Guide to the Human Genome
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Search of human proteins with 12232415

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12232415 hypothetical protein LOC64762 [Homo sapiens]
         (875 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|12232415 hypothetical protein LOC64762 [Homo sapiens]             1798   0.0  
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   4e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    49   3e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    48   3e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   47   8e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   47   8e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   47   8e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    47   8e-05
gi|239754668 PREDICTED: mucin 12 [Homo sapiens]                        45   2e-04
gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]    45   2e-04
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        45   2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        45   4e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         45   4e-04
gi|116284392 mucin 2 precursor [Homo sapiens]                          44   5e-04
gi|154090979 hypothetical protein LOC57481 [Homo sapiens]              44   7e-04
gi|91982772 mucin 17 [Homo sapiens]                                    43   0.001
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   0.001
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   0.001
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho...    43   0.001
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom...    43   0.001
gi|150170670 piccolo isoform 2 [Homo sapiens]                          43   0.001
gi|150378539 piccolo isoform 1 [Homo sapiens]                          43   0.001
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              43   0.001
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             43   0.001
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             42   0.002
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]         42   0.002
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ...    42   0.003
gi|66932999 testis-specific protein kinase 1 [Homo sapiens]            42   0.003
gi|54860079 nadrin isoform 1 [Homo sapiens]                            42   0.003
gi|54860105 nadrin isoform 2 [Homo sapiens]                            42   0.003

>gi|12232415 hypothetical protein LOC64762 [Homo sapiens]
          Length = 875

 Score = 1798 bits (4657), Expect = 0.0
 Identities = 875/875 (100%), Positives = 875/875 (100%)

Query: 1   MDPAPSLGCSLKDVKWSSVAVPLDLLVSTYRLPQIARLDNGECVEGLRENDYLLIHSCRQ 60
           MDPAPSLGCSLKDVKWSSVAVPLDLLVSTYRLPQIARLDNGECVEGLRENDYLLIHSCRQ
Sbjct: 1   MDPAPSLGCSLKDVKWSSVAVPLDLLVSTYRLPQIARLDNGECVEGLRENDYLLIHSCRQ 60

Query: 61  WTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERV 120
           WTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERV
Sbjct: 61  WTTITAHSLEEGHYVIGPKIEIPVHYAGQFKLLEQDRDIKEPVQYFNSVEEVAKAFPERV 120

Query: 121 YVMEDITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKK 180
           YVMEDITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKK
Sbjct: 121 YVMEDITFNVKVASGECNEDTEVYNITLCTGDELTLMGQAEILYAKTFKEKSRLNTIFKK 180

Query: 181 IGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIV 240
           IGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIV
Sbjct: 181 IGKLNSISKLGKGKMPCLICMNHRTNESISLPFQCKGRFSTRSPLELQMQEGEHTIRNIV 240

Query: 241 EKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLH 300
           EKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLH
Sbjct: 241 EKTRLPVNVTVPSPPPRNPYDLHFIREGHRYKFVNIQTKTVVVCCVLRNNKILPMHFPLH 300

Query: 301 LTVPKFSLPEHLVKGESWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEECKSPKKG 360
           LTVPKFSLPEHLVKGESWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEECKSPKKG
Sbjct: 301 LTVPKFSLPEHLVKGESWPETLVHHWLGICQEQFDIDEYSRAVRDVKTDWNEECKSPKKG 360

Query: 361 RCSGHNHVPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGDWAPFPHDI 420
           RCSGHNHVPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGDWAPFPHDI
Sbjct: 361 RCSGHNHVPNSLSYARDELTQSFHRLSVCVYGNNLHGNSEVNLHGCRDLGGDWAPFPHDI 420

Query: 421 LPYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQ 480
           LPYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQ
Sbjct: 421 LPYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQ 480

Query: 481 FRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSA 540
           FRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSA
Sbjct: 481 FRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSA 540

Query: 541 KPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRV 600
           KPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRV
Sbjct: 541 KPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRV 600

Query: 601 KTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTP 660
           KTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTP
Sbjct: 601 KTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTP 660

Query: 661 KRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTS 720
           KRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTS
Sbjct: 661 KRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTS 720

Query: 721 CPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASY 780
           CPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASY
Sbjct: 721 CPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASY 780

Query: 781 PFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVISFFVTEKIDGN 840
           PFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVISFFVTEKIDGN
Sbjct: 781 PFSSPLHLQLAPRSCGDGSPWQPPADLSGLSIEEVSKSLRFIGLSEDVISFFVTEKIDGN 840

Query: 841 LLVQLTEEILSEDFKLSKLQVKKIMQFINGWRPKI 875
           LLVQLTEEILSEDFKLSKLQVKKIMQFINGWRPKI
Sbjct: 841 LLVQLTEEILSEDFKLSKLQVKKIMQFINGWRPKI 875


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 84/330 (25%), Positives = 119/330 (36%), Gaps = 63/330 (19%)

Query: 490 ATSPLPIP---GTLGAAVKSSDTALPP-----PPVPPKSEAVREECRLLNAPPVP--PRS 539
           ++SPL  P   GT    V   D A  P     PP PP +        L  APP P  P S
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP------LPLAPPSPSAPPS 353

Query: 540 AKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNR 599
            + L + P+ PP    P+       +P        +   V  + T+PS   P S      
Sbjct: 354 LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQ--VPHSLTSPSLQAPPS-----P 406

Query: 600 VKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGT 659
           +   S+   +  GSP+ +A  S L+     + AS        L  PSR  S P    P  
Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS--------LTSPSRPASTPPDSPP-- 456

Query: 660 PKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQST 719
                 AP        L +  SP  +  SS ++  P  A        + SLA+   +   
Sbjct: 457 ----LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQA--------LSSLASHSPQAPL 504

Query: 720 SCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSAS 779
           S   +PP   +      + +T P  L     E  P    P L               +AS
Sbjct: 505 SSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ--------------TAS 550

Query: 780 YPFSSPLHLQLAPRSCGDGSPWQ-PPADLS 808
            P ++P HL+  P  C    P Q PP+ L+
Sbjct: 551 APLTTP-HLETPP--CPAPCPLQAPPSPLT 577



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 74/279 (26%), Positives = 100/279 (35%), Gaps = 25/279 (8%)

Query: 490 ATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTS--- 546
           A  PL +P +  A+   S +A PPP  PP   A       L  PP PP S  P+S S   
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-----LQVPPSPPAS-PPMSPSATP 753

Query: 547 -PSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSV 605
            P +PP    P  Q    PSP  S   S L          P+ +TP    P   + +   
Sbjct: 754 PPRVPPLLAAPPLQV--PPSPPASLPMSPLAK--PPPQAPPALATP----PLQALPSPPA 805

Query: 606 DL--KSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
               ++PF SPSA    S L+ P   +    +         P  S +    + P TP  +
Sbjct: 806 SFPGQAPF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTK--QSTSC 721
                      L   P  P +   SS++SG P  A +S  +T       G     +  + 
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATSTPEELRGYDSGPEGGAA 923

Query: 722 PALPPRAPKLVEEKVASETSPL-PLKIDGAEEDPKSGSP 759
            + PP A        A    P  PL   GA   P    P
Sbjct: 924 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 54/210 (25%), Positives = 73/210 (34%), Gaps = 22/210 (10%)

Query: 489 CATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS 548
           C     P P T       S  A PPP  PP         + L +PP+ P +  P    P 
Sbjct: 567 CPLQAPPSPLTTPPPETPSSIATPPPQAPP--ALASPPLQGLPSPPLSPLATPP----PQ 620

Query: 549 IPPRTVKPARQQTRSP--SPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVD 606
            PP    P  Q   SP  SP LS        + T +   P+ +  V           S  
Sbjct: 621 APPXLALPPLQAPPSPPASPPLS-------PLATPSPQAPN-ALAVHLLQAPFSPPPSPP 672

Query: 607 LKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPA 666
           +++PF  P++  VS   + P   S A  S       + PS   S P      TP    P 
Sbjct: 673 VQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPAS-PPMSPSATPPPQAPP 728

Query: 667 PFDFDGCELLASPTSPVTAEFSSSVSGCPK 696
           P       L   P+ P +   S S +  P+
Sbjct: 729 P--LAAPPLQVPPSPPASPPMSPSATPPPR 756



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 67/279 (24%), Positives = 89/279 (31%), Gaps = 44/279 (15%)

Query: 492 SPLPIPGTLGA---AVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS 548
           SPL  P        AV        PPP PP             +PPV P +  P    PS
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA----SPPVSPSATPPSQAPPS 698

Query: 549 I--PPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVD 606
           +  PP  V P+   +   SP+                T P ++ P    P          
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSA---------------TPPPQAPPPLAAP---------P 734

Query: 607 LKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPA 666
           L+ P   P++  +S   + P                + PS   S P       P +  PA
Sbjct: 735 LQVPPSPPASPPMSPSATPPPR---VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791

Query: 667 PFDFDGCELLASPTS--PVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPAL 724
                  + L SP +  P  A FS S S  P S   +        LAA + +   S PA 
Sbjct: 792 -LATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 725 P----PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
           P    PR P       +     L L +      P S SP
Sbjct: 850 PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 80/298 (26%), Positives = 101/298 (33%), Gaps = 72/298 (24%)

Query: 512 PPPPVPPKSEAVREECRLLNAPPVPPRSAKPLST-SPSIPPRTVKPARQQTRSPSPTLSY 570
           PP   PP+ +A         AP + P S+ PL+T SPS PP    P   QT  PSP    
Sbjct: 273 PPQVTPPRKDA---------APALGPLSSSPLATPSPSAPPSPSAPPSLQT-LPSPPA-- 320

Query: 571 YSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRL-SWPNHY 629
                        T PS++T                  +  GSP+ +A  S L S P   
Sbjct: 321 -------------TPPSQAT------------------TSLGSPTLQATHSFLPSPPLSP 349

Query: 630 SGASESQTRSDFLLDPSRSYSYPRQKTP----GTPKRNCP---------APFDFDGCELL 676
                 Q      L P ++   P    P     TP    P         APF        
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS------- 402

Query: 677 ASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKV 736
             P+ PV A FS   S  P S S +  S    SLAA   +   S PA PP +P       
Sbjct: 403 PPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461

Query: 737 ASETSPLPLKIDGAE--EDPKSGSPDLSEDQYFVKKGMQDIFSASYPFSSPLHLQLAP 792
           A    P PL     +  + P    P L+             F    PFS    L ++P
Sbjct: 462 A----PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 24/132 (18%)

Query: 490 ATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSI 549
           A  PL +P +  A+   S +A PPP  PP           L APP+  + AKP    P  
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPP----------LAAPPL--QLAKP---PPQA 480

Query: 550 PPRTVKPARQQTRSPS---PTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVD 606
           PP    P  Q   SP    P  + +S      ++   T P ++ PV   P  +V      
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP----- 535

Query: 607 LKSPFGSPSAEA 618
             SP  SP+ +A
Sbjct: 536 -PSPPASPTLQA 546



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 63/278 (22%), Positives = 93/278 (33%), Gaps = 28/278 (10%)

Query: 504 VKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSI-------------- 549
           + SS  A P P  PP   A      L + P  PP  A     SP++              
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349

Query: 550 ---PPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVD 606
              PP    PA       +P     S  L  + T +   P+ +  V           S  
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-ALAVHLLQAPFSPPPSPP 408

Query: 607 LKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPA 666
           +++PF  P++  VS   + P   S A  S       + PS   S P      TP    P 
Sbjct: 409 VQAPFSPPASPPVSPSATPP---SQAPPSLAAPPLQVPPSPPAS-PPMSPSATPPPQAPP 464

Query: 667 PFDFDGCELLASPTSPVTAEFSSSVSGCPK-SASYSLESTDVKSLAAGVTKQSTSCPALP 725
           P      +L   P     A  +  +   P   AS+  ++    S +  ++  +T  P  P
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524

Query: 726 P-RAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLS 762
           P  A  L++   +   SP       A   P +  PD S
Sbjct: 525 PVLAAPLLQVPPSPPASPTL----QAPRRPPTPGPDTS 558



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 66/275 (24%), Positives = 93/275 (33%), Gaps = 36/275 (13%)

Query: 493 PLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPR 552
           P+  P +  A+   S +A PP   PP   A       L  PP PP S  P+S S + PP+
Sbjct: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-----LQVPPSPPAS-PPMSPSATPPPQ 461

Query: 553 TVKPARQ---QTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDL-- 607
              P      Q   P P                   P+ +TP    P   + +       
Sbjct: 462 APPPLAAPPLQLAKPPP----------------QAPPALATP----PLQALPSPPASFPG 501

Query: 608 KSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAP 667
           ++PF SPSA    S L+ P   +    +         P  S +    + P TP  +    
Sbjct: 502 QAPF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 560

Query: 668 FDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTK--QSTSCPALP 725
                  L   P  P +   SS++SG P  A +S  +T       G     +  +  + P
Sbjct: 561 GPRLTLALAPGPPPPPSRSPSSTLSG-PDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619

Query: 726 PRAPKLVEEKVASETSPL-PLKIDGAEEDPKSGSP 759
           P A        A    P  PL   GA   P    P
Sbjct: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 16/80 (20%)

Query: 490 ATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSI 549
           A+ P   P +  A++  S  A PPP  PP   A      LL  PP PP S          
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP-----LLQVPPSPPAS---------- 541

Query: 550 PPRTVKPARQQTRSPSPTLS 569
            P    P R  T  P  ++S
Sbjct: 542 -PTLQAPRRPPTPGPDTSVS 560


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 79/371 (21%), Positives = 138/371 (37%), Gaps = 57/371 (15%)

Query: 425 DSGDSGSDYLFPEASEESAGIPGK-SELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRG 483
           DS DS       E  EE  G P K + +P + + L  GK + +    S SE++  D    
Sbjct: 86  DSEDSS------EEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEE 139

Query: 484 SVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPL 543
             + +           +   VK    A   PP   KS     +    ++   PP++ KP 
Sbjct: 140 DQKKQ----------PVQKGVKPQAKAAKAPPKKAKSSDSDSDS---SSEDEPPKNQKPK 186

Query: 544 STSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTD 603
            T  ++  +T  P +    +P       +S   +  + + ++ SE    +  P   V   
Sbjct: 187 ITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKK 246

Query: 604 SVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSY-------PRQKT 656
            V  K+P     A    +R S  +  S + E + +   + +    YS        P +K+
Sbjct: 247 QVVAKAPV---KAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKS 303

Query: 657 PGT--PKR------------NCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSL 702
            GT  PK+            +     D    E    PT  V ++ ++      K+A  S 
Sbjct: 304 LGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363

Query: 703 ESTD--------VKSLAAGVTKQSTSCPALPPRAPKL-----VEEKVASETSPLPLKIDG 749
           +S+D          S  AG TK S++ PA+  ++P +      ++ V      L  K D 
Sbjct: 364 DSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADS 423

Query: 750 AEEDPKSGSPD 760
           +  + +S S +
Sbjct: 424 SSSEEESSSSE 434


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 60/273 (21%), Positives = 96/273 (35%), Gaps = 18/273 (6%)

Query: 491 TSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIP 550
           T+    P T      ++  + P  P  P     +E        P P    KP  T+P  P
Sbjct: 391 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 450

Query: 551 PRTV--KPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLK 608
             T   +PA   T+ P+PT     +      T  +T P  +TP    P    K      +
Sbjct: 451 APTTPKEPAPTTTKKPAPTTPKEPAP----TTPKETAP--TTPKKLTPTTPEKLAPTTPE 504

Query: 609 SPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPF 668
            P  +   E   +    P   +    + T        + + + P++  P TPK   P   
Sbjct: 505 KPAPTTPEELAPTTPEEPTPTTPEEPAPT-----TPKAAAPNTPKEPAPTTPKEPAPTT- 558

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ--STSCPALPP 726
             +        T+P T +  ++ +   + A  + +    K LA   TK+  ST+C    P
Sbjct: 559 PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617

Query: 727 RAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             PK        E +P   K + A   PK  +P
Sbjct: 618 TTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAP 649



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 39/265 (14%)

Query: 509 TALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS----------IPPRTVKPAR 558
           T   P P  PK  A +E        P    S KP  T+P            P    KPA 
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710

Query: 559 QQTRSPSPTLSYYSSGLHNIVTKTDT----NPSESTP-VSCYPCNRVKTDSVDLKSPFGS 613
               +P PT S  S+      TK  T    +P ESTP +S  P  +   +S   K P G 
Sbjct: 711 TTPETPPPTTSEVST---PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEP-GV 764

Query: 614 PSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPR--QKTPGTPKRNCPAPFDFD 671
           P+ +  ++  + P   + A +  T  D    P  + + P+  ++T  T ++   +     
Sbjct: 765 PTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 822

Query: 672 GCELLAS---PTSPVTAEFSSSVSGCPK--SASYSLESTDVKSL---------AAGVTKQ 717
             ++ ++    T+P       + +  PK  +   ++ +T++ +           A  +K 
Sbjct: 823 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882

Query: 718 STSCPALPPRAPKLVEEKVASETSP 742
           +T  P  P +APK        +T P
Sbjct: 883 TTPKPQKPTKAPKKPTSTKKPKTMP 907



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 60/295 (20%), Positives = 107/295 (36%), Gaps = 27/295 (9%)

Query: 478 CDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPP 537
           C + + + +++    P P P  +  A    D        P  S    +  ++  +P +  
Sbjct: 63  CAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT--QHNKVSTSPKIT- 119

Query: 538 RSAKPLSTSPSIPPRT-VKPARQQTRSPSPTLSYYSSGLHNIVTKTD-----TNPSESTP 591
            +AKP++  PS+PP +        T +   T+    +   N  T TD     T+  E+  
Sbjct: 120 -TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 178

Query: 592 VSCYPCNRVKTDSVDLKSPFGSPSAEAVSS--RLSWPNHYSGASESQTRSDFLLDPSRSY 649
           +       +   S  L  P  +P AE  +    L+ P   +  +  +  S          
Sbjct: 179 IEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTTPKEPTPTTPKEPAS---------- 226

Query: 650 SYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKS 709
           + P++ TP T K     P +       ++PT+P     +++    P +      +T  K 
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKE 285

Query: 710 LAAGVTKQSTSCPALP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSE 763
            A   TK + + P  P P  PK        E +P   K +     PK  +P   E
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTPKEPAPTTKE 339



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 58/277 (20%), Positives = 89/277 (32%), Gaps = 49/277 (17%)

Query: 486 RSKCATSPL-PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           +   +T+P  P P T    +KS+ T  P  P P  +++           P  P+   P +
Sbjct: 222 KEPASTTPKEPTPTT----IKSAPTT-PKEPAPTTTKSA----------PTTPKEPAPTT 266

Query: 545 TSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDS 604
           T    P    +PA   T+ P+PT +            T   P+ +TP    P    +   
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTT-------KSAPTTPKEPAPTTPKKPAPTTPKEPAP 319

Query: 605 VDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
              K P   +P   A +++   P                       + P++  P  PK+ 
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAP-----------------------TTPKEPAPTAPKKP 356

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P             P    T E S +    P   +     T  K  A   TK + + P 
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416

Query: 724 LP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
            P P   K        E +P   K   A   PK  +P
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAP 452



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 51/245 (20%), Positives = 81/245 (33%), Gaps = 36/245 (14%)

Query: 506 SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
           +S T   P P  PK  A           P  P+   P +   + P    +PA    + P+
Sbjct: 608 TSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 664

Query: 566 PTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLS 624
           P           +   T   P+ +T     P    +T     K P   +P   A ++  +
Sbjct: 665 P---------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 715

Query: 625 WPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVT 684
            P   S  S   T      +P+  +  P + TP                EL A PT P  
Sbjct: 716 PPPTTSEVSTPTTTK----EPTTIHKSPDESTP----------------ELSAEPT-PKA 754

Query: 685 AEFSSSVSGCPKSASYSLESTDVKSLAAGVT--KQSTSCPALPPRAPKLVEEKVASETSP 742
            E S    G P + + +    ++ + A   T  +   + P     APK+ +E   +    
Sbjct: 755 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 814

Query: 743 LPLKI 747
              KI
Sbjct: 815 TESKI 819


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 60/273 (21%), Positives = 96/273 (35%), Gaps = 18/273 (6%)

Query: 491 TSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIP 550
           T+    P T      ++  + P  P  P     +E        P P    KP  T+P  P
Sbjct: 432 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 491

Query: 551 PRTV--KPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLK 608
             T   +PA   T+ P+PT     +      T  +T P  +TP    P    K      +
Sbjct: 492 APTTPKEPAPTTTKKPAPTTPKEPAP----TTPKETAP--TTPKKLTPTTPEKLAPTTPE 545

Query: 609 SPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPF 668
            P  +   E   +    P   +    + T        + + + P++  P TPK   P   
Sbjct: 546 KPAPTTPEELAPTTPEEPTPTTPEEPAPT-----TPKAAAPNTPKEPAPTTPKEPAPTT- 599

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ--STSCPALPP 726
             +        T+P T +  ++ +   + A  + +    K LA   TK+  ST+C    P
Sbjct: 600 PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658

Query: 727 RAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             PK        E +P   K + A   PK  +P
Sbjct: 659 TTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAP 690



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 39/265 (14%)

Query: 509 TALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS----------IPPRTVKPAR 558
           T   P P  PK  A +E        P    S KP  T+P            P    KPA 
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751

Query: 559 QQTRSPSPTLSYYSSGLHNIVTKTDT----NPSESTP-VSCYPCNRVKTDSVDLKSPFGS 613
               +P PT S  S+      TK  T    +P ESTP +S  P  +   +S   K P G 
Sbjct: 752 TTPETPPPTTSEVST---PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEP-GV 805

Query: 614 PSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPR--QKTPGTPKRNCPAPFDFD 671
           P+ +  ++  + P   + A +  T  D    P  + + P+  ++T  T ++   +     
Sbjct: 806 PTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 863

Query: 672 GCELLAS---PTSPVTAEFSSSVSGCPK--SASYSLESTDVKSL---------AAGVTKQ 717
             ++ ++    T+P       + +  PK  +   ++ +T++ +           A  +K 
Sbjct: 864 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923

Query: 718 STSCPALPPRAPKLVEEKVASETSP 742
           +T  P  P +APK        +T P
Sbjct: 924 TTPKPQKPTKAPKKPTSTKKPKTMP 948



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 60/295 (20%), Positives = 107/295 (36%), Gaps = 27/295 (9%)

Query: 478 CDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPP 537
           C + + + +++    P P P  +  A    D        P  S    +  ++  +P +  
Sbjct: 104 CAEVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTT--QHNKVSTSPKIT- 160

Query: 538 RSAKPLSTSPSIPPRT-VKPARQQTRSPSPTLSYYSSGLHNIVTKTD-----TNPSESTP 591
            +AKP++  PS+PP +        T +   T+    +   N  T TD     T+  E+  
Sbjct: 161 -TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQS 219

Query: 592 VSCYPCNRVKTDSVDLKSPFGSPSAEAVSS--RLSWPNHYSGASESQTRSDFLLDPSRSY 649
           +       +   S  L  P  +P AE  +    L+ P   +  +  +  S          
Sbjct: 220 IEKTSAKDLAPTSKVLAKP--TPKAETTTKGPALTTPKEPTPTTPKEPAS---------- 267

Query: 650 SYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKS 709
           + P++ TP T K     P +       ++PT+P     +++    P +      +T  K 
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKE 326

Query: 710 LAAGVTKQSTSCPALP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSE 763
            A   TK + + P  P P  PK        E +P   K +     PK  +P   E
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK-EPTPTTPKEPAPTTKE 380



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 58/277 (20%), Positives = 89/277 (32%), Gaps = 49/277 (17%)

Query: 486 RSKCATSPL-PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           +   +T+P  P P T    +KS+ T  P  P P  +++           P  P+   P +
Sbjct: 263 KEPASTTPKEPTPTT----IKSAPTT-PKEPAPTTTKSA----------PTTPKEPAPTT 307

Query: 545 TSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDS 604
           T    P    +PA   T+ P+PT +            T   P+ +TP    P    +   
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTT-------KSAPTTPKEPAPTTPKKPAPTTPKEPAP 360

Query: 605 VDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
              K P   +P   A +++   P                       + P++  P  PK+ 
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAP-----------------------TTPKEPAPTAPKKP 397

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P             P    T E S +    P   +     T  K  A   TK + + P 
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457

Query: 724 LP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
            P P   K        E +P   K   A   PK  +P
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAP 493



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 51/245 (20%), Positives = 81/245 (33%), Gaps = 36/245 (14%)

Query: 506 SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
           +S T   P P  PK  A           P  P+   P +   + P    +PA    + P+
Sbjct: 649 TSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 705

Query: 566 PTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLS 624
           P           +   T   P+ +T     P    +T     K P   +P   A ++  +
Sbjct: 706 P---------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 756

Query: 625 WPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVT 684
            P   S  S   T      +P+  +  P + TP                EL A PT P  
Sbjct: 757 PPPTTSEVSTPTTTK----EPTTIHKSPDESTP----------------ELSAEPT-PKA 795

Query: 685 AEFSSSVSGCPKSASYSLESTDVKSLAAGVT--KQSTSCPALPPRAPKLVEEKVASETSP 742
            E S    G P + + +    ++ + A   T  +   + P     APK+ +E   +    
Sbjct: 796 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 855

Query: 743 LPLKI 747
              KI
Sbjct: 856 TESKI 860


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 60/273 (21%), Positives = 96/273 (35%), Gaps = 18/273 (6%)

Query: 491 TSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIP 550
           T+    P T      ++  + P  P  P     +E        P P    KP  T+P  P
Sbjct: 484 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 543

Query: 551 PRTV--KPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLK 608
             T   +PA   T+ P+PT     +      T  +T P  +TP    P    K      +
Sbjct: 544 APTTPKEPAPTTTKKPAPTTPKEPAP----TTPKETAP--TTPKKLTPTTPEKLAPTTPE 597

Query: 609 SPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPF 668
            P  +   E   +    P   +    + T        + + + P++  P TPK   P   
Sbjct: 598 KPAPTTPEELAPTTPEEPTPTTPEEPAPT-----TPKAAAPNTPKEPAPTTPKEPAPTT- 651

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ--STSCPALPP 726
             +        T+P T +  ++ +   + A  + +    K LA   TK+  ST+C    P
Sbjct: 652 PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710

Query: 727 RAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             PK        E +P   K + A   PK  +P
Sbjct: 711 TTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAP 742



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 58/281 (20%), Positives = 93/281 (33%), Gaps = 49/281 (17%)

Query: 487 SKCATSPLPIPGTL--GAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           SK    P P   T   G A+ +     P  P  P S   +E           P + K   
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT---------PTTIKSAP 334

Query: 545 TSPSIP-PRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTD 603
           T+P  P P T K A    + P+PT              T   P+ +TP    P    +  
Sbjct: 335 TTPKEPAPTTTKSAPTTPKEPAPT--------------TTKEPAPTTPKEPAPTTTKEPA 380

Query: 604 SVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
               KS   +P   A ++    P   +  +  +           + + P++ TP TPK  
Sbjct: 381 PTTTKSAPTTPKEPAPTT----PKKPAPTTPKEP----------APTTPKEPTPTTPKEP 426

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P   +        +PT+P     ++     P +      +T  +       + S + P 
Sbjct: 427 APTTKE-------PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479

Query: 724 LPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSED 764
            P  AP   +    +   P P     A   PK  SP  +++
Sbjct: 480 EP--APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 39/265 (14%)

Query: 509  TALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS----------IPPRTVKPAR 558
            T   P P  PK  A +E        P    S KP  T+P            P    KPA 
Sbjct: 744  TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803

Query: 559  QQTRSPSPTLSYYSSGLHNIVTKTDT----NPSESTP-VSCYPCNRVKTDSVDLKSPFGS 613
                +P PT S  S+      TK  T    +P ESTP +S  P  +   +S   K P G 
Sbjct: 804  TTPETPPPTTSEVST---PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEP-GV 857

Query: 614  PSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPR--QKTPGTPKRNCPAPFDFD 671
            P+ +  ++  + P   + A +  T  D    P  + + P+  ++T  T ++   +     
Sbjct: 858  PTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 915

Query: 672  GCELLAS---PTSPVTAEFSSSVSGCPK--SASYSLESTDVKSL---------AAGVTKQ 717
              ++ ++    T+P       + +  PK  +   ++ +T++ +           A  +K 
Sbjct: 916  TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975

Query: 718  STSCPALPPRAPKLVEEKVASETSP 742
            +T  P  P +APK        +T P
Sbjct: 976  TTPKPQKPTKAPKKPTSTKKPKTMP 1000



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 65/308 (21%), Positives = 100/308 (32%), Gaps = 46/308 (14%)

Query: 484 SVRSKCATSPLPIPGTLGAAVKSSDTALP-----PPPVPPKSEA----------VREECR 528
           +++S   T   P P T  +A  +     P     P P  PK  A            +   
Sbjct: 329 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 388

Query: 529 LLNAPPVPPRSAKPLSTSPSIP---------PRTVKPARQQTRSPSPTLSYYSSGLHNIV 579
                P P    KP  T+P  P         P T K     T+ P+PT            
Sbjct: 389 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP------KEPA 442

Query: 580 TKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTR 638
                 P+ +TP    P    +      K P   +P   A ++  S P      + + T+
Sbjct: 443 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 502

Query: 639 SDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSA 698
           S        S +  ++  P TPK   PAP          +PT+P     ++     P + 
Sbjct: 503 SAPTTPKEPSPTTTKEPAPTTPKE--PAP----TTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 699 SYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAE------E 752
                +T  +   A  T + T+ P  P +      EK+A  T   P      E      E
Sbjct: 557 KKPAPTTPKE--PAPTTPKETA-PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 613

Query: 753 DPKSGSPD 760
           +P   +P+
Sbjct: 614 EPTPTTPE 621



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 58/277 (20%), Positives = 89/277 (32%), Gaps = 49/277 (17%)

Query: 486 RSKCATSPL-PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           +   +T+P  P P T    +KS+ T  P  P P  +++           P  P+   P +
Sbjct: 315 KEPASTTPKEPTPTT----IKSAPTT-PKEPAPTTTKSA----------PTTPKEPAPTT 359

Query: 545 TSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDS 604
           T    P    +PA   T+ P+PT +            T   P+ +TP    P    +   
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTT-------KSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 605 VDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
              K P   +P   A +++   P                       + P++  P  PK+ 
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAP-----------------------TTPKEPAPTAPKKP 449

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P             P    T E S +    P   +     T  K  A   TK + + P 
Sbjct: 450 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509

Query: 724 LP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
            P P   K        E +P   K   A   PK  +P
Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAP 545



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 51/245 (20%), Positives = 81/245 (33%), Gaps = 36/245 (14%)

Query: 506 SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
           +S T   P P  PK  A           P  P+   P +   + P    +PA    + P+
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 757

Query: 566 PTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLS 624
           P           +   T   P+ +T     P    +T     K P   +P   A ++  +
Sbjct: 758 P---------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 808

Query: 625 WPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVT 684
            P   S  S   T      +P+  +  P + TP                EL A PT P  
Sbjct: 809 PPPTTSEVSTPTTTK----EPTTIHKSPDESTP----------------ELSAEPT-PKA 847

Query: 685 AEFSSSVSGCPKSASYSLESTDVKSLAAGVT--KQSTSCPALPPRAPKLVEEKVASETSP 742
            E S    G P + + +    ++ + A   T  +   + P     APK+ +E   +    
Sbjct: 848 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 907

Query: 743 LPLKI 747
              KI
Sbjct: 908 TESKI 912



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 60/294 (20%), Positives = 96/294 (32%), Gaps = 59/294 (20%)

Query: 495 PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTV 554
           P P      +KS+    P PP   K++ V E   +     V        S+S S    T+
Sbjct: 79  PPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTI 138

Query: 555 KPARQQTRSPS--------------------------PTLSYYSSGLHN---IVTKTDTN 585
           +  +    S +                          P +    SGL N    VT  DT+
Sbjct: 139 RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS 198

Query: 586 PSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDP 645
            ++   VS  P  ++ T             A+ ++ R S P        S T  +  L  
Sbjct: 199 TTQHNKVSTSP--KITT-------------AKPINPRPSLP------PNSDTSKETSLTV 237

Query: 646 SRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLEST 705
           ++  +   ++T  T K+        DG E   S     + E +S+    P S   +  + 
Sbjct: 238 NKETTVETKETTTTNKQT-----STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 292

Query: 706 DVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             ++   G    +   P   P  PK  E    +   P P  I  A   PK  +P
Sbjct: 293 KAETTTKGPALTTPKEPT--PTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAP 342


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 60/273 (21%), Positives = 96/273 (35%), Gaps = 18/273 (6%)

Query: 491 TSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIP 550
           T+    P T      ++  + P  P  P     +E        P P    KP  T+P  P
Sbjct: 525 TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEP 584

Query: 551 PRTV--KPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLK 608
             T   +PA   T+ P+PT     +      T  +T P  +TP    P    K      +
Sbjct: 585 APTTPKEPAPTTTKKPAPTTPKEPAP----TTPKETAP--TTPKKLTPTTPEKLAPTTPE 638

Query: 609 SPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPF 668
            P  +   E   +    P   +    + T        + + + P++  P TPK   P   
Sbjct: 639 KPAPTTPEELAPTTPEEPTPTTPEEPAPT-----TPKAAAPNTPKEPAPTTPKEPAPTT- 692

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ--STSCPALPP 726
             +        T+P T +  ++ +   + A  + +    K LA   TK+  ST+C    P
Sbjct: 693 PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751

Query: 727 RAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             PK        E +P   K + A   PK  +P
Sbjct: 752 TTPKGTAPTTPKEPAPTTPK-EPAPTTPKGTAP 783



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 58/281 (20%), Positives = 93/281 (33%), Gaps = 49/281 (17%)

Query: 487 SKCATSPLPIPGTL--GAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           SK    P P   T   G A+ +     P  P  P S   +E           P + K   
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT---------PTTIKSAP 375

Query: 545 TSPSIP-PRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTD 603
           T+P  P P T K A    + P+PT              T   P+ +TP    P    +  
Sbjct: 376 TTPKEPAPTTTKSAPTTPKEPAPT--------------TTKEPAPTTPKEPAPTTTKEPA 421

Query: 604 SVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
               KS   +P   A ++    P   +  +  +           + + P++ TP TPK  
Sbjct: 422 PTTTKSAPTTPKEPAPTT----PKKPAPTTPKEP----------APTTPKEPTPTTPKEP 467

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P   +        +PT+P     ++     P +      +T  +       + S + P 
Sbjct: 468 APTTKE-------PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520

Query: 724 LPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSED 764
            P  AP   +    +   P P     A   PK  SP  +++
Sbjct: 521 EP--APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 39/265 (14%)

Query: 509  TALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS----------IPPRTVKPAR 558
            T   P P  PK  A +E        P    S KP  T+P            P    KPA 
Sbjct: 785  TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844

Query: 559  QQTRSPSPTLSYYSSGLHNIVTKTDT----NPSESTP-VSCYPCNRVKTDSVDLKSPFGS 613
                +P PT S  S+      TK  T    +P ESTP +S  P  +   +S   K P G 
Sbjct: 845  TTPETPPPTTSEVST---PTTTKEPTTIHKSPDESTPELSAEPTPKALENSP--KEP-GV 898

Query: 614  PSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPR--QKTPGTPKRNCPAPFDFD 671
            P+ +  ++  + P   + A +  T  D    P  + + P+  ++T  T ++   +     
Sbjct: 899  PTTKTPAA--TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 956

Query: 672  GCELLAS---PTSPVTAEFSSSVSGCPK--SASYSLESTDVKSL---------AAGVTKQ 717
              ++ ++    T+P       + +  PK  +   ++ +T++ +           A  +K 
Sbjct: 957  TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016

Query: 718  STSCPALPPRAPKLVEEKVASETSP 742
            +T  P  P +APK        +T P
Sbjct: 1017 TTPKPQKPTKAPKKPTSTKKPKTMP 1041



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 65/308 (21%), Positives = 100/308 (32%), Gaps = 46/308 (14%)

Query: 484 SVRSKCATSPLPIPGTLGAAVKSSDTALP-----PPPVPPKSEA----------VREECR 528
           +++S   T   P P T  +A  +     P     P P  PK  A            +   
Sbjct: 370 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 429

Query: 529 LLNAPPVPPRSAKPLSTSPSIP---------PRTVKPARQQTRSPSPTLSYYSSGLHNIV 579
                P P    KP  T+P  P         P T K     T+ P+PT            
Sbjct: 430 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP------KEPA 483

Query: 580 TKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTR 638
                 P+ +TP    P    +      K P   +P   A ++  S P      + + T+
Sbjct: 484 PTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTK 543

Query: 639 SDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSA 698
           S        S +  ++  P TPK   PAP          +PT+P     ++     P + 
Sbjct: 544 SAPTTPKEPSPTTTKEPAPTTPKE--PAP----TTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 699 SYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAE------E 752
                +T  +   A  T + T+ P  P +      EK+A  T   P      E      E
Sbjct: 598 KKPAPTTPKE--PAPTTPKETA-PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE 654

Query: 753 DPKSGSPD 760
           +P   +P+
Sbjct: 655 EPTPTTPE 662



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 58/277 (20%), Positives = 89/277 (32%), Gaps = 49/277 (17%)

Query: 486 RSKCATSPL-PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS 544
           +   +T+P  P P T    +KS+ T  P  P P  +++           P  P+   P +
Sbjct: 356 KEPASTTPKEPTPTT----IKSAPTT-PKEPAPTTTKSA----------PTTPKEPAPTT 400

Query: 545 TSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDS 604
           T    P    +PA   T+ P+PT +            T   P+ +TP    P    +   
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTT-------KSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 605 VDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
              K P   +P   A +++   P                       + P++  P  PK+ 
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAP-----------------------TTPKEPAPTAPKKP 490

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
            P             P    T E S +    P   +     T  K  A   TK + + P 
Sbjct: 491 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550

Query: 724 LP-PRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
            P P   K        E +P   K   A   PK  +P
Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTPK-KPAPTTPKEPAP 586



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 51/245 (20%), Positives = 81/245 (33%), Gaps = 36/245 (14%)

Query: 506 SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
           +S T   P P  PK  A           P  P+   P +   + P    +PA    + P+
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTP---KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPA 798

Query: 566 PTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLS 624
           P           +   T   P+ +T     P    +T     K P   +P   A ++  +
Sbjct: 799 P---------KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPET 849

Query: 625 WPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVT 684
            P   S  S   T      +P+  +  P + TP                EL A PT P  
Sbjct: 850 PPPTTSEVSTPTTTK----EPTTIHKSPDESTP----------------ELSAEPT-PKA 888

Query: 685 AEFSSSVSGCPKSASYSLESTDVKSLAAGVT--KQSTSCPALPPRAPKLVEEKVASETSP 742
            E S    G P + + +    ++ + A   T  +   + P     APK+ +E   +    
Sbjct: 889 LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKT 948

Query: 743 LPLKI 747
              KI
Sbjct: 949 TESKI 953



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 60/294 (20%), Positives = 96/294 (32%), Gaps = 59/294 (20%)

Query: 495 PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTV 554
           P P      +KS+    P PP   K++ V E   +     V        S+S S    T+
Sbjct: 120 PPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTI 179

Query: 555 KPARQQTRSPS--------------------------PTLSYYSSGLHN---IVTKTDTN 585
           +  +    S +                          P +    SGL N    VT  DT+
Sbjct: 180 RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS 239

Query: 586 PSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDP 645
            ++   VS  P  ++ T             A+ ++ R S P        S T  +  L  
Sbjct: 240 TTQHNKVSTSP--KITT-------------AKPINPRPSLP------PNSDTSKETSLTV 278

Query: 646 SRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLEST 705
           ++  +   ++T  T K+        DG E   S     + E +S+    P S   +  + 
Sbjct: 279 NKETTVETKETTTTNKQT-----STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTP 333

Query: 706 DVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSP 759
             ++   G    +   P   P  PK  E    +   P P  I  A   PK  +P
Sbjct: 334 KAETTTKGPALTTPKEPT--PTTPK--EPASTTPKEPTPTTIKSAPTTPKEPAP 383


>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
          Length = 1952

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 79/314 (25%), Positives = 111/314 (35%), Gaps = 46/314 (14%)

Query: 468 LTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTA----LPPPPVPPKSEAV 523
           +T S + K+  D    S  S+ +T     PG  G  +  S +A    +  P   P + A 
Sbjct: 123 ITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSAS 182

Query: 524 REECRLLNAPPVPPRSAKPLS--TSPSIPPRTVKPARQQTRS-----------PSPT--- 567
            E   L  +      S K  +  +SP  P RT+ PAR  +             P PT   
Sbjct: 183 METTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI 242

Query: 568 ----------LSYYSSGLHNIVTKTDT--NPSESTPVSCYPCNRVKTDSVDLKSPFGSPS 615
                     +S  S+  H+I   TDT  +P  +TP S  P +     S         P 
Sbjct: 243 AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 302

Query: 616 AEAVSSRL--SWPNHYSGASESQTRSDFLL-----DPSRSYSYPRQKTPGTPKRNCPAPF 668
               S  L  S P H S  S   T S         +P+   S+P  K          + F
Sbjct: 303 NTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF 362

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRA 728
                   +SP+S  T  FS+S +    +  +S EST V S        +T+ P      
Sbjct: 363 VKLSTTYHSSPSSTPTTHFSASST----TLGHSEESTPVHSSPVAT---ATTPPPARSAT 415

Query: 729 PKLVEEKVASETSP 742
              VEE  A   SP
Sbjct: 416 SGHVEESTAYHRSP 429



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 54/240 (22%), Positives = 87/240 (36%), Gaps = 36/240 (15%)

Query: 487 SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRS------- 539
           S+ +T+   IPG+    +    T   P  + P+S              +P  +       
Sbjct: 254 SQESTASHSIPGSTDTTLSPGTTT--PSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLE 311

Query: 540 -AKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCN 598
            + P+ +S   P  T+ PA   T    PT         +  +  DT+P+ S   S +   
Sbjct: 312 ASTPVHSSTGSPHTTLSPASSTTHEGEPTT------FQSWPSSKDTSPAPSGTTSAF--- 362

Query: 599 RVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPG 658
            VK  +    SP  +P+            H+S +S +   S+    P  S       TP 
Sbjct: 363 -VKLSTTYHSSPSSTPT-----------THFSASSTTLGHSE-ESTPVHSSPVATATTP- 408

Query: 659 TPKRNCPAPFDFDGCELLASPTSPVTAEF--SSSVSG-CPKSASYSLESTDVKSLAAGVT 715
            P R+  +    +      SP S  T  F  SS+ SG   +SA++   +T  KS     T
Sbjct: 409 PPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTT 468


>gi|239749217 PREDICTED: similar to Mucin-12, partial [Homo sapiens]
          Length = 861

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 79/314 (25%), Positives = 111/314 (35%), Gaps = 46/314 (14%)

Query: 468 LTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTA----LPPPPVPPKSEAV 523
           +T S + K+  D    S  S+ +T     PG  G  +  S +A    +  P   P + A 
Sbjct: 58  ITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSAS 117

Query: 524 REECRLLNAPPVPPRSAKPLS--TSPSIPPRTVKPARQQTRS-----------PSPT--- 567
            E   L  +      S K  +  +SP  P RT+ PAR  +             P PT   
Sbjct: 118 METTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI 177

Query: 568 ----------LSYYSSGLHNIVTKTDT--NPSESTPVSCYPCNRVKTDSVDLKSPFGSPS 615
                     +S  S+  H+I   TDT  +P  +TP S  P +     S         P 
Sbjct: 178 AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 237

Query: 616 AEAVSSRL--SWPNHYSGASESQTRSDFLL-----DPSRSYSYPRQKTPGTPKRNCPAPF 668
               S  L  S P H S  S   T S         +P+   S+P  K          + F
Sbjct: 238 NTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF 297

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRA 728
                   +SP+S  T  FS+S +    +  +S EST V S        +T+ P      
Sbjct: 298 VKLSTTYHSSPSSTPTTHFSASST----TLGHSEESTPVHSSPVAT---ATTPPPARSAT 350

Query: 729 PKLVEEKVASETSP 742
              VEE  A   SP
Sbjct: 351 SGHVEESTAYHRSP 364


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 79/314 (25%), Positives = 111/314 (35%), Gaps = 46/314 (14%)

Query: 468 LTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTA----LPPPPVPPKSEAV 523
           +T S + K+  D    S  S+ +T     PG  G  +  S +A    +  P   P + A 
Sbjct: 202 ITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSAS 261

Query: 524 REECRLLNAPPVPPRSAKPLS--TSPSIPPRTVKPARQQTRS-----------PSPT--- 567
            E   L  +      S K  +  +SP  P RT+ PAR  +             P PT   
Sbjct: 262 METTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTI 321

Query: 568 ----------LSYYSSGLHNIVTKTDT--NPSESTPVSCYPCNRVKTDSVDLKSPFGSPS 615
                     +S  S+  H+I   TDT  +P  +TP S  P +     S         P 
Sbjct: 322 AFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 381

Query: 616 AEAVSSRL--SWPNHYSGASESQTRSDFLL-----DPSRSYSYPRQKTPGTPKRNCPAPF 668
               S  L  S P H S  S   T S         +P+   S+P  K          + F
Sbjct: 382 NTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAF 441

Query: 669 DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRA 728
                   +SP+S  T  FS+S +    +  +S EST V S        +T+ P      
Sbjct: 442 VKLSTTYHSSPSSTPTTHFSASST----TLGHSEESTPVHSSPVAT---ATTPPPARSAT 494

Query: 729 PKLVEEKVASETSP 742
              VEE  A   SP
Sbjct: 495 SGHVEESTAYHRSP 508



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 87/348 (25%), Positives = 122/348 (35%), Gaps = 54/348 (15%)

Query: 435  FPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPL 494
            +P +S+ +   PG +  P E       +PS  P T   +            RS+ +T+  
Sbjct: 1586 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG------RSEESTTVH 1639

Query: 495  PIPGTLGAAV----KSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS--TSPS 548
              PG  G A+     ++   +  P   P S    E   L  +      S K  +  +SP 
Sbjct: 1640 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1699

Query: 549  IPPRTVKPA--------RQQTRSPS----------------PTLSYYSSGLHNIVTKTDT 584
             P  T+ PA         + T S S                P +S  S+  H+    TDT
Sbjct: 1700 SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 1759

Query: 585  --NPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRL--SWPNHYSGASESQTRSD 640
              +P  +T  S  P +     S         P     S  L  S P H S  S   T S 
Sbjct: 1760 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1819

Query: 641  FLLDPSRSYSYPRQKTPGTPKRNCPAP------FDFDGCELLASPTSPVTAEFSSSVSGC 694
                  +  S   Q  P + K   PAP      F         SP+S  T  FS+S +  
Sbjct: 1820 AGSTTRQGESTTFQSWPSS-KDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1878

Query: 695  PKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSP 742
             +S     EST V S  + V   +T  PA    +  LVEE  A  +SP
Sbjct: 1879 GRSE----ESTTVHS--SPVATATTPSPARSTTS-GLVEESTAYHSSP 1919



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 23/248 (9%)

Query: 506  SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
            S+DTAL P      S   +E     ++P     +  P ST+ S            T SP 
Sbjct: 2142 STDTALSPGSTTALSFG-QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 2200

Query: 566  PTLSYYSS---GLHNIVTKTDTNPSESTPVSCYPCNR---VKTDSVDLKSPFGSPSAEAV 619
             TLS  SS   GL    T   T+P+ +      P      V+  +   +SP  +P+    
Sbjct: 2201 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 2260

Query: 620  SSRLSWPNHYSGASESQTRSDFLLD-----PSRSYSYPRQKTPGTPKRNCPAPFDFDGCE 674
            +S  +     SG SE  T      D     PS ++S    +   T  R  P   +     
Sbjct: 2261 ASSTT-----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT--T 2313

Query: 675  LLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
            L  S T+P  +E S++    P+S + +L    + SL  GV ++ST+  + P      V  
Sbjct: 2314 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEESTTSRSQPGSTHSTVSP 2371

Query: 735  KVASETSP 742
              AS T+P
Sbjct: 2372 --ASTTTP 2377



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 23/248 (9%)

Query: 506  SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
            S+DTAL P      S   +E     ++P     +  P ST+ S            T SP 
Sbjct: 2616 STDTALSPGSTTALSFG-QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 2674

Query: 566  PTLSYYSS---GLHNIVTKTDTNPSESTPVSCYPCNR---VKTDSVDLKSPFGSPSAEAV 619
             TLS  SS   GL    T   T+P+ +      P      V+  +   +SP  +P+    
Sbjct: 2675 TTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 2734

Query: 620  SSRLSWPNHYSGASESQTRSDFLLD-----PSRSYSYPRQKTPGTPKRNCPAPFDFDGCE 674
            +S  +     SG SE  T      D     PS ++S    +   T  R  P   +     
Sbjct: 2735 ASSTT-----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT--T 2787

Query: 675  LLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
            L  S T+P  +E S++    P+S + +L    + SL  GV ++ST+  + P      V  
Sbjct: 2788 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEESTTSRSQPGSTHSTVSP 2845

Query: 735  KVASETSP 742
              AS T+P
Sbjct: 2846 --ASTTTP 2851



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 65/248 (26%), Positives = 98/248 (39%), Gaps = 23/248 (9%)

Query: 506  SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
            S+DTAL P      S   +E     ++P     +  P ST+ S            T SP 
Sbjct: 3699 STDTALSPGSTTALSFG-QESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 3757

Query: 566  PTLSYYSS---GLHNIVTKTDTNPSESTPVSCYPCNR---VKTDSVDLKSPFGSPSAEAV 619
             TLS  SS   GL    T   T+P+ +      P      V+  +   +SP  +P+    
Sbjct: 3758 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 3817

Query: 620  SSRLSWPNHYSGASESQTRSDFLLD-----PSRSYSYPRQKTPGTPKRNCPAPFDFDGCE 674
            +S  +     SG SE  T      D     PS ++S    +   T  R  P   +     
Sbjct: 3818 ASSTT-----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT--T 3870

Query: 675  LLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
            L  S T+P  +E S++    P+S + +L    + SL  GV ++ST+  + P      V  
Sbjct: 3871 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEESTTSRSQPGSTHSTVSP 3928

Query: 735  KVASETSP 742
              AS T+P
Sbjct: 3929 --ASTTTP 3934



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 65/248 (26%), Positives = 97/248 (39%), Gaps = 23/248 (9%)

Query: 506  SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
            S+DTAL P      S   +E     + P     +  P ST+ S            T SP 
Sbjct: 1059 STDTALSPGSTTALSFG-QESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 1117

Query: 566  PTLSYYSS---GLHNIVTKTDTNPSESTPVSCYPCNR---VKTDSVDLKSPFGSPSAEAV 619
             TLS  SS   GL    T   T+P+ +      P      V+  +   +SP  +P+    
Sbjct: 1118 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 1177

Query: 620  SSRLSWPNHYSGASESQTRSDFLLD-----PSRSYSYPRQKTPGTPKRNCPAPFDFDGCE 674
            +S  +     SG SE  T      D     PS ++S    +   T  R  P   +     
Sbjct: 1178 ASSTT-----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT--T 1230

Query: 675  LLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
            L  S T+P  +E S++    P+S + +L    + SL  GV ++ST+  + P      V  
Sbjct: 1231 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEESTTSRSQPGSTHSTVSP 1288

Query: 735  KVASETSP 742
              AS T+P
Sbjct: 1289 --ASTTTP 1294



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 89/354 (25%), Positives = 124/354 (35%), Gaps = 66/354 (18%)

Query: 435  FPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPL 494
            +P +S+ +   PG +  P E       +PS  P T   +            RS+ +T+  
Sbjct: 3143 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG------RSEESTTVH 3196

Query: 495  PIPGTLGAAV----KSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS--TSPS 548
              PG  G A+     ++   +  P   P S    E   L  +      S K  +  +SP 
Sbjct: 3197 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 3256

Query: 549  IPPRTVKPA--------RQQTRSPS----------------PTLSYYSSGLHNIVTKTDT 584
             P  T+ PA         + T S S                P +S  S+  H+    TDT
Sbjct: 3257 SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 3316

Query: 585  --NPSESTPVSCYPCNRVKTDSVDLKSPFGS------PSAEAVSSRL--SWPNHYSGASE 634
              +P  +T  S  P      +S    S  GS      P     S  L  S P H S  S 
Sbjct: 3317 TLSPGSTTASSLGP------ESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSP 3370

Query: 635  SQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAP------FDFDGCELLASPTSPVTAEFS 688
              T S       +  S   Q  P + K   PAP      F         SP+S  T  FS
Sbjct: 3371 HTTLSPAGSTTRQGESTTFQSWPNS-KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFS 3429

Query: 689  SSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSP 742
            +S +   +S     EST V S  + V   +T  PA    +  LVEE     +SP
Sbjct: 3430 ASSTTLGRSE----ESTTVHS--SPVATATTPSPARSTTS-GLVEESTTYHSSP 3476



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 85/348 (24%), Positives = 121/348 (34%), Gaps = 54/348 (15%)

Query: 435  FPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPL 494
            +P +S+ +   P  + +P E       +PS  P T   +            RS+ +T+  
Sbjct: 4226 WPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLG------RSEESTTVH 4279

Query: 495  PIPGTLGAAV----KSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS--TSPS 548
              PG  G A+     ++   +  P   P S    E   L  +      S K  +  +SP 
Sbjct: 4280 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 4339

Query: 549  IPPRTVKPA--------RQQTRSPS----------------PTLSYYSSGLHNIVTKTDT 584
             P  T+ PA         + T S S                P +S  S+  H+    TDT
Sbjct: 4340 SPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDT 4399

Query: 585  --NPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRL--SWPNHYSGASESQTRSD 640
              +P  +T  S  P +     S         P     S  L  S P H S  S   T S 
Sbjct: 4400 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 4459

Query: 641  FLLDPSRSYSYPRQKTPGTPKRNCPAP------FDFDGCELLASPTSPVTAEFSSSVSGC 694
                  +  S   Q  P + K   PAP      F         SP+S  T  FS+S +  
Sbjct: 4460 AGSTTRQGESTTFQSWPNS-KDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 4518

Query: 695  PKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSP 742
             +S     EST V S  + V   +T  PA    +  LVEE     +SP
Sbjct: 4519 GRSE----ESTTVHS--SPVATATTPSPARSTTS-GLVEESTTYHSSP 4559



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 52/235 (22%), Positives = 84/235 (35%), Gaps = 34/235 (14%)

Query: 532  APPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTP 591
            APP    +   LST+    P +         S +   S  S+ +H+    T T PS    
Sbjct: 4484 APPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS---- 4539

Query: 592  VSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSY 651
                P     +  V+  + + S      +      N  SG  E  T S        S ++
Sbjct: 4540 ----PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTS------HSSTTH 4589

Query: 652  PRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLA 711
                 P T               L+  PTS  ++  S++ +  P S++ S  S +  S A
Sbjct: 4590 TISSAPSTTS------------ALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE--STA 4635

Query: 712  AGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGS---PDLSE 763
            +  ++ +T    LP R+   V   +  E++  P+     E     GS   P LSE
Sbjct: 4636 SHSSQDATGTIVLPARSTTSV---LLGESTTSPISSGSMETTALPGSTTTPGLSE 4687



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 61/303 (20%), Positives = 100/303 (33%), Gaps = 15/303 (4%)

Query: 426  SGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSV 485
            S D+    + P  S  S  +   +  P     +E         T  LSEK+    F  S 
Sbjct: 4639 SQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTT--FHSSP 4696

Query: 486  RSKCATSPLPIPGTLGAAVKSSD-------TALPPPPVPPKSEAVREECRLLNAPPVPPR 538
             S   T       TLG + +S+        TA  P P    +  + EE    ++ P   +
Sbjct: 4697 SSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQ 4756

Query: 539  SAK-PLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPC 597
            +   P S++ S      + +   T     +    +S L    T   ++P           
Sbjct: 4757 TMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPES 4816

Query: 598  NRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP 657
            +     S +  +   SP    ++     P H++ +      + F + P  S       T 
Sbjct: 4817 STTSGRSEESTASHSSPDTNGITPL---PAHFTTSGRIAESTTFYISPG-SMETTLASTA 4872

Query: 658  GTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ 717
             TP  +  +   +          SP +   SSS+SG P S     EST   +  A  T  
Sbjct: 4873 TTPGLSAKSTILYSSSRSPDQTLSPASMT-SSSISGEPTSLYSQAESTHTTAFPASTTTS 4931

Query: 718  STS 720
              S
Sbjct: 4932 GLS 4934


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 56/225 (24%), Positives = 82/225 (36%), Gaps = 35/225 (15%)

Query: 442 SAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLG 501
           ++G  G+ + P+ E      +    P T +    +  +      + K AT P P P    
Sbjct: 299 ASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPE--- 355

Query: 502 AAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQT 561
              +SS    PP P P  +E         +     P +  PLS  P  PP    P R ++
Sbjct: 356 ---RSSTGPEPPAPTPLLAER--------HGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404

Query: 562 RSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPS----AE 617
              SP     SS             SES+P S  P    +  S   +SP  +P+     E
Sbjct: 405 PPKSPEKLPQSSS------------SESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452

Query: 618 AVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKR 662
             SS  S    +  A   ++ S     PSR     R ++P T KR
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSH---TPSRRMG--RSRSPATAKR 492



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 55/227 (24%), Positives = 83/227 (36%), Gaps = 27/227 (11%)

Query: 533  PPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPV 592
            P  PPR +   S SP    +   P       P P+LS   S       K+  +  +S P 
Sbjct: 981  PETPPRQSHSGSISPYPKVKAQTP-------PGPSLSGSKSPCPQ--EKSKDSLVQSCPG 1031

Query: 593  SCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYP 652
            S   C  VK+ +   +S FG  S +      + P+H S  S  + R      PS      
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 653  RQKTPGTPKRNCP-------APFDFDGCELLASP-----TSPVTAEFSSSVSGCPKSASY 700
                 G  + + P       +P   D  E  ASP      SP  + F S  S  P     
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYP----- 1146

Query: 701  SLESTDVKSLAAGVTKQSTSCPALPPRAPKLVE-EKVASETSPLPLK 746
            +++S  +   +   T +S    ALPP+        +   + SP P++
Sbjct: 1147 TVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQ 1193



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 82/348 (23%), Positives = 131/348 (37%), Gaps = 39/348 (11%)

Query: 424  QDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRG 483
            + SG S S+ L P+A E+ AG+     +    L      PS +  + + S + +    R 
Sbjct: 1377 RSSGHSSSE-LSPDAVEK-AGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRT 1434

Query: 484  -SVRSKCATSPLPIPGTLGAAVKSSDTALPP--PPVPPKSEAVREECRLLNAPPVPPRSA 540
             S RS+  +SP    G+ G   + S +   P    +P      R EC     P   P++ 
Sbjct: 1435 PSRRSRSGSSPGLRDGS-GTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP 1493

Query: 541  KPLSTSPSIPP---RTVKPARQQTRSPSPT-----------LSYYSSGLHNIVTKTDTNP 586
            +P S SPS P    + + P R+++ S S                 S     +  K   +P
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553

Query: 587  SESTPVSCYPCNRVKTDS-VDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDP 645
             E +     P ++ KT + +  +S  GS       SRLS     SG+S        + D 
Sbjct: 1554 QERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE------VKDK 1607

Query: 646  SRSYSYPRQKTPGTPKRNCPAPFDFDGCELLAS------PTSPVTAEFSSSVSGCPKS-- 697
             R+    +  +  +P+   PAP          S      P+   ++   SS    PKS  
Sbjct: 1608 PRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRT 1667

Query: 698  ---ASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSP 742
                S S      KS      + S S P L  +A +L     ++ +SP
Sbjct: 1668 ARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA-RLSRRSRSASSSP 1714



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 63/241 (26%), Positives = 97/241 (40%), Gaps = 26/241 (10%)

Query: 536  PPRSAKPLSTSPS----IPPRTVK-----PARQQTRSPSPTLSYYSSGLHNIVTKTDTNP 586
            PPR ++  S+ P      PPR  +     P +Q++++PS   S+ SS  H  V K+ T P
Sbjct: 793  PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS-RQSHSSSSPHPKV-KSGTPP 850

Query: 587  SESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDF--LLD 644
             + +  S  P    ++ +   +S F S     + SR    +  SG+S  + +S       
Sbjct: 851  RQGSITS--PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908

Query: 645  PSRSYS-YPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLE 703
            PSRS S  P+ K   +P++   +         + S T+P     S SVS C    S  L 
Sbjct: 909  PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP---RRSRSVSPCSNVESRLLP 965

Query: 704  STDVKSLAAGVTKQSTSCPALPPRAPKLVE----EKVASETSPLPLKIDGAEEDPKSGSP 759
                   ++  TK     P  PPR           KV ++T P P         P+  S 
Sbjct: 966  RYSHSGSSSPDTKVK---PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSK 1022

Query: 760  D 760
            D
Sbjct: 1023 D 1023



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 81/332 (24%), Positives = 121/332 (36%), Gaps = 33/332 (9%)

Query: 486  RSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLST 545
            RS  AT+P+ I G+  AA      AL P  +     A       L +P VP  + + +S 
Sbjct: 2342 RSAHATAPVNIAGSRTAA------ALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG 2395

Query: 546  SPSIP------PRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNR 599
              S P       RT   A  Q+R  S      SS +    +++   P++  P S  P   
Sbjct: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVP--- 2452

Query: 600  VKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGT 659
                S   +      +  A S  LS     SGA  + T S    D +   S P    P +
Sbjct: 2453 -SAFSDQSRCLIAQTTPVAGSQSLS-----SGAVATTTSSAG--DHNGMLSVPAPGVPHS 2504

Query: 660  PKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQST 719
                 PA         LA+   P     SSS S    S+S S  S+   S ++G +   +
Sbjct: 2505 DVGEPPASTGAQQPSALAA-LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS 2563

Query: 720  SCPALPPRAPKLVEEKVASET-SPLPLKIDGAEEDP-------KSGSPDLSEDQYFVKKG 771
               +LP + P++  ++V S T +P     +G   +P       +S S   S         
Sbjct: 2564 EGSSLPVQ-PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622

Query: 772  MQDIFSASYPFSSPLHLQLAPRSCGDGSPWQP 803
                 S+S   SS      +  S    SP +P
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP 2654



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 60/275 (21%), Positives = 97/275 (35%), Gaps = 25/275 (9%)

Query: 486  RSKCATSPLPIPGT-LGAAVKSSDTALPPPPVPPKS---EAVREECRLLNAPPVPPRSAK 541
            +S+  +   P P + +G A   S + LPP    P+S    A  ++ R L A   P   ++
Sbjct: 2416 QSRMTSERAPSPSSRMGQA--PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQ 2473

Query: 542  PLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGL-HNIVTKTDTNPSESTPVSCYPCNRV 600
             LS+        V          +  LS  + G+ H+ V +   +     P +       
Sbjct: 2474 SLSSG------AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA 2527

Query: 601  KTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP--- 657
            K       S   S S+ + SS  S  +    +S     S   + P  +       TP   
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587

Query: 658  -----GTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAA 712
                 G P    PA          +S +S  ++  SSS S    S+S S  S+   S ++
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647

Query: 713  GVTKQSTSCPALP----PRAPKLVEEKVASETSPL 743
              +       ALP    P+ P   E +  S   P+
Sbjct: 2648 SPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 62/291 (21%), Positives = 110/291 (37%), Gaps = 20/291 (6%)

Query: 486 RSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLST 545
           R++ A  P P P    + V+ S ++  P P   K +  ++  R   +    PR  +  S+
Sbjct: 156 RAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGR--RSESSSPRRERKKSS 213

Query: 546 SPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSV 605
                    +  +++ RSP+P     S       +++ T   +S            + S 
Sbjct: 214 KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSD 273

Query: 606 DLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCP 665
             +S   S +A+  ++ L+  +  S AS  +   D       + S  R  +P T  +   
Sbjct: 274 TSRSRSRSAAAKTHTTALAGRSP-SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332

Query: 666 APF-DFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKS---LAAGVTKQSTSC 721
           +P+ D D  +   S T P  +   SS    P + +  L      S   LA     Q    
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392

Query: 722 PAL---------PPRAPKLVEEKVASET---SPLPLKID-GAEEDPKSGSP 759
           P           PP++P+ + +  +SE+   SP P K+   A   P+S  P
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKP 443



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 33/146 (22%), Positives = 55/146 (37%), Gaps = 7/146 (4%)

Query: 426  SGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSH----QPLTRSLSEKNRCDQF 481
            S DS    L  +       +P  +  P E +   EG+P      +   RS S  +     
Sbjct: 2560 SSDSEGSSLPVQPEVALKRVPSPTPAPKEAV--REGRPPEPTPAKRKRRSSSSSSSSSSS 2617

Query: 482  RGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAK 541
              S  S  ++S      +  ++  SS ++  P P  P  +A+ +       PP   RS  
Sbjct: 2618 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRS 2677

Query: 542  PLSTSPSI-PPRTVKPARQQTRSPSP 566
            P     S+   R++  +  + R PSP
Sbjct: 2678 PRKPIDSLRDSRSLSYSPVERRRPSP 2703


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 92/354 (25%), Positives = 122/354 (34%), Gaps = 52/354 (14%)

Query: 424 QDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRG 483
           Q S DSGS      +SE+    P +S +   E+    G+      +RS S   R  Q   
Sbjct: 491 QSSSDSGSS----SSSEDER--PKRSHVKNGEV----GRRRRHSPSRSASPSPRKRQKET 540

Query: 484 SVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPR----S 539
           S R +   SP P P         +     P P PP         R    P  PPR    S
Sbjct: 541 SPRGRRRRSPSPPP---------TRRRRSPSPAPPP--------RRRRTPTPPPRRRTPS 583

Query: 540 AKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNR 599
             P   SPS  PR   P  Q+  SPSP     ++            P      S  P  R
Sbjct: 584 PPPRRRSPS--PRRYSPPIQRRYSPSPPPKRRTA-------SPPPPPKRRASPSPPPKRR 634

Query: 600 VKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQ-TRSDFLLDPSRSYS-YPRQKTP 657
           V       +    SP  +  S  LS   H  G+S S+ TR      P++ +S  PR + P
Sbjct: 635 VSHSPPPKQR--SSPVTKRRSPSLS-SKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691

Query: 658 GTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCP------KSASYSLESTDVKSLA 711
            T     P               SP T      VS  P      K+AS S +S    S +
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPI-RRVSRTPEPKKIKKAASPSPQSVRRVSSS 750

Query: 712 AGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSEDQ 765
             V+         PP  P  V+ +  S      + +  A+    S SP  + DQ
Sbjct: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ 804



 Score = 34.7 bits (78), Expect = 0.40
 Identities = 68/325 (20%), Positives = 116/325 (35%), Gaps = 44/325 (13%)

Query: 462 KPSHQPLTRSLSEKNRCDQFRGSVRSKC----ATSPLPIPGTLGAAVKSSDTALPPPPVP 517
           + S  P  R  S   R ++ R   RS      + SP P P       K     LP P V 
Sbjct: 175 RKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK-----KEKTPELPEPSVK 229

Query: 518 PKSEAVREECR---LLNAP----------PVPPRSAKPLSTSPSIPPRTVKPARQQTRSP 564
            K  +V+E      +L  P          P P +++K         PR+   ++ ++R+ 
Sbjct: 230 VKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTR 289

Query: 565 SPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSP-----FGSPSAEAV 619
           S + S+      +       +P         P  R +T    +  P       SP     
Sbjct: 290 SRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRR 349

Query: 620 SSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASP 679
            S  S     S +S S++RS     P R+ S PR+    +P  + P             P
Sbjct: 350 RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP--------RRRHRP 401

Query: 680 TSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASE 739
           + P T    +  S  P+ ++ + +S    S++ G T    +         K  E++ +  
Sbjct: 402 SPPATPPPKTRHSPTPQQSNRTRKSR--VSVSPGRTSGKVT-------KHKGTEKRESPS 452

Query: 740 TSPLPLKIDGAEEDPKSGSPDLSED 764
            +P P K++ +E +   G    + D
Sbjct: 453 PAPKPRKVELSESEEDKGGKMAAAD 477



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 36/164 (21%), Positives = 60/164 (36%), Gaps = 3/164 (1%)

Query: 506 SSDTALPPPPVPPK-SEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRT-VKPARQQT-R 562
           SS  +  PP  PPK + +   + R L+    PPR     S   + PP+T   P  QQ+ R
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422

Query: 563 SPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSR 622
           +    +S         VTK        +P       +V+    +        +A++V  R
Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482

Query: 623 LSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPA 666
             +      +S     S    D     S+ +    G  +R+ P+
Sbjct: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 60/267 (22%), Positives = 90/267 (33%), Gaps = 27/267 (10%)

Query: 488  KCATSPLPIPGTLGAAVKSSDTALPPP--PVPPKSEAVREECRLLNAPPV------PPRS 539
            KC T+P P P T  +   +S T LPP   P PP +           +PP+      PP +
Sbjct: 1394 KCITTPSP-PTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 540  --AKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPC 597
              + P+ST+ + PP T       T +PSP  +  S       T T T P  +TP      
Sbjct: 1453 TPSPPISTTTTPPPTTT--PSPPTTTPSPPTTTPSPP----TTTTTTPPPTTTPSPPTTT 1506

Query: 598  NRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP 657
                  S     P  +PS    ++    P      + S   +  +  P+ + + P   TP
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPT----TTPSPPTTTPITPPTSTTTLPPTTTP 1562

Query: 658  GTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQ 717
              P      P          +P+ P T   S            +  S    +        
Sbjct: 1563 SPPPTTTTTP------PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616

Query: 718  STSCPALPPRAPKLVEEKVASETSPLP 744
            + S P   P  P      +   T+P P
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSP 1643



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 54/231 (23%), Positives = 84/231 (36%), Gaps = 26/231 (11%)

Query: 459  EEGKPSHQPLT--RSLSEKNRCDQFRGSVRSKCATSPLP----IPGTLGAAVKSSDTALP 512
            + G P+H        L+  N   +      S+  +SPL     +  TL  A++ + TA P
Sbjct: 4194 QTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPP 4253

Query: 513  PPPVPPKSEA----VREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTL 568
              P  P + +    +        +PP  P       +S +  P TV+       +P+PT 
Sbjct: 4254 STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPT- 4312

Query: 569  SYYSSGLHNIVTKTDTNPSESTPVSCY--------PCNRVKTDSVDLKSPFGSPSAEAVS 620
                    +I+  T   P  S+ + C         P   V   +      F + S     
Sbjct: 4313 ---PLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTL 4369

Query: 621  SRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFD 671
               +W +  S  S + T S     PS+  S P + TPGT    CP   DFD
Sbjct: 4370 EFYNW-SCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECP---DFD 4416



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 57/268 (21%), Positives = 85/268 (31%), Gaps = 39/268 (14%)

Query: 495  PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTV 554
            P P T   +  ++ T  PPP   P             +PP       P ST+   P  T 
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTP-------------SPPTTTPITPPASTTTLPPTTTP 1523

Query: 555  KPARQQTRSPSPTLSYYSSGLHNIV--TKTDTNPSESTPVSCYPCNRVKTDSVDLKSP-- 610
             P    T +P PT +        I   T T T P  +TP S  P            SP  
Sbjct: 1524 SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP-SPPPTTTTTPPPTTTPSPPT 1582

Query: 611  FGSPSAEAVSSRLSWPNHYSG------------ASESQTRSDFLLDPSRSYSYPRQKTPG 658
              +PS   +++    P                  + S   +  +  P+ + + P   TP 
Sbjct: 1583 TTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642

Query: 659  TP--KRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTK 716
             P      P P          +P+ P+T   +   +  P S   +  S          T 
Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPP-------TTT 1695

Query: 717  QSTSCPALPPRAPKLVEEKVASETSPLP 744
             +T  P   P +P       +S T+P P
Sbjct: 1696 MTTPSPTTTPSSPITTTTTPSSTTTPSP 1723



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 55/260 (21%), Positives = 85/260 (32%), Gaps = 48/260 (18%)

Query: 491  TSPLPIPGTLGAAVKSSDTALPPP---PVPPKSEAVREECRLLNAPPVPPRSAKPLSTSP 547
            TS   +P T   +   + T  PPP   P PP +            PP P  +  P +T+ 
Sbjct: 1551 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP-PTTTPSPPTTTT 1609

Query: 548  SIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDL 607
            + PP T  P+   T   +P             T T T P  +TP S  P           
Sbjct: 1610 TTPPPTTTPSPPTTTPITPP------------TSTTTLPPTTTP-SPPPTTTTTPPPTTT 1656

Query: 608  KSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAP 667
             SP  + +     +  + P                  P+ + S P   TP  P      P
Sbjct: 1657 PSPPTTTTPSPPITTTTTP-----------------PPTTTPSSPITTTPSPPTTTMTTP 1699

Query: 668  FDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPR 727
                      +P+SP+T   + S +  P     ++ +    +  +  T   T+ P     
Sbjct: 1700 ------SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTS 1753

Query: 728  APKLVEEKVASETSPLPLKI 747
            +P          T+PLP  I
Sbjct: 1754 SP--------LTTTPLPPSI 1765



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 47/228 (20%), Positives = 75/228 (32%), Gaps = 24/228 (10%)

Query: 525  EECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDT 584
            ++C    +PP    S  P ST+   P  T  P    T +P PT +              T
Sbjct: 1393 DKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452

Query: 585  NPSE--STPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFL 642
             PS   ST  +  P       +     P  +PS    ++    P      + S   +  +
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPT----TTPSPPTTTPI 1508

Query: 643  LDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSL 702
              P+ + + P   TP  P      P          +P+ P T   +      P +++ +L
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTP------PPTTTPSPPTTTPIT------PPTSTTTL 1556

Query: 703  ESTDVKS--LAAGVTKQSTSCPALP----PRAPKLVEEKVASETSPLP 744
              T   S       T   T+ P+ P    P  P +        T+P P
Sbjct: 1557 PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP 1604



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 45/190 (23%), Positives = 72/190 (37%), Gaps = 11/190 (5%)

Query: 485  VRSKCATSPLPIP-GT---LGAAVKSSDTALPPP-PVPPKSEAVREECRLLNAPPVP-PR 538
            + +    +P P P GT       + ++ T  P P P   ++             P P P 
Sbjct: 4109 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4168

Query: 539  SAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCN 598
              +  +T+P     TV P    T + +   ++ S+     +T ++  P  STP +    +
Sbjct: 4169 GTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTS 4228

Query: 599  RVKTDSVDLKSPFGSPSAEAVSSR-LSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP 657
               T+S  L S    P+ E  S+   S P   +  S   T S     PS + S P   T 
Sbjct: 4229 SPLTESTTLLSTL-PPAIEMTSTAPPSTPTAPTTTSGGHTLSP---PPSTTTSPPGTPTR 4284

Query: 658  GTPKRNCPAP 667
            GT   +  AP
Sbjct: 4285 GTTTGSSSAP 4294



 Score = 30.4 bits (67), Expect = 7.5
 Identities = 57/283 (20%), Positives = 96/283 (33%), Gaps = 34/283 (12%)

Query: 485  VRSKCATSPLPIP-GT---LGAAVKSSDTALPPP-PVPPKSEAVREECRLLNAPPVP-PR 538
            + +    +P P P GT       + ++ T  P P P   ++             P P P 
Sbjct: 4040 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4099

Query: 539  SAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYS-----------SGLHNIVTKTDTNPS 587
              +  +T+P     TV P    T + +PT +  +           +G     T   T  +
Sbjct: 4100 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4159

Query: 588  ESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGA------SESQTRSDF 641
              TP       +  T +    +   +P+     ++   P H S A      + +      
Sbjct: 4160 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESS 4219

Query: 642  LLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYS 701
                SRS S P  ++  T     P   +       ++PT+P T     ++S  P S + S
Sbjct: 4220 TPQTSRSTSSPLTEST-TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSP-PPSTTTS 4277

Query: 702  LESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLP 744
               T  +    G T  S+S P      P  V+    S  +P P
Sbjct: 4278 PPGTPTR----GTTTGSSSAP-----TPSTVQTTTTSAWTPTP 4311


>gi|154090979 hypothetical protein LOC57481 [Homo sapiens]
          Length = 1709

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 107/459 (23%), Positives = 165/459 (35%), Gaps = 112/459 (24%)

Query: 448  KSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQ--FRGSVRSKCATSPLPIP-------- 497
            + +LP        GKP +Q    S S     +Q  F   + S+C + P+  P        
Sbjct: 870  EEDLPLRHPAQALGKPKNQQEVSSASNNTPEEQNDFMQQLPSRCPSQPIMNPTVQQQVPT 929

Query: 498  GTLGAAVKSSDTALPPPP-----------------VPPKSEAVREECRLLNAPPVPPRSA 540
             ++G ++K SD+  P PP                   PKS AV E    ++  P+PP+  
Sbjct: 930  SSVGTSIKQSDSVEPIPPRHPFQPWVNPKVEQEVSSSPKSMAVEES---ISMKPLPPK-- 984

Query: 541  KPLSTSPSIPPRTVKP--------ARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPV 592
              L   P + P+  +         A ++  S  P L  YS    ++        SEST V
Sbjct: 985  --LLCQPLMNPKVQQNMFSGSEDIAVERVISVEPLLPRYSP--QSLTDPQIRQISESTAV 1040

Query: 593  S-------------CYPCNRVK-TDSVDLKSPFGSPSAEAVSSRLSWP---------NHY 629
                            P  R K  DS+   + + SP A   S   S P            
Sbjct: 1041 EEGTYVEPLPPRCLSQPSERPKFLDSMSTSAEWSSPVAPTPSKYTSPPWVTPKFEELYQL 1100

Query: 630  SGASESQTRSDFLLDPSRSYSYPR---QKTPGTPKRNCPAPFDFDGCELLASPTSPVTAE 686
            S   ES T  +   D S+    PR   Q T G   +   + F+               A 
Sbjct: 1101 SAHPESTTVEE---DISKEQLLPRHLSQLTVGNKVQQLSSNFE--------------RAA 1143

Query: 687  FSSSVSGCPKSASYS---LESTDVKSLAAGVTK---QSTSCPALPPRAP-----KLVEEK 735
              + +SG P    Y+   L+ + V+ + + + K   + TS  +  PR P     K + ++
Sbjct: 1144 IEADISGSPLPPQYATQFLKRSKVQEMTSRLEKMAVEGTSNKSPIPRRPTQSFVKFMAQQ 1203

Query: 736  VASETSPLPLKIDGAEEDPKSGSPDLS----EDQYFVKKGMQD----IFSASYPFSSPLH 787
            + SE+S L    D A   P   S  LS    + Q F   G  +    I S   P   PL 
Sbjct: 1204 IFSESSALKRGSDVAPLPPNLPSKSLSKPEVKHQVFSDSGSANPKGGISSKMLPMKHPLQ 1263

Query: 788  LQLAPR------SCGDGSPWQPPADLSGLSIEEVSKSLR 820
                P       S  + +P +  +    LS  ++S++LR
Sbjct: 1264 SLGRPEDPQKVFSYSERAPGKCSSFKEQLSPRQLSQALR 1302


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 67/306 (21%), Positives = 107/306 (34%), Gaps = 46/306 (15%)

Query: 422  PYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQF 481
            P  +S ++ S     E +      PG+   P   +  +   P      R+LS        
Sbjct: 895  PVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSM-PDSTTPVVSSEARTLSATPVDTST 953

Query: 482  RGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAV-REECRLLNAPPVPPRSA 540
              +  ++  +SP    GT       S+   P    P     V   E   L+  PV   + 
Sbjct: 954  PVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTP 1013

Query: 541  KPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRV 600
               ST  S PP    P  + T  P+ T S  S+ L  +       P  +T V+    + +
Sbjct: 1014 LTTSTEASSPP----PTAEGTSMPTSTPSEGSTPLTRM-------PVSTTMVASSETSTL 1062

Query: 601  KTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTP 660
             T   D  +P  +               YS AS S T +D    P+ +YS        TP
Sbjct: 1063 STTPADTSTPVTT---------------YSQASSSSTTADGTSMPTSTYS-----EGSTP 1102

Query: 661  KRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTS 720
              + P              T  V +  +S++S  P   S  + +T  ++ ++  T + TS
Sbjct: 1103 LTSVPV------------STRLVVSSEASTLSTTPVDTSIPV-TTSTEASSSPTTAEGTS 1149

Query: 721  CPALPP 726
             P  PP
Sbjct: 1150 IPTSPP 1155



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 63/268 (23%), Positives = 99/268 (36%), Gaps = 31/268 (11%)

Query: 464  SHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAV 523
            S  P+  S+      +       +K  + P+  P    + V +S T++    +P  S   
Sbjct: 2595 STTPVDTSIPVTTSTETSSSPTTAKDTSMPISTP----SEVSTSLTSILVSTMPVASS-- 2648

Query: 524  REECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTD 583
              E   L+  PV  R+    ST  S  P T + +   T +P       S+ L NI+  T 
Sbjct: 2649 --EASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGER----STPLTNILVSTT 2702

Query: 584  TNP-SESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFL 642
                SE++ +S  P +     +   ++     +AE  S R+S P      S+  T    +
Sbjct: 2703 LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTP------SDGSTPLTSI 2756

Query: 643  LDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSL 702
            L  +   +     T  T   +   P          + +SP TAE +S  +  P   S  L
Sbjct: 2757 LVSTLPVASSEASTVSTTAVDTSIPVTTS----TEASSSPTTAEVTSMPTSTPSETSTPL 2812

Query: 703  ES-----TDVKSLAAG---VTKQSTSCP 722
             S     T V S  AG    T   TS P
Sbjct: 2813 TSMPVNHTPVASSEAGTLSTTPVDTSTP 2840



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 66/279 (23%), Positives = 100/279 (35%), Gaps = 18/279 (6%)

Query: 487 SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVR-EECRLLNAPPVPPRSAKPLST 545
           ++ ++SP    GT       ++ + P    P  +  V   E   L+  PV   +    ST
Sbjct: 310 TEASSSPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTST 369

Query: 546 SPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTD-TNPSESTPVSCYPCNRVKTDS 604
            PS  P T +     T     TLS  S+ L N+   T     SE++  S  P +  KT  
Sbjct: 370 EPSSLPTTAEATSMLTS----TLSEGSTPLTNMPVSTILVASSEASTTSTIPVDS-KTFV 424

Query: 605 VDLKSPFGSPS-AEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRN 663
                   SP+ AE  S   S P+  S    S   S   +  S + +     TP   K  
Sbjct: 425 TTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNL--STTPVDSKTQ 482

Query: 664 CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPA 723
                +        + +SP TAE +S  +  P   S  L S  V ++    ++ ST    
Sbjct: 483 VTTSTE--------ASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSEASTLSTT 534

Query: 724 LPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLS 762
               +  +     AS +S  P         P  GS  L+
Sbjct: 535 PVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLT 573



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 67/276 (24%), Positives = 101/276 (36%), Gaps = 28/276 (10%)

Query: 484  SVRSKCATSPLPI--PGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPR--- 538
            S  S  +TSP+    P T  A   SS T      +P  + +  E   LL + PV      
Sbjct: 1234 SEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTS--EGSTLLTSIPVSTTLVT 1291

Query: 539  --SAKPLSTSPSIPPRTVKPARQQTRSPSPT------LSYYSSGLHNIVTKTDTNPSEST 590
               A  L T+P      V  + + + SP+P        S YS G     T   + P  +T
Sbjct: 1292 SPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGR----TPLTSIPVNTT 1347

Query: 591  PVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSY- 649
             V+    + + T  VD  +P  + S EA SS    P    G S   +       P  S  
Sbjct: 1348 LVASSAISILSTTPVDNSTPV-TTSTEACSS----PTTSEGTSMPNSNPSEGTTPLTSIP 1402

Query: 650  --SYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDV 707
              + P   +  +     P      G     + +SP TAE  S  +  P      L+S  V
Sbjct: 1403 VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPV 1462

Query: 708  KSLAAGVTKQST-SCPALPPRAPKLVEEKVASETSP 742
             +     ++ ST S   +   +P +    V+S  +P
Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTP 1498



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 91/395 (23%), Positives = 141/395 (35%), Gaps = 43/395 (10%)

Query: 484  SVRSKCATSPLPI--PGTLGAAVKSSDTALPPPPV---PPKSEAVREECRLLNAPPVPPR 538
            S  S  +T+P+    P T  A   SS T      +    P   +      L++  PV   
Sbjct: 2707 SEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASS 2766

Query: 539  SAKPLSTSP---SIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTN----PSESTP 591
             A  +ST+    SIP  T   A     S SPT +  +S   +  ++T T     P   TP
Sbjct: 2767 EASTVSTTAVDTSIPVTTSTEA-----SSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTP 2821

Query: 592  VSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPN---HYSGASESQTRSDFLLDPSRS 648
            V+      + T  VD  +P  + S +A SS  +        S ASE  T    LL     
Sbjct: 2822 VASSEAGTLSTTPVDTSTPV-TTSTKASSSPTTAEGIVVPISTASEGST----LLTSIPV 2876

Query: 649  YSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVK 708
             + P   +  +     P              +SP TAE +S     P   S  L S  V 
Sbjct: 2877 STTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVS 2936

Query: 709  SL-AAGVTKQSTSCPALPPRAPKLVEEKVAS-----ETSPLPLKIDGAEEDP-----KSG 757
            ++  AG    + S   +  R P     + +S     E + +P+   G    P      S 
Sbjct: 2937 TVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVST 2996

Query: 758  SPDLSEDQYFVKKGMQDIFSASYPFSSPLHLQLAPRSC-GDGSPWQPPADLSGLSIEEVS 816
             P  S +   + +   D    S P ++      +P +  G G P   P++     +  + 
Sbjct: 2997 MPVASSEASTLSRTPAD---TSTPVTTSTEASSSPTTAEGTGIPISTPSE-GSTPLTSIP 3052

Query: 817  KSLRFIGLSEDVISFFVTEKIDGNLLVQLTEEILS 851
             S   + + E   S   T  +D N  V  + E+ S
Sbjct: 3053 VSTTPVAIPE--ASTLSTTPVDSNSPVVTSTEVSS 3085



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 64/284 (22%), Positives = 100/284 (35%), Gaps = 28/284 (9%)

Query: 487  SKCATSPLPIPGTLGAAVKSSDTALPPPPVP-PKSEAVREECRLLNAPPVPPRSAKPLST 545
            S+ ++SP    GT       S+ + P   +    +  V  E   L+  PV   +    ST
Sbjct: 3316 SQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVTTST 3375

Query: 546  SPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSV 605
              S+ P T +     T SPS              T   + P  +TPV     N + T  V
Sbjct: 3376 EASLSPTTAEGTSIPTSSPSEG-----------TTPLASMPVSTTPVVSSEVNTLSTTPV 3424

Query: 606  D----LKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPK 661
            D    + +   + S+  ++   S P   S  SE  T    +   +   +     T  T  
Sbjct: 3425 DSNTLVTTSTEASSSPTIAEGTSLPT--STTSEGSTPLSIMPLSTTPVASSEASTLST-- 3480

Query: 662  RNCPAPFDFDGCELLASPT--SPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQST 719
                 P D       +SPT  SP TAE +S  +      S  L +  V +     ++ ST
Sbjct: 3481 ----TPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEAST 3536

Query: 720  SCPALPPRAPKLVEEKVASETSPLPLKIDGAE-EDPKSGSPDLS 762
                 P  +   V     + +SP  L++       P  GS  L+
Sbjct: 3537 -LSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLT 3579



 Score = 37.0 bits (84), Expect = 0.080
 Identities = 72/324 (22%), Positives = 110/324 (33%), Gaps = 63/324 (19%)

Query: 487  SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKS-EAVREECRLLNAPPVPPRSAKPLST 545
            ++  +SP    GT       S+ + P   +P  +   V  E   L+A PV   +    ST
Sbjct: 2196 TEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTPVTTST 2255

Query: 546  SPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVS-----CYPCNRV 600
              +  P T     + T  P+ TLS              T P  S PVS         + +
Sbjct: 2256 EATSSPTTA----EGTSIPTSTLS------------EGTTPLTSIPVSHTLVANSEVSTL 2299

Query: 601  KTDSVDLKSPFGS--------PSAEAVS-------------SRLSWPNHYSGASESQTRS 639
             T  VD  +PF +        P+AE  S             +R+        + E+ T S
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359

Query: 640  DFLLD---PSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLAS---PTSPVTAEFSSSVSG 693
                D   P  +YS            + P     +G   L S    T PV +  +S+ S 
Sbjct: 2360 TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHST 2419

Query: 694  CPKSASYSLESTDVKSLAAGVTKQSTSCPALPP-------------RAPKLVEEKVASET 740
             P   S  + +T  ++ ++  T + TS P  PP               P +  E     T
Sbjct: 2420 TPVDTSTPV-TTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLST 2478

Query: 741  SPLPLKIDGAEEDPKSGSPDLSED 764
            +P+            S SP  +ED
Sbjct: 2479 TPVDTSTPMTTSTEASSSPTTAED 2502



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 62/245 (25%), Positives = 91/245 (37%), Gaps = 32/245 (13%)

Query: 534  PVPPRSAKPLSTSP---SIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSEST 590
            PV   +   LST+P   S P  T   AR      SPT S  +S + N      T P  S 
Sbjct: 1701 PVASSAISTLSTTPVDNSTPVTTSTEARS-----SPTTSEGTS-MPNSTPSEGTTPLTSI 1754

Query: 591  PVSCYP-----CNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDP 645
            PVS  P      + +    +D  +P  + S EA SS    P    G S   +     + P
Sbjct: 1755 PVSTTPVLSSEASTLSATPIDTSTPV-TTSTEATSS----PTTAEGTSIPTSTLSEGMTP 1809

Query: 646  SRSYSYPR---QKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSL 702
              S          +  +     P   +       A  +SP  AE +S  +  P   S +L
Sbjct: 1810 LTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTAL 1869

Query: 703  ESTDVK--SLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAE---EDPKSG 757
             S  V   ++A+  T   ++ PA+    P     +V+S     P   DG+      P+ G
Sbjct: 1870 TSIPVSTTTVASSETNTLSTTPAV-TSTPVTTYAQVSSS----PTTADGSSMPTSTPREG 1924

Query: 758  SPDLS 762
             P L+
Sbjct: 1925 RPPLT 1929



 Score = 35.0 bits (79), Expect = 0.30
 Identities = 62/261 (23%), Positives = 90/261 (34%), Gaps = 28/261 (10%)

Query: 509  TALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPTL 568
            T L   PV  K  A   E   L+  PV        ST  S  P T K     T  P  T 
Sbjct: 2574 TPLRSMPVSTKPLA-SSEASTLSTTPVDTSIPVTTSTETSSSPTTAK----DTSMPISTP 2628

Query: 569  SYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKS----PFGSPSAEAVSSRLS 624
            S  S+ L +I+  T        PV+    + + T  VD ++      G+ S+   +   S
Sbjct: 2629 SEVSTSLTSILVST-------MPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSS 2681

Query: 625  WPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVT 684
             P    G  E  T    +L  +   +     T  T   +   P          + +SP T
Sbjct: 2682 MPTSTPG--ERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSA----EASSSPTT 2735

Query: 685  AEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQST-SCPALPPRAPKLVEEKVAS----- 738
            AE +S     P   S  L S  V +L    ++ ST S  A+    P     + +S     
Sbjct: 2736 AEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTA 2795

Query: 739  ETSPLPLKIDGAEEDPKSGSP 759
            E + +P         P +  P
Sbjct: 2796 EVTSMPTSTPSETSTPLTSMP 2816



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 68/306 (22%), Positives = 106/306 (34%), Gaps = 32/306 (10%)

Query: 467  PLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREE 526
            PLTR          F  S  S    +    P T  +   SS T      +P  + +  E 
Sbjct: 2339 PLTRMPVSTTMVASFETSTLST-TPADTSTPVTTYSQAGSSPTTADDTSMPTSTYS--EG 2395

Query: 527  CRLLNAPPVP--PRSAKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDT 584
               L + PV   P  +   ST  + P  T  P    T + S   +   + +        T
Sbjct: 2396 STPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGT 2455

Query: 585  NPSESTPVSCYP-----CNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRS 639
             P  S PVS  P        + T  VD  +P  + S EA SS  +  +     S +   S
Sbjct: 2456 TPLASMPVSTTPVVSSEAGTLSTTPVDTSTPM-TTSTEASSSPTTAEDIVVPISTASEGS 2514

Query: 640  DFLLDPSRSYSYPRQKTP-GTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSA 698
              L       S P   TP  +P+ +  +    D    + + T   ++  S+  +  P S 
Sbjct: 2515 TLLT------SIPVSTTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTS- 2567

Query: 699  SYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPLPLKIDGAEEDPKSGS 758
            +YS  ST ++S+       ++S             E     T+P+   I        S S
Sbjct: 2568 TYSEGSTPLRSMPVSTKPLASS-------------EASTLSTTPVDTSIPVTTSTETSSS 2614

Query: 759  PDLSED 764
            P  ++D
Sbjct: 2615 PTTAKD 2620



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 60/268 (22%), Positives = 95/268 (35%), Gaps = 35/268 (13%)

Query: 487  SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREEC-RLLNAPPVPPRSAKPLST 545
            ++ ++SP P  GT       S+ + P   VP  +  V       L+  PV   +    ST
Sbjct: 3081 TEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTST 3140

Query: 546  SPSIPPRTVKPARQQTRSPSP---TLSYYSSGLHNIVTKTDTNPSE-----STPVSCYPC 597
                 P T +     T +PS     L+Y       +V+  D+  S      STPV+    
Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTE 3200

Query: 598  NRVKTDSVDLKSPFGSPSAEAVSSRLSWP--NHYSGASESQTRSDFLLDPSRSYSYPRQK 655
                T +     P  +PS E ++   S P  N    +SE+   S   +D +         
Sbjct: 3201 ATSSTTAEGTSIPTSTPS-EGMTPLTSVPVSNTPVASSEASILSTTPVDSN--------- 3250

Query: 656  TPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVT 715
            TP T                  + +SP TAE +S  +  P   S  L S  V +     +
Sbjct: 3251 TPLTTSTE--------------ASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASS 3296

Query: 716  KQSTSCPALPPRAPKLVEEKVASETSPL 743
            + ST        +  +     AS + P+
Sbjct: 3297 ETSTLSTTPADTSTPVTTYSQASSSPPI 3324



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 59/276 (21%), Positives = 97/276 (35%), Gaps = 22/276 (7%)

Query: 487 SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVRE-ECRLLNAPPVPPRSAKPLST 545
           ++  +S     GT       ++ + P   +P  +  V   E   L+  PV   +    ST
Sbjct: 664 TEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTTST 723

Query: 546 SPSIPPRTVKPARQQTRSPSP--------------TLSYYSSGLHNIVTKTDTNPSESTP 591
             S  P T   A   T +PS                 S  +S L      T T+ + ST 
Sbjct: 724 EASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTE 783

Query: 592 VSCYPCNRVKTDSVDLKSPF-GSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYS 650
            SC P     T S+ + +P  GSP   ++   ++       ++ S T  D     + S  
Sbjct: 784 ASCSPTTTEGT-SMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTE 842

Query: 651 YPRQKTPGTPKRNCPAPFDFDGCELLASP--TSPVTAEFSSSVSGCPKSASYSL-ESTDV 707
                TP        + +      L + P  T+ V     S++S  P   S  +  ST+ 
Sbjct: 843 VSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEA 902

Query: 708 KSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSPL 743
           +S  +  T + TS P   P         +   T+P+
Sbjct: 903 RS--SPTTSEGTSMPTSTPGEGSTPLTSMPDSTTPV 936



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 36/147 (24%), Positives = 56/147 (38%), Gaps = 9/147 (6%)

Query: 487  SKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSE-AVREECRLLNAPPVPPRSAKPLST 545
            S+ ++SP    GT       S+ + P   +P  +   V  E   L+  PV   +    ST
Sbjct: 1961 SQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTST 2020

Query: 546  SPSIPPRTVKPARQQTRSPSPTLSYYSS--GLHNIVTKTDTNPSESTPVSCYPCNRVKTD 603
              S  P T      QT +PS   +  +       +V  ++ N   +TPV        KT 
Sbjct: 2021 EGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDS------KTQ 2074

Query: 604  SVDLKSPFGSPSAEAVSSRLSWPNHYS 630
              +      S +AE  S  +S P+  S
Sbjct: 2075 VTNSTEASSSATAEGSSMTISAPSEGS 2101


>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 493 PLPIPGTLG-AAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPP 551
           P P+P  L  +++++S T+ PPPPVPP           L AP VPP  A PL  +P +  
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPP---PPATALQAPAVPPPPA-PLQIAPGVLH 383

Query: 552 RTVKPARQQTRSPSPTLS 569
               P       PSP ++
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 497 PGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAPPVPPRSAKPLST--SPSIPP 551
           P T    V  S T  PPPP  P    + ++R        PPVPP    P +   +P++PP
Sbjct: 311 PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 14/104 (13%)

Query: 489 CATSPL-PIPGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAP----PVPPRSA 540
           C T P+ P+P      V+      PPPP+PP   +  +      L + P    P P  + 
Sbjct: 407 CETVPVHPLPQ---GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 541 KP-LSTSPSIPPRTVKPARQQTRSPS--PTLSYYSSGLHNIVTK 581
            P +   P  PP  V PA +  R PS  P +S   S L   + K
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRK 507


>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 493 PLPIPGTLG-AAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPP 551
           P P+P  L  +++++S T+ PPPPVPP           L AP VPP  A PL  +P +  
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPP---PPATALQAPAVPPPPA-PLQIAPGVLH 383

Query: 552 RTVKPARQQTRSPSPTLS 569
               P       PSP ++
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 497 PGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAPPVPPRSAKPLST--SPSIPP 551
           P T    V  S T  PPPP  P    + ++R        PPVPP    P +   +P++PP
Sbjct: 311 PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 14/104 (13%)

Query: 489 CATSPL-PIPGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAP----PVPPRSA 540
           C T P+ P+P      V+      PPPP+PP   +  +      L + P    P P  + 
Sbjct: 407 CETVPVHPLPQ---GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 541 KP-LSTSPSIPPRTVKPARQQTRSPS--PTLSYYSSGLHNIVTK 581
            P +   P  PP  V PA +  R PS  P +S   S L   + K
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRK 507


>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 493 PLPIPGTLG-AAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPP 551
           P P+P  L  +++++S T+ PPPPVPP           L AP VPP  A PL  +P +  
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPP---PPATALQAPAVPPPPA-PLQIAPGVLH 383

Query: 552 RTVKPARQQTRSPSPTLS 569
               P       PSP ++
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 497 PGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAPPVPPRSAKPLST--SPSIPP 551
           P T    V  S T  PPPP  P    + ++R        PPVPP    P +   +P++PP
Sbjct: 311 PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 14/104 (13%)

Query: 489 CATSPL-PIPGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAP----PVPPRSA 540
           C T P+ P+P      V+      PPPP+PP   +  +      L + P    P P  + 
Sbjct: 407 CETVPVHPLPQ---GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 541 KP-LSTSPSIPPRTVKPARQQTRSPS--PTLSYYSSGLHNIVTK 581
            P +   P  PP  V PA +  R PS  P +S   S L   + K
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRK 507


>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
           sapiens]
          Length = 559

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 5/78 (6%)

Query: 493 PLPIPGTLG-AAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPP 551
           P P+P  L  +++++S T+ PPPPVPP           L AP VPP  A PL  +P +  
Sbjct: 328 PPPLPSALSTSSLRASMTSTPPPPVPPPPP---PPATALQAPAVPPPPA-PLQIAPGVLH 383

Query: 552 RTVKPARQQTRSPSPTLS 569
               P       PSP ++
Sbjct: 384 PAPPPIAPPLVQPSPPVA 401



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 497 PGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAPPVPPRSAKPLST--SPSIPP 551
           P T    V  S T  PPPP  P    + ++R        PPVPP    P +   +P++PP
Sbjct: 311 PATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATALQAPAVPP 370



 Score = 30.0 bits (66), Expect = 9.8
 Identities = 31/104 (29%), Positives = 43/104 (41%), Gaps = 14/104 (13%)

Query: 489 CATSPL-PIPGTLGAAVKSSDTALPPPPVPP---KSEAVREECRLLNAP----PVPPRSA 540
           C T P+ P+P      V+      PPPP+PP   +  +      L + P    P P  + 
Sbjct: 407 CETVPVHPLPQ---GEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAP 463

Query: 541 KP-LSTSPSIPPRTVKPARQQTRSPS--PTLSYYSSGLHNIVTK 581
            P +   P  PP  V PA +  R PS  P +S   S L   + K
Sbjct: 464 GPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLLEAIRK 507


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 19/128 (14%)

Query: 513  PPPVPPKSEAVREECRLLN--APPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPT-LS 569
            PPPVPPK  ++       +   P  PP + KP+   P +P  T KP       P PT LS
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV--IPQLPTTTQKPT---DIHPKPTGLS 2537

Query: 570  YYSSGLHNIVTKTDTN-PSESTPVSCYP------CNRVKTDS---VDLKSPFGSPSAEAV 619
              SS   N+VT  D   PS ++P+S +        ++  T++   + L S  G+P+  + 
Sbjct: 2538 LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597

Query: 620  SSRL-SWP 626
            S  + SWP
Sbjct: 2598 SQAITSWP 2605



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 76/349 (21%), Positives = 124/349 (35%), Gaps = 54/349 (15%)

Query: 387 SVCVYGNNLHGNSE-----VNLHGCRDLGGDWAPFPHDILPYQDSGDSGSDYLFPEASEE 441
           S+C +  N H         +N    R LGGD AP P    P   +    +     ++S +
Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 442 SAGI-PGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTL 500
                P K   P ++L          PL +  +         GS  +K    P       
Sbjct: 679 PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT-------LHGSPSAKAKQPP------- 724

Query: 501 GAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQ 560
               ++   + P PP  P   + +++  + +  P  P+  KP +   S    T KP    
Sbjct: 725 ----EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP---- 776

Query: 561 TRSPSPTLSYYSSGLHNIVTKTDT-NPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAV 619
              PS  +   +        KTD+  PS+S P            + +  SPF S +    
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP-----------PTGEKVSPFDSKAIPRP 824

Query: 620 SSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQ-KTPGTPKRNC-PAPFDFDGCELLA 677
           +S     +H   +SES+ +    +DP +    P++ +T  +PK +  P P          
Sbjct: 825 ASDSKIISHPGPSSESKGQKQ--VDPVQKKEEPKKAQTKMSPKPDAKPMP--------KG 874

Query: 678 SPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAG-VTKQSTSCPALP 725
           SPT P     +      P+ +    E +   SL  G +T    S P  P
Sbjct: 875 SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 75/336 (22%), Positives = 105/336 (31%), Gaps = 73/336 (21%)

Query: 490 ATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS- 548
           A  P   PG+     +   +  PPP  P  ++   ++      P   P SAKP +  PS 
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546

Query: 549 --------------------IPPRTVKPARQQTRSPS------PTLSYYSSGLH------ 576
                               + P TV P+ +Q  S        P  +     LH      
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 577 -NIVTKTDT--------NP----SESTPVSCYPCNRVKTDSVDLKSPFGSP--------- 614
            N  T+  T        NP    +E     C  C   +    DL     SP         
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666

Query: 615 -SAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP---GTPKRNCPAPFDF 670
            +  AVS     P   S   ++  + D    P      P  K P   G+P      P + 
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726

Query: 671 DGCELLASPTSP-VTAEFSSS--VSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPR 727
           D     A P  P V +E   +      PK       +TD+ S ++  TK         P 
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK---------PD 777

Query: 728 APKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSE 763
            P    +  A E +  PLK D A+  P    P   E
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAK--PSQSFPPTGE 811



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 72/330 (21%), Positives = 109/330 (33%), Gaps = 57/330 (17%)

Query: 445 IPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPI-PGTLGAA 503
           +P  S+ P     +++  P   P  +   EK++    +   +    T PL   PGT+   
Sbjct: 298 LPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352

Query: 504 VKSSDTALPP-----PPVPPKSEAVREECRLLNAPPVPPRSAKP--LSTSPSIPPRTVKP 556
           V+   T  PP     P  PP  +   E+    +  P P   A+P  +  +P+  P   KP
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPS--SEQPGPKALAQPPGVGKTPAQQPGPAKP 410

Query: 557 ARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSA 616
             QQ  +P P                   P   +P                K+P   P  
Sbjct: 411 PTQQVGTPKPLAQ---------------QPGLQSPAKA---------PGPTKTPVQQPGP 446

Query: 617 EAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELL 676
             + ++ + P   S      T+    L P  +   P+Q  P  P    P           
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQL-PGPAKPPPQQPGPAKPPPQQPGS--------- 496

Query: 677 ASPTS--PVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
           A P S  P + +      G  K +     ST   S   G  K S   P+ P +       
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS-PAKPSAQQST 555

Query: 735 KVASET---SPL--PLKIDGAEEDPKSGSP 759
           K  S+T    PL  P     A++ P  G P
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 87/357 (24%), Positives = 121/357 (33%), Gaps = 93/357 (26%)

Query: 463  PSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEA 522
            PS  P   SL  K R   FR S     A  P P                PPPP PP    
Sbjct: 2377 PSGSPSVSSLPAKPR-PFFRSSSLDISAQPPPP----------------PPPPPPP---- 2415

Query: 523  VREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQT-RSPSPTLSYYSSGLHNIVTK 581
                      PP PP    P    P+ P  T+ P ++ T  SP  T    ++ L + VT 
Sbjct: 2416 ----------PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTT----ATPLFDAVTT 2461

Query: 582  TDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDF 641
             +T     +  +  P  R+ T +     P   P   ++ S L + +              
Sbjct: 2462 LETTAVLRS--NGLPVTRICTTA----PPPVPPKPSSIPSGLVFTHR------------- 2502

Query: 642  LLDPSRSYSYPRQKTPGTPKRNCPAPFDF----DGCEL---------------LASPTSP 682
              +PS+    P+   P  P      P D      G  L               L SPTSP
Sbjct: 2503 -PEPSKPPIAPKPVIPQLP-TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP 2560

Query: 683  VTAEFSSSVSGCPKSAS-----YSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVA 737
            ++   + S     KS +      +L S       +  ++  TS P   P    +  E V 
Sbjct: 2561 LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVF 2620

Query: 738  SETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASYPFSSPLHLQLAPRS 794
            S   P+      A E P      +S +Q F   G    FSA+ P ++P   Q AP S
Sbjct: 2621 SVVPPVT-----AVEIP------ISSEQTFYISGALQTFSAT-PVTAPSSFQAAPTS 2665


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 41/128 (32%), Positives = 61/128 (47%), Gaps = 19/128 (14%)

Query: 513  PPPVPPKSEAVREECRLLN--APPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPSPT-LS 569
            PPPVPPK  ++       +   P  PP + KP+   P +P  T KP       P PT LS
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPV--IPQLPTTTQKPT---DIHPKPTGLS 2537

Query: 570  YYSSGLHNIVTKTDTN-PSESTPVSCYP------CNRVKTDS---VDLKSPFGSPSAEAV 619
              SS   N+VT  D   PS ++P+S +        ++  T++   + L S  G+P+  + 
Sbjct: 2538 LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597

Query: 620  SSRL-SWP 626
            S  + SWP
Sbjct: 2598 SQAITSWP 2605



 Score = 38.5 bits (88), Expect = 0.027
 Identities = 76/349 (21%), Positives = 124/349 (35%), Gaps = 54/349 (15%)

Query: 387 SVCVYGNNLHGNSE-----VNLHGCRDLGGDWAPFPHDILPYQDSGDSGSDYLFPEASEE 441
           S+C +  N H         +N    R LGGD AP P    P   +    +     ++S +
Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ 678

Query: 442 SAGI-PGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTL 500
                P K   P ++L          PL +  +         GS  +K    P       
Sbjct: 679 PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT-------LHGSPSAKAKQPP------- 724

Query: 501 GAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQ 560
               ++   + P PP  P   + +++  + +  P  P+  KP +   S    T KP    
Sbjct: 725 ----EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP---- 776

Query: 561 TRSPSPTLSYYSSGLHNIVTKTDT-NPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAV 619
              PS  +   +        KTD+  PS+S P            + +  SPF S +    
Sbjct: 777 -DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFP-----------PTGEKVSPFDSKAIPRP 824

Query: 620 SSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQ-KTPGTPKRNC-PAPFDFDGCELLA 677
           +S     +H   +SES+ +    +DP +    P++ +T  +PK +  P P          
Sbjct: 825 ASDSKIISHPGPSSESKGQKQ--VDPVQKKEEPKKAQTKMSPKPDAKPMP--------KG 874

Query: 678 SPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAG-VTKQSTSCPALP 725
           SPT P     +      P+ +    E +   SL  G +T    S P  P
Sbjct: 875 SPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTP 923



 Score = 38.1 bits (87), Expect = 0.036
 Identities = 75/336 (22%), Positives = 105/336 (31%), Gaps = 73/336 (21%)

Query: 490 ATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPS- 548
           A  P   PG+     +   +  PPP  P  ++   ++      P   P SAKP +  PS 
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546

Query: 549 --------------------IPPRTVKPARQQTRSPS------PTLSYYSSGLH------ 576
                               + P TV P+ +Q  S        P  +     LH      
Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKAN 606

Query: 577 -NIVTKTDT--------NP----SESTPVSCYPCNRVKTDSVDLKSPFGSP--------- 614
            N  T+  T        NP    +E     C  C   +    DL     SP         
Sbjct: 607 FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPV 666

Query: 615 -SAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTP---GTPKRNCPAPFDF 670
            +  AVS     P   S   ++  + D    P      P  K P   G+P      P + 
Sbjct: 667 TTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA 726

Query: 671 DGCELLASPTSP-VTAEFSSS--VSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPR 727
           D     A P  P V +E   +      PK       +TD+ S ++  TK         P 
Sbjct: 727 DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTK---------PD 777

Query: 728 APKLVEEKVASETSPLPLKIDGAEEDPKSGSPDLSE 763
            P    +  A E +  PLK D A+  P    P   E
Sbjct: 778 IPSSKVQSQAEEKTTPPLKTDSAK--PSQSFPPTGE 811



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 72/330 (21%), Positives = 109/330 (33%), Gaps = 57/330 (17%)

Query: 445 IPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPI-PGTLGAA 503
           +P  S+ P     +++  P   P  +   EK++    +   +    T PL   PGT+   
Sbjct: 298 LPSPSKPP-----IQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPP 352

Query: 504 VKSSDTALPP-----PPVPPKSEAVREECRLLNAPPVPPRSAKP--LSTSPSIPPRTVKP 556
           V+   T  PP     P  PP  +   E+    +  P P   A+P  +  +P+  P   KP
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPS--SEQPGPKALAQPPGVGKTPAQQPGPAKP 410

Query: 557 ARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSA 616
             QQ  +P P                   P   +P                K+P   P  
Sbjct: 411 PTQQVGTPKPLAQ---------------QPGLQSPAKA---------PGPTKTPVQQPGP 446

Query: 617 EAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCPAPFDFDGCELL 676
             + ++ + P   S      T+    L P  +   P+Q  P  P    P           
Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQL-PGPAKPPPQQPGPAKPPPQQPGS--------- 496

Query: 677 ASPTS--PVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
           A P S  P + +      G  K +     ST   S   G  K S   P+ P +       
Sbjct: 497 AKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPS-PAKPSAQQST 555

Query: 735 KVASET---SPL--PLKIDGAEEDPKSGSP 759
           K  S+T    PL  P     A++ P  G P
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 87/357 (24%), Positives = 121/357 (33%), Gaps = 93/357 (26%)

Query: 463  PSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPVPPKSEA 522
            PS  P   SL  K R   FR S     A  P P                PPPP PP    
Sbjct: 2377 PSGSPSVSSLPAKPR-PFFRSSSLDISAQPPPP----------------PPPPPPP---- 2415

Query: 523  VREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQT-RSPSPTLSYYSSGLHNIVTK 581
                      PP PP    P    P+ P  T+ P ++ T  SP  T    ++ L + VT 
Sbjct: 2416 ----------PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTT----ATPLFDAVTT 2461

Query: 582  TDTNPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDF 641
             +T     +  +  P  R+ T +     P   P   ++ S L + +              
Sbjct: 2462 LETTAVLRS--NGLPVTRICTTA----PPPVPPKPSSIPSGLVFTHR------------- 2502

Query: 642  LLDPSRSYSYPRQKTPGTPKRNCPAPFDF----DGCEL---------------LASPTSP 682
              +PS+    P+   P  P      P D      G  L               L SPTSP
Sbjct: 2503 -PEPSKPPIAPKPVIPQLP-TTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP 2560

Query: 683  VTAEFSSSVSGCPKSAS-----YSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVA 737
            ++   + S     KS +      +L S       +  ++  TS P   P    +  E V 
Sbjct: 2561 LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVF 2620

Query: 738  SETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSASYPFSSPLHLQLAPRS 794
            S   P+      A E P      +S +Q F   G    FSA+ P ++P   Q AP S
Sbjct: 2621 SVVPPVT-----AVEIP------ISSEQTFYISGALQTFSAT-PVTAPSSFQAAPTS 2665


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 87/368 (23%), Positives = 122/368 (33%), Gaps = 67/368 (18%)

Query: 426 SGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSV 485
           S  SG+  L P+        PGK++ P  E              R  S ++       S+
Sbjct: 585 SSQSGTPTLPPKGLAGPPASPGKAQPPKPE--------------RVTSLRSPGASVSSSL 630

Query: 486 RSKCATSPLPIP----GTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRS-- 539
            S C++S  P P    G            +PP P  P            + PP  PRS  
Sbjct: 631 TSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAP---------FSPPPSKPRSPN 681

Query: 540 -AKPLSTSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCY-PC 597
            A P   +P++ P  V       +SP    +  +    + V   D +P  S P S + P 
Sbjct: 682 PAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPP 741

Query: 598 NRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSR----SYSYPR 653
              K   V +++P  S +AE      +WP     A E Q  S     P      S + P 
Sbjct: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE 801

Query: 654 QKTP-GTPKR-NCPAPFDFDGCELLAS--------PTSPVTAEFSSSVS----------- 692
              P G+P+  + PA        L           P  P  A  SS+             
Sbjct: 802 PAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPV 861

Query: 693 GCPKSASYSLESTD----VKSLAAGVTKQSTSC------PALPPRAP-KLVEEKVASETS 741
           GC K      E         SL   V  +S         PAL P AP K +   ++   S
Sbjct: 862 GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRAS 921

Query: 742 PLPLKIDG 749
           P+P    G
Sbjct: 922 PVPAPSSG 929


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 98/402 (24%), Positives = 144/402 (35%), Gaps = 75/402 (18%)

Query: 437 EASEESAGIPGKSELPYEELWLEEGKPSHQPLTR-SLSEKNRCDQFRGSVRSKCATSPLP 495
           + +E++  +PG           E   P   P  R  +  K R       + S  A  P P
Sbjct: 244 QLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTP 303

Query: 496 IPGTLGAAVKSSDTALPPPPVP-PKSEAVREEC------------RLLNAP-PVPPRSAK 541
            P       K+S++  P PP P P+S   +E              RL   P P P  + K
Sbjct: 304 APR------KASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPK 357

Query: 542 PLSTSPS---IPPRTVKPARQQTRSPSPTLSYYSSG--------LHNIVTKTDTNPSEST 590
           P   +P+    PP       +  + P+P     S G        + N  T+    PS + 
Sbjct: 358 PSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTA 417

Query: 591 PVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYS 650
            +   P N  + +  D +    +  + A S  L  P       ES  +S   L P   Y 
Sbjct: 418 SLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHP-------ESTPKS---LHP--WYG 465

Query: 651 YPRQKTPGTPKRNCPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSL 710
                +P T KR  PAP         A   SP+    S      P SA+ S  +  V+SL
Sbjct: 466 ITPTSSPKTKKR--PAP--------RAPSASPLALHASRLSHSEPPSATPS-PALSVESL 514

Query: 711 AAGVTKQSTSCPAL-PPRAPKLVEEKV--ASETSPLPLKIDGAEEDPKSGSPDLSEDQYF 767
           ++    Q+     L PP  PK   E    A  T   P+ +        S +  L+     
Sbjct: 515 SSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSL--------STNSSLASSGEL 566

Query: 768 VKKGMQDIFSASYPFSSPLHLQLAPRSCGDGSPWQPPADLSG 809
           V+  ++ +     P +SP    LAPR+ G   P QP    SG
Sbjct: 567 VEPRVEQM-----PQASP---GLAPRTRGSSGP-QPAKPCSG 599


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 69/265 (26%), Positives = 92/265 (34%), Gaps = 18/265 (6%)

Query: 545  TSPSIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDS 604
            TSP+  PR+      Q+ S SPT   YS       T    +P+        P     + S
Sbjct: 1596 TSPAYEPRSPGGYTPQSPSYSPTSPSYSP------TSPSYSPTSPNYSPTSPSYSPTSPS 1649

Query: 605  VDLKSPFGSPSAEAVSSRLSWPNHYSGASESQTRSDFLLDP-SRSYSYPRQKTPGTPKRN 663
                SP  SP++ + S        YS  S S + +     P S SYS        T    
Sbjct: 1650 YSPTSPSYSPTSPSYSPT---SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706

Query: 664  CPAPFDFDGCELLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTS--- 720
             P    +       SPTSP  +  S S S  P S SYS  S +    +   T  S S   
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYS--PTSPSYSPTSPNYSPTSPNYTPTSPSYSP 1764

Query: 721  -CPALPPRAPKLVEEKV-ASETSPLPLKIDGAEEDPKSGSPDLSEDQYFVKKGMQDIFSA 778
              P+  P +P         S TSP           P S S   S  +Y  +       S 
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSP-SYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSP 1823

Query: 779  SYPFSSPLHLQLAPRSCGDGSPWQP 803
            SY  SSP +   +P+       + P
Sbjct: 1824 SYSPSSPSYSPTSPKYTPTSPSYSP 1848


>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
          Length = 931

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 79/329 (24%), Positives = 121/329 (36%), Gaps = 58/329 (17%)

Query: 417 PHDILPYQDSGDSGSDYLFPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKN 476
           P  IL  ++   +GS  L P    E  G         ++  L+E     + LTR L +K 
Sbjct: 493 PLQILVKEEGPRAGSCCLSPGGRAELEGRD-------KDQMLQEKDKQIEALTRMLRQKQ 545

Query: 477 RC-DQFRGSV-RSKCATSPLPIPGTLGAAVKSSDTAL----------PPPPVPPKSEAVR 524
           +  ++ +  + + K A  P P P  LG  VK  ++            P  P  P   A  
Sbjct: 546 QLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPA 605

Query: 525 ----EECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRS-----PSPTLSYYSSGL 575
               + C +   PP      + L   P   P        Q  S       PTL   S+G 
Sbjct: 606 TNHIDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGT 665

Query: 576 HNIVTKTDTN---PSESTPVSCYPCNR------VKTDSVDLKSP----FGSPSA------ 616
           H ++T T+ N   P  S+     P ++        +  +DL+ P    FG+P++      
Sbjct: 666 HLVLTVTNKNADSPGLSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQPLFGTPTSLLKKEP 725

Query: 617 ----EAVSSRLSWPNHYSGASESQTRSDF--LLDPSRSYSYPRQKTPGTPKRNCPAPFDF 670
               EA+S +   P      S SQ   D   +L  S   S   ++ P  P +  P+P   
Sbjct: 726 PGYEEAMSQQ---PKQQENGSSSQQMDDLFDILIQSGEISADFKEPPSLPGKEKPSPKTV 782

Query: 671 DGCELLASPTSPVTAEFSSSVSGCPKSAS 699
            G  L A P+   +AE   +    P S S
Sbjct: 783 CGSPLAAQPSP--SAELPQAAPPPPGSPS 809


>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
            sapiens]
          Length = 2036

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 87/348 (25%), Positives = 122/348 (35%), Gaps = 54/348 (15%)

Query: 435  FPEASEESAGIPGKSELPYEELWLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPL 494
            +P +S+ +   PG +  P E       +PS  P T   +            RS+ +T+  
Sbjct: 1073 WPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLG------RSEESTTVH 1126

Query: 495  PIPGTLGAAV----KSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLS--TSPS 548
              PG  G A+     ++   +  P   P S    E   L  +      S K  +  +SP 
Sbjct: 1127 SSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPR 1186

Query: 549  IPPRTVKPA--------RQQTRSPS----------------PTLSYYSSGLHNIVTKTDT 584
             P  T+ PA         + T S S                P +S  S+  H+    TDT
Sbjct: 1187 SPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDT 1246

Query: 585  --NPSESTPVSCYPCNRVKTDSVDLKSPFGSPSAEAVSSRL--SWPNHYSGASESQTRSD 640
              +P  +T  S  P +     S         P     S  L  S P H S  S   T S 
Sbjct: 1247 TLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSP 1306

Query: 641  FLLDPSRSYSYPRQKTPGTPKRNCPAP------FDFDGCELLASPTSPVTAEFSSSVSGC 694
                  +  S   Q  P + K   PAP      F         SP+S  T  FS+S +  
Sbjct: 1307 AGSTTRQGESTTFQSWPSS-KDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTL 1365

Query: 695  PKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEEKVASETSP 742
             +S     EST V S  + V   +T  PA    +  LVEE  A  +SP
Sbjct: 1366 GRSE----ESTTVHS--SPVATATTPSPARSTTS-GLVEESTAYHSSP 1406



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 65/248 (26%), Positives = 97/248 (39%), Gaps = 23/248 (9%)

Query: 506 SSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTVKPARQQTRSPS 565
           S+DTAL P      S   +E     + P     +  P ST+ S            T SP 
Sbjct: 546 STDTALSPGSTTALSFG-QESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPR 604

Query: 566 PTLSYYSS---GLHNIVTKTDTNPSESTPVSCYPCNR---VKTDSVDLKSPFGSPSAEAV 619
            TLS  SS   GL    T   T+P+ +      P      V+  +   +SP  +P+    
Sbjct: 605 TTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFP 664

Query: 620 SSRLSWPNHYSGASESQTRSDFLLD-----PSRSYSYPRQKTPGTPKRNCPAPFDFDGCE 674
           +S  +     SG SE  T      D     PS ++S    +   T  R  P   +     
Sbjct: 665 ASSTT-----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEIT--T 717

Query: 675 LLASPTSPVTAEFSSSVSGCPKSASYSLESTDVKSLAAGVTKQSTSCPALPPRAPKLVEE 734
           L  S T+P  +E S++    P+S + +L    + SL  GV ++ST+  + P      V  
Sbjct: 718 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSL--GVGEESTTSRSQPGSTHSTVSP 775

Query: 735 KVASETSP 742
             AS T+P
Sbjct: 776 --ASTTTP 781


>gi|66932999 testis-specific protein kinase 1 [Homo sapiens]
          Length = 626

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/286 (24%), Positives = 99/286 (34%), Gaps = 66/286 (23%)

Query: 457 WLEEGKPSHQPLTRSLSEKNRCDQFRGSVRSKCATSPLPIPGTLGAAVKSSDTALPPPPV 516
           W+ E  P   PLTR+    N+    RG      AT P P P     +   SD  LPP P 
Sbjct: 313 WILEQLPEPAPLTRTALTHNQGSVARG---GPSATLPRPDP---RLSRSRSDLFLPPSPE 366

Query: 517 PPKS----------EAVREECR-----LLNAPPVP----------PRSAKPLSTSP---- 547
            P +           ++RE+ R     LL+ P  P          P +  PL T+P    
Sbjct: 367 SPPNWGDNLTRVNPFSLREDLRGGKIKLLDTPSKPVLPLVPPSPFPSTQLPLVTTPETLV 426

Query: 548 ----------SIPPRTVKPARQQTRSPSPTLSYYSSGLHNIVTKTDTN-------PSEST 590
                     S+P     P R +T  P P            +    ++       P+   
Sbjct: 427 QPGTPARRCRSLPSSPELPRRMETALPGPGPPAVGPSAEEKMECEGSSPEPEPPGPAPQL 486

Query: 591 PVSCYPCNRVKTDSVDLKSPF---------GSPSAEAVSSRLSWPNH-YSGASESQTRSD 640
           P++    N + T S     P+          +P A  V+S   W    ++ A  S  R+ 
Sbjct: 487 PLAVATDNFISTCS-SASQPWSPRSGPVLNNNPPAVVVNSPQGWAGEPWNRAQHSLPRAA 545

Query: 641 FL--LDPSRSYSYPRQKTPGTPKRN-CPAPFDFDGCELLASPTSPV 683
            L   +PS   S PR+   G P    C  PF F    +   PT  V
Sbjct: 546 ALERTEPSPPPSAPREPDEGLPCPGCCLGPFSFGFLSMCPRPTPAV 591


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 9/173 (5%)

Query: 495 PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTV 554
           P P TL  AVK    A P P  PP      +     +  P P  S KP + SPS P +  
Sbjct: 624 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHP-PSLSPKPPTRSPSPPTQHT 682

Query: 555 KPARQQTRSPSPTLS--YYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFG 612
                Q  +PS   +   YSS L  I  +   +P    P    P    K +S    +P  
Sbjct: 683 GQPPGQPSAPSQLSAPRRYSSSLSPI--QAPNHPPPQPPTQATPLMHTKPNSQGPPNPMA 740

Query: 613 SPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCP 665
            PS       L  P+H    + +   +  L   + S   P+    G P+   P
Sbjct: 741 LPSEHG----LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQP 789


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 46/173 (26%), Positives = 63/173 (36%), Gaps = 9/173 (5%)

Query: 495 PIPGTLGAAVKSSDTALPPPPVPPKSEAVREECRLLNAPPVPPRSAKPLSTSPSIPPRTV 554
           P P TL  AVK    A P P  PP      +     +  P P  S KP + SPS P +  
Sbjct: 546 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHP-PSLSPKPPTRSPSPPTQHT 604

Query: 555 KPARQQTRSPSPTLS--YYSSGLHNIVTKTDTNPSESTPVSCYPCNRVKTDSVDLKSPFG 612
                Q  +PS   +   YSS L  I  +   +P    P    P    K +S    +P  
Sbjct: 605 GQPPGQPSAPSQLSAPRRYSSSLSPI--QAPNHPPPQPPTQATPLMHTKPNSQGPPNPMA 662

Query: 613 SPSAEAVSSRLSWPNHYSGASESQTRSDFLLDPSRSYSYPRQKTPGTPKRNCP 665
            PS       L  P+H    + +   +  L   + S   P+    G P+   P
Sbjct: 663 LPSEHG----LEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQP 711


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,083,831
Number of Sequences: 37866
Number of extensions: 2112787
Number of successful extensions: 10744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 554
Number of HSP's that attempted gapping in prelim test: 8469
Number of HSP's gapped (non-prelim): 2020
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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