BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] (380 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] 783 0.0 gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] 783 0.0 gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] 423 e-118 gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] 384 e-106 gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] 323 2e-88 gi|45007002 longevity assurance homolog 6 [Homo sapiens] 320 1e-87 gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sa... 96 4e-20 gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sa... 93 3e-19 gi|6912450 translocation-associated membrane protein 2 [Homo sap... 60 3e-09 gi|7657655 translocation associated membrane protein 1 [Homo sap... 56 6e-08 gi|145580602 translocation associated membrane protein 1-like 1 ... 45 1e-04 gi|4557861 somatostatin receptor 3 [Homo sapiens] 36 0.050 gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 35 0.15 gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 35 0.15 gi|15375314 LIM homeobox protein 4 [Homo sapiens] 34 0.25 gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 33 0.43 gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens] 33 0.43 gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens] 33 0.43 gi|30410785 LIM homeobox protein 1 [Homo sapiens] 33 0.56 gi|11641283 LIM homeobox protein 5 [Homo sapiens] 33 0.56 gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] 32 0.95 gi|28178843 TG-interacting factor isoform a [Homo sapiens] 32 1.2 gi|4507473 TG-interacting factor isoform c [Homo sapiens] 32 1.2 gi|28178855 TG-interacting factor isoform d [Homo sapiens] 32 1.2 gi|28178853 TG-interacting factor isoform d [Homo sapiens] 32 1.2 gi|28178851 TG-interacting factor isoform d [Homo sapiens] 32 1.2 gi|28178857 TG-interacting factor isoform d [Homo sapiens] 32 1.2 gi|28178849 TG-interacting factor isoform c [Homo sapiens] 32 1.2 gi|28178845 TG-interacting factor isoform b [Homo sapiens] 32 1.2 gi|7662342 zinc fingers and homeoboxes 2 [Homo sapiens] 32 1.2 >gi|32455256 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 783 bits (2021), Expect = 0.0 Identities = 380/380 (100%), Positives = 380/380 (100%) Query: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV Sbjct: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 Query: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR Sbjct: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 Query: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 Query: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 Query: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA 360 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA 360 Query: 361 KSRPLANGHPILNNNHRKND 380 KSRPLANGHPILNNNHRKND Sbjct: 361 KSRPLANGHPILNNNHRKND 380 >gi|31077094 LAG1 longevity assurance 2 [Homo sapiens] Length = 380 Score = 783 bits (2021), Expect = 0.0 Identities = 380/380 (100%), Positives = 380/380 (100%) Query: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV Sbjct: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 Query: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR Sbjct: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY Sbjct: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 Query: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD Sbjct: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 Query: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF Sbjct: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 Query: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA 360 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA Sbjct: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGEEAAAGGGA 360 Query: 361 KSRPLANGHPILNNNHRKND 380 KSRPLANGHPILNNNHRKND Sbjct: 361 KSRPLANGHPILNNNHRKND 380 >gi|116235446 LAG1 longevity assurance homolog 3 [Homo sapiens] Length = 383 Score = 423 bits (1088), Expect = e-118 Identities = 201/382 (52%), Positives = 263/382 (68%), Gaps = 7/382 (1%) Query: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 M T ++FW ER WLP + W+DLED DG V+ K S LY+T+P A L LI+R FE +V Sbjct: 1 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFV 60 Query: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 A+PLA IKE R + PN LE+F+ S +QP Q ++ L+++ L+ RQVERWFR Sbjct: 61 ASPLAKSFGIKETVR-KVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRS 119 Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 RRNQ+RPS LKKF+EA WRF FYL+ +AG+A + DKPW YD+ +VW GYP Q +PSQY Sbjct: 120 RRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQY 179 Query: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 WYY++E+SFYWSLLF + DVKRKDF IIHH+A I L+SFSW ANYIR+GTL+M +HD Sbjct: 180 WYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHD 239 Query: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 +D LESAKMF+YAGW TCN +F +F+ +F I+RL++ PFWIL+CTL+ P+ FF Sbjct: 240 VADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFF 299 Query: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREE-TESSEGEEAAAGGG 359 Y F N + +LQ+LH++W Y IL+M ++ I K ++D RSD E+ E E EE A G Sbjct: 300 SYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKG 359 Query: 360 AKSRPLANG-----HPILNNNH 376 + L NG H I N H Sbjct: 360 KEMDCLKNGLRAERHLIPNGQH 381 >gi|205360977 LAG1 homolog, ceramide synthase 4 [Homo sapiens] Length = 394 Score = 384 bits (985), Expect = e-106 Identities = 184/374 (49%), Positives = 255/374 (68%), Gaps = 10/374 (2%) Query: 1 MLQTLYDYFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 ML + ++FW +R WLP N+TW +LEDRDGRVY DL LPLAL+ L +R FE ++ Sbjct: 1 MLSSFNEWFWQDRFWLPPNVTWTELEDRDGRVYPHPQDLLAALPLALVLLAMRLAFERFI 60 Query: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 PL+ L ++++TR + PNATLE +LT G +PK+ ++ LL+ Q GL+ +Q +RWFRR Sbjct: 61 GLPLSRWLGVRDQTRRQVKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQTQRWFRR 120 Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 RRNQDRP L KKF EASWRF FYL +F+ G++V+ + W + W+ YP Q+ PS Y Sbjct: 121 RRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYHESWLWAPVMCWDRYPNQTLKPSLY 180 Query: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 W+Y++EL FY SLL + DVKRKDFKEQ+IHH +IL++FS+ AN +R G+L++ LHD Sbjct: 181 WWYLLELGFYLSLLIRLPFDVKRKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHD 240 Query: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 SSDYLLE+ KM NY ++ C+ +F++F+ VF TRLV+ P IL+ T + FF Sbjct: 241 SSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTRLVLFPTQILYTTYYESISNRGPFF 300 Query: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHKFI-TGKLVEDERSDREETESSEGEEAA---- 355 GYYFFN ++ +LQLLH+FW+ LILRM + F+ G++ +D RSD EE++SSE AA Sbjct: 301 GYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPL 360 Query: 356 -----AGGGAKSRP 364 A GG + P Sbjct: 361 QLKNGAAGGPRPAP 374 >gi|22218345 LAG1 homolog, ceramide synthase 5 [Homo sapiens] Length = 392 Score = 323 bits (828), Expect = 2e-88 Identities = 157/351 (44%), Positives = 223/351 (63%), Gaps = 2/351 (0%) Query: 2 LQTLYDYFWWERLWLPVNLTWADLED-RDGRVYAKASDLYITLPLALLFLIVRYFFELYV 60 L L+ + W ER WLP N++WADLE DG Y + + PLA VR FE ++ Sbjct: 9 LSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFI 68 Query: 61 ATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRR 120 A P A + I++ +A PNA LE +++ K P + +E LS+Q + R+++ WFR Sbjct: 69 AKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRH 128 Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 RRNQD+P L KF E+ WRFTFYL F G+ + PWF+D+++ W YP Q Y Sbjct: 129 RRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLY 188 Query: 181 WYYMIELSFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHD 240 YY++EL+FYWSL+FS +D+KRKDF +HH+ TI LISFS+ N +R GTLIM LHD Sbjct: 189 HYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHD 248 Query: 241 SSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFF 300 SD+LLE+AK+ NYA ++ C+ +F++F+ VF++TRL I PFWIL+ TL E+ + Sbjct: 249 VSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYA 308 Query: 301 GYYFFNSMMGVLQLLHIFWAYLILRMAHK-FITGKLVEDERSDREETESSE 350 ++ N ++ LQLLH+ W+YLI R+A K I GK+ +D+RSD E + E Sbjct: 309 SWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEE 359 >gi|45007002 longevity assurance homolog 6 [Homo sapiens] Length = 384 Score = 320 bits (820), Expect = 1e-87 Identities = 153/347 (44%), Positives = 225/347 (64%), Gaps = 1/347 (0%) Query: 8 YFWWERLWLPVNLTWADLEDRDGRVYAKASDLYITLPLALLFLIVRYFFELYVATPLAAL 67 +FW ER WLP N+TWADL++ + + +A DLY+ PLA +VR FE +VA P A Sbjct: 7 WFWNERFWLPHNVTWADLKNTEEATFPQAEDLYLAFPLAFCIFMVRLIFERFVAKPCAIA 66 Query: 68 LNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRP 127 LNI+ APPNA LE + K P + +E LS+Q R ++RWFR+RRNQ++P Sbjct: 67 LNIQANGPQIAPPNAILEKVFTAITKHPDEKRLEGLSKQLDWDVRSIQRWFRQRRNQEKP 126 Query: 128 SLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIEL 187 S L +F E+ WRF+FYL F G+ + PW ++ + W YP Q ++YY++EL Sbjct: 127 STLTRFCESMWRFSFYLYVFTYGVRFLKKTPWLWNTRHCWYNYPYQPLTTDLHYYYILEL 186 Query: 188 SFYWSLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLE 247 SFYWSL+FS +D+KRKDF +HH+ +I LI+FS+ N R GTL++ LHDS+D LLE Sbjct: 187 SFYWSLMFSQFTDIKRKDFGIMFLHHLVSIFLITFSYVNNMARVGTLVLCLHDSADALLE 246 Query: 248 SAKMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWILHCTLVYPLELYPAFFGYYFFNS 307 +AKM NYA ++ C+ +F++FA+VFI TRL I P W+L+ TL E+ + ++ FN Sbjct: 247 AAKMANYAKFQKMCDLLFVMFAVVFITTRLGIFPLWVLNTTLFESWEIVGPYPSWWVFNL 306 Query: 308 MMGVLQLLHIFWAYLILRMAHKFIT-GKLVEDERSDREETESSEGEE 353 ++ ++Q L+ FW+YLI+++A K ++ GK+ +D+RSD E + E E Sbjct: 307 LLLLVQGLNCFWSYLIVKIACKAVSRGKVSKDDRSDIESSSDEEDSE 353 >gi|11641421 LAG1 homolog, ceramide synthase 1 isoform 1 [Homo sapiens] Length = 350 Score = 96.3 bits (238), Expect = 4e-20 Identities = 74/256 (28%), Positives = 123/256 (48%), Gaps = 17/256 (6%) Query: 126 RPSLLKKFREASWRFTFYL--IAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWY- 182 +P K E++W+F FYL ++ A + D P+F+D V+ + +P Sbjct: 92 QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151 Query: 183 YMIELSFYW-SLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDS 241 Y+++ SFY S+ ++ D RKD ++HHV T+ILI S+ Y G L++ LHD Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211 Query: 242 SDYLLESAKMFNY----AGWKNTCNNI-----FIVFAIVFIITRLVILPFWILHCTLVYP 292 SD LE K+ Y G + + + + F + RL P +L+ T Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271 Query: 293 LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGE 352 L P Y+FFN+++ +L L++++W I+ A K +TG++ E D E +++E + Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQV--HELKDLREYDTAEAQ 329 Query: 353 EAAAGGGAKSRPLANG 368 K PL NG Sbjct: 330 SLKPSKAEK--PLRNG 343 >gi|38176296 LAG1 homolog, ceramide synthase 1 isoform 2 [Homo sapiens] Length = 337 Score = 93.2 bits (230), Expect = 3e-19 Identities = 69/240 (28%), Positives = 118/240 (49%), Gaps = 15/240 (6%) Query: 126 RPSLLKKFREASWRFTFYL--IAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWY- 182 +P K E++W+F FYL ++ A + D P+F+D V+ + +P Sbjct: 92 QPRDAAKMPESAWKFLFYLGSWSYSAYLLFGTDYPFFHDPPSVFYDWTPGMAVPRDIAAA 151 Query: 183 YMIELSFYW-SLLFSIASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDS 241 Y+++ SFY S+ ++ D RKD ++HHV T+ILI S+ Y G L++ LHD Sbjct: 152 YLLQGSFYGHSIYATLYMDTWRKDSVVMLLHHVVTLILIVSSYAFRYHNVGILVLFLHDI 211 Query: 242 SDYLLESAKMFNY----AGWKNTCNNI-----FIVFAIVFIITRLVILPFWILHCTLVYP 292 SD LE K+ Y G + + + + F + RL P +L+ T Sbjct: 212 SDVQLEFTKLNIYFKSRGGSYHRLHALAADLGCLSFGFSWFWFRLYWFPLKVLYATSHCS 271 Query: 293 LELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITGKLVEDERSDREETESSEGE 352 L P Y+FFN+++ +L L++++W I+ A K +TG++ E D E +++E + Sbjct: 272 LRTVPDIPFYFFFNALLLLLTLMNLYWFLYIVAFAAKVLTGQV--HELKDLREYDTAEAQ 329 >gi|6912450 translocation-associated membrane protein 2 [Homo sapiens] Length = 370 Score = 60.1 bits (144), Expect = 3e-09 Identities = 39/156 (25%), Positives = 82/156 (52%), Gaps = 5/156 (3%) Query: 132 KFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY-WYYMIELSFY 190 KF E+ F+ + I V+V + + + + +WE YP +P Q ++Y+ +L+++ Sbjct: 113 KFNESGQLVVFHFTSVIWCFYVVVTEGYLTNPRSLWEDYP-HVHLPFQVKFFYLCQLAYW 171 Query: 191 WSLLFSI-ASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESA 249 L + V++++ Q+ + ++ I+ ++ N R G +++ L S+++L +A Sbjct: 172 LHALPELYFQKVRKEEIPRQLQYICLYLVHIAGAYLLNLSRLGLILLLLQYSTEFLFHTA 231 Query: 250 KMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWIL 285 ++F +A N +F +A VF +TRL IL +L Sbjct: 232 RLFYFADENN--EKLFSAWAAVFGVTRLFILTLAVL 265 >gi|7657655 translocation associated membrane protein 1 [Homo sapiens] Length = 374 Score = 55.8 bits (133), Expect = 6e-08 Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 5/156 (3%) Query: 132 KFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYW 191 KF E+ FYL A + G +++ + + D +W YP ++Y+ +L+ YW Sbjct: 118 KFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLA-YW 176 Query: 192 SLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESA 249 F K++D Q+++ + I+ ++ N G +++ LH ++L + Sbjct: 177 LHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHIS 236 Query: 250 KMFNYAGWKNTCNNIFIVFAIVFIITRLVILPFWIL 285 ++F ++ K F ++A++F++ RL+ L +L Sbjct: 237 RLFYFSNEK--YQKGFSLWAVLFVLGRLLTLILSVL 270 >gi|145580602 translocation associated membrane protein 1-like 1 [Homo sapiens] Length = 369 Score = 45.1 bits (105), Expect = 1e-04 Identities = 37/162 (22%), Positives = 70/162 (43%), Gaps = 5/162 (3%) Query: 121 RRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVDKPWFYDMKKVWEGYPIQSTIPSQY 180 +R Q + KF E+ FY + I G +++ + D +W+ P Sbjct: 107 KRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMK 166 Query: 181 WYYMIELSFYWSLLFS--IASDVKRKDFKEQIIHHVATIILISFSWFANYIRAGTLIMAL 238 ++Y+ +L+ YW F K++D Q+++ + I+ ++ G L++ L Sbjct: 167 FFYISQLA-YWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVL 225 Query: 239 HDSSDYLLESAKMFNYAGWKNTCNNIFIVFAIVFIITRLVIL 280 H + L +F ++ K ++AIVFI+ RLV L Sbjct: 226 HYFVELLSHMCGLFYFSDEK--YQKGISLWAIVFILGRLVTL 265 >gi|4557861 somatostatin receptor 3 [Homo sapiens] Length = 418 Score = 36.2 bits (82), Expect = 0.050 Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 17/112 (15%) Query: 266 IVFAIVFIITRLVILPFWILHCT-LVYPLELYPAFFGYYFFNSMMGVLQ-----LLHIFW 319 +V A+V + L +PF++L+ +V PL PAFFG YF + +L+ F Sbjct: 258 MVVAVVALFV-LCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFL 316 Query: 320 AY--------LILRMAHKFITGK--LVEDERSDREETESSEGEEAAAGGGAK 361 +Y ++LR + + + + + E+++ E+ E +GEE+ GG K Sbjct: 317 SYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGK 368 >gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] Length = 397 Score = 34.7 bits (78), Expect = 0.15 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 71 KEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 + +T + A TL+ Y TS K + V E LS ++GL R V+ WF+ RR +++ Sbjct: 159 RPRTTITAKQLETLKSAYNTSPKPARHVR-EQLSSETGLDMRVVQVWFQNRRAKEK 213 >gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] Length = 402 Score = 34.7 bits (78), Expect = 0.15 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 71 KEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 + +T + A TL+ Y TS K + V E LS ++GL R V+ WF+ RR +++ Sbjct: 164 RPRTTITAKQLETLKSAYNTSPKPARHVR-EQLSSETGLDMRVVQVWFQNRRAKEK 218 >gi|15375314 LIM homeobox protein 4 [Homo sapiens] Length = 390 Score = 33.9 bits (76), Expect = 0.25 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%) Query: 71 KEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 + +T + A TL++ Y S K + V E LS ++GL R V+ WF+ RR +++ Sbjct: 159 RPRTTITAKQLETLKNAYKNSPKPARHVR-EQLSSETGLDMRVVQVWFQNRRAKEK 213 >gi|126090663 zinc finger homeodomain 4 [Homo sapiens] Length = 3571 Score = 33.1 bits (74), Expect = 0.43 Identities = 14/46 (30%), Positives = 26/46 (56%), Gaps = 6/46 (13%) Query: 88 YLTSGKQPKQVEVELLSRQSGLSGRQVERWFR------RRRNQDRP 127 Y P + +++ ++ +SGLS + ++ WFR R+RN+D P Sbjct: 2102 YFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSP 2147 >gi|28827782 zinc fingers and homeoboxes 3 [Homo sapiens] Length = 956 Score = 33.1 bits (74), Expect = 0.43 Identities = 15/28 (53%), Positives = 20/28 (71%) Query: 95 PKQVEVELLSRQSGLSGRQVERWFRRRR 122 P Q EVE L++ +GLS R+V +WF RR Sbjct: 519 PGQSEVEHLTKVTGLSTREVRKWFSDRR 546 >gi|142976638 sine oculis homeobox homolog 4 [Homo sapiens] Length = 781 Score = 33.1 bits (74), Expect = 0.43 Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 7/56 (12%) Query: 71 KEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 KEK+R NA E + + P E L++ +GLS QV WF+ RR +DR Sbjct: 231 KEKSR-----NALKELY--KQNRYPSPAEKRHLAKITGLSLTQVSNWFKNRRQRDR 279 >gi|30410785 LIM homeobox protein 1 [Homo sapiens] Length = 406 Score = 32.7 bits (73), Expect = 0.56 Identities = 15/54 (27%), Positives = 34/54 (62%), Gaps = 1/54 (1%) Query: 73 KTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 +T ++A TL+ + + K + + E L++++GL+ R ++ WF+ RR+++R Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIR-EQLAQETGLNMRVIQVWFQNRRSKER 236 >gi|11641283 LIM homeobox protein 5 [Homo sapiens] Length = 402 Score = 32.7 bits (73), Expect = 0.56 Identities = 15/54 (27%), Positives = 34/54 (62%), Gaps = 1/54 (1%) Query: 73 KTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDR 126 +T ++A TL+ + + K + + E L++++GL+ R ++ WF+ RR+++R Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIR-EQLAQETGLNMRVIQVWFQNRRSKER 236 >gi|4885597 sine oculis homeobox homolog 3 [Homo sapiens] Length = 332 Score = 32.0 bits (71), Expect = 0.95 Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 7/61 (11%) Query: 71 KEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLL 130 KE+TR + L +YL P + L++ +GL+ QV WF+ RR +DR + Sbjct: 214 KERTR------SLLREWYLQD-PYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAA 266 Query: 131 K 131 K Sbjct: 267 K 267 >gi|28178843 TG-interacting factor isoform a [Homo sapiens] Length = 401 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 185 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 238 >gi|4507473 TG-interacting factor isoform c [Homo sapiens] Length = 272 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 56 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 109 >gi|28178855 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 36 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 89 >gi|28178853 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 36 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 89 >gi|28178851 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 36 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 89 >gi|28178857 TG-interacting factor isoform d [Homo sapiens] Length = 252 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 36 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 89 >gi|28178849 TG-interacting factor isoform c [Homo sapiens] Length = 272 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 56 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 109 >gi|28178845 TG-interacting factor isoform b [Homo sapiens] Length = 286 Score = 31.6 bits (70), Expect = 1.2 Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 85 EHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFT 141 EH Y P + E LLS+Q+ LS QV WF R + P +L+K + +FT Sbjct: 70 EHRY---NAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFT 123 >gi|7662342 zinc fingers and homeoboxes 2 [Homo sapiens] Length = 837 Score = 31.6 bits (70), Expect = 1.2 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 59 YVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQVEVELLSRQSGLSGRQVERWF 118 Y A P A KEKT+ + LE +L S P Q E++ L ++ LS R+++ WF Sbjct: 522 YHAYPDFAPQKFKEKTQGQVK---ILEDSFLKSSF-PTQAELDRLRVETKLSRREIDSWF 577 Query: 119 RRRR 122 RR Sbjct: 578 SERR 581 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.327 0.140 0.450 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,558,048 Number of Sequences: 37866 Number of extensions: 546686 Number of successful extensions: 2809 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 2743 Number of HSP's gapped (non-prelim): 70 length of query: 380 length of database: 18,247,518 effective HSP length: 104 effective length of query: 276 effective length of database: 14,309,454 effective search space: 3949409304 effective search space used: 3949409304 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.