Guide to the Human Genome
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Search of human proteins with 30581111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
sapiens]
         (426 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo ...   849   0.0  
gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo ...   786   0.0  
gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo ...   726   0.0  
gi|30581113 minor histocompatibility antigen 13 isoform 4 [Homo ...   240   2e-63
gi|33413418 signal peptide peptidase 3 [Homo sapiens]                 110   2e-24
gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]           100   3e-21
gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo sap...    93   5e-19
gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo sa...    86   8e-17
gi|38524591 intramembrane protease 5 [Homo sapiens]                    70   4e-12
gi|156105681 presenilin 2 isoform 2 [Homo sapiens]                     33   0.38 
gi|156105679 presenilin 2 isoform 1 [Homo sapiens]                     33   0.38 
gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]                   32   1.1  
gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]                 32   1.1  
gi|91208420 bassoon protein [Homo sapiens]                             32   1.4  
gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]      31   1.9  
gi|4826730 FK506 binding protein 12-rapamycin associated protein...    31   2.4  
gi|17941285 solute carrier family 5 (sodium/glucose cotransporte...    31   2.4  
gi|46276868 hypothetical protein LOC9710 [Homo sapiens]                31   2.4  
gi|195963431 transmembrane protein 201 isoform 1 [Homo sapiens]        30   3.2  
gi|87299628 biorientation of chromosomes in cell division 1-like...    30   4.2  
gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]       30   4.2  
gi|203098098 shroom family member 3 protein [Homo sapiens]             30   5.5  
gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Hom...    29   7.1  
gi|34996489 pleckstrin homology domain interacting protein [Homo...    29   9.3  
gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]                    29   9.3  
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    29   9.3  

>gi|30581111 minor histocompatibility antigen 13 isoform 3 [Homo
           sapiens]
          Length = 426

 Score =  849 bits (2193), Expect = 0.0
 Identities = 426/426 (100%), Positives = 426/426 (100%)

Query: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60
           MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
Sbjct: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60

Query: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120
           KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
Sbjct: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120

Query: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180
           ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
Sbjct: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180

Query: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240
           HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
Sbjct: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240

Query: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300
           KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
Sbjct: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300

Query: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT 360
           GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT
Sbjct: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT 360

Query: 361 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKG 420
           HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKG
Sbjct: 361 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKG 420

Query: 421 LEKKEK 426
           LEKKEK
Sbjct: 421 LEKKEK 426


>gi|30581109 minor histocompatibility antigen 13 isoform 2 [Homo
           sapiens]
          Length = 394

 Score =  786 bits (2030), Expect = 0.0
 Identities = 393/394 (99%), Positives = 394/394 (100%)

Query: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60
           MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
Sbjct: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60

Query: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120
           KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
Sbjct: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120

Query: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180
           ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
Sbjct: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180

Query: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240
           HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
Sbjct: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240

Query: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300
           KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
Sbjct: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300

Query: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT 360
           GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT
Sbjct: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT 360

Query: 361 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAI 394
           HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSA+
Sbjct: 361 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAM 394


>gi|23308607 minor histocompatibility antigen 13 isoform 1 [Homo
           sapiens]
          Length = 377

 Score =  726 bits (1875), Expect = 0.0
 Identities = 376/426 (88%), Positives = 376/426 (88%), Gaps = 49/426 (11%)

Query: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60
           MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
Sbjct: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60

Query: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120
           KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
Sbjct: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120

Query: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180
           ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK
Sbjct: 121 ISPFMNKFFPASFPNRQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRK 180

Query: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240
           HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI
Sbjct: 181 HWIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVFGTNVMVTVAKSFEAPI 240

Query: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300
           KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF
Sbjct: 241 KLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIF 300

Query: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRLT 360
           GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYE S           
Sbjct: 301 GLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYEES----------- 349

Query: 361 HFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASASKG 420
                                                 NPKDPAAVTESKEGTEASASKG
Sbjct: 350 --------------------------------------NPKDPAAVTESKEGTEASASKG 371

Query: 421 LEKKEK 426
           LEKKEK
Sbjct: 372 LEKKEK 377


>gi|30581113 minor histocompatibility antigen 13 isoform 4 [Homo
           sapiens]
          Length = 143

 Score =  240 bits (613), Expect = 2e-63
 Identities = 121/121 (100%), Positives = 121/121 (100%)

Query: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60
           MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG
Sbjct: 1   MDSALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARG 60

Query: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120
           KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT
Sbjct: 61  KNASDMPETITSRDAARFPIIASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHT 120

Query: 121 I 121
           I
Sbjct: 121 I 121


>gi|33413418 signal peptide peptidase 3 [Homo sapiens]
          Length = 384

 Score =  110 bits (275), Expect = 2e-24
 Identities = 98/378 (25%), Positives = 161/378 (42%), Gaps = 97/378 (25%)

Query: 38  SLLLMALLPIFFGALRSVRCA-----------------RGKNASDMPETITSRDAARFPI 80
           S  L+++L I +G+ RS+                     G + ++  +TI S  A   PI
Sbjct: 19  STFLISILLIVYGSFRSLNMDFENQDKEKDSNSSSGSFNGNSTNNSIQTIDSTQALFLPI 78

Query: 81  IASCTLLGLYLFFKIFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPNRQYQL 140
            AS +LL ++ FF     + + ++ ++   VL  +A +  + P               Q 
Sbjct: 79  GASVSLLVMFFFF-----DSVQVVFTICTAVLATIAFAFLLLPMC-------------QY 120

Query: 141 LFTQGSGENKEEIINY----EFDTKDLVCLGLSSIVGVWYLLRKHWIANNLFGLAFSLNG 196
           L    S +NK   I++     F   +L+   LS ++ + ++L  HW+  +   +   +  
Sbjct: 121 LTRPCSPQNK---ISFGCCGRFTAAELLSFSLSVMLVLIWVLTGHWLLMDALAMGLCVAM 177

Query: 197 VELLHLNNVSTGCILLGGLFIYDVFWV------FGTNVMVTVAKS--------------- 235
           +  + L ++   C+LL GL IYDVFWV      F +NVMV VA                 
Sbjct: 178 IAFVRLPSLKVSCLLLSGLLIYDVFWVFFSAYIFNSNVMVKVATQPADNPLDVLSRKLHL 237

Query: 236 ----------FEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFD----- 280
                        P KLVFP          ++F+MLG+GD+V+PG+ +  +LR+D     
Sbjct: 238 GPNVGRDVPRLSLPGKLVFPSS------TGSHFSMLGIGDIVMPGLLLCFVLRYDNYKKQ 291

Query: 281 -------------ISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACI 327
                        IS +    +YF+ +   Y  GL        I + AQPALLYLVP  +
Sbjct: 292 ASGDSCGAPGPANISGRMQKVSYFHCTLIGYFVGLLTATVASRIHRAAQPALLYLVPFTL 351

Query: 328 GFPVLVALAKGEVTEMFS 345
              + +A  KG++  M+S
Sbjct: 352 LPLLTMAYLKGDLRRMWS 369


>gi|21314755 signal peptide peptidase-like 2A [Homo sapiens]
          Length = 520

 Score =  100 bits (248), Expect = 3e-21
 Identities = 86/313 (27%), Positives = 148/313 (47%), Gaps = 47/313 (15%)

Query: 78  FPIIASCTLLGLYLFFK--IFSQEYINLLLSMYFFVLGILALSHTISPFMNKFFPASFPN 135
           F +I    ++ LY F+K  ++    I  + S       + AL H I P+          N
Sbjct: 226 FVVICCVMMVLLYFFYKWLVYVMIAIFCIASAMSLYNCLAALIHKI-PYGQCTIACRGKN 284

Query: 136 RQYQLLFTQGSGENKEEIINYEFDTKDLVCLGLSSIVGVWYLLRKH----WIANNLFGLA 191
            + +L+F  G                  +C+   ++  VW + R      WI  ++ G+A
Sbjct: 285 MEVRLIFLSG------------------LCI---AVAVVWAVFRNEDRWAWILQDILGIA 323

Query: 192 FSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF--------GTNVMVTVA-----KSFEA 238
           F LN ++ L L N  +  ILLG L +YDVF+VF        G ++MV +A      + + 
Sbjct: 324 FCLNLIKTLKLPNFKSCVILLGLLLLYDVFFVFITPFITKNGESIMVELAAGPFGNNEKL 383

Query: 239 PIKLVFPQDLLEKGLEA--NNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFA 296
           P+ +  P+ +    +       ++LG GD+++PG+ IA   RFD+    +++ Y+ +S  
Sbjct: 384 PVVIRVPKLIYFSVMSVCLMPVSILGFGDIIVPGLLIAYCRRFDVQ-TGSSYIYYVSSTV 442

Query: 297 AYIFGLGLTIFIMHIFKHAQPALLYLVPACIGFPVLVALAKGEVTEMFSYESSAEILPHT 356
           AY  G+ LT  ++ + K  QPALLYLVP  +    +VA  + E+ + F   +S +++ H 
Sbjct: 443 AYAIGMILTFVVLVLMKKGQPALLYLVPCTLITASVVAWRRKEM-KKFWKGNSYQMMDHL 501

Query: 357 PRLTH--FPTVSG 367
              T+   P +SG
Sbjct: 502 DCATNEENPVISG 514


>gi|41281782 signal peptide peptidase-like 2B isoform 2 [Homo
           sapiens]
          Length = 592

 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 79/286 (27%), Positives = 130/286 (45%), Gaps = 34/286 (11%)

Query: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218
           L C+ +S    VW + R      W+  +  G+AF L  ++ + L       +LL  LF+Y
Sbjct: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358

Query: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262
           D+F+VF        G+++MV VA          + P+ L  P+ +     L    F++LG
Sbjct: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418

Query: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322
            GD+++PG+ +A   RFDI ++ ++  YF     AY  GL +T   + + +  QPALLYL
Sbjct: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477

Query: 323 VPACIGFPVLVALAKGEVTEMFSYESSAEILPHTPRL------THFPTVSGSPASLADSM 376
           VP  +     VAL + E+   ++    A++LP +P           P  S +P S     
Sbjct: 478 VPCTLVTSCAVALWRRELGVFWTGSGFAKVLPPSPWAPAPADGPQPPKDSATPLSPQPPS 537

Query: 377 QQKLAGPRRRRPQNPSAIYEESNP----KDPAAVTESKEGTEASAS 418
           ++    P        S   EE       ++P +  ES+   +A  S
Sbjct: 538 EEPATSPWPAEQSPKSRTSEEMGAGAPMREPGSPAESEGRDQAQPS 583


>gi|116734691 signal peptide peptidase-like 2B isoform 3 [Homo
           sapiens]
          Length = 511

 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 62/198 (31%), Positives = 100/198 (50%), Gaps = 24/198 (12%)

Query: 163 LVCLGLSSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIY 218
           L C+ +S    VW + R      W+  +  G+AF L  ++ + L       +LL  LF+Y
Sbjct: 302 LFCVAVSV---VWGVFRNEDQWAWVLQDALGIAFCLYMLKTIRLPTFKACTLLLLVLFLY 358

Query: 219 DVFWVF--------GTNVMVTVAKS-------FEAPIKLVFPQ-DLLEKGLEANNFAMLG 262
           D+F+VF        G+++MV VA          + P+ L  P+ +     L    F++LG
Sbjct: 359 DIFFVFITPFLTKSGSSIMVEVATGPSDSATREKLPMVLKVPRLNSSPLALCDRPFSLLG 418

Query: 263 LGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYL 322
            GD+++PG+ +A   RFDI ++ ++  YF     AY  GL +T   + + +  QPALLYL
Sbjct: 419 FGDILVPGLLVAYCHRFDIQVQ-SSRVYFVACTIAYGVGLLVTFVALALMQRGQPALLYL 477

Query: 323 VPACIGFPVLVALAKGEV 340
           VP  +     VAL + E+
Sbjct: 478 VPCTLVTSCAVALWRREL 495


>gi|38524591 intramembrane protease 5 [Homo sapiens]
          Length = 684

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 50/204 (24%), Positives = 90/204 (44%), Gaps = 21/204 (10%)

Query: 169 SSIVGVWYLLRKH----WIANNLFGLAFSLNGVELLHLNNVSTGCILLGGLFIYDVFWVF 224
           ++++  W   R      W+  +  G+++ L  +  + L  +      L  L  +DVF+VF
Sbjct: 332 ATVIIFWVAYRNEDRWAWLLQDTLGISYCLFVLHRVRLPTLKNCSSFLLALLAFDVFFVF 391

Query: 225 GTNVMVTVAKSFEAPIKLVFPQDLLEKGLE----------------ANNFAMLGLGDVVI 268
            T       +S  A + L   +    + L                 +  F++LG GD+V+
Sbjct: 392 VTPFFTKTGESIMAQVALGPAESSSHERLPMVLKVPRLRVSALTLCSQPFSILGFGDIVV 451

Query: 269 PGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALLYLVPACIG 328
           PG  +A   RFD+ +      YF     AY  GL +T   M + +  QPALLYLV + + 
Sbjct: 452 PGFLVAYCCRFDVQVCSR-QIYFVACTVAYAVGLLVTFMAMVLMQMGQPALLYLVSSTLL 510

Query: 329 FPVLVALAKGEVTEMFSYESSAEI 352
             + VA  + E++  ++ +  A++
Sbjct: 511 TSLAVAACRQELSLFWTGQGRAKM 534


>gi|156105681 presenilin 2 isoform 2 [Homo sapiens]
          Length = 447

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 7/84 (8%)

Query: 236 FEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSF 295
           FE P+   +P + LE+  E      LGLGD     IF ++L+    +            F
Sbjct: 339 FEPPLT-GYPGEELEE--EEERGVKLGLGDF----IFYSVLVGKAAATGSGDWNTTLACF 391

Query: 296 AAYIFGLGLTIFIMHIFKHAQPAL 319
            A + GL LT+ ++ +FK A PAL
Sbjct: 392 VAILIGLCLTLLLLAVFKKALPAL 415


>gi|156105679 presenilin 2 isoform 1 [Homo sapiens]
          Length = 448

 Score = 33.5 bits (75), Expect = 0.38
 Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 7/84 (8%)

Query: 236 FEAPIKLVFPQDLLEKGLEANNFAMLGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSF 295
           FE P+   +P + LE+  E      LGLGD     IF ++L+    +            F
Sbjct: 340 FEPPLT-GYPGEELEE--EEERGVKLGLGDF----IFYSVLVGKAAATGSGDWNTTLACF 392

Query: 296 AAYIFGLGLTIFIMHIFKHAQPAL 319
            A + GL LT+ ++ +FK A PAL
Sbjct: 393 VAILIGLCLTLLLLAVFKKALPAL 416


>gi|4506163 presenilin 1 isoform I-467 [Homo sapiens]
          Length = 467

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 381 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 435

Query: 321 YLVPACIGFPVLVALAKGEVTEMF 344
              P  I F ++   A   + + F
Sbjct: 436 ---PISITFGLVFYFATDYLVQPF 456


>gi|195947397 presenilin 1 isoform I-463 [Homo sapiens]
          Length = 463

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)

Query: 261 LGLGDVVIPGIFIALLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQPALL 320
           LGLGD     IF ++L+    +            F A + GL LT+ ++ IFK A PAL 
Sbjct: 377 LGLGDF----IFYSVLVGKASATASGDWNTTIACFVAILIGLCLTLLLLAIFKKALPAL- 431

Query: 321 YLVPACIGFPVLVALAKGEVTEMF 344
              P  I F ++   A   + + F
Sbjct: 432 ---PISITFGLVFYFATDYLVQPF 452


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 17/50 (34%), Positives = 23/50 (46%)

Query: 364 TVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGT 413
           T  G P    +  Q+  A P+RR P N +  YEE  P+  +A      GT
Sbjct: 874 TQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGT 923


>gi|162951873 ventral anterior homeobox 1 isoform a [Homo sapiens]
          Length = 334

 Score = 31.2 bits (69), Expect = 1.9
 Identities = 20/55 (36%), Positives = 27/55 (49%)

Query: 363 PTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAVTESKEGTEASA 417
           P++ GS AS   S    +AG      Q  SA Y  S+  +P + T +KEG E  A
Sbjct: 278 PSLLGSVASRLSSAPLTMAGSLAGNLQELSARYLSSSAFEPYSRTNNKEGAEKKA 332


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
            [Homo sapiens]
          Length = 2549

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 1/69 (1%)

Query: 3    SALSDPHNGSAEAGGPTNSTTRPPSTPEGIALAYGSLLLMALLPIFFGALRSVRCARGKN 62
            +A ++  N  +EA    NS T P    + +       LLM  +P   G  RS+  +RG N
Sbjct: 1841 TASTEGSNSESEAESTENSPT-PSPLQKKVTEDLSKTLLMYTVPAVQGFFRSISLSRGNN 1899

Query: 63   ASDMPETIT 71
              D    +T
Sbjct: 1900 LQDTLRVLT 1908


>gi|17941285 solute carrier family 5 (sodium/glucose cotransporter),
           member 11 [Homo sapiens]
          Length = 675

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 26/91 (28%), Positives = 42/91 (46%), Gaps = 20/91 (21%)

Query: 38  SLLLMA--LLPIFFGALRSVRCARGKNASDMPETITSR-DAARFPIIASCTLLGLYLFFK 94
           S+L++A   LPI+               + MPE +  R    R PII +   L +Y+F K
Sbjct: 108 SVLMLAWIFLPIYIAG----------QVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTK 157

Query: 95  IFSQEYI-------NLLLSMYFFVLGILALS 118
           I    Y        +L L +Y  ++G+LA++
Sbjct: 158 ISVDMYAGAIFIQQSLHLDLYLAIVGLLAIT 188


>gi|46276868 hypothetical protein LOC9710 [Homo sapiens]
          Length = 1070

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 16/41 (39%), Positives = 21/41 (51%)

Query: 351 EILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNP 391
           EILP  P +   P  +   A ++ +MQQK      RRP NP
Sbjct: 833 EILPFDPAVGSDPEFARYVAGVSQAMQQKRQAQHGRRPGNP 873


>gi|195963431 transmembrane protein 201 isoform 1 [Homo sapiens]
          Length = 642

 Score = 30.4 bits (67), Expect = 3.2
 Identities = 49/173 (28%), Positives = 68/173 (39%), Gaps = 30/173 (17%)

Query: 243 VFPQDLLEKGLEANNFAMLGLGDVVIPGIF---IALLLRFDISLKKNTHTYFYTSFAAYI 299
           + P+ + EK  EA  F       VV  G+    +A+LL   I L++     F T   A +
Sbjct: 277 LLPEHMAEKLCEAWAFGQSHQTGVVALGLLTCLLAMLLAGRIRLRRIDA--FCTCLWALL 334

Query: 300 FGLGLTIFIMHIFKHAQPALLYLVP-------ACIGFPVLVALAKGEVTEMFSYE----- 347
            GL L     H+ + A P+ L  +          +GF   VA  K      F        
Sbjct: 335 LGLHLAE--QHL-QAASPSWLDTLKFSTTSLCCLVGFTAAVATRKATGPRRFRPRRFFPG 391

Query: 348 SSAEILPHTPRLT-HFPTVSGSPAS---------LADSMQQKLAGPRRRRPQN 390
            SA + P +P L    P+V GSPAS         L  + QQ    PRR  P +
Sbjct: 392 DSAGLFPTSPSLAIPHPSVGGSPASLFIPSPPSFLPLANQQLFRSPRRTSPSS 444


>gi|87299628 biorientation of chromosomes in cell division 1-like
            [Homo sapiens]
          Length = 3051

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 15/80 (18%), Positives = 36/80 (45%)

Query: 347  ESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPAAV 406
            E     +P   R  H+ +    P    D +  ++   +R+ P+      +E N +D   +
Sbjct: 2762 EEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEEL 2821

Query: 407  TESKEGTEASASKGLEKKEK 426
             ++   T ++ S+ +E+K++
Sbjct: 2822 PKTSSETNSTTSRVMEEKDE 2841


>gi|156523246 proline-rich transmembrane protein 2 [Homo sapiens]
          Length = 340

 Score = 30.0 bits (66), Expect = 4.2
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 16/102 (15%)

Query: 333 VALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRP-QNP 391
           +A +  E++EM   E S ++    P   H    +G P  LA    Q    P   +P  N 
Sbjct: 1   MAASSSEISEMKGVEESPKVPGEGPG--HSEAETGPPQVLAGVPDQ----PEAPQPGPNT 54

Query: 392 SAIYEESNPK---------DPAAVTESKEGTEASASKGLEKK 424
           +A   +S PK          PA  +E+ + T+ S S G E K
Sbjct: 55  TAAPVDSGPKAGLAPETTETPAGASETAQATDLSLSPGGESK 96


>gi|203098098 shroom family member 3 protein [Homo sapiens]
          Length = 1996

 Score = 29.6 bits (65), Expect = 5.5
 Identities = 18/67 (26%), Positives = 25/67 (37%)

Query: 345  SYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRPQNPSAIYEESNPKDPA 404
            S E+SA   PHTPR  H  T +    +       +    RR  P+     Y E    +  
Sbjct: 970  SPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEV 1029

Query: 405  AVTESKE 411
             + E  E
Sbjct: 1030 GIVEEAE 1036


>gi|119392077 Rap guanine nucleotide exchange factor (GEF) 5 [Homo
           sapiens]
          Length = 730

 Score = 29.3 bits (64), Expect = 7.1
 Identities = 36/158 (22%), Positives = 63/158 (39%), Gaps = 24/158 (15%)

Query: 275 LLLRFDISLKKNTHTYFYTSFAAYIFGLGLTIFIMHIFKHAQ------PALLYLVPACIG 328
           LLL   I L  + H YF  ++  Y F      ++   F+  +        LL LVP    
Sbjct: 8   LLLDMGIMLSVDQHLYFQDTYVFYQFSSDECSYLYCEFEREEEWQNGVKLLLQLVPLIPA 67

Query: 329 FPVLVALAKGEVTEMFSYESSAEILPHTPRLTHFPTVSGSPASLADSMQQKLAGPRRRRP 388
              +  L+  ++ +  S ESS EIL                  L  ++Q++LA     + 
Sbjct: 68  RGGICELSHQKIED--SEESSDEIL----------------VRLTSAVQRELAAVIALKA 109

Query: 389 QNPSAIYEESNPKDPAAVTESKEGTEASASKGLEKKEK 426
           +  +   +E N     AVTE++   ++ A    + +E+
Sbjct: 110 RKSAIEQDEENNDKHVAVTEAESVPDSQAGVMCKLQER 147


>gi|34996489 pleckstrin homology domain interacting protein [Homo
           sapiens]
          Length = 1821

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 18/52 (34%), Positives = 27/52 (51%), Gaps = 1/52 (1%)

Query: 346 YESSAEILPHTPRLTHFPTVSGSPASLADSM-QQKLAGPRRRRPQNPSAIYE 396
           ++ SA    H  R    P   GSP S+AD++  +KL G  R     P+A+Y+
Sbjct: 120 WKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQ 171


>gi|21704281 junctophilin 2 isoform 1 [Homo sapiens]
          Length = 696

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 20/71 (28%), Positives = 31/71 (43%), Gaps = 9/71 (12%)

Query: 363 PTVSGSPASLADSMQQKLAGPRRRRPQ---------NPSAIYEESNPKDPAAVTESKEGT 413
           P VSGS ++ +      L  P  R P+          P  I  ++ P+  A  TE++  T
Sbjct: 587 PEVSGSESAPSSPATAPLQAPTLRGPEPARETPAKLEPKPIIPKAEPRAKARKTEARGLT 646

Query: 414 EASASKGLEKK 424
           +A A K   K+
Sbjct: 647 KAGAKKKARKE 657


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 28.9 bits (63), Expect = 9.3
 Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 1/49 (2%)

Query: 362 FPTVSGSPASLADSMQQKLAG-PRRRRPQNPSAIYEESNPKDPAAVTES 409
           + TVS SP +L+   Q          RP +P +I    +P +PA  TES
Sbjct: 656 YSTVSASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATES 704


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,936,346
Number of Sequences: 37866
Number of extensions: 709021
Number of successful extensions: 2507
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 2473
Number of HSP's gapped (non-prelim): 35
length of query: 426
length of database: 18,247,518
effective HSP length: 105
effective length of query: 321
effective length of database: 14,271,588
effective search space: 4581179748
effective search space used: 4581179748
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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