Guide to the Human Genome
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Name: PSEN1 Sequence: fasta or formatted (467aa) NCBI GI: 4506163
Description:

presenilin 1 isoform I-467

Referenced in:

Aspartic Proteases
Notch Pathway

Other entries for this name:
alt prot [463aa] presenilin 1 isoform I-463
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.7         36           2
 C cysteine            1.1          5           1
 D aspartate           4.1         19           2
 E glutamate           6.9         32           3
 F phenylalanine       4.9         23           3
 G glycine             4.9         23           2
 H histidine           2.1         10           1
 I isoleucine          6.6         31           2
 K lysine              3.4         16           2
 L leucine            12.0         56           4
 M methionine          2.8         13           1
 N asparagine          3.6         17           1
 P proline             4.1         19           1
 Q glutamine           4.1         19           2
 R arginine            4.3         20           2
 S serine              7.3         34           3
 T threonine           5.6         26           2
 V valine              8.8         41           4
 W tryptophan          1.7          8           1
 Y tyrosine            4.1         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   presenilin 1 isoform I-467 
PSEN1                 0.986   presenilin 1 isoform I-463 
PSEN2                 0.592   presenilin 2 isoform 1 
PSEN2                 0.589   presenilin 2 isoform 2 
CD47                  0.019   CD47 antigen isoform 3 precursor 
CD47                  0.019   CD47 antigen isoform 2 precursor 
CD47                  0.019   CD47 antigen isoform 1 precursor 
PPP4R1                0.010   protein phosphatase 4, regulatory subunit 1 isoform b...
PPP4R1                0.010   protein phosphatase 4, regulatory subunit 1 isoform...
HM13                  0.008   minor histocompatibility antigen 13 isoform 3 
HM13                  0.008   minor histocompatibility antigen 13 isoform 2 
HM13                  0.008   minor histocompatibility antigen 13 isoform 1 
ABCC8                 0.008   ATP-binding cassette, sub-family C, member 8 
COQ9                  0.007   coenzyme Q9 homolog 
CHGA                  0.007   chromogranin A precursor 
ZEB1                  0.007   zinc finger E-box binding homeobox 1 isoform a [Hom...
ZEB1                  0.007   zinc finger E-box binding homeobox 1 isoform b [Hom...
SETD2                 0.007   SET domain containing 2 
ATP11A                0.007   ATPase, class VI, type 11A isoform a 
SPPL2A                0.007   signal peptide peptidase-like 2A 
SLC44A1               0.007   CDW92 antigen 
GPR89A                0.006   G protein-coupled receptor 89A isoform 1 
GPR89B                0.006   G protein-coupled receptor 89B 
CCDC11                0.006   coiled-coil domain containing 11 
ZNF219                0.006   zinc finger protein 219 
ZNF219                0.006   zinc finger protein 219 
OR13J1                0.006   olfactory receptor, family 13, subfamily J, member 1...
ZNF219                0.006   zinc finger protein 219 
GPR151                0.006   G protein-coupled receptor 151 
USH1C                 0.006   harmonin isoform b3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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