Guide to the Human Genome
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Name: PSEN2 Sequence: fasta or formatted (447aa) NCBI GI: 156105681
Description:

presenilin 2 isoform 2

Referenced in:

Aspartic Proteases
Notch Pathway

Other entries for this name:
alt prot [448aa] presenilin 2 isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.0         27           3
 C cysteine            2.0          9           1
 D aspartate           3.8         17           1
 E glutamate           7.8         35           5
 F phenylalanine       4.7         21           1
 G glycine             6.7         30           1
 H histidine           0.9          4           1
 I isoleucine          5.8         26           1
 K lysine              3.4         15           2
 L leucine            13.0         58           4
 M methionine          4.0         18           1
 N asparagine          2.2         10           1
 P proline             6.3         28           2
 Q glutamine           2.7         12           2
 R arginine            2.9         13           1
 S serine              6.5         29           2
 T threonine           6.0         27           2
 V valine              8.5         38           3
 W tryptophan          1.8          8           1
 Y tyrosine            4.9         22           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   presenilin 2 isoform 2 
PSEN2                 0.994   presenilin 2 isoform 1 
PSEN1                 0.605   presenilin 1 isoform I-467 
PSEN1                 0.600   presenilin 1 isoform I-463 
APBB1                 0.014   amyloid beta A4 precursor protein-binding, family B, ...
APBB1                 0.014   amyloid beta A4 precursor protein-binding, family B,...
CD47                  0.013   CD47 antigen isoform 3 precursor 
CD47                  0.013   CD47 antigen isoform 2 precursor 
CD47                  0.013   CD47 antigen isoform 1 precursor 
SCN3A                 0.011   sodium channel, voltage-gated, type III, alpha isof...
SCN3A                 0.011   sodium channel, voltage-gated, type III, alpha isof...
SCN3A                 0.011   sodium channel, voltage-gated, type III, alpha isof...
HM13                  0.009   minor histocompatibility antigen 13 isoform 3 
HM13                  0.009   minor histocompatibility antigen 13 isoform 2 
HM13                  0.009   minor histocompatibility antigen 13 isoform 1 
SCN9A                 0.009   sodium channel, voltage-gated, type IX, alpha 
TERF1                 0.009   telomeric repeat binding factor 1 isoform 1 
TERF1                 0.009   telomeric repeat binding factor 1 isoform 2 
CHIC1                 0.009   cysteine-rich hydrophobic domain 1 
FOXM1                 0.008   forkhead box M1 isoform 3 
FOXM1                 0.008   forkhead box M1 isoform 2 
FOXM1                 0.008   forkhead box M1 isoform 1 
LOC100291562          0.008   PREDICTED: similar to hCG2045708 
LOC100287770          0.008   PREDICTED: similar to hCG2045708 
LOC100287770          0.008   PREDICTED: hypothetical protein XP_002343109 
LOC100132713          0.008   PREDICTED: similar to hCG1654128 
SCN1A                 0.008   sodium channel, voltage-gated, type I, alpha 
SCN2A                 0.008   sodium channel, voltage-gated, type II, alpha isofor...
SCN2A                 0.008   sodium channel, voltage-gated, type II, alpha isofor...
SCN2A                 0.008   sodium channel, voltage-gated, type II, alpha isofor...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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