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Search of human proteins with 29789008
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
(858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29789008 Huntingtin interacting protein C isoform 2 [Homo sap... 1740 0.0
gi|72534686 Huntingtin interacting protein C isoform 1 [Homo sap... 1733 0.0
gi|151301228 formin binding protein 3 [Homo sapiens] 943 0.0
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo... 139 9e-33
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo... 129 9e-30
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 74 4e-13
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 73 1e-12
gi|148746195 trichohyalin [Homo sapiens] 70 8e-12
gi|148727264 transcription elongation regulator 1-like [Homo sap... 68 3e-11
gi|7706501 WW domain binding protein 11 [Homo sapiens] 64 5e-10
gi|146134388 YLP motif containing 1 [Homo sapiens] 64 6e-10
gi|31652264 RNA binding motif protein 26 [Homo sapiens] 63 1e-09
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 61 5e-09
gi|6005948 WW domain-containing binding protein 4 [Homo sapiens] 60 9e-09
gi|4508017 zinc finger protein 207 isoform a [Homo sapiens] 59 1e-08
gi|55749531 splicing factor 3B subunit 2 [Homo sapiens] 59 2e-08
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 58 3e-08
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 58 3e-08
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 58 3e-08
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 58 3e-08
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 58 3e-08
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 58 4e-08
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 58 4e-08
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 58 4e-08
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 58 4e-08
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 58 4e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 57 6e-08
gi|157168329 formin 1 [Homo sapiens] 57 1e-07
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 57 1e-07
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 57 1e-07
>gi|29789008 Huntingtin interacting protein C isoform 2 [Homo
sapiens]
Length = 858
Score = 1740 bits (4507), Expect = 0.0
Identities = 858/858 (100%), Positives = 858/858 (100%)
Query: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM
Sbjct: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL
Sbjct: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
Query: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 180
KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL
Sbjct: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 180
Query: 181 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 240
PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG
Sbjct: 181 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 240
Query: 241 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 300
PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV
Sbjct: 241 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 300
Query: 301 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 360
TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY
Sbjct: 301 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 360
Query: 361 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 420
RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS
Sbjct: 361 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 420
Query: 421 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 480
VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE
Sbjct: 421 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 480
Query: 481 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 540
RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF
Sbjct: 481 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 540
Query: 541 YVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEA 600
YVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEA
Sbjct: 541 YVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEA 600
Query: 601 REREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERI 660
REREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERI
Sbjct: 601 REREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERI 660
Query: 661 RLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKR 720
RLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKR
Sbjct: 661 RLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKR 720
Query: 721 RRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKS 780
RRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKS
Sbjct: 721 RRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKS 780
Query: 781 NSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSE 840
NSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSE
Sbjct: 781 NSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSE 840
Query: 841 GELERRRRTLLQQLDDHQ 858
GELERRRRTLLQQLDDHQ
Sbjct: 841 GELERRRRTLLQQLDDHQ 858
>gi|72534686 Huntingtin interacting protein C isoform 1 [Homo
sapiens]
Length = 871
Score = 1733 bits (4489), Expect = 0.0
Identities = 858/865 (99%), Positives = 858/865 (99%), Gaps = 7/865 (0%)
Query: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM
Sbjct: 7 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 66
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL
Sbjct: 67 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 126
Query: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 180
KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL
Sbjct: 127 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQL 186
Query: 181 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 240
PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG
Sbjct: 187 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 246
Query: 241 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 300
PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV
Sbjct: 247 PSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVV 306
Query: 301 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 360
TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY
Sbjct: 307 TDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRY 366
Query: 361 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 420
RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS
Sbjct: 367 RRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSS 426
Query: 421 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 480
VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE
Sbjct: 427 VNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRE 486
Query: 481 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 540
RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF
Sbjct: 487 RRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKF 546
Query: 541 YVEELKARFHDEKKIIKDILK-------VNTAFEDFAHVISFDKRAAALDAGNIKLTFNS 593
YVEELKARFHDEKKIIKDILK VNTAFEDFAHVISFDKRAAALDAGNIKLTFNS
Sbjct: 547 YVEELKARFHDEKKIIKDILKDRGFCVEVNTAFEDFAHVISFDKRAAALDAGNIKLTFNS 606
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI
Sbjct: 607 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 666
Query: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP
Sbjct: 667 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 726
Query: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT
Sbjct: 727 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 786
Query: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT
Sbjct: 787 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 846
Query: 834 SESELSEGELERRRRTLLQQLDDHQ 858
SESELSEGELERRRRTLLQQLDDHQ
Sbjct: 847 SESELSEGELERRRRTLLQQLDDHQ 871
>gi|151301228 formin binding protein 3 [Homo sapiens]
Length = 930
Score = 943 bits (2437), Expect = 0.0
Identities = 496/928 (53%), Positives = 632/928 (68%), Gaps = 112/928 (12%)
Query: 10 FPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTA 69
+ PMG+ PM QR +PP+P G++P M+PPMG PP + Q+PGM+ +MPGM+M + +
Sbjct: 36 YAPMGMHPMGQRAN-MPPVPHGMMPQMMPPMGGPP-MGQMPGMMSSVMPGMMMSHMSQAS 93
Query: 70 ---ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL 126
A PG ++ A +++W+EH +PDGR YYYN + KQS WEKP LK+ AE
Sbjct: 94 MQPALPPGVNSMDVAAGTASGAKSMWTEHKSPDGRTYYYNTETKQSTWEKPDDLKTPAEQ 153
Query: 127 LLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE------------------VLV 168
LLS+CPWKEYKSD+GKPYYYN+Q+KESRW +PK+L+DLE ++
Sbjct: 154 LLSKCPWKEYKSDSGKPYYYNSQTKESRWAKPKELEDLEGYQNTIVAGSLITKSNLHAMI 213
Query: 169 KQEAAGKQQQQLPQTLQPQPPQPQPDPPP------------------------------- 197
K E + KQ++ + P P P
Sbjct: 214 KAEESSKQEECTTTSTAPVPTTEIPTTMSTMAAAEAAAAVVAAAAAAAAAAAAANANAST 273
Query: 198 ---------VPPGPTPVPTGLLEPEPGGSEDCDVL---EATQPLEQGFLQQLEEGPSSSG 245
VP P P T ++ + +A Q E S++G
Sbjct: 274 SASNTVSGTVPVVPEPEVTSIVATVVDNENTVTISTEEQAQLTSTPAIQDQSVEVSSNTG 333
Query: 246 QHQPQQE--------EEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMK 297
+ +QE +EE + +P + +W+ +E+AKQAFKELL++K VPSNASWEQAMK
Sbjct: 334 EETSKQETVADFTPKKEEEESQPAKKTYTWNTKEEAKQAFKELLKEKRVPSNASWEQAMK 393
Query: 298 MVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTST 357
M++ DPRYSAL KLSEKKQAFNAYK Q EKEEKEEAR + KEAK++ Q FLE HE+MTST
Sbjct: 394 MIINDPRYSALAKLSEKKQAFNAYKVQTEKEEKEEARSKYKEAKESFQRFLENHEKMTST 453
Query: 358 TRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDG 417
TRY++AEQ FGE+EVW + ERDR E+Y+DVLFFL+KKEKEQAKQLR+RN +ALK+ILD
Sbjct: 454 TRYKKAEQMFGEMEVWNAISERDRLEIYEDVLFFLSKKEKEQAKQLRKRNWEALKNILDN 513
Query: 418 MSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERAR 477
M++V + TTWS+AQQYLMDNP+FA+D +LQNMDKEDALICFEEHIRALE+EEEEE++++
Sbjct: 514 MANVTYSTTWSEAQQYLMDNPTFAEDEELQNMDKEDALICFEEHIRALEKEEEEEKQKSL 573
Query: 478 LRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDL 537
LRERR+QRKNRE+FQ FLDELHE GQLHSMS+WMELYP +S+D+RF NMLGQPGST LDL
Sbjct: 574 LRERRRQRKNRESFQIFLDELHEHGQLHSMSSWMELYPTISSDIRFTNMLGQPGSTALDL 633
Query: 538 FKFYVEELKARFHDEKKIIKDILK-------VNTAFEDFAHVISFDKRAAALDAGNIKLT 590
FKFYVE+LKAR+HDEKKIIKDILK VNT FEDF +IS KR+ LDAGNIKL
Sbjct: 634 FKFYVEDLKARYHDEKKIIKDILKDKGFVVEVNTTFEDFVAIISSTKRSTTLDAGNIKLA 693
Query: 591 FNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF 650
FNSLLEKAEAREREREKEEAR+M+R+E+AF+SML+QA P +EL WE++RERFV + AF
Sbjct: 694 FNSLLEKAEAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAF 753
Query: 651 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEEL 710
E ITLESER R+F++F+ VLE ECQH H+K +KH +K KKHH KRS S SGS+S++++
Sbjct: 754 EDITLESERKRIFKDFMHVLEH-ECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDD- 811
Query: 711 PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPK 770
K+R+R+ S S SE SSS +S + +K+KK K
Sbjct: 812 ----SHSKKKRQRSESRSASEHSSSAES---------------------ERSYKKSKKHK 846
Query: 771 KKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTG 830
KK+KKRRHKS+SPES+ + E K+ EK++E +KDR Q++E ++SP K+
Sbjct: 847 KKSKKRRHKSDSPESDAERE----KDKKEKDRESEKDRTRQRSESKHKSPKKKTGKDSGN 902
Query: 831 WDTSESELSEGELERRRRTLLQQLDDHQ 858
WDTS SELSEGELE+RRRTLL+QLDD Q
Sbjct: 903 WDTSGSELSEGELEKRRRTLLEQLDDDQ 930
>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
sapiens]
Length = 1077
Score = 139 bits (351), Expect = 9e-33
Identities = 173/707 (24%), Positives = 290/707 (41%), Gaps = 119/707 (16%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPM-GAPPPLTQI-PGMVPPMMPG 59
P P PP P +P Q AIP PP ++PP P+ G P PL + PGM PP++P
Sbjct: 335 PHPQTLPPAVPHSVP---QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIVP- 390
Query: 60 MLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKP 117
M+ P V + A AT GA S W+E+ DG+ YYYN +S WEKP
Sbjct: 391 MIHPQVAIAASPATLAGATAVSE-----------WTEYKTADGKTYYYNNRTLESTWEKP 439
Query: 118 SVLKSKAELLLS-QCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQ 176
LK K +L + P KE + KE K+ E + ++E A
Sbjct: 440 QELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAA-- 497
Query: 177 QQQLPQTLQPQPPQP---------------------QPDPPPVPPGPTPVPTGLLE-PEP 214
Q+ P P P P D P G V + E P
Sbjct: 498 QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK 557
Query: 215 GGSEDCDVLEATQPL----------------EQGFLQQLEEGPSSSGQHQPQQEEE--ES 256
G E+ L P EQ ++++ E + + + + + +S
Sbjct: 558 KGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDNKDIDS 617
Query: 257 KPEPERSGLSWSNREKA-------KQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSAL- 308
+ E + RE+A + FK++L ++ V + ++WE+ + +V DPRY L
Sbjct: 618 EKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLN 677
Query: 309 PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFG 368
PK E+KQ F+ Y R +EE+ E + + +AK+ + +E+ + T A +
Sbjct: 678 PK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAK 735
Query: 369 ELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWS 428
+ A+ +DR+ ++++ + KKEKE +K R I++ L ++ Q+ WS
Sbjct: 736 DSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGEKIKSDFFELLSNHHLDSQSRWS 794
Query: 429 QAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRALEREEEEERER-----ARLRER- 481
+ + + +P + A D D I E+ + L+ E+E+E ER A LRER
Sbjct: 795 KVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNLDSEKEKELERQARIEASLRERE 852
Query: 482 -----------------RQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFA 524
R+Q K EA Q F L + + +S W + + D R+
Sbjct: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVS-WSDTRRTLRKDHRWE 911
Query: 525 NMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKD---ILKVNTAFEDFAHVISFDKRAAA 581
+ LF ++E L + + + + D + + + +++ +I D R
Sbjct: 912 SGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIK 971
Query: 582 LDAGNIKLTFNSLLEKAEAREREREKEEARRMR--RREAAFRSMLRQ 626
+ + R+++RE EE R + +A FR++L++
Sbjct: 972 FSSSD--------------RKKQREFEEYIRDKYITAKADFRTLLKE 1004
Score = 87.4 bits (215), Expect = 5e-17
Identities = 55/135 (40%), Positives = 67/135 (49%), Gaps = 26/135 (19%)
Query: 2 PPPGI--PPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPGMVP 54
PPP + PPPF M PP RPP PP P +PPM PP G PPP+ Q P +P
Sbjct: 43 PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPPFMP 101
Query: 55 PMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYN 106
P M PGM+ P PVTA P P +W E+ PDG++YYYN
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYN 151
Query: 107 ADDKQSVWEKPSVLK 121
A ++S W KP +K
Sbjct: 152 ARTRESAWTKPDGVK 166
Score = 73.2 bits (178), Expect = 1e-12
Identities = 109/576 (18%), Positives = 217/576 (37%), Gaps = 112/576 (19%)
Query: 82 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 139
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 503 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 562
Query: 140 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 199
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 563 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 612
Query: 200 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 250
+E E + + ++ ++Q LE G S+ + +
Sbjct: 613 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 672
Query: 251 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 298
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 673 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 732
Query: 299 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 351
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 733 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 792
Query: 352 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 396
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 793 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 852
Query: 397 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 441
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 853 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 911
Query: 442 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 501
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 912 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 947
Query: 502 GQLHSMSTWMELYPAVSTDVR--------------FANMLGQPGSTPLDLFKFYVEELKA 547
+ STW E+ + D R F + T F+ ++E K
Sbjct: 948 SAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKF 1007
Query: 548 RFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALD 583
+ KK+I++ + +D ++ DKR LD
Sbjct: 1008 ITYRSKKLIQE---SDQHLKDVEKILQNDKRYLVLD 1040
Score = 67.8 bits (164), Expect = 4e-11
Identities = 55/171 (32%), Positives = 69/171 (40%), Gaps = 59/171 (34%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPP--GILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
PP PPP PP G PP P +PPMPP GI PPM PP PP P P PGM
Sbjct: 59 PP--PPPRPPFGRPPFD---PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
+ P + TAPG PP +E +
Sbjct: 114 MFPP-GMPPVTAPGTPAL--------PP----TEEI------------------------ 136
Query: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQE 171
W E K+ GK YYYN +++ES WT+P D ++V+ + E
Sbjct: 137 ------------WVENKTPDGKVYYYNARTRESAWTKP---DGVKVIQQSE 172
Score = 55.5 bits (132), Expect = 2e-07
Identities = 113/538 (21%), Positives = 213/538 (39%), Gaps = 94/538 (17%)
Query: 178 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSEDCDVLEATQP 228
Q PQTL P P P P PPV PP P+P G+ P PG VL P
Sbjct: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPG------VLPGMAP 386
Query: 229 LEQGFLQQ---LEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKA 285
+ + P++ E E K G ++ + ++ E + +
Sbjct: 387 PIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYNNRTLESTWE--KPQE 441
Query: 286 VPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQREKEEKEEARLRAKEAK 341
+ E+ +K + +P LP +E K++ K + ++EE E A++AK
Sbjct: 442 LKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAK 501
Query: 342 Q---------------TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYD 386
T + + T + + R + G +V ++ E K
Sbjct: 502 PVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHK---- 557
Query: 387 DVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQL 446
K E+ K+LR L + F + + +Q LM+ + + +
Sbjct: 558 --------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEEQELMEEINEDEPVKA 604
Query: 447 QNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 506
+ ++D E A+E E + RERA + + ++ F D L E G + +
Sbjct: 605 KKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ-------FKDMLLERG-VSA 656
Query: 507 MSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAF 566
STW + + D R+ + P + + + + +K R +E++ K+ K+ A
Sbjct: 657 FSTWEKELHKIVFDPRYLLL------NPKERKQVFDQYVKTRAEEERREKKN--KIMQAK 708
Query: 567 EDFAHVIS---FDKRAAALD--AGNIKLTFNSLLEKAEARE----------REREKEEAR 611
EDF ++ F+ RA + A + K + +EK + RE R++EKE+++
Sbjct: 709 EDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK 768
Query: 612 -RMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQ 668
R + ++ F +L L+ + W +V+++ D ++ + S R LF+++++
Sbjct: 769 TRGEKIKSDFFELLSNH--HLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYIE 824
>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
sapiens]
Length = 1098
Score = 129 bits (325), Expect = 9e-30
Identities = 173/729 (23%), Positives = 290/729 (39%), Gaps = 142/729 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPM-GAPPPLTQI----------- 49
P P PP P +P Q AIP PP ++PP P+ G P PL +
Sbjct: 335 PHPQTLPPAVPHSVP---QPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYV 391
Query: 50 -----------PGMVPPMMPGMLMPAVPVTA--ATAPGADTASSAVAGTGPPRALWSEHV 96
PGM PP++P M+ P V + A AT GA S W+E+
Sbjct: 392 KTVATTKTGVLPGMAPPIVP-MIHPQVAIAASPATLAGATAVSE-----------WTEYK 439
Query: 97 APDGRIYYYNADDKQSVWEKPSVL--KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESR 154
DG+ YYYN +S WEKP L K K E + + P KE + KE
Sbjct: 440 TADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKE-PIKEPSEEPLPMETEEEDPKEEP 498
Query: 155 WTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQP---------------------QP 193
K+ E + ++E A Q+ P P P P
Sbjct: 499 IKEIKEEPKEEEMTEEEKAA--QKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMW 556
Query: 194 DPPPVPPGPTPVPTGLLEP-EPGGSEDCDVLEATQPL----------------EQGFLQQ 236
D P G V + EP G E+ L P EQ +++
Sbjct: 557 DRPDDLIGRADVDKIIQEPPHKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEE 616
Query: 237 LEEGPSSSGQHQPQQEEEE--SKPEPERSGLSWSNREKA-------KQAFKELLRDKAVP 287
+ E + + + + ++ S+ E + RE+A + FK++L ++ V
Sbjct: 617 INEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVS 676
Query: 288 SNASWEQAMKMVVTDPRYSAL-PKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQH 346
+ ++WE+ + +V DPRY L PK E+KQ F+ Y R +EE+ E + + +AK+ +
Sbjct: 677 AFSTWEKELHKIVFDPRYLLLNPK--ERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKK 734
Query: 347 FLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRR 406
+E+ + T A + + A+ +DR+ ++++ + KKEKE +K R
Sbjct: 735 MMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSK-TRGE 793
Query: 407 NIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSF-AQDHQLQNMDKEDALICFEEHIRAL 465
I++ L ++ Q+ WS+ + + +P + A D D I E+ + L
Sbjct: 794 KIKSDFFELLSNHHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI--EKIAKNL 851
Query: 466 EREEEEERER-----ARLRER------------------RQQRKNREAFQTFLDELHETG 502
+ E+E+E ER A LRER R+Q K EA Q F L +
Sbjct: 852 DSEKEKELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMV 911
Query: 503 QLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKD---I 559
+ +S W + + D R+ + LF ++E L + + + + D
Sbjct: 912 RSSDVS-WSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSA 970
Query: 560 LKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMR--RRE 617
+ + + +++ +I D R + + R+++RE EE R + +
Sbjct: 971 ITLTSTWKEVKKIIKEDPRCIKFSSSD--------------RKKQREFEEYIRDKYITAK 1016
Query: 618 AAFRSMLRQ 626
A FR++L++
Sbjct: 1017 ADFRTLLKE 1025
Score = 87.4 bits (215), Expect = 5e-17
Identities = 55/135 (40%), Positives = 67/135 (49%), Gaps = 26/135 (19%)
Query: 2 PPPGI--PPPFPPMGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPL----TQIPGMVP 54
PPP + PPPF M PP RPP PP P +PPM PP G PPP+ Q P +P
Sbjct: 43 PPPLMRPPPPFGMMRGPPPPPRPPFGRPPFDPN-MPPMPPPGGIPPPMGPPHLQRPPFMP 101
Query: 55 PMM------PGMLMP--AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYN 106
P M PGM+ P PVTA P P +W E+ PDG++YYYN
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPALP----------PTEEIWVENKTPDGKVYYYN 151
Query: 107 ADDKQSVWEKPSVLK 121
A ++S W KP +K
Sbjct: 152 ARTRESAWTKPDGVK 166
Score = 73.2 bits (178), Expect = 1e-12
Identities = 109/576 (18%), Positives = 217/576 (37%), Gaps = 112/576 (19%)
Query: 82 VAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAEL--LLSQCPWKEYKSD 139
VA P W D R+++YN + S+W++P L +A++ ++ + P K+ +
Sbjct: 524 VATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPPHKKGMEE 583
Query: 140 TGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP 199
K+ R P L + A ++Q+ + + + +P + +
Sbjct: 584 L----------KKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEPVKAKKRKRDDN 633
Query: 200 PGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ--------- 250
+E E + + ++ ++Q LE G S+ + +
Sbjct: 634 KDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPR 693
Query: 251 ------QEEEESKPEPERSGLSWSNREK------AKQAFKELLRDKAVPSNASWEQAMKM 298
+E ++ + ++ REK AK+ FK+++ + A++ +
Sbjct: 694 YLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAK 753
Query: 299 VVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQH------- 351
D R+ A+ K+ +++ FN + A K+EKE+++ R ++ K L H
Sbjct: 754 HAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSNHHLDSQSR 813
Query: 352 -----ERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD----------VLFFLAKKE 396
+++ S RY+ + + +++ E+ K + + + L ++E
Sbjct: 814 WSKVKDKVESDPRYKAVDSSSMREDLFKQYIEKIAKNLDSEKEKELERQARIEASLRERE 873
Query: 397 K-------EQAKQL--------RRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFA 441
+ EQ K++ R IQ K++L M + +WS ++ L + +
Sbjct: 874 REVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVR-SSDVSWSDTRRTLRKDHRWE 932
Query: 442 QDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHET 501
L+ +KE F EHI AL +K RE F+ LD ET
Sbjct: 933 SGSLLEREEKEK---LFNEHIEAL------------------TKKKREHFRQLLD---ET 968
Query: 502 GQLHSMSTWMELYPAVSTDVR--------------FANMLGQPGSTPLDLFKFYVEELKA 547
+ STW E+ + D R F + T F+ ++E K
Sbjct: 969 SAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKF 1028
Query: 548 RFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALD 583
+ KK+I++ + +D ++ DKR LD
Sbjct: 1029 ITYRSKKLIQE---SDQHLKDVEKILQNDKRYLVLD 1061
Score = 67.8 bits (164), Expect = 4e-11
Identities = 55/171 (32%), Positives = 69/171 (40%), Gaps = 59/171 (34%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPP--GILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
PP PPP PP G PP P +PPMPP GI PPM PP PP P P PGM
Sbjct: 59 PP--PPPRPPFGRPPFD---PNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGM 113
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVL 120
+ P + TAPG PP +E +
Sbjct: 114 MFPP-GMPPVTAPGTPAL--------PP----TEEI------------------------ 136
Query: 121 KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQE 171
W E K+ GK YYYN +++ES WT+P D ++V+ + E
Sbjct: 137 ------------WVENKTPDGKVYYYNARTRESAWTKP---DGVKVIQQSE 172
Score = 54.3 bits (129), Expect = 5e-07
Identities = 113/553 (20%), Positives = 216/553 (39%), Gaps = 103/553 (18%)
Query: 178 QQLPQTLQPQPPQPQPDP-------PPV--PPGPTPVPTGLLEPEPGGSE----DCDVLE 224
Q PQTL P P P P PPV PP P+P G+ P PG + C ++
Sbjct: 334 QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLP-GMPIPLPGVAMMQIVSCPYVK 392
Query: 225 ATQPLEQGFLQ--------------QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNR 270
+ G L + P++ E E K G ++
Sbjct: 393 TVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTA---DGKTYYYN 449
Query: 271 EKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSE----KKQAFNAYKAQRE 326
+ ++ E + + + E+ +K + +P LP +E K++ K + +
Sbjct: 450 NRTLESTWE--KPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPK 507
Query: 327 KEEKEEARLRAKEAKQ---------------TLQHFLEQHERMTSTTRYRRAEQTFGELE 371
+EE E A++AK T + + T + + R + G +
Sbjct: 508 EEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRAD 567
Query: 372 VWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQ 431
V ++ E K K E+ K+LR L + F + + +
Sbjct: 568 VDKIIQEPPHK------------KGMEELKKLRHPTPTMLS-----IQKWQFSMSAIKEE 610
Query: 432 QYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAF 491
Q LM+ + + + + ++D E A+E E + RERA + + ++
Sbjct: 611 QELMEEINEDEPVKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQ----- 665
Query: 492 QTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHD 551
F D L E G + + STW + + D R+ + P + + + + +K R +
Sbjct: 666 --FKDMLLERG-VSAFSTWEKELHKIVFDPRYLLL------NPKERKQVFDQYVKTRAEE 716
Query: 552 EKKIIKDILKVNTAFEDFAHVIS---FDKRAAALD--AGNIKLTFNSLLEKAEARE---- 602
E++ K+ K+ A EDF ++ F+ RA + A + K + +EK + RE
Sbjct: 717 ERREKKN--KIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFN 774
Query: 603 ------REREKEEAR-RMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 655
R++EKE+++ R + ++ F +L L+ + W +V+++ D ++ +
Sbjct: 775 EFVAAARKKEKEDSKTRGEKIKSDFFELLSNH--HLDSQSRWSKVKDKVESDPRYKAVDS 832
Query: 656 ESERIRLFREFLQ 668
S R LF+++++
Sbjct: 833 SSMREDLFKQYIE 845
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/121 (26%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Query: 564 TAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSM 623
+ +E H I FD R L+ K F+ + K A E REK+ ++ + + F+ M
Sbjct: 679 STWEKELHKIVFDPRYLLLNPKERKQVFDQYV-KTRAEEERREKKN--KIMQAKEDFKKM 735
Query: 624 LRQAVPALELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGR 683
+ +A + E + DS F+ I +R LF EF+ + E + T+G
Sbjct: 736 MEEA--KFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGE 793
Query: 684 K 684
K
Sbjct: 794 K 794
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 74.3 bits (181), Expect = 4e-13
Identities = 179/832 (21%), Positives = 306/832 (36%), Gaps = 154/832 (18%)
Query: 13 MGLPPMSQRPP-AIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAAT 71
M PP RPP IP +PPGI PP P G PPP+ PG PM+P + P
Sbjct: 1 MSFPPHLNRPPMGIPALPPGIPPPQFP--GFPPPVP--PGT--PMIPVPMSIMAPAPTVL 54
Query: 72 APGADTASSAVAGTGPPRALWS----EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELL 127
P + L + E+ P ++ N +K S +L +K L+
Sbjct: 55 VPTVSMVGKHLGARKDHPGLKAKENDENCGPTTTVFVGNISEKASDMLIRQLL-AKCGLV 113
Query: 128 LSQCPWKEYKSDTGKPYYYN---NQSKESRWTRPKDLDDLEV-----LVKQEAAGKQQQQ 179
LS WK + +GK + + ES + L DL++ LVK +A K + Q
Sbjct: 114 LS---WKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVKVDA--KTKAQ 168
Query: 180 LPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVL-EATQPLEQGFLQQLE 238
L + + G PE ++D + L E T+ +Q +E
Sbjct: 169 LDEWKAKKKAS----------------NGNARPETVTNDDEEALDEETKRRDQMIKGAIE 212
Query: 239 E--GPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAM 296
SS + P QE + S P ++ +EK + F+ +P ++ +
Sbjct: 213 VLIREYSSELNAPSQESD-SHPRKKK-------KEKKEDIFRRFPVAPLIPYPLITKEDI 264
Query: 297 KMVVT--DPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM 354
+ D R ++S+ + + ++ K+EKE + + ++ + E+ R
Sbjct: 265 NAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRE 324
Query: 355 TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI 414
R R E+ E E ER+R+ D +++++ K+ R +
Sbjct: 325 RERERERERER---EKE-----KERERERERD--------RDRDRTKERDRDRDRERDRD 368
Query: 415 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE 474
D S + S++++ D + ++E E R ERE E ERE
Sbjct: 369 RDRERSSDRNKDRSRSREKSRD----------RERERE------RERERERERERERERE 412
Query: 475 RARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANM-LGQPGST 533
R R RER ++R+ + + +E E + R N + + T
Sbjct: 413 REREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKT 472
Query: 534 PLDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNS 593
+ Y +E + +++ K+ ++ ED+ D + K S
Sbjct: 473 -----REYEKEAEREEERRREMAKEAKRLKEFLEDYDD-----------DRDDPKYYRGS 516
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVC------D 647
L+K R+RE+E E R R+RE EL EE+R+R + D
Sbjct: 517 ALQK-RLRDREKEMEADERDRKREKE------------EL----EEIRQRLLAEGHPDPD 559
Query: 648 SAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEE 707
+ +++ E+ER R Q+ ++ E + + K+ ++ P E E
Sbjct: 560 AELQRMEQEAER----RRQPQIKQEPESE--------EEEEEKQEKEEKREEPMEEEEEP 607
Query: 708 EELP--PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRK 765
E+ P P+LRP S SG+ ++ G + SP D +
Sbjct: 608 EQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIIIPHENSP-------DQQQPE 660
Query: 766 AKKPKKKTKKRRHKSNSPESETDPEEKA-------GKESDEKEQEQDKDREL 810
+PK + SNSP + K K DE + + R+L
Sbjct: 661 EHRPKIGLSLKLGASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKL 712
Score = 39.7 bits (91), Expect = 0.012
Identities = 49/239 (20%), Positives = 94/239 (39%), Gaps = 67/239 (28%)
Query: 596 EKAEAREREREKEEA-------RRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDS 648
EK + R+RE ++E+A R++R +EAA++ L+ WE +RER
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN----------WE-IRERKKTRE 474
Query: 649 AFEQITLESERIR-------LFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPS 701
++ E ER R +EFL+ + + +G ++ + +
Sbjct: 475 YEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADER 534
Query: 702 GSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADH 761
+ E+EEL + R+R +E +P + L +E
Sbjct: 535 DRKREKEELE-------EIRQRLLAEGHPDPDAELQRME--------------------- 566
Query: 762 GLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSP 820
++ ++RR E E++ EE+ +E +EK +E +++ E P + P
Sbjct: 567 ---------QEAERRRQPQIKQEPESEEEEEEKQEKEEKREE-----PMEEEEEPEQKP 611
Score = 33.1 bits (74), Expect = 1.1
Identities = 14/49 (28%), Positives = 30/49 (61%)
Query: 764 RKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQ 812
+K K+ ++ K+RR + E E + E+ + E+E+E++K+RE ++
Sbjct: 297 KKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Score = 32.3 bits (72), Expect = 1.9
Identities = 34/168 (20%), Positives = 58/168 (34%), Gaps = 2/168 (1%)
Query: 688 KGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGA-AL 746
KGKK ++ E E E R +R R E E +
Sbjct: 295 KGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRT 354
Query: 747 GGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDK 806
R D ++ K + R KS E E + E + +E E+E+E+++
Sbjct: 355 KERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERER-ERERERER 413
Query: 807 DRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQL 854
+RE ++ R +E+ D E E +L + ++L
Sbjct: 414 EREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERL 461
Score = 32.3 bits (72), Expect = 1.9
Identities = 51/264 (19%), Positives = 103/264 (39%), Gaps = 16/264 (6%)
Query: 596 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 655
E+ REREREKE+ R R R ++ + + RER + +
Sbjct: 326 EREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSR 385
Query: 656 ESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSL 715
E R R RE + E+ E + + R+ R+ ++ + + EE+E
Sbjct: 386 EKSRDR-ERERERERER-EREREREREREREREREREREREREKDKKRDREEDEEDAYER 443
Query: 716 RPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKK 775
R +R+ R + E + + E R + A+ + ++ K+ K+
Sbjct: 444 RKLERKLREKEAAYQERLKNWEIRE--------RKKTREYEKEAEREEERRREMAKEAKR 495
Query: 776 -RRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEK---TGW 831
+ + + DP+ G ++ ++++K+ E + + +++ G
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGH 555
Query: 832 DTSESELS--EGELERRRRTLLQQ 853
++EL E E ERRR+ ++Q
Sbjct: 556 PDPDAELQRMEQEAERRRQPQIKQ 579
Score = 31.2 bits (69), Expect = 4.3
Identities = 13/49 (26%), Positives = 29/49 (59%)
Query: 764 RKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQ 812
+K ++ K K +K R + E + E + +E E+E+E++++RE ++
Sbjct: 289 KKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREK 337
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 73.2 bits (178), Expect = 1e-12
Identities = 75/284 (26%), Positives = 111/284 (39%), Gaps = 42/284 (14%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
P G+PP PP PP PP I P P P +P P L PG +PP P
Sbjct: 792 PEGLPPLPPP---PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPP--P 846
Query: 63 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 122
P VP P G GPP + D + N+ D++ E+ +
Sbjct: 847 PPVPGPVTLPPPQLVPEGTPGGGGPPA------LEEDLTVININSSDEEEEEEEEEEEEE 900
Query: 123 KAELLLSQCPWKEYKSDTGKPYYYNNQSKESRW--------------------TRPKDLD 162
+ E + ++E + D + Y+ + +E + ++L+
Sbjct: 901 EEEEEEEE-DFEEEEEDE-EEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELE 958
Query: 163 DLEVLVKQEAAGKQQQQL--PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSED- 219
++E L A G+ ++ P TL P P P+ PP V P P P P LLE E G+E+
Sbjct: 959 EVEDLEFGTAGGEVEEGAPPPPTLPPALPPPE-SPPKVQPEPEPEPGLLLEVEEPGTEEE 1017
Query: 220 --CDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKP 258
D P QG +++ E P++ Q EEE S P
Sbjct: 1018 RGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP 1061
Score = 59.3 bits (142), Expect = 1e-08
Identities = 77/317 (24%), Positives = 116/317 (36%), Gaps = 64/317 (20%)
Query: 8 PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGM--VPPMMPGMLMPAV 65
PP PMG P P +PP P P PP P P+ + M PM MP+
Sbjct: 636 PPLQPMG--PTCPTPAPVPP-PEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSA 692
Query: 66 PVTAATAPGADTASS----AVAG--TGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSV 119
+ PG T ++ +V G + PPR L P+ N D + P
Sbjct: 693 GPVPSARPGPPTTANHLGLSVPGLVSVPPRLL----PGPENHRAGSNEDPILAPSGTPPP 748
Query: 120 LKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQ--------- 170
E + P + +Y ++ + + D DD V+V +
Sbjct: 749 TIPPDETFGGRVPRPAF------VHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPP 802
Query: 171 --------------------EAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLL 210
A ++ ++LP P PP P P PPPV PGP +P L
Sbjct: 803 PSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPP-PPPPPPPV-PGPVTLPPPQL 860
Query: 211 EPE--PGG------SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPER 262
PE PGG ED V+ E ++ EE + + ++EEE+ + E E
Sbjct: 861 VPEGTPGGGGPPALEEDLTVININSSDE----EEEEEEEEEEEEEEEEEEEEDFEEEEED 916
Query: 263 SGLSWSNREKAKQAFKE 279
+ E+ ++ F+E
Sbjct: 917 EEEYFEEEEEEEEEFEE 933
Score = 33.1 bits (74), Expect = 1.1
Identities = 64/285 (22%), Positives = 92/285 (32%), Gaps = 53/285 (18%)
Query: 581 ALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEV 640
AL+ + NS E+ E E E E+EE E + E EE
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEE-----EEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 641 RERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSP 700
E F + E+ LE E E + LE+ E T
Sbjct: 928 EEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGT-------------------- 967
Query: 701 SGSESEEEELPP----PSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHL 756
+G E EE PP P+L PP+ + E EP L+ E G +
Sbjct: 968 AGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG----------TEEE 1017
Query: 757 LGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESD------EKEQEQDKDREL 810
GAD A + + + SP + P+E +E E+E E D+
Sbjct: 1018 RGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDKVQ 1077
Query: 811 QQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLD 855
E P +E+ +T L E E + L +D
Sbjct: 1078 PPPETP--------AEEEMETETEAEALQEKEQDDTAAMLADFID 1114
Score = 31.2 bits (69), Expect = 4.3
Identities = 27/105 (25%), Positives = 33/105 (31%), Gaps = 20/105 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPP------------------MPPGILPPMLPPMGAP 43
PPP +PP PP PP Q P P P + P LP G
Sbjct: 978 PPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEV 1037
Query: 44 PPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPP 88
+ P PP P L+ P T +T + PP
Sbjct: 1038 EREGESPAAGPP--PQELVEEEPSAPPTLLEEETEDGSDKVQPPP 1080
Score = 30.8 bits (68), Expect = 5.6
Identities = 33/149 (22%), Positives = 55/149 (36%), Gaps = 5/149 (3%)
Query: 712 PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLL--GADHGLRKAKKP 769
PP+ PP + P E + P G P L+ G G
Sbjct: 816 PPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPPALE 875
Query: 770 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQ---EQDKDRELQQAELPNRSPGFGIKK 826
+ T + S+ E E + EE+ +E +E+E+ E+++D E E F +
Sbjct: 876 EDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEF 935
Query: 827 EKTGWDTSESELSEGELERRRRTLLQQLD 855
E+ + E E E E E ++ L+
Sbjct: 936 EEEEGELEEEEEEEDEEEEEELEEVEDLE 964
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 70.1 bits (170), Expect = 8e-12
Identities = 163/792 (20%), Positives = 308/792 (38%), Gaps = 107/792 (13%)
Query: 114 WEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLD-DLEVLVKQEA 172
+ K L+ + E LL + P K + Q +E + ++L + E L+++E
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRR-----------QERERQCREEEELQQEEEQLLREER 1128
Query: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 232
+++Q+L + + + Q + + P LE + E+ Q E+
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEEL------QQEEEQ 1182
Query: 233 FLQQLEEGPSSSGQHQPQQEEE--------ESKPEPERSGLSWSNREKAKQAFKE----- 279
L++ +E + Q ++EEE + E +RS L W + + A ++
Sbjct: 1183 LLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYC 1242
Query: 280 ---------LLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAY--KAQREKE 328
L D + S + ++ + +Q + + Q E+E
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302
Query: 329 EKEEARLR---AKEAKQTLQHFLEQHERMTSTTR-YRRAEQTFGELEVWAVV-PERDRKE 383
E++EA+ R ++E KQ L+ E+ R T R +R EQ E E + ERDRK
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKF 1362
Query: 384 VYDDVLFF-LAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQ 442
+++ +K E+ ++LRR+ + + L + Q Q +Q D +
Sbjct: 1363 REEELRHQEQGRKFLEEEQRLRRQERE--RKFLKEEQQLRCQEREQQLRQD-RDRKFREE 1419
Query: 443 DHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETG 502
+ QL +++ E+ +R ERE + E +LR+ R RK RE Q L + E
Sbjct: 1420 EQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQER-HRKFREEEQ--LLQEREEQ 1476
Query: 503 QLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKV 562
QLH D +F Q D KF +EL+++ E+K +++ ++
Sbjct: 1477 QLHRQ----------ERDRKFLEEEQQLRRQERDR-KFREQELRSQ-EPERKFLEEEQQL 1524
Query: 563 NTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRS 622
+ + + +++ + G ++ + R+R+ +EE R R E
Sbjct: 1525 HRQ-QRQRKFLQEEQQLRRQERGQ---------QRRQDRDRKFREEEQLRQEREEQQLSR 1574
Query: 623 MLRQAVPALELGTAWEEVRERFVCDSAFE------QITLESERIRLFREFLQVLEQTECQ 676
R LE + +ER + + Q L ER R FRE Q+L++ E Q
Sbjct: 1575 QERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Query: 677 HLHTKGR-------KHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESG 729
LH + R + + ++ + H EEE+L RR+ +
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 730 SEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDP 789
E R L + LR+ + +K ++ + + + + +
Sbjct: 1695 EEEQQL------------RRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRR 1742
Query: 790 EEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRR- 848
+E+ K +E++ +RE QQ R F ++E+ + E +L E +R+ R
Sbjct: 1743 QERYRKILEEEQLR--PEREEQQLRRQERDRKFR-EEEQLRQEREEQQLRSQESDRKFRE 1799
Query: 849 --TLLQQLDDHQ 858
L Q+ ++ Q
Sbjct: 1800 EEQLRQEREEQQ 1811
Score = 65.9 bits (159), Expect = 2e-10
Identities = 125/640 (19%), Positives = 249/640 (38%), Gaps = 50/640 (7%)
Query: 234 LQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWE 293
L++ +E +H+ ++ E+ K E E W RE+ + ++ R +
Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERR-DWLKREEETERHEQERR----------K 473
Query: 294 QAMKMVVTDPRYSALPKLSEKK----QAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLE 349
Q +K + R KL E++ Q + +RE+EE+ E RL+ +E ++ LQ L
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 350 QHERMTSTTRYRRAEQTFGELEVWAVVPERDR--KEVYDDVLFFLAKKEKEQAKQ-LRRR 406
+++ RR + E E R++ K ++ L K+E+E+ +Q L+R
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 407 NIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKED-------ALICFE 459
+ L+ L + + Q+ + P + QL ++++ E
Sbjct: 594 QEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE 653
Query: 460 EHIRALEREEEEERERARL-RERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVS 518
+ L+REEEEER RL RE ++R+ +E + ++ E ++ S +
Sbjct: 654 RREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE--RIKSRIPKWQWQLESE 711
Query: 519 TDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKR 578
D R + + +P E + R E+K + ++ E+ AH R
Sbjct: 712 ADARQSKVYSRPRKQ---------EGQRRRQEQEEKRRRRESELQWQEEERAH------R 756
Query: 579 AAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWE 638
+ T+ E+ R R+R +RE R+ RQ L E
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 639 -EVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRS 697
E R R + E LE E RE Q L++ E + R+ ++ ++ R
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRW 876
Query: 698 HSPSGSESEEEEL-PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHL 756
+ L P+L+ R+ + + E + + + L
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936
Query: 757 LGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELP 816
+ L + ++ K++ ++R + + EE+ E EK + Q+++++ ++ E
Sbjct: 937 QQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEEL 996
Query: 817 NRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLDD 856
+ +++E+ + E E + R++ LQQ ++
Sbjct: 997 QQEEEQLLREER-----EKRRRQEWERQYRKKDELQQEEE 1031
Score = 65.1 bits (157), Expect = 3e-10
Identities = 129/636 (20%), Positives = 255/636 (40%), Gaps = 98/636 (15%)
Query: 248 QPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSA 307
Q +++E+E K S L W E+A + +E ++ W+ K R SA
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQE--EEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 308 LPKLSEKKQA-FNAYKAQR-------EKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTR 359
P L E+++ A + Q+ E+EEKE+ R + +E ++ LQ FLE+ E++ R
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ-FLEEEEQLQ---R 842
Query: 360 YRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMS 419
RA+Q E + + +++R+ + + + E+ ++ RR + A ++
Sbjct: 843 RERAQQLQEEED--GLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPAL----- 895
Query: 420 SVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLR 479
Q + QQ L + Q + + +++ + E L++EEE+ R +
Sbjct: 896 ----QEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREE-EQLQQEEEQLLREEREK 950
Query: 480 ERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFK 539
RRQ+R+ + L + E +LG+ K
Sbjct: 951 RRRQERERQYRKDKKLQQKEE------------------------QLLGEEPE------K 980
Query: 540 FYVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLL---- 595
+E + ++ +E+++ ++ ++ + ++++ D ++ LL
Sbjct: 981 RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD--ELQQEEEQLLREER 1038
Query: 596 EKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQITL 655
EK +ERER+ E +++ E R+ EL + + E EQ+
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE---LQQEEEQLLR 1095
Query: 656 E-------SERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEE 708
E ER R RE + L+Q E Q L + K R+ + ++ + EEE
Sbjct: 1096 EEPEKRRRQERERQCRE-EEELQQEEEQLLREEREKRRRQELERQYREEEE---VQQEEE 1151
Query: 709 ELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKK 768
+L P++RRR E L E R + R+ ++
Sbjct: 1152 QL---LREEPEKRRRQELERQYREEEELQQEEEQLL----REEQEKRRQERERQYREEEE 1204
Query: 769 PKKKTKKRRHKSNSPESET----DPEEKAGKESDE---KEQEQDKDRELQQAELPNRSPG 821
+++ +K+R++ S+ +PE++ ++ K +E ++ R+L+ ++L +R
Sbjct: 1205 LQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQ-- 1262
Query: 822 FGIKKEKTGWDTSESELSEGELERRRRTLLQQLDDH 857
++ E + + E ERRR QQ D H
Sbjct: 1263 ---SQQDLQHLLGEQQERDREQERRR---WQQRDRH 1292
Score = 62.4 bits (150), Expect = 2e-09
Identities = 119/621 (19%), Positives = 248/621 (39%), Gaps = 55/621 (8%)
Query: 246 QHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRY 305
+H P++E+ E + + E R++ Q K+LLR++ E+ + TD ++
Sbjct: 1291 RHFPEEEQLEREEQKEAK-----RRDRKSQEEKQLLREER-------EEKRRRQETDRKF 1338
Query: 306 SALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQ 365
+L ++++ + +R+++ +EE ++ ++ FLE+ +R+ R + E+
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK----FLEEEQRL----RRQERER 1390
Query: 366 TFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQT 425
F + E ER+++ D F ++E++ ++Q R R + + + +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKF-REEEQQLSRQERDRKFREEEQQVRRQER---ER 1446
Query: 426 TWSQAQQYLMD--NPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERERARLRERRQ 483
+ + +Q L + F ++ QL +E L E + LE E++ R+ + R Q
Sbjct: 1447 KFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ 1506
Query: 484 QRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVE 543
+ +++E + FL+E + + +++ + R GQ D KF E
Sbjct: 1507 ELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQER-----GQQRRQDRDR-KFREE 1560
Query: 544 ELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEARER 603
E + +E+++ + E+ +R D ++ + E +
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 604 EREKEEARRMRRREAAFRS----MLRQAVPALELGTAWEEVR---------ERFVCDSAF 650
RE E+ + R + R + P L +++R E +
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGE 1680
Query: 651 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEEL 710
EQ ER R FRE Q L + E + + + R+ + R E+E+E+L
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 711 PPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPK 770
R +R R+ E P + R + LR + +
Sbjct: 1741 -----RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 771 KKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRE---LQQAELPNRSPGFGIKKE 827
K ++ + + E + P+++ GK E+EQ Q +++E Q+ + R+ +E
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 828 KTGWDTSESELSEGELERRRR 848
K+ E EL + E ++RR+
Sbjct: 1856 KS--RREEQELWQEEEQKRRQ 1874
Score = 57.0 bits (136), Expect = 7e-08
Identities = 122/658 (18%), Positives = 256/658 (38%), Gaps = 58/658 (8%)
Query: 223 LEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELL- 281
L+ +P Q LQ+ EE + + ++E +E + + +R R K ++ +E
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE 319
Query: 282 -----RDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 336
+++ EQ ++ + R L + E+++ + ++E+E +E+ R
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 337 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKE 396
++ ++ Q L + +++ + RR +Q E ++ R+++ + L ++E
Sbjct: 380 EQQLRREQQ--LRREQQLRREQQLRREQQLRREQQL-----RREQQLRREQQLRREQEEE 432
Query: 397 KEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQL---QNMDKED 453
+ + K + R Q LK + + W + ++ + + QL Q ++ +
Sbjct: 433 RHEQKHEQERREQRLKREQEE------RRDWLKREEETERHEQERRKQQLKRDQEEERRE 486
Query: 454 ALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDEL--------HETGQLH 505
+ EE R ++E E++ R ERR+QR R+ + L + E +
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 506 SMSTWMELYPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTA 565
E + + R + + L K E + R E++ + L+
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE---ERLEQRLK 603
Query: 566 FEDFAHVISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLR 625
E+ + ++R L + L K+E +E ER +++ RR ++ R
Sbjct: 604 REEVERLEQEERREQRLKREEPEEERRQQLLKSEEQE-ERRQQQLRREQQERREQRLKRE 662
Query: 626 QAVPALELGTAWEEVRERFVCDSAFEQITLESERI--RLFREFLQVLEQTECQHLHTKGR 683
+ LE E ER + A E+ ERI R+ + Q+ + + + R
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSR 722
Query: 684 KHGRKGKKHHHKRSHSPSGSESE----EEELPPPSLRPPKRRRRNPSESGSEPSSSLDSV 739
++G++ ++ ESE EEE + ++RR + +E S
Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS----- 777
Query: 740 ESGGAALGGRG---SPSSHLLGADHGLRKAKK----PKKKTKKRRHKSNSPESETDPEEK 792
E G L R L A+ ++ ++ ++K ++RR + + EE+
Sbjct: 778 ERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Query: 793 AGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTL 850
+ E+ Q+ ++ + Q + R + +K W E E +RRR TL
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE------ERKRRRHTL 889
Score = 50.4 bits (119), Expect = 7e-06
Identities = 117/581 (20%), Positives = 221/581 (38%), Gaps = 86/581 (14%)
Query: 238 EEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMK 297
E+ S G + +EE E L RE+ +Q +E R V ++ K
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRE--RQDRVFQEEEEKEWRK 248
Query: 298 MVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEAR-LRAKEAKQTLQHFLEQHERMTS 356
R + L K EK Q + + +EE+E+ R L +E ++ Q +Q +R+
Sbjct: 249 ------RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRR 302
Query: 357 TTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAK--QLRRRNIQALKSI 414
+ RR ++ + +++R+E ++ ++E+E+ + QLRR + +
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERRE- 361
Query: 415 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEERE 474
+ + + +Q L ++ QL + + + E+ +R ++ E++
Sbjct: 362 ----QQLRREQEEERREQQLRREQQLRREQQL----RREQQLRREQQLRREQQLRREQQL 413
Query: 475 RARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQPGSTP 534
R + RR+Q+ RE + ++ HE R L +
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHE-------------------QERREQRLKREQEER 454
Query: 535 LDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLTFNSL 594
D K EE R E++ K LK + E +R L KL
Sbjct: 455 RDWLK--REEETERHEQERR--KQQLKRDQEEE---------RRERWL-----KLEEEER 496
Query: 595 LEKAEARERE--REKEEARRMRRREAAFRSMLRQAVPA-LELGTAWEEVRERFVCDSAFE 651
E+ E RE++ RE+EE R R + L+Q + + +L EE RE+ + +
Sbjct: 497 REQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEK 556
Query: 652 QITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELP 711
++ E RL RE E+ Q L + + ++ K+ +R E E E L
Sbjct: 557 RLEQERREQRLKRE----QEERRDQLLKREEERRQQRLKREQEERLEQRLKRE-EVERLE 611
Query: 712 PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKK 771
R + +R P E + + E R+ + ++
Sbjct: 612 QEERREQRLKREEPEEERRQQLLKSEEQEE---------------------RRQQQLRRE 650
Query: 772 KTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQ 812
+ ++R + E E E++ +E +E+ +EQ+ E Q+
Sbjct: 651 QQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Score = 49.3 bits (116), Expect = 2e-05
Identities = 106/567 (18%), Positives = 210/567 (37%), Gaps = 87/567 (15%)
Query: 313 EKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQ---HERMTSTTRYRRAEQTFGE 369
E ++ F Q E+E + R + +E ++ L EQ ER+ R RR E+ + +
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 370 LEVWAVVPERDRKEVYDDVLFFLAKKEKEQ---AKQLRRRNI------------QALKSI 414
+ W ER+ + ++ L E E+ +QLRRR + Q +
Sbjct: 177 RQEWQ---EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRER 233
Query: 415 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNM----DKEDALICFEEHIRALEREEE 470
D + + W + + L Q+ + Q ++E+ L E ER+EE
Sbjct: 234 QDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE 293
Query: 471 EERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMELYPAVSTDVRFANMLGQP 530
E++++ RE++ +RK E + +E E + Q
Sbjct: 294 EQQQQRLRREQQLRRKQEEERREQQEERREQQERREQ---------------------QE 332
Query: 531 GSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHVISFDKRAAALDAGNIKLT 590
L + E + + E++ + ++ E+ ++R L
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEE-------ERREQQLRREQQLRR 385
Query: 591 FNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAF 650
L + + R ++ + E + R ++ LR+ +L EE R +
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR---EQQLRREQEEERHEQKHEQER 442
Query: 651 EQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSES----E 706
+ L+ E+ R++L+ E+TE +H ++ +K KR E E
Sbjct: 443 REQRLKREQEER-RDWLKREEETE---------RHEQERRKQQLKRDQEEERRERWLKLE 492
Query: 707 EEELPPPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKA 766
EEE R ++ RR E + + E LR
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEER-----------------LQQRLRSE 535
Query: 767 KKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKK 826
++ +++ ++RR + E E E++ ++ ++EQE+ +D+ L++ E + ++
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 827 EKTGWDTSESELSEGELERRRRTLLQQ 853
E+ E+ E E RR L++
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKR 622
Score = 45.4 bits (106), Expect = 2e-04
Identities = 114/597 (19%), Positives = 221/597 (37%), Gaps = 96/597 (16%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKE---L 280
E Q EQ FL + EE Q + +++E + E E+ RE+A+Q +E L
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQL----QRRERAQQLQEEEDGL 856
Query: 281 LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEA 340
D+ + + K R+ + ++ A A +E+ KE+ L+ +E
Sbjct: 857 QEDQERRRSQEQRRDQKW-----RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE- 910
Query: 341 KQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQA 400
+ LQ + R R R E+ + E + ER+++ + +++ +
Sbjct: 911 -EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE------RERQYRKD 963
Query: 401 KQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEE 460
K+L+++ Q L + + + + ++ + ++ + + +E +E
Sbjct: 964 KKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE-----WER 1018
Query: 461 HIRA---LEREEE----EERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMEL 513
R L++EEE EERE+ RL+ER +Q + E Q ++L
Sbjct: 1019 QYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL--------------- 1063
Query: 514 YPAVSTDVRFANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHVI 573
LG+ T +EL+ ++ E+++ ++ + E+
Sbjct: 1064 -------------LGEERETRRR------QELERQYRKEEELQQE--EEQLLREEPEKRR 1102
Query: 574 SFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFR---SMLRQAVPA 630
++ + ++ LL E RE+ R +E R+ R E + +LR+
Sbjct: 1103 RQERERQCREEEELQQEEEQLLR--EEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160
Query: 631 LELGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGK 690
+ RE EQ+ E + R Q E+ E Q R+ +
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQ----------RQKR 1210
Query: 691 KHHHKRSHSPSGSESEEEELPPPSLRPPK---RRRRNPSESGSEPSSSLDSVESGGAALG 747
K ++ S + + E ++R K + R N E S D
Sbjct: 1211 KQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ------ 1264
Query: 748 GRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQ 804
HLLG + ++ ++ ++ RH + E + E+K K D K QE+
Sbjct: 1265 ---QDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE-EQKEAKRRDRKSQEE 1317
Score = 43.1 bits (100), Expect = 0.001
Identities = 53/269 (19%), Positives = 117/269 (43%), Gaps = 32/269 (11%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 283
E Q L++G QQL + ++E++ + E ER L + + ++ ++ +
Sbjct: 1671 EEEQLLQEGEEQQLRR--QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREE 1728
Query: 284 KAVPSNASWEQAMKMVVTDPRYSAL---PKLSEKKQAFNAYKAQREKEEKEEARLRAKEA 340
+ + EQ + RY + +L +++ + +R+++ +EE +LR +
Sbjct: 1729 EQLRQETEQEQLRRQ----ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE 1784
Query: 341 KQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPE-RDRKEVYDDVLFFLAKKEKEQ 399
+Q L+ S ++R EQ E E + P+ RD K +++ L ++E ++
Sbjct: 1785 EQQLRS-------QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE-QR 1836
Query: 400 AKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFE 459
+Q R R +A + +Q + + + ++ Q + ++E L E
Sbjct: 1837 LRQERDRQYRAEEQFA------------TQEKSRREEQELWQEEEQKRRQERERKLR--E 1882
Query: 460 EHIRALEREEEEERERARLRERRQQRKNR 488
EHIR ++EE+ R+ ++ + + R
Sbjct: 1883 EHIRRQQKEEQRHRQVGEIKSQEGKGHGR 1911
Score = 39.7 bits (91), Expect = 0.012
Identities = 62/283 (21%), Positives = 114/283 (40%), Gaps = 38/283 (13%)
Query: 237 LEEGPSSSGQHQPQQ----------EEEESKPEPERSGLSWSNRE-KAKQAFKELLRDKA 285
LEE P Q + QQ EEE+ E E L R+ K ++ ++L R +
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705
Query: 286 VPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQ 345
EQ ++ + ++ +L ++ + + +R ++ EE +LR + +Q L+
Sbjct: 1706 ERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 346 HFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRR 405
R ++R EQ E E E+ + D F +E+EQ +Q R
Sbjct: 1766 -------RQERDRKFREEEQLRQERE------EQQLRSQESDRKF----REEEQLRQERE 1808
Query: 406 RNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRAL 465
Q DG + W + Q L + + + + E+ +E R
Sbjct: 1809 EQ-QLRPQQRDG------KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-QEKSRRE 1860
Query: 466 ERE--EEEERERARLRERRQQRKNREAFQTFLDELHETGQLHS 506
E+E +EEE++R + RER+ + ++ Q + G++ S
Sbjct: 1861 EQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
Score = 39.3 bits (90), Expect = 0.016
Identities = 52/260 (20%), Positives = 106/260 (40%), Gaps = 49/260 (18%)
Query: 235 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQ 294
+QLEE P + + Q++E E E+S +E+ +Q RD+ W Q
Sbjct: 127 RQLEEEPGQRRRQKRQEQERELAEGEEQS----EKQERLEQ------RDRQRRDEELWRQ 176
Query: 295 AMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERM 354
+ + R + +++ + K +E +E +LR +E + + E+ ++
Sbjct: 177 RQEWQEREERRA-------EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 355 TSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLRRRNIQALKSI 414
R R ++ F E E E ++E + +KE+E+ ++ + + L+
Sbjct: 230 ----RRERQDRVFQEEEE----KEWRKRET-------VLRKEEEKLQEEEPQRQRELQEE 274
Query: 415 LDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEER- 473
+ + + Q + Q+ ++ QL+ +E+ RE++EER
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEE------------RREQQEERR 322
Query: 474 ----ERARLRERRQQRKNRE 489
R + ERR+Q+ RE
Sbjct: 323 EQQERREQQEERREQQLRRE 342
Score = 36.2 bits (82), Expect = 0.13
Identities = 52/291 (17%), Positives = 121/291 (41%), Gaps = 19/291 (6%)
Query: 227 QPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAF-KELLRDKA 285
Q E+ F++ ++ GQ Q +QE + E E+ ++ +Q ++ L ++
Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Query: 286 VPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKE-EKEEARLRAKEAKQTL 344
EQ ++ D ++ +L ++ + + +R+++ +EE +LR +E ++
Sbjct: 1651 QLRRQEREQQLRHD-RDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKF 1709
Query: 345 QHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAKKEKEQAKQLR 404
+Q R ++R EQ E E + + +++ ++ ++E++ +Q R
Sbjct: 1710 LQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQER 1769
Query: 405 RRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDH---QLQNMDKEDALICFEEH 461
R + + + ++ ++ + + Q+ QL+ ++ EE
Sbjct: 1770 DRKFREEEQLRQEREEQQLRS--QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQ 1827
Query: 462 IRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWME 512
++ EE+E+R R +ER +Q + E F T E + W E
Sbjct: 1828 LQL---EEQEQRLR---QERDRQYRAEEQFAT-----QEKSRREEQELWQE 1867
Score = 34.7 bits (78), Expect = 0.39
Identities = 51/267 (19%), Positives = 102/267 (38%), Gaps = 45/267 (16%)
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
L E E E++ E+ R RR E +R RQ W+E ER E+
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQ--RQE---------WQEREERRA-----EEE 191
Query: 654 TLESERIRLFREFL--QVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELP 711
L+S + EF + L + E L KGR+ ++ ++ R E EE+E
Sbjct: 192 QLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ----EEEEKEWR 247
Query: 712 PPSLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKK 771
R R+ EP + E + LRK ++ +
Sbjct: 248 K---RETVLRKEEEKLQEEEPQRQRELQEE------------------EEQLRKLERQEL 286
Query: 772 KTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGW 831
+ +++ + + + + +E + +EQ++++ + ++ E +++E+
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQE-- 344
Query: 832 DTSESELSEGELERRRRTLLQQLDDHQ 858
+ E +L + E RR L++ + +
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEE 371
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 68.2 bits (165), Expect = 3e-11
Identities = 78/370 (21%), Positives = 152/370 (41%), Gaps = 60/370 (16%)
Query: 50 PGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADD 109
P V P L P + + T+P +DT + PP + + DG + +D
Sbjct: 261 PSSVQPRHFLTLAP-IKIPLRTSPVSDTRTERGRVARPPALMLRAQKSRDG-----DKED 314
Query: 110 KQSVWEKPSVL-----------KSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 158
K E P +L + A + PW + + +++N S W +P
Sbjct: 315 K----EPPPMLGGGEDSTARGNRPVASTPVPGSPWCVVWTGDDRVFFFNPTMHLSVWEKP 370
Query: 159 KDLDDLEVL--VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGG 216
DL D L + ++ K++ + P T + +
Sbjct: 371 MDLKDRGDLNRIIEDPPHKRKLEAPATDNSDGSSSEDN---------------------- 408
Query: 217 SEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQA 276
ED DV + EG S + ++E++ ++ P + L R
Sbjct: 409 REDQDVKTK---------RNRTEGCGSPKPEEAKREDKGTRTPPPQILLPLEERVTH--- 456
Query: 277 FKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLR 336
F+++L ++ V + ++WE+ + +V DPRY L E+KQ F + R KEE +E + +
Sbjct: 457 FRDMLLERGVSAFSTWEKELHKIVFDPRYLLLNS-EERKQIFEQFVKTRIKEEYKEKKSK 515
Query: 337 AKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER-DRKEVYDDVLFFLAKK 395
AK+ + LE+ +++ T ++ + +G + + +V +R D++ ++ + L K+
Sbjct: 516 LLLAKEEFKKLLEE-SKVSPRTTFKEFAEKYGRDQRFRLVQKRKDQEHFFNQFILILKKR 574
Query: 396 EKEQAKQLRR 405
+KE +LR+
Sbjct: 575 DKENRLRLRK 584
Score = 38.5 bits (88), Expect = 0.027
Identities = 50/222 (22%), Positives = 76/222 (34%), Gaps = 52/222 (23%)
Query: 17 PMSQRPPAIPP---MPPG-----------ILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
PM PP PP M PG ++PP+L PP +PG +PG
Sbjct: 28 PMDAEPPPPPPWVWMVPGSAGLLRLSAGVVVPPVLLASAPPPAAPLLPG-----LPGWPA 82
Query: 63 PAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKS 122
P+ PV + S+A A P AL + + S+ PS
Sbjct: 83 PSEPVLPLLPLPSAPDSAAAAAAHPFPALHGQ---------WLFGGHSPSLGLPPSSTVE 133
Query: 123 KAELLLSQCP----------WKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 172
+ CP W + + K ++ N+ + +S W P +E+
Sbjct: 134 LVPVFPHLCPSALATPIGKSWIDKRIPNCKIFFNNSFALDSTWIHP-----------EES 182
Query: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
+ P+ L Q P P P+PT +L P+P
Sbjct: 183 RFFHGHEKPRLLANQVAVSLSRP---APASRPLPTVVLAPQP 221
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 64.3 bits (155), Expect = 5e-10
Identities = 51/151 (33%), Positives = 60/151 (39%), Gaps = 35/151 (23%)
Query: 2 PPPGIPPPFPPMGLP-------------PMSQRPPAIPPMPPGILPPMLPPMGAPPPL-T 47
PPPG PP P G+P P RPP PP PP LPP PP G PP L
Sbjct: 434 PPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPP 493
Query: 48 QIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHV--APDGRIYYY 105
P +PP PGM+ P + AP G PP L + V AP I
Sbjct: 494 PAPPGIPPPRPGMMRPPLVPPLGPAP---------PGLFPPAPLPNPGVLSAPPNLIQRP 544
Query: 106 NADDKQ----------SVWEKPSVLKSKAEL 126
ADD ++ KP + KAE+
Sbjct: 545 KADDTSAATIEKKATATISAKPQITNPKAEI 575
Score = 47.8 bits (112), Expect = 4e-05
Identities = 36/88 (40%), Positives = 40/88 (45%), Gaps = 14/88 (15%)
Query: 4 PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMP 63
P +P P PP+G PP PP PP PP LPP PP GAPP L PP MPG+
Sbjct: 405 PPMPGP-PPLGPPPA---PPLRPPGPPTGLPPG-PPPGAPPFLR------PPGMPGL--- 450
Query: 64 AVPVTAATAPGADTASSAVAGTGPPRAL 91
P+ PG GPP L
Sbjct: 451 RGPLPRLLPPGPPPGRPPGPPPGPPPGL 478
Score = 43.9 bits (102), Expect = 6e-04
Identities = 31/88 (35%), Positives = 38/88 (43%), Gaps = 15/88 (17%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPP-MPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
PPP PPP PP+ RPP P +PPG PP PP PP + + G +P ++P
Sbjct: 410 PPPLGPPPAPPL-------RPPGPPTGLPPGP-PPGAPPFLRPPGMPGLRGPLPRLLPPG 461
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPP 88
P P PG GPP
Sbjct: 462 PPPGRP------PGPPPGPPPGLPPGPP 483
Score = 36.2 bits (82), Expect = 0.13
Identities = 21/52 (40%), Positives = 25/52 (48%), Gaps = 16/52 (30%)
Query: 180 LPQTLQP-----QPPQPQPDPPP-VPPG----------PTPVPTGLLEPEPG 215
LP+ L P +PP P P PPP +PPG P P P G+ P PG
Sbjct: 454 LPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPG 505
Score = 35.0 bits (79), Expect = 0.30
Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPV--------PTGLLEPEPGGS 217
A QQQ PQ++ P Q P P P P GP P PTGL P G+
Sbjct: 386 ASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA 438
Score = 31.2 bits (69), Expect = 4.3
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 3/35 (8%)
Query: 181 PQTLQPQPPQPQPDP---PPVPPGPTPVPTGLLEP 212
P L P PP P P PP PPG P G++ P
Sbjct: 475 PPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRP 509
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 63.9 bits (154), Expect = 6e-10
Identities = 55/168 (32%), Positives = 72/168 (42%), Gaps = 30/168 (17%)
Query: 1 MPPPGIPPPF---------PPMGLPP---MSQRPPAIPPM------PPGILPPMLPPMGA 42
+PPPG+PPP PP G+PP + PP +PP PP +LPP A
Sbjct: 555 VPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTA 614
Query: 43 PPPLTQIPGM---VPPMMPGMLMPAVP------VTAATAPGADTASSAVAGTGPPRALWS 93
PPP+ +P + PP PG+ P VP +TAA P A ++ S+ P AL
Sbjct: 615 PPPVMPLPPLSSATPP--PGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLP 672
Query: 94 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTG 141
V+ QS V SKA L S P+ + SD G
Sbjct: 673 TPVSFGSAPPTTYHPPLQSAGPSEQV-NSKAPLSKSALPYSSFSSDQG 719
Score = 63.5 bits (153), Expect = 8e-10
Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 10/86 (11%)
Query: 6 IPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAV 65
+PPPF P SQ PP +P MPP +LPP LPP PP L P VPP PGM P +
Sbjct: 516 MPPPFVPY-----SQMPPPLPTMPPPVLPPSLPPPVMPPAL---PATVPP--PGMPPPVM 565
Query: 66 PVTAATAPGADTASSAVAGTGPPRAL 91
P + T+ +++ GPP L
Sbjct: 566 PPSLPTSVPPPGMPPSLSSAGPPPVL 591
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/58 (44%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPP---MPPGILPPM-LPPMGAPPPLTQIPGMVPP 55
PPPG P PPMG PP S P+ PP P PP+ +PP PPPL P ++ P
Sbjct: 1507 PPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKP 1564
Score = 45.4 bits (106), Expect = 2e-04
Identities = 78/330 (23%), Positives = 114/330 (34%), Gaps = 98/330 (29%)
Query: 1 MPPPGIP--------------PPFPPM-----------------------------GLPP 17
+PPP +P PP PPM GL P
Sbjct: 81 LPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVP 140
Query: 18 MS-QRPPAIPPMPPG--------ILPPMLPPMGAPPPLTQIPGMVPPM-MPGMLMPAVPV 67
M + PP PP+PPG +PP PP PP + P + P P P+
Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200
Query: 68 TAATAPGADTASSAVAGTGPPRA-LWSEHVAPDGRIYYYNAD-------------DKQSV 113
A T + ++SS+ + ++ L S +P ++ +K +V
Sbjct: 201 LAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV 260
Query: 114 WEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAA 173
++P +K + Q E T P Q ++ W R + L L+ K
Sbjct: 261 QQEPLESGAKNKSTEQQQAAPEPDPSTMTP-----QEQQQYWYR-QHLLSLQQRTKVHLP 314
Query: 174 G---------------KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSE 218
G K++ +P T Q P P + PP+PP VP L PE SE
Sbjct: 315 GHKKGPVVAKDTPEPVKEEVTVPATSQ-VPESPSSEEPPLPPPNEEVPPP-LPPEEPQSE 372
Query: 219 DCDVLEATQPLEQGFLQQLEEGPSSSGQHQ 248
D P E L+QL+ + QHQ
Sbjct: 373 D--------PEEDARLKQLQAAAAHWQQHQ 394
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/59 (44%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 11 PPMGLPPMSQRPPAIPPM--PPG-ILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVP 66
P M PP S RPP PPM PPG I+ P PP + P+T+ P +PP P +P P
Sbjct: 1503 PGMYPPPGSYRPP--PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPP 1559
Score = 39.3 bits (90), Expect = 0.016
Identities = 38/159 (23%), Positives = 62/159 (38%), Gaps = 11/159 (6%)
Query: 177 QQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQ 236
Q+ P L P + P+ PPVPPG P+ P P ++QP +L
Sbjct: 131 QRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQP----YLPP 186
Query: 237 LEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAM 296
+ PS S Q P P S S S++ + L +A PS S +
Sbjct: 187 AQPSPSQSPPSQ-----SYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSK 241
Query: 297 KMVVTDPRYSALP--KLSEKKQAFNAYKAQREKEEKEEA 333
++ P SA P K + +++ + + E+++ A
Sbjct: 242 SQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAA 280
Score = 38.9 bits (89), Expect = 0.021
Identities = 121/566 (21%), Positives = 197/566 (34%), Gaps = 116/566 (20%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGI----------------------------- 32
PP IPPP PP LPP PP I P +
Sbjct: 1542 PPVPIPPPPPPPPLPPP---PPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSE 1598
Query: 33 ---LP--PMLPPMGAPPPLTQI--PGMVPPMMPGMLM-PAVPVTAATAPGADTASSAVAG 84
+P P+LPP PP + I PG VP MP M P V T G D +++ V
Sbjct: 1599 TAAIPSAPVLPP---PPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVEQ 1655
Query: 85 TG------------PPRALW-SEHVAPDGRIYYYNADDKQSVWEKPS-VLKSKAELLLSQ 130
P R+ + +EH R Y D++ +++ S V+ + +
Sbjct: 1656 IPYGERITLRPDPLPERSTFETEHAGQRDR--YDRERDREPYFDRQSNVIADHRDFKRDR 1713
Query: 131 CPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQ 190
++ D G Y ++ + R RP+D K++ + ++ +P
Sbjct: 1714 ETHRDRDRDRGVIDY--DRDRFDRERRPRDDRAQSYRDKKDHSSSRRGGF-----DRPSY 1766
Query: 191 PQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQ 250
+ PV GP+ G E E PL P+ S HQP
Sbjct: 1767 DRKSDRPVYEGPSMF----------GGERRTYPEERMPL-----------PAPSLSHQPP 1805
Query: 251 QEEE-ESKPEPERSG--LSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSA 307
E KPE + L RE + ++R +P + A ++ D
Sbjct: 1806 PAPRVEKKPESKNVDDILKPPGRESRPERIVVIMR--GLPGSGKTHVA--KLIRDKEVEF 1861
Query: 308 LPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTF 367
+ + + EKEEK+ + + K + + E T+ ++ ++T
Sbjct: 1862 GGPAPRVLSLDDYFITEVEKEEKDPDSGKKVKKKVMEYEYEAEMEETYRTSMFKTFKKTL 1921
Query: 368 GELEVWAVVPE--RDRKEVYDDVLFFLAKKEK----------EQAKQLRRRNIQALKSIL 415
+ ++ + DR +D F+ A K K + +RNI K
Sbjct: 1922 DDGFFPFIILDAINDRVRHFDQ--FWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRK--- 1976
Query: 416 DGMSSVN-FQTTWSQAQQYLM--DNPSFAQDHQLQNMDKEDALICFEEHIRALEREEEEE 472
+ +N W A +++M D S QD ++ ++ ED EE + EEEE
Sbjct: 1977 --LKEINKMADHWETAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEEQKEEKKDAEEEE 2034
Query: 473 RERARLRERRQQRKNREAFQTFLDEL 498
E + + + + EA LD L
Sbjct: 2035 SELGYIPKSKWEMDTSEAKLDKLDGL 2060
Score = 35.8 bits (81), Expect = 0.17
Identities = 17/28 (60%), Positives = 20/28 (71%), Gaps = 5/28 (17%)
Query: 1 MPPP----GIPPPFP-PMGLPPMSQRPP 23
+PPP IPPP P PMG+PPMS+ PP
Sbjct: 1608 LPPPPVHSSIPPPGPVPMGMPPMSKPPP 1635
Score = 33.5 bits (75), Expect = 0.86
Identities = 37/173 (21%), Positives = 65/173 (37%), Gaps = 11/173 (6%)
Query: 168 VKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPV--PTGLLEPEPGGSEDCDVLEA 225
+ + +A + +P T P P P P PPP+PP P + T +E E + L
Sbjct: 1525 IVRPSAPPARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWD 1584
Query: 226 T---QPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLR 282
T Q L F + PS+ P P P G+ ++ Q +
Sbjct: 1585 TNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGH 1644
Query: 283 DKAVPSNASWEQAMKMVVTDPRYSALP-KLSEKKQAFNAYKAQREKEEKEEAR 334
+ + +N ++ + R + P L E+ + QR++ ++E R
Sbjct: 1645 GRDISTN-----KVEQIPYGERITLRPDPLPERSTFETEHAGQRDRYDRERDR 1692
Score = 32.7 bits (73), Expect = 1.5
Identities = 65/299 (21%), Positives = 97/299 (32%), Gaps = 58/299 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRP-------PAIP--------------------PMPPGILP 34
PPP +PPP PP+ LP S P PA P M +
Sbjct: 15 PPPPVPPP-PPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQ 73
Query: 35 PMLPPMGAPPPLTQIPGMVPPMMPG-----MLMPAVPVTAATAPGADTASSAVAGTGPPR 89
+L P PPP P PP+MPG P P+ P S +
Sbjct: 74 CVLQPHHLPPP----PLPPPPVMPGGGYGDWQPPPPPMPPPPGP---ALSYQKQQQYKHQ 126
Query: 90 ALWSEHVAPDGRIYYYNADDKQSVWEKPS--VLKSKAELLLSQCPWKEYKSDTGKPYYYN 147
L + P G + +S P + S++ + Q P Y + +PY
Sbjct: 127 MLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPP 186
Query: 148 NQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 207
Q S+ P L ++ Q Q P Q P G + +
Sbjct: 187 AQPSPSQ--SPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHS--KS 242
Query: 208 GLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLS 266
LL P P + G +++ P SG E++++ PEP+ S ++
Sbjct: 243 QLLAPPPPSA------------PPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMT 289
>gi|31652264 RNA binding motif protein 26 [Homo sapiens]
Length = 980
Score = 63.2 bits (152), Expect = 1e-09
Identities = 38/100 (38%), Positives = 50/100 (50%), Gaps = 10/100 (10%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP-GM 60
PPPG+PPP P + PP++ RPP +P PPG LPP LPP+ PPP +PP+ P GM
Sbjct: 342 PPPGLPPPPPILTPPPVNLRPP-VP--PPGPLPPSLPPVTGPPP------PLPPLQPSGM 392
Query: 61 LMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDG 100
P T++ T PP ++ DG
Sbjct: 393 DAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTADTYDTDG 432
Score = 45.1 bits (105), Expect = 3e-04
Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 8/91 (8%)
Query: 14 GLPPMSQRPPAIP-PMPPGILPPMLPPMGAPPPL-----TQIPGMVPPMMPGMLMPAVPV 67
G+ P +PP + P PPG+ PP PP+ PPP+ PG +PP +P + P P+
Sbjct: 327 GMLPFPAQPPVVEGPPPPGLPPP--PPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPL 384
Query: 68 TAATAPGADTASSAVAGTGPPRALWSEHVAP 98
G D ++ + P H P
Sbjct: 385 PPLQPSGMDAPPNSATSSVPTVVTTGIHHQP 415
Score = 37.0 bits (84), Expect = 0.078
Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGIL--PPMLPPMGAPPPLTQIPGMVPPMMP 58
+PPPG PP LPP++ PP +PP+ P + PP P +T PP P
Sbjct: 364 VPPPGPLPP----SLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAP 419
Query: 59 GMLMPA 64
L A
Sbjct: 420 PSLFTA 425
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 60.8 bits (146), Expect = 5e-09
Identities = 36/92 (39%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
Query: 3 PPGIPPPFPPM--GLPPMSQRPPAIPPMPPGILP-PMLPPMGAPPPLTQIPGMVPPMMPG 59
PPG+ P PP+ GLPP P ++PP PPG LP P +PP G P P +PP PG
Sbjct: 227 PPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPG 286
Query: 60 MLMPAV---PVTAATAPGADTASSAVAGTGPP 88
+ PA P + P A G PP
Sbjct: 287 VHPPAPVVHPPASGVHPPAPGVHPPAPGVHPP 318
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/95 (35%), Positives = 41/95 (43%), Gaps = 14/95 (14%)
Query: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPM----LPPMGAPPPLTQIPGMVPPM 56
+P P +PP P PP PP +PP PG+ PP P G PP PG+ PP
Sbjct: 259 LPLPPMPPTGPAPSGPP---GPPQLPPPAPGVHPPAPVVHPPASGVHPP---APGVHPP- 311
Query: 57 MPGMLMPAV---PVTAATAPGADTASSAVAGTGPP 88
PG+ PA P T+ P A G PP
Sbjct: 312 APGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPP 346
Score = 45.1 bits (105), Expect = 3e-04
Identities = 32/88 (36%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPA--IPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPG 59
P PG+ PP P + P PPA + P PG+ P P G PP PG+ PP PG
Sbjct: 311 PAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHP---PAPGVHPP---APGVHPP-APG 363
Query: 60 MLMPAVPVTAATAPGADTASSAVAGTGP 87
+ P APG A+ AV P
Sbjct: 364 VHPPPSAGVHPQAPGVHPAAPAVHPQAP 391
Score = 45.1 bits (105), Expect = 3e-04
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 6/57 (10%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPM-LPPMGAPPPLTQIPGMVPPMMP 58
PPG+ P P G+ P +PP + P PG+ PP +PPM PP ++ PG +PP P
Sbjct: 411 PPGVHPSAP--GVHP---QPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 43.9 bits (102), Expect = 6e-04
Identities = 25/71 (35%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 22 PPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGML-MPAVPVTA---ATAPGADT 77
PP++P PPG+ P P M PP +P +PP PG L +P +P T + PG
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQ 279
Query: 78 ASSAVAGTGPP 88
G PP
Sbjct: 280 LPPPAPGVHPP 290
Score = 40.4 bits (93), Expect = 0.007
Identities = 35/96 (36%), Positives = 41/96 (42%), Gaps = 19/96 (19%)
Query: 3 PPGIPPPFP------PMGLPPMSQRPPAIP---PMPPGILPPM----LPPMGAPPPLTQI 49
PP +PPP P P+ PP S P P P PG+ PP P G PP +
Sbjct: 277 PPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV 336
Query: 50 ----PGMVPPMMPGMLMPAVPVTAATAPGADTASSA 81
PG+ PP PG+ PA P APG SA
Sbjct: 337 HPPAPGVHPP-APGVHPPA-PGVHPPAPGVHPPPSA 370
Score = 40.0 bits (92), Expect = 0.009
Identities = 31/91 (34%), Positives = 40/91 (43%), Gaps = 18/91 (19%)
Query: 2 PPPGIPPPFPPMGLPPMS----QRP------PAIPPMPPGILPPMLPPMGAPPPLTQIPG 51
P PG+ PP P + PP + Q P PA+ P PG+ PP AP Q PG
Sbjct: 353 PAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPP------APGMHPQAPG 406
Query: 52 MVPPMMPGMLMPAVPVTAATAPGADTASSAV 82
V P PG + P+ P PG ++ V
Sbjct: 407 -VHPQPPG-VHPSAPGVHPQPPGVHPSNPGV 435
Score = 33.9 bits (76), Expect = 0.66
Identities = 18/40 (45%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 180 LPQTLQPQPPQPQPDPPPVPPGPTPV----PTGLLEPEPG 215
LP++L P PP P PP P GP P P L P PG
Sbjct: 247 LPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPG 286
Score = 32.3 bits (72), Expect = 1.9
Identities = 25/74 (33%), Positives = 32/74 (43%), Gaps = 11/74 (14%)
Query: 4 PGIPPPFPPMGLPPMSQRPPA--IPPMPPGILP------PMLPPMGAPPP--LTQIPGMV 53
PG+ P P + PPA + P PG+ P P P + PP PG+
Sbjct: 377 PGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVH 436
Query: 54 PPM-MPGMLMPAVP 66
PP MP ML P +P
Sbjct: 437 PPTPMPPMLRPPLP 450
Score = 32.0 bits (71), Expect = 2.5
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 6/73 (8%)
Query: 181 PQTLQPQPPQPQPDPPP----VPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQ 236
P +L PP + PPP +PP P P+P L P PGG + T P G
Sbjct: 220 PPSLPAGPPGVKRPPPPLMNGLPPRP-PLPESLPPPPPGGL-PLPPMPPTGPAPSGPPGP 277
Query: 237 LEEGPSSSGQHQP 249
+ P + G H P
Sbjct: 278 PQLPPPAPGVHPP 290
>gi|6005948 WW domain-containing binding protein 4 [Homo sapiens]
Length = 376
Score = 60.1 bits (144), Expect = 9e-09
Identities = 53/222 (23%), Positives = 84/222 (37%), Gaps = 31/222 (13%)
Query: 60 MLMPAVPVTAATAPGADTASSAVAGT-------GPPRALWSEHVAPDGRIYYYNADDKQS 112
+L P++ +T P T++ P + W E + +G YYY+ S
Sbjct: 89 ILEPSITPVTSTIPPTSTSNQQKEKKEKKKRKKDPSKGRWVEGITSEGYHYYYDLISGAS 148
Query: 113 VWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEA 172
WEKP + + + W E S+ G YYYN ++ ESRW +P DD
Sbjct: 149 QWEKPEGFQGDLKKTAVKTVWVEGLSEDGFTYYYNTETGESRWEKP---DDFIPHTSDLP 205
Query: 173 AGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQG 232
+ K + TL G E E GG + E+
Sbjct: 206 SSKVNENSLGTLDESKSSDSHSD----------SDGEQEAEEGG--------VSTETEKP 247
Query: 233 FLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAK 274
++ E+ +S G P+ ++E+S + G SN EK+K
Sbjct: 248 KIKFKEKNKNSDGGSDPETQKEKSIQKQNSLG---SNEEKSK 286
>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
Length = 478
Score = 59.3 bits (142), Expect = 1e-08
Identities = 37/101 (36%), Positives = 50/101 (49%), Gaps = 17/101 (16%)
Query: 1 MPP----PGIPPPFPPM--GLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVP 54
+PP PG+PP PP+ G+PP+ P +PP+ PG+ P M+P G PP IP ++P
Sbjct: 147 LPPVPGAPGMPPGIPPLMPGVPPLM---PGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMP 203
Query: 55 PMMPGM--------LMPAVPVTAATAPGADTASSAVAGTGP 87
M PGM + P A +APG A T P
Sbjct: 204 GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
Score = 56.2 bits (134), Expect = 1e-07
Identities = 74/286 (25%), Positives = 110/286 (38%), Gaps = 64/286 (22%)
Query: 1 MPP--PGIPPPFPPMG--LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQ-----IPG 51
MPP PG+PP PMG +PP PP +P MPPG +PP +P G PP+TQ PG
Sbjct: 174 MPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG-MPPPVPRPGI-PPMTQAQAVSAPG 231
Query: 52 MV-PPMMPGMLMPA--VPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNAD 108
++ P P +PA PVT P A + V + + SE ++ + + +
Sbjct: 232 ILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSN-SESLSASSKALFPSTA 290
Query: 109 DKQSVWEK------------------------PSVLKSKAEL--LLSQCPWKEYKSDTGK 142
Q+ + P+ +S A + K S T K
Sbjct: 291 QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK 350
Query: 143 PYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGP 202
P S S+ P +D+ + ++ K Q+ LP+ Q P +PP P G
Sbjct: 351 PATLTTTSATSKLIHPD--EDISLEERRAQLPKYQRNLPRPGQ----APIGNPPVGPIG- 403
Query: 203 TPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQ 248
G++ P+PG P +QG + G HQ
Sbjct: 404 -----GMMPPQPG-----------IPQQQGMRPPMPPHGQYGGHHQ 433
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/102 (37%), Positives = 49/102 (48%), Gaps = 21/102 (20%)
Query: 2 PPPGIPPPFPPMGLPPMSQRP---PAIPPMPPGI---LPPMLPPM-GAPPPLTQIPGM-- 52
P G PP GLPP+ P P IPP+ PG+ +P M P M G PP + + GM
Sbjct: 134 PQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMP 193
Query: 53 ----VPPMMPGM---LMPAVPVTAATAPGADTASSAVAGTGP 87
+PP+MPGM + P VP PG + A A + P
Sbjct: 194 PGPGIPPLMPGMPPGMPPPVP-----RPGIPPMTQAQAVSAP 230
Score = 39.7 bits (91), Expect = 0.012
Identities = 30/72 (41%), Positives = 35/72 (48%), Gaps = 20/72 (27%)
Query: 1 MPP-PGIP------PPFPP--------MGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP 45
MPP PGIP PP PP G+P P A+PP G PPM+PP PP
Sbjct: 406 MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP--GYLPGAMPPYGQG--PPMVPPYQGGPP 461
Query: 46 LTQIPGMVPPMM 57
+ GM PP+M
Sbjct: 462 RPPM-GMRPPVM 472
Score = 39.3 bits (90), Expect = 0.016
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 11/75 (14%)
Query: 19 SQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGM---VPPMMPGM--LMPAVPVTAATAP 73
S +P + P G +PPM P PP+ PGM +PP+MPG+ LMP +P P
Sbjct: 126 SFQPQPVQPQQ-GYIPPMAQP--GLPPVPGAPGMPPGIPPLMPGVPPLMPGMP---PVMP 179
Query: 74 GADTASSAVAGTGPP 88
G + G PP
Sbjct: 180 GMPPGMMPMGGMMPP 194
Score = 35.4 bits (80), Expect = 0.23
Identities = 25/71 (35%), Positives = 29/71 (40%), Gaps = 17/71 (23%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMP---------PGILPPMLPPMGAPPPLTQIPGM 52
P G+ PP P G+P P +PP PG LP +PP G PP M
Sbjct: 401 PIGGMMPPQP--GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP------M 452
Query: 53 VPPMMPGMLMP 63
VPP G P
Sbjct: 453 VPPYQGGPPRP 463
Score = 34.3 bits (77), Expect = 0.51
Identities = 24/71 (33%), Positives = 32/71 (45%), Gaps = 6/71 (8%)
Query: 149 QSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQ----PPQPQPDPPPVPPGPTP 204
+ K + K DD + ++A Q PQ +QPQ PP QP PPVP P
Sbjct: 98 EQKTQESQKKKQQDDSDEYDDDDSAASTSFQ-PQPVQPQQGYIPPMAQPGLPPVPGAP-G 155
Query: 205 VPTGLLEPEPG 215
+P G+ PG
Sbjct: 156 MPPGIPPLMPG 166
>gi|55749531 splicing factor 3B subunit 2 [Homo sapiens]
Length = 895
Score = 58.9 bits (141), Expect = 2e-08
Identities = 184/896 (20%), Positives = 327/896 (36%), Gaps = 251/896 (28%)
Query: 4 PGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMP 63
PGIP P PP+GLPP+ Q PP PP PPG +G P+ P + PP P
Sbjct: 88 PGIPMPPPPLGLPPL-QPPPPPPPPPPG--------LGLGFPMAHPPNLGPP-------P 131
Query: 64 AVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSK 123
+ V G P AL E E+ + + +
Sbjct: 132 PLRV------------------GEPVALSEE--------------------ERLKLAQQQ 153
Query: 124 AELLLSQCPWKEYKSDTG-KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQ 182
A LL+ Q + + D K + Q K + VL++QE +QQ++ +
Sbjct: 154 AALLMQQEERAKQQGDHSLKEHELLEQQKRAA-----------VLLEQE----RQQEIAK 198
Query: 183 --TLQPQPPQ------------PQPDPPPVPPGPTP--VPTGLLEPEPGG--------SE 218
T P+PPQ P+ P P GPTP +P G P P G +
Sbjct: 199 MGTPVPRPPQDMGQIGVRTPLGPRVAAPVGPVGPTPTVLPMGAPVPRPRGPPPPPGDENR 258
Query: 219 DCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFK 278
+ D + Q + L+ S + QQEEEE + + RS L S E +
Sbjct: 259 EMDDPSVGPKIPQALEKILQLKESRQEEMNSQQEEEEMETDA-RSSLGQSASETEEDT-- 315
Query: 279 ELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAK 338
+S K+ N + R+K++K + R+R
Sbjct: 316 --------------------------------VSVSKKEKNRKRRNRKKKKKPQ-RVRGV 342
Query: 339 EAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDDVLFFLAK---- 394
++ + +R +TR R ++ ++E+ V E E+Y+ F +
Sbjct: 343 SSESS-------GDREKDSTRSRGSDSPAADVEIEYVTEE---PEIYEPNFIFFKRIFEA 392
Query: 395 -KEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQDHQLQNMDKED 453
K + K+ + + + L + + + F ++H+ + D D
Sbjct: 393 FKLTDDVKKEKEKEPEKLDKLENSAAP---------------KKKGFEEEHKDSDDDSSD 437
Query: 454 ALICFEEHIRALEREEEEERERARLRERRQQRKNREAFQTFLDELHETGQLHSMSTWMEL 513
E+E++ E +L +++ +R NR + E QL + +E+
Sbjct: 438 D-------------EQEKKPEAPKLSKKKLRRMNRFT-------VAELKQLVARPDVVEM 477
Query: 514 YPAVSTDVRF-ANMLGQPGSTPLDLFKFYVEELKARFHDEKKIIKDILKVNTAFEDFAHV 572
+ + D + ++ S P+ + K ++ K+ I+ FE +
Sbjct: 478 HDVTAQDPKLLVHLKATRNSVPVPRHWCF----KRKYLQGKRGIE-----KPPFE----L 524
Query: 573 ISFDKRAAALDAGNIKLTFNSLLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALE 632
F KR E RE +EKEE + M+ + R +R + ++
Sbjct: 525 PDFIKRTGI----------------QEMREALQEKEEQKTMKSK---MREKVRPKMGKID 565
Query: 633 LGTAWEEVRERFVCDSAFEQITLESERIRLFREFLQVLEQTECQHLHTKGR-KHGRKGKK 691
+ ++++ + F ++T+ + +EF L++ + L + R G
Sbjct: 566 ID--YQKLHDAFFKWQTKPKLTIHGDLYYEGKEFETRLKEKKPGDLSDELRISLGMPVGP 623
Query: 692 HHHKRSHSPSGSESEEEELPPPSLRPPKRRRRNPSESGSEP---SSSLDSVESGGAALGG 748
+ HK +PPP L +R PS + +S + S G GG
Sbjct: 624 NAHK--------------VPPPWLIAMQRYGPPPSYPNLKIPGLNSPIPESCSFGYHAGG 669
Query: 749 RGSP-----SSHLLGADHGLRKAKKPKKKTKKRRHKSNSPESETDP-EEKAGKESDEKEQ 802
G P L G G A+ K ++ ++ P E +P +E++ +E +E+E
Sbjct: 670 WGKPPVDETGKPLYGDVFGTNAAEFQTKTEEEEIDRT--PWGELEPSDEESSEEEEEEES 727
Query: 803 EQDKDRE---LQQAELPNRSPGFGIKKEKTGWDTSESELSEGELERRRRTLLQQLD 855
++DK E + A+ +PG G G +T E +E R++ + + +D
Sbjct: 728 DEDKPDETGFITPADSGLITPG-GFSSVPAGMETPEL------IELRKKKIEEAMD 776
Score = 37.0 bits (84), Expect = 0.078
Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 18/92 (19%)
Query: 179 QLPQTLQPQPP------QPQPDPPPVPPG-----PTPVPTGLLEP------EPGGSEDCD 221
QLP P PP QP P PPP PPG P P L P EP + +
Sbjct: 86 QLPGIPMPPPPLGLPPLQPPPPPPPPPPGLGLGFPMAHPPNLGPPPPLRVGEPVALSEEE 145
Query: 222 VLEATQPLEQGFLQQLEEGPSSSGQHQPQQEE 253
L+ Q + L Q EE G H ++ E
Sbjct: 146 RLKLAQQ-QAALLMQQEERAKQQGDHSLKEHE 176
Score = 32.0 bits (71), Expect = 2.5
Identities = 14/29 (48%), Positives = 16/29 (55%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPP 30
PPP PPP P +GL PP + P PP
Sbjct: 104 PPPPPPPPPPGLGLGFPMAHPPNLGPPPP 132
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 66/288 (22%)
Query: 2 PPPGIPPPFPPM------GLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 45
PPPG P P PP G P+ P PP PP +L P PP APPP
Sbjct: 142 PPPG-PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 46 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 93
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 94 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 153
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 154 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 213
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 214 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 45.1 bits (105), Expect = 3e-04
Identities = 61/246 (24%), Positives = 87/246 (35%), Gaps = 53/246 (21%)
Query: 2 PPPGIPPPFPPMG---LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP 58
PPP + PP PP+ PP + P+IP PP +PP P PP +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPT-PPDFIPPAPPLAFLAPPPPPVPAPAPPA-- 238
Query: 59 GMLMPAVPVTAATA---PGADTA-SSAVAGTG---------PPRALWSEHVAPDGRIYYY 105
PA P T T PG T S VA G PPR+ P G
Sbjct: 239 ----PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS----PAEPKGSALGP 290
Query: 106 NADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGK---------------PYYYNNQS 150
N + + + + + + S P +E + K P ++ +
Sbjct: 291 NPEPHLT-FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPA 349
Query: 151 KE---SRWTRPKDLDDLEV-------LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPP 200
+ R P +L+ L + ++ ++ P P PP P PPP PP
Sbjct: 350 SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 201 GPTPVP 206
P P
Sbjct: 410 LPPAAP 415
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 5 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 61
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 62 MPAVPVTAATAP 73
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.17
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 54
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 55 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 87
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 25 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 81
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 82 VAGTGPPRALWSEHV 96
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 33.9 bits (76), Expect = 0.66
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 46/252 (18%)
Query: 20 QRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTAS 79
+R PP PP LPP PP+ PPP +P PP +P A P T ++
Sbjct: 385 ERAGTPPPAPP--LPPPAPPL--PPPAPPLPPAAPP-LPCAQKAAHPPAGFTKTPKSSSP 439
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ PP +P+ A W PS ++ L +
Sbjct: 440 ALKPKPNPP--------SPEN-----TASSAPVDWRDPSQMEKLRNELAA---------- 476
Query: 140 TGKPYYYNNQSKESRWT--RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPP 197
Y +E R+ RP + Q GK+ +LP+ + P D PP
Sbjct: 477 -----YLCGSRREDRFLSHRPG-----PTVAPQSKEGKKGPRLPEK-ETLLSLPAKDTPP 525
Query: 198 VPPGPTPVPTGLLEPEPG-----GSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQE 252
P + + L E E S D ++ P + +LE SS+ + + +
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 253 EEESKPEPERSG 264
P+P G
Sbjct: 586 IGSLPPKPRLEG 597
Score = 31.2 bits (69), Expect = 4.3
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 16/61 (26%)
Query: 184 LQPQPPQPQPDPP---PVPPGPTPVPTG----------LLEPEPGGS---EDCDVLEATQ 227
+ P PP P P PP PPG +P+P+ LLEP P S VLEA
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 228 P 228
P
Sbjct: 199 P 199
Score = 30.4 bits (67), Expect = 7.3
Identities = 57/258 (22%), Positives = 78/258 (30%), Gaps = 51/258 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------------- 45
P P +PP PP+ + PPA P P L P PP
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465
Query: 46 ----------------------LTQIPG--MVPPMMPGMLMPAVP--VTAATAPGADTAS 79
L+ PG + P G P +P T + P DT
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ +L AP + + + S ++++ E LS KE K
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 140 TG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-LQPQPPQPQPD 194
G KP + E+ D D L V + + LP T LQP+
Sbjct: 586 IGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 195 PPPVPPGPTPVPTGLLEP 212
PP P P P L P
Sbjct: 642 PPKATPEPAIPPKATLWP 659
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 66/288 (22%)
Query: 2 PPPGIPPPFPPM------GLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 45
PPPG P P PP G P+ P PP PP +L P PP APPP
Sbjct: 142 PPPG-PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 46 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 93
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 94 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 153
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 154 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 213
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 214 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 45.1 bits (105), Expect = 3e-04
Identities = 61/246 (24%), Positives = 87/246 (35%), Gaps = 53/246 (21%)
Query: 2 PPPGIPPPFPPMG---LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP 58
PPP + PP PP+ PP + P+IP PP +PP P PP +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPT-PPDFIPPAPPLAFLAPPPPPVPAPAPPA-- 238
Query: 59 GMLMPAVPVTAATA---PGADTA-SSAVAGTG---------PPRALWSEHVAPDGRIYYY 105
PA P T T PG T S VA G PPR+ P G
Sbjct: 239 ----PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS----PAEPKGSALGP 290
Query: 106 NADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGK---------------PYYYNNQS 150
N + + + + + + S P +E + K P ++ +
Sbjct: 291 NPEPHLT-FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPA 349
Query: 151 KE---SRWTRPKDLDDLEV-------LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPP 200
+ R P +L+ L + ++ ++ P P PP P PPP PP
Sbjct: 350 SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 201 GPTPVP 206
P P
Sbjct: 410 LPPAAP 415
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 5 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 61
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 62 MPAVPVTAATAP 73
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.17
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 54
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 55 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 87
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 25 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 81
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 82 VAGTGPPRALWSEHV 96
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 33.9 bits (76), Expect = 0.66
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 46/252 (18%)
Query: 20 QRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTAS 79
+R PP PP LPP PP+ PPP +P PP +P A P T ++
Sbjct: 385 ERAGTPPPAPP--LPPPAPPL--PPPAPPLPPAAPP-LPCAQKAAHPPAGFTKTPKSSSP 439
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ PP +P+ A W PS ++ L +
Sbjct: 440 ALKPKPNPP--------SPEN-----TASSAPVDWRDPSQMEKLRNELAA---------- 476
Query: 140 TGKPYYYNNQSKESRWT--RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPP 197
Y +E R+ RP + Q GK+ +LP+ + P D PP
Sbjct: 477 -----YLCGSRREDRFLSHRPG-----PTVAPQSKEGKKGPRLPEK-ETLLSLPAKDTPP 525
Query: 198 VPPGPTPVPTGLLEPEPG-----GSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQE 252
P + + L E E S D ++ P + +LE SS+ + + +
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 253 EEESKPEPERSG 264
P+P G
Sbjct: 586 IGSLPPKPRLEG 597
Score = 31.2 bits (69), Expect = 4.3
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 16/61 (26%)
Query: 184 LQPQPPQPQPDPP---PVPPGPTPVPTG----------LLEPEPGGS---EDCDVLEATQ 227
+ P PP P P PP PPG +P+P+ LLEP P S VLEA
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 228 P 228
P
Sbjct: 199 P 199
Score = 30.4 bits (67), Expect = 7.3
Identities = 57/258 (22%), Positives = 78/258 (30%), Gaps = 51/258 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------------- 45
P P +PP PP+ + PPA P P L P PP
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465
Query: 46 ----------------------LTQIPG--MVPPMMPGMLMPAVP--VTAATAPGADTAS 79
L+ PG + P G P +P T + P DT
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ +L AP + + + S ++++ E LS KE K
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 140 TG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-LQPQPPQPQPD 194
G KP + E+ D D L V + + LP T LQP+
Sbjct: 586 IGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 195 PPPVPPGPTPVPTGLLEP 212
PP P P P L P
Sbjct: 642 PPKATPEPAIPPKATLWP 659
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 58.2 bits (139), Expect = 3e-08
Identities = 78/288 (27%), Positives = 100/288 (34%), Gaps = 66/288 (22%)
Query: 2 PPPGIPPPFPPM------GLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------- 45
PPPG P P PP G P+ P PP PP +L P PP APPP
Sbjct: 142 PPPG-PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
Query: 46 -------LTQIPGMVPPMMP-GMLMPAVPVTAATAPGADTASSAVAGTG--PPRAL--WS 93
+ P +PP P L P P A AP A AS GT PP + W
Sbjct: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA-PASPHTVGTRLFPPGGVTKWK 259
Query: 94 EHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKES 153
VA +GR Q+ + S +S AE P +P+ +S +
Sbjct: 260 SDVALNGR---------QAEATRASPPRSPAE------PKGSALGPNPEPHLTFPRSFKV 304
Query: 154 RWTRPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPE 213
P + V QEA K++ + P P+PP P + P+
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKA---------PSRLPLPPSFHIRPASQVYPD 355
Query: 214 PGGSEDC-DVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
DC L+AT P GQ Q Q +E P P
Sbjct: 356 RAPEPDCPGELKATAPASPRL-----------GQSQSQADERAGTPPP 392
Score = 45.1 bits (105), Expect = 3e-04
Identities = 61/246 (24%), Positives = 87/246 (35%), Gaps = 53/246 (21%)
Query: 2 PPPGIPPPFPPMG---LPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP 58
PPP + PP PP+ PP + P+IP PP +PP P PP +P PP
Sbjct: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPT-PPDFIPPAPPLAFLAPPPPPVPAPAPPA-- 238
Query: 59 GMLMPAVPVTAATA---PGADTA-SSAVAGTG---------PPRALWSEHVAPDGRIYYY 105
PA P T T PG T S VA G PPR+ P G
Sbjct: 239 ----PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS----PAEPKGSALGP 290
Query: 106 NADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGK---------------PYYYNNQS 150
N + + + + + + S P +E + K P ++ +
Sbjct: 291 NPEPHLT-FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPA 349
Query: 151 KE---SRWTRPKDLDDLEV-------LVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPP 200
+ R P +L+ L + ++ ++ P P PP P PPP PP
Sbjct: 350 SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
Query: 201 GPTPVP 206
P P
Sbjct: 410 LPPAAP 415
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/72 (37%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 5 GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP--LTQIP-GMVPPMMPGML 61
G PPP PP+ PP PP PP+PP P A PP T+ P P + P
Sbjct: 388 GTPPPAPPLP-PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN 446
Query: 62 MPAVPVTAATAP 73
P+ TA++AP
Sbjct: 447 PPSPENTASSAP 458
Score = 35.8 bits (81), Expect = 0.17
Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 10/95 (10%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPM--------PPGILPPMLPPMGAPPPLTQIPGMVP 54
PP P L P + PAIPP P L P PP P T +
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG 678
Query: 55 PMMP--GMLMPAVPVTAATAPGADTASSAVAGTGP 87
P P PA+ TA T P + A +GP
Sbjct: 679 PTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 24/75 (32%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 25 IPPMPPGILPPMLPPMGAPP---PLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSA 81
IPP PPG P + PP PL P PP P +L P P + A P
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPV 193
Query: 82 VAGTGPPRALWSEHV 96
+ PP L S +
Sbjct: 194 LEALSPPHTLSSPSI 208
Score = 33.9 bits (76), Expect = 0.66
Identities = 56/252 (22%), Positives = 86/252 (34%), Gaps = 46/252 (18%)
Query: 20 QRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTAS 79
+R PP PP LPP PP+ PPP +P PP +P A P T ++
Sbjct: 385 ERAGTPPPAPP--LPPPAPPL--PPPAPPLPPAAPP-LPCAQKAAHPPAGFTKTPKSSSP 439
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ PP +P+ A W PS ++ L +
Sbjct: 440 ALKPKPNPP--------SPEN-----TASSAPVDWRDPSQMEKLRNELAA---------- 476
Query: 140 TGKPYYYNNQSKESRWT--RPKDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPP 197
Y +E R+ RP + Q GK+ +LP+ + P D PP
Sbjct: 477 -----YLCGSRREDRFLSHRPG-----PTVAPQSKEGKKGPRLPEK-ETLLSLPAKDTPP 525
Query: 198 VPPGPTPVPTGLLEPEPG-----GSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQE 252
P + + L E E S D ++ P + +LE SS+ + + +
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 253 EEESKPEPERSG 264
P+P G
Sbjct: 586 IGSLPPKPRLEG 597
Score = 31.2 bits (69), Expect = 4.3
Identities = 23/61 (37%), Positives = 27/61 (44%), Gaps = 16/61 (26%)
Query: 184 LQPQPPQPQPDPP---PVPPGPTPVPTG----------LLEPEPGGS---EDCDVLEATQ 227
+ P PP P P PP PPG +P+P+ LLEP P S VLEA
Sbjct: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
Query: 228 P 228
P
Sbjct: 199 P 199
Score = 30.4 bits (67), Expect = 7.3
Identities = 57/258 (22%), Positives = 78/258 (30%), Gaps = 51/258 (19%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPP---------------- 45
P P +PP PP+ + PPA P P L P PP
Sbjct: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465
Query: 46 ----------------------LTQIPG--MVPPMMPGMLMPAVP--VTAATAPGADTAS 79
L+ PG + P G P +P T + P DT
Sbjct: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
Query: 80 SAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSD 139
+ +L AP + + + S ++++ E LS KE K
Sbjct: 526 GVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPS 585
Query: 140 TG----KPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQQQQLPQT-LQPQPPQPQPD 194
G KP + E+ D D L V + + LP T LQP+
Sbjct: 586 IGSLPPKPRLEGGRICEN----GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAI 641
Query: 195 PPPVPPGPTPVPTGLLEP 212
PP P P P L P
Sbjct: 642 PPKATPEPAIPPKATLWP 659
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/300 (26%), Positives = 100/300 (33%), Gaps = 67/300 (22%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPP------MPPGILPPMLPPMGAPPPLTQIPGMVPP 55
PP GIPPP G+PP PP + P +PPG LPP G PPP+T + PP
Sbjct: 687 PPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----GPPPPITPPVSIPPP 741
Query: 56 MMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWE 115
P + ++P + DT G P + NA+ SV
Sbjct: 742 HTPPI---SIPNSTIAGINEDTTKDLSIGNPIPTVVSGAR---------GNAESGDSVKM 789
Query: 116 KPSVLKSKAELLLSQCPWKEYKS-------DTGKPYYYNNQSKESRWTRPKDLDDLEVLV 168
S + A L P + S G S RP ++
Sbjct: 790 YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP------GLIP 843
Query: 169 KQEAAGKQQQQLPQTLQPQPPQPQP------DPPPVPPG-PTPVPTGLL----------- 210
Q G L Q PP+P P PPP P G P P G+
Sbjct: 844 LQRPPGMPPPHL-QRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 902
Query: 211 ----------EPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
P PGG ED D + QP +Q Q + P Q Q QQ +P P
Sbjct: 903 PGGMPGLGGPGPGPGGPEDRDGRQ--QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 960
Score = 38.1 bits (87), Expect = 0.035
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 8/217 (3%)
Query: 170 QEAAGKQQQQLPQTLQPQPPQPQPDPP----PVPPGPTPVPTGLLEPEPGGSEDCDVLEA 225
Q+ A Q Q + Q QP+ Q DP P+PP GLL P V+
Sbjct: 313 QQPAYTQHQNMDQ-FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPP 371
Query: 226 TQPLEQGFLQ--QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 283
T P++Q F Q + P + HQ + E E+ + + +S + + +++ A + R
Sbjct: 372 TPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRR 431
Query: 284 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQ- 342
++ + S + + R + Q + +RE+ +K +++ + A
Sbjct: 432 RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVC 491
Query: 343 TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER 379
+ ++ Q ++ T+ + FG +E ++P R
Sbjct: 492 STTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPR 528
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 30 PGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAV--AGTGP 87
P LP +PP+ P P+T P VPP PG PV A P A T + G GP
Sbjct: 644 PKPLPVPVPPIPVPAPITVPPPQVPPHQPG-----PPVVGALQPPAFTPPLGIPPPGFGP 698
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 699 SPSGSESEEEELPPPSLRPPKRRRRNP---SESGSEPSSSLDSVESGGAALGGRGSPSSH 755
+P + ++++ PPPS +PP +++ +++ + +S D G + G R
Sbjct: 940 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRE 999
Query: 756 LLGADHGLRKAKKPKKKTKKRRHKSNSPESE--TDPEEKAGKESDEKEQEQD-KDRE 809
+G R + +R SP+ + D EE+ + S +++E+D +DRE
Sbjct: 1000 ----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRE 1052
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 1 MPPPGIPPPF---PPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 50
+PP G P F P PPM+Q P IPP PP P PLTQ P
Sbjct: 344 LPPNGQMPGFGLLPTPPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 394
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 185 QPQPPQPQPDPPPVPPGPTPVPTGLLEPE-PGGSEDCDVLEATQP 228
+P P P+P P PVPP P P P + P+ P V+ A QP
Sbjct: 638 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 682
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 182 QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
+T +P P P P PVP P PVP + P P
Sbjct: 633 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP 665
Score = 32.0 bits (71), Expect = 2.5
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 9 PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT---QIPGMVPPM--MPGMLMP 63
P P+ P PP P P + PP +PP PP+ Q P PP+ P P
Sbjct: 639 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 698
Query: 64 AVP 66
VP
Sbjct: 699 GVP 701
Score = 31.2 bits (69), Expect = 4.3
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 175 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 207
+Q QQ PQ PQ PQ Q P PP P PT
Sbjct: 930 QQPQQQPQPQAPQQPQQQQQQQP-PPSQQPPPT 961
Score = 30.4 bits (67), Expect = 7.3
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 463 RALEREEEEERERARLRERRQQRKNREAFQTFLDELH-ETGQLHSMSTWMELYPAVSTDV 521
R+ R+ R+R +ERR + K RE Q L ++ ET + S + W+ +T
Sbjct: 448 RSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQ 507
Query: 522 RFANMLGQPG 531
A++L + G
Sbjct: 508 DVASLLEEFG 517
Score = 30.0 bits (66), Expect = 9.6
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 12/74 (16%)
Query: 7 PPPFPPMGLPPMSQRPPA---------IPPMPPGILPPMLPPMGAPPPLTQIPG---MVP 54
PPP P G P + PA P GI + PP Q+PG +
Sbjct: 299 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 358
Query: 55 PMMPGMLMPAVPVT 68
P P M P +P T
Sbjct: 359 PPFPPMAQPVIPPT 372
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 58.2 bits (139), Expect = 3e-08
Identities = 79/300 (26%), Positives = 100/300 (33%), Gaps = 67/300 (22%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPP------MPPGILPPMLPPMGAPPPLTQIPGMVPP 55
PP GIPPP G+PP PP + P +PPG LPP G PPP+T + PP
Sbjct: 702 PPLGIPPPGFGPGVPPPPPPPPFLRPGFNPMHLPPGFLPP-----GPPPPITPPVSIPPP 756
Query: 56 MMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWE 115
P + ++P + DT G P + NA+ SV
Sbjct: 757 HTPPI---SIPNSTIAGINEDTTKDLSIGNPIPTVVSGAR---------GNAESGDSVKM 804
Query: 116 KPSVLKSKAELLLSQCPWKEYKS-------DTGKPYYYNNQSKESRWTRPKDLDDLEVLV 168
S + A L P + S G S RP ++
Sbjct: 805 YGSAVPPAAPTNLPTPPVTQPVSLLGTQGVAPGPVIGLQAPSTGLLGARP------GLIP 858
Query: 169 KQEAAGKQQQQLPQTLQPQPPQPQP------DPPPVPPG-PTPVPTGLL----------- 210
Q G L Q PP+P P PPP P G P P G+
Sbjct: 859 LQRPPGMPPPHL-QRFPLMPPRPMPPHMMHRGPPPGPGGFAMPPPHGMKGPFPPHGPFVR 917
Query: 211 ----------EPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
P PGG ED D + QP +Q Q + P Q Q QQ +P P
Sbjct: 918 PGGMPGLGGPGPGPGGPEDRDGRQ--QPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPPP 975
Score = 38.1 bits (87), Expect = 0.035
Identities = 45/217 (20%), Positives = 89/217 (41%), Gaps = 8/217 (3%)
Query: 170 QEAAGKQQQQLPQTLQPQPPQPQPDPP----PVPPGPTPVPTGLLEPEPGGSEDCDVLEA 225
Q+ A Q Q + Q QP+ Q DP P+PP GLL P V+
Sbjct: 328 QQPAYTQHQNMDQ-FQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPTPPFPPMAQPVIPP 386
Query: 226 TQPLEQGFLQ--QLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELLRD 283
T P++Q F Q + P + HQ + E E+ + + +S + + +++ A + R
Sbjct: 387 TPPVQQPFQASFQAQNEPLTQKPHQQEMEVEQPCIQEVKRHMSDNRKSRSRSASRSPKRR 446
Query: 284 KAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAKQ- 342
++ + S + + R + Q + +RE+ +K +++ + A
Sbjct: 447 RSRSGSRSRRSRHRRSRSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVC 506
Query: 343 TLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPER 379
+ ++ Q ++ T+ + FG +E ++P R
Sbjct: 507 STTLWVGQLDKRTTQQDVASLLEEFGPIESINMIPPR 543
Score = 35.4 bits (80), Expect = 0.23
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 7/60 (11%)
Query: 30 PGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGADTASSAV--AGTGP 87
P LP +PP+ P P+T P VPP PG PV A P A T + G GP
Sbjct: 659 PKPLPVPVPPIPVPAPITVPPPQVPPHQPG-----PPVVGALQPPAFTPPLGIPPPGFGP 713
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/117 (22%), Positives = 54/117 (46%), Gaps = 10/117 (8%)
Query: 699 SPSGSESEEEELPPPSLRPPKRRRRNP---SESGSEPSSSLDSVESGGAALGGRGSPSSH 755
+P + ++++ PPPS +PP +++ +++ + +S D G + G R
Sbjct: 955 APQQPQQQQQQQPPPSQQPPPTQQQPQQFRNDNRQQFNSGRDQERFGRRSFGNRVENDRE 1014
Query: 756 LLGADHGLRKAKKPKKKTKKRRHKSNSPESE--TDPEEKAGKESDEKEQEQD-KDRE 809
+G R + +R SP+ + D EE+ + S +++E+D +DRE
Sbjct: 1015 ----RYGNRNDDRDNSNRDRREWGRRSPDRDRHRDLEERNRRSSGHRDRERDSRDRE 1067
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/53 (41%), Positives = 24/53 (45%), Gaps = 5/53 (9%)
Query: 1 MPPPGIPPPF---PPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIP 50
+PP G P F P PPM+Q P IPP PP P PLTQ P
Sbjct: 359 LPPNGQMPGFGLLPTPPFPPMAQ--PVIPPTPPVQQPFQASFQAQNEPLTQKP 409
Score = 33.1 bits (74), Expect = 1.1
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 1/45 (2%)
Query: 185 QPQPPQPQPDPPPVPPGPTPVPTGLLEPE-PGGSEDCDVLEATQP 228
+P P P+P P PVPP P P P + P+ P V+ A QP
Sbjct: 653 EPVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQP 697
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 182 QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
+T +P P P P PVP P PVP + P P
Sbjct: 648 ETSHTEPVSPIPKPLPVPVPPIPVPAPITVPPP 680
Score = 32.0 bits (71), Expect = 2.5
Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 9 PFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLT---QIPGMVPPM--MPGMLMP 63
P P+ P PP P P + PP +PP PP+ Q P PP+ P P
Sbjct: 654 PVSPIPKPLPVPVPPIPVPAPITVPPPQVPPHQPGPPVVGALQPPAFTPPLGIPPPGFGP 713
Query: 64 AVP 66
VP
Sbjct: 714 GVP 716
Score = 31.2 bits (69), Expect = 4.3
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 1/33 (3%)
Query: 175 KQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPT 207
+Q QQ PQ PQ PQ Q P PP P PT
Sbjct: 945 QQPQQQPQPQAPQQPQQQQQQQP-PPSQQPPPT 976
Score = 30.4 bits (67), Expect = 7.3
Identities = 20/70 (28%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 463 RALEREEEEERERARLRERRQQRKNREAFQTFLDELH-ETGQLHSMSTWMELYPAVSTDV 521
R+ R+ R+R +ERR + K RE Q L ++ ET + S + W+ +T
Sbjct: 463 RSRSRDRRRHSPRSRSQERRDREKERERRQKGLPQVKPETASVCSTTLWVGQLDKRTTQQ 522
Query: 522 RFANMLGQPG 531
A++L + G
Sbjct: 523 DVASLLEEFG 532
Score = 30.0 bits (66), Expect = 9.6
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 12/74 (16%)
Query: 7 PPPFPPMGLPPMSQRPPA---------IPPMPPGILPPMLPPMGAPPPLTQIPG---MVP 54
PPP P G P + PA P GI + PP Q+PG +
Sbjct: 314 PPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLLPT 373
Query: 55 PMMPGMLMPAVPVT 68
P P M P +P T
Sbjct: 374 PPFPPMAQPVIPPT 387
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 55/361 (15%)
Query: 165 EVLVKQEAAG---KQQQQLP------QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP- 214
+VL +Q+ A +QQQQL QTL+ + P P + E +P
Sbjct: 632 QVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT 691
Query: 215 --------GGSEDCDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERS 263
GGS L+ T P LEQ LQQLE+ ++ + + ++ E +K E E
Sbjct: 692 ASQPTVWEGGSVWDLPLDTTTPGPALEQ--LQQLEKAKAAKLEQERREAEMRAKREEEER 749
Query: 264 GLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKA 323
+E+ ++ +E+LR + E+ + + + AL + E++ A +
Sbjct: 750 ----KRQEELRRQQEEILRRQQEEERKRREE--EELARRKQEEALRRQREQEIALRRQRE 803
Query: 324 QREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKE 383
+ E++++EEA R +E ++ E+ ER R+ E+ E WA E ++
Sbjct: 804 EEERQQQEEALRRLEERRR------EEEERRKQEELLRKQEE---EAAKWAREEEEAQRR 854
Query: 384 VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD 443
+ ++ L + +E+A +LR + + L+ Q Q+ L Q
Sbjct: 855 LEENRL-----RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 909
Query: 444 HQLQNM---------DKEDALICFEE---HIRALEREEEEERERARLRERRQQRKNREAF 491
QL M + + C + + +++ EEE + R +RRQQR+ +A
Sbjct: 910 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 969
Query: 492 Q 492
Q
Sbjct: 970 Q 970
Score = 38.9 bits (89), Expect = 0.021
Identities = 63/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 595 LEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQIT 654
LEKA+A + E+E+ EA +RE R RQ EL EE+ R
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERK--RQE----ELRRQQEEILRR----------Q 766
Query: 655 LESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPS 714
E ER R E L +Q E + R+ + E EE + +
Sbjct: 767 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR-------------EEEERQQQEEA 813
Query: 715 LRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK-----KP 769
LR + RRR E + L + AA R + ++ LR + +
Sbjct: 814 LRRLEERRREEEERRKQ--EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 871
Query: 770 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKT 829
+++ +KR+ + E + + +E+ + Q+Q + ++L Q +LP+ S +G + T
Sbjct: 872 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQSNTT 930
Query: 830 GWDTSESELSEGELERRRRTLLQQLDDHQ 858
S++ LS E+++ +QL + Q
Sbjct: 931 ACQ-SQATLSLAEIQKLEEERERQLREEQ 958
Score = 37.4 bits (85), Expect = 0.060
Identities = 52/265 (19%), Positives = 104/265 (39%), Gaps = 8/265 (3%)
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
+L + + ER+R +EE R++E A R Q + AL EE +++ E+
Sbjct: 762 ILRRQQEEERKRREEEELARRKQEEALRRQREQEI-ALRRQREEEERQQQEEALRRLEER 820
Query: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
E E R E L+ E+ E + + R+ +++ + + EEEE
Sbjct: 821 RREEEERRKQEELLRKQEE-EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 879
Query: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
L +++ + + + L PSS G +++ ++
Sbjct: 880 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG-----QQSNTTACQS 934
Query: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
+ + + E + E + +E +++E K + QQ + + G+G + +G
Sbjct: 935 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
Query: 834 SESELSEGELERRRRTLLQQLDDHQ 858
S E+ + E R+ + QQ HQ
Sbjct: 995 SLLEIQQEE-ARQMQKQQQQQQQHQ 1018
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 164 LEVLVKQEA-AGKQQQQLPQTLQPQPPQPQPDPP 196
LE KQ+A +QQQQLPQ Q QPPQ P P
Sbjct: 1186 LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQP 1219
Score = 33.9 bits (76), Expect = 0.66
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL--- 280
EA + LE+ L+ EE ++ ++E + + E +R R++ ++A + L
Sbjct: 850 EAQRRLEENRLRMEEE---AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 906
Query: 281 -----LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARL 335
L +PS+++W Q T + A L+E ++ + +RE++ +EE R
Sbjct: 907 QQQQQLAQMKLPSSSTWGQQSN--TTACQSQATLSLAEIQKL----EEERERQLREEQRR 960
Query: 336 RAKEAKQTLQHFLEQHERMTS 356
+ +E + LQ +Q ++ S
Sbjct: 961 QQRELMKALQQQQQQQQQKLS 981
Score = 32.7 bits (73), Expect = 1.5
Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 665 EFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRN 724
E LQ LE+ + L + R+ + K+ +R ++EE+ ++RR
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE-LRRQQEEILRRQQEEERKRREE 776
Query: 725 PSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPE 784
+ + +L AL R + LR+ ++ +++ ++RR + E
Sbjct: 777 EELARRKQEEALRRQREQEIAL-RRQREEEERQQQEEALRRLEERRREEEERRKQE---E 832
Query: 785 SETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELE 844
EE+A K + E+E+ Q R L++ L ++ E E E ELE
Sbjct: 833 LLRKQEEEAAKWAREEEEAQ---RRLEENRLRMEEEAARLRHE-------EEERKRKELE 882
Query: 845 -RRRRTLLQQLDDHQ 858
+R++ L++Q Q
Sbjct: 883 VQRQKELMRQRQQQQ 897
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 55/361 (15%)
Query: 165 EVLVKQEAAG---KQQQQLP------QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP- 214
+VL +Q+ A +QQQQL QTL+ + P P + E +P
Sbjct: 659 QVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT 718
Query: 215 --------GGSEDCDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERS 263
GGS L+ T P LEQ LQQLE+ ++ + + ++ E +K E E
Sbjct: 719 ASQPTVWEGGSVWDLPLDTTTPGPALEQ--LQQLEKAKAAKLEQERREAEMRAKREEEER 776
Query: 264 GLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKA 323
+E+ ++ +E+LR + E+ + + + AL + E++ A +
Sbjct: 777 ----KRQEELRRQQEEILRRQQEEERKRREE--EELARRKQEEALRRQREQEIALRRQRE 830
Query: 324 QREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKE 383
+ E++++EEA R +E ++ E+ ER R+ E+ E WA E ++
Sbjct: 831 EEERQQQEEALRRLEERRR------EEEERRKQEELLRKQEE---EAAKWAREEEEAQRR 881
Query: 384 VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD 443
+ ++ L + +E+A +LR + + L+ Q Q+ L Q
Sbjct: 882 LEENRL-----RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 936
Query: 444 HQLQNM---------DKEDALICFEE---HIRALEREEEEERERARLRERRQQRKNREAF 491
QL M + + C + + +++ EEE + R +RRQQR+ +A
Sbjct: 937 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 996
Query: 492 Q 492
Q
Sbjct: 997 Q 997
Score = 38.9 bits (89), Expect = 0.021
Identities = 63/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 595 LEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQIT 654
LEKA+A + E+E+ EA +RE R RQ EL EE+ R
Sbjct: 750 LEKAKAAKLEQERREAEMRAKREEEERK--RQE----ELRRQQEEILRR----------Q 793
Query: 655 LESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPS 714
E ER R E L +Q E + R+ + E EE + +
Sbjct: 794 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR-------------EEEERQQQEEA 840
Query: 715 LRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK-----KP 769
LR + RRR E + L + AA R + ++ LR + +
Sbjct: 841 LRRLEERRREEEERRKQ--EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 898
Query: 770 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKT 829
+++ +KR+ + E + + +E+ + Q+Q + ++L Q +LP+ S +G + T
Sbjct: 899 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQSNTT 957
Query: 830 GWDTSESELSEGELERRRRTLLQQLDDHQ 858
S++ LS E+++ +QL + Q
Sbjct: 958 ACQ-SQATLSLAEIQKLEEERERQLREEQ 985
Score = 37.4 bits (85), Expect = 0.060
Identities = 52/265 (19%), Positives = 104/265 (39%), Gaps = 8/265 (3%)
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
+L + + ER+R +EE R++E A R Q + AL EE +++ E+
Sbjct: 789 ILRRQQEEERKRREEEELARRKQEEALRRQREQEI-ALRRQREEEERQQQEEALRRLEER 847
Query: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
E E R E L+ E+ E + + R+ +++ + + EEEE
Sbjct: 848 RREEEERRKQEELLRKQEE-EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 906
Query: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
L +++ + + + L PSS G +++ ++
Sbjct: 907 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG-----QQSNTTACQS 961
Query: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
+ + + E + E + +E +++E K + QQ + + G+G + +G
Sbjct: 962 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
Query: 834 SESELSEGELERRRRTLLQQLDDHQ 858
S E+ + E R+ + QQ HQ
Sbjct: 1022 SLLEIQQEE-ARQMQKQQQQQQQHQ 1045
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 164 LEVLVKQEA-AGKQQQQLPQTLQPQPPQPQPDPP 196
LE KQ+A +QQQQLPQ Q QPPQ P P
Sbjct: 1213 LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQP 1246
Score = 33.9 bits (76), Expect = 0.66
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL--- 280
EA + LE+ L+ EE ++ ++E + + E +R R++ ++A + L
Sbjct: 877 EAQRRLEENRLRMEEE---AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 933
Query: 281 -----LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARL 335
L +PS+++W Q T + A L+E ++ + +RE++ +EE R
Sbjct: 934 QQQQQLAQMKLPSSSTWGQQSN--TTACQSQATLSLAEIQKL----EEERERQLREEQRR 987
Query: 336 RAKEAKQTLQHFLEQHERMTS 356
+ +E + LQ +Q ++ S
Sbjct: 988 QQRELMKALQQQQQQQQQKLS 1008
Score = 32.7 bits (73), Expect = 1.5
Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 665 EFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRN 724
E LQ LE+ + L + R+ + K+ +R ++EE+ ++RR
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE-LRRQQEEILRRQQEEERKRREE 803
Query: 725 PSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPE 784
+ + +L AL R + LR+ ++ +++ ++RR + E
Sbjct: 804 EELARRKQEEALRRQREQEIAL-RRQREEEERQQQEEALRRLEERRREEEERRKQE---E 859
Query: 785 SETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELE 844
EE+A K + E+E+ Q R L++ L ++ E E E ELE
Sbjct: 860 LLRKQEEEAAKWAREEEEAQ---RRLEENRLRMEEEAARLRHE-------EEERKRKELE 909
Query: 845 -RRRRTLLQQLDDHQ 858
+R++ L++Q Q
Sbjct: 910 VQRQKELMRQRQQQQ 924
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 55/361 (15%)
Query: 165 EVLVKQEAAG---KQQQQLP------QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP- 214
+VL +Q+ A +QQQQL QTL+ + P P + E +P
Sbjct: 638 QVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT 697
Query: 215 --------GGSEDCDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERS 263
GGS L+ T P LEQ LQQLE+ ++ + + ++ E +K E E
Sbjct: 698 ASQPTVWEGGSVWDLPLDTTTPGPALEQ--LQQLEKAKAAKLEQERREAEMRAKREEEER 755
Query: 264 GLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKA 323
+E+ ++ +E+LR + E+ + + + AL + E++ A +
Sbjct: 756 ----KRQEELRRQQEEILRRQQEEERKRREE--EELARRKQEEALRRQREQEIALRRQRE 809
Query: 324 QREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKE 383
+ E++++EEA R +E ++ E+ ER R+ E+ E WA E ++
Sbjct: 810 EEERQQQEEALRRLEERRR------EEEERRKQEELLRKQEE---EAAKWAREEEEAQRR 860
Query: 384 VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD 443
+ ++ L + +E+A +LR + + L+ Q Q+ L Q
Sbjct: 861 LEENRL-----RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 915
Query: 444 HQLQNM---------DKEDALICFEE---HIRALEREEEEERERARLRERRQQRKNREAF 491
QL M + + C + + +++ EEE + R +RRQQR+ +A
Sbjct: 916 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Query: 492 Q 492
Q
Sbjct: 976 Q 976
Score = 38.9 bits (89), Expect = 0.021
Identities = 63/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 595 LEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQIT 654
LEKA+A + E+E+ EA +RE R RQ EL EE+ R
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERK--RQE----ELRRQQEEILRR----------Q 772
Query: 655 LESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPS 714
E ER R E L +Q E + R+ + E EE + +
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR-------------EEEERQQQEEA 819
Query: 715 LRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK-----KP 769
LR + RRR E + L + AA R + ++ LR + +
Sbjct: 820 LRRLEERRREEEERRKQ--EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877
Query: 770 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKT 829
+++ +KR+ + E + + +E+ + Q+Q + ++L Q +LP+ S +G + T
Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQSNTT 936
Query: 830 GWDTSESELSEGELERRRRTLLQQLDDHQ 858
S++ LS E+++ +QL + Q
Sbjct: 937 ACQ-SQATLSLAEIQKLEEERERQLREEQ 964
Score = 37.4 bits (85), Expect = 0.060
Identities = 52/265 (19%), Positives = 104/265 (39%), Gaps = 8/265 (3%)
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
+L + + ER+R +EE R++E A R Q + AL EE +++ E+
Sbjct: 768 ILRRQQEEERKRREEEELARRKQEEALRRQREQEI-ALRRQREEEERQQQEEALRRLEER 826
Query: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
E E R E L+ E+ E + + R+ +++ + + EEEE
Sbjct: 827 RREEEERRKQEELLRKQEE-EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
L +++ + + + L PSS G +++ ++
Sbjct: 886 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG-----QQSNTTACQS 940
Query: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
+ + + E + E + +E +++E K + QQ + + G+G + +G
Sbjct: 941 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
Query: 834 SESELSEGELERRRRTLLQQLDDHQ 858
S E+ + E R+ + QQ HQ
Sbjct: 1001 SLLEIQQEE-ARQMQKQQQQQQQHQ 1024
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 164 LEVLVKQEA-AGKQQQQLPQTLQPQPPQPQPDPP 196
LE KQ+A +QQQQLPQ Q QPPQ P P
Sbjct: 1192 LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQP 1225
Score = 33.9 bits (76), Expect = 0.66
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL--- 280
EA + LE+ L+ EE ++ ++E + + E +R R++ ++A + L
Sbjct: 856 EAQRRLEENRLRMEEE---AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 281 -----LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARL 335
L +PS+++W Q T + A L+E ++ + +RE++ +EE R
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSN--TTACQSQATLSLAEIQKL----EEERERQLREEQRR 966
Query: 336 RAKEAKQTLQHFLEQHERMTS 356
+ +E + LQ +Q ++ S
Sbjct: 967 QQRELMKALQQQQQQQQQKLS 987
Score = 32.7 bits (73), Expect = 1.5
Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 665 EFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRN 724
E LQ LE+ + L + R+ + K+ +R ++EE+ ++RR
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE-LRRQQEEILRRQQEEERKRREE 782
Query: 725 PSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPE 784
+ + +L AL R + LR+ ++ +++ ++RR + E
Sbjct: 783 EELARRKQEEALRRQREQEIAL-RRQREEEERQQQEEALRRLEERRREEEERRKQE---E 838
Query: 785 SETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELE 844
EE+A K + E+E+ Q R L++ L ++ E E E ELE
Sbjct: 839 LLRKQEEEAAKWAREEEEAQ---RRLEENRLRMEEEAARLRHE-------EEERKRKELE 888
Query: 845 -RRRRTLLQQLDDHQ 858
+R++ L++Q Q
Sbjct: 889 VQRQKELMRQRQQQQ 903
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 57.8 bits (138), Expect = 4e-08
Identities = 83/361 (22%), Positives = 150/361 (41%), Gaps = 55/361 (15%)
Query: 165 EVLVKQEAAG---KQQQQLP------QTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEP- 214
+VL +Q+ A +QQQQL QTL+ + P P + E +P
Sbjct: 638 QVLAQQQKAALSSQQQQQLALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT 697
Query: 215 --------GGSEDCDVLEATQP---LEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERS 263
GGS L+ T P LEQ LQQLE+ ++ + + ++ E +K E E
Sbjct: 698 ASQPTVWEGGSVWDLPLDTTTPGPALEQ--LQQLEKAKAAKLEQERREAEMRAKREEEER 755
Query: 264 GLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKA 323
+E+ ++ +E+LR + E+ + + + AL + E++ A +
Sbjct: 756 ----KRQEELRRQQEEILRRQQEEERKRREE--EELARRKQEEALRRQREQEIALRRQRE 809
Query: 324 QREKEEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKE 383
+ E++++EEA R +E ++ E+ ER R+ E+ E WA E ++
Sbjct: 810 EEERQQQEEALRRLEERRR------EEEERRKQEELLRKQEE---EAAKWAREEEEAQRR 860
Query: 384 VYDDVLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD 443
+ ++ L + +E+A +LR + + L+ Q Q+ L Q
Sbjct: 861 LEENRL-----RMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQ 915
Query: 444 HQLQNM---------DKEDALICFEE---HIRALEREEEEERERARLRERRQQRKNREAF 491
QL M + + C + + +++ EEE + R +RRQQR+ +A
Sbjct: 916 QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKAL 975
Query: 492 Q 492
Q
Sbjct: 976 Q 976
Score = 38.9 bits (89), Expect = 0.021
Identities = 63/269 (23%), Positives = 109/269 (40%), Gaps = 38/269 (14%)
Query: 595 LEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQIT 654
LEKA+A + E+E+ EA +RE R RQ EL EE+ R
Sbjct: 729 LEKAKAAKLEQERREAEMRAKREEEERK--RQE----ELRRQQEEILRR----------Q 772
Query: 655 LESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPS 714
E ER R E L +Q E + R+ + E EE + +
Sbjct: 773 QEEERKRREEEELARRKQEEALRRQREQEIALRRQR-------------EEEERQQQEEA 819
Query: 715 LRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAK-----KP 769
LR + RRR E + L + AA R + ++ LR + +
Sbjct: 820 LRRLEERRREEEERRKQ--EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877
Query: 770 KKKTKKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKT 829
+++ +KR+ + E + + +E+ + Q+Q + ++L Q +LP+ S +G + T
Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSST-WGQQSNTT 936
Query: 830 GWDTSESELSEGELERRRRTLLQQLDDHQ 858
S++ LS E+++ +QL + Q
Sbjct: 937 ACQ-SQATLSLAEIQKLEEERERQLREEQ 964
Score = 37.4 bits (85), Expect = 0.060
Identities = 52/265 (19%), Positives = 104/265 (39%), Gaps = 8/265 (3%)
Query: 594 LLEKAEAREREREKEEARRMRRREAAFRSMLRQAVPALELGTAWEEVRERFVCDSAFEQI 653
+L + + ER+R +EE R++E A R Q + AL EE +++ E+
Sbjct: 768 ILRRQQEEERKRREEEELARRKQEEALRRQREQEI-ALRRQREEEERQQQEEALRRLEER 826
Query: 654 TLESERIRLFREFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPP 713
E E R E L+ E+ E + + R+ +++ + + EEEE
Sbjct: 827 RREEEERRKQEELLRKQEE-EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRK 885
Query: 714 SLRPPKRRRRNPSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKT 773
L +++ + + + L PSS G +++ ++
Sbjct: 886 ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWG-----QQSNTTACQS 940
Query: 774 KKRRHKSNSPESETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDT 833
+ + + E + E + +E +++E K + QQ + + G+G + +G
Sbjct: 941 QATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
Query: 834 SESELSEGELERRRRTLLQQLDDHQ 858
S E+ + E R+ + QQ HQ
Sbjct: 1001 SLLEIQQEE-ARQMQKQQQQQQQHQ 1024
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/34 (55%), Positives = 21/34 (61%), Gaps = 1/34 (2%)
Query: 164 LEVLVKQEA-AGKQQQQLPQTLQPQPPQPQPDPP 196
LE KQ+A +QQQQLPQ Q QPPQ P P
Sbjct: 1192 LERRAKQKANQQRQQQQLPQQQQQQPPQQPPQQP 1225
Score = 33.9 bits (76), Expect = 0.66
Identities = 32/141 (22%), Positives = 66/141 (46%), Gaps = 17/141 (12%)
Query: 224 EATQPLEQGFLQQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKEL--- 280
EA + LE+ L+ EE ++ ++E + + E +R R++ ++A + L
Sbjct: 856 EAQRRLEENRLRMEEE---AARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQ 912
Query: 281 -----LRDKAVPSNASWEQAMKMVVTDPRYSALPKLSEKKQAFNAYKAQREKEEKEEARL 335
L +PS+++W Q T + A L+E ++ + +RE++ +EE R
Sbjct: 913 QQQQQLAQMKLPSSSTWGQQSN--TTACQSQATLSLAEIQKL----EEERERQLREEQRR 966
Query: 336 RAKEAKQTLQHFLEQHERMTS 356
+ +E + LQ +Q ++ S
Sbjct: 967 QQRELMKALQQQQQQQQQKLS 987
Score = 32.7 bits (73), Expect = 1.5
Identities = 42/195 (21%), Positives = 80/195 (41%), Gaps = 16/195 (8%)
Query: 665 EFLQVLEQTECQHLHTKGRKHGRKGKKHHHKRSHSPSGSESEEEELPPPSLRPPKRRRRN 724
E LQ LE+ + L + R+ + K+ +R ++EE+ ++RR
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEE-LRRQQEEILRRQQEEERKRREE 782
Query: 725 PSESGSEPSSSLDSVESGGAALGGRGSPSSHLLGADHGLRKAKKPKKKTKKRRHKSNSPE 784
+ + +L AL R + LR+ ++ +++ ++RR + E
Sbjct: 783 EELARRKQEEALRRQREQEIAL-RRQREEEERQQQEEALRRLEERRREEEERRKQE---E 838
Query: 785 SETDPEEKAGKESDEKEQEQDKDRELQQAELPNRSPGFGIKKEKTGWDTSESELSEGELE 844
EE+A K + E+E+ Q R L++ L ++ E E E ELE
Sbjct: 839 LLRKQEEEAAKWAREEEEAQ---RRLEENRLRMEEEAARLRHE-------EEERKRKELE 888
Query: 845 -RRRRTLLQQLDDHQ 858
+R++ L++Q Q
Sbjct: 889 VQRQKELMRQRQQQQ 903
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 57.8 bits (138), Expect = 4e-08
Identities = 34/75 (45%), Positives = 37/75 (49%), Gaps = 9/75 (12%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPP---MGAPPPLTQIPGMVPPMMP 58
PPP + P P G PP+ PP PP PG PP PP G PPP PG PP P
Sbjct: 273 PPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPP----PGPFPPRPP 328
Query: 59 GMLMPAVPVTAATAP 73
G L P P+T A P
Sbjct: 329 GPLGP--PLTLAPPP 341
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/91 (39%), Positives = 39/91 (42%), Gaps = 9/91 (9%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
PPG PPP P G PP P PP PPG PP PP PPLT P PP +PG
Sbjct: 293 PPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAP---PPHLPGPPP 348
Query: 63 PAVPVT-----AATAPGADTASSAVAGTGPP 88
A P A P ++ GPP
Sbjct: 349 GAPPPAPHVNPAFFPPPTNSGMPTSDSRGPP 379
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/89 (41%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMG--APPPLTQIPGMVPPMMPGM 60
P G PPPFP PP RPP PP PPG PP PP G PPPL P P +
Sbjct: 223 PGGPPPPFPAGQTPP---RPPLGPPGPPG--PPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277
Query: 61 LMPAVPV-TAATAPGADTASSAVAGTGPP 88
L P P P V G GPP
Sbjct: 278 LFPGQPFGQPPLGPLPPGPPPPVPGYGPP 306
Score = 51.2 bits (121), Expect = 4e-06
Identities = 30/69 (43%), Positives = 32/69 (46%), Gaps = 15/69 (21%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPP----AIPPMPPGILPPML----------PPMGAPPPLT 47
PPP +P PP G PP Q PP PP PPG L P L PP GAPPP
Sbjct: 296 PPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAP 355
Query: 48 QI-PGMVPP 55
+ P PP
Sbjct: 356 HVNPAFFPP 364
Score = 44.3 bits (103), Expect = 5e-04
Identities = 34/93 (36%), Positives = 39/93 (41%), Gaps = 23/93 (24%)
Query: 2 PPPGIP----PPFPPMGLPPMSQRPPAIPPMPPGILPPML-----------PPMGAP--- 43
PPP P PP PP+G PP PP PP P +LPP L PP+ P
Sbjct: 226 PPPPFPAGQTPPRPPLG-PPGPPGPPG-PPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283
Query: 44 ---PPLTQIPGMVPPMMPGMLMPAVPVTAATAP 73
PPL +P PP +PG P P P
Sbjct: 284 FGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGP 316
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 2/28 (7%)
Query: 186 PQPPQPQPDPPPVPPGP-TPVPTGLLEP 212
P PP PQ PPP PPGP P P G L P
Sbjct: 307 PGPPPPQQGPPP-PPGPFPPRPPGPLGP 333
Score = 32.7 bits (73), Expect = 1.5
Identities = 21/52 (40%), Positives = 23/52 (44%), Gaps = 9/52 (17%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAI--PPMPPGIL------PPMLPPMGAPPP 45
PPP +P P PP PP PA PP G+ PP P G PPP
Sbjct: 339 PPPHLPGP-PPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389
Score = 31.6 bits (70), Expect = 3.3
Identities = 28/117 (23%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 181 PQTLQPQPPQPQPDPPPVPPGP---TPVPTGLLEPEPGGSEDCDVLEAT---QPLEQGFL 234
PQ P PP P P PP P GP P L P PG + P G
Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371
Query: 235 QQLEEGPSSSGQHQPQQEEEESKPEPERSGLSWSNREKAKQAFKELL-RDKAVPSNA 290
GP + + + P + + ++ F+E++ R++A+ S+A
Sbjct: 372 TSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAISSSA 428
Score = 31.2 bits (69), Expect = 4.3
Identities = 25/62 (40%), Positives = 27/62 (43%), Gaps = 9/62 (14%)
Query: 188 PPQPQPDPPPVPPGPT-PVPTGLLEPEP-------GGSEDCDVLEATQPLEQGFLQQLEE 239
PP+P P PP PPGP P P G + P P G VL QP Q L L
Sbjct: 236 PPRP-PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294
Query: 240 GP 241
GP
Sbjct: 295 GP 296
Score = 31.2 bits (69), Expect = 4.3
Identities = 23/100 (23%), Positives = 48/100 (48%), Gaps = 5/100 (5%)
Query: 392 LAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPSFAQD---HQLQN 448
L K+ K A + I +L+ L G+ S ++ + + + D+ + H+ ++
Sbjct: 454 LIKQSKVSADDRCKVLISSLQDCLHGIESKSYGSGSRRERSRERDHSRSREKSRRHKSRS 513
Query: 449 MDKEDALICFEEHIRALEREEEEERERARLRERRQQRKNR 488
D+ D + E R ER + +R+R R R+R ++ ++R
Sbjct: 514 RDRHDDY--YRERSRERERHRDRDRDRDRERDREREYRHR 551
Score = 30.8 bits (68), Expect = 5.6
Identities = 18/41 (43%), Positives = 18/41 (43%), Gaps = 8/41 (19%)
Query: 184 LQPQPPQPQP-----DPPPVPPGP---TPVPTGLLEPEPGG 216
L P PP P P PPP PP P P P G P P G
Sbjct: 289 LGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 57.4 bits (137), Expect = 6e-08
Identities = 67/226 (29%), Positives = 82/226 (36%), Gaps = 54/226 (23%)
Query: 2 PPPGIPP-PFPPMGLPPMSQRPPA--IPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMP 58
PPP PP P PP LPP S PP PP PP + PP LP PP + PP++P
Sbjct: 403 PPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP 462
Query: 59 GMLM------PAVPVTAA-----------TAPGADTASSAVAGTGPPRALWSEHVAPDGR 101
P P A T+P T S+A GPP S VAP
Sbjct: 463 ATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATG--GPPED--SPTVAPKST 518
Query: 102 IYYYNADDKQSVWEKPSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDL 161
+ N +Q + S S+ + + P + D KP + + S RP
Sbjct: 519 TFLKNI--RQFIMPVVSARSSR----VIKTPRRFMDEDPPKP----PKVEVSPVLRPPIT 568
Query: 162 DDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVP-PGPTPVP 206
V PQ P P P PP P P TPVP
Sbjct: 569 TSPPV-------------------PQEPAPVPSPPRAPTPPSTPVP 595
Score = 41.6 bits (96), Expect = 0.003
Identities = 98/388 (25%), Positives = 130/388 (33%), Gaps = 77/388 (19%)
Query: 2 PPPGIPPPFP----PMGLPPMSQRPPAIP-PMPPGILPPMLPPMGAPPPLTQI---PGMV 53
PP PP P P+ PP + PP+ P P+P + P LT+ P
Sbjct: 565 PPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA 624
Query: 54 PPMMPGMLMPAVPVTAATAPGADTASSAVAGTG----------PPRALWSEHVAPDGRIY 103
PP P P P T++ P A PP E P+
Sbjct: 625 PPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPP-- 682
Query: 104 YYNADDKQSVWEKPSVLKSKAELL-----LSQCPWKEYKSDTGKPYYYNNQSKESRWTRP 158
ADD + E +V ++ L + P K S G P N +++ +P
Sbjct: 683 --PADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQP 740
Query: 159 KDLDDLEVLVKQEAAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLE-----PE 213
L+ L Q Q LPQ L PPQPQ PPP P P+ + P
Sbjct: 741 -----LQAL--------QTQLLPQALP--PPQPQLQPPPSPQQMPPLEKARIAGVGSLPL 785
Query: 214 PGGSEDC-------------------DVLEATQPLEQGFLQQLEEGPSSSGQ---HQPQQ 251
G E + A+ PL G Q+EE + Q P +
Sbjct: 786 SGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPG--GQMEEVAGAVKQISDRGPVR 843
Query: 252 EEEESKPEPERSGLSWSNREKAKQAFKELLRDKAVPSNASWEQAMKMVVTD-PRYSALPK 310
E+ES E +R S K + R AV + QA MV D PR SALP
Sbjct: 844 SEDES-VEAKRERPSGPESPVQGPRIKHVCRHAAV----ALGQARAMVPEDVPRLSALPL 898
Query: 311 LSEKKQAFNAYKAQREKEEKEEARLRAK 338
+ A + E E R K
Sbjct: 899 RDRQDLATEDTSSASETESVPSRSRRGK 926
Score = 39.3 bits (90), Expect = 0.016
Identities = 60/268 (22%), Positives = 90/268 (33%), Gaps = 71/268 (26%)
Query: 1 MPPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMG----APPPLTQIPGMVPPM 56
+PPP PP PP +S P +PPG L +LP +G APPP PP
Sbjct: 2211 VPPPVKQPPLPPT----ISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP--------PPP 2258
Query: 57 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 116
+++ + P + S +G PP AP +D ++ +
Sbjct: 2259 PLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP--------APPPYKAPRLDEDGEASEDT 2310
Query: 117 PSVLKSKAELLLSQCPWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLEVLVKQEAAGKQ 176
P V P + R P L++ E AG++
Sbjct: 2311 PQV-----------------------PGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEE 2347
Query: 177 QQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQ 236
Q P P P+ PP VP GP P LLE +
Sbjct: 2348 SPGPLQERSPLLPLPEDGPPQVPDGP---PDLLLESQ---------------------WH 2383
Query: 237 LEEGPSSSGQHQPQQEEEESKPEPERSG 264
G +SS + +P +++ P+R+G
Sbjct: 2384 HYSGEASSSEEEPPSPDDKENQAPKRTG 2411
Score = 36.2 bits (82), Expect = 0.13
Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 7/79 (8%)
Query: 181 PQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEG 240
P + P PP P PPPV P P P P P P E+ + E+ P+ +
Sbjct: 419 PPSTSPPPPLCPPPPPPVSPPPLPSP-----PPPPAQEEQE--ESPPPVVPATCSRKRGR 471
Query: 241 PSSSGQHQPQQEEEESKPE 259
P + + ++E + PE
Sbjct: 472 PPLTPSQRAEREAARAGPE 490
Score = 35.4 bits (80), Expect = 0.23
Identities = 51/223 (22%), Positives = 74/223 (33%), Gaps = 50/223 (22%)
Query: 17 PMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLMPAVPVTAATAPGAD 76
P +++ A P PP P PP PPP T P PP+ P P P + P
Sbjct: 392 PAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP---PPLCPPPPPPVSPPPLPSPP--- 445
Query: 77 TASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEKPSVLKSKAELLLSQC----- 131
PP A + +P + A + P +AE ++
Sbjct: 446 ----------PPPAQEEQEESPPPVV---PATCSRKRGRPPLTPSQRAEREAARAGPEGT 492
Query: 132 --PWKEYKSDTGKPYYYNNQSKESRWTRPKDLDDLE---------VLVKQEAAGKQQQQL 180
P + TG P ++S PK L+ V + K ++
Sbjct: 493 SPPTPTPSTATGGP------PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRF 546
Query: 181 PQTLQPQPPQPQPDP---------PPVPPGPTPVPTGLLEPEP 214
P+PP+ + P PPVP P PVP+ P P
Sbjct: 547 MDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP 589
Score = 35.0 bits (79), Expect = 0.30
Identities = 26/89 (29%), Positives = 32/89 (35%), Gaps = 22/89 (24%)
Query: 172 AAGKQQQQLPQTLQPQPPQPQPDPPPVPPGPTPVPTGLLEPEPGGSEDCDVLEATQPLEQ 231
AA K++ +LP PP P P PP PP +P P P P
Sbjct: 393 AAEKEEAKLPPP-PLTPPAPSPPPPLPPPSTSPPPPLCPPPPP----------------- 434
Query: 232 GFLQQLEEGPSSSGQHQPQQEEEESKPEP 260
+ P S P QEE+E P P
Sbjct: 435 ----PVSPPPLPSPPPPPAQEEQEESPPP 459
Score = 35.0 bits (79), Expect = 0.30
Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 33/112 (29%)
Query: 1 MPPPGIP------------PPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQ 48
+P PG P P FP P S+RP + P PP P A PPL
Sbjct: 1885 LPSPGSPSSLTHHIPTVGDPDFPAP--PRRSRRPSPLAPRPP-------PSRWASPPLKT 1935
Query: 49 IPGM-VPPMMPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPD 99
P + VPP P VTA T + A A + PP E + PD
Sbjct: 1936 SPQLRVPP-------PTSVVTALTPTSGELAPPGPAPSPPP----PEDLGPD 1976
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 56.6 bits (135), Expect = 1e-07
Identities = 28/59 (47%), Positives = 30/59 (50%), Gaps = 4/59 (6%)
Query: 2 PPPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGM 60
PPP PPP PP P S PP PP PP P P G PPP PG+ PP PG+
Sbjct: 682 PPPPPPPPLPP----PSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGL 736
Score = 51.2 bits (121), Expect = 4e-06
Identities = 50/183 (27%), Positives = 75/183 (40%), Gaps = 38/183 (20%)
Query: 2 PPPGIPPPFPPM-----------GLPPMSQRPPAIPPMPPGILPPMLPPMGA----PPPL 46
PPP PP PP+ +PP+S PP PP PP PP+ PP A PPP
Sbjct: 647 PPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPP--PPLPPPSSAGPPPPPPP 704
Query: 47 TQIPGMVPPMMPGMLMPAVPVTAATAP-------GADTASS------AVAGTGPPRALWS 93
+P P PG PA P P G ++SS A+ + P + L+
Sbjct: 705 PPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKPLYW 764
Query: 94 EHVAPDGRIYYYNADDKQSVW---EKPSVL-KSKAELLLSQCPWKEYKSDTGKPYYYNNQ 149
+ R + + ++W E+P + S+ E L S+ ++ K + Y N+
Sbjct: 765 TRIQISDR----SQNATPTLWDSLEEPDIRDPSEFEYLFSKDTTQQKKKPLSETYEKKNK 820
Query: 150 SKE 152
K+
Sbjct: 821 VKK 823
Score = 38.5 bits (88), Expect = 0.027
Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 4/35 (11%)
Query: 186 PQPPQPQPDP----PPVPPGPTPVPTGLLEPEPGG 216
P PP P P P PP PP P P+P P PGG
Sbjct: 684 PPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGG 718
Score = 33.9 bits (76), Expect = 0.66
Identities = 17/38 (44%), Positives = 17/38 (44%), Gaps = 2/38 (5%)
Query: 181 PQTLQPQPPQPQPDPPPVPPGPTPV--PTGLLEPEPGG 216
P P PP P PP P GP P P GL P P G
Sbjct: 698 PPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPG 735
Score = 31.2 bits (69), Expect = 4.3
Identities = 21/61 (34%), Positives = 23/61 (37%), Gaps = 4/61 (6%)
Query: 172 AAGKQQQQLPQTLQPQPPQPQP-DPPPVPPGP---TPVPTGLLEPEPGGSEDCDVLEATQ 227
+AG P L P P P PPP PP P P P GL S C A +
Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAIE 754
Query: 228 P 228
P
Sbjct: 755 P 755
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 56.6 bits (135), Expect = 1e-07
Identities = 48/143 (33%), Positives = 58/143 (40%), Gaps = 34/143 (23%)
Query: 2 PPP-----GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPM 56
PPP GIPPP PP LP + PP PP+P G P +PP PPP PG +PP
Sbjct: 682 PPPLPGSAGIPPPPPP--LPGEAGMPPPPPPLPGG---PGIPP---PPPFPGGPG-IPPP 732
Query: 57 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 116
PGM MP P P A + P+ L+ V +
Sbjct: 733 PPGMGMPPPPPFGFGVPAAPVLPFGLT----PKKLYKPEVQ----------------LRR 772
Query: 117 PSVLKSKAELLLSQCPWKEYKSD 139
P+ K AE L C W + K D
Sbjct: 773 PNWSKLVAEDLSQDCFWTKVKED 795
Score = 37.0 bits (84), Expect = 0.078
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
PP +P P PP+ I P PP PP PPP PP +PG +
Sbjct: 564 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP------PPPPPLPGGVC 617
Query: 63 ----PAVPVTAATAPGADTASSAVAGTGPP 88
P++P A +P + A PP
Sbjct: 618 ISSPPSLPGGTAISPPPPLSGDATIPPPPP 647
Score = 34.7 bits (78), Expect = 0.39
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 183 TLQPQPPQP-----QPDPPPVPPGPTPVPTGLLEPEP 214
T+ P PP P P PPP PP P P+P G+ P
Sbjct: 585 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 621
Score = 31.6 bits (70), Expect = 3.3
Identities = 42/193 (21%), Positives = 76/193 (39%), Gaps = 42/193 (21%)
Query: 328 EEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD 387
+E ++ + + LQ L+Q ++ S E +V D K+ + +
Sbjct: 1030 DELAHVEKASRVSAENLQKNLDQMKKQISDV----------ERDVQNFPAATDEKDKFVE 1079
Query: 388 VLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-------F 440
+ K +EQ +LR M N +T + + +Y + +P F
Sbjct: 1080 KMTSFVKDAQEQYNKLR-------------MMHSNMETLYKELGEYFLFDPKKLSVEEFF 1126
Query: 441 AQDHQLQNMDKEDALICFEEHIRALEREEEEERERARL------RERRQQRKNREAFQTF 494
H +NM L +E+ + RE EE+ RA+L +ER ++++ RE
Sbjct: 1127 MDLHNFRNM----FLQAVKENQK--RRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDM 1180
Query: 495 LDELHETGQLHSM 507
E ETG + S+
Sbjct: 1181 NAEGDETGVMDSL 1193
Score = 30.4 bits (67), Expect = 7.3
Identities = 37/122 (30%), Positives = 46/122 (37%), Gaps = 28/122 (22%)
Query: 3 PPGIPPP------FPPMGLPPMSQRPPAIPPMPPGILPPM-------LPP-------MGA 42
PP P P PP P S PP PP PP PP+ PP +
Sbjct: 574 PPAPPLPGDSGTIIPPPPAPGDSTTPPP-PPPPPPPPPPLPGGVCISSPPSLPGGTAISP 632
Query: 43 PPPLT---QIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHV 96
PPPL+ IP PP+ G+ +P ++P A P SA PP S +
Sbjct: 633 PPPLSGDATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 691
Query: 97 AP 98
P
Sbjct: 692 PP 693
Score = 30.4 bits (67), Expect = 7.3
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 188 PPQPQPDPPPVPPGPTPVPTGLLEPEPGGS 217
PP P P PPP PP P V PGG+
Sbjct: 599 PPPPPPPPPPPPPLPGGVCISSPPSLPGGT 628
Score = 30.4 bits (67), Expect = 7.3
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 186 PQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
P PP P P +PP P P+P G P P
Sbjct: 692 PPPPPPLPGEAGMPPPPPPLPGGPGIPPP 720
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 24/169 (14%)
Query: 186 PQPPQPQPDPPPVPPGPT-PVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSS 244
P PP P P P +PP P P G+ P PG + P GF P++
Sbjct: 705 PPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG-------MGMPPPPPFGF-----GVPAAP 752
Query: 245 GQHQPQQEEEESKPEPERSGLSWSN---REKAKQAFKELLRDKAVPSNASWEQAMKMVVT 301
++ KPE + +WS + ++ F +++ +N E K+ +T
Sbjct: 753 VLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENN---ELFAKLTLT 809
Query: 302 DPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAK--QTLQHFL 348
+SA K S+ K+ + ++ ++K+ L+ ++K Q L FL
Sbjct: 810 ---FSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 855
Score = 30.0 bits (66), Expect = 9.6
Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 186 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEP 214
P PP P P +PP P P+P G+ P P
Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 709
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 56.6 bits (135), Expect = 1e-07
Identities = 48/143 (33%), Positives = 58/143 (40%), Gaps = 34/143 (23%)
Query: 2 PPP-----GIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPM 56
PPP GIPPP PP LP + PP PP+P G P +PP PPP PG +PP
Sbjct: 691 PPPLPGSAGIPPPPPP--LPGEAGMPPPPPPLPGG---PGIPP---PPPFPGGPG-IPPP 741
Query: 57 MPGMLMPAVPVTAATAPGADTASSAVAGTGPPRALWSEHVAPDGRIYYYNADDKQSVWEK 116
PGM MP P P A + P+ L+ V +
Sbjct: 742 PPGMGMPPPPPFGFGVPAAPVLPFGLT----PKKLYKPEVQ----------------LRR 781
Query: 117 PSVLKSKAELLLSQCPWKEYKSD 139
P+ K AE L C W + K D
Sbjct: 782 PNWSKLVAEDLSQDCFWTKVKED 804
Score = 37.0 bits (84), Expect = 0.078
Identities = 26/90 (28%), Positives = 34/90 (37%), Gaps = 10/90 (11%)
Query: 3 PPGIPPPFPPMGLPPMSQRPPAIPPMPPGILPPMLPPMGAPPPLTQIPGMVPPMMPGMLM 62
PP +P P PP+ I P PP PP PPP PP +PG +
Sbjct: 573 PPSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP------PPPPPLPGGVC 626
Query: 63 ----PAVPVTAATAPGADTASSAVAGTGPP 88
P++P A +P + A PP
Sbjct: 627 ISSPPSLPGGTAISPPPPLSGDATIPPPPP 656
Score = 34.7 bits (78), Expect = 0.39
Identities = 16/37 (43%), Positives = 19/37 (51%), Gaps = 5/37 (13%)
Query: 183 TLQPQPPQP-----QPDPPPVPPGPTPVPTGLLEPEP 214
T+ P PP P P PPP PP P P+P G+ P
Sbjct: 594 TIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSP 630
Score = 31.6 bits (70), Expect = 3.3
Identities = 42/193 (21%), Positives = 76/193 (39%), Gaps = 42/193 (21%)
Query: 328 EEKEEARLRAKEAKQTLQHFLEQHERMTSTTRYRRAEQTFGELEVWAVVPERDRKEVYDD 387
+E ++ + + LQ L+Q ++ S E +V D K+ + +
Sbjct: 1039 DELAHVEKASRVSAENLQKNLDQMKKQISDV----------ERDVQNFPAATDEKDKFVE 1088
Query: 388 VLFFLAKKEKEQAKQLRRRNIQALKSILDGMSSVNFQTTWSQAQQYLMDNPS-------F 440
+ K +EQ +LR M N +T + + +Y + +P F
Sbjct: 1089 KMTSFVKDAQEQYNKLR-------------MMHSNMETLYKELGEYFLFDPKKLSVEEFF 1135
Query: 441 AQDHQLQNMDKEDALICFEEHIRALEREEEEERERARL------RERRQQRKNREAFQTF 494
H +NM L +E+ + RE EE+ RA+L +ER ++++ RE
Sbjct: 1136 MDLHNFRNM----FLQAVKENQK--RRETEEKMRRAKLAKEKAEKERLEKQQKREQLIDM 1189
Query: 495 LDELHETGQLHSM 507
E ETG + S+
Sbjct: 1190 NAEGDETGVMDSL 1202
Score = 30.4 bits (67), Expect = 7.3
Identities = 37/122 (30%), Positives = 46/122 (37%), Gaps = 28/122 (22%)
Query: 3 PPGIPPP------FPPMGLPPMSQRPPAIPPMPPGILPPM-------LPP-------MGA 42
PP P P PP P S PP PP PP PP+ PP +
Sbjct: 583 PPAPPLPGDSGTIIPPPPAPGDSTTPPP-PPPPPPPPPPLPGGVCISSPPSLPGGTAISP 641
Query: 43 PPPLT---QIPGMVPPMMPGMLMP---AVPVTAATAPGADTASSAVAGTGPPRALWSEHV 96
PPPL+ IP PP+ G+ +P ++P A P SA PP S +
Sbjct: 642 PPPLSGDATIP-PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGI 700
Query: 97 AP 98
P
Sbjct: 701 PP 702
Score = 30.4 bits (67), Expect = 7.3
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 188 PPQPQPDPPPVPPGPTPVPTGLLEPEPGGS 217
PP P P PPP PP P V PGG+
Sbjct: 608 PPPPPPPPPPPPPLPGGVCISSPPSLPGGT 637
Score = 30.4 bits (67), Expect = 7.3
Identities = 13/29 (44%), Positives = 15/29 (51%)
Query: 186 PQPPQPQPDPPPVPPGPTPVPTGLLEPEP 214
P PP P P +PP P P+P G P P
Sbjct: 701 PPPPPPLPGEAGMPPPPPPLPGGPGIPPP 729
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/169 (23%), Positives = 70/169 (41%), Gaps = 24/169 (14%)
Query: 186 PQPPQPQPDPPPVPPGPT-PVPTGLLEPEPGGSEDCDVLEATQPLEQGFLQQLEEGPSSS 244
P PP P P P +PP P P G+ P PG + P GF P++
Sbjct: 714 PPPPPPLPGGPGIPPPPPFPGGPGIPPPPPG-------MGMPPPPPFGF-----GVPAAP 761
Query: 245 GQHQPQQEEEESKPEPERSGLSWSN---REKAKQAFKELLRDKAVPSNASWEQAMKMVVT 301
++ KPE + +WS + ++ F +++ +N E K+ +T
Sbjct: 762 VLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFENN---ELFAKLTLT 818
Query: 302 DPRYSALPKLSEKKQAFNAYKAQREKEEKEEARLRAKEAK--QTLQHFL 348
+SA K S+ K+ + ++ ++K+ L+ ++K Q L FL
Sbjct: 819 ---FSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFL 864
Score = 30.0 bits (66), Expect = 9.6
Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 2/31 (6%)
Query: 186 PQPPQPQPDPPPVPPGPTPVP--TGLLEPEP 214
P PP P P +PP P P+P G+ P P
Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPP 718
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,853,095
Number of Sequences: 37866
Number of extensions: 2786314
Number of successful extensions: 61092
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 832
Number of HSP's successfully gapped in prelim test: 1605
Number of HSP's that attempted gapping in prelim test: 23273
Number of HSP's gapped (non-prelim): 23812
length of query: 858
length of database: 18,247,518
effective HSP length: 111
effective length of query: 747
effective length of database: 14,044,392
effective search space: 10491160824
effective search space used: 10491160824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.