Guide to the Human Genome
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Name: PSEN1 Sequence: fasta or formatted (463aa) NCBI GI: 195947397
Description:

presenilin 1 isoform I-463

Referenced in:

Aspartic Proteases
Notch Pathway

Other entries for this name:
alt prot [467aa] presenilin 1 isoform I-467
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.8         36           2
 C cysteine            1.1          5           1
 D aspartate           4.1         19           2
 E glutamate           6.9         32           3
 F phenylalanine       5.0         23           3
 G glycine             5.0         23           2
 H histidine           2.2         10           1
 I isoleucine          6.7         31           2
 K lysine              3.5         16           2
 L leucine            12.1         56           4
 M methionine          2.8         13           1
 N asparagine          3.7         17           1
 P proline             4.1         19           1
 Q glutamine           3.9         18           2
 R arginine            4.1         19           2
 S serine              7.1         33           3
 T threonine           5.6         26           2
 V valine              8.6         40           4
 W tryptophan          1.7          8           1
 Y tyrosine            4.1         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   presenilin 1 isoform I-463 
PSEN1                 0.993   presenilin 1 isoform I-467 
PSEN2                 0.591   presenilin 2 isoform 1 
PSEN2                 0.588   presenilin 2 isoform 2 
CD47                  0.019   CD47 antigen isoform 3 precursor 
CD47                  0.019   CD47 antigen isoform 2 precursor 
CD47                  0.019   CD47 antigen isoform 1 precursor 
PPP4R1                0.010   protein phosphatase 4, regulatory subunit 1 isoform b...
PPP4R1                0.010   protein phosphatase 4, regulatory subunit 1 isoform...
HM13                  0.008   minor histocompatibility antigen 13 isoform 3 
HM13                  0.008   minor histocompatibility antigen 13 isoform 2 
HM13                  0.008   minor histocompatibility antigen 13 isoform 1 
SUPT5H                0.007   suppressor of Ty 5 homolog isoform b 
SUPT5H                0.007   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.007   suppressor of Ty 5 homolog isoform a 
SUPT5H                0.007   suppressor of Ty 5 homolog isoform a 
ATP11A                0.007   ATPase, class VI, type 11A isoform a 
SPPL2A                0.007   signal peptide peptidase-like 2A 
SLC44A1               0.007   CDW92 antigen 
PPM1G                 0.006   protein phosphatase 1G 
PPM1G                 0.006   protein phosphatase 1G 
GPR89A                0.006   G protein-coupled receptor 89A isoform 1 
GPR89B                0.006   G protein-coupled receptor 89B 
HUWE1                 0.006   HECT, UBA and WWE domain containing 1 
CCDC11                0.006   coiled-coil domain containing 11 
OR13J1                0.006   olfactory receptor, family 13, subfamily J, member 1...
GPR151                0.006   G protein-coupled receptor 151 
PPP1R1B               0.006   protein phosphatase 1, regulatory (inhibitor) subuni...
CHGA                  0.006   chromogranin A precursor 
PPP1R1B               0.006   protein phosphatase 1, regulatory (inhibitor) subuni...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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