BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|122937193 DNB5 [Homo sapiens] (748 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|122937193 DNB5 [Homo sapiens] 1515 0.0 gi|122937259 solute carrier family 45, member 4 [Homo sapiens] 358 1e-98 gi|61635915 membrane-associated transporter protein isoform a [H... 217 4e-56 gi|61636000 membrane-associated transporter protein isoform b [H... 217 4e-56 gi|14916437 prostein [Homo sapiens] 111 3e-24 gi|56549694 enabled homolog isoform a [Homo sapiens] 44 7e-04 gi|39930375 enabled homolog isoform b [Homo sapiens] 44 7e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.013 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 39 0.013 gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s... 39 0.013 gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa... 39 0.013 gi|47132519 Ras association and pleckstrin homology domains 1 is... 38 0.039 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 37 0.067 gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 37 0.067 gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 37 0.087 gi|151301053 RNA binding motif protein 33 [Homo sapiens] 37 0.087 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 37 0.087 gi|116235472 SH3-domain GRB2-like (endophilin) interacting prote... 36 0.11 gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 36 0.15 gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 36 0.15 gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] 36 0.15 gi|56676337 transmembrane protein 28 [Homo sapiens] 36 0.15 gi|163965366 nascent polypeptide-associated complex alpha subuni... 35 0.19 gi|33356148 formin-like 1 [Homo sapiens] 35 0.19 gi|4885407 hyperpolarization activated cyclic nucleotide-gated p... 35 0.25 gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 35 0.25 gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 35 0.25 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 35 0.33 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 35 0.33 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 35 0.33 >gi|122937193 DNB5 [Homo sapiens] Length = 748 Score = 1515 bits (3922), Expect = 0.0 Identities = 748/748 (100%), Positives = 748/748 (100%) Query: 1 MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP 60 MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP Sbjct: 1 MIPAASSTPPGDALFPSVAPQDFWRSQVTGYSGSVTRHLSHRANNFKRHPKRRKCIRPSP 60 Query: 61 PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ 120 PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ Sbjct: 61 PPPPNTPCPLELVDFGDLHPQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQ 120 Query: 121 LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI 180 LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI Sbjct: 121 LYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGI 180 Query: 181 ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL 240 ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL Sbjct: 181 ALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGL 240 Query: 241 GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR 300 GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR Sbjct: 241 GGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKR 300 Query: 301 AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG 360 AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG Sbjct: 301 AAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISRDSSLTG 360 Query: 361 ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE 420 ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE Sbjct: 361 ISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQDRGLLE 420 Query: 421 GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ 480 GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ Sbjct: 421 GREGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQ 480 Query: 481 QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM 540 QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM Sbjct: 481 QVANILLNGVKYESELTGSSERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGM 540 Query: 541 LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF 600 LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF Sbjct: 541 LLFYTDFMGEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEF 600 Query: 601 LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660 LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK Sbjct: 601 LSVRTLYFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660 Query: 661 FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC 720 FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC Sbjct: 661 FAGSSADGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGC 720 Query: 721 LYSSLFVIYEIPPSDAADEEHRPLLLNV 748 LYSSLFVIYEIPPSDAADEEHRPLLLNV Sbjct: 721 LYSSLFVIYEIPPSDAADEEHRPLLLNV 748 >gi|122937259 solute carrier family 45, member 4 [Homo sapiens] Length = 798 Score = 358 bits (919), Expect = 1e-98 Identities = 234/674 (34%), Positives = 334/674 (49%), Gaps = 70/674 (10%) Query: 113 LQMGLPDQLYSLVWFISPILGFLLQPLLGAWSDRCTSRFGRRRPFILVLAIGALLGLSLL 172 LQ GLP+Q YSL WF+SPILG + PL+G+ SDRCT +GRRRPFIL L +G L G++L Sbjct: 27 LQKGLPEQYYSLTWFLSPILGLIFTPLIGSASDRCTLSWGRRRPFILALCVGVLFGVALF 86 Query: 173 LNGRDIGIALADVTGNHKWGLLLTVCGVVLMDFSADSADNPSHAYMMDVCSPADQDRGLN 232 LNG IG+AL DV G++LTV GVV++DFSAD+ + P AY++DV +QD LN Sbjct: 87 LNGSAIGLALGDVPNRQPIGIVLTVLGVVVLDFSADATEGPIRAYLLDVVDSEEQDMALN 146 Query: 233 IHALLAGLGGGFGYVVGGIHWDKTGFGRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERP 292 IHA AGLGG GYV+GG+ W +T G Q +V++ F A+ +V+ L L SI E Sbjct: 147 IHAFSAGLGGAIGYVLGGLDWTQTFLGSWFRTQNQVLFFFAAIIFTVSVALHLFSIDEEQ 206 Query: 293 LRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLT---PKYG 349 P E+ A E G D H F + L P Sbjct: 207 YSPQQERSA----------------EEPGALDGGEPHGVPAFPDEVQSEHELALDYPDVD 250 Query: 350 SFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPD 409 S+ S + + A + I+ SY A P S + PR Sbjct: 251 IMRSKSDSALHVPDTALDLEPELLFLHDIEPSIFHDASYPATPRSTSQELAKTKLPRLAT 310 Query: 410 GF---YRQDRGLLEGR---------EGALTSGCDGDILRVGSLDTSKPRSSGILKRPQTL 457 ++D LL+ G+ T G RV DT +S ++R + Sbjct: 311 FLKEAAKEDETLLDNHLNEAKVPNGSGSPTKDALGGYTRV---DTKPSATSSSMRRRRHA 367 Query: 458 AIPDAA------GGGGPETSRRRNVTFSQQVANILLNGVKYESELTGSSERAEQ------ 505 A+ G G R R A +L+ + S+L +R Q Sbjct: 368 FRRQASSTFSYYGKLGSHCYRYRRAN-----AVVLIKPSRSMSDLYDMQKRQRQHRHRNQ 422 Query: 506 -----------------PLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFM 548 +V L ++ MP+ L LC+ H L W S +FYTDFM Sbjct: 423 SGATTSSGDTESEEGEGETTVRLLWLSMLKMPRELMRLCLCHLLTWFSVIAEAVFYTDFM 482 Query: 549 GEVVFQGDPKAPHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEK-LEEF-LSVRTL 606 G+V+F+GDPKAP S A+Q YN+GV MGCWG+ IYA + A SA+L+K L+ + LSVR + Sbjct: 483 GQVIFEGDPKAPSNSTAWQAYNAGVKMGCWGLVIYAATGAICSALLQKYLDNYDLSVRVI 542 Query: 607 YFIAYLAFGLGTGLATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSA 666 Y + L F +GT + + N+YV + T GI+ ++ PY+LL Y+ K++ S Sbjct: 543 YVLGTLGFSVGTAVMAMFPNVYVAMVTISTMGIVSMSISYCPYALLGQYHDIKQYIHHSP 602 Query: 667 DGTRRGMGVDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLF 726 ++RG G+D ++LSCQ +++QILV+ LG + AVG+ + +S+ SFLG L ++ Sbjct: 603 GNSKRGFGIDCAILSCQVYISQILVASALGGVVDAVGTVRVIPMVASVGSFLGFLTATFL 662 Query: 727 VIYEIPPSDAADEE 740 VIY +A +E+ Sbjct: 663 VIYPNVSEEAKEEQ 676 >gi|61635915 membrane-associated transporter protein isoform a [Homo sapiens] Length = 530 Score = 217 bits (552), Expect = 4e-56 Identities = 111/238 (46%), Positives = 151/238 (63%), Gaps = 6/238 (2%) Query: 80 PQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPL 139 P+R L+ + +FG EF YA+E AYVTPVLL +GLP LYS+VWF+SPILGFLLQP+ Sbjct: 28 PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPV 87 Query: 140 LGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIAL-ADVTGNHKWGLLLTVC 198 +G+ SD C SR+GRRRP+IL L + L+G++L LNG + AL A+ W + +T+ Sbjct: 88 VGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMI 147 Query: 199 GVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTGF 258 GVVL DF+AD D P AY+ DVCS D+++GL+ HAL G GG GY++G I W Sbjct: 148 GVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLEL 207 Query: 259 GRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPV 316 GR LG + +V++ F+A+ L++ + L SI E PL A P P PP+ Sbjct: 208 GRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPL-----TEVAKGIPPQQTPQDPPL 260 Score = 183 bits (465), Expect = 4e-46 Identities = 89/235 (37%), Positives = 142/235 (60%), Gaps = 5/235 (2%) Query: 500 SERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKA 559 +E+ + +++ L + NMP R LC++H +GW +F +LF+TDFMG++V++GDP + Sbjct: 294 AEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYS 353 Query: 560 PHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTG 619 H S + Y GV +GCWG CI + ++ YS + L ++ ++ LYF YL FGLGTG Sbjct: 354 AHNSTEFLIYERGVEVGCWGFCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTG 413 Query: 620 LATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYY-----QSKKFAGSSADGTRRGMG 674 L N+Y L LC +G++ STL T+P++L+ +Y+ + ++ G D + RG G Sbjct: 414 FIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEEKERQQAPGGDPDNSVRGKG 473 Query: 675 VDISLLSCQYFLAQILVSLVLGPLTSAVGSANGVMYFSSLVSFLGCLYSSLFVIY 729 +D + L+C LAQILV LG L + G+ V+ +S V+ +GC + +LFV Y Sbjct: 474 MDCATLTCMVQLAQILVGGGLGFLVNTAGTVVVVVITASAVALIGCCFVALFVRY 528 >gi|61636000 membrane-associated transporter protein isoform b [Homo sapiens] Length = 460 Score = 217 bits (552), Expect = 4e-56 Identities = 111/238 (46%), Positives = 151/238 (63%), Gaps = 6/238 (2%) Query: 80 PQRSFRELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPL 139 P+R L+ + +FG EF YA+E AYVTPVLL +GLP LYS+VWF+SPILGFLLQP+ Sbjct: 28 PKRPTSRLIMHSMAMFGREFCYAVEAAYVTPVLLSVGLPSSLYSIVWFLSPILGFLLQPV 87 Query: 140 LGAWSDRCTSRFGRRRPFILVLAIGALLGLSLLLNGRDIGIAL-ADVTGNHKWGLLLTVC 198 +G+ SD C SR+GRRRP+IL L + L+G++L LNG + AL A+ W + +T+ Sbjct: 88 VGSASDHCRSRWGRRRPYILTLGVMMLVGMALYLNGATVVAALIANPRRKLVWAISVTMI 147 Query: 199 GVVLMDFSADSADNPSHAYMMDVCSPADQDRGLNIHALLAGLGGGFGYVVGGIHWDKTGF 258 GVVL DF+AD D P AY+ DVCS D+++GL+ HAL G GG GY++G I W Sbjct: 148 GVVLFDFAADFIDGPIKAYLFDVCSHQDKEKGLHYHALFTGFGGALGYLLGAIDWAHLEL 207 Query: 259 GRALGGQLRVIYLFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPV 316 GR LG + +V++ F+A+ L++ + L SI E PL A P P PP+ Sbjct: 208 GRLLGTEFQVMFFFSALVLTLCFTVHLCSISEAPL-----TEVAKGIPPQQTPQDPPL 260 Score = 145 bits (366), Expect = 1e-34 Identities = 62/161 (38%), Positives = 103/161 (63%) Query: 500 SERAEQPLSVGRLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKA 559 +E+ + +++ L + NMP R LC++H +GW +F +LF+TDFMG++V++GDP + Sbjct: 294 AEQTRRAMTLKSLLRALVNMPPHYRYLCISHLIGWTAFLSNMLFFTDFMGQIVYRGDPYS 353 Query: 560 PHTSEAYQKYNSGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTG 619 H S + Y GV +GCWG CI + ++ YS + L ++ ++ LYF YL FGLGTG Sbjct: 354 AHNSTEFLIYERGVEVGCWGFCINSVFSSLYSYFQKVLVSYIGLKGLYFTGYLLFGLGTG 413 Query: 620 LATLSRNLYVVLSLCITYGILFSTLCTLPYSLLCDYYQSKK 660 L N+Y L LC +G++ STL T+P++L+ +Y++ ++ Sbjct: 414 FIGLFPNVYSTLVLCSLFGVMSSTLYTVPFNLITEYHREEE 454 >gi|14916437 prostein [Homo sapiens] Length = 553 Score = 111 bits (277), Expect = 3e-24 Identities = 75/226 (33%), Positives = 113/226 (50%), Gaps = 8/226 (3%) Query: 86 ELLFNGCILFGIEFSYAMETAYVTPVLLQMGLPDQLYSLVWFISPILGFLLQPLLGAWSD 145 +LL + FG+E A YV P+LL++G+ ++ ++V I P+LG + PLLG+ SD Sbjct: 17 QLLLVNLLTFGLEVCLAAGITYVPPLLLEVGVEEKFMTMVLGIGPVLGLVCVPLLGSASD 76 Query: 146 RCTSRFGRRRPFILVLAIGALLGLSLLLN-GRDIGIALADVTGNHKWGLLLTVCGVVLMD 204 R+GRRRPFI L++G LL L L+ G G+ D L L + GV L+D Sbjct: 77 HWRGRYGRRRPFIWALSLGILLSLFLIPRAGWLAGLLCPD---PRPLELALLILGVGLLD 133 Query: 205 FSADSADNPSHAYMMDVCSPADQDR-GLNIHALLAGLGGGFGYVVGGIHWDKTGFGRALG 263 F P A + D+ D R +++A + LGG GY++ I WD + LG Sbjct: 134 FCGQVCFTPLEALLSDLFRDPDHCRQAYSVYAFMISLGGCLGYLLPAIDWDTSALAPYLG 193 Query: 264 GQLRVIY-LFTAVTLSVTTVLTLVSIPERPLRPPSEKRAAMKSPSL 308 Q ++ L T + L T V + + E P+E + +PSL Sbjct: 194 TQEECLFGLLTLIFL--TCVAATLLVAEEAALGPTEPAEGLSAPSL 237 Score = 99.4 bits (246), Expect = 1e-20 Identities = 55/171 (32%), Positives = 87/171 (50%) Query: 511 RLCSTICNMPKALRTLCVNHFLGWLSFEGMLLFYTDFMGEVVFQGDPKAPHTSEAYQKYN 570 RL C MP+ LR L V W++ LFYTDF+GE ++QG P+A +EA + Y+ Sbjct: 259 RLHQLCCRMPRTLRRLFVAELCSWMALMTFTLFYTDFVGEGLYQGVPRAEPGTEARRHYD 318 Query: 571 SGVTMGCWGMCIYAFSAAFYSAILEKLEEFLSVRTLYFIAYLAFGLGTGLATLSRNLYVV 630 GV MG G+ + + +S ++++L + R +Y + AF + G LS ++ VV Sbjct: 319 EGVRMGSLGLFLQCAISLVFSLVMDRLVQRFGTRAVYLASVAAFPVAAGATCLSHSVAVV 378 Query: 631 LSLCITYGILFSTLCTLPYSLLCDYYQSKKFAGSSADGTRRGMGVDISLLS 681 + G FS L LPY+L Y++ K+ G G + SL++ Sbjct: 379 TASAALTGFTFSALQILPYTLASLYHREKQVFLPKYRGDTGGASSEDSLMT 429 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 43.5 bits (101), Expect = 7e-04 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 282 VLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF--SSPIS 339 VL ++ P P PP +A++ P P PP PP LP GP P N P Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366 Query: 340 PPSPLTPKYGSFISRDSS----LTGIS 362 PP+P P G F++ S LTG++ Sbjct: 367 PPAPPLPASGFFLASMSEDNRPLTGLA 393 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 43.5 bits (101), Expect = 7e-04 Identities = 30/87 (34%), Positives = 40/87 (45%), Gaps = 6/87 (6%) Query: 282 VLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF--SSPIS 339 VL ++ P P PP +A++ P P PP PP LP GP P N P Sbjct: 307 VLGPLAPPPPPPLPPGPAQASVALPPPPGPPPPPPLPSTGPPPPPPPPPLPNQVPPPPPP 366 Query: 340 PPSPLTPKYGSFISRDSS----LTGIS 362 PP+P P G F++ S LTG++ Sbjct: 367 PPAPPLPASGFFLASMSEDNRPLTGLA 393 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 39.3 bits (90), Expect = 0.013 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSS---------PISPPSPLT 345 PPS+ ++ +P L +PPSPP P P + P ++ P +PP+ T Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525 Query: 346 PKYGSFISRDSSLTGISEFASS 367 P + S +S G + F+ S Sbjct: 526 PPLQALPSPPASFPGQAPFSPS 547 Score = 36.6 bits (83), Expect = 0.087 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLP----PSPPVLPEEGPGDSLPSHTA-TNFSSPI 338 +L ++P P PPS+ ++ SP+L PSPP+ P P P A +P Sbjct: 350 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409 Query: 339 SPPS--PLTP 346 SPP+ PL+P Sbjct: 410 SPPASPPLSP 419 Score = 35.4 bits (80), Expect = 0.19 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 14/75 (18%) Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATN---------- 333 L S P PL PP + A+ P L PPSPP P P + PS A N Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPNALAVHLLQAP 439 Query: 334 FSSPISPP--SPLTP 346 FS P SPP +P +P Sbjct: 440 FSPPPSPPVQAPFSP 454 Score = 34.7 bits (78), Expect = 0.33 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336 S+P PL PP + + +P L +PPSPP P GP S+ T + Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 608 Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367 P PP P + D L G S A+S Sbjct: 609 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 637 Score = 32.7 bits (73), Expect = 1.3 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344 L + P + +PP + A+ +P L PSPP PG + S +A+ SP++ P P Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQ 561 Query: 345 TP 346 P Sbjct: 562 AP 563 Score = 32.0 bits (71), Expect = 2.2 Identities = 24/55 (43%), Positives = 25/55 (45%), Gaps = 6/55 (10%) Query: 292 PLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHT--ATNFSSPISPPSPL 344 PL PPS PSL PSPP P SL S T AT+ P P SPL Sbjct: 339 PLAPPSPSAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 39.3 bits (90), Expect = 0.013 Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 9/82 (10%) Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSS---------PISPPSPLT 345 PPS+ ++ +P L +PPSPP P P + P ++ P +PP+ T Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486 Query: 346 PKYGSFISRDSSLTGISEFASS 367 P + S +S G + F+ S Sbjct: 487 PPLQALPSPPASFPGQAPFSPS 508 Score = 36.6 bits (83), Expect = 0.087 Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 7/70 (10%) Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLP----PSPPVLPEEGPGDSLPSHTA-TNFSSPI 338 +L ++P P PPS+ ++ SP+L PSPP+ P P P A +P Sbjct: 311 SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 Query: 339 SPPS--PLTP 346 SPP+ PL+P Sbjct: 371 SPPASPPLSP 380 Score = 35.4 bits (80), Expect = 0.19 Identities = 29/75 (38%), Positives = 34/75 (45%), Gaps = 14/75 (18%) Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATN---------- 333 L S P PL PP + A+ P L PPSPP P P + PS A N Sbjct: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATPSPQAPNALAVHLLQAP 400 Query: 334 FSSPISPP--SPLTP 346 FS P SPP +P +P Sbjct: 401 FSPPPSPPVQAPFSP 415 Score = 34.7 bits (78), Expect = 0.33 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336 S+P PL PP + + +P L +PPSPP P GP S+ T + Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569 Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367 P PP P + D L G S A+S Sbjct: 570 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 598 Score = 32.7 bits (73), Expect = 1.3 Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 3/62 (4%) Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344 L + P + +PP + A+ +P L PSPP PG + S +A+ SP++ P P Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQ 522 Query: 345 TP 346 P Sbjct: 523 AP 524 Score = 30.0 bits (66), Expect = 8.2 Identities = 24/57 (42%), Positives = 25/57 (43%), Gaps = 4/57 (7%) Query: 292 PLRPPSEKRAAMKS--PSLPLPPSPPVLPEEGPGDSLPSHT--ATNFSSPISPPSPL 344 PL PS S PSL PSPP P SL S T AT+ P P SPL Sbjct: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350 >gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo sapiens] Length = 468 Score = 39.3 bits (90), Expect = 0.013 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 3/61 (4%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348 P RP P +E + P+LP+P +P P P P + P+ PP P P Y Sbjct: 198 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA---PGRKGSIQDRPLPPPPPRLPGY 254 Query: 349 G 349 G Sbjct: 255 G 255 >gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sapiens] Length = 561 Score = 39.3 bits (90), Expect = 0.013 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 3/61 (4%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348 P RP P +E + P+LP+P +P P P P + P+ PP P P Y Sbjct: 291 PHRPRLPSAESLSRRPLPALPVPEAPSPSPVPSPA---PGRKGSIQDRPLPPPPPRLPGY 347 Query: 349 G 349 G Sbjct: 348 G 348 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 37.7 bits (86), Expect = 0.039 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 3/70 (4%) Query: 276 TLSVTTVLTLVSIPE-RPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNF 334 T +V V+T + P P PP++K+ A P+ +PPSPP P P +LP + Sbjct: 791 TKTVAPVVTQAAPPTPTPPVPPAKKQPAF--PASYIPPSPPTPPVPVPPPTLPKQQSFCA 848 Query: 335 SSPISPPSPL 344 P SP SP+ Sbjct: 849 KPPPSPLSPV 858 Score = 30.4 bits (67), Expect = 6.3 Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 13/71 (18%) Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGD-------SLPSHTATNFSSPI- 338 S P PL+ + +P P PP PP +P P ++P+ T+T +P+ Sbjct: 741 SAPPPPLKIHQVQHITQVAP--PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVV 798 Query: 339 ---SPPSPLTP 346 +PP+P P Sbjct: 799 TQAAPPTPTPP 809 Score = 30.4 bits (67), Expect = 6.3 Identities = 23/75 (30%), Positives = 27/75 (36%), Gaps = 4/75 (5%) Query: 286 VSIPERPLRPPSEKRAAMKSPSLPLP-PSPPVLPEEGP---GDSLPSHTATNFSSPISPP 341 V P+ P PP P P+P P PP P P P + SSP Sbjct: 911 VPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKK 970 Query: 342 SPLTPKYGSFISRDS 356 P TP+ S I S Sbjct: 971 PPPTPQRNSSIKSSS 985 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 37.0 bits (84), Expect = 0.067 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 2/51 (3%) Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSP--ISPPSP 343 PPS+ ++ +P L +PPSPP P P + P ++P PPSP Sbjct: 691 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741 Score = 35.8 bits (81), Expect = 0.15 Identities = 25/59 (42%), Positives = 29/59 (49%), Gaps = 6/59 (10%) Query: 291 RPLRPPSEKRAAMKSPSLPLPPSPPV---LPEEGPGDSLPSHTATNFSSPISPPSPLTP 346 RP+ PP AA P+ LPPSPP+ LP P S P T S P +PPS P Sbjct: 315 RPVPPPDN--AATPLPAT-LPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370 Score = 35.0 bits (79), Expect = 0.25 Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 4/61 (6%) Query: 287 SIPERPL-RPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLT 345 S+P PL +PP + A+ +P L PSPP PG + S +A+ SP++ P P Sbjct: 775 SLPMSPLAKPPPQAPPALATPPLQALPSPPA---SFPGQAPFSPSASLPMSPLATPPPQA 831 Query: 346 P 346 P Sbjct: 832 P 832 Score = 34.7 bits (78), Expect = 0.33 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 10/63 (15%) Query: 284 TLVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPI--SPP 341 +L ++P P PPS+ +M +P + PPS +P P + +SP +PP Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP--------PIQVPHSLTSPSLQAPP 404 Query: 342 SPL 344 SPL Sbjct: 405 SPL 407 Score = 34.7 bits (78), Expect = 0.33 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 12/91 (13%) Query: 287 SIPERPLR-PPSEKRAAMKSPSLPLPPSPPVL---------PEEGPGDSLPSHTATNFSS 336 S+P PL PP + + +P L +PPSPP P GP S+ T + Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877 Query: 337 PISPPSPLTPKYGSFISRDSSLTGISEFASS 367 P PP P + D L G S A+S Sbjct: 878 PGPPPPPSRSPSSTLSGPD--LAGHSSSATS 906 Score = 33.9 bits (76), Expect = 0.57 Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 295 PPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSP--ISPPSP 343 PP + + +P L +PPSPP P P + P ++P PPSP Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSP 772 Score = 33.5 bits (75), Expect = 0.74 Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 6/64 (9%) Query: 289 PERP---LRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTA-TNFSSPISPPS-- 342 PE P PP + A+ SP L PSPP+ P P P A +P SPP+ Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640 Query: 343 PLTP 346 PL+P Sbjct: 641 PLSP 644 Score = 32.0 bits (71), Expect = 2.2 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 12/74 (16%) Query: 285 LVSIPERPLR-PPSEKRAAMKSPSLPLPPSPP----VLPEEGPGDSLPSHTATN-----F 334 L S P PL PP + + P L PPSPP + P P P+ A + F Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665 Query: 335 SSPISPP--SPLTP 346 S P SPP +P +P Sbjct: 666 SPPPSPPVQAPFSP 679 Score = 32.0 bits (71), Expect = 2.2 Identities = 23/79 (29%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348 P P PP A PL +PP+ P SLP P +PP+ TP Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK-PPPQAPPALATPPL 797 Query: 349 GSFISRDSSLTGISEFASS 367 + S +S G + F+ S Sbjct: 798 QALPSPPASFPGQAPFSPS 816 >gi|157743257 POU domain, class 6, transcription factor 2 [Homo sapiens] Length = 691 Score = 37.0 bits (84), Expect = 0.067 Identities = 49/213 (23%), Positives = 78/213 (36%), Gaps = 27/213 (12%) Query: 313 SPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKYGSFISR-DSSLTGISEFASS--FG 369 SPP P + PG LP SP++PP+PL S+ ++ +S ASS FG Sbjct: 271 SPPQKPSQSPGHGLP--------SPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQAFG 322 Query: 370 TA--NIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAPDGFYRQ--DRGLLEGREGA 425 A ++ V T + +P P S G Q LL +G Sbjct: 323 NALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQ 382 Query: 426 LTSGCDGD----ILRVGSLDTSKPRSSGILKRPQTLAIPDAAGGGGPETSRRRNVTFSQQ 481 + + G+ ++ + S + L +P ++ AA G + SQ Sbjct: 383 IIATVIGNQILPVINTQGITLSPIKPGQQLHQPSQTSVGQAASQGNLLHLAHSQASMSQS 442 Query: 482 VANILLNGVKYESELTGSSERAEQPLSVGRLCS 514 ++ + SS + LSVG+L S Sbjct: 443 PVR--------QASSSSSSSSSSSALSVGQLVS 467 >gi|19718731 bromodomain-containing protein 4 isoform long [Homo sapiens] Length = 1362 Score = 36.6 bits (83), Expect = 0.087 Identities = 23/68 (33%), Positives = 33/68 (48%), Gaps = 8/68 (11%) Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPP--SPPVL---PEEGPGDSLPSHTATNF---SSPI 338 ++P +P RPP+ A ++P LP PP PP + EE P L S + + Sbjct: 879 ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938 Query: 339 SPPSPLTP 346 PP+PL P Sbjct: 939 QPPTPLLP 946 >gi|151301053 RNA binding motif protein 33 [Homo sapiens] Length = 1170 Score = 36.6 bits (83), Expect = 0.087 Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 17/67 (25%) Query: 290 ERPLRPP------------SEKRAAMKSPSLPLPPSPPVLPEEGPGDS-LPSHTATNFSS 336 ERP+RP S+ +A P +P P P LP GPG LP+HT N Sbjct: 525 ERPVRPALQPPGPVGILHFSQPGSATTRPFIP--PRQPFLP--GPGQPFLPTHTQPNLQG 580 Query: 337 PISPPSP 343 P+ PP P Sbjct: 581 PLHPPLP 587 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 36.6 bits (83), Expect = 0.087 Identities = 39/127 (30%), Positives = 49/127 (38%), Gaps = 13/127 (10%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSH-TATNFSSPISPPSPLTPK 347 P RP PP + + SP P PP PP G +LP ++ +P PP PL P Sbjct: 570 PARPTMPPPQVSGSRSSP--PAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPP-PLPPT 626 Query: 348 YGSFISRDSSLTGISEFASSFGTA--------NIDSVLIDCFTGGHDSYLAIPGSVPRPP 399 R S + S +S G A N V + T + AI G VP PP Sbjct: 627 PPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATAEGGAPEAISG-VPTPP 685 Query: 400 ISVSFPR 406 PR Sbjct: 686 AIPPQPR 692 >gi|116235472 SH3-domain GRB2-like (endophilin) interacting protein 1 [Homo sapiens] Length = 828 Score = 36.2 bits (82), Expect = 0.11 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 10/78 (12%) Query: 287 SIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPI--SPPSPL 344 S P RP P R+ P P PPS P LP PG + FS PI S P P+ Sbjct: 441 SSPARPATPLVPCRSTTPPPPPPRPPSRPKLPPGKPG---VGDVSRPFSPPIHSSSPPPI 497 Query: 345 TPKYGSFISRDSSLTGIS 362 P ++R S + IS Sbjct: 498 AP-----LARAESTSSIS 510 Score = 33.1 bits (74), Expect = 0.97 Identities = 19/54 (35%), Positives = 24/54 (44%), Gaps = 4/54 (7%) Query: 297 SEKRAAMKSPSLPLPPSPP----VLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346 S K + + P PP PP V+ GPG T + SSP P +PL P Sbjct: 399 SPKDFGLGQRATPPPPPPPTYRTVVSSPGPGSGPGPGTTSGASSPARPATPLVP 452 >gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sapiens] Length = 505 Score = 35.8 bits (81), Expect = 0.15 Identities = 19/57 (33%), Positives = 24/57 (42%), Gaps = 2/57 (3%) Query: 292 PLRPPSEKRAAMKSP--SLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346 P PPS A+ P + PP PP LP P P + P++PP P P Sbjct: 323 PPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPP 379 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 35.8 bits (81), Expect = 0.15 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 11/81 (13%) Query: 289 PERPLRPPSEKRAA--MKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346 P P PP + M PS+P PP PPV+P++ P ++ NF PP P Sbjct: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF-----PP----P 180 Query: 347 KYGSFISRDSSLTGISEFASS 367 + SF + SS + +SS Sbjct: 181 SFNSFQNNPSSFLPSANNSSS 201 >gi|155030234 ribonuclease III, nuclear isoform 1 [Homo sapiens] Length = 1374 Score = 35.8 bits (81), Expect = 0.15 Identities = 26/81 (32%), Positives = 37/81 (45%), Gaps = 11/81 (13%) Query: 289 PERPLRPPSEKRAA--MKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTP 346 P P PP + M PS+P PP PPV+P++ P ++ NF PP P Sbjct: 130 PPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNF-----PP----P 180 Query: 347 KYGSFISRDSSLTGISEFASS 367 + SF + SS + +SS Sbjct: 181 SFNSFQNNPSSFLPSANNSSS 201 >gi|56676337 transmembrane protein 28 [Homo sapiens] Length = 472 Score = 35.8 bits (81), Expect = 0.15 Identities = 51/190 (26%), Positives = 69/190 (36%), Gaps = 39/190 (20%) Query: 293 LRPP----SEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPKY 348 +RPP E++ LPLPP PP P PG P ++ ++P + P+ Sbjct: 78 MRPPWGAGRERQPVPPRAVLPLPPPPPGEPSAPPGTCGPRYSNLTKAAPAAGSRPVCGGV 137 Query: 349 GSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVSFPRAP 408 D++ T + F P RPP S+S RAP Sbjct: 138 PEPTGLDAACTKLQSLQRLFEPTT-------------------PAPPLRPPDSLS--RAP 176 Query: 409 DGFYRQDRGLLEGREGALT-SGCD----GDIL----RVGSLDTSKPRSSGILKRPQTLAI 459 F + LL+G T S CD D+L R SLD S G L LA+ Sbjct: 177 AEFPSAKKNLLKGHFRNFTLSFCDTYTVWDLLLGMDRPDSLDCSLDTLMGDL-----LAV 231 Query: 460 PDAAGGGGPE 469 + G G E Sbjct: 232 VASPGSGAWE 241 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 35.4 bits (80), Expect = 0.19 Identities = 24/75 (32%), Positives = 33/75 (44%), Gaps = 3/75 (4%) Query: 273 TAVTLSVTTVLTLVSIPERPLRPPSEK-RAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTA 331 TA LS T TL P+ L PP+ + K+P++P P P P S P+ T Sbjct: 1530 TATLLSKKTPATLA--PKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTP 1587 Query: 332 TNFSSPISPPSPLTP 346 + + SP L P Sbjct: 1588 STYKGAPSPKELLIP 1602 Score = 32.3 bits (72), Expect = 1.6 Identities = 26/81 (32%), Positives = 38/81 (46%), Gaps = 20/81 (24%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSPPVL----PEEGPGDSLPSHTATNFSSPISP---- 340 P+ L PP A+ SPS P+PP + PE+GP P T T S P++P Sbjct: 1596 PKELLIPP-----AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT--SPPVTPSSLK 1648 Query: 341 -----PSPLTPKYGSFISRDS 356 P+ +T K G+ + + S Sbjct: 1649 DSPTSPASVTCKMGATVPQAS 1669 Score = 31.2 bits (69), Expect = 3.7 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 8/66 (12%) Query: 289 PERPLRPPSEKRAAM-----KSPSLPLPPSPPVLPEEGPGD--SLPSHTATNFSSPISPP 341 P P PP+ K+ A K+P+ P P P LP P +P+ T ++ PI+P Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA-TPSSRRDPIAPT 1530 Query: 342 SPLTPK 347 + L K Sbjct: 1531 ATLLSK 1536 >gi|33356148 formin-like 1 [Homo sapiens] Length = 1100 Score = 35.4 bits (80), Expect = 0.19 Identities = 20/62 (32%), Positives = 23/62 (37%) Query: 285 LVSIPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPL 344 L +P PPS A P P PP P LP + P P P+ PP P Sbjct: 548 LPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPP 607 Query: 345 TP 346 P Sbjct: 608 PP 609 >gi|4885407 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 [Homo sapiens] Length = 1203 Score = 35.0 bits (79), Expect = 0.25 Identities = 54/195 (27%), Positives = 64/195 (32%), Gaps = 32/195 (16%) Query: 286 VSIPERPLRPPSEKRAAMKSP----------SLPLPPSPPVLPEEGPGDSLPSHTATNFS 335 + +PE L PP R+ SP SL L P PE P P S Sbjct: 952 LGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPLSTPETPPRQPEPPSLVAGAS 1011 Query: 336 SPISPPSPLTPKYGSFISRDSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSV 395 SP TP+ G+S S G +G H S L P S Sbjct: 1012 GGASPVG-FTPR-----------GGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASS 1059 Query: 396 PRP---PISVSFPRAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDTSKPRSSGILK 452 P P P P G QD L+ + AL DG +L + P SSG Sbjct: 1060 PPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQ--DG----AQTLRRASPHSSGESM 1113 Query: 453 RPQTLAIPDAAGGGG 467 L P A GG G Sbjct: 1114 AAFPL-FPRAGGGSG 1127 >gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] Length = 733 Score = 35.0 bits (79), Expect = 0.25 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 19/157 (12%) Query: 288 IPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPK 347 +P RP PPS AA K P L LP PP+ ++ + PS S P P P Sbjct: 264 LPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPD 323 Query: 348 YGSFISR-DSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVS-FP 405 S + R G+ + G S C G D+ ++ PG PP+ ++ P Sbjct: 324 GPSLLYRWMKHEPGLGSYGDELGRER-GSPSERCEERGGDAAVS-PGG---PPLGLAPPP 378 Query: 406 RAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDT 442 R P G L+G GA G DGD + S +T Sbjct: 379 RYP--------GSLDG-PGA---GGDGDDYKSSSEET 403 >gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] Length = 714 Score = 35.0 bits (79), Expect = 0.25 Identities = 47/157 (29%), Positives = 64/157 (40%), Gaps = 19/157 (12%) Query: 288 IPERPLRPPSEKRAAMKSPSLPLPPSPPVLPEEGPGDSLPSHTATNFSSPISPPSPLTPK 347 +P RP PPS AA K P L LP PP+ ++ + PS S P P P Sbjct: 245 LPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGSPGPEPPGRPD 304 Query: 348 YGSFISR-DSSLTGISEFASSFGTANIDSVLIDCFTGGHDSYLAIPGSVPRPPISVS-FP 405 S + R G+ + G S C G D+ ++ PG PP+ ++ P Sbjct: 305 GPSLLYRWMKHEPGLGSYGDELGRER-GSPSERCEERGGDAAVS-PGG---PPLGLAPPP 359 Query: 406 RAPDGFYRQDRGLLEGREGALTSGCDGDILRVGSLDT 442 R P G L+G GA G DGD + S +T Sbjct: 360 RYP--------GSLDG-PGA---GGDGDDYKSSSEET 384 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 34.7 bits (78), Expect = 0.33 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334 T T+ S P P P P+ ++A +P P P P+P E P + T Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292 Query: 335 SSPISP--PSPLTPK 347 S+P +P P+P TPK Sbjct: 293 SAPTTPKEPAPTTPK 307 Score = 34.3 bits (77), Expect = 0.43 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340 PE P P + K AA +P P P +P P P+E P + P TA +P Sbjct: 527 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 584 Query: 341 -PSPLTPK 347 P+P TPK Sbjct: 585 EPAPTTPK 592 Score = 33.1 bits (74), Expect = 0.97 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332 TT + + P+ P P + K A +P P P +P P P+E P + P T T Sbjct: 406 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 463 Query: 333 NFSSPISP--PSPLTPK 347 +P +P P+P TPK Sbjct: 464 KKPAPTTPKEPAPTTPK 480 Score = 30.4 bits (67), Expect = 6.3 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343 P P P P+ K A +P P P +P P P+E P + P A + PSP Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 382 Query: 344 LTPK 347 TPK Sbjct: 383 TTPK 386 Score = 30.0 bits (66), Expect = 8.2 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342 + L P + ++ A +P P P +P P PEE + P+ T ++P +P P+ Sbjct: 488 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 547 Query: 343 PLTPK 347 P TPK Sbjct: 548 PTTPK 552 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 34.7 bits (78), Expect = 0.33 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334 T T+ S P P P P+ ++A +P P P P+P E P + T Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333 Query: 335 SSPISP--PSPLTPK 347 S+P +P P+P TPK Sbjct: 334 SAPTTPKEPAPTTPK 348 Score = 34.3 bits (77), Expect = 0.43 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340 PE P P + K AA +P P P +P P P+E P + P TA +P Sbjct: 568 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 625 Query: 341 -PSPLTPK 347 P+P TPK Sbjct: 626 EPAPTTPK 633 Score = 33.1 bits (74), Expect = 0.97 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332 TT + + P+ P P + K A +P P P +P P P+E P + P T T Sbjct: 447 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 504 Query: 333 NFSSPISP--PSPLTPK 347 +P +P P+P TPK Sbjct: 505 KKPAPTTPKEPAPTTPK 521 Score = 30.4 bits (67), Expect = 6.3 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343 P P P P+ K A +P P P +P P P+E P + P A + PSP Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 423 Query: 344 LTPK 347 TPK Sbjct: 424 TTPK 427 Score = 30.0 bits (66), Expect = 8.2 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342 + L P + ++ A +P P P +P P PEE + P+ T ++P +P P+ Sbjct: 529 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 588 Query: 343 PLTPK 347 P TPK Sbjct: 589 PTTPK 593 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 34.7 bits (78), Expect = 0.33 Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 8/75 (10%) Query: 281 TVLTLVSIPERPLRP-PSEKRAAMKSPSLPLP-----PSPPVLPEEGPGDSLPSHTATNF 334 T T+ S P P P P+ ++A +P P P P+P E P + T Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385 Query: 335 SSPISP--PSPLTPK 347 S+P +P P+P TPK Sbjct: 386 SAPTTPKEPAPTTPK 400 Score = 34.3 bits (77), Expect = 0.43 Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 11/68 (16%) Query: 289 PERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISP---- 340 PE P P + K AA +P P P +P P P+E P + P TA +P Sbjct: 620 PEEPA-PTTPKAAAPNTPKEPAPTTPKEPAPTTPKE-PAPTTPKETAPTTPKGTAPTTLK 677 Query: 341 -PSPLTPK 347 P+P TPK Sbjct: 678 EPAPTTPK 685 Score = 33.1 bits (74), Expect = 0.97 Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 11/77 (14%) Query: 280 TTVLTLVSIPERPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSH---TAT 332 TT + + P+ P P + K A +P P P +P P P+E P + P T T Sbjct: 499 TTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKE-PAPTTPKEPAPTTT 556 Query: 333 NFSSPISP--PSPLTPK 347 +P +P P+P TPK Sbjct: 557 KKPAPTTPKEPAPTTPK 573 Score = 30.4 bits (67), Expect = 6.3 Identities = 22/64 (34%), Positives = 28/64 (43%), Gaps = 9/64 (14%) Query: 289 PERPLRP-PSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSLPSHTATNFSSPISPPSP 343 P P P P+ K A +P P P +P P P+E P + P A + PSP Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-PAPTTPKEPAPTTTKE---PSP 475 Query: 344 LTPK 347 TPK Sbjct: 476 TTPK 479 Score = 30.0 bits (66), Expect = 8.2 Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 291 RPLRPPSEKRAAMKSPSLPLPPSP----PVLPEEGPGDSL--PSHTATNFSSPISP--PS 342 + L P + ++ A +P P P +P P PEE + P+ T ++P +P P+ Sbjct: 581 KKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPA 640 Query: 343 PLTPK 347 P TPK Sbjct: 641 PTTPK 645 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.139 0.431 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,275,770 Number of Sequences: 37866 Number of extensions: 1661191 Number of successful extensions: 13538 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 227 Number of HSP's that attempted gapping in prelim test: 11669 Number of HSP's gapped (non-prelim): 1937 length of query: 748 length of database: 18,247,518 effective HSP length: 110 effective length of query: 638 effective length of database: 14,082,258 effective search space: 8984480604 effective search space used: 8984480604 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.