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Search of human proteins with 29171734
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29171734 eukaryotic translation initiation factor 2C, 2
[Homo sapiens]
(859 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo... 1762 0.0
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ... 1473 0.0
gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo... 1419 0.0
gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo... 1402 0.0
gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo... 1119 0.0
gi|66346725 piwi-like 1 [Homo sapiens] 168 2e-41
gi|221316711 piwi-like 4 [Homo sapiens] 168 2e-41
gi|153792298 piwi-like 3 [Homo sapiens] 156 7e-38
gi|209180418 piwi-like 2 [Homo sapiens] 148 2e-35
gi|24431985 piwi-like 2 [Homo sapiens] 148 2e-35
gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap... 50 1e-05
gi|11386183 WAS protein family, member 2 [Homo sapiens] 33 0.87
gi|156071470 hyperpolarization activated cyclic nucleotide-gated... 33 1.5
gi|7706687 Enah/Vasp-like [Homo sapiens] 33 1.5
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 33 1.5
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 32 1.9
gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens] 32 2.5
gi|146134388 YLP motif containing 1 [Homo sapiens] 32 2.5
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 32 3.3
gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo ... 32 3.3
gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo ... 32 3.3
gi|145309324 FH2 domain containing 1 [Homo sapiens] 32 3.3
gi|5729962 submaxillary gland androgen regulated protein 3 homol... 32 3.3
gi|22035556 transcription initiation factor IIIB isoform 1 [Homo... 31 4.3
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 31 5.6
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 31 5.6
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 31 5.6
gi|57863314 vacuolar protein sorting 37C [Homo sapiens] 31 5.6
gi|33286436 gametogenetin [Homo sapiens] 31 5.6
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 30 7.3
>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
sapiens]
Length = 859
Score = 1762 bits (4563), Expect = 0.0
Identities = 859/859 (100%), Positives = 859/859 (100%)
Query: 1 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD 60
MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD
Sbjct: 1 MYSGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELD 60
Query: 61 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP 120
IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP
Sbjct: 61 IKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLP 120
Query: 121 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS 180
GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS
Sbjct: 121 GEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRS 180
Query: 181 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF 240
FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF
Sbjct: 181 FFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDF 240
Query: 241 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES 300
KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES
Sbjct: 241 KSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQES 300
Query: 301 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ 360
GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ
Sbjct: 301 GQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQ 360
Query: 361 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY 420
TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY
Sbjct: 361 TSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILY 420
Query: 421 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD 480
GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD
Sbjct: 421 GGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRD 480
Query: 481 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL 540
AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL
Sbjct: 481 AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVL 540
Query: 541 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH 600
GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH
Sbjct: 541 GMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTH 600
Query: 601 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK 660
PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK
Sbjct: 601 PPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFK 660
Query: 661 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK 720
PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK
Sbjct: 661 PTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDK 720
Query: 721 NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ 780
NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ
Sbjct: 721 NERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQ 780
Query: 781 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ 840
ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ
Sbjct: 781 ILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQ 840
Query: 841 ALAKAVQVHQDTLRTMYFA 859
ALAKAVQVHQDTLRTMYFA
Sbjct: 841 ALAKAVQVHQDTLRTMYFA 859
>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
sapiens]
Length = 857
Score = 1473 bits (3814), Expect = 0.0
Identities = 711/857 (82%), Positives = 787/857 (91%), Gaps = 4/857 (0%)
Query: 5 AGPA-LAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKP 63
AGP+ A A PP+Q F+ P RP GT G+ IKL AN+FE+DIPKID+YHYE+DIKP
Sbjct: 3 AGPSGAAAGAYLPPLQ-QVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKP 61
Query: 64 EKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEG 123
+KCPRRVNRE+VE+MVQHFK QIFGDRKPV+DG+KN+YT LPIG ++V+ EVT+PGEG
Sbjct: 62 DKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEG 121
Query: 124 KDRIFKVSIKWVSCVSLQALHDAL-SGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFF 182
KDRIFKVSIKW++ VS + LH+AL SG++P VP E++QALDV MRHL SMRYTPVGRSFF
Sbjct: 122 KDRIFKVSIKWLAIVSWRMLHEALVSGQIP-VPLESVQALDVAMRHLASMRYTPVGRSFF 180
Query: 183 TASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKS 242
+ EG +PLGGGREVWFGFHQSVRP++WKMMLNIDVSATAFYKAQPVIEF+CEVLD ++
Sbjct: 181 SPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRN 240
Query: 243 IEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQ 302
I+EQ KPLTDSQRV+FTKEIKGLKVE+THCGQMKRKYRVCNVTRRPASHQTFPLQ ESGQ
Sbjct: 241 IDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQ 300
Query: 303 TVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTS 362
TVECTVAQYFK ++ L L+YPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTS
Sbjct: 301 TVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTS 360
Query: 363 TMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG 422
TMI+ATARSAPDRQEEIS+LM++AS+N DPY++EFGI VKD+MT+VTGRVL P + YGG
Sbjct: 361 TMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGG 420
Query: 423 RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAG 482
RN+AIATP QGVWDMR KQF+ GIEIKVWAIACFAPQ+QC E LK+FT+QLRKIS+DAG
Sbjct: 421 RNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAG 480
Query: 483 MPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGM 542
MPIQGQPCFCKYAQGADSVEPMFRHLKNTY+GLQL++VILPGKTPVYAEVKRVGDT+LGM
Sbjct: 481 MPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGM 540
Query: 543 ATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPP 602
ATQCVQ+KNV +T+PQTLSNLCLKINVKLGG+NNIL+P R VFQQPVIFLGADVTHPP
Sbjct: 541 ATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPP 600
Query: 603 AGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPT 662
AGDGKKPSI AVVGSMDAHP+RYCATVRVQ+ RQEII+DL+ MVRELLIQFYKSTRFKPT
Sbjct: 601 AGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPT 660
Query: 663 RIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNE 722
RIIFYRDGV EGQ Q+LH+ELLAIR+ACIKLEKDYQPGIT+IVVQKRHHTRLFC DKNE
Sbjct: 661 RIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNE 720
Query: 723 RVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQIL 782
R+GKSGNIPAGTTVDT ITHP EFDFYLCSHAGIQGTSRPSHY+VLWDDNRF++DELQIL
Sbjct: 721 RIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQIL 780
Query: 783 TYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQAL 842
TYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLVDKEHDS EGSH SGQSNGRD QAL
Sbjct: 781 TYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQAL 840
Query: 843 AKAVQVHQDTLRTMYFA 859
AKAVQVHQDTLRTMYFA
Sbjct: 841 AKAVQVHQDTLRTMYFA 857
>gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform
a [Homo sapiens]
Length = 860
Score = 1419 bits (3672), Expect = 0.0
Identities = 689/864 (79%), Positives = 768/864 (88%), Gaps = 18/864 (2%)
Query: 5 AGPALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPE 64
AGPA A P P RP +GT G+ IKL AN F+++IPKID+Y YE+DIKP+
Sbjct: 6 AGPAGAQPL---------LMVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYLYEVDIKPD 56
Query: 65 KCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEG- 123
KCPRRVNRE+V+ MVQHFK IFGDR+PV+DG+++LYTA PLP+ V+L+VTLPGEG
Sbjct: 57 KCPRRVNREVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGG 116
Query: 124 KDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFET--------IQALDVVMRHLPSMRYT 175
KDR FKVSIK+VS VS LH+ L+GR P E + A+DVV+RHLPSM+YT
Sbjct: 117 KDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYT 176
Query: 176 PVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVC 235
PVGRSFF+A EG +PLGGGREVWFGFHQSVRP++WKMMLNIDVSATAFYKAQPVI+F+C
Sbjct: 177 PVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMC 236
Query: 236 EVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFP 295
EVLD +I+EQ +PLTDS RVKFTKEIKGLKVE+THCG M+RKYRVCNVTRRPASHQTFP
Sbjct: 237 EVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFP 296
Query: 296 LQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK 355
LQ E+GQTVE TVAQYF++++ L L+YPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK
Sbjct: 297 LQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKK 356
Query: 356 LTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQP 415
LTDNQTSTMI+ATARSAPDRQEEIS+L+RSA++ TDP+V+EF V+DEM VTGRVL
Sbjct: 357 LTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPA 416
Query: 416 PSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLR 475
P + YGGRN+ +ATP GVWDMR KQFHTG+EIK+WAIACFA QRQC E LK FT+QLR
Sbjct: 417 PMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLR 476
Query: 476 KISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRV 535
KIS+DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTY+GLQL++VILPGKTPVYAEVKRV
Sbjct: 477 KISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRV 536
Query: 536 GDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLG 595
GDT+LGMATQCVQ+KNV +T+PQTLSNLCLKINVKLGG+NNIL+P RP VFQQPVIFLG
Sbjct: 537 GDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLG 596
Query: 596 ADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYK 655
ADVTHPPAGDGKKPSIAAVVGSMDAHP+RYCATVRVQ+ RQEIIQDLA+MVRELLIQFYK
Sbjct: 597 ADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYK 656
Query: 656 STRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRL 715
STRFKPTRIIFYRDGVSEGQF+QVL++ELLAIREACI LEKDYQPGIT+IVVQKRHHTRL
Sbjct: 657 STRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRL 716
Query: 716 FCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFS 775
FC D+ ERVG+SGNIPAGTTVDT ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN F+
Sbjct: 717 FCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFT 776
Query: 776 SDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSN 835
+DELQ+LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSH SGQSN
Sbjct: 777 ADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSN 836
Query: 836 GRDHQALAKAVQVHQDTLRTMYFA 859
GRD QALAKAVQ+HQDTLRTMYFA
Sbjct: 837 GRDPQALAKAVQIHQDTLRTMYFA 860
>gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo
sapiens]
Length = 861
Score = 1402 bits (3628), Expect = 0.0
Identities = 674/860 (78%), Positives = 761/860 (88%), Gaps = 16/860 (1%)
Query: 12 PAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVN 71
P PP + F+PP RP GT G+ I+L AN F++ IPKID+YHY++DIKPEK PRRVN
Sbjct: 6 PGPPASL----FQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYDVDIKPEKRPRRVN 61
Query: 72 REIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVS 131
RE+V+ MV+HFK QIFGDR+P +DG++N+YTA PLPIGRD+V++EVTLPGEGKD+ FKVS
Sbjct: 62 REVVDTMVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVS 121
Query: 132 IKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNP 191
++WVS VSLQ L +AL+G L VP +++QALDV+ RHLPSMRYTPVGRSFF+ EG +P
Sbjct: 122 VQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHP 181
Query: 192 LGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLT 251
LGGGREVWFGFHQSVRP++W MMLNIDVSATAFY+AQP+IEF+CEVLD ++I EQ KPLT
Sbjct: 182 LGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLT 241
Query: 252 DSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQY 311
DSQRVKFTKEI+GLKVE+THCGQMKRKYRVCNVTRRPASHQTFPLQ E+GQ +ECTVAQY
Sbjct: 242 DSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQY 301
Query: 312 FKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARS 371
FK ++ L L+YPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMI+ATARS
Sbjct: 302 FKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARS 361
Query: 372 APDRQEEISKLMRSASF--NTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIAT 429
APDRQEEIS+L++S S DPY++EFGI+V +EMT++TGRVL P + YGGRNK +AT
Sbjct: 362 APDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVAT 421
Query: 430 PVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQP 489
P QGVWDMR KQF+ GIEIKVWA+ACFAPQ+QC E LKSFT+QLRKIS+DAGMPIQGQP
Sbjct: 422 PNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQP 481
Query: 490 CFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQM 549
CFCKYAQGADSVEPMF+HLK TY GLQL+VVILPGKTPVYAEVKRVGDT+LGMATQCVQ+
Sbjct: 482 CFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQV 541
Query: 550 KNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKP 609
KNV +T+PQTLSNLCLKIN KLGG+NN+L+P RP VFQQPVIFLGADVTHPPAGDGKKP
Sbjct: 542 KNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKP 601
Query: 610 SIAAVVGSMDAHPNRYCATVRVQQHRQEI----------IQDLAAMVRELLIQFYKSTRF 659
SIAAVVGSMD HP+RYCATVRVQ RQEI IQDL MVRELLIQFYKSTRF
Sbjct: 602 SIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRF 661
Query: 660 KPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTD 719
KPTRII+YR GVSEGQ +QV EL+AIR+ACI LE+DY+PGIT+IVVQKRHHTRLFC D
Sbjct: 662 KPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCAD 721
Query: 720 KNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDEL 779
K ERVGKSGN+PAGTTVD+ ITHP+EFDFYLCSHAGIQGTSRPSHY VLWDDN F++DEL
Sbjct: 722 KTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADEL 781
Query: 780 QILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDH 839
Q+LTYQLCHTYVRCTRSVSIPAPAYYA LVAFRARYHLVDK+HDSAEGSH SGQSNGRD
Sbjct: 782 QLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDP 841
Query: 840 QALAKAVQVHQDTLRTMYFA 859
QALAKAVQ+H DT TMYFA
Sbjct: 842 QALAKAVQIHHDTQHTMYFA 861
>gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform
b [Homo sapiens]
Length = 626
Score = 1119 bits (2895), Expect = 0.0
Identities = 536/626 (85%), Positives = 585/626 (93%)
Query: 234 VCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQT 293
+CEVLD +I+EQ +PLTDS RVKFTKEIKGLKVE+THCG M+RKYRVCNVTRRPASHQT
Sbjct: 1 MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQT 60
Query: 294 FPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 353
FPLQ E+GQTVE TVAQYF++++ L L+YPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI
Sbjct: 61 FPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCI 120
Query: 354 KKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVL 413
KKLTDNQTSTMI+ATARSAPDRQEEIS+L+RSA++ TDP+V+EF V+DEM VTGRVL
Sbjct: 121 KKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVL 180
Query: 414 QPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQ 473
P + YGGRN+ +ATP GVWDMR KQFHTG+EIK+WAIACFA QRQC E LK FT+Q
Sbjct: 181 PAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQ 240
Query: 474 LRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVK 533
LRKIS+DAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTY+GLQL++VILPGKTPVYAEVK
Sbjct: 241 LRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK 300
Query: 534 RVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIF 593
RVGDT+LGMATQCVQ+KNV +T+PQTLSNLCLKINVKLGG+NNIL+P RP VFQQPVIF
Sbjct: 301 RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIF 360
Query: 594 LGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQF 653
LGADVTHPPAGDGKKPSIAAVVGSMDAHP+RYCATVRVQ+ RQEIIQDLA+MVRELLIQF
Sbjct: 361 LGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQF 420
Query: 654 YKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHT 713
YKSTRFKPTRIIFYRDGVSEGQF+QVL++ELLAIREACI LEKDYQPGIT+IVVQKRHHT
Sbjct: 421 YKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHT 480
Query: 714 RLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNR 773
RLFC D+ ERVG+SGNIPAGTTVDT ITHP EFDFYLCSHAGIQGTSRPSHYHVLWDDN
Sbjct: 481 RLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNC 540
Query: 774 FSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQ 833
F++DELQ+LTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSH SGQ
Sbjct: 541 FTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ 600
Query: 834 SNGRDHQALAKAVQVHQDTLRTMYFA 859
SNGRD QALAKAVQ+HQDTLRTMYFA
Sbjct: 601 SNGRDPQALAKAVQIHQDTLRTMYFA 626
>gi|66346725 piwi-like 1 [Homo sapiens]
Length = 861
Score = 168 bits (426), Expect = 2e-41
Identities = 193/800 (24%), Positives = 341/800 (42%), Gaps = 85/800 (10%)
Query: 32 GTSGRTIKLQANFFEMDI-PKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90
G+SG ++L N F + P+ +Y Y +D P RR+ ++ F+ + +
Sbjct: 106 GSSGIIVRLSTNHFRLTSRPQWALYQYHIDYNPLMEARRLRSALL------FQHEDLIGK 159
Query: 91 KPVFDGRKNLYTAMPLPIGRDKVELEV-TLPGEGKDRIFKVSIKWVSCVSLQALHDALSG 149
FDG T + LP + EV + G+D +++I L+
Sbjct: 160 CHAFDG-----TILFLPKRLQQKVTEVFSKTRNGED--VRITI-------------TLTN 199
Query: 150 RLPSVPFETIQALDVVMRHLPS-MRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRP 208
LP +Q +++ R L M +GR+++ ++ P +W GF S+
Sbjct: 200 ELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPNDPIDIP-SHRLVIWPGFTTSILQ 258
Query: 209 SLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVE 268
+ML DVS +++ V++F+ +F E+ K + + +KE+ GL V
Sbjct: 259 YENSIMLCTDVSHKVL-RSETVLDFM---FNFYHQTEEHK-----FQEQVSKELIGLVVL 309
Query: 269 ITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCL 328
+ + YRV ++ TF S E + +Y++ ++ + P L
Sbjct: 310 TKY---NNKTYRVDDIDWDQNPKSTFKKADGS----EVSFLEYYRKQYNQEITDLKQPVL 362
Query: 329 QVGQEQKH----------TYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPD-RQE 377
V Q ++ L E+C + K D + R P+ RQ
Sbjct: 363 -VSQPKRRRGPGGTLPGPAMLIPELCYLTG--LTDKMRNDFNVMKDLAVHTRLTPEQRQR 419
Query: 378 EISKLMR--SASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVW 435
E+ +L+ + N +R++G+ + +GR+LQ I GG+ P W
Sbjct: 420 EVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDY-NPQFADW 478
Query: 436 DMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYA 495
+ I +K R+ E S + L K++ GM ++
Sbjct: 479 SKETRGAPL-ISVKPLDNWLLIYTRRNYEA-ANSLIQNLFKVTPAMGMQMRKAIMI---- 532
Query: 496 QGADSVEPMFRHLKNTY-AGLQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQMKNV- 552
+ D E R L+ A Q+VV +L + Y +K+ T +QCV + +
Sbjct: 533 EVDDRTEAYLRVLQQKVTADTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLG 592
Query: 553 -QRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSI 611
Q+T + + L++N K+GG R + + V+ +G D H + SI
Sbjct: 593 KQQTVMAIATKIALQMNCKMGG------ELWRVDIPLKLVMIVGIDCYHDMTAGRR--SI 644
Query: 612 AAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGV 671
A V S++ R+ + Q QE++ L ++ L + + P+RII YRDGV
Sbjct: 645 AGFVASINEGMTRWFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGV 704
Query: 672 SEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIP 731
+GQ + ++++E+ + + + Y P +T IVV+KR +TR F + G+ N
Sbjct: 705 GDGQLKTLVNYEVPQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFA----QSGGRLQNPL 760
Query: 732 AGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYV 791
GT +D ++T P +DF++ S A G+ P+HY+V++D++ D +Q LTY+LCH Y
Sbjct: 761 PGTVIDVEVTRPEWYDFFIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYY 820
Query: 792 RCTRSVSIPAPAYYAHLVAF 811
+ +PAP YAH +AF
Sbjct: 821 NWPGVIRVPAPCQYAHKLAF 840
>gi|221316711 piwi-like 4 [Homo sapiens]
Length = 852
Score = 168 bits (425), Expect = 2e-41
Identities = 191/800 (23%), Positives = 344/800 (43%), Gaps = 88/800 (11%)
Query: 32 GTSGRTIKLQANFFEMDIPKI-DIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90
G+SG +KL N F +D P+ +Y Y + P+ RR+ ++ + ++
Sbjct: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALL------YSHSELSNK 153
Query: 91 KPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR--IFKVSIKWVSCVSLQALHDALS 148
FDG + K+E +VT R K++I L
Sbjct: 154 AKAFDGAILFLS--------QKLEEKVTELSSETQRGETIKMTI-------------TLK 192
Query: 149 GRLPSVPFETIQALDVVMRH-LPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVR 207
LPS IQ +++ R L + +GR+F+ SE P +W GF SV
Sbjct: 193 RELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHK-LSLWPGFAISVS 251
Query: 208 PSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKV 267
K++ + DVS + + V+EF+ + Q+ K++ GL V
Sbjct: 252 YFERKLLFSADVSYKVL-RNETVLEFMTALC--------QRTGLSCFTQTCEKQLIGLIV 302
Query: 268 EITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPC 327
+ R Y + ++ TF Q+ G E T Y+K ++ + + + P
Sbjct: 303 LTRY---NNRTYSIDDIDWSVKPTHTF--QKRDG--TEITYVDYYKQQYDITVSDLNQPM 355
Query: 328 L-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST--MIRATAR----SAPDRQEEIS 380
L + +++++ ++ +++ + LTD TS +++A A S RQ+ ++
Sbjct: 356 LVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLA 415
Query: 381 KLMRSASFNTDPY--VREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGV-W-- 435
+L+ + NT+ + +G+ +++ +TGR++ IL I PV W
Sbjct: 416 RLVDNIQRNTNARFELETWGLHFGSQIS-LTGRIVPSEKILMQDH---ICQPVSAADWSK 471
Query: 436 DMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYA 495
D+R + + W I C TE +SF LR+++ G +
Sbjct: 472 DIRTCKILNAQSLNTWLILC----SDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQE 527
Query: 496 QGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAE-VKRVGDTVLGMATQCVQMK--NV 552
A V + +++ +QLV+ ILP Y + +K+ + + +QCV + N
Sbjct: 528 NPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNK 584
Query: 553 QRTTPQTLSNLCLKINVKLGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSI 611
Q + + +++ KLGG + + +P + ++ +G DV K +
Sbjct: 585 QGMMMSIATKIAMQMTCKLGGELWAVEIPL-------KSLMVVGIDVCKDALS--KDVMV 635
Query: 612 AAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGV 671
V S++ R+ + +Q+ ++ L + L ++YK P RII YR GV
Sbjct: 636 VGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGV 695
Query: 672 SEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIP 731
+GQ + ++ +E+ + + + + ++ IVV+K+ R F T+ N V N P
Sbjct: 696 GDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFF-TEMNRTVQ---NPP 751
Query: 732 AGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYV 791
GT VD++ T +DFYL S +GT P++Y+V++DDN D +Q LT++LCH Y
Sbjct: 752 LGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLYY 811
Query: 792 RCTRSVSIPAPAYYAHLVAF 811
VS+PAP YAH + F
Sbjct: 812 NWPGIVSVPAPCQYAHKLTF 831
>gi|153792298 piwi-like 3 [Homo sapiens]
Length = 882
Score = 156 bits (395), Expect = 7e-38
Identities = 200/814 (24%), Positives = 345/814 (42%), Gaps = 105/814 (12%)
Query: 32 GTSGRTIKLQANFFEM-DIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90
G+ G ++L AN F + P+ Y Y +D KP+ + +++ QH + FG+R
Sbjct: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLD---QHRRK--FGER 173
Query: 91 KPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR-IFKVSIKWVSCVSLQALHDALSG 149
+FDG L + P+ +VE T KD+ I K+++++ S
Sbjct: 174 H-IFDGNSLLLSR---PLKERRVEWLSTT----KDKNIVKITVEF-------------SK 212
Query: 150 RLPSVPFETIQALDVVMRH-LPSMRYTPVGRSFFTASEGCS-NPLGGGREVWFGFHQSVR 207
L + ++ +++ R + + VGR+++T + G E+W G+ SV
Sbjct: 213 ELTPTSPDCLRYYNILFRRTFKLLDFEQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVL 272
Query: 208 PSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKV 267
+ L DVS IE + + S + Q T + R + T ++ G
Sbjct: 273 QYENSITLCADVSHKLLR-----IETAYDFIKRTSAQAQ----TGNIREEVTNKLIG--- 320
Query: 268 EITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPC 327
I + YRV ++ + TF S + T Y++ +HK ++ P
Sbjct: 321 SIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGS----KITYIDYYRQQHKEIVTVKKQPL 376
Query: 328 LQ---------VGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEE 378
L G +++ L ++C++ I K D + R +P R+
Sbjct: 377 LVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICK--DYSIVKELAKHTRLSPRRRHH 434
Query: 379 ISKLMRSASFNTDPYVRE----FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGV 434
K + + + VRE + + V GRVL+ +I+ G R + QG
Sbjct: 435 TLKEFIN-TLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIVQGRR--MVKANSQGD 491
Query: 435 W--DMRNKQFHTGIEIKVWAIACF-APQRQCTEV--HLKSFTEQLRKISRDAGMPIQGQP 489
W ++R + + W I + R+ + HL+S T A M I +P
Sbjct: 492 WSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVT---------APMGITMKP 542
Query: 490 CFCKYAQG-ADSVEPMFRHLKNTYAGLQL---------VVVILPGKTPV-YAEVKRVGDT 538
G A+S R K T LQ+ V+ ILP Y +KR T
Sbjct: 543 AEMIEVDGDANSYIDTLR--KYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYLCT 600
Query: 539 VLGMATQCVQMKNVQRTTPQTL-SNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGAD 597
+ +QCV K +++ +T+ + + ++N K+GG + Q +F+G D
Sbjct: 601 KCPIPSQCVVKKTLEKVQARTIVTKIAQQMNCKMGGA------LWKVETDVQRTMFVGID 654
Query: 598 VTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKST 657
H ++ SIA V S +A ++ + +Q+ +E++++L ++ L + K+
Sbjct: 655 CFHDIVN--RQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNE 712
Query: 658 RFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFC 717
P +I YRDGV +GQ Q +L HE + +K + FIVV+KR +TR F
Sbjct: 713 SSMPHSVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFL 771
Query: 718 TDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSD 777
+ N P GT +D ++T +DF++ S + GT P+HY+V++D S D
Sbjct: 772 ----KHGSNFQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPD 827
Query: 778 ELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 811
+Q LTY LCH Y + +PAP +YAH +A+
Sbjct: 828 TVQRLTYCLCHMYYNLPGIIRVPAPCHYAHKLAY 861
>gi|209180418 piwi-like 2 [Homo sapiens]
Length = 973
Score = 148 bits (374), Expect = 2e-35
Identities = 195/842 (23%), Positives = 345/842 (40%), Gaps = 103/842 (12%)
Query: 7 PALAPP--APPPPIQGYAFKPPPRP--------------DFGTSGRTIKLQANFFEMDIP 50
P+ PP + PP + P RP G+ G L N ++
Sbjct: 177 PSRGPPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCH 236
Query: 51 KIDIYHYELDIKPE-KCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIG 109
+Y Y + P +C + +H Q FDG + + LP+
Sbjct: 237 NEAVYQYHVTFSPNVECKSMRFGMLKDH-------QAVTGNVTAFDG-----SILYLPV- 283
Query: 110 RDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHL 169
K++ + L + K ++SIK L+ D +PF + V R +
Sbjct: 284 --KLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLC------IPFYNV----VFRRVM 331
Query: 170 PSMRYTPVGRSFFTASEGCSNPLGGGR-EVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQ 228
+ VGR+F+ + L R ++W G+ S+R + + L DVS
Sbjct: 332 KLLDMKLVGRNFYDPTSAMV--LQQHRLQIWPGYAASIRRTDGGLFLLADVS-------H 382
Query: 229 PVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRP 288
VI C + +I +Q K + + + TK + G + IT R YR+ +V
Sbjct: 383 KVIRNDCVLDVMHAIYQQNK---EHFQDECTKLLVG-NIVITRYNN--RTYRIDDVDWNK 436
Query: 289 ASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCL---------QVGQEQKHTYL 339
+F + E T +Y+ + + ++ P L G K L
Sbjct: 437 TPKDSFTMSDGK----EITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEIL 492
Query: 340 PLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFN---TDPYVRE 396
L + + G K + + S + L++ + N T+ +R
Sbjct: 493 LLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMR- 551
Query: 397 FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACF 456
+G+ ++ ++ + GRVL I + + + V ++ I + WA+ F
Sbjct: 552 WGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWAL--F 609
Query: 457 APQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAG-- 514
P+R + + L KI+ GM + P + + D +E R +++T
Sbjct: 610 YPKRAMDQA--RELVNMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
Query: 515 -LQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTP--QTLSNLCLKINVK 570
+Q+VV I+ G + +Y +K++ + +Q V ++ + + T + L+IN K
Sbjct: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
Query: 571 LGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATV 629
LGG + + +P + ++ +G DV H P+ + S+ V S++ ++ + V
Sbjct: 725 LGGELWGVDIPL-------KQLMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
Query: 630 RVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIRE 689
Q QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V ++E+ +++
Sbjct: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Query: 690 ACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFY 749
C + ++YQP + VVQK+ T L+ V + GT VD IT DFY
Sbjct: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
Query: 750 LCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLV 809
L +H QG P+HY + + S D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
Query: 810 AF 811
AF
Sbjct: 951 AF 952
>gi|24431985 piwi-like 2 [Homo sapiens]
Length = 973
Score = 148 bits (374), Expect = 2e-35
Identities = 195/842 (23%), Positives = 345/842 (40%), Gaps = 103/842 (12%)
Query: 7 PALAPP--APPPPIQGYAFKPPPRP--------------DFGTSGRTIKLQANFFEMDIP 50
P+ PP + PP + P RP G+ G L N ++
Sbjct: 177 PSRGPPQLSSPPALPQSPLHSPDRPLVLTVEHKEKELIVKQGSKGTPQSLGLNLVKIQCH 236
Query: 51 KIDIYHYELDIKPE-KCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIG 109
+Y Y + P +C + +H Q FDG + + LP+
Sbjct: 237 NEAVYQYHVTFSPNVECKSMRFGMLKDH-------QAVTGNVTAFDG-----SILYLPV- 283
Query: 110 RDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHL 169
K++ + L + K ++SIK L+ D +PF + V R +
Sbjct: 284 --KLQQVLELKSQRKTDSAEISIKIQMTKILEPCSDLC------IPFYNV----VFRRVM 331
Query: 170 PSMRYTPVGRSFFTASEGCSNPLGGGR-EVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQ 228
+ VGR+F+ + L R ++W G+ S+R + + L DVS
Sbjct: 332 KLLDMKLVGRNFYDPTSAMV--LQQHRLQIWPGYAASIRRTDGGLFLLADVS-------H 382
Query: 229 PVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRP 288
VI C + +I +Q K + + + TK + G + IT R YR+ +V
Sbjct: 383 KVIRNDCVLDVMHAIYQQNK---EHFQDECTKLLVG-NIVITRYNN--RTYRIDDVDWNK 436
Query: 289 ASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCL---------QVGQEQKHTYL 339
+F + E T +Y+ + + ++ P L G K L
Sbjct: 437 TPKDSFTMSDGK----EITFLEYYSKNYGITVKEEDQPLLIHRPSERQDNHGMLLKGEIL 492
Query: 340 PLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFN---TDPYVRE 396
L + + G K + + S + L++ + N T+ +R
Sbjct: 493 LLPELSFMTGIPEKMKKDFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMR- 551
Query: 397 FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACF 456
+G+ ++ ++ + GRVL I + + + V ++ I + WA+ F
Sbjct: 552 WGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWAL--F 609
Query: 457 APQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAG-- 514
P+R + + L KI+ GM + P + + D +E R +++T
Sbjct: 610 YPKRAMDQA--RELVNMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 664
Query: 515 -LQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTP--QTLSNLCLKINVK 570
+Q+VV I+ G + +Y +K++ + +Q V ++ + + T + L+IN K
Sbjct: 665 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 724
Query: 571 LGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATV 629
LGG + + +P + ++ +G DV H P+ + S+ V S++ ++ + V
Sbjct: 725 LGGELWGVDIPL-------KQLMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 775
Query: 630 RVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIRE 689
Q QEI+ L + L +FY+ P +I+ YRDGVS+GQ + V ++E+ +++
Sbjct: 776 VFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIVVYRDGVSDGQLKTVANYEIPQLQK 835
Query: 690 ACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFY 749
C + ++YQP + VVQK+ T L+ V + GT VD IT DFY
Sbjct: 836 -CFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVTPT----PGTVVDHTITSCEWVDFY 890
Query: 750 LCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLV 809
L +H QG P+HY + + S D +Q LT++LCH Y ++ +PAP YAH +
Sbjct: 891 LLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHMYWNWPGTIRVPAPCKYAHKL 950
Query: 810 AF 811
AF
Sbjct: 951 AF 952
>gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo
sapiens]
Length = 349
Score = 49.7 bits (117), Expect = 1e-05
Identities = 58/269 (21%), Positives = 120/269 (44%), Gaps = 23/269 (8%)
Query: 397 FGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACF 456
+G+ ++ ++ + GRVL I + + + V ++ I + WA+ F
Sbjct: 46 WGLRLQKDVHKIEGRVLPMERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWAL--F 103
Query: 457 APQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAG-- 514
P+R + + L KI+ GM + P + + D +E R +++T
Sbjct: 104 YPKRAMDQA--RELVNMLEKIAGPIGMRMS-PPAWVELKD--DRIETYVRTIQSTLGAEG 158
Query: 515 -LQLVVVILPG-KTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTP--QTLSNLCLKINVK 570
+Q+VV I+ G + +Y +K++ + +Q V ++ + + T + L+IN K
Sbjct: 159 KIQMVVCIIMGPRDDLYGAIKKLCCVQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCK 218
Query: 571 LGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATV 629
LGG + + +P + ++ +G DV H P+ + S+ V S++ ++ + V
Sbjct: 219 LGGELWGVDIPL-------KQLMVIGMDVYHDPSRGMR--SVVGFVASINLTLTKWYSRV 269
Query: 630 RVQQHRQEIIQDLAAMVRELLIQFYKSTR 658
Q QEI+ L + L +FY++ +
Sbjct: 270 VFQMPHQEIVDSLKLCLVGSLKKFYEAAQ 298
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 33.5 bits (75), Expect = 0.87
Identities = 16/32 (50%), Positives = 18/32 (56%), Gaps = 1/32 (3%)
Query: 4 GAGPALAPPAPPPPIQGYAFKPPPRPDFGTSG 35
G P APP PPPP+ G PPP FG+ G
Sbjct: 315 GFAPPPAPPPPPPPMIGIP-PPPPPVGFGSPG 345
>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
potassium channel 2 [Homo sapiens]
Length = 889
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/26 (53%), Positives = 14/26 (53%)
Query: 4 GAGPALAPPAPPPPIQGYAFKPPPRP 29
GA PA PP PPPP PPP P
Sbjct: 15 GATPAPGPPPPPPPAPPQQQPPPPPP 40
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 32.7 bits (73), Expect = 1.5
Identities = 15/33 (45%), Positives = 15/33 (45%)
Query: 3 SGAGPALAPPAPPPPIQGYAFKPPPRPDFGTSG 35
SG P PP PPPP PPP P G G
Sbjct: 182 SGPPPPPPPPVPPPPTGATPPPPPPLPAGGAQG 214
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 32.7 bits (73), Expect = 1.5
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 8 ALAPPAPPPPIQGYAFKPPPRP 29
+L PP PPPP+ G PPP P
Sbjct: 547 SLLPPPPPPPLPGGMLPPPPPP 568
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 32.3 bits (72), Expect = 1.9
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 6 GPALAPPAPPPPIQGYAFKPPPR 28
GP PP PPPP+ G PPP+
Sbjct: 837 GPLPPPPPPPPPVPGPVTLPPPQ 859
>gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens]
Length = 689
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/33 (48%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
Query: 4 GAGPALAPPAPPPPIQGYAFKPPPRPDFGTSGR 36
G G L PPAPP P GY P RP G G+
Sbjct: 119 GGGTELGPPAPPRPRNGY---QPHRPPGGGGGK 148
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 32.0 bits (71), Expect = 2.5
Identities = 29/104 (27%), Positives = 39/104 (37%), Gaps = 19/104 (18%)
Query: 10 APPAPPPPIQGY-------------AFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYH 56
AP PPPP+ KPPP G + N E IP Y
Sbjct: 1605 APVLPPPPVHSSIPPPGPVPMGMPPMSKPPPVQQTVDYGHGRDISTNKVE-QIP----YG 1659
Query: 57 YELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNL 100
+ ++P+ P R E EH Q + DR+P FD + N+
Sbjct: 1660 ERITLRPDPLPERSTFE-TEHAGQRDRYDRERDREPYFDRQSNV 1702
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 31.6 bits (70), Expect = 3.3
Identities = 12/19 (63%), Positives = 13/19 (68%), Gaps = 2/19 (10%)
Query: 11 PPAPPPPIQGYAFKPPPRP 29
PP PPPP+ GY PPP P
Sbjct: 293 PPGPPPPVPGYG--PPPGP 309
>gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
sapiens]
Length = 1583
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 524 GKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGR 583
G +Y+ ++V + G A + K P TL C + GG +I+ G+
Sbjct: 179 GAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATL--FCFAVRNPTGGKLHII-EVGQ 235
Query: 584 PPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGS 617
P QP + DV PP P +A +G+
Sbjct: 236 PAAGNQPFVKKAVDVFFPPEAQNDFP-VAMQIGA 268
>gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo
sapiens]
Length = 1640
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 4/94 (4%)
Query: 524 GKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGR 583
G +Y+ ++V + G A + K P TL C + GG +I+ G+
Sbjct: 179 GAMQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATL--FCFAVRNPTGGKLHII-EVGQ 235
Query: 584 PPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGS 617
P QP + DV PP P +A +G+
Sbjct: 236 PAAGNQPFVKKAVDVFFPPEAQNDFP-VAMQIGA 268
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 31.6 bits (70), Expect = 3.3
Identities = 22/79 (27%), Positives = 32/79 (40%), Gaps = 24/79 (30%)
Query: 7 PALAPPAPPPPIQGYAFKPPPRP---------DFGTSGRTIKLQANFFEMDIPKIDI--- 54
P+ PP PPPP+ G PPP P + G+ K +FF IP+ +
Sbjct: 55 PSSPPPPPPPPLPGEPPIPPPPPGLPPTTHMNGYSHLGKK-KRMRSFFWKTIPEEQVRGK 113
Query: 55 -----------YHYELDIK 62
+HY++D K
Sbjct: 114 TNIWTLAARQEHHYQIDTK 132
>gi|5729962 submaxillary gland androgen regulated protein 3
homolog B [Homo sapiens]
Length = 79
Score = 31.6 bits (70), Expect = 3.3
Identities = 12/27 (44%), Positives = 13/27 (48%)
Query: 6 GPALAPPAPPPPIQGYAFKPPPRPDFG 32
GP PP PPPP PPP +G
Sbjct: 42 GPGFVPPPPPPPYGPGRIPPPPPAPYG 68
>gi|22035556 transcription initiation factor IIIB isoform 1 [Homo
sapiens]
Length = 677
Score = 31.2 bits (69), Expect = 4.3
Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 15/95 (15%)
Query: 776 SDELQILTYQLCHTYVRCTRSVSIPAPAY--------YAHLVAFRARYHLVDK------E 821
SD LQ+ Y L T++ R + I APA +AHL+ F + H V +
Sbjct: 153 SDLLQVNVYVLGKTFLLLARELCINAPAIDPCLYIPRFAHLLEFGEKNHEVSMTALRLLQ 212
Query: 822 HDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTM 856
+ HT + +G AL A ++H D RT+
Sbjct: 213 RMKRDWMHTGRRPSGLCGAALLVAARMH-DFRRTV 246
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 30.8 bits (68), Expect = 5.6
Identities = 13/23 (56%), Positives = 14/23 (60%), Gaps = 1/23 (4%)
Query: 9 LAPPAPPPPIQGYAFKPPPRPDF 31
L PP PPPP+ PPP PDF
Sbjct: 554 LPPPPPPPPLDDPELPPPP-PDF 575
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 30.8 bits (68), Expect = 5.6
Identities = 24/68 (35%), Positives = 30/68 (44%), Gaps = 11/68 (16%)
Query: 7 PALAPPAPPPPIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKID----IYHYELD-I 61
P L P PPPP PPP P SG+ + Q E K + I EL+
Sbjct: 3112 PLLQTPPPPPP------PPPPPPSSSLSGQQTEQQNKESEKKQTKPNKVKKIKEEELEAT 3165
Query: 62 KPEKCPRR 69
KPEK P++
Sbjct: 3166 KPEKHPKK 3173
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 30.8 bits (68), Expect = 5.6
Identities = 15/29 (51%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 2 YSGAGPALAPPAPPPPIQGYAFKPPPRPD 30
Y G GP APP PPPP + A P PD
Sbjct: 773 YPGRGPPPAPPPPPPPPRAPA-DPAASPD 800
>gi|57863314 vacuolar protein sorting 37C [Homo sapiens]
Length = 355
Score = 30.8 bits (68), Expect = 5.6
Identities = 12/21 (57%), Positives = 12/21 (57%)
Query: 9 LAPPAPPPPIQGYAFKPPPRP 29
L PP PP P Y F PPP P
Sbjct: 330 LQPPYPPGPAPPYGFPPPPGP 350
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 30.8 bits (68), Expect = 5.6
Identities = 12/23 (52%), Positives = 14/23 (60%)
Query: 7 PALAPPAPPPPIQGYAFKPPPRP 29
P L PP PPP +Q A +P P P
Sbjct: 438 PPLPPPTPPPTLQPPALQPTPLP 460
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 30.4 bits (67), Expect = 7.3
Identities = 15/30 (50%), Positives = 15/30 (50%), Gaps = 4/30 (13%)
Query: 4 GAG----PALAPPAPPPPIQGYAFKPPPRP 29
GAG P PP PPPP G PPP P
Sbjct: 387 GAGGPPMPPPPPPPPPPPSSGNGPAPPPLP 416
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,549,748
Number of Sequences: 37866
Number of extensions: 1713094
Number of successful extensions: 7986
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 7587
Number of HSP's gapped (non-prelim): 413
length of query: 859
length of database: 18,247,518
effective HSP length: 111
effective length of query: 748
effective length of database: 14,044,392
effective search space: 10505205216
effective search space used: 10505205216
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.