Guide to the Human Genome
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Search of human proteins with 122937193

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|122937193 DNB5 [Homo sapiens]
         (748 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|122937193 DNB5 [Homo sapiens]                                     1515   0.0  
gi|122937259 solute carrier family 45, member 4 [Homo sapiens]        358   1e-98
gi|61635915 membrane-associated transporter protein isoform a [H...   217   4e-56
gi|61636000 membrane-associated transporter protein isoform b [H...   217   4e-56
gi|14916437 prostein [Homo sapiens]                                   111   3e-24
gi|56549694 enabled homolog isoform a [Homo sapiens]                   44   7e-04
gi|39930375 enabled homolog isoform b [Homo sapiens]                   44   7e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    39   0.013
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    39   0.013
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s...    39   0.013
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    39   0.013
gi|47132519 Ras association and pleckstrin homology domains 1 is...    38   0.039
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    37   0.067
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    37   0.067
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    37   0.087
gi|151301053 RNA binding motif protein 33 [Homo sapiens]               37   0.087
gi|85815829 SH3-domain binding protein 1 [Homo sapiens]                37   0.087
gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote...    36   0.11 
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    36   0.15 
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        36   0.15 
gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]        36   0.15 
gi|56676337 transmembrane protein 28 [Homo sapiens]                    36   0.15 
gi|163965366 nascent polypeptide-associated complex alpha subuni...    35   0.19 
gi|33356148 formin-like 1 [Homo sapiens]                               35   0.19 
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    35   0.25 
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]      35   0.25 
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]       35   0.25 
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   35   0.33 
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   35   0.33 
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   35   0.33 

>gi|122937193 DNB5 [Homo sapiens]
          Length = 748

 Score = 1515 bits (3922), Expect = 0.0
 Identities = 748/748 (100%), Positives = 748/748 (100%)

Query: 1   MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP 60
           MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP
Sbjct: 1   MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP 60

Query: 61  PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ 120
           PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ
Sbjct: 61  PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ 120

Query: 121 LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI 180
           LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI
Sbjct: 121 LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI 180

Query: 181 ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL 240
           ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL
Sbjct: 181 ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL 240

Query: 241 GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR 300
           GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR
Sbjct: 241 GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR 300

Query: 301 AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG 360
           AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG
Sbjct: 301 AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG 360

Query: 361 ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE 420
           ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE
Sbjct: 361 ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE 420

Query: 421 GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ 480
           GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ
Sbjct: 421 GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ 480

Query: 481 QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM 540
           QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM
Sbjct: 481 QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM 540

Query: 541 LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF 600
           LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF
Sbjct: 541 LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF 600

Query: 601 LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660
           LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK
Sbjct: 601 LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660

Query: 661 FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC 720
           FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC
Sbjct: 661 FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC 720

Query: 721 LYSSLFVIYEIPPSDAADEEHRPLLLNV 748
           LYSSLFVIYEIPPSDAADEEHRPLLLNV
Sbjct: 721 LYSSLFVIYEIPPSDAADEEHRPLLLNV 748


>gi|122937259 solute carrier family 45, member 4 [Homo sapiens]
          Length = 798

 Score =  358 bits (919), Expect = 1e-98
 Identities = 234/674 (34%), Positives = 334/674 (49%), Gaps = 70/674 (10%)

Query: 113 LQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLL 172
           LQ GLP+Q YSL WF+SPILG +  PL+G+ SDRCT  +GRRRPFIL L +G L G++L 
Sbjct: 27  LQKGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGVALF 86

Query: 173 LNGRDIGIALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLN 232
           LNG  IG+AL DV      G++LTV GVV++DFSAD+ + P  AY++DV    +QD  LN
Sbjct: 87  LNGSAIGLALGDVPNRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALN 146

Query: 233 IHALLAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERP 292
           IHA  AGLGG  GYV+GG+ W +T  G     Q +V++ F A+  +V+  L L SI E  
Sbjct: 147 IHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIIFTVSVALHLFSIDEEQ 206

Query: 293 LRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLT---PKYG 349
             P  E+ A                 E G  D    H    F   +     L    P   
Sbjct: 207 YSPQQERSA----------------EEPGALDGGEPHGVPAFPDEVQSEHELALDYPDVD 250

Query: 350 SFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPD 409
              S+  S   + + A       +    I+       SY A P S  +       PR   
Sbjct: 251 IMRSKSDSALHVPDTALDLEPELLFLHDIEPSIFHDASYPATPRSTSQELAKTKLPRLAT 310

Query: 410 GF---YRQDRGLLEGR---------EGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTL 457
                 ++D  LL+            G+ T    G   RV   DT    +S  ++R +  
Sbjct: 311 FLKEAAKEDETLLDNHLNEAKVPNGSGSPTKDALGGYTRV---DTKPSATSSSMRRRRHA 367

Query: 458 AIPDAA------GGGGPETSRRRNVTFSQQVANILLNGVKYESELTGSSERAEQ------ 505
               A+      G  G    R R        A +L+   +  S+L    +R  Q      
Sbjct: 368 FRRQASSTFSYYGKLGSHCYRYRRAN-----AVVLIKPSRSMSDLYDMQKRQRQHRHRNQ 422

Query: 506 -----------------PLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFM 548
                              +V  L  ++  MP+ L  LC+ H L W S     +FYTDFM
Sbjct: 423 SGATTSSGDTESEEGEGETTVRLLWLSMLKMPRELMRLCLCHLLTWFSVIAEAVFYTDFM 482

Query: 549 GEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEK-LEEF-LSVRTL 606
           G+V+F+GDPKAP  S A+Q YN+GV MGCWG+ IYA + A  SA+L+K L+ + LSVR +
Sbjct: 483 GQVIFEGDPKAPSNSTAWQAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSVRVI 542

Query: 607 YFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSA 666
           Y +  L F +GT +  +  N+YV +    T GI+  ++   PY+LL  Y+  K++   S 
Sbjct: 543 YVLGTLGFSVGTAVMAMFPNVYVAMVTISTMGIVSMSISYCPYALLGQYHDIKQYIHHSP 602

Query: 667 DGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLF 726
             ++RG G+D ++LSCQ +++QILV+  LG +  AVG+   +   +S+ SFLG L ++  
Sbjct: 603 GNSKRGFGIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFL 662

Query: 727 VIYEIPPSDAADEE 740
           VIY     +A +E+
Sbjct: 663 VIYPNVSEEAKEEQ 676


>gi|61635915 membrane-associated transporter protein isoform a [Homo
           sapiens]
          Length = 530

 Score =  217 bits (552), Expect = 4e-56
 Identities = 111/238 (46%), Positives = 151/238 (63%), Gaps = 6/238 (2%)

Query: 80  PQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPL 139
           P+R    L+ +   +FG EF YA+E AYVTPVLL +GLP  LYS+VWF+SPILGFLLQP+
Sbjct: 28  PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPV 87

Query: 140 LGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIAL-ADVTGNHKWGLLLTVC 198
           +G+ SD C SR+GRRRP+IL L +  L+G++L LNG  +  AL A+      W + +T+ 
Sbjct: 88  VGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMI 147

Query: 199 GVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTGF 258
           GVVL DF+AD  D P  AY+ DVCS  D+++GL+ HAL  G GG  GY++G I W     
Sbjct: 148 GVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLEL 207

Query: 259 GRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPV 316
           GR LG + +V++ F+A+ L++   + L SI E PL        A   P    P  PP+
Sbjct: 208 GRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPL-----TEVAKGIPPQQTPQDPPL 260



 Score =  183 bits (465), Expect = 4e-46
 Identities = 89/235 (37%), Positives = 142/235 (60%), Gaps = 5/235 (2%)

Query: 500 SERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKA 559
           +E+  + +++  L   + NMP   R LC++H +GW +F   +LF+TDFMG++V++GDP +
Sbjct: 294 AEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYS 353

Query: 560 PHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTG 619
            H S  +  Y  GV +GCWG CI +  ++ YS   + L  ++ ++ LYF  YL FGLGTG
Sbjct: 354 AHNSTEFLIYERGVEVGCWGFCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTG 413

Query: 620 LATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYY-----QSKKFAGSSADGTRRGMG 674
              L  N+Y  L LC  +G++ STL T+P++L+ +Y+     + ++  G   D + RG G
Sbjct: 414 FIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKG 473

Query: 675 VDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVIY 729
           +D + L+C   LAQILV   LG L +  G+   V+  +S V+ +GC + +LFV Y
Sbjct: 474 MDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRY 528


>gi|61636000 membrane-associated transporter protein isoform b [Homo
           sapiens]
          Length = 460

 Score =  217 bits (552), Expect = 4e-56
 Identities = 111/238 (46%), Positives = 151/238 (63%), Gaps = 6/238 (2%)

Query: 80  PQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPL 139
           P+R    L+ +   +FG EF YA+E AYVTPVLL +GLP  LYS+VWF+SPILGFLLQP+
Sbjct: 28  PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPV 87

Query: 140 LGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIAL-ADVTGNHKWGLLLTVC 198
           +G+ SD C SR+GRRRP+IL L +  L+G++L LNG  +  AL A+      W + +T+ 
Sbjct: 88  VGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMI 147

Query: 199 GVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTGF 258
           GVVL DF+AD  D P  AY+ DVCS  D+++GL+ HAL  G GG  GY++G I W     
Sbjct: 148 GVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLEL 207

Query: 259 GRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPV 316
           GR LG + +V++ F+A+ L++   + L SI E PL        A   P    P  PP+
Sbjct: 208 GRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPL-----TEVAKGIPPQQTPQDPPL 260



 Score =  145 bits (366), Expect = 1e-34
 Identities = 62/161 (38%), Positives = 103/161 (63%)

Query: 500 SERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKA 559
           +E+  + +++  L   + NMP   R LC++H +GW +F   +LF+TDFMG++V++GDP +
Sbjct: 294 AEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYS 353

Query: 560 PHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTG 619
            H S  +  Y  GV +GCWG CI +  ++ YS   + L  ++ ++ LYF  YL FGLGTG
Sbjct: 354 AHNSTEFLIYERGVEVGCWGFCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTG 413

Query: 620 LATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660
              L  N+Y  L LC  +G++ STL T+P++L+ +Y++ ++
Sbjct: 414 FIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEE 454


>gi|14916437 prostein [Homo sapiens]
          Length = 553

 Score =  111 bits (277), Expect = 3e-24
 Identities = 75/226 (33%), Positives = 113/226 (50%), Gaps = 8/226 (3%)

Query: 86  ELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSD 145
           +LL    + FG+E   A    YV P+LL++G+ ++  ++V  I P+LG +  PLLG+ SD
Sbjct: 17  QLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASD 76

Query: 146 RCTSRFGRRRPFILVLAIGALLGLSLLLN-GRDIGIALADVTGNHKWGLLLTVCGVVLMD 204
               R+GRRRPFI  L++G LL L L+   G   G+   D        L L + GV L+D
Sbjct: 77  HWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPD---PRPLELALLILGVGLLD 133

Query: 205 FSADSADNPSHAYMMDVCSPADQDR-GLNIHALLAGLGGGFGYVVGGIHWDKTGFGRALG 263
           F       P  A + D+    D  R   +++A +  LGG  GY++  I WD +     LG
Sbjct: 134 FCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLG 193

Query: 264 GQLRVIY-LFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSL 308
            Q   ++ L T + L  T V   + + E     P+E    + +PSL
Sbjct: 194 TQEECLFGLLTLIFL--TCVAATLLVAEEAALGPTEPAEGLSAPSL 237



 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 55/171 (32%), Positives = 87/171 (50%)

Query: 511 RLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYN 570
           RL    C MP+ LR L V     W++     LFYTDF+GE ++QG P+A   +EA + Y+
Sbjct: 259 RLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYD 318

Query: 571 SGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTGLATLSRNLYVV 630
            GV MG  G+ +    +  +S ++++L +    R +Y  +  AF +  G   LS ++ VV
Sbjct: 319 EGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVV 378

Query: 631 LSLCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLS 681
            +     G  FS L  LPY+L   Y++ K+       G   G   + SL++
Sbjct: 379 TASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMT 429


>gi|56549694 enabled homolog isoform a [Homo sapiens]
          Length = 591

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 282 VLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF--SSPIS 339
           VL  ++ P  P  PP   +A++  P  P PP PP LP  GP    P     N     P  
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366

Query: 340 PPSPLTPKYGSFISRDSS----LTGIS 362
           PP+P  P  G F++  S     LTG++
Sbjct: 367 PPAPPLPASGFFLASMSEDNRPLTGLA 393


>gi|39930375 enabled homolog isoform b [Homo sapiens]
          Length = 570

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 282 VLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF--SSPIS 339
           VL  ++ P  P  PP   +A++  P  P PP PP LP  GP    P     N     P  
Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366

Query: 340 PPSPLTPKYGSFISRDSS----LTGIS 362
           PP+P  P  G F++  S     LTG++
Sbjct: 367 PPAPPLPASGFFLASMSEDNRPLTGLA 393


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 9/82 (10%)

Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSS---------PISPPSPLT 345
           PPS+   ++ +P L +PPSPP  P   P  + P       ++         P +PP+  T
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525

Query: 346 PKYGSFISRDSSLTGISEFASS 367
           P   +  S  +S  G + F+ S
Sbjct: 526 PPLQALPSPPASFPGQAPFSPS 547



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 7/70 (10%)

Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLP----PSPPVLPEEGPGDSLPSHTA-TNFSSPI 338
           +L ++P  P  PPS+   ++ SP+L       PSPP+ P   P    P   A     +P 
Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409

Query: 339 SPPS--PLTP 346
           SPP+  PL+P
Sbjct: 410 SPPASPPLSP 419



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 14/75 (18%)

Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATN---------- 333
           L S P  PL  PP +   A+  P L  PPSPP  P   P  + PS  A N          
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPNALAVHLLQAP 439

Query: 334 FSSPISPP--SPLTP 346
           FS P SPP  +P +P
Sbjct: 440 FSPPPSPPVQAPFSP 454



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336
           S+P  PL  PP +    + +P L +PPSPP           P  GP  S+     T   +
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 608

Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367
           P  PP P      +    D  L G S  A+S
Sbjct: 609 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 637



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344
           L + P +  +PP +   A+ +P L   PSPP      PG +  S +A+   SP++ P P 
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQ 561

Query: 345 TP 346
            P
Sbjct: 562 AP 563



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 24/55 (43%), Positives = 25/55 (45%), Gaps = 6/55 (10%)

Query: 292 PLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHT--ATNFSSPISPPSPL 344
           PL PPS        PSL   PSPP  P      SL S T  AT+   P  P SPL
Sbjct: 339 PLAPPSPSAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 9/82 (10%)

Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSS---------PISPPSPLT 345
           PPS+   ++ +P L +PPSPP  P   P  + P       ++         P +PP+  T
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486

Query: 346 PKYGSFISRDSSLTGISEFASS 367
           P   +  S  +S  G + F+ S
Sbjct: 487 PPLQALPSPPASFPGQAPFSPS 508



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 7/70 (10%)

Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLP----PSPPVLPEEGPGDSLPSHTA-TNFSSPI 338
           +L ++P  P  PPS+   ++ SP+L       PSPP+ P   P    P   A     +P 
Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370

Query: 339 SPPS--PLTP 346
           SPP+  PL+P
Sbjct: 371 SPPASPPLSP 380



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 14/75 (18%)

Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATN---------- 333
           L S P  PL  PP +   A+  P L  PPSPP  P   P  + PS  A N          
Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPNALAVHLLQAP 400

Query: 334 FSSPISPP--SPLTP 346
           FS P SPP  +P +P
Sbjct: 401 FSPPPSPPVQAPFSP 415



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336
           S+P  PL  PP +    + +P L +PPSPP           P  GP  S+     T   +
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569

Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367
           P  PP P      +    D  L G S  A+S
Sbjct: 570 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 598



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%)

Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344
           L + P +  +PP +   A+ +P L   PSPP      PG +  S +A+   SP++ P P 
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQ 522

Query: 345 TP 346
            P
Sbjct: 523 AP 524



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 24/57 (42%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 292 PLRPPSEKRAAMKS--PSLPLPPSPPVLPEEGPGDSLPSHT--ATNFSSPISPPSPL 344
           PL  PS       S  PSL   PSPP  P      SL S T  AT+   P  P SPL
Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350


>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
           sapiens]
          Length = 468

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348
           P RP  P +E  +    P+LP+P +P   P   P    P    +    P+ PP P  P Y
Sbjct: 198 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA---PGRKGSIQDRPLPPPPPRLPGY 254

Query: 349 G 349
           G
Sbjct: 255 G 255


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 39.3 bits (90), Expect = 0.013
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348
           P RP  P +E  +    P+LP+P +P   P   P    P    +    P+ PP P  P Y
Sbjct: 291 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA---PGRKGSIQDRPLPPPPPRLPGY 347

Query: 349 G 349
           G
Sbjct: 348 G 348


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 3/70 (4%)

Query: 276 TLSVTTVLTLVSIPE-RPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF 334
           T +V  V+T  + P   P  PP++K+ A   P+  +PPSPP  P   P  +LP   +   
Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAF--PASYIPPSPPTPPVPVPPPTLPKQQSFCA 848

Query: 335 SSPISPPSPL 344
             P SP SP+
Sbjct: 849 KPPPSPLSPV 858



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 13/71 (18%)

Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGD-------SLPSHTATNFSSPI- 338
           S P  PL+    +     +P  P PP PP +P   P         ++P+ T+T   +P+ 
Sbjct: 741 SAPPPPLKIHQVQHITQVAP--PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798

Query: 339 ---SPPSPLTP 346
              +PP+P  P
Sbjct: 799 TQAAPPTPTPP 809



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 23/75 (30%), Positives = 27/75 (36%), Gaps = 4/75 (5%)

Query: 286 VSIPERPLRPPSEKRAAMKSPSLPLP-PSPPVLPEEGP---GDSLPSHTATNFSSPISPP 341
           V  P+ P  PP         P  P+P P PP  P   P       P    +  SSP    
Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970

Query: 342 SPLTPKYGSFISRDS 356
            P TP+  S I   S
Sbjct: 971 PPPTPQRNSSIKSSS 985


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 2/51 (3%)

Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSP--ISPPSP 343
           PPS+   ++ +P L +PPSPP  P   P  + P       ++P    PPSP
Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 25/59 (42%), Positives = 29/59 (49%), Gaps = 6/59 (10%)

Query: 291 RPLRPPSEKRAAMKSPSLPLPPSPPV---LPEEGPGDSLPSHTATNFSSPISPPSPLTP 346
           RP+ PP    AA   P+  LPPSPP+   LP   P  S P    T  S P +PPS   P
Sbjct: 315 RPVPPPDN--AATPLPAT-LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%)

Query: 287 SIPERPL-RPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLT 345
           S+P  PL +PP +   A+ +P L   PSPP      PG +  S +A+   SP++ P P  
Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQA 831

Query: 346 P 346
           P
Sbjct: 832 P 832



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 10/63 (15%)

Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPI--SPP 341
           +L ++P  P  PPS+   +M +P +  PPS   +P        P     + +SP   +PP
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--------PIQVPHSLTSPSLQAPP 404

Query: 342 SPL 344
           SPL
Sbjct: 405 SPL 407



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%)

Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336
           S+P  PL  PP +    + +P L +PPSPP           P  GP  S+     T   +
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877

Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367
           P  PP P      +    D  L G S  A+S
Sbjct: 878 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 906



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%)

Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSP--ISPPSP 343
           PP +    + +P L +PPSPP  P   P  + P       ++P    PPSP
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 6/64 (9%)

Query: 289 PERP---LRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTA-TNFSSPISPPS-- 342
           PE P     PP +   A+ SP L   PSPP+ P   P    P   A     +P SPP+  
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 343 PLTP 346
           PL+P
Sbjct: 641 PLSP 644



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 12/74 (16%)

Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPP----VLPEEGPGDSLPSHTATN-----F 334
           L S P  PL  PP +    +  P L  PPSPP    + P   P    P+  A +     F
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 335 SSPISPP--SPLTP 346
           S P SPP  +P +P
Sbjct: 666 SPPPSPPVQAPFSP 679



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 1/79 (1%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348
           P  P  PP    A       PL  +PP+     P  SLP         P +PP+  TP  
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK-PPPQAPPALATPPL 797

Query: 349 GSFISRDSSLTGISEFASS 367
            +  S  +S  G + F+ S
Sbjct: 798 QALPSPPASFPGQAPFSPS 816


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 49/213 (23%), Positives = 78/213 (36%), Gaps = 27/213 (12%)

Query: 313 SPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISR-DSSLTGISEFASS--FG 369
           SPP  P + PG  LP        SP++PP+PL        S+  ++   +S  ASS  FG
Sbjct: 271 SPPQKPSQSPGHGLP--------SPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFG 322

Query: 370 TA--NIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQ--DRGLLEGREGA 425
            A  ++  V     T      +     +P P  S        G   Q     LL   +G 
Sbjct: 323 NALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQ 382

Query: 426 LTSGCDGD----ILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQQ 481
           + +   G+    ++    +  S  +    L +P   ++  AA  G          + SQ 
Sbjct: 383 IIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQS 442

Query: 482 VANILLNGVKYESELTGSSERAEQPLSVGRLCS 514
                      ++  + SS  +   LSVG+L S
Sbjct: 443 PVR--------QASSSSSSSSSSSALSVGQLVS 467


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 36.6 bits (83), Expect = 0.087
 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 8/68 (11%)

Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPP--SPPVL---PEEGPGDSLPSHTATNF---SSPI 338
           ++P +P RPP+   A  ++P LP PP   PP +    EE P   L S     +      +
Sbjct: 879 ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938

Query: 339 SPPSPLTP 346
            PP+PL P
Sbjct: 939 QPPTPLLP 946


>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
          Length = 1170

 Score = 36.6 bits (83), Expect = 0.087
 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 17/67 (25%)

Query: 290 ERPLRPP------------SEKRAAMKSPSLPLPPSPPVLPEEGPGDS-LPSHTATNFSS 336
           ERP+RP             S+  +A   P +P  P  P LP  GPG   LP+HT  N   
Sbjct: 525 ERPVRPALQPPGPVGILHFSQPGSATTRPFIP--PRQPFLP--GPGQPFLPTHTQPNLQG 580

Query: 337 PISPPSP 343
           P+ PP P
Sbjct: 581 PLHPPLP 587


>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
          Length = 701

 Score = 36.6 bits (83), Expect = 0.087
 Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 13/127 (10%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSH-TATNFSSPISPPSPLTPK 347
           P RP  PP +   +  SP  P PP PP     G   +LP     ++  +P  PP PL P 
Sbjct: 570 PARPTMPPPQVSGSRSSP--PAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPP-PLPPT 626

Query: 348 YGSFISRDSSLTGISEFASSFGTA--------NIDSVLIDCFTGGHDSYLAIPGSVPRPP 399
                 R S  +  S   +S G A        N   V +   T    +  AI G VP PP
Sbjct: 627 PPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISG-VPTPP 685

Query: 400 ISVSFPR 406
                PR
Sbjct: 686 AIPPQPR 692


>gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein
           1 [Homo sapiens]
          Length = 828

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 10/78 (12%)

Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPI--SPPSPL 344
           S P RP  P    R+    P  P PPS P LP   PG       +  FS PI  S P P+
Sbjct: 441 SSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPG---VGDVSRPFSPPIHSSSPPPI 497

Query: 345 TPKYGSFISRDSSLTGIS 362
            P     ++R  S + IS
Sbjct: 498 AP-----LARAESTSSIS 510



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%)

Query: 297 SEKRAAMKSPSLPLPPSPP----VLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346
           S K   +   + P PP PP    V+   GPG      T +  SSP  P +PL P
Sbjct: 399 SPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVP 452


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%)

Query: 292 PLRPPSEKRAAMKSP--SLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346
           P  PPS    A+  P  +   PP PP LP   P    P   +     P++PP P  P
Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 11/81 (13%)

Query: 289 PERPLRPPSEKRAA--MKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346
           P  P  PP +      M  PS+P PP PPV+P++      P ++  NF     PP    P
Sbjct: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF-----PP----P 180

Query: 347 KYGSFISRDSSLTGISEFASS 367
            + SF +  SS    +  +SS
Sbjct: 181 SFNSFQNNPSSFLPSANNSSS 201


>gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens]
          Length = 1374

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 11/81 (13%)

Query: 289 PERPLRPPSEKRAA--MKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346
           P  P  PP +      M  PS+P PP PPV+P++      P ++  NF     PP    P
Sbjct: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF-----PP----P 180

Query: 347 KYGSFISRDSSLTGISEFASS 367
            + SF +  SS    +  +SS
Sbjct: 181 SFNSFQNNPSSFLPSANNSSS 201


>gi|56676337 transmembrane protein 28 [Homo sapiens]
          Length = 472

 Score = 35.8 bits (81), Expect = 0.15
 Identities = 51/190 (26%), Positives = 69/190 (36%), Gaps = 39/190 (20%)

Query: 293 LRPP----SEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348
           +RPP     E++       LPLPP PP  P   PG   P ++    ++P +   P+    
Sbjct: 78  MRPPWGAGRERQPVPPRAVLPLPPPPPGEPSAPPGTCGPRYSNLTKAAPAAGSRPVCGGV 137

Query: 349 GSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAP 408
                 D++ T +      F                       P    RPP S+S  RAP
Sbjct: 138 PEPTGLDAACTKLQSLQRLFEPTT-------------------PAPPLRPPDSLS--RAP 176

Query: 409 DGFYRQDRGLLEGREGALT-SGCD----GDIL----RVGSLDTSKPRSSGILKRPQTLAI 459
             F    + LL+G     T S CD     D+L    R  SLD S     G L     LA+
Sbjct: 177 AEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLMGDL-----LAV 231

Query: 460 PDAAGGGGPE 469
             + G G  E
Sbjct: 232 VASPGSGAWE 241


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 3/75 (4%)

Query: 273  TAVTLSVTTVLTLVSIPERPLRPPSEK-RAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTA 331
            TA  LS  T  TL   P+  L PP+    +  K+P++P P   P  P      S P+ T 
Sbjct: 1530 TATLLSKKTPATLA--PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587

Query: 332  TNFSSPISPPSPLTP 346
            + +    SP   L P
Sbjct: 1588 STYKGAPSPKELLIP 1602



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 20/81 (24%)

Query: 289  PERPLRPPSEKRAAMKSPSLPLPPSPPVL----PEEGPGDSLPSHTATNFSSPISP---- 340
            P+  L PP     A+ SPS    P+PP +    PE+GP    P  T T  S P++P    
Sbjct: 1596 PKELLIPP-----AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT--SPPVTPSSLK 1648

Query: 341  -----PSPLTPKYGSFISRDS 356
                 P+ +T K G+ + + S
Sbjct: 1649 DSPTSPASVTCKMGATVPQAS 1669



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%)

Query: 289  PERPLRPPSEKRAAM-----KSPSLPLPPSPPVLPEEGPGD--SLPSHTATNFSSPISPP 341
            P  P  PP+ K+ A      K+P+ P P   P LP   P     +P+ T ++   PI+P 
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIAPT 1530

Query: 342  SPLTPK 347
            + L  K
Sbjct: 1531 ATLLSK 1536


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 20/62 (32%), Positives = 23/62 (37%)

Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344
           L  +P     PPS    A   P  P PP  P LP + P    P         P+ PP P 
Sbjct: 548 LPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPP 607

Query: 345 TP 346
            P
Sbjct: 608 PP 609


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 54/195 (27%), Positives = 64/195 (32%), Gaps = 32/195 (16%)

Query: 286  VSIPERPLRPPSEKRAAMKSP----------SLPLPPSPPVLPEEGPGDSLPSHTATNFS 335
            + +PE  L PP   R+   SP          SL L   P   PE  P    P       S
Sbjct: 952  LGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGAS 1011

Query: 336  SPISPPSPLTPKYGSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSV 395
               SP    TP+            G+S    S G            +G H S L  P S 
Sbjct: 1012 GGASPVG-FTPR-----------GGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASS 1059

Query: 396  PRP---PISVSFPRAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDTSKPRSSGILK 452
            P P   P     P    G   QD  L+   + AL    DG      +L  + P SSG   
Sbjct: 1060 PPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQ--DG----AQTLRRASPHSSGESM 1113

Query: 453  RPQTLAIPDAAGGGG 467
                L  P A GG G
Sbjct: 1114 AAFPL-FPRAGGGSG 1127


>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
          Length = 733

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 19/157 (12%)

Query: 288 IPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPK 347
           +P RP  PPS   AA K P L LP  PP+  ++    + PS      S    P  P  P 
Sbjct: 264 LPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPD 323

Query: 348 YGSFISR-DSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVS-FP 405
             S + R      G+  +    G     S    C   G D+ ++ PG    PP+ ++  P
Sbjct: 324 GPSLLYRWMKHEPGLGSYGDELGRER-GSPSERCEERGGDAAVS-PGG---PPLGLAPPP 378

Query: 406 RAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDT 442
           R P        G L+G  GA   G DGD  +  S +T
Sbjct: 379 RYP--------GSLDG-PGA---GGDGDDYKSSSEET 403


>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
          Length = 714

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 19/157 (12%)

Query: 288 IPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPK 347
           +P RP  PPS   AA K P L LP  PP+  ++    + PS      S    P  P  P 
Sbjct: 245 LPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPD 304

Query: 348 YGSFISR-DSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVS-FP 405
             S + R      G+  +    G     S    C   G D+ ++ PG    PP+ ++  P
Sbjct: 305 GPSLLYRWMKHEPGLGSYGDELGRER-GSPSERCEERGGDAAVS-PGG---PPLGLAPPP 359

Query: 406 RAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDT 442
           R P        G L+G  GA   G DGD  +  S +T
Sbjct: 360 RYP--------GSLDG-PGA---GGDGDDYKSSSEET 384


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334
           T  T+ S P  P  P P+  ++A  +P  P P     P+P    E  P  +      T  
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292

Query: 335 SSPISP--PSPLTPK 347
           S+P +P  P+P TPK
Sbjct: 293 SAPTTPKEPAPTTPK 307



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340
           PE P  P + K AA  +P  P P +P    P  P+E P  + P  TA       +P    
Sbjct: 527 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 584

Query: 341 -PSPLTPK 347
            P+P TPK
Sbjct: 585 EPAPTTPK 592



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%)

Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332
           TT  +  + P+ P  P + K  A  +P  P P +P    P  P+E P  + P     T T
Sbjct: 406 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 463

Query: 333 NFSSPISP--PSPLTPK 347
              +P +P  P+P TPK
Sbjct: 464 KKPAPTTPKEPAPTTPK 480



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%)

Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343
           P  P  P P+ K  A  +P  P P +P    P  P+E P  + P   A   +     PSP
Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 382

Query: 344 LTPK 347
            TPK
Sbjct: 383 TTPK 386



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342
           + L P + ++ A  +P  P P +P    P  PEE    +   P+ T    ++P +P  P+
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547

Query: 343 PLTPK 347
           P TPK
Sbjct: 548 PTTPK 552


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334
           T  T+ S P  P  P P+  ++A  +P  P P     P+P    E  P  +      T  
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333

Query: 335 SSPISP--PSPLTPK 347
           S+P +P  P+P TPK
Sbjct: 334 SAPTTPKEPAPTTPK 348



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340
           PE P  P + K AA  +P  P P +P    P  P+E P  + P  TA       +P    
Sbjct: 568 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 625

Query: 341 -PSPLTPK 347
            P+P TPK
Sbjct: 626 EPAPTTPK 633



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%)

Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332
           TT  +  + P+ P  P + K  A  +P  P P +P    P  P+E P  + P     T T
Sbjct: 447 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 504

Query: 333 NFSSPISP--PSPLTPK 347
              +P +P  P+P TPK
Sbjct: 505 KKPAPTTPKEPAPTTPK 521



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%)

Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343
           P  P  P P+ K  A  +P  P P +P    P  P+E P  + P   A   +     PSP
Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 423

Query: 344 LTPK 347
            TPK
Sbjct: 424 TTPK 427



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342
           + L P + ++ A  +P  P P +P    P  PEE    +   P+ T    ++P +P  P+
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588

Query: 343 PLTPK 347
           P TPK
Sbjct: 589 PTTPK 593


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 34.7 bits (78), Expect = 0.33
 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%)

Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334
           T  T+ S P  P  P P+  ++A  +P  P P     P+P    E  P  +      T  
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385

Query: 335 SSPISP--PSPLTPK 347
           S+P +P  P+P TPK
Sbjct: 386 SAPTTPKEPAPTTPK 400



 Score = 34.3 bits (77), Expect = 0.43
 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%)

Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340
           PE P  P + K AA  +P  P P +P    P  P+E P  + P  TA       +P    
Sbjct: 620 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 677

Query: 341 -PSPLTPK 347
            P+P TPK
Sbjct: 678 EPAPTTPK 685



 Score = 33.1 bits (74), Expect = 0.97
 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%)

Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332
           TT  +  + P+ P  P + K  A  +P  P P +P    P  P+E P  + P     T T
Sbjct: 499 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 556

Query: 333 NFSSPISP--PSPLTPK 347
              +P +P  P+P TPK
Sbjct: 557 KKPAPTTPKEPAPTTPK 573



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%)

Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343
           P  P  P P+ K  A  +P  P P +P    P  P+E P  + P   A   +     PSP
Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 475

Query: 344 LTPK 347
            TPK
Sbjct: 476 TTPK 479



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342
           + L P + ++ A  +P  P P +P    P  PEE    +   P+ T    ++P +P  P+
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640

Query: 343 PLTPK 347
           P TPK
Sbjct: 641 PTTPK 645


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,275,770
Number of Sequences: 37866
Number of extensions: 1661191
Number of successful extensions: 13538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 227
Number of HSP's that attempted gapping in prelim test: 11669
Number of HSP's gapped (non-prelim): 1937
length of query: 748
length of database: 18,247,518
effective HSP length: 110
effective length of query: 638
effective length of database: 14,082,258
effective search space: 8984480604
effective search space used: 8984480604
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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