL
Sbjct: 481 EMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGL 540
Query: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
Sbjct: 541 EFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV 600
Query: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK
Sbjct: 601 TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNK 660
Query: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD
Sbjct: 661 KNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSDTTGTHESDRNKESSD 720
Query: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL
Sbjct: 721 QTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLL 780
Query: 781 FYKKL 785
FYKKL
Sbjct: 781 FYKKL 785
>gi|32698815 ubiquitin thiolesterase 12 [Homo sapiens]
Length = 370
Score = 89.0 bits (219), Expect = 2e-17
Identities = 57/179 (31%), Positives = 90/179 (50%), Gaps = 26/179 (14%)
Query: 426 VEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTL 485
V+++FQG L TRCL CE+++ + EDF D+SV V+++ ++
Sbjct: 172 VDEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQN-------------------TSI 212
Query: 486 RWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCY 545
+ F++ E + E KY+CE C EA + + K+P ++ +HLK F + Y
Sbjct: 213 THCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMD-QLHRY 271
Query: 546 GGGLSKINTPLLTPLKLSLEEWSTKPTNDS--YGLFAVVMHSGITISSGHYTASVKVTD 602
+K++ ++ PL+L L S TN Y L AVV+H G + GHY A VK D
Sbjct: 272 ----TKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHD 326
Score = 62.4 bits (150), Expect = 2e-09
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 33/146 (22%)
Query: 80 FVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDS 139
+ GL N GNTCY NS+LQ LYFC F+ +++ K + K E+
Sbjct: 38 YFGLVNFGNTCYCNSVLQALYFCRPFRE------KVLAYKSQPRKKES------------ 79
Query: 140 LASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHD 199
L+ L L S+ + + P P++ + LR+ N +++ Y+Q D
Sbjct: 80 -----LLTCLADLFHSIATQKKKVGVIP----------PKKFITRLRKENELFDNYMQQD 124
Query: 200 AQEVLQCILGNIQETCQLLKKEEVKN 225
A E L +L I + Q +K+E +N
Sbjct: 125 AHEFLNYLLNTIADILQEERKQEKQN 150
>gi|197116355 ubiquitin specific peptidase 46 isoform 2 [Homo
sapiens]
Length = 359
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 30/195 (15%)
Query: 407 NVNEVKPINKGEEQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELS 466
N+NE NK E V ++FQG L TRCL CE+++ + EDF D+SV V+++
Sbjct: 146 NMNEPAENNKPE----LTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--- 198
Query: 467 KVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPE 526
++ + F++ E + E KY+CE C EA++ + K+P
Sbjct: 199 ----------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM 242
Query: 527 VITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTN--DSYGLFAVVMH 584
++ +HLK F + Y +K++ ++ PL+L L S+ N Y L AVV+H
Sbjct: 243 ILALHLKRFKYME-QLHRY----TKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVH 297
Query: 585 SGITISSGHYTASVK 599
G + GHY VK
Sbjct: 298 CGSGPNRGHYITIVK 312
Score = 67.4 bits (163), Expect = 5e-11
Identities = 46/146 (31%), Positives = 67/146 (45%), Gaps = 33/146 (22%)
Query: 80 FVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDS 139
+ GL N GNTCY NS+LQ LYFC F+ V L +A QK K N
Sbjct: 27 YFGLVNFGNTCYCNSVLQALYFCRPFRENV-------------LAYKAQQKKKEN----- 68
Query: 140 LASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHD 199
L+ L L S+ + + P P++ ++ LR+ N +++ Y+Q D
Sbjct: 69 -----LLTCLADLFHSIATQKKKVGVIP----------PKKFISRLRKENDLFDNYMQQD 113
Query: 200 AQEVLQCILGNIQETCQLLKKEEVKN 225
A E L +L I + Q KK+E +N
Sbjct: 114 AHEFLNYLLNTIADILQEEKKQEKQN 139
>gi|31377709 ubiquitin specific peptidase 46 isoform 1 [Homo
sapiens]
Length = 366
Score = 88.2 bits (217), Expect = 3e-17
Identities = 60/195 (30%), Positives = 95/195 (48%), Gaps = 30/195 (15%)
Query: 407 NVNEVKPINKGEEQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELS 466
N+NE NK E V ++FQG L TRCL CE+++ + EDF D+SV V+++
Sbjct: 153 NMNEPAENNKPE----LTWVHEIFQGTLTNETRCLNCETVSSKDEDFLDLSVDVEQN--- 205
Query: 467 KVEESSEISPEPKTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPE 526
++ + F++ E + E KY+CE C EA++ + K+P
Sbjct: 206 ----------------TSITHCLRDFSNTETLCSEQKYYCETCCSKQEAQKRMRVKKLPM 249
Query: 527 VITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTN--DSYGLFAVVMH 584
++ +HLK F + Y +K++ ++ PL+L L S+ N Y L AVV+H
Sbjct: 250 ILALHLKRFKYME-QLHRY----TKLSYRVVFPLELRLFNTSSDAVNLDRMYDLVAVVVH 304
Query: 585 SGITISSGHYTASVK 599
G + GHY VK
Sbjct: 305 CGSGPNRGHYITIVK 319
Score = 67.4 bits (163), Expect = 5e-11
Identities = 46/146 (31%), Positives = 67/146 (45%), Gaps = 33/146 (22%)
Query: 80 FVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDS 139
+ GL N GNTCY NS+LQ LYFC F+ V L +A QK K N
Sbjct: 34 YFGLVNFGNTCYCNSVLQALYFCRPFRENV-------------LAYKAQQKKKEN----- 75
Query: 140 LASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHD 199
L+ L L S+ + + P P++ ++ LR+ N +++ Y+Q D
Sbjct: 76 -----LLTCLADLFHSIATQKKKVGVIP----------PKKFISRLRKENDLFDNYMQQD 120
Query: 200 AQEVLQCILGNIQETCQLLKKEEVKN 225
A E L +L I + Q KK+E +N
Sbjct: 121 AHEFLNYLLNTIADILQEEKKQEKQN 146
>gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens]
Length = 814
Score = 86.3 bits (212), Expect = 1e-16
Identities = 138/602 (22%), Positives = 235/602 (39%), Gaps = 122/602 (20%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
G+ NLGNTC+ N+++Q L + L D N+ + + K
Sbjct: 191 GITNLGNTCFFNAVMQNL------------------AQTYTLTDLMNEIKESSTKLKIFP 232
Query: 142 SYELICSLQSLIISVEQ----LQASFL-LNPEKYTDELATQPRRLLNTLRELNPMYEGYL 196
S + L L++ + + A FL L+ K T++ P+ L N L + P ++ +
Sbjct: 233 SSD--SQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
Query: 197 QHDAQEVLQCILGNI--QET----CQLLK--KEEVKNVAELPTKVEEIPHPKE--EMNGI 246
Q D+QE+L +L + +ET +LK A+ T+ + + KE +MN I
Sbjct: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
Query: 247 NSIEMDSMRHSEDFKE--------------KLPKGNGKRKSDTEFGNMKKKVKLSK-EHQ 291
+ I + + + +E LP + +G M K L + +H
Sbjct: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
Query: 292 SLE-----ENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSAT 346
EN Q R+ +K +S +S K I + S + + +
Sbjct: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSL 470
Query: 347 KQPSILSKFCSLGKITTNQGVKGQS-KENECDPEEDLGKCESDNTTNGCGLESPGNTVTP 405
S+++ L + T+ K S E+ D + + + ES + G S G+ V P
Sbjct: 471 MFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQP 530
Query: 406 VNVNEVKPINKGE-------EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISV 458
+ P++ G+ + E+ E + + L S +DF +
Sbjct: 531 DG--PLYPLSAGKLLYTKETDSGDKEMAEAISE---------LRLSSTVTGDQDFDRENQ 579
Query: 459 PVQ-EDELSKVEESSEISPEPKTEMKTLRWA-------------ISQFASVERIVGEDKY 504
P+ + L +E S P+ +TL + + QF S+E ++G +K
Sbjct: 580 PLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKL 639
Query: 505 FCENCHH-------------------YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCY 545
CENC YT A + LL +P V+ +HLK F +GL
Sbjct: 640 LCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGL----- 694
Query: 546 GGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMHSGITISSGHYTASV 598
L K+N + PL L L + + ++ YGL+ +V HSG ++ GHYTA V
Sbjct: 695 --SLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSG-SMREGHYTAYV 751
Query: 599 KV 600
KV
Sbjct: 752 KV 753
>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 80.5 bits (197), Expect = 6e-15
Identities = 159/689 (23%), Positives = 261/689 (37%), Gaps = 167/689 (24%)
Query: 17 PSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKREN 76
P++K+ +++ KK K + + QE E+K + A ++ P+N +
Sbjct: 149 PAEKDNGNIELENKKLEKES---KNEQEREKKENM-----------AKENPPMNSPCQ-- 192
Query: 77 LLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCK 136
+ GL+NLGNTC+ N+++Q L P + E LK+ +
Sbjct: 193 -ITVKGLSNLGNTCFFNAVMQNLSQTPVLR--------------ELLKEVKMSGTIVKIE 237
Query: 137 EDSLASYELICSLQSLIISVEQ-----LQASFLLNPEKYTDELATQPRRLLNTLRELNPM 191
LA E L I++E L S LN + T + P+ L + + +
Sbjct: 238 PPDLALTE------PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVR 291
Query: 192 YEGYLQHDAQEVLQCILGNIQ-ETCQLLKK--------------EEVKNVAELPTKVEEI 236
++GY Q D+QE+L+ +L ++ E Q + K EE+KN + K + +
Sbjct: 292 FKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM 351
Query: 237 PHPKEEMNG---INSIEMDSMR-----HSEDFKEKLP---KGNGKRKSDTEFGNMKKKVK 285
P + + G + I D R H LP +GK+ + + N+KK V+
Sbjct: 352 PSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDK--NLKKTVE 409
Query: 286 LSKEHQSLEENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSA 345
E Q EE ++ S K SD K + K ++ + ++K++ K+
Sbjct: 410 --DEDQDSEE-EKDNDSYIKERSDIPSGTSKHLQK-----KAKKQAKKQA-------KNQ 454
Query: 346 TKQPSILSKFCSLGKITTNQGVKGQSKENECDPEEDL----------GKCESDNTTNGCG 395
+Q I K L I T + E E + ++ G + N
Sbjct: 455 RRQQKIQGKVLHLNDICTIDHPEDSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKD 514
Query: 396 LESPGNTVTPVNVNEVKPINKGEEQIGFELVEKLFQGQLVLR--TRCLECESLTERREDF 453
L + V N+ K E++ + + +++ TR L LTE
Sbjct: 515 LNGQAKMIESVTDNQ-----KSTEEVDMKNINMDNDLEVLTSSPTRNLNGAYLTEGSNGE 569
Query: 454 QDIS---------VPVQEDELS------------KVEESSEISPEP-----------KTE 481
DIS + DE++ KV E PE T+
Sbjct: 570 VDISNGFKNLNLNAALHPDEINIEILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTD 629
Query: 482 MKTLRWAISQFASVERIVGEDKYFCENC-----------------HHYTEAERSLLFDKM 524
+++ + QF E++ +K CE C H YT A++ +L
Sbjct: 630 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 689
Query: 525 PEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWST--------KPTNDSY 576
P V+T+HLK F +G L K+N + P L L + T + T Y
Sbjct: 690 PPVLTLHLKRFQQAGF-------NLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLY 742
Query: 577 GLFAVVMHSGITISSGHYTASVKVTDLNS 605
L+ VV HSG T+ SGHYTA K NS
Sbjct: 743 SLYGVVEHSG-TMRSGHYTAYAKARTANS 770
>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 80.5 bits (197), Expect = 6e-15
Identities = 159/689 (23%), Positives = 261/689 (37%), Gaps = 167/689 (24%)
Query: 17 PSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKREN 76
P++K+ +++ KK K + + QE E+K + A ++ P+N +
Sbjct: 149 PAEKDNGNIELENKKLEKES---KNEQEREKKENM-----------AKENPPMNSPCQ-- 192
Query: 77 LLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCK 136
+ GL+NLGNTC+ N+++Q L P + E LK+ +
Sbjct: 193 -ITVKGLSNLGNTCFFNAVMQNLSQTPVLR--------------ELLKEVKMSGTIVKIE 237
Query: 137 EDSLASYELICSLQSLIISVEQ-----LQASFLLNPEKYTDELATQPRRLLNTLRELNPM 191
LA E L I++E L S LN + T + P+ L + + +
Sbjct: 238 PPDLALTE------PLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVR 291
Query: 192 YEGYLQHDAQEVLQCILGNIQ-ETCQLLKK--------------EEVKNVAELPTKVEEI 236
++GY Q D+QE+L+ +L ++ E Q + K EE+KN + K + +
Sbjct: 292 FKGYQQQDSQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSM 351
Query: 237 PHPKEEMNG---INSIEMDSMR-----HSEDFKEKLP---KGNGKRKSDTEFGNMKKKVK 285
P + + G + I D R H LP +GK+ + + N+KK V+
Sbjct: 352 PSFVDRIFGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSVNDK--NLKKTVE 409
Query: 286 LSKEHQSLEENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSA 345
E Q EE ++ S K SD K + K ++ + ++K++ K+
Sbjct: 410 --DEDQDSEE-EKDNDSYIKERSDIPSGTSKHLQK-----KAKKQAKKQA-------KNQ 454
Query: 346 TKQPSILSKFCSLGKITTNQGVKGQSKENECDPEEDL----------GKCESDNTTNGCG 395
+Q I K L I T + E E + ++ G + N
Sbjct: 455 RRQQKIQGKVLHLNDICTIDHPEDSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKD 514
Query: 396 LESPGNTVTPVNVNEVKPINKGEEQIGFELVEKLFQGQLVLR--TRCLECESLTERREDF 453
L + V N+ K E++ + + +++ TR L LTE
Sbjct: 515 LNGQAKMIESVTDNQ-----KSTEEVDMKNINMDNDLEVLTSSPTRNLNGAYLTEGSNGE 569
Query: 454 QDIS---------VPVQEDELS------------KVEESSEISPEP-----------KTE 481
DIS + DE++ KV E PE T+
Sbjct: 570 VDISNGFKNLNLNAALHPDEINIEILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTD 629
Query: 482 MKTLRWAISQFASVERIVGEDKYFCENC-----------------HHYTEAERSLLFDKM 524
+++ + QF E++ +K CE C H YT A++ +L
Sbjct: 630 ECSIQHCLYQFTRNEKLRDANKLLCEVCTRRQCNGPKANIKGERKHVYTNAKKQMLISLA 689
Query: 525 PEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWST--------KPTNDSY 576
P V+T+HLK F +G L K+N + P L L + T + T Y
Sbjct: 690 PPVLTLHLKRFQQAGF-------NLRKVNKHIKFPEILDLAPFCTLKCKNVAEENTRVLY 742
Query: 577 GLFAVVMHSGITISSGHYTASVKVTDLNS 605
L+ VV HSG T+ SGHYTA K NS
Sbjct: 743 SLYGVVEHSG-TMRSGHYTAYAKARTANS 770
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 78.6 bits (192), Expect = 2e-14
Identities = 154/662 (23%), Positives = 249/662 (37%), Gaps = 156/662 (23%)
Query: 44 ENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCP 103
E E K + R + + A ++ P+N + + GL+NLGNTC+ N+++Q L P
Sbjct: 164 EKESKNEQEREKKENM---AKENPPMNSPCQ---ITVKGLSNLGNTCFFNAVMQNLSQTP 217
Query: 104 GFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQ----- 158
+ E LK+ + LA E L I++E
Sbjct: 218 VLR--------------ELLKEVKMSGTIVKIEPPDLALTE------PLEINLEPPGPLT 257
Query: 159 LQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQ-ETCQL 217
L S LN + T + P+ L + + + ++GY Q D+QE+L+ +L ++ E Q
Sbjct: 258 LAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDSQELLRYLLDGMRAEEHQR 317
Query: 218 LKK--------------EEVKNVAELPTKVEEIPHPKEEMNG---INSIEMDSMR----- 255
+ K EE+KN + K + +P + + G + I D R
Sbjct: 318 VSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSFVDRIFGGELTSMIMCDQCRTVSLV 377
Query: 256 HSEDFKEKLP---KGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQTRSKRKATSDTLE 312
H LP +GK+ + + N+KK V+ E Q EE ++ S K SD
Sbjct: 378 HESFLDLSLPVLDDQSGKKSVNDK--NLKKTVE--DEDQDSEE-EKDNDSYIKERSDIPS 432
Query: 313 SPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGKITTNQGVKGQSK 372
K + K ++ + ++K++ K+ +Q I K L I T +
Sbjct: 433 GTSKHLQK-----KAKKQAKKQA-------KNQRRQQKIQGKVLHLNDICTIDHPEDSEY 480
Query: 373 ENECDPEEDL----------GKCESDNTTNGCGLESPGNTVTPVNVNEVKPINKGEEQIG 422
E E + ++ G + N L + V N+ K E++
Sbjct: 481 EAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQ-----KSTEEVD 535
Query: 423 FELVEKLFQGQLVLR--TRCLECESLTERREDFQDIS---------VPVQEDELS----- 466
+ + +++ TR L LTE DIS + DE++
Sbjct: 536 MKNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDEINIEILN 595
Query: 467 -------KVEESSEISPEP-----------KTEMKTLRWAISQFASVERIVGEDKYFCEN 508
KV E PE T+ +++ + QF E++ +K CE
Sbjct: 596 DSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLCEV 655
Query: 509 C-----------------HHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSK 551
C H YT A++ +L P V+T+HLK F +G L K
Sbjct: 656 CTRRQCNGPKANIKGERKHVYTNAKKQMLISLAPPVLTLHLKRFQQAGF-------NLRK 708
Query: 552 INTPLLTPLKLSLEEWST--------KPTNDSYGLFAVVMHSGITISSGHYTASVKVTDL 603
+N + P L L + T + T Y L+ VV HSG T+ SGHYTA K
Sbjct: 709 VNKHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSG-TMRSGHYTAYAKARTA 767
Query: 604 NS 605
NS
Sbjct: 768 NS 769
Score = 38.5 bits (88), Expect = 0.024
Identities = 58/276 (21%), Positives = 105/276 (38%), Gaps = 28/276 (10%)
Query: 216 QLLKKEEVKNVAELPTKVEEIPHPKEEMNGIN------SIEMDSMRHSE-DFKEKLPKGN 268
Q ++ V + K I PK E + N +E +S E + KE + K N
Sbjct: 124 QYCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENMAKEN 183
Query: 269 GKRKSDTEF-----GNMKKKVKLSKEHQSLEEN----QRQTRSKRKATSDTLESPPKIIP 319
S + N+ + Q+L + + K T +E P +
Sbjct: 184 PPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPDLALT 243
Query: 320 KYISEN-ESPRPSQKKSRVKINWLKSATK----QPSILSKFCSLGKITTNQGVKGQSKEN 374
+ + N E P P +N ++ K + S+ C K +G + Q +
Sbjct: 244 EPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCK--KAVRFKGYQQQDSQE 301
Query: 375 ECDPEEDLGKCESDNTTNGCGLESPGNTVTPVNV---NEVKPINKGEEQIGFELVEKLFQ 431
D + E + L++ GN+ ++ N+VK K + F V+++F
Sbjct: 302 LLRYLLDGMRAEEHQRVSKGILKAFGNSTEKLDEELKNKVKDYEKKKSMPSF--VDRIFG 359
Query: 432 GQLVLRTRCLECESLTERREDFQDISVPVQEDELSK 467
G+L C +C +++ E F D+S+PV +D+ K
Sbjct: 360 GELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGK 395
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 67.8 bits (164), Expect = 4e-11
Identities = 49/178 (27%), Positives = 84/178 (47%), Gaps = 18/178 (10%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
+V +F G L CL C + + + + F D+S+ + SK ++ E P + +
Sbjct: 309 VVTAIFGGILQNEVNCLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGP-----VCS 363
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
LR + F +E + + Y C C ++ + K+P+V+ +HLK F +
Sbjct: 364 LRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRF-----HWTA 418
Query: 545 YGGGLSKINTPLLTPLK------LSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTA 596
Y +K++T + PL+ LE ++ P + Y L AVV+H G + SGHYTA
Sbjct: 419 Y--LRNKVDTYVEFPLRGLDMKCYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTA 474
Score = 39.3 bits (90), Expect = 0.014
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 21/132 (15%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRK-KEALKDEANQKDKGNCKEDSL 140
GL NLGNTC++N+ILQ L F K L + R K A + + + +G+ +
Sbjct: 160 GLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNVSLV 219
Query: 141 ASY-ELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHD 199
+ + +C+L + A P L + ++ P + GY Q D
Sbjct: 220 EEFRKTLCALWQ-------------------GSQTAFSPESLFYVVWKIMPNFRGYQQQD 260
Query: 200 AQEVLQCILGNI 211
A E ++ +L ++
Sbjct: 261 AHEFMRYLLDHL 272
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 28/184 (15%)
Query: 419 EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEP 478
+Q+ ++ LFQGQ +CL C + E F +S+P+
Sbjct: 915 KQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLAS---------------- 958
Query: 479 KTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAAS 538
T TL+ + F+ E++ ++++C +C ++ + + K+P V+ +HLK F+
Sbjct: 959 -TSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYD 1017
Query: 539 GLEFDCYGGGLSKINTPLLTPLK-LSLEEWSTKPTND--SYGLFAVVMHSGITISSGHYT 595
G K+ T + PL+ L L ++ P N+ Y LF+V H G + GHYT
Sbjct: 1018 -------GRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGGHYT 1069
Query: 596 ASVK 599
A K
Sbjct: 1070 AYCK 1073
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 28/184 (15%)
Query: 30 KKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNT 89
++E KR T + E K + Y +EI ++ A+Q +N + GL NLGNT
Sbjct: 727 QEEEKRKPTVTPTVNRENKPTCYPKAEISRL-SASQIRNLNPVFGGSGPALTGLRNLGNT 785
Query: 90 CYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSL 149
CY+NSILQ L P HL + +R NC +D + L+
Sbjct: 786 CYMNSILQCLCNAP-------HLADYFNR---------------NCYQDDINRSNLLGHK 823
Query: 150 QSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILG 209
+ + + +Y P+ T+ ++N + GY Q D+QE+L ++
Sbjct: 824 GEVAEEFGIIMKALWTGQYRY-----ISPKDFKITIGKINDQFAGYSQQDSQELLLFLMD 878
Query: 210 NIQE 213
+ E
Sbjct: 879 GLHE 882
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 28/184 (15%)
Query: 419 EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEP 478
+Q+ ++ LFQGQ +CL C + E F +S+P+
Sbjct: 915 KQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLAS---------------- 958
Query: 479 KTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAAS 538
T TL+ + F+ E++ ++++C +C ++ + + K+P V+ +HLK F+
Sbjct: 959 -TSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYD 1017
Query: 539 GLEFDCYGGGLSKINTPLLTPLK-LSLEEWSTKPTND--SYGLFAVVMHSGITISSGHYT 595
G K+ T + PL+ L L ++ P N+ Y LF+V H G + GHYT
Sbjct: 1018 -------GRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGGHYT 1069
Query: 596 ASVK 599
A K
Sbjct: 1070 AYCK 1073
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 28/184 (15%)
Query: 30 KKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNT 89
++E KR T + E K + Y +EI ++ A+Q +N + GL NLGNT
Sbjct: 727 QEEEKRKPTVTPTVNRENKPTCYPKAEISRL-SASQIRNLNPVFGGSGPALTGLRNLGNT 785
Query: 90 CYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSL 149
CY+NSILQ L P HL + +R NC +D + L+
Sbjct: 786 CYMNSILQCLCNAP-------HLADYFNR---------------NCYQDDINRSNLLGHK 823
Query: 150 QSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILG 209
+ + + +Y P+ T+ ++N + GY Q D+QE+L ++
Sbjct: 824 GEVAEEFGIIMKALWTGQYRY-----ISPKDFKITIGKINDQFAGYSQQDSQELLLFLMD 878
Query: 210 NIQE 213
+ E
Sbjct: 879 GLHE 882
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 66.6 bits (161), Expect = 8e-11
Identities = 48/184 (26%), Positives = 83/184 (45%), Gaps = 28/184 (15%)
Query: 419 EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEP 478
+Q+ ++ LFQGQ +CL C + E F +S+P+
Sbjct: 915 KQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLAS---------------- 958
Query: 479 KTEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAAS 538
T TL+ + F+ E++ ++++C +C ++ + + K+P V+ +HLK F+
Sbjct: 959 -TSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYD 1017
Query: 539 GLEFDCYGGGLSKINTPLLTPLK-LSLEEWSTKPTND--SYGLFAVVMHSGITISSGHYT 595
G K+ T + PL+ L L ++ P N+ Y LF+V H G + GHYT
Sbjct: 1018 -------GRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYG-GLDGGHYT 1069
Query: 596 ASVK 599
A K
Sbjct: 1070 AYCK 1073
Score = 53.5 bits (127), Expect = 7e-07
Identities = 47/184 (25%), Positives = 77/184 (41%), Gaps = 28/184 (15%)
Query: 30 KKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNT 89
++E KR T + E K + Y +EI ++ A+Q +N + GL NLGNT
Sbjct: 727 QEEEKRKPTVTPTVNRENKPTCYPKAEISRL-SASQIRNLNPVFGGSGPALTGLRNLGNT 785
Query: 90 CYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSL 149
CY+NSILQ L P HL + +R NC +D + L+
Sbjct: 786 CYMNSILQCLCNAP-------HLADYFNR---------------NCYQDDINRSNLLGHK 823
Query: 150 QSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQEVLQCILG 209
+ + + +Y P+ T+ ++N + GY Q D+QE+L ++
Sbjct: 824 GEVAEEFGIIMKALWTGQYRY-----ISPKDFKITIGKINDQFAGYSQQDSQELLLFLMD 878
Query: 210 NIQE 213
+ E
Sbjct: 879 GLHE 882
>gi|79750944 ubiquitin specific peptidase 42 [Homo sapiens]
Length = 1316
Score = 66.2 bits (160), Expect = 1e-10
Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 30/180 (16%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
LV ++F G L R +CL C+ +++ + + DI++ ++ + +
Sbjct: 229 LVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQ-------------------S 269
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
+ A+ QF E++ GE+ Y C C A + + V+T+ LK FA
Sbjct: 270 VNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFAN------- 322
Query: 545 YGGGLSKINTPLLTPLKLSLEEWSTKPTNDS--YGLFAVVMHSGITISSGHYTASVKVTD 602
+ GG KI + P L + + ++P + Y L+AV++H+G +GHY +K ++
Sbjct: 323 FTGG--KIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASN 380
Score = 35.8 bits (81), Expect = 0.16
Identities = 35/134 (26%), Positives = 56/134 (41%), Gaps = 32/134 (23%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
GL NLGNTC+ N+ LQ L + P L N + + + A +G C
Sbjct: 112 GLQNLGNTCFANAALQCLTYTP-------PLANYMLSHEHSKTCHA----EGFC------ 154
Query: 142 SYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQ 201
++C++Q+ I L NP +P ++N +R + + Q DA
Sbjct: 155 ---MMCTMQAHITQA-------LSNPGD-----VIKPMFVINEMRRIARHFRFGNQEDAH 199
Query: 202 EVLQCILGNIQETC 215
E LQ + +Q+ C
Sbjct: 200 EFLQYTVDAMQKAC 213
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 65.9 bits (159), Expect = 1e-10
Identities = 56/192 (29%), Positives = 87/192 (45%), Gaps = 36/192 (18%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEP--KTEM 482
+V +F GQL+ + CL C++ + E F D+S+ E +I+ +P TEM
Sbjct: 464 VVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS---GKDIASQPCLVTEM 520
Query: 483 KTLRWAISQFASVERIVGEDKYFCENCHH-----------YTEAERSLLFDKMPEVITIH 531
+++F E + G+ Y C+ C+ TEA++ L+ +P+V+ +H
Sbjct: 521 ------LAKFTETEALEGKI-YVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLH 573
Query: 532 LKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMH 584
LK F SG KI + L++E + + T S Y L AVVMH
Sbjct: 574 LKRFRWSGRN------NREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMH 627
Query: 585 SGITISSGHYTA 596
G SGHYTA
Sbjct: 628 HGKGFGSGHYTA 639
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/254 (25%), Positives = 103/254 (40%), Gaps = 65/254 (25%)
Query: 40 TDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFV-GLNNLGNTCYLNSILQV 98
T + ++K +EI Q V S + ++R + P V GL NLGNTCY+NS+LQV
Sbjct: 236 TPASPAKDKVLSTSENEISQKV-----SDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQV 290
Query: 99 LYFCPGFKSGV------KHLFNIISRKKEALK------------DEANQKDKGNCKEDSL 140
L F+ + L S K + K +E +KD G
Sbjct: 291 LSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTG------- 343
Query: 141 ASYELICSLQSLIIS-----VEQLQASFLLNPEKYTDELAT------------------- 176
+CS QS + S + + L+ P++ T + +
Sbjct: 344 ----FVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWAL 399
Query: 177 -QPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEE 235
P +L+++ L P + GY Q DAQE L +L IQ L+ A +PT +
Sbjct: 400 VSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---LETTGTSLPALIPTSQRK 456
Query: 236 IPHPKEEMNGINSI 249
+ K+ +N +N+I
Sbjct: 457 L--IKQVLNVVNNI 468
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 65.9 bits (159), Expect = 1e-10
Identities = 56/192 (29%), Positives = 87/192 (45%), Gaps = 36/192 (18%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEP--KTEM 482
+V +F GQL+ + CL C++ + E F D+S+ E +I+ +P TEM
Sbjct: 464 VVNNIFHGQLLSQVTCLACDNKSNTIEPFWDLSLEFPERYQCS---GKDIASQPCLVTEM 520
Query: 483 KTLRWAISQFASVERIVGEDKYFCENCHH-----------YTEAERSLLFDKMPEVITIH 531
+++F E + G+ Y C+ C+ TEA++ L+ +P+V+ +H
Sbjct: 521 ------LAKFTETEALEGKI-YVCDQCNSKRRRFSSKPVVLTEAQKQLMICHLPQVLRLH 573
Query: 532 LKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMH 584
LK F SG KI + L++E + + T S Y L AVVMH
Sbjct: 574 LKRFRWSGRN------NREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLSAVVMH 627
Query: 585 SGITISSGHYTA 596
G SGHYTA
Sbjct: 628 HGKGFGSGHYTA 639
Score = 49.3 bits (116), Expect = 1e-05
Identities = 65/254 (25%), Positives = 103/254 (40%), Gaps = 65/254 (25%)
Query: 40 TDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFV-GLNNLGNTCYLNSILQV 98
T + ++K +EI Q V S + ++R + P V GL NLGNTCY+NS+LQV
Sbjct: 236 TPASPAKDKVLSTSENEISQKV-----SDSSVKRRPIVTPGVTGLRNLGNTCYMNSVLQV 290
Query: 99 LYFCPGFKSGV------KHLFNIISRKKEALK------------DEANQKDKGNCKEDSL 140
L F+ + L S K + K +E +KD G
Sbjct: 291 LSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVVYQMNECQEKDTG------- 343
Query: 141 ASYELICSLQSLIIS-----VEQLQASFLLNPEKYTDELAT------------------- 176
+CS QS + S + + L+ P++ T + +
Sbjct: 344 ----FVCSRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLFQVMWSGKWAL 399
Query: 177 -QPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEE 235
P +L+++ L P + GY Q DAQE L +L IQ L+ A +PT +
Sbjct: 400 VSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---LETTGTSLPALIPTSQRK 456
Query: 236 IPHPKEEMNGINSI 249
+ K+ +N +N+I
Sbjct: 457 L--IKQVLNVVNNI 468
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 65.1 bits (157), Expect = 2e-10
Identities = 44/180 (24%), Positives = 82/180 (45%), Gaps = 30/180 (16%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
LV ++F G L R +C C+S+++ + + D+++ +++
Sbjct: 240 LVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQ-------------------AAN 280
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
+ A+ F + + GE+ Y C C A + + V+T+ LK FA
Sbjct: 281 IVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFAN------- 333
Query: 545 YGGGLSKINTPLLTPLKLSLEEWSTKPTNDS--YGLFAVVMHSGITISSGHYTASVKVTD 602
+ GG KI + P L++ + ++ D YGL+AV++HSG + +GHY VK ++
Sbjct: 334 FSGG--KITKDVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASN 391
Score = 37.4 bits (85), Expect = 0.054
Identities = 32/134 (23%), Positives = 58/134 (43%), Gaps = 32/134 (23%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
GL+NLGNTC+LN+ +Q L + P L N + K+ A +C +
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTP-------PLANYLLSKEHA----------RSCHQ---G 162
Query: 142 SYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQ 201
S+ ++C +Q+ I+ + A +P + L+++ + Q DA
Sbjct: 163 SFCMLCVMQNHIVQAFANSGN------------AIKPVSFIRDLKKIARHFRFGNQEDAH 210
Query: 202 EVLQCILGNIQETC 215
E L+ + +Q+ C
Sbjct: 211 EFLRYTIDAMQKAC 224
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 65.1 bits (157), Expect = 2e-10
Identities = 54/198 (27%), Positives = 84/198 (42%), Gaps = 31/198 (15%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDE-----LSKVEESSEISPEPK 479
+++++F G L C C ++ + F DIS+ + LS E + ++ E
Sbjct: 296 IIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGSSTPFWPLSPGSEGNVVNGESH 355
Query: 480 TE-MKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAAS 538
TL + +F E + K C CH Y E+ + L K+P V HLK F S
Sbjct: 356 VSGTTTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRFEHS 415
Query: 539 GLEFDCYGGGLSKINTPLLTPLKLSLEEWST------------KPT-----NDSYGLFAV 581
KI T + PL+L + + +PT ++ Y LFAV
Sbjct: 416 AKL-------RRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDNKYSLFAV 468
Query: 582 VMHSGITISSGHYTASVK 599
V H G T+ SGHYT+ ++
Sbjct: 469 VNHQG-TLESGHYTSFIR 485
Score = 34.3 bits (77), Expect = 0.46
Identities = 36/136 (26%), Positives = 52/136 (38%), Gaps = 34/136 (25%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
GL NLGNTC++N I+Q L P L + D+ C+ S +
Sbjct: 177 GLINLGNTCFMNCIVQALTHTP-------------------LLRDFFLSDRHRCEMQSPS 217
Query: 142 SYELICSLQSLIISVEQLQASFLLNPEKYTDELATQ-PRRLLNTLRELNPMYEGYLQHDA 200
S L+C + SL E Y+ + P +LL+ + GY Q DA
Sbjct: 218 SC-LVCEMSSLF-------------QEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDA 263
Query: 201 QEVLQCILGNIQETCQ 216
E L L + C+
Sbjct: 264 HEFLIAALDVLHRHCK 279
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 65.1 bits (157), Expect = 2e-10
Identities = 53/197 (26%), Positives = 85/197 (43%), Gaps = 30/197 (15%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQE-----DELSKVEESSEISPEPK 479
+++++F G L C C S++ + DIS+ + D + S +S +
Sbjct: 483 IIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRDDH 542
Query: 480 TE-MKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAAS 538
+ +L + F E + K C +C Y E+ + L K+P V HLK
Sbjct: 543 IPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLK----- 597
Query: 539 GLEFDCYGGGLSKINTPLLTPLKLSLEEW--STK--------------PTNDSYGLFAVV 582
F+ G KINT + PL+L + + STK P + Y LFAV+
Sbjct: 598 --RFEHVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVI 655
Query: 583 MHSGITISSGHYTASVK 599
H G T+ SGHYT+ ++
Sbjct: 656 NHHG-TLESGHYTSFIR 671
Score = 32.0 bits (71), Expect = 2.3
Identities = 14/25 (56%), Positives = 17/25 (68%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFK 106
GL NLGNTC++N I+Q L P K
Sbjct: 364 GLINLGNTCFMNCIVQALTHIPLLK 388
>gi|76257392 ubiquitin specific protease 48 isoform b [Homo sapiens]
Length = 485
Score = 64.3 bits (155), Expect = 4e-10
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 25/176 (14%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
+V++ F G+ T C +C ++ F ++ + +Q K
Sbjct: 208 IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGH-------------------KQ 248
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
L IS+F E++ G+++YFCENC A R + +P + + L F FD
Sbjct: 249 LTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFV-----FDR 303
Query: 545 YGGGLSKINTPLLTPLKLSLEEW-STKPTNDSYGLFAVVMHSGITISSGHYTASVK 599
G K+NT + L +E + K + Y L AV++H G++ SGHY A VK
Sbjct: 304 QTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVK 359
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/171 (23%), Positives = 66/171 (38%), Gaps = 51/171 (29%)
Query: 70 NCEKRENLLPFVGLNNLGNTCYLNSILQV----------LYFCPGFKSGVKHLFNIISRK 119
NCE+R+ FVGL NLG TCY+N+ LQV LY CP S
Sbjct: 79 NCERRKKN-SFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCP-------------STC 124
Query: 120 KEALKDEANQKDKGNCKEDSLASYE--LICSLQSLIISVEQLQASFLLNPEKYTDELATQ 177
+ + + Q++K YE IC + ++ Q ++P + L
Sbjct: 125 SDYMLGDGIQEEK---------DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLD 175
Query: 178 PRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAE 228
+ Q DAQE + + +++T K +V+N+ +
Sbjct: 176 TGQ----------------QQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQ 210
>gi|52630449 ubiquitin specific protease 48 isoform a [Homo sapiens]
Length = 1035
Score = 64.3 bits (155), Expect = 4e-10
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 25/176 (14%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
+V++ F G+ T C +C ++ F ++ + +Q K
Sbjct: 208 IVQQQFCGEYAYVTVCNQCGRESKLLSKFYELELNIQGH-------------------KQ 248
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
L IS+F E++ G+++YFCENC A R + +P + + L F FD
Sbjct: 249 LTDCISEFLKEEKLEGDNRYFCENCQSKQNATRKIRLLSLPCTLNLQLMRFV-----FDR 303
Query: 545 YGGGLSKINTPLLTPLKLSLEEW-STKPTNDSYGLFAVVMHSGITISSGHYTASVK 599
G K+NT + L +E + K + Y L AV++H G++ SGHY A VK
Sbjct: 304 QTGHKKKLNTYIGFSEILDMEPYVEHKGGSYVYELSAVLIHRGVSAYSGHYIAHVK 359
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/171 (23%), Positives = 66/171 (38%), Gaps = 51/171 (29%)
Query: 70 NCEKRENLLPFVGLNNLGNTCYLNSILQV----------LYFCPGFKSGVKHLFNIISRK 119
NCE+R+ FVGL NLG TCY+N+ LQV LY CP S
Sbjct: 79 NCERRKKN-SFVGLTNLGATCYVNTFLQVWFLNLELRQALYLCP-------------STC 124
Query: 120 KEALKDEANQKDKGNCKEDSLASYE--LICSLQSLIISVEQLQASFLLNPEKYTDELATQ 177
+ + + Q++K YE IC + ++ Q ++P + L
Sbjct: 125 SDYMLGDGIQEEK---------DYEPQTICEHLQYLFALLQNSNRRYIDPSGFVKALGLD 175
Query: 178 PRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQLLKKEEVKNVAE 228
+ Q DAQE + + +++T K +V+N+ +
Sbjct: 176 TGQ----------------QQDAQEFSKLFMSLLEDTLSKQKNPDVRNIVQ 210
>gi|41055953 ubiquitin thioesterase 40 [Homo sapiens]
Length = 1247
Score = 63.9 bits (154), Expect = 5e-10
Identities = 86/379 (22%), Positives = 159/379 (41%), Gaps = 67/379 (17%)
Query: 422 GFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTE 481
G +L+ +L+ G +V + C EC++++ER+EDF D++V V+ +S +E++
Sbjct: 166 GHDLIYRLYHGTIVNQIVCKECKNVSERQEDFLDLTVAVK--NVSGLEDA---------- 213
Query: 482 MKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLE 541
W + + E ++ Y C C +A +S K+P +T+ L F ++
Sbjct: 214 ----LW--NMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVK 267
Query: 542 FDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS----YGLFAVVMHSGITISSGHYTAS 597
+ Y K + PL+++L+ + + D Y LF+V++H G GHY
Sbjct: 268 CERY-----KETSCYTFPLRINLKPFCEQSELDDLEYIYDLFSVIIHKG-GCYGGHYHVY 321
Query: 598 VKVTDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVG-----GNT 652
+K D GN+ + E KP+ +N ++ + E D + I N
Sbjct: 322 IKDVD------HLGNWQFQE--EKSKPD-VNLKDLQS--EEEIDHPLMILKAILLEENNL 370
Query: 653 QPSKVLNKKNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRNSETSD--TTGTH 710
P L +K ++ IG+ +K + + K ++ S F + + T +
Sbjct: 371 IPVDQLGQKLLKKIGISWNKKYRKQHGPLRKFL---QLHSQIFLLSSDESTVRLLKNSSL 427
Query: 711 ESDRNKESSDQTGINI-----SGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLN 765
+++ + + +DQ + G N IS W +DS+V+ EKD
Sbjct: 428 QAESDFQRNDQQIFKMLPPESPGLNNSISC---------PHWFDINDSKVQPIREKDIEQ 478
Query: 766 SLSPSTSPTSTPYLLFYKK 784
S Y+LFY+K
Sbjct: 479 QFQGKES----AYMLFYRK 493
Score = 39.3 bits (90), Expect = 0.014
Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 7/55 (12%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCK 136
G+ N G TCYLNS+LQ L+F P F+ LF++ + +D KDK + K
Sbjct: 54 GIRNQGGTCYLNSLLQTLHFTPEFREA---LFSLGPEELGLFED----KDKPDAK 101
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 63.2 bits (152), Expect = 9e-10
Identities = 58/216 (26%), Positives = 95/216 (43%), Gaps = 37/216 (17%)
Query: 395 GLESPGNTVT------PVNVNEVKPINKGEEQIGFEL------VEKLFQGQLVLRTRCLE 442
GL + N VT P N++ + KG + L + LF GQL C +
Sbjct: 159 GLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTD 218
Query: 443 CESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGED 502
C + + F D+S+P+ + +V TL + F + + G++
Sbjct: 219 CGYCSTVFDPFWDLSLPIAKRGYPEV---------------TLMDCMRLFTKEDVLDGDE 263
Query: 503 KYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLK- 561
K C C + + P+++ +HLK F+ S + SK+ T + PL+
Sbjct: 264 KPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIR-------TSKLTTFVNFPLRD 316
Query: 562 LSLEEWSTKPTNDS-YGLFAVVMHSGITISSGHYTA 596
L L E++++ TN + Y L+AV HSG T+ GHYTA
Sbjct: 317 LDLREFASENTNHAVYNLYAVSNHSGTTM-GGHYTA 351
Score = 40.0 bits (92), Expect = 0.008
Identities = 40/153 (26%), Positives = 64/153 (41%), Gaps = 33/153 (21%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQK-DKGNCKEDSL 140
GL NLGNTC++NSILQ L S +E L+D Q+ + S
Sbjct: 59 GLRNLGNTCFMNSILQCL-----------------SNTRE-LRDYCLQRLYMRDLHHGSN 100
Query: 141 ASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDA 200
A L+ LI ++ + +++P ++ + ++ P + GY Q DA
Sbjct: 101 AHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQ-----------IQRYAPRFVGYNQQDA 149
Query: 201 QEVLQCILGNIQETCQ---LLKKEEVKNVAELP 230
QE L+ +L + L K +N+ LP
Sbjct: 150 QEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLP 182
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 63.2 bits (152), Expect = 9e-10
Identities = 58/216 (26%), Positives = 95/216 (43%), Gaps = 37/216 (17%)
Query: 395 GLESPGNTVT------PVNVNEVKPINKGEEQIGFEL------VEKLFQGQLVLRTRCLE 442
GL + N VT P N++ + KG + L + LF GQL C +
Sbjct: 368 GLHNEVNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSRIGDLFVGQLKSSLTCTD 427
Query: 443 CESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVGED 502
C + + F D+S+P+ + +V TL + F + + G++
Sbjct: 428 CGYCSTVFDPFWDLSLPIAKRGYPEV---------------TLMDCMRLFTKEDVLDGDE 472
Query: 503 KYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLK- 561
K C C + + P+++ +HLK F+ S + SK+ T + PL+
Sbjct: 473 KPTCCRCRGRKRCIKKFSIQRFPKILVLHLKRFSESRIR-------TSKLTTFVNFPLRD 525
Query: 562 LSLEEWSTKPTNDS-YGLFAVVMHSGITISSGHYTA 596
L L E++++ TN + Y L+AV HSG T+ GHYTA
Sbjct: 526 LDLREFASENTNHAVYNLYAVSNHSGTTM-GGHYTA 560
Score = 42.0 bits (97), Expect = 0.002
Identities = 46/177 (25%), Positives = 74/177 (41%), Gaps = 40/177 (22%)
Query: 62 PAAQSSP----INCEKRENLLPFVGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIIS 117
P+ SSP +N + + L GL NLGNTC++NSILQ L S
Sbjct: 247 PSRSSSPGRDGMNSKSAQGL---AGLRNLGNTCFMNSILQCL-----------------S 286
Query: 118 RKKEALKDEANQK-DKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELAT 176
+E L+D Q+ + S A L+ LI ++ + +++P ++ +
Sbjct: 287 NTRE-LRDYCLQRLYMRDLHHGSNAHTALVEEFAKLIQTIWTSSPNDVVSPSEFKTQ--- 342
Query: 177 QPRRLLNTLRELNPMYEGYLQHDAQEVLQCILGNIQETCQ---LLKKEEVKNVAELP 230
++ P + GY Q DAQE L+ +L + L K +N+ LP
Sbjct: 343 --------IQRYAPRFVGYNQQDAQEFLRFLLDGLHNEVNRVTLRPKSNPENLDHLP 391
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 62.8 bits (151), Expect = 1e-09
Identities = 52/197 (26%), Positives = 82/197 (41%), Gaps = 30/197 (15%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQED-----ELSKVEESSEISPEPK 479
+++++F G L C C ++ + DIS+ + +S ESS
Sbjct: 198 IIDQIFTGGLQSDVTCQACHGVSTTIDPCWDISLDLPGSCTSFWPMSPGRESSVNGESHI 257
Query: 480 TEMKTLRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASG 539
+ TL + +F E + K C +C Y E+ + L +K+P V H K F S
Sbjct: 258 PGITTLTDCLRRFTRPEHLGSSAKIKCGSCQSYQESTKQLTMNKLPVVACFHFKRFEHSA 317
Query: 540 LEFDCYGGGLSKINTPLLTPLKLSLEEWSTK------------PTN-----DSYGLFAVV 582
+ KI T + PL+L + + PTN + Y LFAVV
Sbjct: 318 KQ-------RRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNENKYSLFAVV 370
Query: 583 MHSGITISSGHYTASVK 599
H G T+ SGHYT+ ++
Sbjct: 371 NHQG-TLESGHYTSFIR 386
Score = 33.1 bits (74), Expect = 1.0
Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 35/149 (23%)
Query: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
GL NLGNTC++N I+Q L P + + D+ C+ S
Sbjct: 79 GLINLGNTCFMNCIVQALTHTP-------------------ILRDFFLSDRHRCEMPS-P 118
Query: 142 SYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDAQ 201
L+C + SL + + NP + P +LL+ + GY Q DA
Sbjct: 119 ELCLVCEMSSL------FRELYSGNPSPHV------PYKLLHLVWIHARHLAGYRQQDAH 166
Query: 202 EVLQCILGNIQETCQLLKKEEVKNVAELP 230
E L L + C K ++V A P
Sbjct: 167 EFLIAALDVLHRHC---KGDDVGKAANNP 192
>gi|21361749 ubiquitin thioesterase 49 [Homo sapiens]
Length = 640
Score = 61.2 bits (147), Expect = 4e-09
Identities = 53/191 (27%), Positives = 85/191 (44%), Gaps = 29/191 (15%)
Query: 424 ELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMK 483
++V +F GQL+ + C+ C + E F D+S+ E +E+ P +TE
Sbjct: 439 KVVNTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPE-RYHCIEKG--FVPLNQTEC- 494
Query: 484 TLRWAISQFASVERIVGEDKYFCENCHH-----------YTEAERSLLFDKMPEVITIHL 532
L +++F E + G Y C+ C+ +EA + L+ ++P+V+ +HL
Sbjct: 495 LLTEMLAKFTETEALEGRI-YACDQCNSKRRKSNPKPLVLSEARKQLMIYRLPQVLRLHL 553
Query: 533 KCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMHS 585
K F SG KI ++ L++E + + S Y L AVVMH
Sbjct: 554 KRFRWSGRNHR------EKIGVHVVFDQVLTMEPYCCRDMLSSLDKETFAYDLSAVVMHH 607
Query: 586 GITISSGHYTA 596
G SGHYTA
Sbjct: 608 GKGFGSGHYTA 618
Score = 48.9 bits (115), Expect = 2e-05
Identities = 60/224 (26%), Positives = 94/224 (41%), Gaps = 42/224 (18%)
Query: 49 ASEYRASEIDQVVPAAQSSPINCEKRENLLPFV-GLNNLGNTCYLNSILQVLYFCPGFK- 106
AS A + VPAA + ++ + P V GL NLGNTCY+NSILQVL F+
Sbjct: 223 ASRPAALPTSRRVPAAT---LKLRRQPAMAPGVTGLRNLGNTCYMNSILQVLSHLQKFRE 279
Query: 107 -------SGVKHLFNIISRKKEALKDEAN---------QKDKGN-CKEDSLA-------- 141
S +HLF + K L + + D+ C+ +
Sbjct: 280 CFLNLDPSKTEHLFPKATNGKTQLSGKPTNSSATELSLRNDRAEACEREGFCWNGRASIS 339
Query: 142 -SYELICSLQSLIISVEQLQASFLLNPEKYTDELA-TQPRRLLNTLRELNPMYEGYLQHD 199
S ELI + + + + L ++ + A P +L+++ L P + GY Q D
Sbjct: 340 RSLELIQNKEPSSKHISLCRELHTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQD 399
Query: 200 AQEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPKEEM 243
AQE L C+LL K + + +E T+ IP + ++
Sbjct: 400 AQEFL----------CELLHKVQQELESEGTTRRILIPFSQRKL 433
>gi|62243586 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 60.1 bits (144), Expect = 8e-09
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 23/170 (13%)
Query: 429 LFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWA 488
LF GQL +C C + E F D+S+P+ + + + S LR
Sbjct: 373 LFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVS-------------LRDC 419
Query: 489 ISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGG 548
+ F E + E+ C+ C T + + L + P ++ +HL F+AS G
Sbjct: 420 FNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-------RGS 472
Query: 549 LSKINTPLLTPL-KLSLEEW-STKPTNDSYGLFAVVMHSGITISSGHYTA 596
+ K + + PL +LSL ++ S K + Y L+A+ HSG ++ GHYTA
Sbjct: 473 IKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSG-SVHYGHYTA 521
Score = 38.9 bits (89), Expect = 0.019
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 29/128 (22%)
Query: 81 VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSL 140
VGL NLGNTC+LN++LQ L S + L + L+ + Q+ G +
Sbjct: 212 VGLRNLGNTCFLNAVLQCL-------SSTRPL------RDFCLRRDFRQEVPGGGR---- 254
Query: 141 ASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDA 200
+ EL + +I L +P+ A P R ++ P + GY Q DA
Sbjct: 255 -AQELTEAFADVI--------GALWHPDSCE---AVNPTRFRAVFQKYVPSFSGYSQQDA 302
Query: 201 QEVLQCIL 208
QE L+ ++
Sbjct: 303 QEFLKLLM 310
>gi|74027267 ubiquitin-specific protease 21 [Homo sapiens]
Length = 565
Score = 60.1 bits (144), Expect = 8e-09
Identities = 48/170 (28%), Positives = 78/170 (45%), Gaps = 23/170 (13%)
Query: 429 LFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWA 488
LF GQL +C C + E F D+S+P+ + + + S LR
Sbjct: 373 LFVGQLKSCLKCQACGYRSTTFEVFCDLSLPIPKKGFAGGKVS-------------LRDC 419
Query: 489 ISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGG 548
+ F E + E+ C+ C T + + L + P ++ +HL F+AS G
Sbjct: 420 FNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRFSAS-------RGS 472
Query: 549 LSKINTPLLTPL-KLSLEEW-STKPTNDSYGLFAVVMHSGITISSGHYTA 596
+ K + + PL +LSL ++ S K + Y L+A+ HSG ++ GHYTA
Sbjct: 473 IKKSSVGVDFPLQRLSLGDFASDKAGSPVYQLYALCNHSG-SVHYGHYTA 521
Score = 38.9 bits (89), Expect = 0.019
Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 29/128 (22%)
Query: 81 VGLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSL 140
VGL NLGNTC+LN++LQ L S + L + L+ + Q+ G +
Sbjct: 212 VGLRNLGNTCFLNAVLQCL-------SSTRPL------RDFCLRRDFRQEVPGGGR---- 254
Query: 141 ASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDA 200
+ EL + +I L +P+ A P R ++ P + GY Q DA
Sbjct: 255 -AQELTEAFADVI--------GALWHPDSCE---AVNPTRFRAVFQKYVPSFSGYSQQDA 302
Query: 201 QEVLQCIL 208
QE L+ ++
Sbjct: 303 QEFLKLLM 310
>gi|239742285 PREDICTED: hypothetical protein XP_002342486 [Homo
sapiens]
Length = 559
Score = 58.9 bits (141), Expect = 2e-08
Identities = 42/198 (21%), Positives = 87/198 (43%), Gaps = 28/198 (14%)
Query: 425 LVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKT 484
L+ ++F G + +CL C +++ + + DI++ +Q + +
Sbjct: 192 LIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQ-------------------S 232
Query: 485 LRWAISQFASVERIVGEDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDC 544
++ A+ Q E + GE+ Y C C A ++L +V+ + LK F+ D
Sbjct: 233 VQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS------DV 286
Query: 545 YGGGLSK-INTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKVTDL 603
G + K + P +KL + + ++ P Y L+AV++H+G + +GHY + VK +
Sbjct: 287 TGNKIDKNVQYPECLDMKLYMSQTNSGPL--VYVLYAVLVHAGWSCHNGHYFSYVKAQEG 344
Query: 604 NSLELDKGNFVVDQMCEI 621
++D + +
Sbjct: 345 QWYKMDDAEVTASSITSV 362
Score = 36.2 bits (82), Expect = 0.12
Identities = 21/68 (30%), Positives = 29/68 (42%), Gaps = 4/68 (5%)
Query: 40 TDSQENEEKASEYRASEIDQVVPAAQS----SPINCEKRENLLPFVGLNNLGNTCYLNSI 95
T E + E R D + P A+ + R GL N+GNTCY+N+
Sbjct: 35 TSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNAS 94
Query: 96 LQVLYFCP 103
LQ L + P
Sbjct: 95 LQCLTYTP 102
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,947,510
Number of Sequences: 37866
Number of extensions: 1464690
Number of successful extensions: 5727
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 114
Number of HSP's successfully gapped in prelim test: 183
Number of HSP's that attempted gapping in prelim test: 4983
Number of HSP's gapped (non-prelim): 797
length of query: 785
length of database: 18,247,518
effective HSP length: 110
effective length of query: 675
effective length of database: 14,082,258
effective search space: 9505524150
effective search space used: 9505524150
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.