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Search of human proteins with 31377750
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377750 YTH domain family, member 1 [Homo sapiens]
(559 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377750 YTH domain family, member 1 [Homo sapiens] 1163 0.0
gi|116235460 YTH domain family, member 3 [Homo sapiens] 791 0.0
gi|116812575 high glucose-regulated protein 8 [Homo sapiens] 747 0.0
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 74 5e-13
gi|38505213 YTH domain containing 2 [Homo sapiens] 71 2e-12
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 70 4e-12
gi|119943102 CREB binding protein isoform b [Homo sapiens] 50 5e-06
gi|119943104 CREB binding protein isoform a [Homo sapiens] 50 5e-06
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 49 1e-05
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 49 2e-05
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 49 2e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 48 2e-05
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 48 3e-05
gi|55750053 atrophin-1 [Homo sapiens] 47 4e-05
gi|55750041 atrophin-1 [Homo sapiens] 47 4e-05
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 47 4e-05
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 47 4e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 47 5e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 47 6e-05
gi|47132519 Ras association and pleckstrin homology domains 1 is... 47 6e-05
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 45 1e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 45 1e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 45 1e-04
gi|50345881 cytoplasmic polyadenylation element binding protein ... 44 3e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 44 3e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 44 3e-04
gi|190343021 Sec24-related protein D [Homo sapiens] 44 3e-04
gi|221139926 NHS-like 1 [Homo sapiens] 44 4e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 44 5e-04
gi|50345997 E1A binding protein p300 [Homo sapiens] 44 5e-04
>gi|31377750 YTH domain family, member 1 [Homo sapiens]
Length = 559
Score = 1163 bits (3008), Expect = 0.0
Identities = 559/559 (100%), Positives = 559/559 (100%)
Query: 1 MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY 60
MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY
Sbjct: 1 MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY 60
Query: 61 PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRF 120
PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRF
Sbjct: 61 PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRF 120
Query: 121 NFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGM 180
NFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGM
Sbjct: 121 NFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGM 180
Query: 181 NSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASK 240
NSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASK
Sbjct: 181 NSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASK 240
Query: 241 PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQ 300
PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQ
Sbjct: 241 PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQ 300
Query: 301 VAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAP 360
VAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAP
Sbjct: 301 VAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAP 360
Query: 361 SVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKR 420
SVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKR
Sbjct: 361 SVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKR 420
Query: 421 LDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIF 480
LDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIF
Sbjct: 421 LDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIF 480
Query: 481 VKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYE 540
VKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYE
Sbjct: 481 VKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYE 540
Query: 541 KRQEEEEVVRKERQSRNKQ 559
KRQEEEEVVRKERQSRNKQ
Sbjct: 541 KRQEEEEVVRKERQSRNKQ 559
>gi|116235460 YTH domain family, member 3 [Homo sapiens]
Length = 585
Score = 791 bits (2043), Expect = 0.0
Identities = 403/588 (68%), Positives = 459/588 (78%), Gaps = 32/588 (5%)
Query: 1 MSATSVDTQRTKGQDNKV--QNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSS 58
MSATSVD QR KGQ NKV QNGS+HQKD V+D+DFEPYL+ Q+NQSNSYP MSDPY+ S
Sbjct: 1 MSATSVD-QRPKGQGNKVSVQNGSIHQKDAVNDDDFEPYLSSQTNQSNSYPPMSDPYMPS 59
Query: 59 YYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNN---I 115
YY PSIGFPYSL EA WSTAGD P+PYLTTYGQ+SNG+HH++ D VF QPG LGN +
Sbjct: 60 YYAPSIGFPYSLGEAAWSTAGDQPMPYLTTYGQMSNGEHHYIPDGVFSQPGALGNTPPFL 119
Query: 116 YQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLS 175
QH FNFFP N FS WGTSGSQGQ TQSSAY SSY YPPSSLG + DGQ GF +DTLS
Sbjct: 120 GQHGFNFFPGNADFSTWGTSGSQGQSTQSSAYSSSYGYPPSSLGRAITDGQAGFGNDTLS 179
Query: 176 KAPGMNSLEQGMVGLKIG-DVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSW 234
K PG++S+EQGM GLKIG D++++ KTVG+ +SS +T + + N V+ KPTSW
Sbjct: 180 KVPGISSIEQGMTGLKIGGDLTAAVTKTVGTALSSSGMTSIAT-NSVPPVSSAAPKPTSW 238
Query: 235 AAIASKPAKPQPKMKTKSGPVMGGG-LPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQ 293
AAIA KPAKPQPK+K K +GG +PPPPIKHNM+IGTWD KG V KAP Q PQ
Sbjct: 239 AAIARKPAKPQPKLKPKGNVGIGGSAVPPPPIKHNMNIGTWDEKGSVVKAPPTQPVLPPQ 298
Query: 294 AA-PQPQQVAQP-------LPAQPPALAQPQYQSPQQPP-------------QTRWVAPR 332
QPQ + QP LP Q P QPQ Q QP Q RWVAPR
Sbjct: 299 TIIQQPQPLIQPPPLVQSQLPQQQPQPPQPQQQQGPQPQAQPHQVQPQQQQLQNRWVAPR 358
Query: 333 NRNAAFGQSGGAGSDSNSPGNVQPNSAPS-VESHPVLEKLKAAHSYNPKEFEWNLKSGRV 391
NR A F Q+ GAGS++ G V +++PS VE HPVLEKLKA ++YNPK+F+WNLK+GRV
Sbjct: 359 NRGAGFNQNNGAGSENFGLGVVPVSASPSSVEVHPVLEKLKAINNYNPKDFDWNLKNGRV 418
Query: 392 FIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAE 451
FIIKSYSEDDIHRSIKYSIWCSTEHGNKRLD+A+R ++ KGP+YLLFSVNGSGHFCGVAE
Sbjct: 419 FIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDAAYRSLNGKGPLYLLFSVNGSGHFCGVAE 478
Query: 452 MKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEV 511
MKS VDY AGVWSQDKWKGKF+V+WIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEV
Sbjct: 479 MKSVVDYNAYAGVWSQDKWKGKFEVKWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEV 538
Query: 512 PLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ 559
PLEKAKQVLKII+++KHTTSIFDDFAHYEKRQEEEE +R+ER +RNKQ
Sbjct: 539 PLEKAKQVLKIIATFKHTTSIFDDFAHYEKRQEEEEAMRRER-NRNKQ 585
>gi|116812575 high glucose-regulated protein 8 [Homo sapiens]
Length = 579
Score = 747 bits (1929), Expect = 0.0
Identities = 378/584 (64%), Positives = 440/584 (75%), Gaps = 31/584 (5%)
Query: 1 MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYY 60
MSA+S+ QR KGQ NKVQNGS+HQKD ++D+DFEPYL+ Q+ +N+Y +MSD YL SYY
Sbjct: 1 MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYY 60
Query: 61 PPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIY--QH 118
PSIGF YSL EA WST GD +PYLT+YGQLSNG+ HF+ DA+FGQPG LG+ + QH
Sbjct: 61 SPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQH 120
Query: 119 RFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAP 178
FNFFP FSAWG + SQGQ TQSS Y S+Y Y PSSLGG ++DGQ F ++TL+KAP
Sbjct: 121 GFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAP 180
Query: 179 GMNSLEQGMVGLKIG--DVSSSAVKTVGSVVSSVALTG-VLSGNGGTNVNMPVSKPTSWA 235
GMN+++QGM LK+G +V+S+ K VGS V S ++T +++ N + KP SWA
Sbjct: 181 GMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWA 240
Query: 236 AIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP----VPQQAPS 291
IASKPAK QPK+KTK+G + G LPPPPIKHNMDIGTWDNKGPV KAP V
Sbjct: 241 DIASKPAKQQPKLKTKNG-IAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQP 299
Query: 292 PQAAPQPQ----------------QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRN 335
Q +PQP Q QPLP PP AQ Q P TRWVAPRNR
Sbjct: 300 TQGSPQPVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQP-TRWVAPRNRG 358
Query: 336 AAFGQSGGAGSDSNSPGNVQPNSAPSV-ESHPVLEKLKAAHSYNPKEFEWNLKSGRVFII 394
+ FG +G D N G Q S + E HPVLEKL++ ++YNPK+F+WNLK GRVFII
Sbjct: 359 SGFGHNG---VDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFII 415
Query: 395 KSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKS 454
KSYSEDDIHRSIKY+IWCSTEHGNKRLD+A+R M+ KGPVYLLFSVNGSGHFCGVAEMKS
Sbjct: 416 KSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKS 475
Query: 455 PVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLE 514
VDY T AGVWSQDKWKG+FDV+WIFVKDVPN+QLRHIRLENN+NKPVTNSRDTQEVPLE
Sbjct: 476 AVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLE 535
Query: 515 KAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNK 558
KAKQVLKII+SYKHTTSIFDDF+HYEKRQEEEE V+KERQ R K
Sbjct: 536 KAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK 579
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 73.6 bits (179), Expect = 5e-13
Identities = 55/189 (29%), Positives = 88/189 (46%), Gaps = 19/189 (10%)
Query: 338 FGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEK-LKAAHSYNPKEFEWNLKSGRVFIIKS 396
F +SG + S+S A S + H L ++A + ++ L+ R F+IKS
Sbjct: 312 FDRSGSSASESY---------AGSEKKHEKLSSSVRAVRKDQTSKLKYVLQDARFFLIKS 362
Query: 397 YSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPV 456
+ +++ + +W + K+L+ AFR S V L+FSV SG F G A + S
Sbjct: 363 NNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS---VILIFSVRESGKFQGFARLSSES 419
Query: 457 DYGTSAGVW------SQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQE 510
+G S W S G F + WI +++P + H+ N++KPV RD QE
Sbjct: 420 HHGGSPIHWVLPAGMSAKMLGGVFKIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQE 479
Query: 511 VPLEKAKQV 519
+ LE Q+
Sbjct: 480 IELECGTQL 488
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 71.2 bits (173), Expect = 2e-12
Identities = 48/133 (36%), Positives = 69/133 (51%), Gaps = 4/133 (3%)
Query: 390 RVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGV 449
R FI+KS + ++ S + IW +T ++L+ AF S VYL+FSV GSGHF G
Sbjct: 1289 RYFIMKSSNLRNLEISQQKGIWSTTPSNERKLNRAFWESSI---VYLVFSVQGSGHFQGF 1345
Query: 450 AEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQ 509
+ M S + S W G F V+WI + +P H+ NDNK V SRD Q
Sbjct: 1346 SRMSSEIGREKSQD-WGSAGLGGVFKVEWIRKESLPFQFAHHLLNPWNDNKKVQISRDGQ 1404
Query: 510 EVPLEKAKQVLKI 522
E+ +Q+L++
Sbjct: 1405 ELEPLVGEQLLQL 1417
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 70.5 bits (171), Expect = 4e-12
Identities = 48/155 (30%), Positives = 76/155 (49%), Gaps = 11/155 (7%)
Query: 373 AAHSY--NPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSS 430
A+ SY + ++ L+ R F+IKS + +++ + +W + K+L+ AFR S
Sbjct: 319 ASESYADQTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRSARS 378
Query: 431 KGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVW------SQDKWKGKFDVQWIFVKDV 484
V L+FSV SG F G A + S +G S W S G F + WI +++
Sbjct: 379 ---VILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVFKIDWICRREL 435
Query: 485 PNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQV 519
P + H+ N++KPV RD QE+ LE Q+
Sbjct: 436 PFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQL 470
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/209 (27%), Positives = 75/209 (35%), Gaps = 38/209 (18%)
Query: 124 PENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSL 183
P+ P T+ Q S + +P SS +V GQP P +
Sbjct: 732 PQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQP----------PAQTGV 781
Query: 184 EQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGN-------GGTNVNMPVSKPTSWAA 236
QG V G + + +G S + V T MP + T+
Sbjct: 782 SQGQVP---GAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPG 838
Query: 237 IASKPAKPQPKMKTK-SGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAA 295
+ PQP T+ S PV G P P G VP A Q P+ QAA
Sbjct: 839 MTP----PQPAAPTQPSTPVSSSGQTPTP-----------TPGSVPSATQTQSTPTVQAA 883
Query: 296 PQPQQVAQP-LPAQPPALAQPQYQSPQQP 323
Q Q QP P QPP++A PQ S QQP
Sbjct: 884 AQAQVTPQPQTPVQPPSVATPQ-SSQQQP 911
Score = 35.0 bits (79), Expect = 0.18
Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 40/151 (26%)
Query: 246 PKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSP------------- 292
P+ SGPVM +PP G W +AP+PQQ P P
Sbjct: 1965 PRPNQVSGPVMPS-MPP---------GQWQ------QAPLPQQQPMPGLPRPVISMQAQA 2008
Query: 293 -QAAPQPQQVAQPLPAQPPALAQ-----PQYQSPQQPPQTRWVAPRNRN--AAFGQSGGA 344
A P+ V P P AL SPQQ Q + N AAF + A
Sbjct: 2009 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2068
Query: 345 GSDSNSPGNVQPNSAPSVESHPVLEKLKAAH 375
+N PG +QP P ++S P ++ H
Sbjct: 2069 KYVANQPG-MQPQ--PGLQSQPGMQPQPGMH 2096
Score = 30.4 bits (67), Expect = 4.5
Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 9/126 (7%)
Query: 284 PVPQQAPSPQAAPQPQQVAQP-LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSG 342
P Q AP P+P QV+ P +P+ PP Q Q PQQ P PR + Q+
Sbjct: 1953 PGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ-QAPLPQQQPMPG--LPRPVISMQAQAA 2009
Query: 343 GAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDI 402
AG P P S +L LK+ S ++ N+ ++ ++ +
Sbjct: 2010 VAG--PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIK--- 2064
Query: 403 HRSIKY 408
R+ KY
Sbjct: 2065 QRTAKY 2070
Score = 30.0 bits (66), Expect = 5.8
Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 4/35 (11%)
Query: 285 VPQQA-PSPQAAP---QPQQVAQPLPAQPPALAQP 315
VPQQ+ PSP +AP QQ + P QPPA QP
Sbjct: 1839 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1873
Score = 29.3 bits (64), Expect = 10.0
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 8/66 (12%)
Query: 297 QPQQVAQP-LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQ 355
QPQ QP +P Q PA PQ Q R + P N +GG +D P +
Sbjct: 457 QPQTQLQPQVPGQQPA-------QPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLIS 509
Query: 356 PNSAPS 361
++ P+
Sbjct: 510 ESALPT 515
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 50.1 bits (118), Expect = 5e-06
Identities = 58/209 (27%), Positives = 75/209 (35%), Gaps = 38/209 (18%)
Query: 124 PENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSL 183
P+ P T+ Q S + +P SS +V GQP P +
Sbjct: 770 PQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQP----------PAQTGV 819
Query: 184 EQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGN-------GGTNVNMPVSKPTSWAA 236
QG V G + + +G S + V T MP + T+
Sbjct: 820 SQGQVP---GAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPG 876
Query: 237 IASKPAKPQPKMKTK-SGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAA 295
+ PQP T+ S PV G P P G VP A Q P+ QAA
Sbjct: 877 MTP----PQPAAPTQPSTPVSSSGQTPTP-----------TPGSVPSATQTQSTPTVQAA 921
Query: 296 PQPQQVAQP-LPAQPPALAQPQYQSPQQP 323
Q Q QP P QPP++A PQ S QQP
Sbjct: 922 AQAQVTPQPQTPVQPPSVATPQ-SSQQQP 949
Score = 35.0 bits (79), Expect = 0.18
Identities = 43/151 (28%), Positives = 56/151 (37%), Gaps = 40/151 (26%)
Query: 246 PKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSP------------- 292
P+ SGPVM +PP G W +AP+PQQ P P
Sbjct: 2003 PRPNQVSGPVMPS-MPP---------GQWQ------QAPLPQQQPMPGLPRPVISMQAQA 2046
Query: 293 -QAAPQPQQVAQPLPAQPPALAQ-----PQYQSPQQPPQTRWVAPRNRN--AAFGQSGGA 344
A P+ V P P AL SPQQ Q + N AAF + A
Sbjct: 2047 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2106
Query: 345 GSDSNSPGNVQPNSAPSVESHPVLEKLKAAH 375
+N PG +QP P ++S P ++ H
Sbjct: 2107 KYVANQPG-MQPQ--PGLQSQPGMQPQPGMH 2134
Score = 30.4 bits (67), Expect = 4.5
Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 9/126 (7%)
Query: 284 PVPQQAPSPQAAPQPQQVAQP-LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSG 342
P Q AP P+P QV+ P +P+ PP Q Q PQQ P PR + Q+
Sbjct: 1991 PGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ-QAPLPQQQPMPG--LPRPVISMQAQAA 2047
Query: 343 GAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDI 402
AG P P S +L LK+ S ++ N+ ++ ++ +
Sbjct: 2048 VAG--PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIK--- 2102
Query: 403 HRSIKY 408
R+ KY
Sbjct: 2103 QRTAKY 2108
Score = 30.0 bits (66), Expect = 5.8
Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 4/35 (11%)
Query: 285 VPQQA-PSPQAAP---QPQQVAQPLPAQPPALAQP 315
VPQQ+ PSP +AP QQ + P QPPA QP
Sbjct: 1877 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1911
Score = 29.3 bits (64), Expect = 10.0
Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 8/66 (12%)
Query: 297 QPQQVAQP-LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQ 355
QPQ QP +P Q PA PQ Q R + P N +GG +D P +
Sbjct: 495 QPQTQLQPQVPGQQPA-------QPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLIS 547
Query: 356 PNSAPS 361
++ P+
Sbjct: 548 ESALPT 553
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 48.9 bits (115), Expect = 1e-05
Identities = 40/119 (33%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 245 QPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQP 304
QP + GP+ G PPPP+ GP P P PQQ P P P P + P
Sbjct: 282 QPFGQPPLGPLPPG--PPPPVP---------GYGPPPGPPPPQQGPPPPPGPFPPR--PP 328
Query: 305 LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAF---GQSGGAGSDSNSPGNVQPNSAP 360
P PP P P PP AP A F SG SDS P P P
Sbjct: 329 GPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRP 387
Score = 31.6 bits (70), Expect = 2.0
Identities = 25/72 (34%), Positives = 27/72 (37%), Gaps = 15/72 (20%)
Query: 253 GPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPAL 312
GP GG PPPP G P P P P P P P Q LP P L
Sbjct: 219 GPAGPGG-PPPPFP----------AGQTPPRP-PLGPPGPPGPPGPPPPGQVLP---PPL 263
Query: 313 AQPQYQSPQQPP 324
A P + + PP
Sbjct: 264 AGPPNRGDRPPP 275
Score = 31.6 bits (70), Expect = 2.0
Identities = 30/104 (28%), Positives = 36/104 (34%), Gaps = 12/104 (11%)
Query: 227 PVSKPTSWAAIASKPAKP--QPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP 284
P P + A + P P P GP G + PPP+ N+G P P
Sbjct: 223 PGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGP------PNRGDRPPPP 276
Query: 285 V---PQQAPSPQAAPQPQQVAQPLPAQ-PPALAQPQYQSPQQPP 324
V Q P P P P+P PP P Q P PP
Sbjct: 277 VLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP 320
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/109 (31%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 231 PTSW---AAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDN---KGPVP--- 281
P SW + I P+ PQP+ + P+ P + + W++ + +P
Sbjct: 343 PRSWQPVSRIPMPPSSPQPRGAPRQRPI------PLSMIFKLQNAFWEHGASRAMLPGSP 396
Query: 282 ---KAPVPQQAPSPQAAPQPQQVAQP-LPAQPPALAQPQYQSPQQPPQT 326
+AP P+ P PQ PQPQ QP LP QP Q +PQ P QT
Sbjct: 397 LFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQT 445
Score = 32.7 bits (73), Expect = 0.90
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 278 GPVPKAPVPQQAP---SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQT 326
GP P P P+ +P +A P A P P PPA P SP + PQ+
Sbjct: 556 GPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA---PSQSSPPEQPQS 604
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 48.5 bits (114), Expect = 2e-05
Identities = 34/109 (31%), Positives = 48/109 (44%), Gaps = 19/109 (17%)
Query: 231 PTSW---AAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDN---KGPVP--- 281
P SW + I P+ PQP+ + P+ P + + W++ + +P
Sbjct: 343 PRSWQPVSRIPMPPSSPQPRGAPRQRPI------PLSMIFKLQNAFWEHGASRAMLPGSP 396
Query: 282 ---KAPVPQQAPSPQAAPQPQQVAQP-LPAQPPALAQPQYQSPQQPPQT 326
+AP P+ P PQ PQPQ QP LP QP Q +PQ P QT
Sbjct: 397 LFTRAPPPKLQPQPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQT 445
Score = 32.7 bits (73), Expect = 0.90
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 6/52 (11%)
Query: 278 GPVPKAPVPQQAP---SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQT 326
GP P P P+ +P +A P A P P PPA P SP + PQ+
Sbjct: 556 GPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPA---PSQSSPPEQPQS 604
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/162 (27%), Positives = 58/162 (35%), Gaps = 14/162 (8%)
Query: 217 SGNGGTNVNMPVSKPTSWAAI--------ASKPAKPQPKMKTKSGPVMGGGLPPPPIKH- 267
S GG P PT+ AA A+ P K P + P + GGL PP K
Sbjct: 1227 SPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA 1286
Query: 268 -NMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQT 326
N + T + P P+ AP+P AA P P P P +P P T
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346
Query: 327 RWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVL 368
P GG + S+ G P + PS + P +
Sbjct: 1347 ----PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Score = 42.0 bits (97), Expect = 0.001
Identities = 41/157 (26%), Positives = 50/157 (31%), Gaps = 15/157 (9%)
Query: 217 SGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDN 276
S GG P PT+ AA P K P PP P + T
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP---KGGLATPSP 1237
Query: 277 KG-PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPA----LAQPQYQSPQQPPQTRWVAP 331
KG P A P A P P+ P A PP+ LA P ++ P +P
Sbjct: 1238 KGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP 1297
Query: 332 RNRNAAFGQSGG-------AGSDSNSPGNVQPNSAPS 361
+ A G S SPG P AP+
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/132 (25%), Positives = 42/132 (31%), Gaps = 1/132 (0%)
Query: 231 PTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
P A S P P T P G P P T + P P P+ AP
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 291 SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNS 350
+P AA P P P P +P P + P + A+ + S S
Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 351 PGNVQ-PNSAPS 361
P P AP+
Sbjct: 1047 PAATPLPKGAPT 1058
Score = 37.0 bits (84), Expect = 0.048
Identities = 36/147 (24%), Positives = 48/147 (32%), Gaps = 11/147 (7%)
Query: 221 GTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPV 280
G + P+ +A+ P K P + P GGL PP K G
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPK-----GAPTTPAAT 1178
Query: 281 PKAPVPQQA-PSPQAAPQPQQVAQPLP----AQPPALAQPQYQSPQQP-PQTRWVAPRNR 334
P +P A PSP+ AP P P A P P + P P+ P +
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Query: 335 NAAFGQSGGAGSDSNSPGNVQPNSAPS 361
A + S P P AP+
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPT 1265
Score = 36.6 bits (83), Expect = 0.062
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 10/89 (11%)
Query: 241 PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKA---PVPQQAPSPQAAPQ 297
PA P PK + + P PP + + G P PK P +PSP+ AP
Sbjct: 1562 PAIPTPK-EAPATPSSKEASSPPAVTPSTYKGA-----PSPKELLIPPAVTSPSPKEAPT 1615
Query: 298 PQQVAQPLPAQPPALAQPQYQSPQQPPQT 326
P V P P + PA P+ +P PP T
Sbjct: 1616 PPAVTPPSPEKGPATPAPK-GTPTSPPVT 1643
Score = 35.8 bits (81), Expect = 0.11
Identities = 34/111 (30%), Positives = 42/111 (37%), Gaps = 11/111 (9%)
Query: 221 GTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSG---PVMGGGLPPPPIKHNMDIGTWDNK 277
G + P PTS A I P K T+ G P G PP ++ K
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL------KK 1445
Query: 278 GPVPKAPVPQQA-PSPQAAPQPQQVAQPLPAQPPALAQ-PQYQSPQQPPQT 326
P AP A PS + P V P P +PPA Q SP++ P T
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Score = 33.1 bits (74), Expect = 0.69
Identities = 34/135 (25%), Positives = 49/135 (36%), Gaps = 18/135 (13%)
Query: 235 AAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKA----PVPQQAP 290
A +A AK T + P + G + P H + GT VP A PV AP
Sbjct: 656 AGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPV---AP 712
Query: 291 SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFG----------- 339
SPQ P P P ++ P PP T+ V + +A
Sbjct: 713 SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPT 772
Query: 340 QSGGAGSDSNSPGNV 354
+ GA + ++S G +
Sbjct: 773 EDSGASATASSKGTL 787
Score = 32.3 bits (72), Expect = 1.2
Identities = 34/120 (28%), Positives = 39/120 (32%), Gaps = 11/120 (9%)
Query: 217 SGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDN 276
S GG P PT+ AA P K P PP P + T
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP---KGGLATPSP 1191
Query: 277 KG-PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPA----LAQPQYQSPQQPPQTRWVAP 331
KG P A P A P P+ A PP+ LA P SP+ P T P
Sbjct: 1192 KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP---SPKGAPTTPAATP 1248
Score = 31.2 bits (69), Expect = 2.6
Identities = 45/184 (24%), Positives = 61/184 (33%), Gaps = 26/184 (14%)
Query: 192 IGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTK 251
IG++SS V V +S LS G + PT S P P T
Sbjct: 821 IGNLSSP----VSPVEASFLPENSLSFQGSKDSPATTHSPTP----PSPKGAPTPSAVTP 872
Query: 252 SGPVMGGGLPPPPIKHNMDIGT-WDNKGPVPKAPVPQQAPS----------PQAAPQPQQ 300
P G LPP + + +GP P P+QAP+ +A P P+
Sbjct: 873 LSP-KGVTLPPKETPTPSVVNLPFPKEGPA--TPAPKQAPALSMTSSSPKKARATPAPKG 929
Query: 301 V-AQPLP---AQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQP 356
+ A P P PPA P + P +W GG + S P
Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPP 989
Query: 357 NSAP 360
+ P
Sbjct: 990 AATP 993
Score = 30.4 bits (67), Expect = 4.5
Identities = 51/232 (21%), Positives = 67/232 (28%), Gaps = 19/232 (8%)
Query: 124 PENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSL 183
P PA + G + A PPS GG G + + P S
Sbjct: 940 PTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP---SP 996
Query: 184 EQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAK 243
+ G + T S S A T G P S S AA
Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 244 PQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQ 303
P T P GG P +K P P A P A P P+
Sbjct: 1057 PTTPAATLPSPK--GGPATPSLKG----------APTPPAATPPSPKGGPATPSPKGAPM 1104
Query: 304 PLPAQPPA----LAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP 351
P A PP+ LA P ++ P +P+ A G + + +P
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 47.8 bits (112), Expect = 3e-05
Identities = 50/171 (29%), Positives = 65/171 (38%), Gaps = 28/171 (16%)
Query: 206 VVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPI 265
++ SVAL + S N+N VS+ S + IA P P P+ K G PPPP
Sbjct: 4 ILLSVALLALSSAQ---NLNEDVSQEESPSLIAGNPQGPSPQGGNKPQ-----GPPPPPG 55
Query: 266 KHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQ---PQQVAQPLPAQPPALAQ---PQYQS 319
K +GP P+ Q P P PQ PQ P PP Q PQ
Sbjct: 56 K---------PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGK 106
Query: 320 PQQPP-----QTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESH 365
PQ PP + + P + GG+ S S +P P E +
Sbjct: 107 PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 157
Score = 40.4 bits (93), Expect = 0.004
Identities = 32/109 (29%), Positives = 42/109 (38%), Gaps = 4/109 (3%)
Query: 218 GNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTK-SGPVMGGGLPPPPIKHNMDIGTWDN 276
G+ + P KP KP P P+ K GP G PP + + +
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS 143
Query: 277 KGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQ 325
P+ P Q+ +PQ P P A P QP A Q Q P +PPQ
Sbjct: 144 PPGKPQGPPQQEGNNPQGPPPP---AGGNPQQPQAPPAGQPQGPPRPPQ 189
Score = 33.1 bits (74), Expect = 0.69
Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 14/84 (16%)
Query: 239 SKPAKPQPKMKTKSGPVMGG----------GLP--PPPIKHNMDIGTWDNKGPVPKAPVP 286
+KP P P K + P GG G P PP + N G G P+ P
Sbjct: 116 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQA 175
Query: 287 QQAPSPQAAPQPQQVAQPLPAQPP 310
A PQ P+P Q + P++PP
Sbjct: 176 PPAGQPQGPPRPPQGGR--PSRPP 197
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/184 (26%), Positives = 70/184 (38%), Gaps = 26/184 (14%)
Query: 214 GVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGG-------------- 259
G S GG N PT+ +++S A P K + PV GG
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT 298
Query: 260 --LPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQY 317
LPPPP ++ + G + P+P PSP A Q P P + P LA +
Sbjct: 299 PNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 318 QSPQQPPQTRWVAPRNR--NAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAH 375
P P + AP R ++ S A S S+S + + P+ ++ P H
Sbjct: 358 SLP--PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-----SYPH 410
Query: 376 SYNP 379
S+ P
Sbjct: 411 SFPP 414
Score = 40.4 bits (93), Expect = 0.004
Identities = 76/332 (22%), Positives = 107/332 (32%), Gaps = 41/332 (12%)
Query: 47 SYPSMSDPYLS---SYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDA 103
SYP P S S PP P ++A WS PP P YG+L + H
Sbjct: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP----YGRLLANSN--AHPG 460
Query: 104 VFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVV 163
F G + + + Q QQ Q +G+S PP + +
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-L 519
Query: 164 DGQPGFHSDTLSKAPGMNSLEQGMVG-----LKIGDVSSSAVKTVGSVVSSVALTGVLSG 218
+G H+ + +P + SL G VS S G VSS + + +
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 219 NGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKG 278
G + P P+ A P P P + T S + + I T
Sbjct: 580 QGSYPCSHP--SPSQGPQGAPYPFPPVPTVTTSSATL------------STVIAT----- 620
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAF 338
V +P + SP P P P P P Y+ P PP R P
Sbjct: 621 -VASSPAGYKTASP-PGPPPYGKRAPSPGAYKTATPPGYK-PGSPPSFRTGTPPGYRGTS 677
Query: 339 GQSGGA----GSDSNSPGNVQPNSAPSVESHP 366
+G GS + PG + P + S P
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709
Score = 29.3 bits (64), Expect = 10.0
Identities = 30/137 (21%), Positives = 46/137 (33%), Gaps = 30/137 (21%)
Query: 258 GGLPPPPIK--------HNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQ----------PQ 299
GGLPP P K H++ + P + P + S AA P
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF 399
Query: 300 QVAQPLPAQPPALAQP----------QYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSN 349
+Q LP+ P + P +Y P P Q W +G+ + +
Sbjct: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL--LANSNA 457
Query: 350 SPGNVQPNSAPSVESHP 366
PG P++ +HP
Sbjct: 458 HPGPFPPSTGAQSTAHP 474
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 47.4 bits (111), Expect = 4e-05
Identities = 48/184 (26%), Positives = 70/184 (38%), Gaps = 26/184 (14%)
Query: 214 GVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGG-------------- 259
G S GG N PT+ +++S A P K + PV GG
Sbjct: 239 GAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVT 298
Query: 260 --LPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQY 317
LPPPP ++ + G + P+P PSP A Q P P + P LA +
Sbjct: 299 PNLPPPPALRPLNNASASPPG-LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPH 357
Query: 318 QSPQQPPQTRWVAPRNR--NAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAH 375
P P + AP R ++ S A S S+S + + P+ ++ P H
Sbjct: 358 SLP--PASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALP-----SYPH 410
Query: 376 SYNP 379
S+ P
Sbjct: 411 SFPP 414
Score = 40.4 bits (93), Expect = 0.004
Identities = 76/332 (22%), Positives = 107/332 (32%), Gaps = 41/332 (12%)
Query: 47 SYPSMSDPYLS---SYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDA 103
SYP P S S PP P ++A WS PP P YG+L + H
Sbjct: 407 SYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPP----YGRLLANSN--AHPG 460
Query: 104 VFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVV 163
F G + + + Q QQ Q +G+S PP + +
Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-L 519
Query: 164 DGQPGFHSDTLSKAPGMNSLEQGMVG-----LKIGDVSSSAVKTVGSVVSSVALTGVLSG 218
+G H+ + +P + SL G VS S G VSS + + +
Sbjct: 520 EGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTS 579
Query: 219 NGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKG 278
G + P P+ A P P P + T S + + I T
Sbjct: 580 QGSYPCSHP--SPSQGPQGAPYPFPPVPTVTTSSATL------------STVIAT----- 620
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAF 338
V +P + SP P P P P P Y+ P PP R P
Sbjct: 621 -VASSPAGYKTASP-PGPPPYGKRAPSPGAYKTATPPGYK-PGSPPSFRTGTPPGYRGTS 677
Query: 339 GQSGGA----GSDSNSPGNVQPNSAPSVESHP 366
+G GS + PG + P + S P
Sbjct: 678 PPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLP 709
Score = 29.3 bits (64), Expect = 10.0
Identities = 30/137 (21%), Positives = 46/137 (33%), Gaps = 30/137 (21%)
Query: 258 GGLPPPPIK--------HNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQ----------PQ 299
GGLPP P K H++ + P + P + S AA P
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF 399
Query: 300 QVAQPLPAQPPALAQP----------QYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSN 349
+Q LP+ P + P +Y P P Q W +G+ + +
Sbjct: 400 PASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL--LANSNA 457
Query: 350 SPGNVQPNSAPSVESHP 366
PG P++ +HP
Sbjct: 458 HPGPFPPSTGAQSTAHP 474
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 47.4 bits (111), Expect = 4e-05
Identities = 81/344 (23%), Positives = 120/344 (34%), Gaps = 58/344 (16%)
Query: 49 PSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQP 108
P P L S PP P ++ P + P PY + Q S H + QP
Sbjct: 504 PQSQPPQLQSSQPPYSQQP---SQPPHQQS---PAPYPS---QQSTTQQHPQSQPPYSQP 554
Query: 109 GGLGNNIYQHRFNFFPENPAFSAWGTSGS----QGQQTQSSAYGSSYTYPPSSLGGTVVD 164
+ YQ + P+ PA S + Q QQ+Q +AY PP L
Sbjct: 555 QA--QSPYQQQQ---PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL------ 603
Query: 165 GQPGFHSDTLSKAPGMNSLEQGMVGLKI-------------GDVSSSAVKTVGSVVSSVA 211
Q F S S AP M S + G + + G + + T G++ V+
Sbjct: 604 SQDSFGSQA-SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
Query: 212 LTGVLSGNG--GTNVNMPVSKPTSWAAIASKPAKPQP------KMKTKSGP-----VMGG 258
+G+ S G P S TS + P P +++SGP V G
Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722
Query: 259 GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQ 318
+PP P D + + ++ + Q Q PQ Q + P QP + P+
Sbjct: 723 QMPPRPPSGQSDSIMHPS---MNQSSIAQDRGYMQRNPQMPQYSSP---QPGSALSPRQP 776
Query: 319 SPQQPPQTRWVAPRNRNAAFGQSGGA-GSDSNSPGNVQPNSAPS 361
S Q +N ++G GG G P N+ P+
Sbjct: 777 SGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPN 820
Score = 45.4 bits (106), Expect = 1e-04
Identities = 95/455 (20%), Positives = 147/455 (32%), Gaps = 111/455 (24%)
Query: 15 DNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAP 74
D K NG+ + +++N EP G S+ + ++ PP+ GF +P
Sbjct: 99 DLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP 158
Query: 75 WSTAGDPPIPYLTTYGQLSN------------------GDHHFMHDAVFGQPGGLGNNIY 116
+ A + +G + G HD G P N+ Y
Sbjct: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHD--HGFPNHQYNSYY 216
Query: 117 QHRFNFFPENPAFS------------AWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVD 164
+R + P PA++ A +GS+ + S++ SS + G +
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276
Query: 165 GQP---GFHSDTLSKAPGMNSL------EQGMVGLKIGDVSSS-------------AVKT 202
G P G + + P +N L +G G GD S A +
Sbjct: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQC 336
Query: 203 VGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQP--------KMKTK--- 251
G+ ++ A G + + P+S +S PQP KM+ +
Sbjct: 337 WGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG 396
Query: 252 ------------SGPVMGGGLPPPP-----------------------IKHNMDIGTWDN 276
SGP G G P P + + I +
Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQ 456
Query: 277 KGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPAL---AQPQY-QSPQ-QPPQTRWVAP 331
+GP Q Q +P PQQ P QPP+ AQP Y Q PQ QPPQ + P
Sbjct: 457 QGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516
Query: 332 RNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHP 366
+ Q SP P+ + + HP
Sbjct: 517 -----PYSQQPSQPPHQQSPA-PYPSQQSTTQQHP 545
Score = 39.7 bits (91), Expect = 0.007
Identities = 39/148 (26%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 227 PVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPP----PIKHNMDIGTWDNKGPVPK 282
P P + + +P P++++ P PP P + T + P +
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST-TQQHPQSQ 548
Query: 283 APVPQ-QAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQP--PQTRWVAPRNRNA-AF 338
P Q QA SP QPQQ A +Q A QPQ Q QQ Q R+ P+ + +F
Sbjct: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
Query: 339 GQSGGAGSDSNSPGNVQPNSAPSVESHP 366
G + S Q + S++S P
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRP 636
Score = 32.3 bits (72), Expect = 1.2
Identities = 33/98 (33%), Positives = 38/98 (38%), Gaps = 14/98 (14%)
Query: 286 PQQAPSPQAAPQP---QQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSG 342
PQQ P A PQP QQ AQP P Q QY + P T A R A Q+
Sbjct: 1400 PQQQQLPPAQPQPASQQQAAQPSPQQD---VYNQYGNAY--PATATAATERRPAGGPQNQ 1454
Query: 343 -----GAGSDSNSPG-NVQPNSAPSVESHPVLEKLKAA 374
G S PG N Q N P + P+ + A
Sbjct: 1455 FPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQASAEVA 1492
Score = 31.6 bits (70), Expect = 2.0
Identities = 74/343 (21%), Positives = 111/343 (32%), Gaps = 71/343 (20%)
Query: 44 QSNSYPSMSDP--YLSSYYPP-----------SIGFPYSLNEAPWSTAGDPPIPYLTTYG 90
Q N PS D Y S YPP S G +S P +G P TT
Sbjct: 1306 QPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGTP---SGSPFPSQQTTMY 1362
Query: 91 QLSNGDHHFMHDAVFGQPG--------------GLGNNIYQHRFNFFPENPAFSAWGTSG 136
Q ++ D +G P G G Q P+ PA
Sbjct: 1363 QQQQQNYKRPMDGTYGPPAKRHEGEMYSVPYSTGQGQPQQQQLPPAQPQ-PASQQQAAQP 1421
Query: 137 SQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPG------FHSDTLSKAPGMNSLEQGMVGL 190
S QQ + YG++Y ++ G P F D +S PG N+ + +
Sbjct: 1422 SP-QQDVYNQYGNAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQM 1480
Query: 191 KIGDVSSSAV---------------------KTVGSVVSSVALTGVLSGNGGTNVNMPVS 229
G + +SA ++ GS A GV + + + +
Sbjct: 1481 MGGPIQASAEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRAN 1540
Query: 230 KPTSWAAIASK-----PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP 284
SW + ++ P+ P P M + P PPP +++++ P P
Sbjct: 1541 HEGSWPSHGTRQPPYGPSAPVPPM---TRPPPSNYQPPPSMQNHIP----QVSSPAPLPR 1593
Query: 285 VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTR 327
+ SP +P + A PP A +P QPP R
Sbjct: 1594 PMENRTSPSKSPFLHSGMKMQKAGPPVPASHIAPAPVQPPMIR 1636
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 47.4 bits (111), Expect = 4e-05
Identities = 81/344 (23%), Positives = 120/344 (34%), Gaps = 58/344 (16%)
Query: 49 PSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQP 108
P P L S PP P ++ P + P PY + Q S H + QP
Sbjct: 504 PQSQPPQLQSSQPPYSQQP---SQPPHQQS---PAPYPS---QQSTTQQHPQSQPPYSQP 554
Query: 109 GGLGNNIYQHRFNFFPENPAFSAWGTSGS----QGQQTQSSAYGSSYTYPPSSLGGTVVD 164
+ YQ + P+ PA S + Q QQ+Q +AY PP L
Sbjct: 555 QA--QSPYQQQQ---PQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL------ 603
Query: 165 GQPGFHSDTLSKAPGMNSLEQGMVGLKI-------------GDVSSSAVKTVGSVVSSVA 211
Q F S S AP M S + G + + G + + T G++ V+
Sbjct: 604 SQDSFGSQA-SSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVS 662
Query: 212 LTGVLSGNG--GTNVNMPVSKPTSWAAIASKPAKPQP------KMKTKSGP-----VMGG 258
+G+ S G P S TS + P P +++SGP V G
Sbjct: 663 TSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPGN 722
Query: 259 GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQ 318
+PP P D + + ++ + Q Q PQ Q + P QP + P+
Sbjct: 723 QMPPRPPSGQSDSIMHPS---MNQSSIAQDRGYMQRNPQMPQYSSP---QPGSALSPRQP 776
Query: 319 SPQQPPQTRWVAPRNRNAAFGQSGGA-GSDSNSPGNVQPNSAPS 361
S Q +N ++G GG G P N+ P+
Sbjct: 777 SGGQIHTGMGSYQQNSMGSYGPQGGQYGPQGGYPRQPNYNALPN 820
Score = 45.4 bits (106), Expect = 1e-04
Identities = 95/455 (20%), Positives = 147/455 (32%), Gaps = 111/455 (24%)
Query: 15 DNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAP 74
D K NG+ + +++N EP G S+ + ++ PP+ GF +P
Sbjct: 99 DLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP 158
Query: 75 WSTAGDPPIPYLTTYGQLSN------------------GDHHFMHDAVFGQPGGLGNNIY 116
+ A + +G + G HD G P N+ Y
Sbjct: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHD--HGFPNHQYNSYY 216
Query: 117 QHRFNFFPENPAFS------------AWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVD 164
+R + P PA++ A +GS+ + S++ SS + G +
Sbjct: 217 PNRSAYPPPAPAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGG 276
Query: 165 GQP---GFHSDTLSKAPGMNSL------EQGMVGLKIGDVSSS-------------AVKT 202
G P G + + P +N L +G G GD S A +
Sbjct: 277 GGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQC 336
Query: 203 VGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQP--------KMKTK--- 251
G+ ++ A G + + P+S +S PQP KM+ +
Sbjct: 337 WGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYG 396
Query: 252 ------------SGPVMGGGLPPPP-----------------------IKHNMDIGTWDN 276
SGP G G P P + + I +
Sbjct: 397 GTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQ 456
Query: 277 KGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPAL---AQPQY-QSPQ-QPPQTRWVAP 331
+GP Q Q +P PQQ P QPP+ AQP Y Q PQ QPPQ + P
Sbjct: 457 QGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQP 516
Query: 332 RNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHP 366
+ Q SP P+ + + HP
Sbjct: 517 -----PYSQQPSQPPHQQSPA-PYPSQQSTTQQHP 545
Score = 39.7 bits (91), Expect = 0.007
Identities = 39/148 (26%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 227 PVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPP----PIKHNMDIGTWDNKGPVPK 282
P P + + +P P++++ P PP P + T + P +
Sbjct: 490 PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQST-TQQHPQSQ 548
Query: 283 APVPQ-QAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQP--PQTRWVAPRNRNA-AF 338
P Q QA SP QPQQ A +Q A QPQ Q QQ Q R+ P+ + +F
Sbjct: 549 PPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELSQDSF 608
Query: 339 GQSGGAGSDSNSPGNVQPNSAPSVESHP 366
G + S Q + S++S P
Sbjct: 609 GSQASSAPSMTSSKGGQEDMNLSLQSRP 636
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 47.0 bits (110), Expect = 5e-05
Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 19/119 (15%)
Query: 262 PPPIKHNMDIGTWDNKGPV--------PKAPVPQQAP-SPQAAPQPQQVA--QPLPAQPP 310
PPP +G N+GP+ PK P+P P Q P PQQ QP P QPP
Sbjct: 34 PPP-----GMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPP 88
Query: 311 ALAQP-QYQSPQQPPQ--TRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHP 366
QP Q Q P PPQ ++ V + A G + S++P P S S P
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP 147
Score = 43.9 bits (102), Expect = 4e-04
Identities = 35/118 (29%), Positives = 43/118 (36%), Gaps = 10/118 (8%)
Query: 253 GPVMGGGLPP--PPIKHNMDIGTWDNKGPVPKAPVPQQAP--SPQAAPQPQQVAQPLPAQ 308
GP G PP PP H + P P+ P PQQ P P PQP Q QP P
Sbjct: 50 GPGQSGPKPPIPPPPPHQQQ------QQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPP 103
Query: 309 PPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHP 366
+ Q P P P + +A +G+ S P P+V S P
Sbjct: 104 QDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161
Score = 35.8 bits (81), Expect = 0.11
Identities = 36/134 (26%), Positives = 43/134 (32%), Gaps = 23/134 (17%)
Query: 227 PVSKPTSWAAIASKPAKPQPKMKTKSG----PVMGGGLPPPPIKHNMDIGTWDNKGPVP- 281
P PT A+ S P P SG P GG PPPP VP
Sbjct: 147 PGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPP-------------AAVPG 193
Query: 282 KAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAP---RNRNAAF 338
P P+Q P P + P P P L+ P +PP P R + +
Sbjct: 194 PGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTP--GGHPKPPHRGGGEPRGGRQHHPPY 251
Query: 339 GQSGGAGSDSNSPG 352
Q G PG
Sbjct: 252 HQQHHQGPPPGGPG 265
Score = 34.3 bits (77), Expect = 0.31
Identities = 36/141 (25%), Positives = 44/141 (31%), Gaps = 24/141 (17%)
Query: 243 KPQPKMKTKSGPVMGGGLPP-------PPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAA 295
+P P + S PV+ G P PP + T P AP P P P
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPAT----PPTSGAP-PGSGPGPTPT 152
Query: 296 PQPQQVAQPLPAQPPA-------LAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDS 348
P P + P A PP PQ P PP V G G
Sbjct: 153 PPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAA--VPGPGPGPKQGPGPGGPKGG 210
Query: 349 NSPGNVQPNSAPSVES---HP 366
PG +P P + + HP
Sbjct: 211 KMPGGPKPGGGPGLSTPGGHP 231
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/114 (31%), Positives = 43/114 (37%), Gaps = 22/114 (19%)
Query: 227 PVSKPTSWAAIASKPAKPQ--------PKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKG 278
P S P S +A A P P S P+ PPP +
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP-------------QA 726
Query: 279 PVPKAPVPQQAP-SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAP 331
P P A P Q P SP A+P A P P PP LA P Q P PP + ++P
Sbjct: 727 PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Score = 46.2 bits (108), Expect = 8e-05
Identities = 46/151 (30%), Positives = 57/151 (37%), Gaps = 28/151 (18%)
Query: 227 PVSKPTSWAAIASKPAKPQ--------PKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKG 278
P S P S +A A P P S P+ PPP +
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP------------ 758
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAF 338
P+ AP Q PSP A+ +A+P P PPALA P Q+ PP A A F
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP-----ASFPGQAPF 813
Query: 339 GQSGGAGSDSNSPGNVQPNSAPSVESHPVLE 369
S S SP P AP V + P+L+
Sbjct: 814 SPS---ASLPMSPLATPPPQAPPVLAAPLLQ 841
Score = 45.8 bits (107), Expect = 1e-04
Identities = 45/138 (32%), Positives = 67/138 (48%), Gaps = 12/138 (8%)
Query: 231 PTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
P + ++IA+ P + P + S P+ G LP PP+ + T + P A P QAP
Sbjct: 581 PETPSSIATPPPQAPPALA--SPPLQG--LPSPPLS---PLATPPPQAPPXLALPPLQAP 633
Query: 291 -SPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWV-APRNRNAAFGQSGGAGSDS 348
SP A+P +A P P P ALA Q+P PP + V AP + A+ S A S
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693
Query: 349 NSPGNVQPNSAPSVESHP 366
+P ++ +AP ++ P
Sbjct: 694 QAPPSL---AAPPLQVPP 708
Score = 45.1 bits (105), Expect = 2e-04
Identities = 36/127 (28%), Positives = 55/127 (43%), Gaps = 6/127 (4%)
Query: 211 ALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMG-GGLPPPPIKH-N 268
AL+ + S + ++ + P + + P+ P + P+ L PPP++ +
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550
Query: 269 MDIGTWDNKGPVPKAPVPQQA-PSPQAAPQPQ---QVAQPLPAQPPALAQPQYQSPQQPP 324
+ T + P AP P QA PSP P P+ +A P P PPALA P Q PP
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 325 QTRWVAP 331
+ P
Sbjct: 611 LSPLATP 617
Score = 43.1 bits (100), Expect = 7e-04
Identities = 33/94 (35%), Positives = 41/94 (43%), Gaps = 11/94 (11%)
Query: 241 PAKPQPKMKTKSGPVMGGGLPP--PPIKHNMDIGTWDNKGPVPKAPVPQQAP-SPQAAPQ 297
P P P S PV PP PP+ + T ++ P A P Q P SP A+P
Sbjct: 664 PFSPPP-----SPPVQAPFSPPASPPVSPS---ATPPSQAPPSLAAPPLQVPPSPPASPP 715
Query: 298 PQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAP 331
A P P PP LA P Q P PP + ++P
Sbjct: 716 MSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/97 (35%), Positives = 42/97 (43%), Gaps = 16/97 (16%)
Query: 238 ASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP-SPQAAP 296
AS P P K ++ P L PP++ P P A P QAP SP A+
Sbjct: 774 ASLPMSPLAKPPPQAPPA----LATPPLQAL----------PSPPASFPGQAPFSPSASL 819
Query: 297 QPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWV-APR 332
+A P P PP LA P Q P PP + + APR
Sbjct: 820 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/105 (27%), Positives = 42/105 (40%), Gaps = 19/105 (18%)
Query: 229 SKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQ 288
S P + + + A+P P + P+ P PP+ P+P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA----------------TPLPLA 344
Query: 289 APSPQAAPQPQQVAQPLPAQPPALAQPQYQSP--QQPPQTRWVAP 331
PSP A P Q + P PA PP+ A P +P Q PP + + P
Sbjct: 345 PPSPSAPPSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPP 388
Score = 38.5 bits (88), Expect = 0.016
Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Query: 241 PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP-SPQAAPQPQ 299
P P S P+ P P + + + P +P P QAP SP A+P
Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVS 686
Query: 300 QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAP 331
A P PP+LA P Q P PP + ++P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718
Score = 36.6 bits (83), Expect = 0.062
Identities = 33/105 (31%), Positives = 42/105 (40%), Gaps = 15/105 (14%)
Query: 224 VNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKA 283
+ +P S P S S AKP P+ LP PP G P +
Sbjct: 766 LQVPPSPPASLPM--SPLAKPPPQAPPALATPPLQALPSPPASF---------PGQAPFS 814
Query: 284 PVPQQAPSPQAAPQPQQ---VAQPLPAQPPAL-AQPQYQSPQQPP 324
P SP A P PQ +A PL PP+ A P Q+P++PP
Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 859
Score = 29.6 bits (65), Expect = 7.6
Identities = 31/122 (25%), Positives = 41/122 (33%), Gaps = 15/122 (12%)
Query: 275 DNKGPVPKAPVPQQAPSPQAA------PQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRW 328
D GP P P P A +AA P+P A+P P S +
Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP 222
Query: 329 VAPRNRNAAFGQSGGAG---SDSNSPGNVQPNSAPSVE------SHPVLEKLKAAHSYNP 379
A R +A G A S S +P + S PS +HP K K + P
Sbjct: 223 AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Query: 380 KE 381
+
Sbjct: 283 PQ 284
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 46.6 bits (109), Expect = 6e-05
Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 9/139 (6%)
Query: 227 PVSKPTSWAAIAS-KPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPV 285
P PT +A+A KPA P + S P PPP+K + P P P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAP-------PPPLKIHQVQHITQVAPPTPPPPP 767
Query: 286 PQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAG 345
P AP P AP V P P +A P P T V P + AF S
Sbjct: 768 PIPAPLPPQAPPKPLVTIPAPTSTKTVA-PVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 346 SDSNSPGNVQPNSAPSVES 364
S P V P + P +S
Sbjct: 827 SPPTPPVPVPPPTLPKQQS 845
Score = 40.4 bits (93), Expect = 0.004
Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 14/148 (9%)
Query: 198 SAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPA-KPQPKMKTKSGPVM 256
S + V SVV +A + P+ + A S PA K +PK + S PV
Sbjct: 853 SPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP 912
Query: 257 GGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQ 316
PPPP + ++ + PVP P P P P A+P P + P + + P
Sbjct: 913 SPDFPPPPPESSL-VFPPPPPSPVPAPPPP---PPPTASPTPDKSGSP-GKKTSKTSSPG 967
Query: 317 YQSPQQPPQTRWVAPRNRNAAFGQSGGA 344
+ P PQ RN++ S GA
Sbjct: 968 GKKPPPTPQ--------RNSSIKSSSGA 987
Score = 40.0 bits (92), Expect = 0.006
Identities = 38/139 (27%), Positives = 50/139 (35%), Gaps = 23/139 (16%)
Query: 242 AKPQPKMKTKSGPVM---GGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQP 298
AKP P + V+ PPPP M+ PVP PQ P+ +A P+
Sbjct: 848 AKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK---PVPANVAPQSPPAVKAKPKW 904
Query: 299 QQVAQPLPAQ-------------PPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAG 345
Q + P+P+ PP P P PP T P G G
Sbjct: 905 QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS----GSPGKKT 960
Query: 346 SDSNSPGNVQPNSAPSVES 364
S ++SPG +P P S
Sbjct: 961 SKTSSPGGKKPPPTPQRNS 979
Score = 33.5 bits (75), Expect = 0.53
Identities = 32/131 (24%), Positives = 42/131 (32%), Gaps = 22/131 (16%)
Query: 244 PQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQ 303
P P PV+ PP P PVP P +Q P + P
Sbjct: 786 PAPTSTKTVAPVVTQAAPPTPTP------------PVP--PAKKQPAFPASYIPPSPPTP 831
Query: 304 PLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSD--------SNSPGNVQ 355
P+P PP L + Q + PP P Q + P NV
Sbjct: 832 PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVA 891
Query: 356 PNSAPSVESHP 366
P S P+V++ P
Sbjct: 892 PQSPPAVKAKP 902
Score = 29.6 bits (65), Expect = 7.6
Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 24/106 (22%)
Query: 241 PAKPQPKMKTKSGPVMGGGLPPPPIKHNMDI---GTWDNKGPVPKAPVP----QQAPSPQ 293
P P P + ++S P G P +K++ + G + K P P Q+ PQ
Sbjct: 642 PPPPPPPLPSQSAP-SAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQ 700
Query: 294 AAPQPQQVAQPLPAQPP------ALAQ----------PQYQSPQQP 323
P V P P PP A+AQ PQ+ +P P
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPP 746
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 12/201 (5%)
Query: 174 LSKAPGMNSLEQGMVGLKIGDVSSSA---VKTVGSVVSSVALTGVLSGNGGTNVNMPVSK 230
L+K P + ++E GL+ G+ ++A + T S L ++G G + +P ++
Sbjct: 557 LAKGPELMAIE----GLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPAR 612
Query: 231 PTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
S +I ++ ++ + + P GG P PP + N+ GT + P + +P Q P
Sbjct: 613 SPSQESIGAR-SRGSGHSQEQPAPQPSGGDPSPPQERNLPEGT--ERPPKLCSSLPGQGP 669
Query: 291 SPQAAPQPQ-QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSN 349
P PQ + P P PP A + PP T PR + + S ++ +
Sbjct: 670 PPYVFMYPQGSPSSPAPGPPPG-APWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGD 728
Query: 350 SPGNVQPNSAPSVESHPVLEK 370
+ G + ++ S+ L +
Sbjct: 729 AEGEAEGPVGSTLGSYATLTR 749
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/148 (23%), Positives = 56/148 (37%), Gaps = 26/148 (17%)
Query: 193 GDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKS 252
GD A VGS + S A G P PT PA+ P+ ++ +
Sbjct: 727 GDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT--------PARGTPRSQSFA 778
Query: 253 GPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQ---AAPQPQQVAQP----- 304
G PPPP K + GP P+ P ++P P+ P+ + +++P
Sbjct: 779 LRARRKGPPPPPPKRLSSVS-----GPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 833
Query: 305 -----LPAQPPALAQPQYQSPQQPPQTR 327
PA P + + + P+ P +R
Sbjct: 834 PPGPPAPAGPASDTEEEEPGPEGTPPSR 861
Score = 33.9 bits (76), Expect = 0.40
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSP---QQPPQTRWVAPRNRN 335
P P AP+P +P+P +P + QP P+ PA P +P QPP P
Sbjct: 934 PGPAAPLP--SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGP---- 987
Query: 336 AAFGQSGGAGSDSNSPGNVQPNSAPS 361
G A S N G +P +AP+
Sbjct: 988 ---GLESSAASRWN--GETEPPAAPA 1008
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 45.4 bits (106), Expect = 1e-04
Identities = 46/201 (22%), Positives = 86/201 (42%), Gaps = 12/201 (5%)
Query: 174 LSKAPGMNSLEQGMVGLKIGDVSSSA---VKTVGSVVSSVALTGVLSGNGGTNVNMPVSK 230
L+K P + ++E GL+ G+ ++A + T S L ++G G + +P ++
Sbjct: 639 LAKGPELMAIE----GLENGEGPATAGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPAR 694
Query: 231 PTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
S +I ++ ++ + + P GG P PP + N+ GT + P + +P Q P
Sbjct: 695 SPSQESIGAR-SRGSGHSQEQPAPQPSGGDPSPPQERNLPEGT--ERPPKLCSSLPGQGP 751
Query: 291 SPQAAPQPQ-QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSN 349
P PQ + P P PP A + PP T PR + + S ++ +
Sbjct: 752 PPYVFMYPQGSPSSPAPGPPPG-APWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGD 810
Query: 350 SPGNVQPNSAPSVESHPVLEK 370
+ G + ++ S+ L +
Sbjct: 811 AEGEAEGPVGSTLGSYATLTR 831
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/148 (23%), Positives = 56/148 (37%), Gaps = 26/148 (17%)
Query: 193 GDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKS 252
GD A VGS + S A G P PT PA+ P+ ++ +
Sbjct: 809 GDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPT--------PARGTPRSQSFA 860
Query: 253 GPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQ---AAPQPQQVAQP----- 304
G PPPP K + GP P+ P ++P P+ P+ + +++P
Sbjct: 861 LRARRKGPPPPPPKRLSSVS-----GPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSE 915
Query: 305 -----LPAQPPALAQPQYQSPQQPPQTR 327
PA P + + + P+ P +R
Sbjct: 916 PPGPPAPAGPASDTEEEEPGPEGTPPSR 943
Score = 33.9 bits (76), Expect = 0.40
Identities = 27/86 (31%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSP---QQPPQTRWVAPRNRN 335
P P AP+P +P+P +P + QP P+ PA P +P QPP P
Sbjct: 1016 PGPAAPLP--SPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGP---- 1069
Query: 336 AAFGQSGGAGSDSNSPGNVQPNSAPS 361
G A S N G +P +AP+
Sbjct: 1070 ---GLESSAASRWN--GETEPPAAPA 1090
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 45.4 bits (106), Expect = 1e-04
Identities = 48/161 (29%), Positives = 64/161 (39%), Gaps = 16/161 (9%)
Query: 206 VVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTK-SGPVMGGGLP--P 262
++ SVAL + S N+N VS+ S + IA P P+ K GP G P P
Sbjct: 4 ILLSVALLALSSAQ---NLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP 60
Query: 263 PPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQ 322
PP N +GP P P Q P PQ +PQ P Q P + +SP+
Sbjct: 61 PPQGGNQP------QGP-PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRS 113
Query: 323 PP-QTRWVAPRNRNAAFGQSGGAGSDSNSP--GNVQPNSAP 360
PP + + P+ N G G P G +P P
Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 8/131 (6%)
Query: 244 PQPKMKTKSGPVMGGGLP---PPPIKHNMDIGTWDNKGPVPKAPVPQ-QAPSPQAAPQPQ 299
P P K + P GG P PPP K DNK ++P + Q P PQ QPQ
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQ 192
Query: 300 QVAQP--LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP--GNVQ 355
P P PP + Q P P + + P+ N + G P G Q
Sbjct: 193 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ 252
Query: 356 PNSAPSVESHP 366
P P P
Sbjct: 253 PQGPPPPPGKP 263
Score = 43.5 bits (101), Expect = 5e-04
Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 8/131 (6%)
Query: 244 PQPKMKTKSGPVMGGGLP---PPPIKHNMDIGTWDNKGPVPKAPVPQ-QAPSPQAAPQPQ 299
P P K + P GG P PPP K DNK ++P + Q P PQ QPQ
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQ 254
Query: 300 QVAQP--LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP--GNVQ 355
P P PP + Q P P + + P+ + + G P G Q
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314
Query: 356 PNSAPSVESHP 366
P P P
Sbjct: 315 PQGPPPPPGKP 325
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/117 (30%), Positives = 42/117 (35%), Gaps = 16/117 (13%)
Query: 239 SKPAKPQPKMKTKSGPVMGG----GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQA 294
S P KPQ P GG G PPPP K NK P P Q P PQ
Sbjct: 299 SPPGKPQ------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352
Query: 295 APQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP 351
+ + P P +P Q + +PQ PP P N Q+ AG P
Sbjct: 353 GSKSRSARSP-PGKPQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403
Score = 39.7 bits (91), Expect = 0.007
Identities = 32/92 (34%), Positives = 33/92 (35%), Gaps = 12/92 (13%)
Query: 239 SKPAKPQPKMKTKSGPVMGG----GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQA 294
S P KPQ P GG G PPPP K NK P P Q P PQ
Sbjct: 175 SPPGKPQ------GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228
Query: 295 APQPQQVAQP--LPAQPPALAQPQYQSPQQPP 324
+ Q P P PP Q Q P PP
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Score = 36.6 bits (83), Expect = 0.062
Identities = 34/126 (26%), Positives = 46/126 (36%), Gaps = 11/126 (8%)
Query: 244 PQPKMKTKSGPVMGGGLP---PPPIKHNMDIGTWDNKGPVPKAPVPQ-QAPSPQAAPQPQ 299
P P K + P GG P PPP K +K ++P + Q P PQ QPQ
Sbjct: 257 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ 316
Query: 300 QVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSA 359
PP +PQ PQ + + P + GG+ S S +P
Sbjct: 317 -------GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Query: 360 PSVESH 365
P E +
Sbjct: 370 PQQEGN 375
Score = 35.4 bits (80), Expect = 0.14
Identities = 29/92 (31%), Positives = 35/92 (38%), Gaps = 14/92 (15%)
Query: 239 SKPAKPQPKMKTKSGPVMGGGLP----PPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQA 294
+KP P P K + P GG PP K +GP + Q P P A
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP---------QGPPQQEGNNPQGPPPPA 384
Query: 295 APQPQQVAQPLPAQPPALAQ-PQYQSPQQPPQ 325
PQQ P QP + PQ P +PPQ
Sbjct: 385 GGNPQQPQAPPAGQPQGPPRPPQGGRPSRPPQ 416
>gi|50345881 cytoplasmic polyadenylation element binding protein 3
[Homo sapiens]
Length = 698
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/78 (39%), Positives = 38/78 (48%), Gaps = 5/78 (6%)
Query: 287 QQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGS 346
QQ P P APQP Q AQP AQPP Q +SP P Q + A R+ AA+G S
Sbjct: 164 QQPPPPAPAPQPAQPAQPPQAQPP----QQRRSPASPSQAPY-AQRSAAAAYGHQPIMTS 218
Query: 347 DSNSPGNVQPNSAPSVES 364
+S V +A + S
Sbjct: 219 KPSSSSAVAAAAAAAAAS 236
Score = 35.0 bits (79), Expect = 0.18
Identities = 39/121 (32%), Positives = 50/121 (41%), Gaps = 15/121 (12%)
Query: 254 PVMGGGLPPPPIKHNMDIG---TWDNKGPVPKAPVPQQAPS---PQAAPQPQQVAQPLPA 307
PV GG P IG T ++ P P AP PQ A PQA P Q+ + P+
Sbjct: 145 PVFGGTFSP-------QIGLAQTQHHQQPPPPAPAPQPAQPAQPPQAQPPQQRRSPASPS 197
Query: 308 QPP-ALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQP-NSAPSVESH 365
Q P A QP T + + AA + A S S+S Q N+A S S+
Sbjct: 198 QAPYAQRSAAAAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWNTHQSVNAAWSAPSN 257
Query: 366 P 366
P
Sbjct: 258 P 258
Score = 30.0 bits (66), Expect = 5.8
Identities = 27/96 (28%), Positives = 35/96 (36%), Gaps = 5/96 (5%)
Query: 291 SPQAA-PQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSN 349
SPQ Q Q QP PP PQ P QPPQ + R A+ Q+ A +
Sbjct: 152 SPQIGLAQTQHHQQP----PPPAPAPQPAQPAQPPQAQPPQQRRSPASPSQAPYAQRSAA 207
Query: 350 SPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWN 385
+ QP S + AA + + WN
Sbjct: 208 AAYGHQPIMTSKPSSSSAVAAAAAAAAASSASSSWN 243
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/142 (28%), Positives = 55/142 (38%), Gaps = 23/142 (16%)
Query: 225 NMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP 284
N P PT A+ KP P P + + + +PPPP ++N K PVP P
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNN--------KPPVPSTP 298
Query: 285 VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGA 344
P + S QA P P ++P P P + ++P+ P RN + S
Sbjct: 299 RP--SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP---------QRNLSLSSS--- 344
Query: 345 GSDSNSPGNVQPNSAPSVESHP 366
SPG P P E P
Sbjct: 345 TPPLPSPGRSGPLPPPPSERPP 366
Score = 37.0 bits (84), Expect = 0.048
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 24/122 (19%)
Query: 217 SGNGGT------NVNMPVSKPTSWAAIASKPAKPQPKMK----TKSGPVMGGGL-PPPPI 265
SGN T N+++ S P + S P P P + + P G L PPPP+
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 266 KHNMDIGTWDNKGP-VPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPP 324
N G+ P P+ P SP++ P+P PLP P+ P P PP
Sbjct: 386 SRN---GSTSRALPATPQLPSRSGVDSPRSGPRP-----PLPPDRPSAGAP----PPPPP 433
Query: 325 QT 326
T
Sbjct: 434 ST 435
Score = 35.4 bits (80), Expect = 0.14
Identities = 40/161 (24%), Positives = 59/161 (36%), Gaps = 24/161 (14%)
Query: 241 PAKPQPKMKTK----SGPVMGG------GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
P+ P+P + S PV GG G PPP N GT G + ++P+ +P
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR--GTALGGGSIRQSPLSSSSP 245
Query: 291 ---SPQAAPQPQQVA--QPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAG 345
P P P + +P P PP +P PP P+N +
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP----PPQNNKPPVPSTPRPS 301
Query: 346 SDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNL 386
+ S +P P PS P L + + P+ + NL
Sbjct: 302 ASSQAP---PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 44.3 bits (103), Expect = 3e-04
Identities = 40/142 (28%), Positives = 55/142 (38%), Gaps = 23/142 (16%)
Query: 225 NMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP 284
N P PT A+ KP P P + + + +PPPP ++N K PVP P
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPS-IHREAVPPPPPQNN--------KPPVPSTP 298
Query: 285 VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGA 344
P + S QA P P ++P P P + ++P+ P RN + S
Sbjct: 299 RP--SASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLP---------QRNLSLSSS--- 344
Query: 345 GSDSNSPGNVQPNSAPSVESHP 366
SPG P P E P
Sbjct: 345 TPPLPSPGRSGPLPPPPSERPP 366
Score = 37.0 bits (84), Expect = 0.048
Identities = 36/122 (29%), Positives = 49/122 (40%), Gaps = 24/122 (19%)
Query: 217 SGNGGT------NVNMPVSKPTSWAAIASKPAKPQPKMK----TKSGPVMGGGL-PPPPI 265
SGN T N+++ S P + S P P P + + P G L PPPP+
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 266 KHNMDIGTWDNKGP-VPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPP 324
N G+ P P+ P SP++ P+P PLP P+ P P PP
Sbjct: 386 SRN---GSTSRALPATPQLPSRSGVDSPRSGPRP-----PLPPDRPSAGAP----PPPPP 433
Query: 325 QT 326
T
Sbjct: 434 ST 435
Score = 35.4 bits (80), Expect = 0.14
Identities = 40/161 (24%), Positives = 59/161 (36%), Gaps = 24/161 (14%)
Query: 241 PAKPQPKMKTK----SGPVMGG------GLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAP 290
P+ P+P + S PV GG G PPP N GT G + ++P+ +P
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNR--GTALGGGSIRQSPLSSSSP 245
Query: 291 ---SPQAAPQPQQVA--QPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAG 345
P P P + +P P PP +P PP P+N +
Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPP----PPQNNKPPVPSTPRPS 301
Query: 346 SDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNL 386
+ S +P P PS P L + + P+ + NL
Sbjct: 302 ASSQAP---PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL 339
>gi|190343021 Sec24-related protein D [Homo sapiens]
Length = 1032
Score = 44.3 bits (103), Expect = 3e-04
Identities = 52/212 (24%), Positives = 74/212 (34%), Gaps = 42/212 (19%)
Query: 165 GQPGFHSDTLSKAPGMNSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNV 224
G P ++ S AP S + G +S+S+V +GS +S++ + SG +
Sbjct: 86 GPPPVNNVASSHAPYQPSAQSSYPG----PISTSSVTQLGSQLSAMQINSYGSGMAPPSQ 141
Query: 225 NMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAP 284
P P S ++ + P PQP + V LPPPP N
Sbjct: 142 GPP--GPLSATSLQTPPRPPQPSILQPGSQV----LPPPPTTLN---------------- 179
Query: 285 VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQ---------QPPQTRWVAPRNRN 335
P A+P P + +P P QYQ P PPQ P+
Sbjct: 180 ------GPGASPLPLPMYRPDGLSGPPPPNAQYQPPPLPGQTLGAGYPPQQANSGPQMAG 233
Query: 336 AAFGQSGG-AGSDSNSPGNVQPNSAPSVESHP 366
A GG G + G QP +S P
Sbjct: 234 AQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIP 265
Score = 30.8 bits (68), Expect = 3.4
Identities = 59/239 (24%), Positives = 83/239 (34%), Gaps = 43/239 (17%)
Query: 81 PPIPYLTTYGQLSNGDHHFMHDAV-FGQPGGLGNNIYQHR------FNFFPENPAFSAWG 133
PP P +GQ NG H H F P + N H + +P + S+
Sbjct: 61 PPPPGPHQFGQ--NGAHATGHPPQRFPGPPPVNNVASSHAPYQPSAQSSYPGPISTSSVT 118
Query: 134 TSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSLEQGMVGLKIG 193
GSQ Q ++YGS PPS G PG S T + P
Sbjct: 119 QLGSQLSAMQINSYGSGMA-PPSQ-------GPPGPLSATSLQTPPRPP----------- 159
Query: 194 DVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSG 253
++ GS V T L+G G + + +P+ +P + A+ QP G
Sbjct: 160 ---QPSILQPGSQVLPPPPT-TLNGPGASPLPLPMYRPDGLSGPPPPNAQYQPP--PLPG 213
Query: 254 PVMGGGLPPPPIKHNMDIGTWDNK-------GPVPKA--PVPQQAPSPQAAPQPQQVAQ 303
+G G PP + GP A P PQ+ P + P P QV +
Sbjct: 214 QTLGAGYPPQQANSGPQMAGAQLSYPGGFPGGPAQMAGPPQPQKKLDPDSIPSPIQVIE 272
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/192 (25%), Positives = 74/192 (38%), Gaps = 28/192 (14%)
Query: 191 KIGDVSSSAVKTVGSVVSSVALTGVLSGNG-GTNVNMPVSKPTSWAAIASKPAKPQPKMK 249
K+ + SS + +V SS +L+ S G GT + A+ S PA P P +
Sbjct: 884 KVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLD-------PAVGSPPAPPPPPVP 936
Query: 250 TKSGPVMGGG---LPPPPIKHNMDIGTWDNKGPVPKAPV----PQQAPSPQAAPQPQQVA 302
+ P LPPPP + G+ P+P +PV P +A P +P ++
Sbjct: 937 SPPFPCPADRSPFLPPPPPVTDCSQGS-----PLPHSPVFPPPPPEALIPFCSPPDWCLS 991
Query: 303 QPLPAQPPALAQPQYQSP--------QQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNV 354
P PA P L P +PP + P+ +G +S G++
Sbjct: 992 PPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRPPFTNSGQPESSRGSL 1051
Query: 355 QPNSAPSVESHP 366
+P S S P
Sbjct: 1052 RPPSTKEETSRP 1063
Score = 30.8 bits (68), Expect = 3.4
Identities = 39/159 (24%), Positives = 59/159 (37%), Gaps = 21/159 (13%)
Query: 247 KMKTKSGPVMGGGLPPPPIKHNM--DIGTWDNKG-PVPKAPVPQQA------PSPQAAPQ 297
+M+++S P P P K + D G+ +G PV ++P A PSP P
Sbjct: 1124 EMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEARPSPSTTPL 1183
Query: 298 PQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPN 357
P + P PP +P+ PPQ + N + + G+V
Sbjct: 1184 PD--SSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGEEGSVHSR 1241
Query: 358 SAP--------SVESHPVLEKLK--AAHSYNPKEFEWNL 386
A S +HP L+ AA S +P E N+
Sbjct: 1242 EAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANV 1280
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 43.5 bits (101), Expect = 5e-04
Identities = 33/135 (24%), Positives = 53/135 (39%), Gaps = 17/135 (12%)
Query: 237 IASKPAKPQPKMKTKSGPVMGGGLPPP--PIKHNMDIGTWDNKGPVPKAPVPQQAPSPQA 294
+ KP P + P PPP P++ + G GP K QA +P +
Sbjct: 1237 VVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESK-----QATTPAS 1291
Query: 295 APQPQQVAQP---LPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP 351
+QV+QP +P QPP P+ + P+ P P+ + +S G + +
Sbjct: 1292 RKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPS----EPKKKQPPPPES---GPEQSKQ 1344
Query: 352 GNVQPNSAPSVESHP 366
V P + V+ P
Sbjct: 1345 KKVAPRPSIPVKQKP 1359
Score = 31.6 bits (70), Expect = 2.0
Identities = 32/146 (21%), Positives = 47/146 (32%), Gaps = 16/146 (10%)
Query: 237 IASKPAKPQPKMKTKSGPVMGGG----LPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSP 292
+ P + P + GP +GGG P PP + VP A S
Sbjct: 27 LGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASS 86
Query: 293 QAAPQPQQVAQPLPAQPPAL-AQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSP 351
+A + + P L P + + Q R A FG+SGG G
Sbjct: 87 SSASSSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDE 146
Query: 352 GNV-----------QPNSAPSVESHP 366
+ P +PSV++ P
Sbjct: 147 QFLGFGSDEEVRVRSPTRSPSVKTSP 172
Score = 30.0 bits (66), Expect = 5.8
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 12/132 (9%)
Query: 217 SGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGL----PPPPIKHNMDI- 271
+G + V+ K ++ I S+P P M+T+SG + L PP + ++ I
Sbjct: 724 AGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSIS 783
Query: 272 ------GTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQ 325
+ P + Q S + +P++ PA+P + + P P P
Sbjct: 784 VSPLATSALNPTFTFPSHSLTQSGESAEKNQRPRKQTS-APAEPFSSSSPTPLFPWFTPG 842
Query: 326 TRWVAPRNRNAA 337
++ RN++ A
Sbjct: 843 SQTERGRNKDKA 854
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 43.5 bits (101), Expect = 5e-04
Identities = 48/174 (27%), Positives = 60/174 (34%), Gaps = 29/174 (16%)
Query: 224 VNMPVSKPTSWAAIASKPAKPQPKMKTKSG-------------PVMGGGLPPPPIKHNMD 270
VN P+ P S + P PQP + S P G PP
Sbjct: 803 VNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAP 862
Query: 271 IGTWDNKGPVPKA----PVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQ---- 322
+ T P P++ P P+Q P+P PQQV LPA P A QPQ Q Q
Sbjct: 863 VPTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSA-DQPQQQPRSQQSTA 921
Query: 323 ---PPQTRWVAPRNRNAAFGQSG----GAGSDSNSPGNVQPNSAPSVESHPVLE 369
P T + P Q G S+ S + + NS E P E
Sbjct: 922 ASVPTPTAPLLPPQPATPLSQPAVSIEGQVSNPPSTSSTEVNSQAIAEKQPSQE 975
Score = 36.6 bits (83), Expect = 0.062
Identities = 51/218 (23%), Positives = 76/218 (34%), Gaps = 21/218 (9%)
Query: 170 HSDTLSKAPGMNSLEQGMVGLKIGDVSSSAVKTV-------GSVVSSVALTGVLSGNGGT 222
H L+ AP + G+ LK G VS A++ + S + + +L N
Sbjct: 2021 HGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQL 2080
Query: 223 NVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGT---WDNKGP 279
+ +A +P QP M P GL PP + + + N P
Sbjct: 2081 LAAFIKQRAAKYANSNPQPIPGQPGM-----PQGQPGLQPPTMPGQQGVHSNPAMQNMNP 2135
Query: 280 VPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFG 339
+ Q+A PQ PQ QQ+ P+ P Q P Q R + R +
Sbjct: 2136 MQAGV--QRAGLPQQQPQ-QQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQ 2192
Query: 340 QSGGAGSDSNSPGNVQPN--SAPSVESHPVLEKLKAAH 375
Q GAG PG N P +P ++ + H
Sbjct: 2193 QQQGAG-PGIGPGMANHNQFQQPQGVGYPPQQQQRMQH 2229
Score = 30.8 bits (68), Expect = 3.4
Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 7/62 (11%)
Query: 279 PVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAF 338
P P P P PQ +QP P P ++ P P+T+ P ++ A
Sbjct: 1850 PTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSM-------PPYLPRTQAAGPVSQGKAA 1902
Query: 339 GQ 340
GQ
Sbjct: 1903 GQ 1904
Score = 30.4 bits (67), Expect = 4.5
Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 7/75 (9%)
Query: 279 PVPKAPVPQQAPSPQAAPQPQ------QVAQPLPAQPPALAQPQYQSP-QQPPQTRWVAP 331
P P++ P +PSP+ PQP Q + P P A A P Q P Q ++
Sbjct: 2316 PRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQ 2375
Query: 332 RNRNAAFGQSGGAGS 346
N GA +
Sbjct: 2376 LASNPGMANLHGASA 2390
Score = 30.0 bits (66), Expect = 5.8
Identities = 23/83 (27%), Positives = 30/83 (36%), Gaps = 11/83 (13%)
Query: 285 VPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGA 344
+P P+ P QQ P QP +QPQ P P PR Q+ G
Sbjct: 1847 LPSPTPATPTTPTGQQPTTPQTPQP--TSQPQPTPPNSMPP---YLPRT------QAAGP 1895
Query: 345 GSDSNSPGNVQPNSAPSVESHPV 367
S + G V P + P P+
Sbjct: 1896 VSQGKAAGQVTPPTPPQTAQPPL 1918
Score = 30.0 bits (66), Expect = 5.8
Identities = 15/39 (38%), Positives = 18/39 (46%)
Query: 288 QAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQT 326
Q SPQ P P+ +QP + P QPQ PQT
Sbjct: 2306 QVRSPQPVPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQT 2344
Score = 29.3 bits (64), Expect = 10.0
Identities = 31/138 (22%), Positives = 45/138 (32%), Gaps = 10/138 (7%)
Query: 207 VSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKP------AKPQPKMKTKSGPVMGGGL 260
++S+ TGV+ G P + T + P ++PQP P +
Sbjct: 1832 MASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMPPYLPRTQ 1891
Query: 261 PPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSP 320
P+ G P A P P P A Q+ + Q +Q P
Sbjct: 1892 AAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRP 1951
Query: 321 ---QQPPQTRWVAPRNRN 335
Q PP T +AP N
Sbjct: 1952 IQHQMPPMTP-MAPMGMN 1968
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,559,143
Number of Sequences: 37866
Number of extensions: 1584707
Number of successful extensions: 15005
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 903
Number of HSP's that attempted gapping in prelim test: 8377
Number of HSP's gapped (non-prelim): 4326
length of query: 559
length of database: 18,247,518
effective HSP length: 107
effective length of query: 452
effective length of database: 14,195,856
effective search space: 6416526912
effective search space used: 6416526912
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.