Guide to the Human Genome
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Name: HNF4A Sequence: fasta or formatted (464aa) NCBI GI: 31077207
Description:

hepatocyte nuclear factor 4 alpha isoform a

Referenced in:

Liver
Nuclear Receptors

Other entries for this name:
alt prot [474aa] hepatocyte nuclear factor 4 alpha isoform b
alt prot [417aa] hepatocyte nuclear factor 4 alpha isoform c
alt prot [395aa] hepatocyte nuclear factor 4 alpha isoform f
alt prot [452aa] hepatocyte nuclear factor 4 alpha isoform d
alt prot [442aa] hepatocyte nuclear factor 4 alpha isoform e
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.1         33           2
 C cysteine            2.6         12           1
 D aspartate           6.0         28           2
 E glutamate           5.4         25           1
 F phenylalanine       2.8         13           2
 G glycine             5.8         27           2
 H histidine           2.6         12           2
 I isoleucine          5.8         27           2
 K lysine              5.4         25           2
 L leucine            11.2         52           5
 M methionine          3.4         16           1
 N asparagine          3.7         17           1
 P proline             6.0         28           2
 Q glutamine           5.0         23           1
 R arginine            5.8         27           2
 S serine              8.2         38           2
 T threonine           4.3         20           2
 V valine              5.6         26           2
 W tryptophan          0.4          2           1
 Y tyrosine            2.8         13           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hepatocyte nuclear factor 4 alpha isoform a 
HNF4A                 0.990   hepatocyte nuclear factor 4 alpha isoform b 
HNF4A                 0.919   hepatocyte nuclear factor 4 alpha isoform e 
HNF4A                 0.909   hepatocyte nuclear factor 4 alpha isoform d 
HNF4A                 0.805   hepatocyte nuclear factor 4 alpha isoform c 
HNF4A                 0.724   hepatocyte nuclear factor 4 alpha isoform f 
HNF4G                 0.691   hepatocyte nuclear factor 4, gamma 
RXRA                  0.265   retinoid X receptor, alpha 
RXRB                  0.260   retinoid X receptor, beta 
RXRG                  0.258   retinoid X receptor, gamma isoform a 
NR2F6                 0.225   nuclear receptor subfamily 2, group F, member 6 [Hom...
NR2F2                 0.219   nuclear receptor subfamily 2, group F, member 2 isof...
NR2F1                 0.214   nuclear receptor subfamily 2, group F, member 1 [Homo...
NR2E3                 0.175   photoreceptor-specific nuclear receptor isoform b [Ho...
ESRRB                 0.174   estrogen-related receptor beta 
ESRRG                 0.169   estrogen-related receptor gamma isoform 2 
ESRRG                 0.169   estrogen-related receptor gamma isoform 2 
ESRRG                 0.169   estrogen-related receptor gamma isoform 1 
ESRRG                 0.169   estrogen-related receptor gamma isoform 2 
NR2E1                 0.168   nuclear receptor subfamily 2, group E, member 1 [Homo...
RARB                  0.158   retinoic acid receptor, beta isoform 1 
ESRRA                 0.151   estrogen-related receptor alpha 
RARA                  0.150   retinoic acid receptor, alpha isoform 1 
RARA                  0.150   retinoic acid receptor, alpha isoform 2 
RARA                  0.150   retinoic acid receptor, alpha isoform 1 
RARG                  0.150   retinoic acid receptor, gamma isoform 1 
RARG                  0.149   retinoic acid receptor, gamma isoform 2 
NR2E3                 0.143   photoreceptor-specific nuclear receptor isoform a [Ho...
NR4A2                 0.132   nuclear receptor subfamily 4, group A, member 2 [Homo...
THRB                  0.131   thyroid hormone receptor, beta 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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